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Dissertations / Theses on the topic 'Nephthea'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Ahmed-Mohamed, Youssef [Verfasser]. "Die Göttin Nephthys (Nebethut) : Entstehung und Entwicklung einer ägyptischen Gottesvorstellung bis zum Ende des Neuen Reiches / Youssef Ahmed-Mohamed." Aachen : Shaker, 2016. http://d-nb.info/1104047969/34.

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2

Weng, Yu-Lin, and 翁玉玲. "Cytotoxic Constituents from Formosan Soft Coral Nephthea brassica." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/57459344770468382213.

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碩士<br>國立中山大學<br>海洋資源研究所<br>86<br>The methylene chloride extract of Formosan soft coral Nephthea brassica (colle-cted in Liu Chiu Yu) was found to exhibit significant cytotoxicity against sev-eral cancer cell lines. Cytotoxicity-guided fractionation led to the isolati-on of six cembranoid diterpenes and three sesquiterpenes. They are nephthenol(1), cembrene-A(3), epoxycembrene-A(23), 2-hydroxynephthenol(52),(-)-β-elemene(55), (-)-selin-11-en-4α-ol(56) and compounds 51,53,54. Compounds 51,53 and 54were isolated from natural sources for the first time. Compounds 1,3,23,52 and53 exhibited signific

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3

Puu, Shyh-Yueh, and 浦仕岳. "Chemical Constituents of the Formosan Soft Coral Nephthea chabrolii." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/17559921418023241046.

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碩士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>101<br>Numerous bioactive secondary metabolites including sesquiterpenoids,diterpenoids, meroditerpenoids, and steroids have been isolated from the soft corals of the genus Nephthea. In order to search for novel bioactive substances from marine organisms, we have investigated the secondary metabolites of the organic extract of the soft coral Nephthea chabrolii collected at San-Hsian-Tai. Chromatographic fractionation of the acetone-soluble has led to the isolation of four 19-oxygenated steroids 1–4 and two 19-norergosterols 5, 6, along with twelve known compou

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4

Chou, Shih-Kai, and 周詩凱. "Studies on steroids from the Formosan soft coral Nephthea erecta." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/53292955986069659374.

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碩士<br>義守大學<br>生物科技學系<br>104<br>Steroids are some of the most frequently encountered metabolites in soft corals of the genus Nephthea. Of particular interest, steroids have been reported to diplay diverse biological activity, including antitumor, anti-inflammatory and antifouling. Our recent study on the bioactive matabolites derived from the soft coral Nephthea erecta, resulted in the isolation of a new 10-demethylated steroids, nephtheasteroid A (1), a new 19-oxygenated steroid, nephtheasteroid B (2), as well as five known metabolites, 3－6. The structure was determined by means of IR, MS, and

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5

Whuang, Ta-Yuan, and 黃大原. "Studies on the Chemical Constituents from the Formosan Octocoral Nephthea columnaris." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/87242723143689962986.

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碩士<br>國立東華大學<br>海洋生物研究所<br>105<br>Studies on the chemical constituents of a Taiwanese soft coral Nephthea columnaris have led to the isolation of eleven compounds, including ten sterols and one cembrane-type compound. Among these isolated natural products, there were three new compounds, columnaristerols A-C (1-3), and eight known compounds, litosterol (4), 24-methylenecholesterol (5), 24-methylene-cholest-5-ene-3β,7α-diol (6), 5,8α-epidioxy-5α-ergosta-6,24(28)-dien-3β-ol (7), 4α-methylergosta-22(E),24(28)-dien-3β-ol (8), 24-methylcholesta-5,24(28)-diene-3β,19-diol-7-one (9), 5,6-epoxylitoster

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6

CHEN, JIUN-HUNG, and 陳俊宏. "Studies on the Secondary Metabolites from the Soft Coral Nephthea chabroli." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/98023460083435095031.

