Relevant bibliographies by topics / Methanol leaf extract

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Methanol leaf extract'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Methanol leaf extract"

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Sapkota, Sujana, Alishma Maharjan, Sanjeeta Tiwari, and Meena Rajbhandari. "Phytochemical Analysis, Antioxidant Potential and Antibacterial Activities of Different Anatomical Parts of Hypericum cordifolium Choisy." Scientific World Journal 2024 (May 25, 2024): 1–11. http://dx.doi.org/10.1155/2024/8128813.

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The genus Hypericum comprises a large number of species. The flower, leaf, stem, and root of the Hypericum species are widely used in traditional medicine in different cultures. Many Hypericum species have been well investigated phytochemically and pharmacologically. However, only a few reports are available on the H. cordifolium native to Nepal. The present study aims to evaluate the phytochemical composition of different extracts, qualitative analysis of methanol extract of the flower and leaf using thin-layer chromatography (TLC), and the antioxidant properties of components by the TLC-DPPH
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Lenny, Sovia, Murni Suryani Lumbantoruan, and Helmina Br Sembiring. "Antioxidant Activity Assay of Eucalyptus pellita Leaf Extract." International Journal of Ecophysiology 5, no. 2 (2023): 26–33. http://dx.doi.org/10.32734/ijoep.v5i2.13715.

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In pharmacy, eucalyptus leaves are used for various pharmacological activities because they contain phenolic compounds. This study aims to detect phytochemical compounds and test the antioxidant activity of Eucalyptus pellita leaf extract. The dry powder of E. pellita leaves (1900 g) was macerated first with methanol solvent. The concentrated methanol extract was then subjected to partition extraction with n - hexane solvent. The methanol layer was concentrated and then partitioned with ethyl acetate solvent. Methanol extract was obtained as much as 176.75 g (9,30%), n-hexane extract 13.77 g (
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Suresh, B., S. Shabana, M. Satya Prasad, M. R. Darukamallia, and A. Krishna Satya. "Phytochemical Studies and GC-MS Analysis of Tinospora Formanii Leaf Extracts." International Journal for Research in Applied Science and Engineering Technology 11, no. 9 (2023): 237–49. http://dx.doi.org/10.22214/ijraset.2023.55641.

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Abstract: The present study deals with the phytochemical aspects of Tinospora formanii. Crude leaf extracts were prepared with different solvents such as hexane, chloroform, methanol, and water using a Soxhlet apparatus. Qualitative and quantitative phytochemical studies and GC-MS analysis of leaf extracts have been carried out. Phytochemical studies showed that methanol leaf extract showed the presence of alkaloids, flavonoids, phenols, sterols, phytosterols, terpenoids, Tannins, saponins, glycosides, carbohydrates Anthraquinones, coumarins, Amino acids. Quantitative estimation showed that th
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Sati, S. C., and Savita Joshi. "Antibacterial Activities ofGinkgo bilobaL. Leaf Extracts." Scientific World JOURNAL 11 (2011): 2237–42. http://dx.doi.org/10.1100/2011/545421.

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The antibacterial activity of methanol, ethanol, chloroform, and hexane extracts of the leaves of Himalayan gymnospermous plantGinkgo bilobaL. was assessed against five animal and plant pathogenic strains (Agrobacterium tumefaciens, Bacillus subtilis, Escherichia coli, Erwinia chrysanthemi, and Xanthomonas phaseoli) employing disc-diffusion and broth-dilution assays. The methanol extract showed the highest activity (zone of inhibition of 15–21 mm) followed by ethanol (14–19 mm), chloroform (15–20 mm), and hexane (14–19 mm) extracts at 250 μg/mL. A minimum inhibitory concentration (MIC) of 7.8
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Giri, Dil Prakash, and Meena Rajbhandari. "PHYTOCHEMICAL ANALYSIS AND CONSTITUENTS OF HEXANE EXTRACT OF MELASTOMA MALABATHRICUM L." Journal of Institute of Science and Technology 23, no. 1 (2018): 18–25. http://dx.doi.org/10.3126/jist.v23i1.22150.

