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Relevant bibliographies by topics / Nano-formulation / Dissertations / Theses

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Dissertations / Theses on the topic 'Nano-formulation'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Arulmuthu, Eugene Raj. "Formulation and aerosol delivery of nano-sized biomaterials." Thesis, Loughborough University, 2007. https://dspace.lboro.ac.uk/2134/33593.

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The aim of this research has been to study and develop the engineering principles associated with the impact of formulation and device parameters on the safe delivery of nano-sized biomaterials such as plasmid DNA. In the present investigation, Omron U22 and U03 mesh nebulisers operating at frequencies of ~175 kHz and ~65 kHz respectively were used. Since the U22 device is a recently introduced mesh nebuliser for respiratory drug delivery, detailed characterisation, experimentation, modelling and analysis was carried out for this device. Plasmids of size 5.7, 8.7, 13 and 20 kb were purified fr

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2

Lasfargues, Mathieu. "Nitrate based high temperature nano-heat-transfer-fluids : formulation & characterisation." Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/7531/.

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This work relates to the development of high temperature heat-transfer-fluid with enhanced specific heat capacity using nano-particle additives. A eutectic mixture of nitrate (60 wt% NaNO3 & 40 wt% KNO3) was produced through ball-milling and characterised on DSC, TGA, Rheometer. The results obtained showed that the salt mixture melted at 221°C with a heat of fusion of 97 J/g. Onset of melting was seen at 215°C whilst crystallisation started at 219°C, reaching a solid state below 217°C with an enthalpy of 97 J/g. Displaying very little overcooling, the salt showed specific heat capacity of 1.41

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3

Chatzidaki, Maria D. "Formulation and characterization of W/O nano-dispersions for bioactive delivery applications." Doctoral thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-49454.

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The main objective of this study was the formulation of food-grade water-in-oil (W/O) nano-dispersions based mainly on medium or long-chain triglycerides. Two types of dispersions were formulated and structurally compared, namely emulsions and microemulsions. The systems were used as matrices for encapsulating targeted bioactive molecules with specific characteristics such as antioxidants or peptides. The structural characterization of the formulated systems was investigated using techniques such as Electron Paramagnetic Resonance (EPR) spectroscopy, Dynamic Light Scattering (DLS), Cryogenic T

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4

Elahi, Shabnam. "Formulation of nano-structured emulsions for use in food and healthcare applications." Thesis, University of Bath, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683536.

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Nano-emulsions are a centre of attention for many industrial applications in different fields such as pharmaceutical, cosmetic, food and agriculture due to their interesting physical properties such as transparency, larger surface area to volume ratio and long-term physical stability. This PhD project focuses on the preparation of stable nano-emulsions using different emulsification methods with an attempt to find the optimum formulation to produce stable nano-emulsions for food and healthcare applications. The emulsification methods studied in this project were rotor-stator homogeniser (Ultra

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5

Ahmad, Nadeem. "LHRH-Receptor Mediated Targeting of Cancer Cells Using Curcumin Nano-micelle Formulation." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20894.

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Breast cancer is the most common malignancy and the second leading cause of cancer-related death among Australian women despite existing progress in the development of novel therapeutic strategies. Triple-negative breast cancer (TNBC), accounting for 10-17% of all breast carcinomas, represents an important clinical challenge in therapeutic demand. In this project, we fabricated, characterized and biologically evaluated nanoparticles (NPs) loaded with curcumin. We prepared curcumin-loaded nano-micelles with and without peptide conjugation. The [k6]LHRH-curcumin-NPs ([k6]LHRH-Cur-NPs), [k6(Ahx)

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6

Hallouard, François. "Formulation de nano-particules iodées comme agents de contraste a longue rémanence vasculaire pour tomodensitométrie." Thesis, Lyon 1, 2012. http://www.theses.fr/2012LYO10307.

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L’objectif de cette thèse est de réaliser un agent de contraste vasculaire pour tomodensitométrie utilisable en préclinique. En collaboration avec le laboratoire de biogalénique de Strasbourg, ce travail a permis d’obtenir des nano-émulsions iodées produites par diffusion spontanée de surfactif et des nanoparticules iodées produites par ”émulsion - diffusion de solvant”, comme agent de contraste vasculaire. Ces émulsions et particules polymériques présentent en effet, un temps de rémanence vasculaire de plusieurs heures, un pouvoir contrastant suffisant pour un usage en tomodensitométrie (comp

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7

Marino, Helene. "Phase inversion temperature emulsification : from batch to continuous process." Thesis, University of Bath, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533407.

