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Dissertations / Theses on the topic 'Neuron'

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1

Moonens, Sofie. "Mirror Neurons : The human mirror neuron system." Thesis, Högskolan i Skövde, Institutionen för kommunikation och information, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-6103.

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This literature review explores human mirror neurons from several angles. First it retells mirror neuron history, from the initial discovery in the macaque monkey research through to the experiments determining if there is a human brain homologue. Then the merits of two opposing evolutionary views – mirror neurons as an adaptation or an association, here referring to an adaptation’s byproduct – are discussed. Lastly the autistic mirror neuron dysfunction hypothesis – stating that a faulty mirror neuron system is at the basis of autistic behavioral patterns – is examined for its validity but ul
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Steinbush, H. W. M. "Het neuron als bruggenbouwer "bridging disciplines by neurons" /." Maastricht : Maastricht : Instituut hersenen en gedrag ; University Library, Universiteit Maastricht [host], 1999. http://arno.unimaas.nl/show.cgi?fid=12984.

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3

Viñoles, Serra Mireia. "Dynamics of Two Neuron Cellular Neural Networks." Doctoral thesis, Universitat Ramon Llull, 2011. http://hdl.handle.net/10803/9154.

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Les xarxes neuronals cel·lulars altrament anomenades CNNs, són un tipus de sistema dinàmic que relaciona diferents elements que s'anomenen neurones via unes plantilles de paràmetres. Aquest sistema queda completament determinat coneixent quines són les entrades a la xarxa, les sortides i els paràmetres o pesos. En aquest treball fem un estudi exhaustiu sobre aquest tipus de xarxa en el cas més senzill on només hi intervenen dues neurones. Tot i la simplicitat del sistema, veurem que pot tenir una dinàmica molt rica. <br/><br/>Primer de tot, revisem l'estabilitat d'aquest sistema des de dos pun
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Xu, Shuxiang, University of Western Sydney, and of Informatics Science and Technology Faculty. "Neuron-adaptive neural network models and applications." THESIS_FIST_XXX_Xu_S.xml, 1999. http://handle.uws.edu.au:8081/1959.7/275.

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Artificial Neural Networks have been widely probed by worldwide researchers to cope with the problems such as function approximation and data simulation. This thesis deals with Feed-forward Neural Networks (FNN's) with a new neuron activation function called Neuron-adaptive Activation Function (NAF), and Feed-forward Higher Order Neural Networks (HONN's) with this new neuron activation function. We have designed a new neural network model, the Neuron-Adaptive Neural Network (NANN), and mathematically proved that one NANN can approximate any piecewise continuous function to any desired accuracy
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Xu, Shuxiang. "Neuron-adaptive neural network models and applications." Thesis, [Campbelltown, N.S.W. : The Author], 1999. http://handle.uws.edu.au:8081/1959.7/275.

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Artificial Neural Networks have been widely probed by worldwide researchers to cope with the problems such as function approximation and data simulation. This thesis deals with Feed-forward Neural Networks (FNN's) with a new neuron activation function called Neuron-adaptive Activation Function (NAF), and Feed-forward Higher Order Neural Networks (HONN's) with this new neuron activation function. We have designed a new neural network model, the Neuron-Adaptive Neural Network (NANN), and mathematically proved that one NANN can approximate any piecewise continuous function to any desired accuracy
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Xu, Shuxiang. "Neuron-adaptive neural network models and applications /." [Campbelltown, N.S.W. : The Author], 1999. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030702.085320/index.html.

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7

Boatin, William. "Characterization of neuron models." Thesis, Available online, Georgia Institute of Technology, 2005, 2005. http://etd.gatech.edu/theses/available/etd-04182005-181732/.

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Thesis (M. S.)--Electrical and Computer Engineering, Georgia Institute of Technology, 2006.<br>Dr. Robert H. Lee, Committee Member ; Dr. Kurt Wiesenfeld, Committee Member ; Dr Robert J. Butera, Committee Member.
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8

Stoller, Jonathan (Jonathan M. ). "Online neuron reconstruction." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106377.

