Academic literature on the topic 'Microangiopathic Anemia'

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Journal articles on the topic "Microangiopathic Anemia"

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Brocklebank, Vicky, Katrina M. Wood, and David Kavanagh. "Thrombotic Microangiopathy and the Kidney." Clinical Journal of the American Society of Nephrology 13, no. 2 (2017): 300–317. http://dx.doi.org/10.2215/cjn.00620117.

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Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases, effective specific treatment can result in good outcomes. This review considers the classification, pathology, epidemiology, characteristics, and pathogenesis of the thrombotic microangiopathies, and outlines a pragmatic approach to diagnosis and
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Bhawna, Gondwal. "Thrombotic Microangiopathic Haemolytic Anaemia: A Pathologic Abnormality Associated with Diverse Clinical Syndromes." British Journal of BioMedical Research 1, no. 4 (2017): 217–22. https://doi.org/10.24942/bjbmr.2017.165.

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A pathological process of microvascular thrombosis, microangiopathic hemolytic anemia and thrombocytopenia, with ischemia and infraction, affecting particularly kidney and brain is Thrombotic microangiopathy  (TMA). Disseminated intravascular coagulation (DIC) is caused by severe infectious disease and systemic inflammatory syndrome (SIRS). Thrombotic microangiopathy  (TMA) a rare but devastating disease, also known as microangiopathic hemolytic anemia (MAHA) in combination with thrombocytopenia and signs of organ damage. These pathological features are included in different clinical
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Todorović, Željko, and Marko Anđelić. "Thrombotic microangiopathy as the first manifestation of disseminated malignant disease." Srpski medicinski casopis Lekarske komore 3, no. 4 (2022): 492–98. http://dx.doi.org/10.5937/smclk3-40946.

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Introduction: Thrombotic microangiopathies are a group of diseases characterized by disseminated intravascular thrombosis, thrombocytopenia and ischemic organ damage. This group includes thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome. One of the causes of thrombotic microangiopathy, although rare, can also be malignant diseases, primarily cancers of the stomach, prostate, breast and lungs. Case report: We present a patient with thrombotic microangiopathy and disseminated malignant disease of unclear etiology. Conclusion: This clinical entity is called carcinoma-associated th
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Ikushima, Eigo, Manabu Hisahara, Takuya Nishijima, et al. "Atypical Hemolytic Uremic Syndrome following Acute Type A Aortic Dissection." Case Reports in Hematology 2020 (March 4, 2020): 1–4. http://dx.doi.org/10.1155/2020/2467953.

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Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA)-related disease that manifests as a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI) and is caused by uncontrolled activation of the complement system. We report the case of a 61-year-old woman with acute type A aortic dissection that subsequently developed into aHUS. The hematologic disorders underlying aHUS improved after treatment with the complement inhibitor eculizumab. It is important to consider aHUS when a patient clinically develops a triad of microangiopathic hem
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Wasekar, Nilesh, and Shivani Joshi. "Interesting cases of microangiopathic hemolytic anemia." Medicover Journal of Medicine 1, no. 4 (2024): 172–75. https://doi.org/10.4103/mjm.mjm_38_24.

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Microangiopathic hemolytic anemia (MAHA) is a type of hemolytic anemia where there is fragmentation and hemolysis due to damage of erythrocytes in the small blood vessels. The initial evaluation is focused on confirming MAHA and thrombocytopenia and excluding systemic disorders that manifest these findings/mimic thrombotic thrombocytopenic purpura. All patients with a suspected primary thrombotic microangiopathy should have a thorough laboratory workup. ADAMTS13 activity is measured before starting therapeutic plasma exchange (TPE). The immediate management decision is whether to perform TPE o
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Lee, Eric H., Salman Otoukesh, Amir Abdi pour, and Gayathri Nagaraj. "Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia." Case Reports in Oncology 12, no. 1 (2019): 104–8. http://dx.doi.org/10.1159/000494753.

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Hemolytic anemia in the setting of malignancy is a rare manifestation of paraneoplastic syndrome with significant morbidity. Here we discuss a case involving metastatic breast cancer presenting with severe hemolytic anemia and renal failure secondary to thrombotic microangiopathy of malignancy. This case discusses the workup for secondary hemolytic anemia, a possible role for therapeutic plasma exchange in this setting, as well the current understanding of the management of microangiopathic hemolytic anemia of malignancy.
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Tulai, Iulia M., Oana M. Penciu, Raymond Raut, and Alla Rudinskaya. "Catastrophic Antiphospholipid Syndrome Presenting as Congestive Heart Failure in a Patient with Thrombotic Microangiopathy." Texas Heart Institute Journal 46, no. 1 (2019): 48–52. http://dx.doi.org/10.14503/thij-17-6472.