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碩士<br>國立高雄大學<br>生命科學系碩士班<br>104<br>In order to research for bioactive secondary metabolites, we have investigated the chemical constituents of the Formosan soft coral Nephthea chabroli collected at Tsau-Lou-Cho Island of Taiwan. The soft coral N. chabroli was found to contain numerous distinct skeletons of metabolites, mainly containing diterpenoids, sesquiterpenoids and steroids. The investigation resulted in the purification of 19 compounds, comprising two new 19-norergosterols, 19-norergosta-5,24(28)-dien-3β,10β-diol (1) and 10β-hydroxy-19-norergosta-5,24(28)-dienyl 3β-acetate (2), two new

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7

Lin, Fang-yi, and 林芳儀. "Studies on the Natural Products of the Formosan Soft Coral Nephthea chabrolii." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/26830251922665191473.

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碩士<br>國立中山大學<br>海洋資源學系研究所<br>93<br>Investigation on the chemical constituent of a Formosan soft coral Nephthea chabrolii, collected along the coast off Kenting, has led to the isolation of nine marine natural products (1–9), including seven new compounds, chabrolosteroids A–G (1–7), and two known compounds, loliolide (8) and teuhetenone A (9). The structures of 1–9 were determined on the basis of spectroscopic analyses, including MS, IR, 1D NMR, and 2D NMR. Cytotoxicities of 1–9 against selected cancer cell lines were also measured.

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8

Hsiao, Ting-Hsi, and 蕭鼎曦. "Studies on the Chemical Constituents from the Cultured Soft Coral Nephthea columnaris." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/64649857209425874800.

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碩士<br>國立東華大學<br>海洋生物研究所<br>103<br>In the studies on the chemical constituents of the cultured soft coral Nephthea columnaris had led to the isolation of six cembrane -type diterpenoids and six steroids, including four new compounds, columnariols A and B (1 and 2), 2β-hydroxy-11α,12β-epoxynephthenol (3) and 2β-hydroxy-7β,8α-epoxynephthenol (4), a new natural compound 5 along with seven know compounds, epoxynephthenol (5), nephthenol (6), nephalsterol (7), 5α,8α-epidioxy-24methylcholesta-6,24(28)-dien-3β-ol (8), 3β-hydroxy-24-methylene-5-cholesten-7-one (9), 24-methylenecholesterol (10), litost

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9

Siao, Shu-Sheng, and 蕭樹昇. "Paralemnalia digitiformis and Nephthea Chabroli, as well as Brown Alga Homoeostrichus formosana." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/74251878535443906611.

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碩士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>104<br>In order to search for bioactive compounds, we have studied the chemical constituents from the organic extracts of Formosan soft corals Paralemnalia digitiformis and Nephthea chabroli as well as Formosan brown alga Homoeostrichus formosana. Chromatographic frctionation of the organic solubles of Paralemnalia digitiformis has led to isolation of a new neolemnane type sesquiterpene (1) and a known compound, nardosinane type-sesquiterpenoid (2). Chromatographic purification of the organic solubles of Homoeostrichus formosana has led to the isolation of six

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10

Huang, Ya-Ching, and 黃雅靖. "Chemical Constituents and Anti-inflammatory Activity Studies of Formosan Soft Coral Nephthea chabrolii." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/v5yxys.

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碩士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>96<br>Soft corals belonging to the genus Nephthea have been found to be a rich source of terpenoids and steroids. Chromatographic separation of acetone and CH2Cl2/MeOH extracts of Formosan soft coral Nephthea chabrolii resulted in the isolation of thirteen new steroids, including nine 4α-methylated steroids (1−6, 8−10), three 19-oxygenated steroids (11−13), and a novel skeleton 19-norsteroid (7). The structures of these metabolites were elucidated by extensive spectral analyses and anti-inflammatory activities were measured in vitro. Compounds 1−2, 4−5, 7−11 a

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11

Chao, Wei-Chuan, and 趙煒銓. "Studies on the secondary metabolites from the soft corals Nephthea chabroli and Cespitularia caerulea." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/va8f65.