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Thesis: M. Eng. in Computer Science and Engineering, Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (page 47).<br>In this thesis, I designed an algorithm that traces neurons through the images of various datasets extracted from mouse brains. The algorithm is implemented in Python and relies on
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9

Regehr, Wade G. Pine Jerry Rutledge David B. "Neuron-microdevice connections /." Diss., Pasadena, Calif. : California Institute of Technology, 1988. http://resolver.caltech.edu/CaltechETD:etd-11092007-084226.

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10

Benda, Jan. "Single neuron dynamics." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2002. http://dx.doi.org/10.18452/14684.

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Das Neuron ist das zentrale Element in der Informationsverarbeitung im Nervensystem. In dieser Arbeit werden verschiedene Aspekte der Spikegenerierung sowohl theoretisch als auch experimentell untersucht. Phasen-Rotatoren verschiedener Komplexität werden zur Vorhersage von Spikezeitpunkten vorgestellt. Die Kennlinie eines Neurons wird dabei als wichtiger Parameter für diese Modelle verwendet, damit diese leicht auf echte Neurone anwendbar sind. Die Phasenantwortkurve als ein zweiter wichtiger Aspekt der Spikedynamik wird zur Erweiterung der Modelle verwendet. Solange ein Neuron in seinem über
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11

Donachy, Shaun. "Spiking Neural Networks: Neuron Models, Plasticity, and Graph Applications." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3984.

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Networks of spiking neurons can be used not only for brain modeling but also to solve graph problems. With the use of a computationally efficient Izhikevich neuron model combined with plasticity rules, the networks possess self-organizing characteristics. Two different time-based synaptic plasticity rules are used to adjust weights among nodes in a graph resulting in solutions to graph prob- lems such as finding the shortest path and clustering.
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12

Martin, Joanne Elizabeth. "Cellular pathology of the lower motor neuron in motor neuron disease." Thesis, Queen Mary, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266426.

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13

Domert, Jakob. "Neuron-to-neuron propagation of neurodegenerative proteins; relation to degradative systems." Doctoral thesis, Linköpings universitet, Avdelningen för neuro- och inflammationsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-134667.

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Alzheimer’s disease (AD) and Parkinson’s disease (PD) are defined by neurodegeneration and accumulations of misfolded proteins that spread through the brain in a well characterized manner. In AD these accumulations consist mainly of β-amyloid (Aβ) and tau, while in PD, α-synuclein (α-syn) make up the characteristic lewy pathology.     The general aim of this thesis was to investigate mechanisms associated with neurotoxic peptide activity by Aβ, tau and α-syn in relation to cellular degradation and transfer with a cell-to-cell transfer model system.    We found that intercellular transfer of ol
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14

Tuffy, Fergal. "Inter-neuron interconnect strategies for hardware implementations of neural networks." Thesis, University of Ulster, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441169.

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15

Podéus, Henrik. "Neural response of a Neuron population : A mathematical modelling approach." Thesis, Linköpings universitet, Avdelningen för medicinsk teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-177797.

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The brain – the organ that allows us to be aware of our surroundings – consists of a complex network of neurons, which seemingly allows the human brain to be able of abstract thinking, emotions, and cognitive function. To learn how the brain is capable of this, the two main branches of neuroscience study either neurons in detail, or how they communicate within neuronal networks. Both these branches often tackle the complexity using a combination of experiments and mathematical modelling. A third and less studied aspect of neuroscience concerns the neurovascular coupling (NVC), for which my res
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PAULA, NETO Fernando Maciano de. "Quantum weightless neuron dynamics." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/17362.

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Submitted by Isaac Francisco de Souza Dias (isaac.souzadias@ufpe.br) on 2016-07-13T19:29:03Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) final.pdf: 6504039 bytes, checksum: 6f7f7f9e2f6435f17fbf9659accd6d63 (MD5)<br>Made available in DSpace on 2016-07-13T19:29:03Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) final.pdf: 6504039 bytes, checksum: 6f7f7f9e2f6435f17fbf9659accd6d63 (MD5) Previous issue date: 2016-03-01<br>CNPQ<br>A wide spectrum of social, biological, physical, chemical
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Mekemeza, Ona Keshia. "Photonic spiking neuron network." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2023. http://www.theses.fr/2023UBFCD052.

