Relevant bibliographies by topics / Neural organoids

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Neural organoids'

Author: Grafiati
Published: 25 May 2024
Last updated: 31 July 2025

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Journal articles on the topic "Neural organoids"

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Werner, Jonathan M., and Jesse Gillis. "Meta-analysis of single-cell RNA sequencing co-expression in human neural organoids reveals their high variability in recapitulating primary tissue." PLOS Biology 22, no. 12 (2024): e3002912. https://doi.org/10.1371/journal.pbio.3002912.

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Human neural organoids offer an exciting opportunity for studying inaccessible human-specific brain development; however, it remains unclear how precisely organoids recapitulate fetal/primary tissue biology. We characterize field-wide replicability and biological fidelity through a meta-analysis of single-cell RNA-sequencing data for first and second trimester human primary brain (2.95 million cells, 51 data sets) and neural organoids (1.59 million cells, 173 data sets). We quantify the degree primary tissue cell type marker expression and co-expression are recapitulated in organoids across 10
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Zhao, Yihan. "Progress in the construction and application of neural organoids." Highlights in Science, Engineering and Technology 99 (June 18, 2024): 262–68. http://dx.doi.org/10.54097/6x851787.

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With the establishment of three-dimensional (3D) cell culture methods, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), or tissue-resident stem cells/progenitor cells can be cultured in vitro to produce structures similar to organs, called "organoids".Compared with the traditional model, neural organoids have unique advantages, such as being able to perform high-throughput drug screening, organ development simulation in vitro, and predict the individual response to drugs more accurately. Therefore, combining the advantages of organoid models with traditional models will ope
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Yu, Xiyao, Xiaoting Meng, Zhe Pei, et al. "Physiological Electric Field: A Potential Construction Regulator of Human Brain Organoids." International Journal of Molecular Sciences 23, no. 7 (2022): 3877. http://dx.doi.org/10.3390/ijms23073877.

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Brain organoids can reproduce the regional three-dimensional (3D) tissue structure of human brains, following the in vivo developmental trajectory at the cellular level; therefore, they are considered to present one of the best brain simulation model systems. By briefly summarizing the latest research concerning brain organoid construction methods, the basic principles, and challenges, this review intends to identify the potential role of the physiological electric field (EF) in the construction of brain organoids because of its important regulatory function in neurogenesis. EFs could initiate
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Pflug, Florian G., Simon Haendeler, Christopher Esk, Dominik Lindenhofer, Jürgen A. Knoblich, and Arndt von Haeseler. "Neutral competition explains the clonal composition of neural organoids." PLOS Computational Biology 20, no. 4 (2024): e1012054. http://dx.doi.org/10.1371/journal.pcbi.1012054.

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Neural organoids model the development of the human brain and are an indispensable tool for studying neurodevelopment. Whole-organoid lineage tracing has revealed the number of progenies arising from each initial stem cell to be highly diverse, with lineage sizes ranging from one to more than 20,000 cells. This high variability exceeds what can be explained by existing stochastic models of corticogenesis and indicates the existence of an additional source of stochasticity. To explain this variability, we introduce the SAN model which distinguishes Symmetrically diving, Asymmetrically dividing,
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Logan, Sarah, Thiago Arzua, Yasheng Yan, et al. "Dynamic Characterization of Structural, Molecular, and Electrophysiological Phenotypes of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids, and Comparison with Fetal and Adult Gene Profiles." Cells 9, no. 5 (2020): 1301. http://dx.doi.org/10.3390/cells9051301.

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Background: The development of 3D cerebral organoid technology using human-induced pluripotent stem cells (iPSCs) provides a promising platform to study how brain diseases are appropriately modeled and treated. So far, understanding of the characteristics of organoids is still in its infancy. The current study profiled, for the first time, the electrophysiological properties of organoids at molecular and cellular levels and dissected the potential age equivalency of 2-month-old organoids to human ones by a comparison of gene expression profiles among cerebral organoids, human fetal and adult b
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Lebakken, Connie S., William Richards, Sophia Clark, et al. "Abstract 3991: A neural organoid glioblastoma model to assess tumor microenvironment interactions and tumor associated microglia and macrophage responses." Cancer Research 85, no. 8_Supplement_1 (2025): 3991. https://doi.org/10.1158/1538-7445.am2025-3991.

