Academic literature on the topic 'Microbiota imbalance'

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Journal articles on the topic "Microbiota imbalance"

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Liu, Qihong, Yunfeng Luo, and Xiao Ke. "Interaction between the Gut Microbiota and Intestinal Motility." Evidence-Based Complementary and Alternative Medicine 2022 (November 15, 2022): 1–5. http://dx.doi.org/10.1155/2022/3240573.

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The gut microbiota is the largest symbiotic ecosystem with the host and has been proven to play an important role in maintaining the stability of the intestinal environment. The imbalance of the gut microbiota is caused by the imbalance between the symbiotic microbiota and the pathogenic microbiota. The commensal microbiome regulates intestinal motility, while the pathogenic microbiome causes intestinal motility disorder, resulting in disease development. Intestinal motility is a relatively general term, and its meaning may include intestinal muscle contraction, intestinal wall biomechanics, i
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Wei, Mingbang, Huaizhi Liu, Yu Wang, Mingyang Sun, and Peng Shang. "Mechanisms of Male Reproductive Sterility Triggered by Dysbiosis of Intestinal Microorganisms." Life 14, no. 6 (2024): 694. http://dx.doi.org/10.3390/life14060694.

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Abstract: The intestinal microbiota, comprised of bacteria, archaea, and phages, inhabits the gastrointestinal tract of the organism. Male reproductive sterility is currently a prominent topic in medical research. Increasing research suggests that gut microbiota dysbiosis can result in various reproductive health problems. This article specifically investigates the impact of gut microbiota dysbiosis on male reproductive infertility development. Gut microbiota imbalances can disrupt the immune system and immune cell metabolism, affecting testicular growth and sperm production. This dysfunction
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Origüela, Valentina, and Alvaro Lopez-Zaplana. "Gut Microbiota: An Immersion in Dysbiosis, Associated Pathologies, and Probiotics." Microorganisms 13, no. 5 (2025): 1084. https://doi.org/10.3390/microorganisms13051084.

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The importance of the microbiome, particularly the gut microbiota and its implications for health, is well established. However, an increasing number of studies further strengthen the link between an imbalanced gut microbiota and a greater predisposition to different diseases. The gut microbiota constitutes a fundamental ecosystem for maintaining human health. Its alteration, known as dysbiosis, is associated with a wide range of conditions, including intestinal, metabolic, immunological, or neurological pathologies, among others. In recent years, there has been a substantial increase in knowl
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Khamrokulovich, Babakulov Sharof. "CHANGES IN THE COMPOSITION OF GUINEA PIG SALIVA DURING MICROBIOTA IMBALANCE." American Journal Of Biomedical Science & Pharmaceutical Innovation 4, no. 12 (2024): 18–21. https://doi.org/10.37547/ajbspi/volume04issue12-04.

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This article investigates the biochemical characteristics of guinea pig saliva under conditions of dysbiosis. Dysbiosis, which represents a disruption of normal microbiota, can significantly impact the health of animals and their physiological processes. In the course of the experiment, key components of saliva, including proteins, carbohydrates, and electrolytes, were analyzed to identify changes associated with microbiota imbalance. The results showed significant deviations in the biochemical composition of guinea pig saliva, indicating potential mechanisms by which dysbiosis affects digesti
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Tîrziu, Andreea-Talida, Monica Susan, Razvan Susan, et al. "From Gut to Eye: Exploring the Role of Microbiome Imbalance in Ocular Diseases." Journal of Clinical Medicine 13, no. 18 (2024): 5611. http://dx.doi.org/10.3390/jcm13185611.

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Background: The gut microbiome plays a crucial role in human health, and recent research has highlighted its potential impact on ocular health through the gut–eye axis. Dysbiosis, or an imbalance in the gut microbiota, has been implicated in various ocular diseases. Methods: A comprehensive literature search was conducted using relevant keywords in major electronic databases, prioritizing recent peer-reviewed articles published in English. Results: The gut microbiota influences ocular health through immune modulation, maintenance of the blood–retinal barrier, and production of beneficial metab
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Fernandes, Camila, Mahara Coelho Crisostomo Miranda, Cássia Rodrigues Roque, et al. "Is There an Interplay between Environmental Factors, Microbiota Imbalance, and Cancer Chemotherapy-Associated Intestinal Mucositis?" Pharmaceuticals 17, no. 8 (2024): 1020. http://dx.doi.org/10.3390/ph17081020.

