Academic literature on the topic 'Myometrium hyperplasia'

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Journal articles on the topic "Myometrium hyperplasia"

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Niauri, D. A., S. V. Chepur, Е. N. Popov, К. P. Charitonov, and I. V. Kuznetsova. "Free radical reactions in the development of combined hyperplastic processes in female reproductive system organs." Journal of obstetrics and women's diseases 54, no. 2 (2005): 31–35. http://dx.doi.org/10.17816/jowd81797.

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Intact myometrium specimen, received from 56 women of reproductive age during surgical interventions. There were 30 women with combined hyperplastic processes in the reproductive system organs (uterine myoma, endometrium hyperplasia, adenomyosis, benign ovarian tumors, mastopathy, background cervical pathology), and in 26 cases solitary uterine myoma was found. At infrared spectrometry of the lyofilized myometrium, taken from patients with combined proliferation foci, a stable peak with wave number 3500 sm1 was found, which reflects the accumulation of molecules with oxidized OHgroups and a ch
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Zhai, Junyu, Silvia Vannuccini, Felice Petraglia, and Linda C. Giudice. "Adenomyosis: Mechanisms and Pathogenesis." Seminars in Reproductive Medicine 38, no. 02/03 (2020): 129–43. http://dx.doi.org/10.1055/s-0040-1716687.

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AbstractAdenomyosis is a common disorder of the uterus, and is associated with an enlarged uterus, heavy menstrual bleeding (HMB), pelvic pain, and infertility. It is characterized by endometrial epithelial cells and stromal fibroblasts abnormally found in the myometrium where they elicit hyperplasia and hypertrophy of surrounding smooth muscle cells. While both the mechanistic processes and the pathogenesis of adenomyosis are uncertain, several theories have been put forward addressing how this disease develops. These include intrinsic or induced (1) microtrauma of the endometrial–myometrial
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Popov, Eduard N., Alexander V. Arutyunyan, Dmitry S. Sudakov, and Yulia R. Dymarskaya. "Features of proand antioxidant systems in patients with uterine leiomyoma and its combination with adenomyosis and endometrial hyperplasia and the development of recurrence after organ-saving operations." Journal of obstetrics and women's diseases 65, no. 6 (2016): 104–8. http://dx.doi.org/10.17816/jowd656104-108.

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We assessed the incidence of uterine leiomyoma recurrence after myomectomy in cases of its isolated development and combination with other hyperplastic processes of endo- and myometrium. We showed the role of pro- and antioxidant systems’ disturbances in the recurrence of combination of leiomyoma, adenomyosis and endometrial hyperplasia. We propose indole-3-carbinol and epigallocatechin administration as preventing post-operative treatment.
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Yaramareddy, Swapna, Siyonu Kumari Sardena, Nom Kumar Naik Bhukya, and Tulasi Ram Naik Menavath. "Fertility sparing treatment in an infertile patient with severe adenomyosis and a uterine fibroid: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 5 (2023): 1510–12. http://dx.doi.org/10.18203/2320-1770.ijrcog20231254.

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Adenomyosis and uterine leiomyoma are benign lesions of the myometrium. Adenomyosis is a myometrial lesion characterised by the presence of ectopic endometrium with or without hyperplasia of the surrounding myometrium. Uterine fibroids, also called leiomyomas or myomas, are benign tumours that arise from the smooth muscle of the uterus. A 33-year-old nulliparous woman attended the clinic with primary infertility for 18 years. She was diagnosed with severe adenomyosis and uterine fibroids. She conceived successfully after undergoing in vitro fertilization (IVF) and a downregulated frozen embryo
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AG, Kedrova Genrikhovna, Levakov Aleksandrovich SA, Nechaeva Evgen'evna OE, Tazitdinov Khallilovich RH, and Chelnokova Nikolaevna NN. "ULTRASOUND CRITERIA FOR DIAGNOSIS AND MONITORING OF DRUG THERAPY OF COMBINED PROLIFERATIVE DISEASES OF THE UTERUS." Journal of Clinical Practice 5, no. 3 (2014): 25–34. http://dx.doi.org/10.17816/clinpract5325-34.

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The aim of the paper was to evaluate the diagnostic accuracy of transvaginal tenderness-guided ultrasonography in the identification of location of genital endometriosis, endometrial hyperplasia and uterine fibroids before and after treatment dienogest. It is a selective progestin for the treatment of endometriosis. Adenomyosis was diagnosed when a poorly defined area of abnormal echo-texture (decreased or increased echogenicity, heterogeneous echotexture, myometrial cysts) presented in myometrium. Typical ultrasonic changes of efficacy were: homogeneity of myometrium; clear and intense contou
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Farooqui, Bushra Pervez, Uzma Shabab, Qamarunissa Muhabat Khan, Waqarunisa Khan, and Jaazba Qamar. "Role of transvaginal sonography in diagnosing adenomyosis and its correlation with histopathology." Rehman Journal of Health Sciences 7, no. 1 (2025): 18–26. https://doi.org/10.52442/rjhs.v7i1.477.

