Academic literature on the topic 'Natural neuroprotectants'

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Journal articles on the topic "Natural neuroprotectants"

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Sakshi, Jatale* Rupali Chopade Vedangi kulkarni Shivani Chavan Shatrughna Nagrik Dr. Shivshankar Mhaske. "Phytochemicals in Neurodegenerative Diseases: Natural Neuroprotectants." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4065–89. https://doi.org/10.5281/zenodo.15507301.

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Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD) pose significant challenges due to their progressive nature and lack of effective treatments. Phytochemicals, bioactive compounds derived from plants, have gained increasing attention for their neuroprotective properties, including antioxidant, anti-inflammatory, and anti-apoptotic effects. This review explores the role of key phytochemicals such as curcumin, resveratrol, quercetin, epigallocatechin gallate (EGCG), and ginsenosides in modulating cellular pathwa
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Babadjouni, Robin Moshe, Ryan E. Radwanski, Brian P. Walcott, et al. "Neuroprotective strategies following intraparenchymal hemorrhage." Journal of NeuroInterventional Surgery 9, no. 12 (2017): 1202–7. http://dx.doi.org/10.1136/neurintsurg-2017-013197.

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Intracerebral hemorrhage and, more specifically, intraparenchymal hemorrhage, are devastating disease processes with poor clinical outcomes. Primary injury to the brain results from initial hematoma expansion while secondary hemorrhagic injury occurs from blood-derived products such as hemoglobin, heme, iron, and coagulation factors that overwhelm the brains natural defenses. Novel neuroprotective treatments have emerged that target primary and secondary mechanisms of injury. Nonetheless, translational application of neuroprotectants from preclinical to clinical studies has yet to show benefic
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Muench, Gerald, Anton Rahmadi, Annette Maczurek, and Megan L. Steele. "O4-05-06: A versatile microglia-neuron co-culture system for the identification of anti-inflammatory neuroprotectants: Application to screening of natural compounds." Alzheimer's & Dementia 6 (July 2010): S158. http://dx.doi.org/10.1016/j.jalz.2010.05.493.

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Cliver, Richard N., Natalia Castro, Thais Russomano, et al. "Antioxidants Derived from Natural Products Reduce Radiative Damage in Cultured Retinal Glia to Prevent Oxidative Stress." Neuroglia 3, no. 3 (2022): 84–98. http://dx.doi.org/10.3390/neuroglia3030006.

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Retinal pathologies have been heavily studied in response to radiation and microgravity, including spaceflight-associated neuro-ocular syndrome (SANS), which is commonly developed in space flight. SANS has been characterized in clinical studies of astronauts returning to Earth and includes a range of symptoms, such as globe flattening, optic-disc edema, retinal folds, and retinal ischemia. In cases of retinal insult, Müller glia (MG) cells respond via neuroprotective gliotic responses that may become destructive to produce glial scarring and vison loss over time. Retinal pathology is further i
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Phung, Hung Manh, Sullim Lee, and Ki Sung Kang. "Protective Effects of Active Compounds from Salviae miltiorrhizae Radix against Glutamate-Induced HT-22 Hippocampal Neuronal Cell Death." Processes 8, no. 8 (2020): 914. http://dx.doi.org/10.3390/pr8080914.

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Oxidative stress is considered one of the factors that cause dysfunction and damage of neurons, causing diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), and Parkinson’s disease (PD).Recently, natural antioxidant sources have emerged as one of the main research areas for the discovery of potential neuroprotectants that can be used to treat neurological diseases. In this research, we assessed the neuroprotective effect of a 70% ethanol Salvia miltiorrhiza Radix (SMR) extract and five of its constituent compounds (tanshinone IIA, caffeic acid, salvianolic acid B, ro
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Rout, Sradhasini, Bandana Rath, Subrat Kumar Bhattamisra, Anjan Kumar, Ishani Rath, and Preetish Kumar Panigrahy. "Neuroprotective effect of methanolic extract of Sargassum wightii on rotenone-induced parkinsonism-like symptoms in Wistar albino rats." Journal of Herbmed Pharmacology 10, no. 4 (2021): 468–75. http://dx.doi.org/10.34172/jhp.2021.54.