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Interindividual variation in drug efficacy and toxicity is a significant problem, potentially leading to adverse clinical and economic public health outcomes. While pharmacogenetics and pharmacogenomics have long been considered the primary causes of such heterogeneous responses, pharmacomicrobiomics has recently gained attention. The microbiome, a community of microorganisms living in or on the human body, is a critical determinant of drug response and toxicity. Factors such as diet, lifestyle, exposure to xenobiotics, antibiotics use, illness, and genetics can influence the composition of th
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Gagnière, Johan. "Gut microbiota imbalance and colorectal cancer." World Journal of Gastroenterology 22, no. 2 (2016): 501. http://dx.doi.org/10.3748/wjg.v22.i2.501.

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Pires, Lara, Ana M. González-Paramás, Sandrina A. Heleno, and Ricardo C. Calhelha. "Exploring Therapeutic Advances: A Comprehensive Review of Intestinal Microbiota Modulators." Antibiotics 13, no. 8 (2024): 720. http://dx.doi.org/10.3390/antibiotics13080720.

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The gut microbiota establishes a mutually beneficial relationship with the host starting from birth, impacting diverse metabolic and immunological processes. Dysbiosis, characterized by an imbalance of microorganisms, is linked to numerous medical conditions, including gastrointestinal disorders, cardiovascular diseases, and autoimmune disorders. This imbalance promotes the proliferation of toxin-producing bacteria, disrupts the host’s equilibrium, and initiates inflammation. Genetic factors, dietary choices, and drug use can modify the gut microbiota. However, there is optimism. Several thera
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Volynets, Galina V., A. I. Khavkin, T. A. Skvortsova, A. V. Nikitin, and V. V. Matkash. "DISEASES OF THE LIVER AND INTESTINAL MICROBIOME." Russian Pediatric Journal 21, no. 6 (2019): 366–77. http://dx.doi.org/10.18821/1560-9561-2018-21-6-366-377.

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The review presents data on the effect of the intestinal microbiota on the regulation of the synthesis and metabolism of bile acids. Violations of the bile acid pool have been shown to be accompanied by an imbalance of the intestinal microbiota, which can determine the dynamics of the formation of cholestatic liver diseases and their progression up to cirrhosis of the liver. Impaired bile acid synthesis is often caused by an imbalance in the intestinal microbiome. Changes in the complex connections of the intestinal microbiome and the metabolism of bile acids influence the formation of liver a
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Izmailovich, M. R., O. Y. Dedova, B. S. Koshkarbayeva, et al. "Liver Dysfunction and Microbiome Imbalance: Their Role in the Development of Allergic Reactions." Juvenis Scientia 11, no. 2 (2025): 21–32. https://doi.org/10.32415/jscientia_2025_11_2_21-32.

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Over the past decades, there has been a significant increase in the prevalence of allergic diseases, attributed to multiple factors, including liver dysfunction and gut microbiome imbalance. The liver plays a central role in allergen detoxification, immune response regulation, metabolism of inflammatory mediators, and maintenance of immune tolerance. Impairment of liver function can lead to the accumulation of toxins and metabolic byproducts, contributing to hypersensitivity and inflammatory processes. On the other hand, the gut microbiota actively participates in immune homeostasis and the de
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Dissertations / Theses on the topic "Microbiota imbalance"

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Звягіна, Н. Ю. "Вивчення терапевтичних підходів реабілітації піхвового вмісту у жінок, що перенесли запальні захворювання статевих органів з використанням пробіотиків". Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/36426.

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Сучасні підходи до лікування захворювань органів малого тазу (ЗЗОМТ) базуються на використанні антибіотиків різноманітних груп, які разом із боротьбою з запаленням викликають значні порушення в біоценозі статевих шляхів у жінок, що потребує подальшого поновлення нормальних співвідношень мікроорганізмів слизової піхви. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/36426
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Books on the topic "Microbiota imbalance"

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Moise, Ana Maria R. The Gut Microbiome. Greenwood, 2017. http://dx.doi.org/10.5040/9798400660849.

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This accessibly written, comprehensive summary of research findings on the gut microbiome and its implications for health and disease–a topic of growing interest and concern–serves as an essential resource for teachers and students. Most people know that the digestive tract contains billions of helpful gut bacteria, but how does the gut microbiome affect our health? What exactly do these bacteria do, and what are the negative effects when these microorganisms are harmed by what we eat and do? What impacts might they have on conditions such as irritable bowel syndrome (IBS), obesity, and autism
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Muñoz, George E., and Isabella Leoni Garcia. Functional Medicine Approach to Addiction. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0018.