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Hexane, dichloromethane, ethyl acetate, methanol and 50 % aqueous methanol extracts of leaf, flower and fruit of Melastoma malabathricum were screened for the presence of different classes of phytochemicals. In phytochemical screening, ethyl acetate, methanol and 50 % aqueous methanol extracts showed the presence of phenolics and flavonoids. Glycosides were found only in the 50 % methanol extract of fruit. Free radical scavenging activity of methanol extract of leaf, flower and fruit was determined using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical. Total phenolic content was measured spe
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Hernández-Fernández, Adrián, Yolanda Garrido, Eduardo Iniesta-López, Antonia Pérez de los Ríos, Joaquín Quesada-Medina, and Francisco José Hernández-Fernández. "Recovering Polyphenols in Aqueous Solutions from Olive Mill Wastewater and Olive Leaf for Biological Applications." Processes 11, no. 9 (2023): 2668. http://dx.doi.org/10.3390/pr11092668.

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Olive leaf and olive mill wastewater are wastes which are produced in olive industry and can be used to obtain value-added products such as polyphenols. In this work, extracts of polyphenols from olive mill wastewater and olive leaf in an aqueous medium are obtained and their composition in polyphenols were determined and compared with those obtained using the conventional extract agent (methanol–water). The antioxidant capacity of the aqueous extracts of olive mill wastewater and olive leaf were also analysed. It was observed that the olive mill wastewater extracted in water provides a simila
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Fabowale, P. O., O. Agunloye, and C. I. Adekannbi. "Comparative Screening of Phytochemicals and Bioactive Compounds of Trema orientalis (Linn. Blume) Leaf and Bark Extracts." Asian Journal of Research in Biochemistry 13, no. 2 (2023): 7–16. http://dx.doi.org/10.9734/ajrb/2023/v13i2251.

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This study compared the phytochemical constituents of the leaf with the Bark extracts of T. orientalis, using the same extraction solvents. The leaf and Bark of T. orientalis were harvested at Federal University of Technology, Akure forest, dried and pulverized into powder. Extract were prepared from the powdered plants using Methanol and N-hexane. The qualitative and quantitative phytochemical presents in the extracts were determined. The functional compounds of the leaf extract were determined by Fourier Transmission Infrared Spectrometry (FT-IR). Percentage yield of Methanol was better than
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R. Nair, Lekshmy, and M. Balasubrahmanian. "Correlation Between Phytochemicals and Antioxidant Activities of Different Leaf Extracts of Entada rheedii." Journal of Plant Science Research 39, no. 1 (2023): 199–208. http://dx.doi.org/10.32381/jpsr.2023.39.01.20.

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The main aim of this study was to determine Total Phenolic Content, Total Flavonoid Content, terpenoid content, steroid content and analyze the antioxidant activity of different leaf extracts of Entada rheedii. Correlation between antioxidant activities and total phenolic content, total flavonoids content, terpenoid content and steroid content were also analyzed. The total phenolic content in E. rheedii hexane, ethyl acetate, methanol, and aqueous leaf extracts were found to be 10.16 mg GAE/g, 24.73 mg GAE/g, 26.11 mg GAE/g, and 24.85 mg GAE/g sample dry weight respectively. The Total flavonoi
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Gunyakti, Ayse, Meltem Asan-Ozusaglam, and Muhammad Mujtaba. "Assessment of Biological and Antioxidant Capacities of Myrtuscommunis L. Leaf and Fruit Extracts from Mediterranean Region of Turkey." Journal of Microbiology and Biotechnology Research 7, no. 3 (2017): 16. http://dx.doi.org/10.24896/jmbr.2017733.

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Recently in humans and fishes most of the disease causing pathogenic microorganisms developed resistance against certain antimicrobial agents. This situation is causing both health and economic problems. In this context present study was designed to evaluate the antimicrobial and antioxidant activities of leaves and fruits of Myrtuscommunis. Antimicrobial activity of the plant’s leaf and fruit extracts was tested by using disc diffusion method against five fish, seven food-borne human pathogens and twoyeast strains. For this purpose, n-hexane and methanol an organic solvent were used for the o
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Patel, Geetha, Harshita M., Sathi D., and Padmaa M. Paarakh. "ANTICANCER STUDIES ON THE LEAVES OF TINOSPORA CORDIFOLIA (WILD) MIERS." International Journal of Advanced Research 10, no. 10 (2022): 1029–35. http://dx.doi.org/10.21474/ijar01/15578.

