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Journal articles on the topic 'Nano-formulation'

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1

Vikas B,, Vikas B,, Sanjai Gunawanth R, Ahalya R. Ahalya R, Kiruthiga K. M. Kiruthiga K M, and Lavanya S. Lavanya S. "Nano Formulation of Breast Cancer." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 984–90. https://doi.org/10.35629/4494-0906984990.

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Breast cancer remains one of the leading causes of cancer-related deaths worldwide, necessitating the development of innovative therapeutic strategies.Breast cancer is a disease that occurs when breast cells grow out of control and form tumors.Bioactive compounds are chemical substances found in plants and some foods that can positively affect human health. This study explores the potential of a novel nanoformulation using bioactive compounds derived from clove (Syzygium aromaticum), poppy seeds (Papaver somniferum), and licorice (Glycyrrhiza glabra) for breast cancer treatment. These natural
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Mohanty, Harshita, and Raman P. Yadav. "Curcumin nano-formulation with enhanced pancreatic lipase inhibition." MGM Journal of Medical Sciences 12, no. 2 (2025): 340–44. https://doi.org/10.4103/mgmj.mgmj_77_25.

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Abstract Background: Curcumin has been recognized for its diverse therapeutic effects. Little is known about the impact of curcumin on pancreatic lipase inhibition. In recent years, researchers have explored curcumin with new and improved properties. This study evaluated a nano-formulation of curcumin using Tween 80 for its inhibitory effect on porcine pancreatic lipase. The nano-formulation demonstrated significant enzyme inhibition in vitro. Materials and Methods: A pancreatic lipase assay was conducted using p-nitrophenol palmitate as a synthetic substrate. To determine the inhibitory activ
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Gupta, Ajay. "Silveron Gel (Nano Silver Formulation): A Powerful Antimicrobial for the Future." New Indian Journal of surgery 12, no. 4 (2021): 209–13. http://dx.doi.org/10.21088/nijs.0976.4747.12421.2.

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Introduction: Nano silver itself is not new. It has been used for various applications in consumer and commercial products over the past century without showing adverse effects on patients. Nano-silver dispersions were used as medical products already in the 19th century. Additionally, the concept of Nano-silver being used as a topical antibacterial dates back to the days of Sushrut in the 6th century where finely powdered Silver was used as a topical antibacterial/antiseptic after surgery. Material and Method: Silver ions and the compounds made like nanosilver exhibit a broad antimicrobial pr
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Tanuku, Srivalli, Dedeepya Velisila, Dharani Thatraju, and Anil kumar Vadaga. "Nanoemulsion Formulation Strategies for Enhanced Drug Delivery." Journal of Pharma Insights and Research 2, no. 4 (2024): 125–38. http://dx.doi.org/10.69613/3f8m9151.

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Nano emulsions are emerging as versatile drug delivery systems, offering enhanced solubility, dissolution, absorption, permeation, and bioavailability due to their nano-sized droplets and extensive interfacial area. Both high-energy and low-energy techniques are employed for nano emulsion preparation, including high-pressure homogenization, ultrasonication, phase inversion composition (PIC), and phase inversion temperature (PIT) methods. Nano emulsions demonstrate advantages in improving the stability and bioavailability of therapeutic agents, addressing common challenges such as creaming, flo
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Kusumo, Galuh Gondo, and Damaranie Dipahayu. "The Effect of Nano Extract Formulation on Antioxidant Activity of 70% Ethanolic Extract of Purple Sweet Potato’s Leaves (Ipomoea batatas L.) Antin-3 Variety." Journal Pharmasci (Journal of Pharmacy and Science) 7, no. 1 (2022): 43–47. http://dx.doi.org/10.53342/pharmasci.v7i1.270.

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Purple sweet potato leaves contain anthocyanins with high antioxidant activity but are rarely used. To increase the activity of a natural product, nanoparticle formulation in the extract can be used. It can increase the absorption of the product in the gastrointestinal tract. However, the formulation of natural ingredients used for antioxidants can affect their activity. This study aimed to determine the effect of the nano extract formulation on the antioxidant activity of the leaf extract of purple sweet potato (Ipomoea batatas L.) antin-3 variety. The ionic gelation method carried out the ma
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RAJ, BRITO. "Investigating the influence of lipids on Nano-structured lipid carrier formulation." Journal of Medical pharmaceutical and allied sciences 12, no. 6 (2023): 6147–54. http://dx.doi.org/10.55522/jmpas.v12i6.5220.

