Academic literature on the topic 'MGIT-TB'

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Journal articles on the topic "MGIT-TB"

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Choerunisa, Towifah Fauziah, Leni Lismayanti, Tiene Rostini, Ryan Bayusantika, and Ida Parwati. "Comparison of Line Probe Assay (LPA) and Mycobacterium Growth Indicator Tubes (MGIT) Assay for Second-line TB Drug Susceptibility Testing." Indonesian Biomedical Journal 13, no. 3 (2021): 256–60. http://dx.doi.org/10.18585/inabj.v13i3.1521.

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BACKGROUND: Tuberculosis (TB) infection is one of the most prominent health issues in the world, including in Indonesia. TB is evolving into multidrug-resistant tuberculosis (MDR-TB) and requiring second-line TB drugs. Mycobacterium growth indicator tube (MGIT) is the gold standard for susceptibility testing of second-line TB drugs. Alternatively, line probe assay (LPA), which detects genes resistant to second-line TB drugs, takes a shorter time to run. This study aims to compare MGIT and LPA's ability to detect TB resistance to second-line TB drugs and observe mutation patterns of genes encod
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Tania, Tryna, Pratiwi Sudarmono, R. Lia Kusumawati, et al. "Whole-genome sequencing analysis of multidrug-resistant Mycobacterium tuberculosis from Java, Indonesia." Journal of Medical Microbiology 69, no. 7 (2020): 1013–19. http://dx.doi.org/10.1099/jmm.0.001221.

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Introduction. Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem globally, including in Indonesia. Whole-genome sequencing (WGS) analysis has rarely been used for the study of TB and MDR-TB in Indonesia. Aim. We evaluated the use of WGS for drug-susceptibility testing (DST) and to investigate the population structure of drug-resistant Mycobacterium tuberculosis in Java, Indonesia. Methodology. Thirty suspected MDR-TB isolates were subjected to MGIT 960 system (MGIT)-based DST and to WGS. Phylogenetic analysis was done using the WGS data. Results obtained using MGIT-base
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Zhao, Ping, Qin Yu, and Yu Zhang. "Evaluation of a manual identification system for detection of Mycobacterium tuberculosis in a primary tuberculosis laboratory in China." Journal of International Medical Research 47, no. 6 (2019): 2666–73. http://dx.doi.org/10.1177/0300060519844399.

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Objective To compare the diagnostic performance of the manual BACTEC™ Mycobacteria Growth Indicator Tube (MGIT™) system (M-MGIT) with the automated BACTEC™ MGIT™ 960 system (A-MGIT) and Löwenstein-Jensen (L-J) culture method in detecting mycobacteria in sputum specimens from patients with suspected pulmonary tuberculosis (TB). Methods For this cross-sectional study, sputum samples were taken from patients aged ≥18 years attending a TB clinic in Beijing, China between July 2015 and October 2016. Processed sputum samples were inoculated into the MGIT systems and L-J medium for up to 6 and 8 week
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Hanna, Bruce A., Adeleh Ebrahimzadeh, L. Bruce Elliott, et al. "Multicenter Evaluation of the BACTEC MGIT 960 System for Recovery of Mycobacteria." Journal of Clinical Microbiology 37, no. 3 (1999): 748–52. http://dx.doi.org/10.1128/jcm.37.3.748-752.1999.

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We evaluated the BACTEC MGIT 960 system, which is a fully automated, noninvasive system for the growth and detection of mycobacteria with a capacity to incubate and continuously monitor 960 7-ml culture tubes. We studied 3,330 specimens, 2,210 respiratory and 1,120 nonrespiratory specimens, collected from 2,346 patients treated at six sites. Processed specimens were inoculated into the BACTEC MGIT 960 and BACTEC 460 TB systems, as well as onto Lowenstein-Jensen slants and Middlebrook 7H11/7H11 selective plates. From all culture systems, a total of 362 isolates of mycobacteria were recovered; t
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Jorwal, Pankaj, Binit Kumar Singh, Ankita Anand, et al. "Diagnostics Evaluation of Smart Sure™ Mycobacterium tuberculosis Screening Kit and Smart Sure™ Multidrug-resistant Tuberculosis Detection Kit on Nonsputum Specimens at a Tertiary Care Center of North India." International Journal of Mycobacteriology 13, no. 3 (2024): 275–81. http://dx.doi.org/10.4103/ijmy.ijmy_140_24.