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Thrombotic microangiopathic syndromes are characterized by thrombus formation leading to microangiopathic hemolytic anemia, thrombocytopenia, and end-organ injury that most often affects the kidney and brain. Patients with thrombotic microangiopathy can also present with cardiac involvement, which has been shown to worsen their prognosis. We describe the case of a 46-year-old woman who presented with acute congestive heart failure as a manifestation of catastrophic antiphospholipid syndrome, which is characterized by rapidly progressing multiorgan involvement. Targeted therapy improved our pat
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Skwierawska, Kamila, Krzysztof Woźniak, Anna Waszczuk-Gajda, et al. "Cancer-related microagiopathic hemolytic anemia in a patient with breast cancer – diagnostic difficulties." OncoReview 10, no. 4(40) (2020): 134–38. http://dx.doi.org/10.24292/01.or.420231220.

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Cancer-related microangiopathic hemolytic anemia is rarely recognized as a paraneoplastic syndrome with a very poor prognosis in cancer patients. The treatment and prognosis are significantly different from that in other thrombotic microangiopathies, such as thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. The case of described patient demonstrates the diagnostic difficulties in diagnosing the causes of hemolytic anemia in patient with breast cancer and appropriate treatment.
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Özsoylu, Şinasi. "About Microangiopathic Hemolytic Anemia." Turkish Journal of Hematology 32, no. 1 (2015): 92. http://dx.doi.org/10.4274/tjh.2014.0382.

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Morton, Jordan M., and James N. George. "Microangiopathic Hemolytic Anemia and Thrombocytopenia in Patients With Cancer." Journal of Oncology Practice 12, no. 6 (2016): 523–30. http://dx.doi.org/10.1200/jop.2016.012096.

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The unexpected occurrence of thrombotic microangiopathy (TMA), characterized by microangiopathic hemolytic anemia and thrombocytopenia, in a patient with cancer requires urgent diagnosis and appropriate management. TMA is a term used to describe multiple syndromes caused by microvascular thrombosis, including thrombotic thrombocytopenic purpura (TTP), Shiga toxin–mediated hemolytic uremic syndrome, and complement-mediated TMA. In patients with cancer, systemic microvascular metastases and bone marrow involvement can cause microangiopathic hemolytic anemia and thrombocytopenia. This occurs most
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Dissertations / Theses on the topic "Microangiopathic Anemia"

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PIHAN, ISABELLE. "Anemie hemolytique microangiopathique dans les cancers : a propos de neuf observations avec revue de la litterature." Amiens, 1989. http://www.theses.fr/1989AMIEM072.

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LE, GUELTE ANNE. "L'anemie hemolytique par microangiopathie dans les tumeurs solides de l'adulte." Lyon 1, 1989. http://www.theses.fr/1989LYO1M368.

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BAUZA, FRANCOISE. "Reflexions sur le hellp syndrome." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20201.

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Chao, Shih-Hsuan, and 趙師萱. "Efficacy and Safety of Rituximab in Autoimmune and Microangiopathic Hemolytic Anemia: A Systematic Review and Meta-analysis." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/xp9h5e.

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碩士<br>國立陽明大學<br>藥理學研究所<br>107<br>Background: Hemolytic anemia (HA) is a kind of anemia due to the destruction of red blood cells (RBC) from the circulation before their normal life span. Location of RBC destruction occurs varied, such as in larger vessels (eg. autoimmune hemolytic anemia, AIHA) or smaller vessels (eg. microangiopathic hemolytic anemia, MAHA). AIHA is a rare disease caused by autoantibodies directed against erythrocyte self-antigens, and its thermal-based classification is based on the optimal autoantibody-RBC reactivity temperature. MAHA is non-immune hemolysis resulting from
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Book chapters on the topic "Microangiopathic Anemia"

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Gupta, Arun. "Microangiopathic Hemolytic Anemia." In Decision Making Through Problem Based Learning in Hematology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-8933-1_15.