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The study aimed to evaluate the effect of different lipids on the properties of nanostructured lipid carrier (NLC) formulations. The particle size, zeta potential, polydispersity index, entrapment efficiency, and drug release at 24 hours were analyzed for formulations containing various lipid matrices. Among the formulations tested, N3 (Compritol 888 ATO and Softigen) exhibited the most favourable characteristics, including the smallest particle size, highest entrapment efficiency, sustained drug release, and good stability, as indicated by a high zeta potential. Other lipids, such as Witepsol
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MEDELEANU, Mădălina Lorena, Anca Corina FĂRCAȘ, Cristina COMAN, et al. "Citrus essential oils nano-emulsions: formulation and characterization." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Food Science and Technology 81, no. 2 (2024): 1–22. http://dx.doi.org/10.15835/buasvmcn-fst:2024.0011.

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The use of citrus essential oils nano-emulsions (CEO-NE) plays a crucial role in enhancing food safety. This is achieved through various mechanisms such as the enhancement of organoleptic properties, increased bioavailability of bioactive components from essential oils, controlled release of key compounds for long-term efficacy, and extension of the shelf life of food and beverages (antioxidant and antimicrobial activity). In this work, CEO-NEs, formulated with different types of citrus essential oils, Tween 80, and alcohol, were obtained by magnetic stirring combined with ultrasound method. T
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Astuti, A., and V. V. Matara. "Effect of nano-formulated indigenous Rhizobium sp. on nodulation, growth, and yield of Edamame soybean." IOP Conference Series: Earth and Environmental Science 985, no. 1 (2022): 012023. http://dx.doi.org/10.1088/1755-1315/985/1/012023.

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Abstract The isolates of indigenous Rhizobium sp. are compatible with Edamame soybean, but the inoculum formulation using a carrier material from ordinary peat has not been optimal. The study was aimed to evaluate the effects of the nano-formulation of indigenous Rhizobium sp. inoculum on the growth and yield of Edamame soybean. The research was arranged in a randomized complete block design using a single factor treatment, namely the inoculum formulae, consisting of Nano Peat 95% + Nano Biochar 5%, Nano Peat 95% + Nano Bone 5%, Nano Peat 90% + Nano Biochar 5% + Nano Bone 5%, and Peat 50% + Ch
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Nigam, Kuldeep, Reema Gabrani, and Shweta Dang. "Nano-emulsion from Capsaicin: Formulation and Characterization." Materials Today: Proceedings 18 (2019): 869–78. http://dx.doi.org/10.1016/j.matpr.2019.06.517.

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Sharma, Shivani, Neha Loach, Shweta Gupta, and Lalit Mohan. "Phyto-nanoemulsion: An emerging nano-insecticidal formulation." Environmental Nanotechnology, Monitoring & Management 14 (December 2020): 100331. http://dx.doi.org/10.1016/j.enmm.2020.100331.

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Mazloumi Tabrizi, Maral, Sepideh Jafarzadeh Rastin, Nahid Kabiri, and Azim Akbarzadeh Khiyavi. "Synthesis of Paclitaxel Loaded on Nanoparticles of Archaeosomes and Investigation of Its Anti-cancer Properties." Asian Pacific Journal of Cancer Biology 2, no. 3 (2017): 67–70. http://dx.doi.org/10.31557/apjcb.2017.2.3.67-70.

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Objective: In this study, the effect of archaeosomal paclitaxel drug on breast cancer MDA-MB231 cell lines was evaluated. Material and method: The experiments were conducted to assess the cytotoxicity of paclitaxel in free form and compare it with archaeosomal form of the drug in vitro. To check the size of archaeosomes, Zetasizer device (DLS) was used. The average size of archaeosom nanoparticles containing paclitaxel drugs 430 nm and surface charge -15 and the average size of control archaeosom nanoparticles without drug 460 nm and surface charge -14 were reported. The effect of archaeosomal
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Akram, Salman, Nicolas Anton, Ziad Omran, and Thierry Vandamme. "Water-in-Oil Nano-Emulsions Prepared by Spontaneous Emulsification: New Insights on the Formulation Process." Pharmaceutics 13, no. 7 (2021): 1030. http://dx.doi.org/10.3390/pharmaceutics13071030.

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Nano-emulsions consist of stable suspensions of nano-scaled droplets that have huge loading capacities and are formulated with safe compounds. For these reasons, a large number of studies have described the potential uses of nano-emulsions, focusing on various aspects such as formulation processes, loading capabilities, and surface modifications. These studies typically concern direct nano-emulsions (i.e., oil-in-water), whereas studies on reverse nano-emulsions (i.e., water-in-oil) remain anecdotal. However, reverse nano-emulsion technology is very promising (e.g., as an alternative to liposo
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Yang, X., T. C. Ong, V. K. Michaelis, et al. "Formation of organic molecular nanocrystals under rigid confinement with analysis by solid state NMR." CrystEngComm 16, no. 39 (2014): 9345–52. http://dx.doi.org/10.1039/c4ce01087f.

