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Journal articles on the topic 'Nephthea'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

van Ofwegen, L. P., and D. S. J. Groenenberg. "A centuries old problem in nephtheid taxonomy approached using DNA data (Coelenterata: Alcyonacea)." Contributions to Zoology 76, no. 3 (2007): 153–78. http://dx.doi.org/10.1163/18759866-07603002.

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The current centuries old classification of the family Nephtheidae is still mostly based on colony morphology. In this family the Indo-Pacifc genera Litophyton, Nephthea, Dendronephthya and Stereonephthya, and the Atlantic genus Neospongodes form a complex mix of closely related, poorly described species which cannot be recognized using only colony morphology. Attempts with the more modern approach of comparing skeleton composition (sclerites) have been only partly successful because of the extreme variation of sclerite forms present in these genera. The genus Chromonephthea Van Ofwegen, 2005,

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2

Fahrudin, Fahri, Dinda Rama Haribowo, Rahmi Karmila, Danang Aji Pangestu, and Fathin Hamida. "Identifikasi Metabolit Sekunder dan Aktivitas Antioksidan Karang Lunak Nephthea sp. Hasil Transplantasi Secara In Situ dan Ex Situ." Al-Kauniyah: Jurnal Biologi 17, no. 1 (2023): 238–46. http://dx.doi.org/10.15408/kauniyah.v17i1.35781.

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AbstrakKarang lunak (Nephthea sp.) menghasilkan metabolit sekunder di habitat aslinya dan dapat dikembangkan menjadi marine natural product (MNP). Nephthea sp. hasil transplantasi diharapkan juga menghasilkan metabolit sekunder yang sama. Tujuan penelitian ini adalah melakukan identifikasi metabolit sekunder secara kualitatif dan kuantitatif pada Nephthea sp. hasil transplantasi serta menguji aktivitas antioksidannya. Sampel Nephthea sp. berasal dari Taman Nasional Ujung Kulon (in situ) dan dari akuarium sebagai sampel transplantasi ex situ. Kedua sampel diekstraksi dengan maserasi menggunakan

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3

van, Ofwegen Leen. "The genus Litophyton Forskål, 1775 (Octocorallia, Alcyonacea, Nephtheidae) in the Red Sea and the western Indian Ocean." ZooKeys 567 (February 22, 2016): 1–128. https://doi.org/10.3897/zookeys.567.7212.

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The Litophyton species of the Red Sea and the western Indian Ocean are revised, which includes species previously belonging to the genus Nephthea, which is synonymized with Litophyton. A neotype for both Litophyton arboreum, the type species of Litophyton, and Nephthea chabrolii, the type species of Nephthea, are designated. The new species L. curvum sp. n. is described and depicted, and a key to all Litophyton species is provided. Of the 26 species previously described from the western Indian Ocean and Red Sea, 13 species are considered valid and 13 have been synonymized or placed in other ge

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4

Syamsu, Andi Mu'nisa, Andi Faridah Arsal, A. Muflihunna, and Adlillah Triastuti. "Efektivitas Ekstrak Etanol Karang Lunak (Nephthea sp.) terhadap Gambaran Histopatologi Paru-Paru Mencit (Mus musculus)." Sainsmat : Jurnal Ilmiah Ilmu Pengetahuan Alam 11, no. 2 (2022): 104. http://dx.doi.org/10.35580/sainsmat112330232022.

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Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol karang lunak (Nephthea sp.) terhadap gambaran histopatologi paru mencit (Mus musculus). Jenis penelitian ini adalah eksperimental. Karang lunak diekstrak dengan menggunakan etanol 95% sehingga diperoleh ekstrak kental. Tigapuluh ekor mencit dibagi dalam enam kelompok perlakuan dan 3 ulangan, kelompok kontrol negatif hanya diberi pakan standar, kelompok kontrol positif diberi paparan HCl 37% selama 10 hari, kelompok preventif 1 dan 2 diberi ekstrak karang lunak masing-masing 0,5g dan 1g secara oral pada hari ke 8 sebelu

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5

Cheng, Shi-Yie, Ya-Chiang Huang, Zhi-Hong Wen, et al. "Novel sesquiterpenes and norergosterol from the soft corals Nephthea erecta and Nephthea chabroli." Tetrahedron Letters 50, no. 7 (2009): 802–6. http://dx.doi.org/10.1016/j.tetlet.2008.12.002.

