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Relevant bibliographies by topics / Nephroprotective Activity [1]

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Academic literature on the topic 'Nephroprotective Activity [1]'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Nephroprotective Activity [1]"

1

Bhusnar, Hanumant, Sushil Patil, Soma Das, and Laxmikant Borse. "Network Pharmacology Approach to Evaluate the Therapeutic Effects of Caesalpinia bonduc (L.) Components for the Nephroprotective Activity." Innovation of Chemistry & Materials for Sustainability 2, no. 1 (2025): 23–31. https://doi.org/10.63654/icms.2025.02023.

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Caesalpinia bonduc (L.) (Family: Caesalpiniaceae) commonly known as Bonduc Nut and Fever Nut is the main ingredients in Hjam-hbras formulation, a single herb formulation documented in Buddha Shakamuni for treating renal diseases. C. bonduc seed extract is also scientifically validated for having renal protective effects but its exact mechanism by which it showed renal protective effect is still unknown. In this study, we aimed to evaluate the nephroprotective mechanism of action of C. bonduc seed by performing Network pharmacology analysis. ADMET property analysis reveals 21 out of 190 phytoch

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2

Afroz, Mehdi and Dr. Fazil ahmad. "NEPHROPROTECTIVE ACTIVITYOF ACORUS CALAMUS LEAVES EXTRACT AGAINST LITHIUM INDUCED NEPHROTOXICITY IN WISTAR RATS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 3132–43. https://doi.org/10.5281/zenodo.1237980.

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Acorus calamus is a tall perennial herb. It is a wetland monocot of the Acoraceae family, in the genus Acorus.It is also called sweet flag or calamus. Sweet Sedge is 30 to 100 cm tall. Tufts of basal leaves arises from a spreading rhizome. Calamus is used as sedative, diuretic, laxative and as a carminative agent in modern herbal science medicines. Its use in siddha and ayurvedic medicine is also reported where in stems, leaves, roots, barks plays magnificent role. Few uses approved for calamus is as a flavour for pipe tobacco from the rhizome essence and is also used as essential oil in perfu

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3

Aljutaily, Thamer, Sarah M. Almutairi, and Hend F. Alharbi. "The Nephroprotective Potential of Brassica nigra Sprout Hydroalcoholic Extract against Carbon Tetrachloride-Induced Renal Toxicity in Rats." Foods 12, no. 21 (2023): 3906. http://dx.doi.org/10.3390/foods12213906.

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The nephroprotective potential of the Brassica nigra sprout (BNS) hydroalcoholic extract against carbon tetrachloride (CCl4)-induced renal toxicity in rats was the object of this study. B. nigra sprouts were prepared in the lab to monitor the bio-changes in bioactive compounds during the sprouting for up to 7 days at 17 ± 1 °C and 90% relative humidity. Subsequently, 6-day sprouts of B. nigra were selected according to their phenolics and antioxidant activity, extracted, and examined for their nephroprotective and antioxidative stress potential at 250 and 500 mg sprout extracts kg−1 bw, in viv

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4

Afjal, MA, SA Hasan Abdi, S. Sharma, et al. "Anti-inflammatory role of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl) in nephroprotection." Human & Experimental Toxicology 38, no. 6 (2019): 713–23. http://dx.doi.org/10.1177/0960327119836203.

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Inflammation is one of the mechanisms involved in the acute kidney injury (AKI) caused by cisplatin (CP)-induced nephrotoxicity. Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl) has powerful antioxidant activity. We investigated its potential nephroprotective effects and the underlying mechanisms that may add further benefits to its clinical usefulness in a CP-induced AKI model. Male Swiss albino mice were divided randomly into four groups: control, CP (20 mg/kg intraperitoneally), tempol (100 mg/kg/day, per os) + CP, and tempol only treatments. Blood samples were collected to analyze re

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5

Rosnizar, Nyoman Ehrich Lister I, Edy Fachrial, Shahna, and Sukirman Lie. "Nephroprotective effect of mengkudu (Morinda citrifolia) on rats induced by doxorubicin." Journal of Inventions in Biomedical and Pharmaceutical Sciences 5, no. 2 (2020): 10–17. http://dx.doi.org/10.26452/jibps.v5i2.1437.

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Chronic kidney disease in the world is currently experiencing an increase and become a serious health problem. Doxorubicin clinical efficacy is hampered by dose-related organotoxic (heart, liver, and kidney) potential. The purpose of this study was to determine the nephroprotective activity of mengkudu fruit ethanol extract against the rats induced by doxorubicin. Mengkudu fruit ethanol extract was obtained by maceration. Nephroprotective activity test is done by measuring urea and creatinine. Animals were induced with doxorubicin (DOX) 5 mg/kgbw on day 1, 7, 14 and 20th. Administration of men

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6

Rosita, Rosita, Yuandani Yuandani, and Marianne Marianne. "NEPHROPROTECTIVE ACTIVITY OF ETHANOL EXTRACT OF CURCUMA MANGGA VAL. IN PARACETAMOL-INDUCED MALE MICE." Asian Journal of Pharmaceutical and Clinical Research 11, no. 13 (2018): 126. http://dx.doi.org/10.22159/ajpcr.2018.v11s1.26585.