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Background: Tuberculosis (TB) is caused due to the infection of Mycobacterium tuberculosis (MTB) and it can infect the various parts of the human body. The disease is highly prevalent and is the second most common cause of death worldwide after COVID-19. Apart from sputum specimen, it is exceedingly difficult to diagnose due to its paucibacillary nature. The current study was intended to evaluate the accuracy of Smart Sure™ MTB and multidrug-resistant-TB (MDR-TB) kits (Genetix Biotech Asia Pvt. Ltd., India) with Xpert ultra and Mycobacterium growth indicator tube (MGIT) culture on nonsputum sp
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Makamure, Beauty, Salome Makumbirofa, Tsitsi Bandason, et al. "A suggested algorithm for detection of multi drug-resistant tuberculosis in Zimbabwe." Journal of Infection in Developing Countries 11, no. 08 (2017): 611–18. http://dx.doi.org/10.3855/jidc.8009.

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Introduction: Rapid genotypic and phenotypic methods for multi-drug-resistant-tuberculosis (MDR-TB) detection are now widely available. Zimbabwe adopted the use of GeneXpert-MTB/RIF, microscopic-observation-drug-susceptibility-assay (MODS) and Mycobacteria-Growth-Indicator-Tube (MGIT) drug-susceptibility-testing (DST). Data is limited on the ideal combination of use of these methods in resource limited settings.
 Methodology: Between August 2014 to July 2015, 211 sputa from MDR-TB suspects were tested with GeneXpert-MTB/RIF, MODS, manual-MGIT and Lowenstein-Jensen (LJ)-DST to determine di
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Rahman, S. M. Mazidur, Md Fahim Ather, Rumana Nasrin, et al. "Performance of WHO-Endorsed Rapid Tests for Detection of Susceptibility to First-Line Drugs in Patients with Pulmonary Tuberculosis in Bangladesh." Diagnostics 12, no. 2 (2022): 410. http://dx.doi.org/10.3390/diagnostics12020410.

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The fast and accurate detection of susceptibility in drugs is a major challenge for a successful tuberculosis (TB) control programme. This study evaluated the performance of WHO-endorsed rapid diagnostic tools, such as BACTEC MGIT 960 SIRE (MGIT SIRE), GenoType MTBDRplus (MTBDRplus) and Xpert MTB/RIF (Xpert), for detecting susceptibility to first-line anti-TB drugs among pulmonary TB patients in Bangladesh. A total of 825 sputum samples with results from drug susceptibility testing (DST) against first-line anti-TB drugs in the MGIT SIRE, MTBDRplus and Xpert assays were evaluated and compared w
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Rajani, Monika, and Molay Banerjee. "Evaluation of Various Diagnostic Techniques for the Diagnosis of Pulmonary and Extra Pulmonary Tuberculosis at a Tertiary Care Center in North India." Infectious Disorders - Drug Targets 20, no. 4 (2020): 433–39. http://dx.doi.org/10.2174/1871526519666191011165702.

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Introduction: Tuberculosis (TB) is a one of the main causes of mortality and morbidity worldwide. Bactec MGIT (Mycobacteria Growth Indicator Tube) system is a rapid, reliable automated system for early diagnosis of pulmonary and extra pulmonary TB in setups where purchase of expensive instruments is not possible. The present study was thus carried out to evaluate AFB microscopy, culture on Lowenstein Jensen media and micro MGIT system for early and accurate diagnosis of Tuberculosis. Methods: A total of 280 samples were processed for direct AFB smear examination, and culture on micro MGIT and
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Vater, Maria Claudia, Mário Motta Maximo, Adriana da Silva Rezende Moreira, Suely Conceição Alves da Silva, Isabela Neves de Almeida, and Afrânio Lineu Kritski. "Cost Analysis for Patients with Presumed Pulmonary Tuberculosis Attended in the Public Health System of Rio de Janeiro, Brazil." International Journal of Mycobacteriology 10, no. 2 (2021): 136–41. http://dx.doi.org/10.4103/ijmy.ijmy_58_21.

