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Dissertations / Theses on the topic 'Neuropeptides'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Brumovsky, Pablo R. "Neuropeptides, sensory neurons and pain modulation /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-442-2/.

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2

Duroux, Stéphane. "Neuropeptides et muqueuse nasale." Bordeaux 2, 1994. http://www.theses.fr/1994BOR23014.

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3

Pheng, Leng-Hong. "Caractérisation pharmacologique des récepteurs natifs du neuropeptide Y et de la nociceptine." Sherbrooke : Université de Sherbrooke, 2001.

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4

Diez, Margarita. "Neuropeptide expression in mouse disease models /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-514-x/.

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5

Guery, Sébastien. "Conception et synthèse de dérivés de l'arginine : Concepts et validation sur des récepteurs de neuropeptides." Université Louis Pasteur (Strasbourg) (1971-2008), 2003. https://publication-theses.unistra.fr/public/theses_doctorat/2003/GUERY_Sebastien_2003.pdf.

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La découverte de neuropeptides comme molécules pharmacologiquement actives est d'une importance considérable pour notre compréhension de la neurobiologie. Les neuropeptides peuvent agir en tant que neurotransmetteurs, neuromodulateurs et en tant qu'hormones. Ils contrôlent ou influencent de nombreux types de comportements biologiques (par exemple le comportement sexuel, le comportement alimentaire, la mémoire, l'apprentissage, la perception de la douleur, ). Certains de ces peptides appartiennent à la famille des peptides de type RF-amide qui possèdent dans leur partie C-terminale un résidu Ar

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6

Bjellerup, Per. "Biochemical characterisation and clinical correlation of neuropeptides in neuroblastoma with emphasis on neuropeptide Y /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4524-1/.

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7

Lodge, Daniel 1977. "Neuropeptides, anxiety and alcoholism." Monash University, Dept. of Pharmacology, 2002. http://arrow.monash.edu.au/hdl/1959.1/7706.

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8

Ostlere, Lucy Sinclair. "Neuropeptides in atopic dermatitis." Thesis, Queen Mary, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267167.

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9

Di, Marzo V. "Neuropeptides and leukotriene biosynthesis." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/47024.

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10

Dubin, Thierry. "Le neuropeptide Y dans le phéochromocytome : étude à partir d'une série de 15 cas." Bordeaux 2, 1990. http://www.theses.fr/1990BOR23098.

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11

Morgan, David Alexander. "The role of neuropeptides Y and neuropeptide Y receptors in the control of carbohydrate metabolism." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267076.

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12

Morgat, Clément. "Imagerie des récepteurs de neuropeptides pour le ciblage tumoral." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0308/document.

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Des récepteurs de neuropeptides peuvent être fortement exprimés à la surface descellules tumorales offrant ainsi l’opportunité de les visualiser en imagerie par Tomographie d'Emissionde Positons (TEP) grâce à des analogues radiomarqués au 68Ga, 64Cu ou au 18F, mais également desélectionner des patients répondeurs à une radiothérapie métabolique à l'aide de ces mêmes analogues,radiomarqués au 177Lu ou 90Y. Un exemple phare a été le développement d’analogues radiomarqués dela somatostatine pour l'imagerie (68Ga-DOTATOC) et le traitement (177Lu-DOTATATE) des tumeursneuro-endocrines (TNE). Cette v

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13

Appelgren, Anna. "Neuropeptides in temporomandibular joint arthritis /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3893-8/.

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14

Leung, Po Sing. "Studies on some molluscan neuropeptides." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333802.

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15

Dougan, P. M. "Molecular studies on platyhelminth neuropeptides." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391110.

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16

Marshall, Anna K. "Myoactive neuropeptides in Manduca sexta." Thesis, University of Bath, 1995. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307029.

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17

Ehrström, Marcus. "Studies on the effect of orexin on upper gastrointestinal function in rats and man /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-957-9/.

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18

Duerr, Heike Edith. "Molecular characterisation of neuropeptides in echinoderms." Thesis, Royal Holloway, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314294.

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19

Littlewood, Gillian Mary. "Characterisation of membrane peptidases inactivating neuropeptides." Thesis, University of Leeds, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236308.