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8

Fahs, Ahmad. "Structure and Physicochemical Properties of Hydroxypropyl Methylcellulose (HPMC) Formulated Films for Pharmaceutical Applications : Relevance to Surface Properties." Thesis, Mulhouse, 2009. http://www.theses.fr/2009MULH2968.

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L’Hydroxypropyle méthylcellulose (HPMC) constitue un des polymères les plus utilisés pour la production de films destinés aux applications pharmaceutiques (gélules, comprimés, etc.). Afin de contrôler les propriétés physico-chimiques de films HPMC, des additifs sont fréquemment incorporés pendant la formulation du film: ce sont dans la plupart des cas un lubrifiant hydrophobe (acides gras) ou un plastifiant hydrophile (le polyéthylène glycol). L’objectif principal de ce travail est d’étudier les propriétés physico-chimiques en volume et en surface des films HPMC formulés aux échelles nanoscopi

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9

Nakach, Mostafa. "Stabilization and comparison of manufacturing technologies for production of nano-crystalline suspensions." Thesis, Ecole nationale des Mines d'Albi-Carmaux, 2016. http://www.theses.fr/2016EMAC0007/document.

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La faible taille des nanoparticules permet d’améliorer significativement la biodisponibilité des médicaments et faciliter leur administration par voie parentérale sous forme de particules sans risque de bouchage des vaisseaux sanguins. Cependant, cette faible taille peut être un facteur d’instabilité physique pendant le stockage ou/et pendant l’administration. Le principal défi lié à la fabrication des nano-suspensions réside dans leur stabilisation ainsi que dans le choix de la technologie appropriée pour leur fabrication. La présente thèse est centrée sur la stabilisation et la fabrication d

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10

Ennahali, Mohamed. "Stabilisation des nano-particules dans les suspensions liquides de polissage mécano-chimique." Aix-Marseille 3, 2007. http://www.theses.fr/2007AIX30062.

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L'industrie des semi-conducteurs doit trouver des méthodes et des procédés de plus en plus efficaces. Parmi les nouvelles méthodes qui sont de plus en plus utilisées, le polissage mécano-chimique (CMP) est celle qui a plus évolué durant les trente dernières années et reste le procédé le plus efficace et fiable pour miniaturiser les puces. Le CMP utilise des liquides de polissage appelés aussi « Slurries » à base de nano particules abrasive pour polir des surfaces très différentes. La stabilité des liquides de polissage est un problème important. Les propriétés physico-chimiques du milieu et le

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11

Guezennec, Céline. "Développement de nouveaux matériaux d'emballage à partir de micro- et nano-fibrilles de cellulose." Thesis, Grenoble, 2012. http://www.theses.fr/2012GRENI067/document.

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Développement de nouveaux matériaux d'emballage à base de micro- et nano-fibrilles de cellulose. Les micro- et nano-fibrilles de cellulose (MFC/NFC) sont des nanomatériaux issus de ressources renouvelables présentant un fort intérêt notamment pour le domaine de l'emballage. En plus des avantages naturels de la cellulose, ces matériaux offrent des propriétés barrières prometteuses (Oxygen, graisse), de bonnes propriétés de résistance mécanique ainsi que la possibilité de produire des films transparents. L'objectif de cette thèse était de développer par des procédés d'endution un carton barrière

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12

Tsai, Yin-Meng, and 蔡吟孟. "Pharmacokinetics of curcumin and its nano-formulation in rats." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/20753932624061035569.

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博士<br>國立陽明大學<br>傳統醫學研究所<br>99<br>Curcumin is a yellow polyphenol extracted from the root of Curcuma longa Linn with several types of bioactivity, but with low bioavailability. Hence, this study has optimized the poly (lactic-co-glycolic acid) (PLGA) nano-formulation of curcumin to improve its bioavailability and evaluate its organ distribution after formulation. High-pressure emulsification–solvent-evaporation method was designed to obtain curcumin-loaded PLGA nanoparticles (C-NPs) prepared with 2% of poly(vinyl alcohol) containing 20% sucrose as aqueous phase and dichloromethane as oil phase.