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Background: Adenomyosis represents a prevalent pathological condition within the field of gynecology, characterized by the aberrant proliferation of endometrial tissue within the myometrium of the uterus. Despite the diagnostic challenges associated with adenomyosis, this investigation underscores the significance of transvaginal sonography as a primary diagnostic modality within the context of the patient's gynecological assessment. Objectives: To find the role of transvaginal sonography in diagnosing adenomyosis and its correlation with histopathology. Methods: This cross-sectional study was
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Pujani, Mukta, Kanika Singh, Varsha Chauhan, Aparna Khandelwal, Raina Chawla, and Rashmi Ahuja. "Xanthogranulomatous Change in a Leiomyoma: First Report of an Extremely Rare Variant/Degenerative Change." Journal of Mid-life Health 14, no. 1 (2023): 60–62. http://dx.doi.org/10.4103/jmh.jmh_158_22.

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ABSTRACT Xanthogranulomatous inflammation, a specific form of chronic inflammation, is marked by parenchymal destruction, proliferative fibrosis, and infiltration of typical foamy histiocytes admixed with hemosiderin-laden macrophages and foreign-body giant cells. Myometrial xanthomatosis, a term designated for nodular or diffuse histiocytic hyperplasia of the myometrium, has been reported in association with pregnancy-related procedures. Moreover, a 2–3-fold increase in histiocytic counts has been observed in leiomyomatous areas than in adjacent normal myometrium. The first evidence of collec
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Jaffer, Shabana, Oksana Shynlova, and Stephen Lye. "Mammalian Target of Rapamycin Is Activated in Association with Myometrial Proliferation during Pregnancy." Endocrinology 150, no. 10 (2009): 4672–80. http://dx.doi.org/10.1210/en.2009-0419.

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Abstract The adaptive growth of the uterus during gestation involves gradual changes in cellular phenotypes from the early proliferative to the intermediate synthetic phase of cellular hypertrophy, ending in the final contractile/labour phenotype. The mammalian target of rapamycin (mTOR) signaling pathway regulates cell growth and proliferation in many tissues. We hypothesized that mTOR was a mediator of hormone-initiated myometrial hyperplasia during gestation. The protein expression and phosphorylation levels of mTOR, its upstream regulators [insulin receptor substrate-1, phosphoinositide-3-
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Butler, Trent, Jonathan Paul, Nick Europe-Finner, Roger Smith, and Eng-Cheng Chan. "Role of serine-threonine phosphoprotein phosphatases in smooth muscle contractility." American Journal of Physiology-Cell Physiology 304, no. 6 (2013): C485—C504. http://dx.doi.org/10.1152/ajpcell.00161.2012.

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The degree of phosphorylation of myosin light chain 20 (MLC20) is a major determinant of force generation in smooth muscle. Myosin phosphatases (MPs) contain protein phosphatase (PP) 1 as catalytic subunits and are the major enzymes that dephosphorylate MLC20. MP regulatory targeting subunit 1 (MYPT1), the main regulatory subunit of MP in all smooth muscles, is a key convergence point of contractile and relaxatory pathways. Combinations of regulatory mechanisms, including isoform splicing, multiple phosphorylation sites, and scaffolding proteins, modulate MYPT1 activity with tissue and agonist
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Serteva, D., E. Poryazova, and Ts Velikova. "Endometriosis Locations and Coexistence with other Uterine Conditions in a Bulgarian Sample of Patients." American International Journal of Multidisciplinary Scientific Research 5, no. 2 (2019): 5–9. http://dx.doi.org/10.46281/aijmsr.v5i2.255.

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Endometriosis is a non-tumor, estrogen-dependent, chronic gynecological disease, which is characterized by the presence of endometrial glands and stroma outside the endometrium of the uterus. Endometriosis affects between 10% and 15% of women in reproductive age. It is often associated with chronic pelvic pain and reproductive difficulties. Endometriosis can be classified as ovarian, extra-ovarian or mixed. Adenomyosis is considered, by some authors, as a separate variant of endometriosis. It is diagnosed as the presence of ectopic benign endometrial glands and stroma in the myometrium, where
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Dissertations / Theses on the topic "Myometrium hyperplasia"

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Нікітіна, Ірина Миколаївна, Ирина Николаевна Никитина, Iryna Mykolaivna Nikitina та ін. "Ефективні методи діагностики та лікування хворих з гіперпластичними процесами ендо- та міометрія". Thesis, Сумський державний університет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41803.