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20

Terry, Adrian Simon. "Studies on the biosynthesis of neuropeptides." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254521.

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21

Ferré, Guillaume. "Dynamique structurale de complexes RCPG - neuropeptides." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30141.

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Les récepteurs couplés aux protéines G (RCPG) reconnaissent un ligand extracellulaire afin de transmettre l'information correspondante à l'intérieur de la cellule. Ils sont des acteurs prépondérants en physiologie ainsi que des cibles pharmacologiques majeures. Nous avons étudié deux RCPG dont les ligands endogènes sont des peptides. a) Le récepteur ĸ opioïde (KOP) qui reconnait la dynorphine. Ce récepteur joue un rôle fondamental dans la régulation de la douleur et des mécanismes de récompense (et donc dans l'addiction). La découverte, la pharmacologie et les relations structure - fonction de

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22

Ho, Chi-wang John, and 何志泓. "Molecular characterization of chicken galanin and galanin receptor family." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47752646.

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Galanin is a multi-functional neuropeptide with widespread distribution in the central and peripheral nervous systems of different species. It exerts a broad spectrum of physiological functions through the interactions with three galanin receptor subtypes namely the GalR1, GalR2 and GalR3, which have only been identified in mammals. In contrast to the extensive studies in mammals, little is known about the structures and functions of galanin and its receptors in avian species. In the present study, a total of nine chicken cDNAs including four galanin prepropeptide transcript variants (cGal

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23

Phan, Toan Anh. "Ocular immunomodulating neuropeptides alpha-MSH and neuropeptide Y modulate phagocytic activity of the microphage cell line RAW 246.7." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12591.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>The eye is an immune privileged tissue. Within the ocular microenvironment, there are regulatory mechanisms that suppress inflammation. These anti-inflammatory mechanisms are partly mediated by immunomodulating

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24

De, Joydeep. "Les signaux quotidiens et saisonniers modulent la configuration du réseau neuronal d'horloge circadienne." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS256.

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L'omniprésence des horloges circadiennes à travers une vaste gamme de taxons démontre la valeur adaptative de connaître l'heure du jour. Ces horloges permettent aux organismes de synchroniser leurs processus biologiques quotidiens à des environnements externes et internes changeants. Dans mon projet de doctorat, j'ai utilisé la drosophile comme système modèle pour étudier les bases neurales de l'adaptation saisonnière de l'activité quotidienne par l'horloge. Chez la drosophile, l'horloge cérébrale régulant l'activité locomotrice, suivant un modèle bimodale, fonctionne comme un réseau multi-osc

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25

Lin, Ming. "Identification and functional characterization of relaxin-type and pedal peptide/orcokinin-type neuropeptides in the starfish Asterias rubens." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/30715.

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Neuropeptides are neuronal signaling molecules that regulate many physiological and behavioural processes in vertebrates and invertebrates. Investigation of neuropeptide signaling in echinoderms (e.g. starfish) can provide insights into the evolution of neuropeptide systems because as deuterostomian invertebrates they occupy an "intermediate" phylogenetic position between vertebrates and protostomian invertebrates. Recent analysis of neural transcriptome data from the starfish Asterias rubens has identified 40 transcripts encoding neuropeptide precursors. Here the expression and function of ne

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26

Moller, Kristian. "Pituitary adenylate cyclase activating peptide (PACAP) an experimental study on the expression and regulation in the peripheral nervous system /." Lund : Dept. of Physiology and Neuroscience, neuroendocrine Cell Biology, Lund University, 1997. http://books.google.com/books?id=Fw5rAAAAMAAJ.

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27

Chaloin, Olivier. "Synthèse d'analogues peptidiques et pseudopeptidiques du neuropeptide Y." Montpellier 2, 1996. http://www.theses.fr/1996MON20100.