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13

Jiang, Ke-Di, and 江科迪. "Preparation, characterization and pharmacokinetic evaluation of curcumin loaded solid dispersion and nano-formulation." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/hbrd4b.

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碩士<br>高雄醫學大學<br>藥學系碩士班<br>103<br>The purpose of this study is to develop curcumin loaded solid dispersion and nano-formulation which could enhanced the aqueous solubility and oral bioavailability of curcumin. We used two materials to prepare solid dispersion formulation in our study. Three formulations in different ratio was curcumin: polyvinylpyrrolidone K30:vitamin E TPGS=10:70:20, 10:75:15, 10:80:10 (w/w/w). The characterization of solid dispersion included solubility, dissolution, measurement of drug content, differential scanning calorimetry, fourier transform infrared spectroscopy. The c

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14

Yeh, Wei-Ting, and 葉威廷. "The Study on Formulation of Photo-sensitive Resin with Carbon Black Nano-particles." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/74452309612576097935.

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碩士<br>國立中興大學<br>化學工程學系<br>93<br>The next generation TFT-LCD is gradually developing for light, full-color and mobile display. Therefore, the color filter that plays a key element of TFT-LCD is to be improved for ultra high resolution and precision pattern by using nano-technology. That is it needs to decrease the distance between pixels and to increase aperture ratio. As a result, it’s importance research to develop new material with higher optical density, lower conductivity, and free environmental problem for finer black matrix. With the property of larger specific surface area, lower cont

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15

Wan-RuChang and 張婉如. "Synthesis of a novel blood-brain-barrier-penetrating nano-formulation for brain tumor therapeutics." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/558n69.

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碩士<br>國立成功大學<br>口腔醫學研究所<br>103<br>Brain tumor is one of worst prognosis malignancy of human that effective clinical therapeutic strategies remained to be explored. Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. GBM displays aggressive growth and invasion to the surrounding brain tissues, leading to a median survival time only about 1 year. Current traditional therapeutics only showed limited efficacy, especially for chemotherapeutic drugs that blood-brain barrier (BBB) presented to be a major challenge for traditional medication to reach cancerous area in the b

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16

Chao, Yun, and 趙澐. "Evaluation the effect of flavonoids and its nano-formulation on improving the symptom of interstitial cystitis." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/51459226453802945941.

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碩士<br>高雄醫學大學<br>藥學研究所<br>98<br>Interstitial cystitis (IC) is a inflammation condition of bladder. Its clinical syndrome characterized by bladder pain, irritative voiding symptoms, and sterile urine. Although the pathogenesis of IC is uncertain, it has been proposed that a dysfunctional epithelium allows the transepithelial migration of solute, such as potassium, that can depolarize sub-epithelial afferent nerves and provoke sensory symptoms. Flavonoids are common secondary metabolites in plant kingdom. Studies have showed that flavonoids inhibit oxidation or nitric oxide producing. iNOS induc

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17

Chi, Chen Hsien, and 紀政嫻. "The development and evaluation on drug delivery systems for anti-Parkinson drugs: nano-carriers for injection and transdermal delivery formulation." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/73171108164281215802.

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碩士<br>長庚大學<br>天然藥物研究所<br>97<br>Apomorphine is a non-selective agonist of D1 and D2 dopamine receptors. Apomorphine is a very effective drug in the management of ‘on-off’ motor response fluctuations in the treatment of Parkinson’s disease. The aim of this present work was to develop acoustically active lipid-coated microbubbles for encapsulation of both apomorphine hydrochloride and apomorphine base to circumvent these delivery problems. The lipid-coated microbubbles were prepared using coconut oil and perfluoropentane as the inner phase, which was emulsified by phospholipids and cholesterol. T

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18

Huynh, Loan. "Rational Design of Drug Formulations using Computational Approaches." Thesis, 2012. http://hdl.handle.net/1807/35730.

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Theory has been used to complement experiment in the development of both drugs and delivery systems. Theoretical methods are capable of identifying the molecular basis of drug formulation inadequacies and systematic theoretical studies may suggest fruitful avenues for material modification. This thesis highlights the utility of computer-based theoretical calculations for guiding the design of drug formulations and enhancing material-drug compatibility and stability. Specifically, the present work explores the applications of semi-empirical methods and atomistic molecular dynamics (MD) simulati

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