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Journal articles on the topic 'Nitric oxide (NO) scavenging activities'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Palani, Kokila, Nithya Palaniappan, Saranya Karuppannan, Archana Lakshmanan, Viji Maluventhan, and Maruthupandian Arumugam. "Proximate composition and physicochemical properties of Red seaweed Hypnea valentiae (Turnur) and their potential of antioxidant activities." International Journal of Zoology and Applied Biosciences 7, no. 5 (2022): 19–24. http://dx.doi.org/10.55126/ijzab.2022.v07.i05.sp003.

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The present study focused on proximate composition, moisture, ash, lipid, protein, carbohydrate, dietary fiber and physicochemical properties to determine the water holding capacity, oil holding capacity, and water swelling capacity of H. valentiae red seaweed. The antioxidant properties of methanol extract were performed by superoxide and nitric oxide radical scavenging activity. The superoxide scavenging radical (50-250 μg/mL) was an inhibition of 89.06 ± 0.44μg/mL which is significantly higher than the standard ascorbic acid 75.67 ± 0.20μg/mL. Nitric oxide assay observed that (15-100 μg/mL)

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2

Wang, Min, Chen Xie, Run-Lan Cai, Xiao-Hong Li, Xiu-Zhen Luo, and Yun Qi. "Studies on Antioxidant Activities of Breviscapine in the Cell-Free System." American Journal of Chinese Medicine 36, no. 06 (2008): 1199–207. http://dx.doi.org/10.1142/s0192415x08006521.

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Breviscapine is a commercially produced plant extract from the Chinese herb Erigeron breviscapus. (Vant.) Hand.-Mazz., which contains 2 main flavonoids. It is widely used in clinic to treat ischemic diseases in which free radicals are considered to be the main causal factor. Our study is aimed to examine the antioxidant activity of this extract. The following assays were employed: 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, superoxide anion radical scavenging, nitric oxide radical scavenging, total anti-oxidative capacity, and antilipid peroxidation assays. Breviscapine was demon

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Olaitan, Michael O., Cosmas O. Ujowundu, Chiamaka P. Nzebude, et al. "Organic wastes of Citrus sinensis Peels- a source of eco-friendly and sustainable bioactive compounds for promoting health." Asian Journal of Biochemistry, Genetics and Molecular Biology 16, no. 2 (2024): 21–31. http://dx.doi.org/10.9734/ajbgmb/2024/v16i2358.

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To determine the phytochemicals, radical scavenging and antioxidant potential of orange peel extract. Citrus sinensis were subjected to extraction with ethanol. Gas chromatography (GC) was utilized to determine the phytochemical composition of orange peel extract. Hydrogen peroxide, superoxide, nitric oxide, and hydroxyl radical scavenging assays were conducted to assess radical scavenging potential of the extract. Antioxidant activities of the peel extracts were determined via the 2,2-diphenylpicrylhydrazyl (DPPH) free radical scavenging activity, ferric reducing antioxidant power (FRAP) assa

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4

Ajah, O., C. C. Unegbu, P. O. Alaebo, and C. E. Odo. "Antioxidant Properties and In-Vitro Radical Scavenging Activities of Tannin-Rich and Flavonoid-Rich Fraction of Annona senegelensis and Vernonia amygdalina leaves." Journal of Applied Sciences and Environmental Management 25, no. 10 (2022): 1775–81. http://dx.doi.org/10.4314/jasem.v25i10.5.

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Medicinal Plants have demonstrated history of managing some ailments caused by free radicals as a result of some chemical constituents they possess. This study was aimed at assessing antioxidant and free radical scavenging properties of Tannin-rich and Flavoniod-rich fraction of Annona senegelensis and Vernonia amygdalina leaves via in vitro assays such as; reducing power, nitric oxide scavenging activity, Hydrogen peroxide scavenging activity and Lipid peroxidation scavenging activity. The results obtained indicated that both medicinal plants are antioxidant reservoir. The values for Tannin r

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5

Sabri, Gulnaaz, and Vimala Y. "ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA FLOWERS FROM BIHAR, INDIA." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (2018): 223. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.21976.