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The functional medicine protocol complements and enhances the traditional approach to recovery. Seen from a functional medicine perspective, the path to substance/and or food addiction recovery involves a multimodal approach. It shifts the focus from the imbalances in the brain and neurotransmitters to treat the whole person. It does so by considering the metabolic, hormonal, psychologic, immunologic, and neurologic functions that have been disturbed by addiction and that further perpetuate the inflammatory state of active addiction and during recovery phases. The gut-brain axis is reviewed fr
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Gut Health: Education for Patients and the Public. Exon Publications, 2025. https://doi.org/10.36255/gut-health.

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Gut Health: Education for Patients and the Public Gut health plays a crucial role in digestion, immunity, and overall well-being. This article provides a comprehensive guide to understanding how the gut functions, the importance of the gut microbiome, and how lifestyle choices affect digestive health. It covers scientifically backed information on maintaining a healthy gut through diet, probiotics, prebiotics, and lifestyle adjustments while also addressing common digestive disorders and their causes. The article begins with an introduction to gut health, explaining why it matters and how it i
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Book chapters on the topic "Microbiota imbalance"

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Ragbetli, Murat Cetin, and Seda Keskin. "A Current Review on Diabetes Mellitus Induced Gut Microbiota and Histological Changes." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.2.

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Recent studies have highlighted the intricate relationship between diabetes mellitus (DM) and alterations in gut microbiota composition, as well as associated histological changes. Dysbiosis, characterized by an imbalance in microbial communities, has been observed in diabetic individuals, with decreased microbial diversity and altered abundance of specific taxa such as Firmicutes and Bacteroidetes. These changes are implicated in promoting systemic inflammation, insulin resistance, and metabolic dysfunction. Concurrently, diabetic conditions influence gut barrier integrity and mucosal immunit
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Shenderov, Boris A., Alexander V. Sinitsa, Mikhail M. Zakharchenko, and Christine Lang. "Factors and Agents that Modify the Composition and Functions of Symbiotic Microbiota; Diagnostic Methods for Microecological Imbalance and its Consequences." In METABIOTICS. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-34167-1_6.

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Kolla, Harish Babu, Prakash Narayana Reddy, and Pallaval Veera Bramhachari. "Dynamics of Respiratory Microbiome Profiles Contributes to Imbalance and Lung Dysbiosis in the Respiratory Tract." In Microbiome in Human Health and Disease. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3156-6_7.

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Chatterjee, Prity, Riya Dey, Shweta Kumari, Shreetama Mukherjee, Sumana Roy Chowdhury, and Krishnendu Adhikary. "A NARRATIVE OVERVIEW ON CRUCIAL ROLE OF GUT MICROBES IN CHRONIC INFECTIOUS AND INFLAMMATORY DISEASES." In Futuristic Trends in Medical Sciences Volume 3 Book 18. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bbms18p1ch8.

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Numerous microorganisms in the human gut microbiota fight pathogens in infectious diseases and suppress or induce inflammation in various immunological situations. A significant microbial community that is vital to human existence is the human gut microbiome. It promotes the proliferation, development, and differentiation of epithelial and immunological cells, which aids in maintaining intestinal homeostasis. Disorders that affect the microbiota induce an imbalance in the host’s & #39; immunological regulation. Research analysis suggests that the gut microbial ecology is linked to the onse
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Vakili, Bahareh, Parisa Shoaei, Zahra Esfandiari, and Seyed Davar Siadat. "Gut Microbiota and Inflammatory Bowel Disease." In Effect of microbiota on Health and disease [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105842.

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Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disorder that includes Crohn’s disease and ulcerative colitis. Ulcerative colitis involves the distal colon, proximal colon, and cecum and can lead to ulcerations and bleeding. Crohn’s disease appears as patched lesions in the gastrointestinal tract and inflammation, stenosis, or fistulas. IBD affects millions of people worldwide and has been associated with high morbidity and mortality. Our intestine is colonized by trillions of microorganisms (including bacteria, viruses, fungi, and protozoa), which constitutes the micr
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Toledo, Gustavo Honório, Camila Belfort Piantino Faria, Pedro Henrique Goveia Prudêncio, and Breno Henrique Ferreira Faria. "Defensing intestinal dysbiosis in obesity: Exploring the phyla Bacteroidetes and Firmicutes and the role of LPS endotoxin." In Themes focused on interdisciplinarity and sustainable development worldwide V. 02. Seven Editora, 2024. http://dx.doi.org/10.56238/sevened2024.002-075.