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Abstract Glioblastoma (GBM) is a treatment resistant brain tumor with a median survival post-diagnosis of only 18-20 months. One significant limitation in the development of effective therapeutics for GBM is the lack of suitable pre-clinical models that accurately replicate human GBM and the surrounding tumor microenvironment (TME) cell interactions. Tumor Associated Microglia and Myeloid-derived Macrophages, collectively TAMs, are of particular interest due to their essential role in tumor immunosuppression. We have adapted Stem Pharm’s neural organoid technology by incorporating GBM cell lin
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Kim, Soo-hyun, and Mi-Yoon Chang. "Application of Human Brain Organoids—Opportunities and Challenges in Modeling Human Brain Development and Neurodevelopmental Diseases." International Journal of Molecular Sciences 24, no. 15 (2023): 12528. http://dx.doi.org/10.3390/ijms241512528.

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Brain organoids are three-dimensional (3D) structures derived from human pluripotent stem cells (hPSCs) that reflect early brain organization. These organoids contain different cell types, including neurons and glia, similar to those found in the human brain. Human brain organoids provide unique opportunities to model features of human brain development that are not well-reflected in animal models. Compared with traditional cell cultures and animal models, brain organoids offer a more accurate representation of human brain development and function, rendering them suitable models for neurodevel
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Birch, Jonathan. "When is a brain organoid a sentience candidate?" Molecular Psychology: Brain, Behavior, and Society 2 (October 18, 2023): 22. http://dx.doi.org/10.12688/molpsychol.17524.1.

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It would be unwise to dismiss the possibility of human brain organoids developing sentience. However, scepticism about this idea is appropriate when considering current organoids. It is a point of consensus that a brainstem-dead human is not sentient, and current organoids lack a functioning brainstem. There are nonetheless troubling early warning signs, suggesting organoid research may create forms of sentience in the near future. To err on the side of caution, researchers with very different views about the neural basis of sentience should unite behind the “brainstem rule”: if a neural organ
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Mensah-Brown, Kobina G., James Lim, Dennis Jgamadze, et al. "96101 Temporal Evolution of Neural Activity in Human Brain Organoids." Journal of Clinical and Translational Science 5, s1 (2021): 23. http://dx.doi.org/10.1017/cts.2021.464.

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ABSTRACT IMPACT: This study will provide the essential characterization of intrinsic neural activity in human brain organoids, both at the single cell and network levels, to harness for translational purposes. OBJECTIVES/GOALS: Brain organoids are 3D, stem cell-derived neural tissues that recapitulate neurodevelopment. However, to levy their full translational potential, a deeper understanding of their intrinsic neural activity is essential. Here, we present our preliminary analysis of maturing neural activity in human forebrain organoids. METHODS/STUDY POPULATION: Forebrain organoids were gen
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Branciforti, Francesco, Massimo Salvi, Filippo D’Agostino, et al. "Segmentation and Multi-Timepoint Tracking of 3D Cancer Organoids from Optical Coherence Tomography Images Using Deep Neural Networks." Diagnostics 14, no. 12 (2024): 1217. http://dx.doi.org/10.3390/diagnostics14121217.

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Recent years have ushered in a transformative era in in vitro modeling with the advent of organoids, three-dimensional structures derived from stem cells or patient tumor cells. Still, fully harnessing the potential of organoids requires advanced imaging technologies and analytical tools to quantitatively monitor organoid growth. Optical coherence tomography (OCT) is a promising imaging modality for organoid analysis due to its high-resolution, label-free, non-destructive, and real-time 3D imaging capabilities, but accurately identifying and quantifying organoids in OCT images remain challengi
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Dissertations / Theses on the topic "Neural organoids"

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Omer, Attya. "Modeling human neural development and diseases using pluripotent stem cells." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS589.