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Objective: The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of Leucas aspera flowers.Methods: Antibacterial activity was done by agar diffusion method. The ethyl acetate extract of L. aspera flower was evaluated against both Gram-positive and Gram-negative bacteria. Antifungal activity was also done by agar diffusion method. The agar used for antifungal activity was Czapek Dox Agar. Nitric oxide scavenging assay and free radical scavenging assay were used for the antioxidant activity. Griess reagent was used in nitric oxide scavenging assay. 1,1-diph

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Swami, P. M., P. K. Zubaidha, and G. B. Tiwari. "Synthesis of Novel Nitric Oxide Releasing Furoxan Hybrids from Biologically Active Bicyclic Amine and their Antioxidant Activity." Asian Journal of Chemistry 31, no. 8 (2019): 1724–28. http://dx.doi.org/10.14233/ajchem.2019.21948.

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The present paper describes the synthesis of novel nitric oxide hybrids obtained by linking bioactive bicyclic amine to substituted furoxans. The antioxidant activities were studied in vitro based on the radical scavenging effect of stable DPPH free radical using ascorbic acid as a standard. The nitric oxide hybrids showed remarkable antioxidant properties and hence, can be employed as potential antioxidant agents.

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Venkatachalam, Suresh kumar Tirupur, SenthilKumar Palanisamy, Sudhagar Babu та Ranjithkumar Rajamani. "Assesment of free radical scavenging activity and inhibitory properties of aqueous extract of Cymodocea serrulata segrass towards α- glucosidase and α –amylase enzyme". Journal of University of Shanghai for Science and Technology 23, № 12 (2021): 339–60. http://dx.doi.org/10.51201/jusst/21/121035.

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Aim: The study reports the in vitro free radical scavenging and α-amylase and α-glucosidase inhibition activities of aqueous extract of seagrass Cymodocea serrulata from Gulf of Mannar, Southeast Asia. Methods: The free radical scavenging activity was evaluated by DPPH, Superoxide, Nitric oxide and Hydroxyl radical scavenging assays and α-amylase, α-glucosidase enzyme inhibitory activity. The C. serrulata showed effective DPPH radical scavenging activity of 69.45 μg/mL, Superoxide radical scavenging activity of 91.08.5 ± 0.02%, Nitric oxide radical scavenging activity of 86.89 ± 0.03% and Hydr

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8

T, Satapathy. "Pre-Clinical Evaluation for Anti-Inflammatory, Antioxidant and Antibacterial Potential of Boswellia seratta." Advances in Pharmacology and Clinical Trials 8, no. 4 (2023): 1–5. http://dx.doi.org/10.23880/apct-16000225.

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Objective: The present study was undertaken to evaluate the anti-inflammatory, anti-oxidant and antibacterial potential of Boswellia serrata extract. Methods: Antioxidant activity was determined using DPPH, Hydroxyl, and Total antioxidant capacity and nitric oxide radical scavenging activities. Anti-inflammatory activity was determined using hyaluronidase enzyme inhibitory assay in which Indomethacin was taken as a reference drug. Agar diffusion was used as a test for antibacterial activity. Grampositive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria were chosen for the

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Abdallah, Hossam M., Noha Z. Timraz, Sabrin R. M. Ibrahim, et al. "Nitric-Oxide-Mediated Vasodilation of Bioactive Compounds Isolated from Hypericum revolutum in Rat Aorta." Biology 10, no. 6 (2021): 541. http://dx.doi.org/10.3390/biology10060541.

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Vasodilators are an important class in the management of hypertension and related cardiovascular disorders. In this regard, the chloroform fraction of Hypericum revolutum (HR) has been reported to produce vasodilating activity in phenylephrine-precontracted aortae. The current work aims to identify the active metabolites in the chloroform fraction of HR and illustrate the possible mechanism of action. The vasodilation activities were investigated using the isolated artery technique. NO vascular release was assessed by utilizing the NO-sensitive fluorescent probe DAF-FM. Free radical scavenging

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10

Devi, Khoirom Ratipiyari, Paonam Priyobrata Singh, Moirangthem Medhapati Devi, and Gurumayum Jitendra Sharma. "Evaluation of Antioxidant Activities of Alpinia galanga (L.) Willd." Biosciences Biotechnology Research Asia 15, no. 4 (2018): 899–908. http://dx.doi.org/10.13005/bbra/2700.