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The aim of the study was to evaluate anticancer activity of the methanol and aqueous extracts of leaves of Tinosporacordifolia Wild Miers against a Human Breast Carcinoma Cell line(MDAMB231) by MTT assay. The coarse powder of leaf were subjected to Soxhletextraction and microwave assisted extraction using methanol and water as solvent. The IC50 values of aqueous extract of leaf followed by soxhlation and methanol extract of leaf by microwave extraction were found to be 59.85μg/mL and 249μg/mLrespectively in MDAMB231 cells in comparison to Standard Vincristine 14.41µM whereas methanol extrac
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Dissertations / Theses on the topic "Methanol leaf extract"

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Bekale, Raymonde Bamboukou. "Investigation of the antidiabetic activity of Cnicusbenedictus L. in rats." University of the Western Cape, 2016. http://hdl.handle.net/11394/5455.

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Magister Pharmaceuticae - MPharm<br>Diabetes Mellitus, one of the major diseases affecting human population all over the world has caused significant morbidity and mortality. The management of this condition has raised the demand of safe and cost effective remedial measures due to several side effects associated with the present use of modern medicines. Thus, it is crucial to explore other options for diabetes management such as the use of medical plants. Cnicus benedictus L. is one of the known plant species used by traditional medicine practitioners in South Africa for the treatment of
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Chiu, Yung-Fang, and 邱永芳. "The effect of lotus leaf methanolic extract on obese rat." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/50758292317685701784.

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碩士<br>臺灣大學<br>食品科技研究所<br>95<br>Obesity has been a universal concern because it can be the cause of a lot of disease. The aim of our research is to estimate the effect of lotus leaf which is often used as diet tea in Chinese herbs on reducing body fat. According to the Compendium of Materia Medica, a classic book of Chinese herbs, lotus leaf has a curing effect on obesity. In our experiment, we divided 60 SD rats into two groups, control and experiment group. In the control group we fed the rats with Purina 5001 commercial diet (3.4kcal/g). In the experiment group we fed the rats with high-e
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Wu, Yi-Chuan, and 吳宜娟. "Effects of Lotus Leaf Methanolic Extract on Pancreatic Lipase Activity and Differentiation of 3T3-L1 Preadipocytes." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/36430238472993842798.

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碩士<br>臺灣大學<br>食品科技研究所<br>95<br>Obesity is the most common nutritional disorder and it is considered to be a risk factor associated with the development of the major human diseases, including cardiovascular disease, diabetes, and cancer. It is an important topic in the world of public health and preventive medicine. It has close relations with lipid absorption and pancreatic lipase activity. The differentiation of 3T3-L1 preadipocytes plays an important role on the mechanism of adipogenesis. In the research about lotus (Nelumbo nucifera Gaertn.) leaf methanolic extract (LLM) on pancreatic lipas
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Chen, Yu-Jen, and 陳宥任. "Effect of leaf essential oil and methanolic extracts from Eucalyptus citriodora on the growth of Mikania micrantha and its inhibition mechanisms." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/62027610263783098771.

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碩士<br>國立中興大學<br>森林學系所<br>102<br>Allelopathy is most commonly used to describe the chemical interaction between two plants, it has also been used to describe microbe-microbe, plant-microbe and plant-insect or plant-herbivore chemical communication. Allelopathy can be applied for weed removal. In this study we examined the allelopathic mechanism of growth suppression of Mikania micrantha by the major allelochemicals of Eucalyptus citriodora leaf essential oil and methanolic extracts. Results of GC/MS analysis the major components of E. citriodora leaf essential oil was mainly as oxygenated m
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Book chapters on the topic "Methanol leaf extract"

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Afolayan, Michael O., Rebecca O. Omosimua, Adewale E. Fadeyi, Onyinye C. Aguzue, Olayinka T. Asekun, and Oluwole B. Familoni. "Phytochemical, Antioxidant, and Flavonoid Investigation of Methanolic Leaf Extract of Piliostigma thonningii (Schum.)." In Springer Protocols Handbooks. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2683-2_1.