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La microcéphalie est une maladie neurologique du nouveau-né qui se traduit par une circonférence réduite de la tête, une déficience intellectuelle et des défauts anatomiques du cerveau. La microcéphalie peut être la conséquence d’une infection, de stress environnementaux ou de mutations génétiques.Le cerveau commence à se former dès la cinquième semaine de grossesse et est majoritairement constitué de cellules souches neuronales, cellules qui conservent une capacité a se reproduire a l’identique sans se spécialiser. Cette première phase de prolifération est importante pour générer suffisamment
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Workman, Michael J. "Generating 3D human intestinal organoids with an enteric nervous system." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1416570664.

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Koshy, Aysis. "Characterization of Neural Development : Linking Retinoic Acid Receptors to Cell Fate and Modelling Tumorigenesis in Brain Organoids." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL119.

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Le développement du système nerveux central dans l'embryon dépend d'une signalisation opportune et précise des molécules. L'acide rétinoïque est l'une de ces molécules bien caractérisées par son impact sur le développement du cerveau et des yeux. Sous sa forme métaboliquement active, l'ATRA (acide All Trans Retinoïque) se lie aux récepteurs de l'acide rétinoïque (RAR) et contrôle l'expression d'une panoplie de gènes participant à des évènements impliqués dans la maturation cellulaire ainsi qu'à l'apoptose. Le RAR existe sous trois isotypes - RARα, RARβ et RARγ. Au cours du développement embryo
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Saha, Sulov. "Rôle du métabolisme one-carbone dans le développement du néocortex." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSES010.

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Le néocortex des mammifères est unique en raison d'innovations évolutives telles que l'augmentation de sa taille et l'apparition de capacités cognitives complexes. Ces attributs nécessitent la mise en place de circuits neuronaux qui s'appuient sur une production stéréotypée de neurones et de cellules gliales à partir de progéniteurs neuraux (NPC). Des études pionnières ont montré que des programmes intrinsèques et des facteurs extrinsèques régulent le devenir des NPC pour équilibrer leur prolifération et leur différentiation en sous types cellulaires distincts. Le métabolisme cellulaire intègr
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Klaus, Johannes [Verfasser], and Magdalena [Akademischer Betreuer] Götz. "Modeling neuronal heterotopias using iPSC derived neural stem cells, neurons and cerebral organoids derived from patients with mutations in FAT4 and DCHS1 / Johannes Klaus ; Betreuer: Magdalena Götz." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1148275789/34.

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Prudon, Nicolas. "Integrative study, from the cell to the animal model, of the development of a cell therapy for Parkinson's disease." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0071.

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Un ensemble d'études précliniques soutient désormais le développement de thérapies de remplacement cellulaire dérivées de cellules souches pluripotentes pour soulager les symptômes moteurs chez les patients parkinsoniens. Le remplacement de la principale population cellulaire dysfonctionnelle au sein de la maladie, les neurones dopaminergiques A9, est l'objectif principal de ces thérapies. Pour y parvenir, la plupart des approches thérapeutiques impliquent la greffe de suspensions cellulaires de progéniteurs dopaminergiques. Cependant, une quantité considérable de cellules meurent pendant le p
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Wimmer, Ryszard. "Migration of neural stem cells during human neocortical development." Electronic Thesis or Diss., Université Paris sciences et lettres, 2024. http://www.theses.fr/2024UPSLS016.

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Chez les espèces gyrencéphaliques, et en particulier chez l'homme, la forte augmentation de la taille du néocortex est largement soutenue par une niche neurogénique élargie, la zone sous-ventriculaire externe (oSVZ). Cela est dû en grande partie à l'amplification d'une population de cellules souches neurales, les cellules gliales radiales basales (bRG, également appelées oRG). Les cellules bRG colonisent la zone sous-ventriculaire externe grâce à un mouvement dépendant de l'acto-myosine appelé translocation somale mitotique (MST). Le mécanisme moléculaire exact de la MST, la question de savoir
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Frank, Elie. "Modélisation du Syndrome d'Alström à partir de cellules souches pluripotentes humaines pour l'identification de cibles moléculaires d'intérêt thérapeutique." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASQ041.