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Les réseaux neuromorphiques pour le traitement d'informations ont pris une placeimportante aujourd'hui notamment du fait de la montée en complexité des tâches à effectuer : reconnaissance vocale, corrélation d'images dynamiques, prise de décision rapide multidimensionnelle, fusion de données, optimisation comportementale, etc... Il existe plusieurs types de tels réseaux et parmi ceux- ci les réseaux impulsionnels, c'est-à-dire, ceux dont le fonctionnement est calqué sur celui des neurones corticaux. Ce sont ceux qui devraient offrir le meilleur rendement énergétique donc le meilleur passage à
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18

Fame, Ryan Marie. "Molecular Controls over Developmental Acquisition of Diverse Callosal Projection Neuron Subtype Identities." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10591.

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The mammalian neocortex is an exquisite, highly organized brain structure composed of hundreds of subpopulations of neurons and glia, precisely connected to enable motor control, sensory perception, information integration, and planning. Unique molecular, structural, and anatomical neuronal properties underlie diverse functionality, endowing much of the neocortex’s complex processing power. Neocortical size correlates with information processing capacity, suggesting that increased neuronal number and diversity begets increased sophistication. One excitatory projection neuron type, callosal pro
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19

Agholme, Lotta. "The involvement of degradation pathways and neuron-to-neuron transmission in Alzheimer’s disease." Doctoral thesis, Linköpings universitet, Geriatrik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-81341.

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Although the vast majority of Alzheimer’s disease (AD) cases are of the sporadic type, mutations causing the familial form have been the focus of AD research for decades. The disease is pathologically characterised by β-amyloid (Aβ) and tau protein aggregates in neuritic plaques and neurofibrillary tangles. Furthermore, it is known that AD pathology spreads throughout the brain, most often along the same anatomical pattern. However, so far no cause for the sporadic form of the disease has been found. Accumulation of protein aggregates as well as decreased activity of the protein degradation sy
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20

Sargsyan, Siranush Anna. "Microglial activationas a potential contributor to motor neuron injury in motor neuron disease." Thesis, University of Sheffield, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444237.

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21

Enjin, Anders. "Neural Control of Movement : Motor Neuron Subtypes, Proprioception and Recurrent Inhibition." Doctoral thesis, Uppsala universitet, Genetisk utvecklingsbiologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-147361.

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Movement is central for life, and all animals depend on accurate regulation of movement for purposeful behavior. There is great diversity of movements, ranging between simple and vital breathing movements to minute and subtle movements of the face used to communicate emotions. Consequently, motor neurons, which are the only route of central nervous system output, are essential for all motor behaviors. To control the many motor behaviors expressed by an animal, motor neurons are exposed to a large number and variety of modulating synaptic inputs and have evolved into subtypes with specific func
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22

Filho, Edson Costa de Barros Carvalho. "Investigation of Boolean neural networks on a novel goal-seeking neuron." Thesis, University of Kent, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277285.

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23

Roy, Nipa. "Neural Field Theory of Nonlinear Wave-Wave and Wave-Neuron Processes." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18791.

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Biophysical processes related to the modulation of cellular mechanisms occur due to either presynaptic or postsynaptic effects. These processes involve some physiological phenomena whose different dynamics can potentially be distinguished via traces they leave in the power spectra of brain activity and/or connectivity fluctuations. Systematic expansion of NFT equations in terms of nonlinear response functions is formulated in Chapter 2 to enable a wide variety of nonlinear wave-wave and wave-neuron processes. This theory helps to handle neural quantities such as firing rates, neural field, som
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24

Hanson, Linda. "Neuron och den demokratiska styrkedjan." Thesis, Swedish National Defence College, Swedish National Defence College, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:fhs:diva-743.

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<p>On the 13th of June 2005 the Minister of Defence, Leni Björklund, was subjected to a formal complaint addressed to the Committee on the Constitution concerning her handling of a specific co-operation project with France. The project concerned the development of a technology demonstrator for an UCAV called Neuron. The reason for the complaint was that the Minister of Defence had failed to present the project to the parliament and thus bypassed a parliamentary decision. Such negligence might be considered unlawful under the Swedish Constitution. The issue became public during an unscheduled m
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25

Stringer, Charles Edward Alexander. "Calcium dependent astrocyte-neuron communication." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/32690.