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Present research was designed to evaluate the free radical scavenging capacities and antioxidant activities of rhizome extracts of Alpinia galanga prepared in different solvent systems (60% aqueous methanol, 60% aqueous ethanol and distilled water) using different in vitro chemical assays. Antioxidant components such as total phenolic content (TPC), total flavonoid content (TFC) and ascorbic acid contents of the ginger species were screened. Antioxidant assays employed included sulphur free radical reactivity assay, ferric ion reducing power assay, DPPH free radical scavenging capacity assay,

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Gana, Manjusha K. 1. *. Dr. Ganga Rao B. 2. "SCREENING OF IN VITRO ANTIOXIDANT ACTIVITY OF SELECTED FRUIT PEELS: A COMPARATIVE STUDY." Journal of Pharma Research 7, no. 10 (2018): 227–30. https://doi.org/10.5281/zenodo.1471138.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he present was planned to evaluate the in vitro antioxidant activity of selected peel powers such as </em><em>Annona sqaumosa, Actinidia deliciosa, Cucumis melo and Mallus pumila </em><em>using different in vitro assays including the scavenging activities of hydroxyl radical, hydrogen peroxide, Nitric oxide and DPPH radical scavenging activities. The antioxidant activity of peels was compared with standard antioxidant rutin. The comparative study resulted that the Mallus pumila showed better antioxidant activity against the hydr

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Lee, Hee-kyung, and Kwan-jong Yu. "Anti-inflammatory and antioxidant activities of Pleurotus nebrodensis extract : application in a functional tea." Association for International Tea Culture 65 (September 30, 2024): 165–92. http://dx.doi.org/10.21483/qwoaud.65..202409.165.

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This study was designed to examine the nitric oxide production, hyaluronidase, and prostaglandin E2 (PGE2) inhibitory activities for the anti-inflammatory effect and DPPH and ABS radical scavenging activities for antioxidant effect using Pleurotus nebrodensis mycelium extract for a functional tea development. The cell viability was confirmed that all extracts were not cytotoxic to RAW264.7 cell within a concentration of 90 μg/mL irrespective of solvent extracts. The nitric oxide inhibitory activity in LPS-stimulated RAW264.7 cells was the highest at 43.6% using 90 μg/mL of hot water extract. T

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Prabhakaran D, Rajeshkanna A, and Senthamilselvi M M. "Antioxidant and Anti-inflammatory activities of the flower extracts of Argemone mexicana L." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 323–30. http://dx.doi.org/10.26452/ijrps.v11i1.1824.

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To assess the antioxidant and anti-inflammatory activities of the powder sample derived from the ethyl acetate fraction of the floral Argemone mexicana L. For antioxidant efficiency, the floral extract was evaluated using 1, 1–diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay and the FRC (Ferric Reduction Capacity) assay. In vitro anti-inflammatory activity was assessed using human peripheral blood mononuclear cells (PBMC) induced by lipopolysaccharide (LPS) and the production method of nitric oxide (NO). The powder sample extracted from ethyl acetate fraction of the floral of Argemon

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14

E. C., Moneme,, Onochie, A. U., Onuegbu, M. E., Anyanwu, R. O., Ajakpofo, F. O., and Oladejo, A. A. "In vitro Antioxidant Activity and Free Radical Scavenging Abilities of Ocimum gratissimum Leaf Extract." Journal of Advances in Medical and Pharmaceutical Sciences 27, no. 3 (2025): 54–63. https://doi.org/10.9734/jamps/2025/v27i3758.

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In recent years, researchers have intensified the search for effective, non-toxic, natural edible plants with free radical scavenging activity whose effects are cushioned by antioxidant molecules. This study evaluated the in vitro antioxidant activity and free radical scavenging abilities of Ocimum gratissimum leaf extract. In vitro antioxidant (nitric oxide, Hydrogen Peroxide, Ferric Reducing property and DPPH) activities were determined using standard methods. Results showed that the leaf extract of Ocimum gratissimum considerably scavenges radicals of nitric oxide, hydrogen peroxide and DPP

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15

Oriakhi, Kelly, Kissinger Orumwensodia, and Patrick Uadia. "Phytochemical Investigation and In Vitro Antioxidant Activities of Tetracarpidium conophorum (African Walnut) Seeds." Avicenna Journal of Medical Biochemistry 6, no. 2 (2018): 56–61. http://dx.doi.org/10.15171/ajmb.2018.12.