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Le syndrome d'Alström (SA) est une maladie monogénique récessive multi-systémique, caractérisée notamment par une perte de l'audition et de la vue, une obésité, un diabète de type 2, une cardiomyopathie et une insuffisance hépatique et rénale progressive. Les symptômes affectant la vision se développent dès les premières semaines après la naissance et mènent progressivement à une perte totale de la vue. À l'heure actuelle, aucun traitement ne permet de soigner cette maladie et seules des solutions permettant de réduire les effets des symptômes peuvent être proposées.L'objet de la thèse est de
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FARIA, PEREIRA MARLENE CRISTINA. "EPIGENETIC AND FUNCTIONAL ASSESSMENT OF ENHANCEROPATHIES ACROSS HUMAN MODELS: FOCUS ON GABRIELE-DE VRIES SYNDROME." Doctoral thesis, Università degli Studi di Milano, 2022. https://hdl.handle.net/2434/945230.

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Yin Yang 1 (YY1) is a ubiquitous zinc finger transcription factor (TF) that occupies active enhancers and promoters contributing to physical interactions between these regions via DNA looping. Increasing evidence shows that disruption of non-coding regions such as enhancers is prevalent across different neurodevelopmental disorders (NDDs) with intellectual disability (ID) features. Indeed, YY1 haploinsufficiency causes a NDD with ID, named Gabriele-de Vries syndrome (GADEVS). Although it is known that YY1 controls the expression of a dazzling list of genes and influences various cellular proce
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Baillie-Johnson, Peter. "The generation of a candidate axial precursor in three dimensional aggregates of mouse embryonic stem cells." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/267818.

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Textbook accounts of vertebrate embryonic development have been based largely upon experiments on amphibian embryos, which have shown that the tissues of the trunk and tail are organised from distinct precursors that existed during gastrulation. In the mouse and chick, however, retrospective clonal analyses and transplantation experiments have demonstrated that the amniote body instead arises progressively from a population of axial precursors that are common to both the neural and mesodermal tissues of the trunk and tail. For this reason, they are known as neuro-mesodermal progenitors (NMps).
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Books on the topic "Neural organoids"

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The Emerging Field of Human Neural Organoids, Transplants, and Chimeras. National Academies Press, 2021. http://dx.doi.org/10.17226/26078.

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National Academies of Sciences, Engineering, and Medicine. Emerging Field of Human Neural Organoids, Transplants, and Chimeras: Science, Ethics, and Governance. National Academies Press, 2021.

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Affairs, Policy and Global, Technology, and Law Committee on Science, National Academies of Sciences, Engineering, and Medicine, and Committee on Ethical, Legal, and Regulatory Issues Associated with Neural Chimeras and Organoids. Emerging Field of Human Neural Organoids, Transplants, and Chimeras: Science, Ethics, and Governance. National Academies Press, 2021.

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Affairs, Policy and Global, Technology, and Law Committee on Science, National Academies of Sciences, Engineering, and Medicine, and Committee on Ethical, Legal, and Regulatory Issues Associated with Neural Chimeras and Organoids. The Emerging Field of Human Neural Organoids, Transplants, and Chimeras: Science, Ethics, and Governance. National Academies Press, 2022.

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Book chapters on the topic "Neural organoids"

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Sakaguchi, Hideya, and Nozomu Takata. "Stem Cell-Derived Neural Organoids: From the Origin to Next Generation." In Handbook of Stem Cell Applications. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0846-2_6-1.

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Sakaguchi, Hideya, and Nozomu Takata. "Stem Cell-Derived Neural Organoids: From the Origin to Next Generation." In Handbook of Stem Cell Applications. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-7119-0_6.

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Sebastian, Rebecca, Narciso S. Pavon, Yoonjae Song, Karmen T. Diep, and ChangHui Pak. "Method to Generate Dorsal Forebrain Brain Organoids from Human Pluripotent Stem Cells." In Stem Cell-Based Neural Model Systems for Brain Disorders. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3287-1_13.

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Murray, Liam, Meagan N. Olson, Nathaniel Barton, Pepper Dawes, Yingleong Chan, and Elaine T. Lim. "FACS-Based Sequencing Approach to Evaluate Cell Type to Genotype Associations Using Cerebral Organoids." In Stem Cell-Based Neural Model Systems for Brain Disorders. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3287-1_15.