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Objective: This study aimed to evaluate nephroprotective activity of Curcuma mangga in paracetamol-induced male mice.Methods: Male mice were divided into several groups including normal control, negative, positive, and treatment groups. Treatment groups were orally administered with C. mangga extract at doses of 100, 200, and 400 mg/kg bw for 7 days. On day 7after 1 h of treatment, the mice were induced with paracetamol 1.05 g/kg bw. Serum creatinine level measurement and histopathotlogy study were performed at the end of experiment.Results: C. mangga extract was able to inhibit the increase o

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7

Zhou, Lu, Peng Yu, Ting-ting Wang, et al. "Polydatin Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting Ferroptosis." Oxidative Medicine and Cellular Longevity 2022 (January 15, 2022): 1–14. http://dx.doi.org/10.1155/2022/9947191.

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Cisplatin is widely used in the treatment of solid tumors, but its application is greatly limited due to its nephrotoxicity; thus, there is still no effective medicine for the treatment of cisplatin-induced acute kidney injury (Cis-AKI). We previously identified that polydatin (PD) exerts nephroprotective effects by antioxidative stress in AKI models. Recent evidence suggests that oxidative stress-induced molecular events overlap with the process of ferroptosis and that there are common molecular targets, such as glutathione (GSH) depletion and lipid peroxidation. Nevertheless, whether the nep

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8

Shiyan, Shaum, Herlina Herlina, and Lita Rizkika Sari. "NEPHROPROTECTIVE OF ANTHOCYANIN PIGMENTS EXTRACT FROM RED CABBAGE (BRASSICA OLERACEA L. VAR. CAPITATA F. RUBRA) AGAINST GENTAMICIN-CAPTOPRIL-INDUCED NEPHROTOXICITY IN RATS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 4 (2018): 432. http://dx.doi.org/10.22159/ajpcr.2018.v11i4.20373.

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Objective: Red cabbage (Brassica oleracea L. var. Capitata f. rubra) has a fairly high anthocyanin content and is a source of powerful antioxidants. This study is basic for the development of a nutraceutical, which has nephroprotective activity.Methods: Red cabbage was extracted using ethanol and water with a mixture of citric acid with a variation of 1, 2, and 3%. The total anthocyanin was determined with pH-differential method. The Wistar strain male rats were divided into five groups. Group 1 as a negative control, Group 2 as a positive control treated with Vitamin E dose of 400 mg/kg BW da

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9

Heeba, Gehan H., Marwa A. M. Ali, and Azza A. K. El-Sheikh. "Rosuvastatin Induces Renal HO-1 Activity and Expression Levels as a Main Protective Mechanism against STZ-Induced Diabetic Nephropathy." Medicina 58, no. 3 (2022): 425. http://dx.doi.org/10.3390/medicina58030425.

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Background and Objectives: Nephroprotective effect of statins is still controversial. The aim of this study was to investigate the possible hemin-like nephroprotective effect of rosuvastatin (RSV) in streptozotocin (STZ)-induced diabetic rats. Materials and Methods: DN was induced in rats via a single dose of 50 mg/kg STZ i.p., with or without RSV (10 mg/kg orally) for 30 days. To investigate hemin-like effect of RSV on renal heme oxygenase-1 (HO-1), RSV was administered in the presence or absence of an inhibitor of HO-1; zinc protoporphyrin-XI (ZnPP), in a dose of 50 µmol/kg i.p. Results: Ind

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10

Sultana, Mst Shahin, Rekha Rani Saha, Sheikh Nazrul Islam, Tasnin Afrin, Rumana Afroz, and Mahbuba Jahan Lotus. "Nephroprotective Activity of Aqueous Extract of Carica Papaya Seeds in Carbon Tetrachloride Induced Nephrotoxic Rats." Ibrahim Cardiac Medical Journal 12, no. 1 (2023): 9–17. http://dx.doi.org/10.3329/icmj.v12i1.69540.

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Background & objective: The kidney plays a dominant role in homeostasis by excreting the metabolic waste products and excess of necessary substances. It is a major excretory organ regulating water and electrolyte balance and conserving necessary products according to body needs. Nephrotoxicity is one of the most common kidney problems. A number of therapeutic agents can adversely affect the kidney resulting in acute renal failure, chronic interstitial nephritis and nephritic syndrome. Nephroprotective agents are the substances which possess protective activity against Nephrotoxicity. Early

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