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Introduction: The pathogenesis of Parkinson’s disease (PD) is multifactorial in which oxidative stress, neuroinflammation, and mitochondrial dysfunction are the leading factors. Currently, the antioxidant and anti-inflammatory agents of natural sources as neuroprotectants have raised much attention. The current study aimed to explore the neuroprotective effect of methanolic extract of Sargassum wightii in male Wistar albino rats against rotenone-induced PD. Methods: The rats were administered with rotenone (10 mg/kg orally) daily for 28 days to induce PD. S. wightii (200 mg/kg and 400 mg/kg) a
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Okeowo, Oritoke. "NEUROPROTECTANT ACTIVITY OF NATURAL COMPOUNDS IN STRESS." IBRO Neuroscience Reports 15 (October 2023): S49. http://dx.doi.org/10.1016/j.ibneur.2023.08.2153.

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Perusse, Dimitri, and Michael J. Smanski. "Stereoselective semi-synthesis of the neuroprotective natural product, serofendic acid." MedChemComm 10, no. 6 (2019): 951–60. http://dx.doi.org/10.1039/c9md00145j.

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Kesari, Kavindra Kumar, Anupam Dhasmana, Shruti Shandilya, et al. "Plant-Derived Natural Biomolecule Picein Attenuates Menadione Induced Oxidative Stress on Neuroblastoma Cell Mitochondria." Antioxidants 9, no. 6 (2020): 552. http://dx.doi.org/10.3390/antiox9060552.

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Several bioactive compounds are in use for the treatment of neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease. Historically, willow (salix sp.) bark has been an important source of salisylic acid and other natural compounds with anti-inflammatory, antipyretic and analgesic properties. Among these, picein isolated from hot water extract of willow bark, has been found to act as a natural secondary metabolite antioxidant. The aim of this study was to investigate the unrevealed pharmacological action of picein. In silico studies were utilized to direct the investigation towa
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Kaewkaen, Pratchaya, Terdthai Tong-un, Jintanaporn Wattanathorn, Supaporn Muchimapura, Wiroje Kaewrueng, and Sathaporn Wongcharoenwanakit. "Mulberry Fruit Extract Protects against Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/263520.

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Nowadays, the preventive strategy of vascular dementia, one of the challenge problems of elderly, has received attention due to the limitation of therapeutic efficacy. In this study, we aimed to determine the protective effect and possible mechanism of action of mulberry fruit extract on memory impairment and brain damage in animal model of vascular dementia. Male Wistar rats, weighing 300–350?g, were orally given mulberry extract at doses of 2, 10 and 50?mg/kg at a period of 7 days before and 21 days after the occlusion of right middle cerebral artery (Rt.MCAO). It was found that rats subject
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Dissertations / Theses on the topic "Natural neuroprotectants"

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Park, Han-A. "Natural Vitamin E, α-Tocotrienol, as a Neuroprotectant". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1291061955.

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Book chapters on the topic "Natural neuroprotectants"

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Kumar, Anil, Manveen Bhardwaj, and Harshpreet Kaur. "Possible Role of Neuroprotectants and Natural Products in Epilepsy: Clinical Aspects and Mode of Action." In Neuroprotective Natural Products. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527803781.ch9.

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Brimson, James Michael, and Tewin Tencomnao. "Medical potentials of natural neuroprotectants derived from herbal extracts and their phytochemicals." In Natural Molecules in Neuroprotection and Neurotoxicity. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-23763-8.00005-1.

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Patel, Radhika Pooja, Ehtesham Shamsher, Daniel Hill, and Maria Francesca Cordeiro. "Naturally occurring neuroprotectants in glaucoma." In Progress in Brain Research. Elsevier, 2020. http://dx.doi.org/10.1016/bs.pbr.2020.06.022.

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