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Ce travail est consacre a la synthese d'analogues peptidiques et pseudopeptidiques du neuropeptide y. Une etude sur les relations structure-activite a ete developpee. Dans un premier temps, nous avons synthetise des analogues modifies au niveau du pentapeptide c terminal par des substitutions d'aminoacides et introduction de liaisons pseudopeptidiques. Dans une deuxieme partie, nous avons synthetise des analogues dimerises de la partie c terminale du neuropeptide y. La derniere partie de ce travail a ete la synthese d'analogues du bibp 3226, un puissant antagoniste selectif des recepteurs y1 d

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28

Kadri-Guissi, Sanae. "Expression de gènes spécifiant des précurseurs de neuropeptides, chez un ver marin, Nereis diversicolor." Lille 1, 1989. http://www.theses.fr/1989LIL10060.

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Caractérisation des précurseurs de la cholecystokinine, de la dymorphine 1-17 et de l'-neo-endorphine par traduction in vitro et in ovo des ARN messagers isolés du cerveau de n-diversicolor et à l'aide d'anticorps spécifiques

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29

Tuzmen, Ceren. "Regulation of Bone Differentiation Through the Neuropeptides." Research Showcase @ CMU, 2017. http://repository.cmu.edu/dissertations/1083.

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This dissertation aims to demonstrate immunoregulatory roles of neuropeptides in bone metabolism both in bone and non-bone microenvironments. Substance P (SP) and calcitonin gene-related peptide (CGRP) are sensory neuropeptides that have been associated with various aspects of the pathophysiology of heterotopic ossification (HO) of soft tissues. These aspects include dysregulation of inflammation, mainly governed by macrophages and mast cells, and bone morphogenetic protein (BMP) signaling. The first set of experiments presented here contributes to the understanding of the involvement of the n

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30

Aromataris, Edoardo Claudio. "Opioid neuropeptides in the guinea-pig heart /." Title page and summary only, 1994. http://web4.library.adelaide.edu.au/theses/09SB/09sba769.pdf.

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31

Wozniak, Andrzej. "The role of neuropeptides in inflammatory disease /." Title page, contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phw938.pdf.

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Thesis (Ph. D.)--University of Adelaide, Dept. of Medicine, 1993.<br>Copies of author's previously published articles inserted. Amendments (2 leaves) in front cover pocket. Includes bibliographical references (leaves 227-259).

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32

Abusnana, Salahedeen Emhemed Elmansuri. "Hypothalamic neuropeptides in regulation of feeding behaviour." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391263.

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33

Jenkins, D. W. "Prostaglandins and neuropeptides in rat trigeminal neurones." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.605089.

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Having identified prostaglandin receptors in trigeminal tissue, the functional effects of prostaglandin receptor ligands on CGRP release were investigated using cultured adult rat trigeminal ganglion neurones as a model system. It was found that calcium-dependent CGRP release could be stimulated following stimulation of DP, EP and IP receptors. Furthermore, the use of EP receptor specific agonists and antagonists suggested that the EP receptor subtype involved might be the EP<sub>2</sub> receptor. The effects of several agents on prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) release from the c

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34

Eedy, David John. "Neuropeptides in skin in health and disease." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335268.

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35

Moffett, C. L. "Structural and functional characterization of nematode neuropeptides." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390877.

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36

Hooper, Nigel Mark. "Metabolism of neuropeptides by cell-surface peptidases." Thesis, University of Leeds, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235486.

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37

Khan, Mohamed Michael Tariq. "Neuropeptides and cytokines in regenerating peripheral nerve." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243451.

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38

Rowe, Matthew Lyndon. "Structure and function of sea urchin neuropeptides." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/599.

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The subject of this thesis is the identification and functional characterization of sea urchin neuropeptides. Neuropeptides are important mediators of neural signalling in all known animals with a nervous system, including bilaterians, ctenophorans, and cnidarians. Sea urchin neuropeptides are of particular interest for three significant reasons; echinoderms have a radically different secondarily-derived pentaradial body structure, sea urchins have served as model organisms for research into embryonic development, and thirdly because the genome of a sea urchin, the purple sea urchin Strongyloc

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39

Jones, Christine Ann. "Monoclonal antibodies in the study of neuropeptides." Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/46848.

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40

Augé, Sophie. "Topographie intramembranaire de neuropeptides : quelques approches membranaires." Toulouse 3, 1996. http://www.theses.fr/1996TOU30125.