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Background: In last years, few attention has given to the patient's prediagnostic costs when evaluating the introduction of new technologies for tuberculosis (TB) and in this context, this study evaluated patient's costs and cost-effectiveness incurred with TB diagnosis comparing BactecTMMGITTM960 system (MGIT) to the Löwestein–Jensen (LJ) culture in a health center and in a university hospital, in Rio de Janeiro City, Brazil. Methods: Patient's mean costs were evaluated during the diagnosis process and cost-effectiveness based on mean time in days for the adoption of appropriate clinical anti
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Mittal, Vineeta, Manoj Kumar, and Ajay Kumar Singh. "TB LAMP assay, a beneficial tool for the diagnosis of Tubercular meningitis in resource-limited settings." Journal of Infection in Developing Countries 18, no. 03 (2024): 435–40. http://dx.doi.org/10.3855/jidc.18115.

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Introduction: Tubercular meningitis (TBM) is a serious public health problem in developing countries as it leads to significant mortality and residual neurological sequelae. The estimated mortality due to TBM in India is 1.5 per 100,000 population. In resource-limited settings, only the Ziehl-Neelsen (ZN) stain, which has very little sensitivity, is available. The World Health Organization recommended the Loop Mediated Isothermal Amplification (TB LAMP) assay for pulmonary tuberculosis only. We evaluated this test for tubercular meningitis as well. Methodology: In a cross-sectional study of 2-
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Conference papers on the topic "MGIT-TB"

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Mansoor, H., N. Hirani, VV Chavan, et al. "Clinical utility of target-based next-generation sequencing for drug-resistant tuberculosis: a pilot from Mumbai, India." In MSF Scientific Days International 2022. MSF-USA, 2022. http://dx.doi.org/10.57740/atfq-6s03.

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INTRODUCTION In countries with a high tuberculosis (TB) burden, poor access to drug susceptibility testing is a major bottleneck in diagnosing drug-resistant (DR) TB. India is estimated to account for a quarter of multidrug-resistant (MDR)-TB patients globally, with around 124,000 cases in 2020. Mumbai, a densely populated city in Maharashtra State, is a DR-TB hotspot with 24% of treatment- naïve cases, and 41% of previously-treated cases, having MDR-TB, and a high frequency of fluoroquinolone resistance occurring among these MDR-TB cases. Targeted next- generation sequencing (tNGS) is a promi
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Narute, Sunil, Kapil Salgia, Pratibha Singhal, and Vipul Kalley. "Comparative study of gene Xpert MTB/RIF, smear microscopy and TB MGIT culture in diagnosis of tuberculosis in India." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa1533.

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Журило, О. А., О. В. Чернов, А. І. Барбова, П. С. Трофімова та П. С. Миронченко. "Порівняльний аналіз результатів ТМЧ до ПТП І та ІІ ряду, отриманих методом цСНП і молекулярно-генетичним методом із застосуванням картриджів Xpert MBTRif/Ultra та Xpert MBT/XDR". У Міжнародна науково-практична конференція, присвячена Всесвітньому дню здоров’я: «Інноваційні підходи до діагностики, лікування туберкульозу та інших захворювань легень: практичні рекомендації для лікарів загальної практики, фтизіатрів і пульмонологів» 7 квітня 2025 року (онлайн), м. Київ, Україна. Національний науковий центр фтизіатрії, пульмонології та алергології імені Ф.Г. Яновського, 2025. https://doi.org/10.32902/2663-0338-2025-1s-04.

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Обґрунтування. Цільове секвенування наступного покоління (цСНП) – сучасна молекулярно-генетична технологія для виявлення всього спектра мутацій ДНК Mycobacterium tuberculosis (МБТ), а серед них і клінічно значущих, що є основою для своєчасного призначення ефективних схем лікування хворих на туберкульоз (ТБ) та моніторингу специфічної терапії кожного випадку захворювання. Мета. Провести порівняльний аналіз результатів генетичного тесту медикаментозної чутливості (гТМЧ) МБТ, отриманих методом цСНП, з результатами фенотипового ТМЧ (фТМЧ) у рідкому середовищі в системі ВАСТЕС 960 MGIT. Матеріали т
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