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López-Rosas, Carlos Alberto, Seojin Han, Margarita V. Saavedra Vélez, José Rafael Alanis Gómez, and Fabiola Hernández-Rosas. "Biomedical Potential of the Methanolic Leaf Extract of Verbesina persicifolia: Antimicrobial Properties and Applications in Wound Healing." In IFMBE Proceedings. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-96538-8_24.

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Panda, Sagorika, Kalpita Bhatta, Himansu Bhusan Samal, and Pratikshya Mohanty. "Profiling of bioactive compounds in methanolic leaf extract of Artemisia nilagirica (C.B.Cl) Pamp. through GC-MS and In-silico study of some selected compound." In Advancement in Animal Handling and Generative AI for Pre-clinical Studies. CRC Press, 2025. https://doi.org/10.1201/9781003672869-9.

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Kanchana, Parijatham, Devasani Vaishnavi, and Y. Sabitha. "Antibiofilm and Antimicrobial Activity of Indigofera Tirunelvelica and Basella Alba." In Convergence of Technology & Biology - Transforming Life Sciences. Shanlax Publications, 2025. https://doi.org/10.34293/ctbtls.2025.ch012.

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The objective of this research is to compare the anti- biofilm and antimicrobial activity of Indigofera tirunelvelica and Basella alba. This study helps us to understand the anti-biofilm activity &amp; antimicrobial of extracts from Indigofera tirunelvelica and Basella alba against common biofilm-forming bacteria, such as Escherichia coli, Streptococcus pneumonia, Klebsiella pneumoniae, and Bacillus thuringiensis and biofilmforming fungi, such as Aspergillus Niger and Canadian. For this experimentation, leaf extract (methanol, chloroform &amp; aqueous) of Indigofera tirunelvelica and Basella a
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Resool Hussein, Malik Yahia Abdul, Narender Malothu, and Haritha Lanka. "Phytochemical Study, in Vitro Antioxidant and Antidiabetic Activity of Methonalic Leaf Extract of Linderina Parviflora." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00656.

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In a general context, the significance of a number of medicinal plants has been investigated in the treatment of diabetes mellitus. In this regard, to establish the anti-diabetic potential of Linderina Parviflora, one of the medicinal herbs this study was initiated. The main objective of the study was to evaluate the in vitro anti-oxidant and anti-diabetic activity of methanolic extracts of Linderina Parviflora leaves. During screening for phytochemicals the total phenolic and flavonoid content was estimated. In vitro antidiabetic activity was assessed by α-glucosidase and α-amylase inhibitory
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Thangaraj, Parimelazhagan, Pezzuto M. John, Tamara P. Kondratyuk, Eun-Jung Park, Murugan Rajan, and Simeon O. Kotchoni. "Inhibition of Nitric Oxide and Free Radical Production by Leaf and Stem Extracts of Psychotria nilgiriensis." In Bioactive Compounds from Medicinal Plants for Cancer Therapy and Chemoprevention. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815238549124010008.

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Psychotria nilgiriensis was used in traditional medicine as to cure chronic inflammatory diseases. Therefore, the evaluation of different combination of solventbased fractions from stem and leaves of P. nilgiriensis for free radical scavenging activity, inhibitory potential against nitric oxide radicals, and tentative identification of active metabolites were carried out. The antioxidant activity of solvent extracts was determined by DPPH· scavenging, TAC, and ORAC assays using spectrophotometer analysis. Further, nitric oxide production inhibition was studied in lipopolysaccharide (LPS)-activ
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Akintola, A. O., B. D. Kehinde, P. B. Ayoola, et al. "Advanced Study on Antioxidant Properties of Silver Nanoparticles Biosynthesized from Methanolic Leaf Extract of Blighia sapida." In New Approaches in Engineering Research Vol. 4. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/naer/v49023d.

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Muazu, Muhammed, Abdulsalami Mohammed Sani, Karderam Bukar Dikwa, Deborah Madi Dibal, Kokori Bajeh Tijani, and Junaidu Yahaya. "Antiplasmodial Potentials and GC-MS Analysis of Bioactive Compounds in Methanol and Ethanol Leaf Extracts of Daniellia oliveri." In Research Advances in Microbiology and Biotechnology Vol. 7. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/ramb/v7/6630b.