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Nahid, Seema, Fateen Shareef, Azha Fatima, Umm E. Amara, Umme Nashrah, and Ifrah Fatima. "Microangiopathic Hemolytic Anemia of Pregnancy: Facts and Figures." In Updates in Intensive Care of OBGY Patients. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9577-6_2.

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Singh, Aakanksha, and Mrinalini Kotru. "Laboratory Diagnosis of Microangiopathic Hemolytic Anemia Including TTP, DIC, and HUS." In Hematopathology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7713-6_7.

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Mallouh, Ahmad A. "Microangiopathic Hemolytic Anemias." In Textbook of Clinical Pediatrics. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02202-9_323.

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Shenkman, Boris, Yulia Einav, and Ophira Salomon. "Thrombotic Thrombocytopenic Purpura and Other Thrombotic Microangiopathic Hemolytic Anemias." In Diagnostic Criteria in Autoimmune Diseases. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-285-8_101.

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Shenkman, Boris, Yulia Einav, Ophira Salomon, Yehuda Shoenfeld, Rocio Morán Contla, and Abihai Lucas Hernández. "Thrombotic Thrombocytopenic Purpura and Other Thrombotic Microangiopathic Hemolytic Anemias." In Autoimmune Disease Diagnosis. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-69895-8_109.

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"Microangiopathic Hemolytic Anemia." In Diagnostic Pathology: Blood and Bone Marrow. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-323-39254-9.50018-0.

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Tsai, H. M. "Microangiopathic Hemolytic Anemia." In Reference Module in Biomedical Sciences. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-801238-3.00069-6.

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"Microangiopathic Hemolytic Anemia." In Dictionary of Toxicology. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9283-6_1735.

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Kaufman, Lewis. "Thrombotic Microangiopathies." In Kidney Protection, edited by Vijay Lapsia, Bernard G. Jaar, and A. Ahsan Ejaz. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190611620.003.0032.

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The thrombotic microangioapathy (TMA) syndromes are characterized by concomitant occurrence of severe thrombocytopenia, microangiopathic hemolytic anemia, and ischemic end organ dysfunction often of the kidneys. While several of their features overlap in terms of clinical presentation, the pathophysiology and underlying causes of each form of primary TMA are quite unique. Over the last decade, researchers’ understanding of these underlying causes has accelerated dramatically, providing transformative approaches to the way patients with these disorders are diagnosed, followed, stratified, and t
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Conference papers on the topic "Microangiopathic Anemia"

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Bedient, Timothy J., and Edward C. Dempsey. "Microangiopathic Hemolytic Anemia From Occult Adenocarcinoma." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4608.

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Santos, João Vitor Ribeiro dos, Mariana Spitz, and Ana Carolina Andorinho. "Stroke secondary to thrombotic microangiopathy." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.300.

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Introduction: Thrombotic thrombocytopenic purpura (TTP) is a hematological disease resulting from the ADAMTS 13 plasmatic protein deficit. It can be congenital or sporadic, and is usually autoimmune. Pathological platelet adhesion occurs, leading to microthrombi in capillary and arterial circulation, microangiopathic anemia and ischemia. The clinical picture includes thrombocytopenia, renal dysfunction, fluctuating neurological symptoms, microangiopathic hemolytic anemia, and fever. Methods: Case report of a 51-year-old male hypertensive patient, diagnosed with idiopathic thrombocytopenic purp
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Biegelmeyer, Erika, Julia Boechat Farani, Evelise Mileski do Amaral Berlet, Marcel Mathias Villaça, Marília Voges de Souza, and Cristina Ferreira Rabelo. "Intestinal vasculitis, mesenteritis, microangiopathic anemia and alveolar hemorrhage: a severe presentation of dermatomyositis." In SBR 2021 Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2021. http://dx.doi.org/10.47660/cbr.2021.2089.

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Lim, Brian F., Andrew Caravello, James A. Espinosa, and Alan Lucerna. "Case Report: A Case of TTP in the ED." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.64_2024.

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We report a case of a 54-year-old female who presented with mild shortness of breath, lower chest discomfort, fatigue, and weakness ongoing for several days and was diagnosed with thrombotic thrombocytopenic purpura (TTP). TTP is characterized by microangiopathic hemolytic anemia and thrombocytopenia due to either an inherited or immune-mediated reduction in von Willebrand Factor (VWF) cleaving protease ADAMTS13. Patients presenting with non-specific symptoms is becoming increasingly common and initial bias could be to attribute symptoms to viral syndrome or upper respiratory tract infection.
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