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6

A, S. R. ANJANEYULU, and V. S. PRAKASH C. "An uncommon 14-Methyldihydroxy Steroid from the Soft Coral Nephthea chabroli of Indian Coast1." Journal of Indian Chemical Society Vol. 71, June-Aug 1994 (1994): 523–25. https://doi.org/10.5281/zenodo.5895979.

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School of Chemistry, Andhra University, Visakhapatnam-530 003 <em>Manuscript received 9 February 1994</em> An uncommon 14-Methyldihydroxy Steroid from the Soft Coral Nephthea chabroli of Indian Coast<sup>1</sup>

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7

Whuang, Ta-Yuan, Hong-Chieh Tsai, Yin-Di Su, Tsong-Long Hwang, and Ping-Jyun Sung. "Sterols from the Octocoral Nephthea columnaris." Marine Drugs 15, no. 7 (2017): 212. http://dx.doi.org/10.3390/md15070212.

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8

Abdelhafez, Omnia Hesham, John Refaat Fahim, Ramy R. El Masri, et al. "Chemical and biological studies on the soft coral Nephthea sp." RSC Advances 11, no. 38 (2021): 23654–63. http://dx.doi.org/10.1039/d1ra03045k.

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The cytotoxic potential of the crude extract, different fractions, and green synthesized nanoparticles of the soft coral Nephthea sp. was studied, supported by LC-HR-ESI-MS metabolomics analysis and molecular docking of the dereplicated compounds.

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9

Lin, Chin-Cheng, Ta-Yuan Whuang, Jui-Hsin Su, Tsong-Long Hwangd, Ya-Chang Wu та Ping-Jyun Sung. "4α-Methylergosta-22(E),24(28)-dien-3β-ol, a New Marine Sterol from the Octocoral Nephthea Columnaris". Natural Product Communications 12, № 3 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200308.

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A new marine sterol, 4α-methylergosta-22( E),24(28)-dien-3β-ol (1), was isolated from the octocoral Nephthea columnaris. The structure of 1 was elucidated on the basis of spectroscopic and mass spectrometric methods.

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10

Mehta, G., Y. Venkateswarlu, M. Rama Rao та R. Uma. "A Novel 4α-Methyl Sterol from the Soft Coral Nephthea chabroli". Journal of Chemical Research 23, № 10 (1999): 628–29. http://dx.doi.org/10.1177/174751989902301021.

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A new sterol, 4α-methyl-24-methylene-5α-cholestan-3β,8β-diol (1) and three known sterols 4α-methyl-24-methyl-enecholestan-3β-ol, 4α-methylcholestan-3β-ol and 24-methylenecholest-4-en-3-one are isolated from the soft coral Nephthea chabroli and characterized through spectral data and in the case of 1 by X-ray crystallographic analysis.

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11

Mohamed, Tarik A., Abdelsamed I. Elshamy, Mahmoud A. A. Ibrahim, et al. "Gastroprotection against Rat Ulcers by Nephthea Sterol Derivative." Biomolecules 11, no. 8 (2021): 1247. http://dx.doi.org/10.3390/biom11081247.

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Different species belonging to the genus Nephthea (Acyonaceae) are a rich resource for bioactive secondary metabolites. The literature reveals that the gastroprotective effects of marine secondary metabolites have not been comprehensively studied in vivo. Hence, the present investigation aimed to examine and determine the anti-ulcer activity of 4α,24-dimethyl-5α-cholest-8β,18-dihydroxy,22E-en-3β-ol (ST-1) isolated from samples of a Nephthea species. This in vivo study was supported by in silico molecular docking and protein–protein interaction techniques. Oral administration of ST-1 reduced ra

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12

Wang, Shang-Kwei, Shyh-Yueh Puu, and Chang-Yih Duh. "New Steroids from the Soft Coral Nephthea chabrolii." Marine Drugs 11, no. 12 (2013): 571–80. http://dx.doi.org/10.3390/md11020571.

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13

Su, Jui-Hsin, Fang-Yee Lin, Ho-Cheng Huang, et al. "Novel steroids from the soft coral Nephthea chabrolii." Tetrahedron 63, no. 3 (2007): 703–7. http://dx.doi.org/10.1016/j.tet.2006.10.082.