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Background: Tetracarpidium conophorum (African walnut) is an African plant with ethnobotanical uses. Objectives: The purpose of this study was to evaluate the phytochemical screening and in vitro antioxidant activities of methanol extract and fractions (F) [n-hexane (HEX-F), dichloromethane (DCM-F) and, ethyl acetate (EA-F)] of T. conophorum seeds. Methods: Phytochemical screening and in vitro antioxidant activity study were carried out using DPPH, ABTs radical scavenging assays, nitric oxide inhibitory and reducing potential assays. Results: Methanol extract and its fractions contain phenols,

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16

Tu, Ansari Imtiyaz Ahmed, Qazi Majaz Ahamad Aejazuddin, G. J. Khan, et al. "Unani Formulation Habb-e-Suranjan: A Treasure of Biological Activities." BioMed Research International 2022 (July 26, 2022): 1–11. http://dx.doi.org/10.1155/2022/1640193.

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Habb-e-Suranjan (HES), an Unani formulation, has been studied for its anti-inflammatory properties in both in vitro and in vivo experiments. HES is recommended for arthritis, gout, and joint pain. The current endeavor is an attempt to put it to the test and verify its efficacy scientifically. It was tested for DPPH, hydroxyl, and nitric oxide scavenging activities. It was shown that HES had the greatest TAC and FRAC values when compared to catechin and ascorbic acid. HES exhibited DPPH and hydroxyl radical scavenging activity that was dose-dependent. Incubation of sodium nitroprusside solution

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17

Sulaimon, Lateef Adegboyega, Fausat Kikelomo Ola-Mudathir, Bunyamin Alhassan Abdullahi, Ahmad Ila Mukhtar, and Efere Martins Obuotor. "A Comparative Study on Antioxidant and Cytotoxic Potentials of Methanol Extract of Jatropha curcas Seeds and Leaves." Journal of Drug Delivery and Therapeutics 11, no. 6-S (2021): 43–48. http://dx.doi.org/10.22270/jddt.v11i6-s.5220.

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Many medicinal plants have been reported to exhibit protective effects against many physiological diseases as a result of their phytochemical components which are effective antioxidants. This study was aimed at comparing the phenolic and flavonoids contents, antioxidant and cytotoxic activities of methanol extract of Jatropha curcas seeds and leaves. The cytotoxicity level of J. curcas was assessed using the brine shrimp lethality test (BSLT). The antioxidant activity was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, ferric reducing antioxidant power (FRAP), n

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18

ALIPOUR, B. S., M. A. EBRAHIMZADEH, B. ESLAMI, and Z. RAHMANI. "ANTIOXIDANT ACTIVITIES OF HYPERICUM FURSEI L." Latin American Applied Research - An international journal 44, no. 1 (2014): 19–23. http://dx.doi.org/10.52292/j.laar.2014.414.

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In this study, antioxidant activities of H. fursei were investigated. Different model were used for assay. IC50 for DPPH radical-scavenging activity was 7.5±1.2 μg ml-1. The IC50 value for BHA was 92.9±4.5 µg ml-1. The extract showed very good reducing power that was comparable with vitamin C (p> 0.05) but showed weak nitric oxide scavenging activity and Fe2+ chelating ability. Extract showed good activity in scavenging of H2O2. Inhibition was 99.1% at 800 μg ml-1. The IC50 values for extract and BHA were 333.1±14.7 and 52.0±4.5 μg ml-1, respectively. Total phenol compounds, by the Folin Ci

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Swathi, Naraparaju, and Thirumurthy Durai Ananda Kumar. "Insights into Thiazolidinedione Analogues: Unveiling Antioxidant Activity through Descriptor-Based Quantitative Structure-Activity Relationship Investigations." Asian Journal of Applied Chemistry Research 15, no. 1 (2024): 1–11. http://dx.doi.org/10.9734/ajacr/2024/v15i1277.