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Wang, Kuilong. "Mini Review: Nano-Technology based Drug Deliveries." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 268–71. http://dx.doi.org/10.22270/jddt.v8i6.2053.

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Targeted drug delivery with nano-technology has been researched and identified as being efficient across many treatment conditions. This review assesses some of the existing research work and evidence practice in using nano-technology based drug carriers.
 Keywords: Nano-technology, drug delivery, nanoparticle formulation, nano-technology carriers, drug resistance
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Deaguero, Isaac G., Md Nurul Huda, Victor Rodriguez, et al. "Nano-Vesicle Based Anti-Fungal Formulation Shows Higher Stability, Skin Diffusion, Biosafety and Anti-Fungal Efficacy In Vitro." Pharmaceutics 12, no. 6 (2020): 516. http://dx.doi.org/10.3390/pharmaceutics12060516.

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Opportunistic fungal infections are responsible for over 1.5 million deaths per year. This has created a need for highly effective antifungal medication to be as potent as possible. In this study, we improved the efficacy of a common over the counter (OTC) antifungal skin medication, miconazole, by encapsulating nano-molecules of the drug in cholesterol/sodium oleate nano-vesicles. These nano-vesicles were characterized to optimize their size, zeta potential, polydispersity index and encapsulation efficiency. Furthermore, these nano-vesicles were compared to a conventional miconazole-based com
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Ghafari, Fatemeh, Zohre Sadeghian, Akram Oftadeh Harsin, Sodabe Khodabandelo, and Akram Ranjbar. "Anti-oxidative properties of nanocrocin in Zearalenone induced toxicity on Hek293 cell; The novel formulation and cellular assessment." Human & Experimental Toxicology 42 (April 18, 2023): 096032712311699. http://dx.doi.org/10.1177/09603271231169911.

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Background Zearalenone (ZEA) is a mycotoxin produced by fungi and induces cytotoxicity by the generation of reactive oxygen species. The aim of this study was to evaluate and compare the nephroprotective effects of crocin and nano-crocin against ZEA-induced toxicity in HEK293 cell line via modulation of oxidative stress and special formulation to make nano-crocin. Method Nano-crocin physicochemical properties, such as size, load, appearance, and drug release profile were determined. Also, the viability of intoxicated HEK293 cells was evaluated by MTT assay. Furthermore, lactate dehydrogenase l
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Oliveira, Gustavo Vieira de, Mônica Volino-Souza, Karen Souza dos Santos, Yunes Scarpine Malheiros, Carlos Adam Conte-Júnior, and Thiago Silveira Alvares. "A perspective on the use of polyphenols nano-formulation as a nutritional strategy to manage the symptoms of the infected patient with COVID-19." Research, Society and Development 10, no. 13 (2021): e400101321471. http://dx.doi.org/10.33448/rsd-v10i13.21471.

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Coronaviruses disease (COVID-19) vaccines have emerged worldwide to control this illness, albeit they cannot guarantee full effectiveness. Polyphenols possess antioxidant, anti-inflammatory, and antiviral properties, all of which may be effective against COVID-19 symptoms. Since polyphenols exhibit low bioavailability, polyphenols nano-formulation (a food technology) have been utilized in COVID-19 patients. Therefore, the purpose of this review is to discuss the current evidence showing the effects of polyphenols nano-formulation in COVID-19 patients. Two previous studies have demonstrated tha
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Kaneko, Kenichi, Ryosuke Miyasaka, and Roslyn Hayman. "Nano-hydroxyapatite improves intestinal absorption of acetazolamide (BCS Class IV drug)–but how?" PLOS ONE 17, no. 5 (2022): e0268067. http://dx.doi.org/10.1371/journal.pone.0268067.