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Li, Kangle, Longjun Gu, Hongwei Cai, and Feng Guo. "Organoid Computing: Leveraging Organoid Neural Networks for Artificial Intelligence." In Collaborative Bioethics. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-72371-1_12.

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Takahashi, Toshio. "New Trends and Perspectives in the Function of Non-neuronal Acetylcholine in Crypt–Villus Organoids in Mice." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/7651_2016_1.

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Birch, Jonathan. "Neural Organoids." In The Edge of Sentience. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/9780191966729.003.0012.

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Abstract Human neural organoids are showing great promise as models of the human brain. It would be hasty to dismiss the possibility they could develop sentience. However, scepticism about this idea is appropriate when considering current organoids (at the time of writing). This is not because of their size, but because of their organization: current organoids lack a functioning brainstem or anything equivalent to one. There are nonetheless troubling early warning signs suggesting that organoid research may create forms of sentient being in the future. Researchers with very different views abo
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Gong, Jing, Jiahui Kang, Minghui Li, Xiao Liu, Jun Yang, and Haiwei Xu. "Applications of Neural Organoids in Neurodevelopment and Regenerative Medicine." In Organoids [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104044.

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Recent advances in stem cell technologies have enabled the application of three-dimensional neural organoids for exploring the mechanisms of neurodevelopment and regenerative medicine. Over the past decade, series of studies have been carried out to investigate the cellular and molecular events of human neurogenesis using animal models, while the species differences between animal models and human being prevent a full understanding of human neurogenesis. Human neural organoids provide a new model system for gaining a more complete understanding of human neural development and their application
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Subramanian, Arunkumar, Sabesh S, Naraien Karthikeyan S, and T. Tamilanban. "NEURAL ORGANOIDS: A NEW FRONTIER IN NEURODEGENERATIVE DISEASE MODELLING AND DRUG SCREENING." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 6. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn6p1ch6.

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Neurodegenerative diseases (NDDs) are a group of disorders characterized by nerve cell degeneration, including Alzheimer's, Parkinson's, and Huntington's diseases. Current research relies on animal models and 2D cell cultures, limiting accurate disease replication. However, 3D neural organoids, derived from stem cells, offer exciting prospects for NDD study. Neural organoids closely resemble the developing human brain and have become valuable tools for disease modeling and drug screening. They can differentiate into specific neural cell types and mimic disease-specific protein aggregation. Bra
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Varela, Maria C., Ranmal Samarasinghe, and Jack M. Parent. "Functional Exploration of Epilepsy Genes in Patient-Derived Cells." In Jasper's Basic Mechanisms of the Epilepsies, 5th ed., edited by Jeffrey L. Noebels. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197549469.003.0042.

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Abstract Advances in human induced pluripotent stem cell (iPSC) approaches have greatly expanded the use of patient-derived cellular models, including cortical-like neurons and brain organoids, to study genetic epilepsies. New protocols to differentiate iPSCs into various neural cell types, and to generate brain region-specific organoids, have accelerated progress. In addition, the application of gene editing techniques adds rigor to these studies and offers the opportunity to model rare genetic epilepsies by enabling correction or insertion of mutations to generate isogenic controls or virtua
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Conference papers on the topic "Neural organoids"

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Shettigar, Nandan, Lamees El Nihum, Ashok Thyagarajan, Debjyoti Banerjee, and Robert Krencik. "Design, Microfabrication and Testing of Brain-on-a-Chip (BOC) Platform Using Neural Organoids (Spheroids)." In ASME 2021 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/fedsm2021-65894.

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Abstract Three-dimensional (3D) organoid engineering aims to steer cell aggregates toward physiological mimicking of human tissue and organ systems at the cellular level, essentially serving as tissue and organ proxies that recapitulate biological parameters (e.g., spatial organization of heterogenous tissue-specific cells, cell-cell interactions, etc.). Currently, attempts at generation of brain organoids do not mature beyond the prenatal brain equivalent, the major obstacle being the lack of vascularization in the initial embryoid bodies that ultimately limit the growth and maturation of the
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Shettigar, Nandan, C. Steve Suh, and Debjyoti Banerjee. "On Developing a Novel Brain-On-Chip Platform for Enhanced Control and Design of 3D Neural Circuit Informational Dynamics." In ASME 2024 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2024. https://doi.org/10.1115/imece2024-147442.