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14

Hsiao, Ting-Hsi, Ching-Hsiao Cheng, Tung-Ying Wu, et al. "New Cembranoid Diterpenes from the Cultured Octocoral Nephthea columnaris." Molecules 20, no. 7 (2015): 13205–15. http://dx.doi.org/10.3390/molecules200713205.

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15

Wang, Shang-Kwei, and Chang-Yih Duh. "Nardosinane Sesquiterpenoids from the Formosan Soft Coral Nephthea elongata." CHEMICAL & PHARMACEUTICAL BULLETIN 55, no. 5 (2007): 762–65. http://dx.doi.org/10.1248/cpb.55.762.

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16

El-Gamal, Ali Ali Hassan, Shang-Kwei Wang, and Chang-Yih Duh. "Prenylbicyclogermacrane Diterpenoids from the Formosan Soft Coral Nephthea elongata." CHEMICAL & PHARMACEUTICAL BULLETIN 55, no. 6 (2007): 890–93. http://dx.doi.org/10.1248/cpb.55.890.

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17

Ishii, Takahiro, Hiroshi Matsuura, Zhan Zhaoqi, and Charles Santhanaraju Vairappan. "A New Norsesquiterpenoid from a Bornean Soft Coral Genus Nephthea." Molecules 14, no. 11 (2009): 4591–96. http://dx.doi.org/10.3390/molecules14114591.

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18

Wang, Shang-Kwei, Shyh-Yueh Puu, and Chang-Yih Duh. "New 19-Oxygenated Steroids from the Soft Coral Nephthea chabrolii." Marine Drugs 10, no. 12 (2012): 1288–96. http://dx.doi.org/10.3390/md10061288.

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19

Ishii, Takahiro, Takashi Kamada, and Charles S. Vairappan. "Three new cembranoids from the Bornean soft coral Nephthea sp." Journal of Asian Natural Products Research 18, no. 5 (2016): 415–22. http://dx.doi.org/10.1080/10286020.2016.1145670.

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20

Cheng, Shi-Yie, Shang-Kwei Wang, Zhi-Hong Wen, Chang-Feng Dai, and Chang-Yih Duh. "Three new eudesmanoids from the Formosan soft coral Nephthea erecta." Journal of Asian Natural Products Research 11, no. 11 (2009): 967–73. http://dx.doi.org/10.1080/10286020903282806.

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21

Su, Jui-Hsin, Chang-Feng Dai, Hsin-Hui Huang, et al. "Terpenoid-Related Metabolites from a Formosan Soft Coral Nephthea chabrolii." CHEMICAL & PHARMACEUTICAL BULLETIN 55, no. 4 (2007): 594–97. http://dx.doi.org/10.1248/cpb.55.594.

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22

Hassan, Nevine H., Seham S. El-Hawary, Mahmoud Emam, et al. "Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies." Pharmaceuticals 16, no. 7 (2023): 957. http://dx.doi.org/10.3390/ph16070957.

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This study shed light for the first time on the in vivo diabetic wound healing potential activity of natural marine soft coral polymeric nanoparticle in situ gel using an excision wound model. A Nephthea sp. methanol–methylene chloride extract loaded with pectin nanoparticles (LPNs) was created. For the preparation of in situ gel, ion-gelation techniques, the entrapment efficiency, the particle size, the polydispersity index, the zeta potential, the in-vitro drug release, and a transmission electron microscope were used and the best formula was selected. Using (UPLC-Q/TOF-MS), 27 secondary met

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23

Ishii, Takahiro, Zhan Zhaoqi, and Charles Santhanaraju Vairappan. "A New Cembrane Diterpene from the Bornean Soft Coral Nephthea sp." Molecules 15, no. 6 (2010): 3857–62. http://dx.doi.org/10.3390/molecules15063857.

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24

Hsiao, Ting-Hsi, Chun-Sung Sung, Yu-Hsuan Lan, et al. "New Anti-Inflammatory Cembranes from the Cultured Soft Coral Nephthea columnaris." Marine Drugs 13, no. 6 (2015): 3443–53. http://dx.doi.org/10.3390/md13063443.

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25

Lee, Yu-Sheng, Tsai-Hui Duh, Shu-Sheng Siao, Rey-Chang Chang, Shang-Kwei Wang, and Chang-Yih Duh. "New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides." Marine Drugs 15, no. 12 (2017): 392. http://dx.doi.org/10.3390/md15120392.