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We earlier reported that coating poorly water-soluble drugs with nano-hydroxyapatite (nano-HAP) improves bioavailability after oral administration. In the present study, we coated BCS Class IV drug acetazolamide (AZ) with nano-HAP (AZ/HAP formulation), and investigated its bioavailability and nano-HAP’s role in promoting it. We tested AZ bioavailability after a single oral dose of the AZ/HAP formulation in rats, followed by a series of in vitro, ex vivo and in vivo testing. The binding state of AZ and nano-HAP was analyzed by gel filtration chromatography. AZ permeability was studied using a C
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B, Senthilnathan, Billy Graham R, Chaarmila Sherin C, Vivekanandan K, and Bhavya E. "Anticancer Nano Formulation of Imatinib with Chitosan Polymer." International Journal of Drug Delivery Technology 9, no. 01 (2019): 58–64. http://dx.doi.org/10.25258/ijddt.9.1.10.

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Objective: Drug targeting is the capacity of the dosage form. In which the therapeutic agent acts specifically to desired site of action in the non-targeted tissue with the help of Nano particles is called as the drug targeting. IMATINIB is a used to treat cancer by chemo therapy. Cancers like chronic myeloid leukemia cancer (CML) and acute lymphoblastic leukemia cancer (ALL) and other specific types of gastrointestinal stromal cell tumor (GIST) systemic mast cell disease and Bone marrow failure disorder. It is administered by oral root. For ATP, Tyrosine kinase is act as a binding site. Metho
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Kamran, Mahwish, Mir Azam Khan, Muhammad Shafique, et al. "Development and Characterization of Binary Solid Lipid Nano Suspension of Atorvastatin: In-Vitro Drug Release and In-Vivo Pharmacokinetic Studies." Nanoscience and Nanotechnology Letters 11, no. 11 (2019): 1522–30. http://dx.doi.org/10.1166/nnl.2019.3039.

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Atorvastatin is an extensively used lipid lowering agent. But the vital issue associated with it is low oral bioavailability (12%) owing to poor aqueous solubility. To overcome this tribulation, binary solid lipid nano suspension of Atorvastatin (ATO) was formulated by solvent diffusion method. The combination of stearic acid and oleic acid was utilized as a lipid carrier with Tween-80 (surfactant) along with Polyvinylpyrrolidone (co-surfactant). Optimized nano formulation was prepared by changing the formulation variables. Optimized nano suspension (ATO-4) represented particle size 228.3 ± 2.
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Ravi, Kaveena26, and Kirubha Hari.C K. "Designing Pediatric Nano-formulations Faces a slew of Obstacles: A Review." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 33, no. 1 (2024): 11–22. http://dx.doi.org/10.31351/vol33iss1pp11-22.

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Nanotechnology is a fine tool for enhancing drug efficiency. Doses and medication development for Pediatric Population still remains a challenge.The clinical experience gained from treating adults is usually used in pediatric therapies.Although science has proven that children's pharmacokinetics and pharmacodynamics differ from adult.When applied to children, innovative technologies (e.g., nanotechnology) are highly challenging to implement. An optimal formulation has to be in an acceptable dose type where the pediatric patients can accommodate. Due to its complicated existence, comparatively
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Tambade, Mayuresh, Shweta Shriwas, and Dr Rakesh Kumar Jatav. "“Formulation and Evaluation of Nano-Gel Using Effective Combination of Acyclovir and Omeprazole for Enhanced AntiViral Activity”." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 80–97. https://doi.org/10.35629/4494-09068097.

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The aim of the research is to formulate nano transdermal using effective combination ofacyclovir and omeprazole to enhanced anti-viral activity to evaluate the Preformulating characters to formulate acyclovir and omeprazole nanogel by solvent diffusion method to Characterization and evaluation of formulated nanogel compare the in-vitro drug release with marketed formulation. It can be concluded that the experimental study carried out that the formulation of a Nanogel containing anti-viral drug and anti-ulcer drug yields a formulation with spherical and smooth surface, nano in size range. The p
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Kalamani, Velmurugan, Vijayakumar S., Shreya Ramesh, et al. "In-vitro antioxidant, the antimicrobial and anticarcinogenic activity of environment friendly nano formulation using Mangifera indica." Maejo International Journal of Energy and Environmental Communication 4, no. 2 (2022): 43–49. http://dx.doi.org/10.54279/mijeec.v4i2.248123.

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The green synthesis of nanoparticles (NPs) from plant extracts is an innovative and considered as an effective method, which has many biological and therapeutic benefits. In this regard, silver nanoparticles were synthesized from leaves of Mangifera indica (Mango) and their properties were characterized. Morphological characterizations such as UV-Visible Spectroscopy (UV-Vis), Fourier-Transform Infra-red Spectroscopy (FTIR), and X-ray diffraction (XRD) confirm the physical characteristics of silver nano-particles. In addition, Mangifera indica phytochemicals possesses DPPH radical scavenging a
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Kapoor, Hema, Mohd Aqil, Syed Sarim Imam, Yasmin Sultana, and Asgar Ali. "Formulation of amlodipine nano lipid carrier: Formulation design, physicochemical and transdermal absorption investigation." Journal of Drug Delivery Science and Technology 49 (February 2019): 209–18. http://dx.doi.org/10.1016/j.jddst.2018.11.004.