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碩士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>106<br>Soft corals belonging to the genera Nephthea and Cespitularia have proven to be a rich source of bioactive steroids and terpenoids. N. chabroli collected from Hsiao Liouciou and C. caerulea collected from Green island were studied in this thesis. Three new steroids (1‒3) and one known steroid (4) were isolated from Nephthea chabroli, including one 19-oxygenated sterol (1), one polyoxygenated sterol (2), one 3β-oxygenated sterol (3) and one known 3β-oxygenated sterol (4). One known eudesmane-type sesquiterpene (5), four known verticillene-type diterpenes

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12

Chiou, Jiunn-Chin, and 邱俊欽. "Chemical Constituents and Cytotoxicity of Formosan Soft Corals Sinularia granosa, Sarcophyton crassocaule and Nephthea erecta." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/16115243650824894135.

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碩士<br>國立中山大學<br>海洋資源學系<br>87<br>Chromatographic purification of a cytotoxic chloroform extract of Formosan soft coral Sinularia granosa (collected in Green Island) led to the isolation of two known norcembrane norditerpenoids, (1R*, 5S*, 8R*, 10S*, 11R*)—11—hydroxy—1—isopropenyl—8—methyl—3, 6—dioxo—5, 8—epoxy—cyclotetradec—12—ene—10, 12－carbolactone (45) and (1R*, 5S*, 8R*, 10S*, 11S*)—11—hydroxy—1—isopropenyl—8—methyl—3, 6—dioxo—5, 8—epoxy—cyclotetradec—12—ene—10, 12－carbolactone (46). Purification of a dichloromethane extract of Formosan soft coral Sarcophyton crassocule (collecte

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13

Liu, Kuan-Ming, and 劉冠茗. "Studies on the Chemical Constituents from the Formosan Soft Corals Sarcophyton trocheliophorum and Nephthea chabrolii." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/11957681107839013420.

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碩士<br>國立東華大學<br>海洋生物研究所<br>103<br>Studies on the secondary metabolites from the soft coral, Sarcophyton trocheliophorm, collected off the coast of Orchid Island, Taiwan, have led to the isolation of three cembrane analogues, including two new cembranes, trocheliolides A (1) and B (2), and a known cembrane, (+)-isosarcophine (3). In addition, the soft coral, Nephthea chabrolii, collected off the coast of Southern Taiwan, yielded three known compounds, including a sterol, 24-methylenecholesterol (4), and two benzoquinone derivatives, chabrolohydroxybenzoquinone A (5) and 2,7-dimethyl-2-[E,E]-4',

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14

Cheng, Shi-Yie, and 鄭旭益. "Studies on the Secondary Metabolites from the Soft Corals Nephthea erecta, Lobophytum durum, and Sarcophyton ehrenbergi." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/26921914020836391117.

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博士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>97<br>In order to search for novel bioactive compounds, we have investigated the secondary metabolites of the soft corals Nephthea erecta, Lobophytum durum, and Sarcophyton ehrenbergi. Chemical examinations on the organic extracts of N. erecta, have resulted in the isolation of six new sesquiterpenoids (1-6), a new calamenene-type sesquiterpene with a mercaptan group, erectathiol (7), a new tri-nor-eudesmadienone (8), two known sesquiterpenoids (9 and 10), one novel seco-germacrane sesquiterpene (11), three unexpected artificial 19-oxygenated steroids (12-14),

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15

Su, Jui-hsin, and 蘇瑞欣. "Studies on the Natural Products from the Formosan Soft corals Nephthea chabrolii, Sinularia manaarensis, Sinularia leptoclados, and Gorgonian Briareum sp." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/71950661877165177615.

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博士<br>國立中山大學<br>海洋生物科技暨資源學系研究所<br>94<br>In order to discover and develop new drug from soft corals and gorgonian corals of Taiwan, we have searched the bioactive metabolites from the organic extracts of three soft corals Nephthea chabrolii, Sinularia manaarensis, Sinularia leptoclados, and one Gorgonian of Briareum genus. This study had led to the isolation of fifty-five natural products (1–55), including seventeen new meroditerpenoid-related metabolites (1–7 and 9–18), two new C18 terpenoid–related carboxylic acids (20 and 21), three new sesquiterpenoidalnatural products (22–24), and two new

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