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Abstract Characterizing, monitoring, and controlling neural dynamics remains an elusive goal for research efforts ranging from neuroscience to computer science. The approaches attempt to unearth a richer interpretation for the nonlinear, time-varying hierarchy of biological hardware organizations. Some promising advances with specific investigations focusing on classes of problems pertaining to how emergent neural network dynamics produces 1) distinct cognitive states including degenerative pathologies and 2) reproducing, maintaining and controlling efficient information processing capabilitie
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Wilson, Madison, Martin Thunemann, Francesca Puppo, et al. "Transparent neural interface for in vivo interrogation of human organoids." In Neural Imaging and Sensing 2021, edited by Qingming Luo, Jun Ding, and Ling Fu. SPIE, 2021. http://dx.doi.org/10.1117/12.2579350.

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MacDonald, Michael, Randy Fennel, Asha Singanamalli, et al. "Improved automated segmentation of human kidney organoids using deep convolutional neural networks." In Image Processing, edited by Bennett A. Landman and Ivana Išgum. SPIE, 2020. http://dx.doi.org/10.1117/12.2549830.

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Wilson, Madison N., Martin Thunemann, Francesca Puppo, et al. "Investigation of functional integration of cortical organoids transplanted in vivo towards future neural prosthetics applications." In 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2023. http://dx.doi.org/10.1109/ner52421.2023.10123847.

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Zhang, Jinqiu, Jolene Ooi, Sarah R. Langley, et al. "A48 Expanded HTT cag repeats disrupt the balance between neural progenitor expansion and differentiation in isogenic human cerebral organoids." In EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/jnnp-2018-ehdn.46.

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Pitta, Marina Galdino da Rocha, Jordy Silva de Carvalho, Luzilene Pereira de Lima, and Ivan da Rocha Pitta. "iPSC therapies applied to rehabilitation in parkinson’s disease." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.022.

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Background: Parkinson’s disease (PD) is a neurological disorder that affects movement, mainly due to damage and degeneration of the nigrostriatal dopaminergic pathway. The diagnosis is made through a clinical neurological analysis where motor characteristics are considered. There is still no cure, and treatment strategies are focused on symptoms control. Cell replacement therapies emerge as an alternative. Objective: This review focused on current techniques of induced pluripotent stem cells (iPSCs). Methods: The search terms used were: “Parkinson’s Disease”, “Stem cells” and “iPSC”. Open arti
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El Nihum, Lamees, Nandan Shettigar, Debjyoti Banerjee, and Robert Krencik. "A Comprehensive Review of Three-Dimensional Neuro-Organoids and Engineering Brain-on-a-Chip Microfluidic Devices." In ASME 2021 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/fedsm2021-65892.

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Abstract The focus of this review is to describe advances in three-dimensional (3D) organoids reported in the literature with an emphasis on the engineering of microfluidic device platforms for investigating neuro-organoids. Furthermore, the paper will assess current limitations in microfluidic design that must be addressed for realizing the full potential of brain-on-a-chip devices.
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Bahr, AS, M. Simon, D. Capper, et al. "Modeling low-grade glioma with cerebral organoids." In 28th Annual Meeting of the working group “Experimental Neuro-Oncology”. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1696327.

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Ma, Yuanzheng, Davit Khutsishvili, Zitian Wang, Xun Guan, and Shaohua Ma. "Exploring the Neural Organoid in High Definition: Physics-Inspired High-Throughout Super-Resolution 3D Image Reconstruction." In 2023 Asia Communications and Photonics Conference/2023 International Photonics and Optoelectronics Meetings (ACP/POEM). IEEE, 2023. http://dx.doi.org/10.1109/acp/poem59049.2023.10368794.

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Reports on the topic "Neural organoids"

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Yeh, Ashley, Britney Pennington, Mohamed Faynus, Mika Katsura, and Dennis Clegg. Determining Essential Factors Required for Expediting Neural Induction of Precursors to Retinal Organoids. Journal of Young Investigators, 2025. https://doi.org/10.22186/jyi.28.1.1.1.

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