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Bahadori, Fatemeh, Gülaçtı Topçu, Mehmet S. Eroğlu, and Hayat Önyüksel. "A New Lipid-Based Nano Formulation of Vinorelbine." AAPS PharmSciTech 15, no. 5 (2014): 1138–48. http://dx.doi.org/10.1208/s12249-014-0146-3.

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Sharma, Shaveta, Jashanpreet Kaur, and Jyoti Singh. "Formulation and Characterization of Moringa Oleifera Nano Particles." CGC International Journal of Contemporary Technology and Research 6, no. 2 (2024): 411–14. http://dx.doi.org/10.46860/cgcijctr.2024.06.10.411.

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The synthesis of copper oxide nano particles (CuO NPs) using moringa oleifera leaves extract as a green reducing agent has gained significant interest due to its eco-friendly and cost-effective nature. Moringa oleifera leaves extract acts as a reducing agent and capping agent simultaneously, making it a promising alternative to traditional methods. The size, shape, and optical properties of the synthesized CuO NPs can be controlled by varying the concentration of moringa oleifera leaves extract and reaction time. The synthesized CuO NPs exhibit excellent antimicrobial, antioxidant, antiviral,
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Chen, James, and James D. Lee. "Atomic Formulation of Nano-Piezoelectricity in Barium Titanate." Nanoscience and Nanotechnology Letters 2, no. 1 (2010): 26–29. http://dx.doi.org/10.1166/nnl.2010.1048.

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Alfutimie, Abdullatif, Joanna S. Stevens, and Gordon Tiddy. "Gel phase nano formulation: The effect of triglycerides." Colloids and Surfaces A: Physicochemical and Engineering Aspects 516 (March 2017): 85–93. http://dx.doi.org/10.1016/j.colsurfa.2016.12.017.

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Dr., G. Nagaraju, Teena Lavdya, Sirisha V., and Hareesh Dara Dr. "FORMULATION AND EVALUATION OF CAPECITABINE LOADED NANO PARTICLES." Journal of Pharma Research 12, no. 6 (2023): 70–73. https://doi.org/10.5281/zenodo.14235266.

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<strong>Abstract</strong> <strong>N</strong>ano particles represent a promising drug delivery system of controlled and targeted drug release. They are specially designed to release the drug in the vicinity of target tissue. The aim of this study was toprepareandevaluatepolymethacrylicacidnanoparticlescontainingCapecitabineindifferent drug to polymer ratio by nano precipitation method. SEM indicated that nanoparticles have a discrete spherical structure without aggregation. The average particle size was found to be 121+8- 403 + 4 nm. The particle size of the nanoparticles was gradually increase
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Salah, Zeinab, Eman M. Abd El Azeem, Hanan F. Youssef, et al. "Effect of Tumor Suppressor MiR-34a Loaded on ZSM-5 Nanozeolite in Hepatocellular Carcinoma: In Vitro and In Vivo Approach." Current Gene Therapy 19, no. 5 (2019): 342–54. http://dx.doi.org/10.2174/1566523219666191108103739.

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Background: MicroRNA modulation therapy has shown great promise to treat hepatocellular carcinoma (HCC), however Efficient tissue-specific and safe delivery remains a major challenge. Objective: We sought to develop an inorganic-organic hybrid vehicle for the systemic delivery of the tumor suppressor miR-34a, and to investigate the efficiency of the delivered miR-34a in the treatment of HCC in vitro and in vivo. Methods: In the present study, pEGP-miR cloning and expression vector, expressing miR-34a, was electrostatically bound to polyethyleneimine (PEI), and then loaded onto ZSM-5 zeolite na
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Shrishail M Ghurghure, Priya L. Ingale, Anup A. Dhange, Akshay S Javalgikar, Rudramuni H Kore, and Dadagouda M Birajdar. "Itraconazole Self-Nano Emusifying Drug Delivery System for Enhancement of Solubility." Journal of Advanced Zoology 44, no. 5 (2023): 150–55. http://dx.doi.org/10.17762/jaz.v44i5.2577.