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Shaba, P., N. P. Kurade, V. Bhanupraksah, and R. K. Singh. "Evaluation of Methanolic Leaf Extract of Parkia biglobosa (African locust bean, Jacg, Benth) Leaves against Trypanosoma evansi." In Technological Innovation in Pharmaceutical Research Vol. 10. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/tipr/v10/7218d-2.

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Njateng, Guy Sedar Singor, and Jamshed Iqbal. "Investigating the Antidiabetic Potential of Methanolic Leaf Extracts of Piper umbellatum L. and Persea americana Mill." In Medical Research and Its Applications Vol. 9. B P International, 2024. http://dx.doi.org/10.9734/bpi/mria/v9/7785e.

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Conference papers on the topic "Methanol leaf extract"

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Wijesekara, Anupaja, S. R. M. M. Lanka Kumari, and Jagath Kasturiarachchi. "A Study on Anti bacterial Properties of Costus speciosus." In SLIIT INTERNATIONAL CONFERENCE ON ADVANCEMENTS IN SCIENCES AND HUMANITIES. Faculty of Humanities & Sciences, SLIIT, 2024. https://doi.org/10.54389/rrmm7674.

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Anti biotic resistant bacteria have posed a serious threat to world health in recent years, forcing the investigation of alternate sources for anti bacterials. Higher plants are a key source of medicinal compounds. The objective of this study was to evaluate the anti bacterial properties of C. speciosus against gram-negative E. coli and gram-positive Staphylococcus aureus, to explore its potential as a natural alternative to conventional anti bioti cs. Leaves, stems, and rhizomes of C. speciosus were extracted using hexane, methanol, and water as solvents with reflux, sonication and maceratio.
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Hasyim, Saiyidah Nafisah, Norrizah Jaafar Sidik, Tay Chia Chay, Nur Nadirah Rodzali, Siti Nur Azmu’i Abdullah, and Noor Amira Muhammad. "Phytochemical Compounds and Antioxidants Analysis of <i>Clinacanthus nutans </i>Leaf and Stem Extracts." In International Conference on Nanoscience and Nanotechnology 2022. Trans Tech Publications Ltd, 2023. http://dx.doi.org/10.4028/p-9qsg4u.

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Clinacanthus nutans consists with multiple medicinal properties. The plant is also known to be a source of biologically active compounds, particularly those with an antioxidant capacity. The phytochemical studies of C. nutans plant extract was mostly reported from its leaf part. Thus, the objectives of this study are to assess the phytochemical constituents and antioxidant activity of C. nutans leaf and stem. Methanol was used as solvent for the green extraction. Next, phytochemical screening, Fourier transform infrared (FTIR) analysis, total phenolic (TPC) and flavonoids contents (TFC), querc
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Kurang, Rosalina Y. "Phytochemical analysis and antioxidant activity of the methanol extract of Kersen leaf (Muntingia calabura L)." In 3RD INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0062175.

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Kamal, Irena, Hermansyah Hermansyah, Desnelli Desnelli, Muharni Muharni, and Yosie Andriani. "Sungkai (Peronema canescens Jack) Leaf Methanol Extract for Proliferation of Saccharomyces cerevisiae Yeast and Mice (Mus muculus)." In Proceedings of the 3rd Sriwijaya International Conference on Basic and Applied Sciences, SICBAS 2023, November 3, 2023, Palembang, Indonesia. EAI, 2024. http://dx.doi.org/10.4108/eai.3-11-2023.2347957.

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Djelic, Gorica, Milica Pavlović, Snežana Branković, Duško Brković, Zoran Simić, and Vesna Veličković. "CONTRIBUTION TO THE KNOWLEDGE OF THE ANTIOXIDANT POWER, PHENOLIC AND MINERAL COMPOSITION OF SANGUISORBA MINOR SCOP." In 1st International Symposium on Biotechnology. University of Kragujevac, Faculty of Agronomy, 2023. http://dx.doi.org/10.46793/sbt28.305dj.