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The discovery of direct communication between astrocytes and neurons has changed the perception of astrocytes from passive support cells to active partners in information processing. Astrocytes express myriad neurotransmitter receptors and have been shown to release neurotransmitters, allowing these cells to respond and signal to adjacent neurons, respectively. Astrocytes can rapidly respond to neurotransmitters with a rise in [Ca²⁺]i and astrocyte neurotransmitter release has been shown to be calcium dependent. The purpose of this research was to investigate unknown aspects of astrocyte
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26

Farquhar, Ethan David. "A biologically inspired silicon neuron." Thesis, Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/14792.

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27

PEDROZA, LUIZ CARLOS C. "EXTENSION OPERATOR AND NEURON NETWORK." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 1997. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=8452@1.

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COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>Na tese se desenvolve a teoria do Operador de extensão (OPEX) e utiliza-se desta para compreender melhor algumas questões relativas a teoria de Redes Neurais(RN). A abordagem de Redes Neurais pela ótica do Operador de Extensão possibilita também um melhoramento no algoritmo de retropropagação de erro usado no treinamento supervisionado das Redes Neurais.<br>In this thesis, theory of Extension Operator is developed and used to understand some questions related to Neuron Networks Theory. The approach of Neuron Networs throug
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28

Goetz, Lea. "Single neuron computation in vivo." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10062620/.

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Single neurons form the fundamental information processing units of the brain. Yet despite our growing knowledge of the electrophysiological and molecular properties of single neurons and their dendrites, little is known about their contribution to information processing in vivo, which depends strongly on the patterns of synaptic input and the way in which they engage active dendritic mechanisms. Here, I address the input-output function of single neurons in vivo and the role played by active dendrites in pyramidal neurons of mouse primary visual cortex using a dual modelling and experimental
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Harkin, Emerson. "A Simplified Serotonin Neuron Model." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38533.

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30

Shepardson, Dylan. "Algorithms for inverting Hodgkin-Huxley type neuron models." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/31686.

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Thesis (Ph.D)--Algorithms, Combinatorics, and Optimization, Georgia Institute of Technology, 2010.<br>Committee Chair: Tovey, Craig; Committee Member: Butera, Rob; Committee Member: Nemirovski, Arkadi; Committee Member: Prinz, Astrid; Committee Member: Sokol, Joel. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Marquilly, Claire. "Rôle de la protéine APPL dans la croissance axonale des corps pédonculés chez Drosophila melanogaster." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT045/document.

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Le cerveau de drosophile est constitué entre autres des mushroom body, siège de la mémoire et de l’apprentissage. Cette structure est composée de différents types de neurones, parmi lesquels les neurones /. Ces neurones se présentent sous une forme orthogonale, avec l’axone qui se divise en une branche dorsale : la branche et une branche médiale : la branche . Le but de cette étude est de comprendre les mécanismes et voies de signalisation mis en jeu lors du développement de ces neurones.Chez la drosophile, la protéine APPL (Amyloïd Precursor Protein-Like) est l’homologue de la protéine APP hu
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Buscarlet, Manuel. "The neural progenitor to neuron transition : role and regulation of GrouchoTLE proteins." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115670.

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Groucho/transducin-like Enhancer of split (Gro/TLE) family proteins are corepressors found as part of multiple transcriptional complexes that play significant roles during many developmental processes, including neurogenesis. This thesis sought to characterize the molecular mechanisms underlying the biological activity of Gro/TLE1. More specifically, the aim was to clarify the contribution of different transcriptional cofactors, as well as phosphorylation events induced by cofactor binding, to Gro/TLE1 ability to inhibit neuronal differentiation from proliferating neural progenitor cells.<br>B
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Kwok, Alice. "Unfolded protein responses in models of Motor Neuron Disease." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:2f3efba7-dce1-4521-bda6-4db8ee81094d.

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Motor neuron disorders are a heterogeneous group of diseases characterized by the selective degeneration of motor neurons leading to muscle wasting and atrophy. Amyotrophic Lateral Sclerosis (ALS) is the most common amongst these disorders and is characterized by the selective loss of both upper and lower motor neurons in the brain and spinal cord. 20% of familial cases of ALS are caused by mutations in the Cu, Zn-superoxide dismutase gene (SOD1), a ubiquitously expressed enzyme responsible for scavenging superoxide radicals. The exact mechanisms underlying mutant SOD1-mediated neurotoxicity a
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Charoy, Camille. "Mécanismes moléculaires de polarisation des projections neuronales dans l'axe droite-gauche." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10090/document.