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The main objective of formulation is to enhance the bioavailability of the drug within the body. Some of the challenging subjects associated with poorly water-soluble drugs concern solubility and bioavailability factors. To overcome these problems, new technologies, such as lipid-based drug delivery systems including micro or nano emulsifying drug delivery system, have obtained importance in recent years, due to their enhanced solubility and bioavailability in the gastrointestinal tract. Such systems are solubilized within the lipid excipients or mixed with oils or surfactants/co-solvents to f
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Mohd Taib, Siti Husnaa, Siti Salwa Abd Gani, Mohamad Zaki Ab Rahman, Mahiran Basri, Amin Ismail, and Rosnah Shamsudin. "Formulation and process optimizations of nano-cosmeceuticals containing purified swiftlet nest." RSC Advances 5, no. 53 (2015): 42322–28. http://dx.doi.org/10.1039/c5ra03008k.

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The usage of purified swiftlet nest in nano-cosmeceuticals and response surface methodology in order to obtain the optimized formulation will be very beneficial and helpful to the swiftlet nest and nano-cosmeceuticals industries worldwide.
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Irfan, Muhammad, Mir Azam Khan, Aziz Ur Rehman, and Faiza Naureen. "Optimization of Lipid-Based Ketoconazole Nanoformulations Through Stirring Techniques and Ingredient Quantity Adjustments." Pharmaceutical Communications 3, no. 01 (2024): 35–44. https://doi.org/10.55627/pharma.003.001.0886.

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The Biopharmaceutical Classification System (BCS) classifies drugs on the basis of solubility and permeability. Ketoconazole belongs to class II drugs of the Biopharmaceutical Classification System (BCS) which are characterized by high permeability but low solubility issues. The current research work aimed to formulate optimized nano-formulation for ketoconazole by altering stirring time, speed, and ingredient ratios. In this study, a stirring speed minimum of 600 rpm and a maximum of 1200 rpm was used. The minimum stirring time of 7 minutes and a maximum of 30 minutes was noted. Olive oil was
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Fadzil, N. I., M. N. Mohd Rosmi, N. S. Wahid, et al. "Determining the Median Lethal Concentration (LC50) and Seedling Growth Effects of MARDI Nano-fertilizer on Rock melon (Cucumis melo)." Asian Journal of Plant Biology 5, no. 1 (2023): 43–47. http://dx.doi.org/10.54987/ajpb.v5i1.827.

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New fertilizer formulations and nitrogen delivery systems are needed to address deteriorating nutrient-use-efficiency and environmental hazards due to farmers' dependency on chemical fertilizers. Nanofertilizers (NF) made from tailored smart nano materials are a viable alternative to inefficient and harmful traditional fertilizers. Nanotechnology and NFs may help solve chemical fertilizers formulation difficulties. To boost rock melon yields, MARDI has created a nano-fertilizer made from nano-emulsions. The relations between seed germination inhibition (%) of rock melon seed and different conc
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Sreeharsha, Nagaraja, Samathoti Prasanthi, Satyavarapu Veera Venkata Naga Satya Mahalakshmi, et al. "Enhancement of Anti-Tumoral Properties of Paclitaxel Nano-Crystals by Conjugation of Folic Acid to Pluronic F127: Formulation Optimization, In Vitro and In Vivo Study." Molecules 27, no. 22 (2022): 7914. http://dx.doi.org/10.3390/molecules27227914.

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A brand-new nano-crystal (NC) version of the hydrophobic drug Paclitaxel (PT) were formulated for cancer treatment. A stable NC formulation for the administration of PT was created using the triblock co-polymer Pluronic F127. To achieve maximum entrapment effectiveness and minimal particle size, the formulation was improved using the central composite design by considering agitation speed and vacuum pressure at five levels (coded as +1.414, +1, 0, −1, and −1.414). According to the Design Expert software’s predictions, 13 runs were created and evaluated for the chosen responses. The formulation
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Padmanaban, Parivallal, and Punit R. Rachh. "Nanosuspension of Poorly Soluble Anti-Diabetic Drug for Enhancement of Solubility and Dissolution." Journal of University of Shanghai for Science and Technology 23, no. 11 (2021): 516–41. http://dx.doi.org/10.51201/jusst/21/11925.

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Canagliflozin is an anti-diabetic drug used in the adjuvant therapy for type-II diabetes as the inhibitor of sodium‐glucose co‐transporter-2 in the renal tubules. The poor solubility and permeability of the drug show limitations in the formulation development and therapeutic plasma concentration. The objective of the work was to improve the solubility and dissolution of the BCS class IV drug through surfactant stabilized nanosuspension formulation. Nanoparticles were developed by Nano precipitation-solvent evaporation method using Poly vinyl alcohol and Pluronic as surfactants at 1%, 3% and 5%
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Aini, Purnamasari Nur, Dzakwan Muhammad, Pramukantoro Ganet Eko, Mauludin Rachmat, and El Fahmi. "Formulation, Characterization and Antioxidant Myricetin Nanophytosome for Topical Delivery." Asian Journal of Pharmaceutical Research and Development 8, no. 3 (2020): 9–13. http://dx.doi.org/10.22270/ajprd.v8i3.718.