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Background: Diabetes mellitus, a chronic metabolic disorder is characterized by defective insulin secretion (β-cell dysfunction), insulin action (insulin resistance) and reduced bio-antioxidant potential. Antioxidants play key role in diabetes by reducing the oxidative stress and alleviating diabetic complications. Thiazolidinediones (TZDs) attenuate insulin resistance and produce antioxidant effect. Study Design: In continuation of our goal to develop thiazolidine-2,4-dione analogues that can address both oxidative stress and Type 2 diabetes, the in vitro antioxidant potential of a few synthe

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Ukeri, John, Michael T. Wilson, and Brandon J. Reeder. "Modulating Nitric Oxide Dioxygenase and Nitrite Reductase of Cytoglobin through Point Mutations." Antioxidants 11, no. 9 (2022): 1816. http://dx.doi.org/10.3390/antiox11091816.

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Cytoglobin is a hexacoordinate hemoglobin with physiological roles that are not clearly understood. Previously proposed physiological functions include nitric oxide regulation, oxygen sensing, or/and protection against oxidative stress under hypoxic/ischemic conditions. Like many globins, cytoglobin rapidly consumes nitric oxide under normoxic conditions. Under hypoxia, cytoglobin generates nitric oxide, which is strongly modulated by the oxidation state of the cysteines. This gives a plausible role for this biochemistry in controlling nitric oxide homeostasis. Mutations to control specific pr

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Alimullah, Mirza, Nishad Anjum, Md Junaeid Rahman та ін. "Identification of Polyphenols and Evaluation of Antioxidant and α-Amylase Inhibitory Activity of Wheat Bran Extracts". Journal of Biosciences and Experimental Pharmacology 1, № 1 (2023): 91–114. https://doi.org/10.62624/jbep00.0006.

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The aim of this study was to evaluate the bioactive compounds identification and determine the potential antioxidant and alpha(α)-amylase inhibitory activities of Wheat Bran (WB) extract. Phytochemical analysis was done by high performance liquid chromatography (HPLC) and gas chromatography (GC) in ethanol and n-hexane extract. Antioxidant potential was determined by nitric oxide scavenging and DPPH free radical scavenging assays. HPLC analysis showed the presence of dihydroxybenzoic acid, catechin hydrate, (-) epicatechin, caffeic acid, rutin hydrate, p-coumaric acid, trans-ferulic acid, rosm

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Dhanasezhian, Aridass, Seetharaman Srivani, and Marimuthu Ragavan Rameshkumar. "NITRIC OXIDE PRODUCTION AND ANTIOXIDANT ACTIVITY OF DRIED FRUIT EXTRACTS OF TERMINALIA CHEBULA." Asian Journal of Pharmaceutical and Clinical Research 11, no. 5 (2018): 370. http://dx.doi.org/10.22159/ajpcr.2018.v11i5.24316.

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Objective: The dried ripe fruits of Terminalia chebula have traditionally been used to treat various ailments as it has a wide spectrum of pharmacological activities. Hence, in the present study, we aimed to explore the antioxidant activity, nitric oxide production, cytotoxicity, and phytocompounds present in the aqueous and methanol extract of T. chebula. Methods: The dry fruits of T. chebula were extracted using water and methanol, and the extracts were concentrated by lyophilization method. Phytochemical analysis was done by gas chromatography and mass spectrometry and Fourier-transform inf

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Elufioye, Taiwo O., Cynthia C. Unachukwu, and Adebola O. Oyedeji. "Anticholinesterase and Antioxidant Activities of Spilanthes filicaulis Whole Plant Extracts for the Management of Alzheimer’s Disease." Current Enzyme Inhibition 15, no. 2 (2019): 103–13. http://dx.doi.org/10.2174/1573408015666190730113405.