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In this study, extracts of the aerial partsof Sanguisorba minorScop. wereanalysed for antioxidant activity, quantification of the total phenolic and flavonoid and bioaccumulation potential of heavy metals.The total phenols amounts was the highest at acetone´sextracts of root (117.27 mg GAE /g dry weight), stem and leaf (133.61 mg GAE /g dry weight ) and flower (116.77 mg GAE /g dry weight) and total flavonoids acetone´sextractsof flower (50.69 mg RU/g). The highest DPPH-scavenging capacity had flower methanol extract 7.08 (IC50 µg/ml). The plant accumulates large amounts of Zn, Ni and Cu in th
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Shaikh, Faiyaz, Shamal Talole, Sarwan Bradosty, and Raghavendra Hallur. "Biological Activity Assessment and GC–MS Screening of Phytoconstituents in Dentella repens Leaf Methanolic Extract." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1249.

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Context: Dentella repens (L.) J.R. Forst. &amp; G. Forst., a member of the Rubiaceae family, is renowned for its therapeutic properties. Aim: This research pursued to examine the phytoconstituents and assess the biological activities of the Dentella repens Leaf Methanolic Extract (DLME). Material and Methods: In vitro experiments were carried to evaluate its anti-inflammatory, anthelmintic, and antioxidant potential. Qualitative and quantitative analyses of phytochemicals, along with fingerprint analysis using gas chromatography and mass spectroscopy (GC-MS), were performed. Results: Our findi
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Barboza Rodolfo, S., MM Valente Ligia, T. Wolff, A. Miranda Iranaia, SL Neris Rômulo, and M. Gomes. "Major compounds of the anti-dengue active leaf methanol extracts from Faramea hyacinthina and Faramea truncata (Rubiaceae)." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608063.

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Janić, Marijana, Aleksandar Krstić, Ana Valenta Šobot, et al. "DIFFERENCE IN PHYTOCHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY SCREENING OF TWO METHANOLIC SAGE EXTRACTS." In 8th Workshop Food and Drug Safety and Qualit. Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, 2024. http://dx.doi.org/10.46793/8fdsq.pb3mj.

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Sage has been used in traditional medicine to prevent and treat many health problems. This study aimed to determine and compare the phytochemical composition and antioxidative activity of sage leaf extracts obtained with 50% methanol (50MSE) and 80% methanol (80MSE). We determined the total phenolic content (TPC), total tannin content (TTC), and total flavonoid content (TFC) in extracts. Terpenoids were identified using gas chromatography-mass spectrometry (GC–MS), and the radical scavenging capacity of extracts was measured using DPPH assay. TPC was higher in 80MSE, TTC was higher in 50MSE, a
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Jocić, Ana, Slađana Marić, Jasmina Mušović, Danijela Tekić, and Aleksandra Dimitrijević. "EFFICIENT REMOVAL OF DELTAMETHRIN AND CLOMAZONE FROM WATER USING IONIC LIQUID-BASED AQUEOUS BIPHASIC SYSTEMS." In 8th Workshop Food and Drug Safety and Qualit. Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, 2024. http://dx.doi.org/10.46793/8fdsq.pb4aj.

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Sage has been used in traditional medicine to prevent and treat many health problems. This study aimed to determine and compare the phytochemical composition and antioxidative activity of sage leaf extracts obtained with 50% methanol (50MSE) and 80% methanol (80MSE). We determined the total phenolic content (TPC), total tannin content (TTC), and total flavonoid content (TFC) in extracts. Terpenoids were identified using gas chromatography-mass spectrometry (GC–MS), and the radical scavenging capacity of extracts was measured using DPPH assay. TPC was higher in 80MSE, TTC was higher in 50MSE, a
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Nontasirichayakul, Chanicha, Chutima Wiranidchapong, Worapan Sithithaworn, and Duangratana Shuwisitkul. "Optimization of Formulation Variables Using Central Composite Design to Enhance Andrographolide Release from <i>Andrographis paniculata</i> Extract-Chitosan Solid Dispersion." In 5th International Conference and Exhibition on Pharmaceutical Sciences and Technology 2022. Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-3xj8r7.

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Andrographolide (AGP), a major component of Andrographis paniculata (Burm.f.) Nees (AP), has several biological activities. Nevertheless, poorly water solubility and low bioavailability of AGP lead to decrease clinical benefits. Therefore, this study aims to develop of AP extract-chitosan solid dispersion using central composite design (CCD) to enhance AGP release. AP crude extract was obtained by Soxhlet extractor using 85%v/v ethanol as a solvent extraction. Then, AP extract, chitosan, and poloxamer 188 in the concentrations provided by CCD was spray dried. The in-vitro release of AP extract
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