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Background: Phytosomes are recently introduced drug delivery system and novel botanical formulation to produce lipophilic molecular complex to improve absorption and bioavailability of phytoconstituent. Myricetin is a well-known flavonoid with different biological effects and contributed in food preserving by free radical scavenging activity. However, bioavailability of myricetin is an important limiting factor for its antioxidant activities. &#x0D; Purpose: To overcome this limitation, in the present study we aimed to produce myricetin-loaded nano phytosomes to improve its physicochemical sta
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Palesh S Rajkondawar and Amit B Patil. "Nano-sponges: A Novel Carrier for Delivery of Chemo-therapeutic Drugs." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 1040–44. http://dx.doi.org/10.26452/ijrps.v11i1.1933.

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Nano-sponges belong to the category of hyper-cross linked polymer which is based on the colloidal structure. Nano-sized carriers are developed recently and are being used to deliver poorly water soluble drug by modifying the pharmaco-kinetic parameter and provide enhanced prolonged release. As a new class of chemo-therapeutic agents is being developed, formulation is getting difficult to issues such as poor solubility, low loading capacity and less entrapment of the drug in the drug delivery system. Nano-sponges have shown to deliver the most complex and challenging Chemo therapeutic drugs due
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Kumar, Ranjeet, Vivek Kumar Patel, and Prof Rajeev Shukla. "Formulation Design and Characterization of Silver Sulfadiazine Loaded Nano Gel in the Treatment of Burn." International Journal of Research and Review 9, no. 7 (2022): 11–17. http://dx.doi.org/10.52403/ijrr.20220703.

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Background: In permeation of drug, size of drug plays a very important role as size of dug as much as smaller, it become very easy to permeate so that researchers attract towards making size in nano range. Silver sulfadiazine on of the drug which is very useful in the treatment of burn. Many processes are adapted to make nanoparticles of this drug but the promising method of preparation of NPs of this drug is still vacant. Objectives: Development of silver sulfadiazine loaded Nano gel by using Noveon polycarbophil AA-1 as gelling agent in the treatment of burn infections. Method: First of all,
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MA, Farrukh. "Formulation of Methotrexate Loaded Polymeric Zn-Nanoparticle: An Efficient Anti-Cancer Nano-Drug." Advances in Clinical Toxicology 5, no. 2 (2020): 1–8. http://dx.doi.org/10.23880/act-16000186.

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Bui, Van Cuong, The Tam Le, Tuyen Hong Nguyen, et al. "Curcumin-removed turmeric oleoresin nano-emulsion as a novel botanical fungicide to control anthracnose (Colletotrichum gloeosporioides) in litchi." Green Processing and Synthesis 10, no. 1 (2021): 729–41. http://dx.doi.org/10.1515/gps-2021-0071.

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Abstract During curcumin production in Vietnam, curcumin-removed turmeric oleoresin (CRTO) has been considered as a by-product. It costs to treat the by-product to prevent environmental pollution. In this study, the by-product was utilized as an active ingredient for preparing a botanical fungicide-based nano-emulsion and evaluated for its in vitro and in vivo control efficacy against Colletotrichum gloeosporioides, a causal agent of anthracnose of litchi, in the laboratory as well as a field trial. The nano-emulsion is colloidally stable and uniform with particle sizes of 95–250 nm. CRTO nano
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Prakash, Veda, and Lipika Parida. "Vitamin E encapsulated nano-emulsions formulation, rheological and antimicrobial analysis." Journal of Medical pharmaceutical and allied sciences 12, no. 3 (2023): 5820–25. http://dx.doi.org/10.55522/jmpas.v12i3.5019.