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La conformation membranaire d'un neuropeptide peut etre determinee par la technique rmn de l'effet overhauser nucleaire transfere (trnoe), a partir du peptide en interaction avec des liposomes constitues de phospholipides perdeuteries. Une souche de levure methylotrophe, pichia angusta, a ete adaptee a la croissance en milieu perdeuterie. Ceci a permis d'isoler des phospholipides (130 mg), des glycolipides et de l'ergosterol (30 mg) perdeuteries a 97,5%, a partir d'une culture en fermenteur de 1,5 l (24 gde matiere seche). L'etude de la neurokinine a (nka) par trnoe a ete entreprise apres l'at

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41

Smith, Gary D. "Steroid regulation of neuropeptides in sensory neurons." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/20198.

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Primary afferent neurons with perikarya in the dorsal root ganglia (<i>drg</i>) mediate the transmission of sensory information from the periphery and viscera to the spinal cord. A number of neuropeptides, including substance P (SP), somatostatin (SS) and calcitonin gene related peptide (CGRP) have been localised in discrete but often overlapping subpopulations of <i>drg</i> neurons. These neuropeptides have been implicated in nociception and neurogenic inflammation, both processes which can be influenced by steroid hormones. Whilst steroid hormones have been shown to regulate synthesis of a n

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42

Jinsmaa, Yunden. "Designing of Novel Neuropeptides Improving Learning Performance." Kyoto University, 1999. http://hdl.handle.net/2433/181886.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第7877号<br>農博第1035号<br>新制||農||776(附属図書館)<br>学位論文||H11||N3240(農学部図書室)<br>UT51-99-G471<br>京都大学大学院農学研究科食品工学専攻<br>(主査)教授佐々木隆造, 教授吉川正明, 教授伏木亨<br>学位規則第4条第1項該当

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43

Xu, Isabella Shi. "The role of neuropeptides in spinal nociceptive mechanisms with special emphasis on galanin, neuropeptide Y and orphanin FQ/nociceptin /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-3973-X/.

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44

Tousignant, Christine. "Effets des neuropeptides sur le système nerveux autonome." Mémoire, Université de Sherbrooke, 1987. http://hdl.handle.net/11143/11703.

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Les neurokinines et les kinines sont de puissants stimulants des vas deferens de rat, de lapin et de cobaye : elles augmentent l'effet de la stimulation électrique de base en facilitant la libération du ou des neurotransmetteur(s) qui activent les récepteurs musculaires. Les sites réceptoriels pré et postsynaptiques ont été étudiés séparément dans les vas deferens alors que cette distinction n'a pas été possible pour l'artère pulmonaire de lapin stimulée. La partie prostatique des vas deferens a été utilisée pour étudier le ou les sites préjonctionels alors que la partie épididymale s'est révé

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45

Moheimen, Jamil. "Striatal neuropeptides associated with L- DOPA-induced dyskinesia." Thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-209915.

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Abstract Striatal neuropeptides associated with L-DOPA-induced dyskinesia 2012-02-14 <img src="file:///page2image2248" /> Parkinson's disease (PD) is the most common neurodegenerative disease, with approximately 6 million sufferers in the world. The patients are usually diagnosed between the ages 50-70 years and as the disease progress more symptoms may occur. The cause of the disease is unknown, but the characteristic of PD is that it is a selective degeneration of dopaminergic neurons in the substantia nigra, which leads to an absence of dopamine release in striatum. This affects the motor s

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46

Ward, Helen Louise. "Novel neuropeptides, feeding and the hypothalmo-pituitary axes." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405173.

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47

Roy, Debabrata. "The role of hypothalamic neuropeptides in energy homeostasis." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520830.

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48

Mousley, A. "Cross-phyla studies of helminth and arthropod neuropeptides." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368480.

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49

Williamson, Stanley Alexander. "Modulation of herpes virus specific immunity by neuropeptides." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/47303.

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50

Wang, Zunyi. "Physiology and pharmacology of C-fibres in the rabbit eye." Lund : Dept. of Pharmacology, University of Lund, 1996. http://catalog.hathitrust.org/api/volumes/oclc/39783537.html.

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