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26

Januar, Hedi Indra, Ekowati Chasanah, Cherie A. Motti, Dianne M. Tapiolas, Catherine H. Liptrot, and Anthony D. Wright. "Cytotoxic Cembranes from Indonesian Specimens of the Soft Coral Nephthea sp." Marine Drugs 8, no. 7 (2010): 2142–52. http://dx.doi.org/10.3390/md8072142.

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27

Tsai, Tsung-Chang, Yu-Ting Huang, Shih-Kai Chou, Ming-Cheng Shih, Ching-Ying Chiang, and Jui-Hsin Su. "Cytotoxic Oxygenated Steroids from the Soft Coral Nephthea erecta." Chemical and Pharmaceutical Bulletin 64, no. 10 (2016): 1519–22. http://dx.doi.org/10.1248/cpb.c16-00426.

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28

Rao, M. Rama, K. V. Sridevi, U. Venkatesham, T. Prabhaker Rao, S. S. Lee, and Y. Venkateswarlu. "Four new sesquiterpenoids from the soft coral Nephthea chabrollii." Journal of Chemical Research 2000, no. 5 (2000): 245–47. http://dx.doi.org/10.3184/030823400103167165.

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29

Mehta, G., Y. Venkateswarlu, M. Rama Rao та R. Uma. "A Novel 4α-Methyl Sterol from the Soft Coral Nephthea chabroli". Journal of Chemical Research, № 10 (1999): 628–29. http://dx.doi.org/10.1039/a904057i.

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30

Ma, Ke, Wei Li, Hongwei Fu та ін. "New 4α-methyl steroids from a Chinese soft coral Nephthea sp." Steroids 72, № 14 (2007): 901–7. http://dx.doi.org/10.1016/j.steroids.2007.07.006.

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31

Hegazy, Mohamed-Elamir F., Amira M. Gamal-Eldeen, Tarik A. Mohamed, et al. "New cytotoxic constituents from the Red Sea soft coral Nephthea sp." Natural Product Research 30, no. 11 (2015): 1266–72. http://dx.doi.org/10.1080/14786419.2015.1055266.

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32

Zhang, Weihan, Wing Keung Liu, and Chun-Tao Che. "Polyhydroxylated Steroids and Other Constituents of the Soft Coral Nephthea chabroli." CHEMICAL & PHARMACEUTICAL BULLETIN 51, no. 8 (2003): 1009–11. http://dx.doi.org/10.1248/cpb.51.1009.

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33

Rao, M. Rama, K. V. Sridevi, U. Venkatesham, T. Prabhaker Rao, S. S. Lee, and Y. Venkateswarlu. "ChemInform Abstract: Four New Sesquiterpenoids from the Soft Coral Nephthea chabrollii." ChemInform 31, no. 44 (2000): no. http://dx.doi.org/10.1002/chin.200044197.

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34

Ishii, Takahiro, Reiko Ueoka, Shigeki Matsunaga, and Charles S. Vairappan. "Bioactive secondary metabolites from the Borneon soft corals of the genus Nephthea." Malaysian Journal of Science 29, no. 3 (2010): 262–68. http://dx.doi.org/10.22452/mjs.vol29no3.10.

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35

Duh, Chang-Yih, Shang-Kwei Wang, and Ying-Ling Weng. "Brassicolene, a novel cytotoxic diterpenoid from the Formosan soft coral Nephthea brassica." Tetrahedron Letters 41, no. 9 (2000): 1401–3. http://dx.doi.org/10.1016/s0040-4039(99)02302-3.

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36

Zhang, Jun, Xiao-Jian Liao, Kai-Ling Wang, Zhou Deng, and Shi-Hai Xu. "Cytotoxic cholesta-1,4-dien-3-one derivatives from soft coral Nephthea sp." Steroids 78, no. 4 (2013): 396–400. http://dx.doi.org/10.1016/j.steroids.2012.12.012.

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37

Whuang, Ta-Yuan, Wen-Cheng Tsai, Nan-Fu Chen, et al. "Columnaristerol A, a novel 19-norsterol from the Formosan octocoral Nephthea columnaris." Bioorganic & Medicinal Chemistry Letters 26, no. 20 (2016): 4966–69. http://dx.doi.org/10.1016/j.bmcl.2016.09.007.

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38

Su, JH, BR Peng, SK Chou, MC Shih, and YT Huang. "Steroids and cembranoids from the soft corals Nephthea erecta and Lobophytum crissum." Planta Medica 81, S 01 (2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596635.