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Introduction: Obesity is a complex metabolic disorder influenced by genetic and environmental factors. Individuals with a body mass index (BMI) of 30 or greater are considered obese, but even being overweight (BMI between 25 and 29.9) can have adverse consequences. In Brazil, about 60% of adults were overweight in 2020, indicating a growing concern. In addition to physical transformations, obesity is associated with conditions such as insulin resistance, dyslipidemia, and systemic inflammation, increasing the risk of cardiovascular disease and cancer. Dysbiosis in the gut microbiota, an imbala
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Toledo, Gustavo Honório, Camila Belfort Piantino Faria, Pedro Henrique Goveia Prudêncio, and Breno Henrique Ferreira Faria. "Defensing intestinal dysbiosis in obesity: Exploring the phyla Bacteroidetes and Firmicutes and the role of LPS endotoxin." In Themes focused on interdisciplinarity and sustainable development worldwide V. 02. Seven Editora, 2024. http://dx.doi.org/10.56238/sevened2024.003-075.

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Introduction: Obesity is a complex metabolic disorder influenced by genetic and environmental factors. Individuals with a body mass index (BMI) of 30 or greater are considered obese, but even being overweight (BMI between 25 and 29.9) can have adverse consequences. In Brazil, about 60% of adults were overweight in 2020, indicating a growing concern. In addition to physical transformations, obesity is associated with conditions such as insulin resistance, dyslipidemia, and systemic inflammation, increasing the risk of cardiovascular disease and cancer. Dysbiosis in the gut microbiota, an imbala
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AlQutub, Russul, Reem El Asmar, and Dimitrios Papandreou. "Vitamin D, Immunity, and Gut Health." In Vitamin D-A Novel Therapy for Chronic Diseases? BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815305333124010005.

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The gut microbiota, a complex bacterial community within the gastrointestinal system, critically regulates human physiology. This article explores the complex interactions between the gut microbiota and vitamin D, impacting immunity and overall health. Vitamin D plays a role in immunological modulation, cell proliferation, and maintaining intestinal balance highlighting the intricate connections between gut microbiota and vitamin D in the gastrointestinal system. Recent research indicates that vitamin D receptors in the gastrointestinal tract may influence the gut microbiota's composition. Dys
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Priyamvada, Priyamvada. "Dysbiosis in Microbiome Leading to Colitis-Associated Cancer." In Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-3580-6.ch007.

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Colitis-associated cancers are a metastatic form of inflammatory bowel disease considered a vital health associated risk factor causing the death of approximately five lacs people every year throughout the world. There are trillions of bacteria that are associated with our gut as a part of our healthy microbiome. The microbiota plays a plethora of important role in determining the normal physiological processes of the cells and, subsequently, the body. The imbalance in microbiome diversity (dysbiosis) due to abnormal dietary habitats, hectic lifestyle, and other factors thus alters the normal
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Urganci, Ünkan. "Celiac Disease and Gut Microbiota: Herbal Treatment and Gluten-Free Diet." In Herbal Medicine for Autoimmune Diseases. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815305005124010011.

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Celiac disease (CD) manifests as a targeted autoimmune response that adversely affects the small intestine, primarily affecting individuals with a particular genetic predisposition. Diagnosis centers on identifying this gluten-sensitive enteropathy, which can be ameliorated through the implementation of a gluten-free diet (GFD), correlating with mucosal healing and symptom alleviation. The human microbiota, a vast symbiotic community within the gastrointestinal tract, profoundly impacts human health. Advances in genome sequencing have elucidated the intricate relationship between gut microbiot
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Conference papers on the topic "Microbiota imbalance"

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Skok, Pavel. "Is the repair of microbiotic imbalance the beginning of the story of cardiorenal protection?" In 7 th International Congress of Cardionephrology - KARNEF 2025. Punta Niš, 2025. https://doi.org/10.46793/karnef25.088s.

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The human microbiota is a community of bacteria, archaea, fungi, viruses and parasites that form an ecosystem consisting of approximately 1014 microorganisms. The diversity of this community is due to differences in the host’s genome and the influence of environmental factors, including hygiene, diet, lifestyle and the use of various drugs. Research work in the recent past has confirmed that the altered composition of the gut microbiota, dysbiosis, contributes to the development of various diseases, including cardiovascular, type 2 diabetes, chronic kidney disease, metabolic dysfunction-associ
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Орлина, Маргарита Анатольевна, Алёна Алексеевна Голубева, Татьяна Николаевна Земборская, Виктория Алексеевна Ломовцева, and Валерия Александровна Фрицлер. "SKIN MICROBIOTA IN PSORIASIS." In Инновационные исследования в современном мире: сборник статей международной научной конференции (Санкт-Петербург, Апрель 2024). Crossref, 2024. http://dx.doi.org/10.58351/240420.2024.24.60.002.