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Les circuits nerveux s'organisent autour des grands axes de polarité du corps. Au cours du développement, la navigation ainsi que l'arrangement spatial des projections au sein de leurs territoires cibles sont contrôlés par de nombreux facteurs de guidage. Pendant ma thèse je me suis intéressée à deux modèles de formation des circuits neuronaux présentant une polarité dans l'axe droite-gauche. Le premier concerne la mise en place des projections des interneurones commissuraux de la moelle épinière, un modèle de navigation orientée et le second, porte sur l'innervation des motoneurones phrénique
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35

Zhang, Donghao. "Automatic Neuron Reconstruction Based on 3D Microscopic Images." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15390.

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The digital reconstruction of single neurons from 3D microscopic images plays an important role for understanding the neuron morphology and function. However the accurate automatic neuron reconstruction remains a challenging task due to the varying image quality and the complexity in the arborisation of neurons. In this thesis, a novel automatic neuron reconstruction framework is proposed with image enhancement pipelines, soma volume reconstruction and neuron tree tracing. A Neuron Stalker algorithm is first designed to trace the neuronal tree structure based on local gradient vector flows. A
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Cellot, Giada. "Towards new generation of neuro-implantable devices : engineering neuron/carbon nanotubes integrated functional units." Doctoral thesis, Università degli studi di Trieste, 2010. http://hdl.handle.net/10077/3663.

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2008/2009<br>Le nanotecnologie sono un campo delle scienze che utilizza materiali e dispositivi ingegnerizzati aventi la più piccola organizzazione funzionale a livello di dimensioni nanometriche. Questo implica che nanodispositivi e nanomateriali possano interagire con i sistemi biologici a livello molecolare con un elevato grado di specificità. É largamente accettato che l’applicazione delle nanotecnologie nell’ambito delle neuroscienze abbia un forte potenziale (Silva, 2006). In questo contesto, i nanotubi di carbonio (CNT), un’innovativa forma di carbonio composta da strutture tubulari di
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Aron, Liviu. "Genetic analysis of dopaminergic neuron survival." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-117874.

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Shivji, Nadia. "GnRH neuron migration during embryonic development." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611556.

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Echanique, Christopher. "Characterization of an advanced neuron model." Honors in the Major Thesis, University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/547.

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This thesis focuses on an adaptive quadratic spiking model of a motoneuron that is both versatile in its ability to represent a range of experimentally observed neuronal firing patterns as well as computationally efficient for large network simulation. The objective of research is to fit membrane voltage data to the model using a parameter estimation approach involving simulated annealing. By manipulating the system dynamics of the model, a realizable model with linear parameterization (LP) can be obtained to simplify the estimation process. With a persistently excited current input applied to
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40

Serene, Stephen Rothrock. "Generative probabilistic models of neuron morphology." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/85494.

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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (page 40).<br>Thanks to automation in ultrathin sectioning and confocal and electron microscopy, it is now possible to image large populations of neurons at single-cell resolution. This imaging capability promises to create a new field of neural circuit microanatomy. Three goals of such a field would be to trace multi-cell neural networks, to classify neurons into morphological cell types, and to
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41

Le, Roux Peter David. "Neuron-glial interactions in dendrite growth." Doctoral thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/27039.

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Interactions between neurons and glia occupy a central role in many aspects of development, maintenance, and function of the central nervous system (CNS). A fundamental event in CNS development is the elaboration of two distinct neuronal processes, axons and dendrites. The overall aim of this research was to characterize the interactions between central nervous system neurons and astroglial cells that regulate dendrite growth from cerebral cortical neurons. Embryonic (E18) mouse cerebral cortical neurons were cocultured with early postnatal (P4) rat astroglia derived from cerebral cortex, reti
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42

Luo, Jiafu Psaltis Demetri. "Monolithic GaAs VLSI optoelectronic neuron arrays /." Diss., Pasadena, Calif. : California Institute of Technology, 1996. http://resolver.caltech.edu/CaltechETD:etd-05012006-124513.