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Досліджено методи покращення результатів лікування та якості життя жінок репродуктивного та пременопаузального віку з гіперпластичними процесами ендо- і міометрія шляхом органозберігаючих лікувальних технологій.
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Book chapters on the topic "Myometrium hyperplasia"

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Tsikouras, Panagiotis, Fotini Gaitatzi, Stefani Filiou, et al. "Uterine Embolization as a New Treatment Option in Adenomyosis Uteri." In Endometriosis - Recent Advances, New Perspectives and Treatments [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.101480.

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Adenomyosis is characterized by the development of endometrial ectopic glands and tissue in the myometrium layer in depth greater than 2.5 mm from the endometrial surface of the separative area by -myomas well as by hypertrophy and hyperplasia of the smooth muscles of the myometrium. This is filtration, not mere displacement, of the myometrium, from the endometrium. Clinical symptoms include dysmenorrhea and menorrhagia. It is diffuse (adenomyosis) or focal (adenomyoma), asymmetrically affects the uterine wall of premenopausal women (usually the posterior) and often coexists with myomas. The p
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Gadducci, Angiolo, and Roberta Tana. "Endometrial Cancer and Fertility." In NEOPLASIA and FERTILITY. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815050141122010004.

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Endometrial carcinoma is the most common gynecological malignancy in the western countries. Although majority of patients are postmenopausal, 2.5–14.4% of the cases are detected in women aged <40 years. The tumors diagnosed in young women are usually early-stage, low-grade endometrioid endometrial carcinoma [EEC]s with favorable clinical outcomes. The standard primary therapy consists of extra-fascial hysterectomy and bilateral salpingo-oophorectomy with or without node dissection. However, a fertility-sparing treatment is feasible in accurately selected young women with complex atypical hy
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Koga, Adriana Yuriko, Edmar Miyoshi, João Pedro Gambetta Polay, Bianca Cristina Cardoso, Paulo Vitor Farago, and Leandro Cavalcante Lipinski. "EVALUATION OF HISTOLOGICAL CHANGES IN THE UTERUS OF RATS TREATED WITH ALGINATE FILM CONTAINING 17-Β ESTRADIOL NANOPARTICLES." In Foundations and Frontiers: The Dynamics of Multidisciplinary Sciences. Seven Editora, 2025. https://doi.org/10.56238/sevened2025.021-026.

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OBJECTIVE: This study aims to investigate the effect of film containing 17-β estradiol nanoparticles on uterine tissue. The primary focus is on assessing their potential as precise hormonal therapy for skin lesions in oophorectomized rats. METHODS: The research involved the development of an alginate film containing 17-β estradiol nanoparticles. The animal assay was conducted on oophorectomized rats with dorsal skin lesions measuring 4 cm². The rats were divided into three groups: one treated with the alginate film, the second with a film containing conventional 17-β estradiol, and the third w
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Conference papers on the topic "Myometrium hyperplasia"

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Suhargo, Listijani, and Dwi Winarni. "The Utilization of Graptophyllum pictum (L) Griff. Extract as the Endometrial and Myometrial Hyperplasia Inhibitor of Ovariectomized Mice." In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008358101020105.

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Singhal, Seema, Sunesh Kumar Jain, D. N. Sharma, et al. "Clinicopathological analysis of early endometrial cancers." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685344.

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Aim: The study objectives were evaluation of clinicopathological characteristics, correlations between the preoperative and postoperative tumor assessment in early stage endometrial cancer. Materials and Methods: We conducted a prospective descriptive study of 30 cases of endometrial cancer stage 1 examined and treated at a tertiary care teaching institute between the years 2014-15. Results: The patients’ mean age at the time of diagnosis was 56.4 years. The mean parity was two. Postmenopausal bleeding with or without abnormal vaginal discharge was the most frequent symptom; it was present in
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Singhal, Seema, Sunesh Kumar Jain, D. N. Sharma, et al. "Clinicopathological analysis of early endometrial cancers." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685338.

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Aim: The study objectives were evaluation of clinicopathological characteristics, correlations between the preoperative and postoperative tumor assessment in early stage endometrial cancer. Materials and Methods: We conducted a prospective descriptive study of 30 cases of endometrial cancer stage 1 examined and treated at a tertiary care teaching institute between the years 2014-15. Results: The patients’ mean age at the time of diagnosis was 56.4 years. The mean parity was two. Postmenopausal bleeding with or without abnormal vaginal discharge was the most frequent symptom; it was present in
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