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Микробиома кожи представляет собой сложную экосистему, включающую в себя различные виды микроорганизмов, которые взаимодействуют не только друг с другом, но и с окружающей средой, включая эпителиальные и иммунные клетки хозяина. Эти взаимодействия играют ключевую роль в поддержании здоровья кожи, усиливая ее барьерные функции. Однако, как и в любой сложной системе, существует риск дисбаланса. Резидентные микробы кожи могут вести себя по-разному в зависимости от изменений в окружающей среде и состоянии хозяина. Таким образом, данное научное исследование рассматривает роль микробиомы кожи в пато
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Nogueira, Fábio Dias, Ana Klara Rodrigues Alves, Barbara Beatriz Lira da Silva, et al. "The autistic spectrum disorder and its relation to intestinal dysbiosis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.283.

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Introduction: Autistic Spectrum Disorder (ASD) is characterized by a neurodevelopmental disorder, in which the child has persistent deficits in verbal and / or non-verbal communication, social interaction and behavior. One of the factors related to the cause of ASD are nutritional aspects, such as intestinal dysbiosis. Objective: To analyze the relationship between imbalance in the intestinal microbiota and the pathophysiological characteristics of ASD. Methodology: This is a systematic review, carried out in the Pubmed, SciELO databases, in order to answer the question: what is the relationsh
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Marques, Ketlyn Miranda, Julia Saraiva Rocha, Natália Rocha de Almeida, et al. "Vaginosis and female intimate health: A study in Manhuaçu (MG)." In V Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvmulti2024-071.

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The anatomy of the female genital tract consists of a series of internal cavitary organs that are interconnected with the external environment through the vaginal introitus, located in the center of the urogenital triangle. This structure is responsible for the flow resulting from the physiological menstrual cycle, in addition to allowing sexual intercourse and the passage of the fetus at the time of birth (Moore, 2011). Several pathological processes have this region as a site, both through the entry of pathogenic microorganisms and through the imbalance of the microbiota residing in the geni
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Wong, Ernie, Jaideep Dhariwal, Leah Cuthbertson, et al. "An imbalanced airway microbiota correlates with greater peak flow decline in virus-induced asthma exacerbations." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.oa4415.

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Cincović, Marko, Mira Majkić, Radojica Djoković, Miloš Ži Petrović, Jovan Spasojević, and Sandra Nikolić. "DOES THE SYNERGY OF BIOTECHNOLOGICAL AND MEDICAL APPROACHES SOLVE THE CHALLENGE OF HEAT STRESS IN DAIRY COWS? AN EXAMPLE OF INSULIN RESISTANCE AND METABOLIC-HORMONAL IMBALANCE." In 3rd International Symposium on Biotechnology. University of Kragujevac, Faculty of Agronomy in Čačak, 2025. https://doi.org/10.46793/sbt30.02mc.

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Heat stress (HS) significantly impacts dairy cow productivity and welfare, primarily by inducing metabolic and hormonal imbalances, particularly insulin resistance. By examining the underlying mechanisms of HS-induced insulin resistance and its downstream consequences, we evaluate the efficacy of biotechnological strategies like genetic selection and rumen microbiome manipulation, alongside medical approaches such as nutritional supplementation and hormonal therapies in addressing this complex challenge. This review highlights the importance of a holistic approach, combining advanced biotechno
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Reports on the topic "Microbiota imbalance"

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Boulin, Tiphaine, and Hannah Moody. The microbiome and breast cancer. Breast Cancer UK, 2024. https://doi.org/10.71450/56839173.

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The human microbiome, all the microbes and their genes found in the human body, plays a key role in influencing health and the development of diseases. The role of the gut microbiome has been extensively studied in relation to breast cancer risk, showing that dysbiosis, an imbalance in bacterial composition or distribution, of the gut microbiota is linked to a higher risk of breast cancer through different mechanisms. Other microbiomes and breast cancer risk are being studied, such as the breast, breast skin and oral microbiomes; however, to date, the strongest links identified are with the gu
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