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39

Kapojos, Magie Melanie, Remy Emile Petrus Mangindaan, Takahiro Nakazawa, Taiko Oda, Kazuyo Ukai, and Michio Namikoshi. "Three New Nardosinane Type Sesquiterpenes from an Indonesian Soft Coral Nephthea sp." CHEMICAL & PHARMACEUTICAL BULLETIN 56, no. 3 (2008): 332–34. http://dx.doi.org/10.1248/cpb.56.332.

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40

Ishii, Takahiro, Hiroshi Matsuura, Zhan Zhaoqi та Charles Vairappan. "A New 4α-Methylated Sterol from a Nephthea sp. (Nephtheidae) Bornean Soft Coral". Molecules 14, № 9 (2009): 3360–66. http://dx.doi.org/10.3390/molecules14093360.

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41

Patra, Amarendra, and Anadi Majumdar. "Secondary metabolites of a soft coral (Nephthea sp.) of the Bay of Bengal." Arkivoc 2003, no. 9 (2004): 133–39. http://dx.doi.org/10.3998/ark.5550190.0004.916.

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42

Huang, Ya-Ching, Zhi-Hong Wen, Shang-Kwei Wang, Chi-Hsin Hsu, and Chang-Yih Duh. "New anti-inflammatory 4-methylated steroids from the Formosan soft coral Nephthea chabroli." Steroids 73, no. 11 (2008): 1181–86. http://dx.doi.org/10.1016/j.steroids.2008.05.007.

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43

Ray, Anup K., Pran K. Datta, Tapas Das, et al. "Isolation of meso-1,3-Diphenyl-1,3-propanediol from a Soft Coral Nephthea Sp." Journal of Natural Products 54, no. 3 (1991): 854–55. http://dx.doi.org/10.1021/np50075a016.

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44

Mehta, G., Y. Venkateswarlu, M. Rama Rao та R. Uma. "ChemInform Abstract: A Novel 4α-Methyl Sterol from the Soft Coral Nephthea chabroli". ChemInform 31, № 6 (2010): no. http://dx.doi.org/10.1002/chin.200006200.

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45

Allam, Khaled, Amgad Khedr, Ahmed Allam, Mohamed Salaheldin Abdelkader, Ehab Elkhayat, and Mostafa Fouad. "Chemical and Biological Diversity in Nephthea Soft Corals in the Current Decade: A Review." Journal of advanced Biomedical and Pharmaceutical Sciences 4, no. 3 (2021): 124–33. http://dx.doi.org/10.21608/jabps.2021.62966.1121.

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46

Cheng, Shi-Yie, Chang-Feng Dai, and Chang-Yih Duh. "New 4-methylated and 19-oxygenated steroids from the Formosan soft coral Nephthea erecta." Steroids 72, no. 8 (2007): 653–59. http://dx.doi.org/10.1016/j.steroids.2007.05.001.

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47

Cheng, Shi-Yie, Ya-Chiang Huang, Zhi-Hong Wen, et al. "New 19-oxygenated and 4-methylated steroids from the Formosan soft coral Nephthea chabroli." Steroids 74, no. 6 (2009): 543–47. http://dx.doi.org/10.1016/j.steroids.2009.02.004.

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48

Zhang, Wei-Han, Ian D. Williams, and Chun-Tao Che. "Chabrolols A, B and C, three new norditerpenes from the soft coral Nephthea chabroli." Tetrahedron Letters 42, no. 28 (2001): 4681–85. http://dx.doi.org/10.1016/s0040-4039(01)00837-1.

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49

Zhang, Jun, Liang-Chun Li, Kai-Ling Wang, Xiao-Jian Liao, Zhou Deng, and Shi-Hai Xu. "Pentacyclic hemiacetal sterol with antifouling and cytotoxic activities from the soft coral Nephthea sp." Bioorganic & Medicinal Chemistry Letters 23, no. 4 (2013): 1079–82. http://dx.doi.org/10.1016/j.bmcl.2012.12.012.

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50

Duh, Chang-Yih, Shang-Kwei Wang, and Ying-Ling Weng. "ChemInform Abstract: Brassicolene, a Novel Cytotoxic Diterpenoid from the Formosan Soft Coral Nephthea brassica." ChemInform 31, no. 20 (2010): no. http://dx.doi.org/10.1002/chin.200020158.

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