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Vitamin E is an important food ingredient that individuals ingest to help prevent numerous diseases. Nano-emulsions are frequently employed in pharmaceutical, food, and personal care applications as means of delivering a variety of lipophilic active substances, namely vitamins that are oil-soluble. Both high-energy and low-energy methods are used to create nano-emulsions. The latter, however, offers advantages including less cost, convenience of use, and increased energy efficiency. In this work, we used the emulsion phase inversion technique to create nano-emulsions containing vitamin E. We i
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Sarah, Nihal Shaikh, Namdev Dongare Suhani, R. Nehe Ashwini, and Shoheb Shaikh *Dr. "HARNESSING PHYTO-NANOTECHNOLOGY: A REVIEW ON PONGAMIA AND TURMERIC-INFUSED NANOEMULGELS FOR ANTIFUNGAL THERAPY." World Journal of Pharmaceutical Science and Research 4, no. 3 (2025): 326–37. https://doi.org/10.5281/zenodo.15607653.

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The present study focuses on the formulation and evaluation of a nano emulgel incorporating Pongamia pinnata seed extract and Curcuma longa (turmeric) for enhanced antifungal activity. Nano emulgels combine the benefits of nanoemulsion technology with gel- based topical delivery, offering improved drug solubility, skin permeability, and sustained release. Pongamia seed extract is known for its potent antifungal and wound-healing properties, while turmeric contributes strong anti-inflammatory and antimicrobial effects due to its curcumin content. The nanoemulsion was prepared using the aqueous
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Soni, Shalini, Rupal Babel, Sujata Saxena, A. Arputharaj, ASM Raja, and Meenu Srivastava. "Enhancing Cotton Fabric Softness and Wrinkle Resistance through Optimized Formulation of Nano ZnO and Benzalkonium Chloride-Enriched RinseCycle Softener." Ecology, Environment and Conservation 30, Suppl (2024): S431—S438. http://dx.doi.org/10.53550/eec.2024.v30i04s.072.

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This work attempts optimization of a multifunctional single rinse softener formulation for cotton fabric for domestic usage, catering to the growing customer demand for softeners with enhanced performance. Present section is part-I of the entire study. The primary objective is to determine the effects of optimized and developed formulation on softness and wrinkle resistance properties. We synthesized polyvinylpyrrolidone (PVP) stabilized nano-ZnO particles using the sol-gel method and characterized them using UV-VIS spectrophotometry, particle size analyser and X-ray diffraction. Atomic absorp
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Gaglio, Salvatore Calogero, Ylenia Jabalera, Manuel Montalbán-López, et al. "Embedding Biomimetic Magnetic Nanoparticles Coupled with Peptide AS-48 into PLGA to Treat Intracellular Pathogens." Pharmaceutics 14, no. 12 (2022): 2744. http://dx.doi.org/10.3390/pharmaceutics14122744.

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Among the strategies employed to overcome the development of multidrug-resistant bacteria, directed chemotherapy combined with local therapies (e.g., magnetic hyperthermia) has gained great interest. A nano-assembly coupling the antimicrobial peptide AS-48 to biomimetic magnetic nanoparticles (AS-48-BMNPs) was demonstrated to have potent bactericidal effects on both Gram-positive and Gram-negative bacteria when the antimicrobial activity of the peptide was combined with magnetic hyperthermia. Nevertheless, intracellular pathogens remain challenging due to the difficulty of the drug reaching th
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Guan, Feng, Qi Wang, Yongping Bao, and Yimin Chao. "Anti-rheumatic effect of quercetin and recent developments in nano formulation." RSC Advances 11, no. 13 (2021): 7280–93. http://dx.doi.org/10.1039/d0ra08817j.

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Venugopal, N. V. S., and N. V. S. Sainadh. "Synthesis and Characterization of Polymeric Nano-Formulation of Acephate." Nanoscience &Nanotechnology-Asia 7, no. 1 (2017): 58–61. http://dx.doi.org/10.2174/2210681207666161213102417.

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Xie, Jianlei, Yingwei Wang, Wonseok Choi, et al. "Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies." Chemical Society Reviews 50, no. 16 (2021): 9152–201. http://dx.doi.org/10.1039/d0cs01370f.

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Photodynamic therapy (PDT) has been extensively investigated for decades for tumor treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and immune activation ability.
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Srinidhi, K. R., V. M. Subrahmanyam, Angel Treasa Alex, A. Jesil Mathew, and B. Venkatesh Kamath. "Role of Nano-formulation in the treatment of Onychomycosis." Research Journal of Pharmacy and Technology 13, no. 1 (2020): 453. http://dx.doi.org/10.5958/0974-360x.2020.00088.8.

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Moghassemi, Saeid, Afra Hadjizadeh, Amirhossien Hakamivala, and Kobra Omidfar. "Growth Factor-Loaded Nano-niosomal Gel Formulation and Characterization." AAPS PharmSciTech 18, no. 1 (2016): 34–41. http://dx.doi.org/10.1208/s12249-016-0579-y.

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