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43

Williams, David Bruce. "Genetic factors in motor neuron disease." Thesis, The University of Sydney, 1989. https://hdl.handle.net/2123/26235.

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The term motor neuron disease is used by different authors to designate one or more of a wide variety of disorders whose principal common feature is dysfunction of the motor neuron (MN) or anterior horn cell (AHC). In one convention, the term motor neuron disease is used to denote all such disorders, including both infantile- and juvenile-onset forms of spinal muscular atrophy, and corticospinal degenerations in which the upper motor neuron is prominently affected. At other times the term motor neuron disease refers only to the relatively common and presumably more homogeneous condition which
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Orsetti, Valeria. "Pathogenetic mechanisms in motor neuron diseases." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3421997.

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Amyotrophic Lateral Sclerosis, ALS, and Spinal and Bulbar Muscular Atrophy, SBMA (or Kennedy’s disease, KD) are two rare degenerative disorders of nervous system, characterized by early involvement of motor neurons. ALS is characterized by degeneration and death of upper and lower motor neurons, which leads to generalized muscle weakness and atrophy, speech and swallowing disabilities, and progressive paralysis until death is caused by respiratory failure. Its pathogenesis is still unknown. KD is an inherited X-linked motor neuronal disorder caused by an abnormal expansion of a trinucleotide C
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45

Bäumer, Dirk. "Functional genetic analysis of motor neuron disease." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:859016f8-5eff-4a8e-bfda-48afb8695646.

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Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the commonest motor neuron diseases of adult- and childhood onset. Alterations of the RNA binding protein TDP-43 are associated with most cases of ALS, while SMA is caused by deletion of the Survival Motor Neuron (SMN1) gene. SMN has been well characterised in its role in the assembly of the cellular machinery that carries out splicing of pre-mRNA, but is thought to have other functions in RNA metabolism unrelated to pre-mRNA splicing. It is conceivable that specific aspects of RNA handling are disrupted in both SMA and
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Vik, Lukas, and Fredrik Svensson. "Real-time stereoscopic object tracking on FPGA using neural networks." Thesis, Linköpings universitet, Institutionen för systemteknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-110374.

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Real-time tracking and object recognition is a large field with many possible applications. In this thesis we present a technical demo of a stereoscopic tracking system using artificial neural networks (ANN) and also an overview of the entire system, and its core functions. We have implemented a system able of tracking an object in real time at 60 frames per second. Using stereo matching we can extract the object coordinates in each camera, and calculate a distance estimate from the cameras to the object. The system is developed around the Xilinx ZC-706 evaluation board featuring a Zynq XC7Z04
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Monani, Umrao Raj. "Motor neuron genes : a comparison of the centromeric and telomeric survival motor neuron (SMNc and SMNt) genes /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487951907957402.

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Erasmus, Louwrence Daniel. "The formulation and evaluation of a neuron model based on biological neurons / Louwrence Daniël Erasmus." Thesis, North-West University, 2007. http://hdl.handle.net/10394/2307.

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This thesis formulates and evaluates a mathematical model from an engineer's point of view based on the currently-known information-processing processes and structures of biological neurons. The specification and evaluation of the RealNeuron model form a baseline for current use in engineering solutions and future developments. The RealNeuron is a carefully-reduced model that retains the essential features of more complex models. A systems engineering approach is used to formulate it, i.e. the model is described as using multiple resolution levels with configurable modular elements at each re
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Mahoney, Sally-Ann. "A role for tissue transglutaminase in neuron / glial interaction and development of cerebellar granule neurons." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361111.

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Habrnál, Matěj. "Hluboké neuronové sítě." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2014. http://www.nusl.cz/ntk/nusl-236132.

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The thesis addresses the topic of Deep Neural Networks, in particular the methods regar- ding the field of Deep Learning, which is used to initialize the weight and learning process s itself within Deep Neural Networks. The focus is also put to the basic theory of the classical Neural Networks, which is important to comprehensive understanding of the issue. The aim of this work is to determine the optimal set of optional parameters of the algori- thms on various complexity levels of image recognition tasks through experimenting with created application applying Deep Neural Networks. Furthermor
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