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Background: Spilanthes filicaulis is a tropical herb implicated as a memory enhancer in ethnomedicine. Objective: The study investigated acetyl/butyryl cholinesterase inhibitory and antioxidant activities of different extracts of S. filicaulis whole plant and correlated them to its phytochemical constituents. Methods: The powdered whole plant was successively extracted with n-hexane, ethyl acetate and methanol. Acetyl cholinesterase (AChE) and Butyryl cholinesterase (BuChE) inhibitory activity were evaluated by Ellman colorimetry assay. Antioxidant activity was tested using 1, 1-diphenyl-2-pic

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CHENTOUF, Aouatif. "Antioxidant Activity of Food Protein: Yellow Pea Protein Isolate NUTRALYS® S85F in a cell free Environment." Nutrition and Food Processing 4, no. 8 (2021): 01–05. http://dx.doi.org/10.31579/2637-8914/075.

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In recent years, the demand for “all natural” products is increasing because of the increasing limitations on the use of synthetic antioxidants and enhanced public awareness of health issues. Many natural food components like oils and oilseeds, proteins and protein hydrolysates, fruits and vegetables, oat and rice bran, spices, herbs and tea have antioxidant properties. Natural antioxidants from these food components provide oxidative stability to the food product. The antioxidant activity of proteins is mainly due to interactions between their ability to inactivate reactive oxygen species, ch

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Tran, Anh Thi, Binh Thanh Nguyen, Hoai Thi Cam Ho, Huong Dang Thien Bui, and Mai Thi Thanh Nguyen. "ANTIOXIDATIVE ACTIVITIES AND CHEMICAL CONSTITUENTS OF THE ETHYL ACETATE EXTRACT FROM JASMINUM UNDULATUM KER-GAWL." Science and Technology Development Journal 14, no. 2 (2011): 50–57. http://dx.doi.org/10.32508/stdj.v14i2.1943.

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From the total crude ethanol extract of Jasminum undulatum Ker Gawl.’s leaves and stems, five fractionss were obtained by partitioning with petroleum ether, chloroform, ethyl acetate and n-butanol solvents. These five fractions were investigated for antioxidative activity using the DPPH radical scavenging and nitric oxide-inhibitory assay. All the fractions showed antioxidative activity except the petroleum ether fraction. Among the fractionss, the ethyl acetate fraction was the most potent fraction in both assays with the SC50 values of 5.30 μg/ml and 80.90 μg/ml, respectively. Further invest

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Li, Hui, Zhengxuan Wang, Mingcai Liang, Liang Cai, and Lin Yang. "Methionine Augments Antioxidant Activity of Rice Protein during Gastrointestinal Digestion." International Journal of Molecular Sciences 20, no. 4 (2019): 868. http://dx.doi.org/10.3390/ijms20040868.

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To elucidate the influence of methionine, which is an essential sulfur-containing amino acid, on the antioxidant activity of rice protein (RP), methionine was added to RP (RM). The addition of methionine to RM0.5, RM1.0, RM1.5, RM2.0, and RM2.5 was 0.5-, 1.0-, 1.5-, 2.0-, and 2.5-fold of methionine of RP, respectively. Using the in vitro digestive system, the antioxidant capacities of scavenging free radicals (superoxide; nitric oxide; 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt, ABTS), chelating metal (iron), and reducing power were investigated in the hydrolysates

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Choi, Yun-Hyeok, Jae Yeon Lee, Ji Eun Lee, et al. "Skin-Related Properties and Constituents from the Aerial Parts Extract of Persicaria senticosa." Oxidative Medicine and Cellular Longevity 2020 (December 19, 2020): 1–9. http://dx.doi.org/10.1155/2020/6627752.

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In the course of screening for cosmetic ingredients by measuring antioxidant and antiwrinkle and whitening and anti-inflammatory activities, skin-related activity was tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, 2,2 ′ -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging, elastase inhibition, tyrosinase inhibition, and nitric oxide assay. Several Polygonaseae extracts were found to show potent activity. The results showed that the Persicaria senticosa methanolic extract has the 1,1diphenyl-2picrylhydrazyl (DPPH) and ABTS radical scavenging acti

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Egbuna, Chukwuebuka, Kingsley C. Patrick-Iwuanyanwu, Eugene N. Onyeike, et al. "Mineral Profiles and Antioxidant Potentials of Polyherbal Formulation and Soursop Leaf Extracts: A Comparative Analysis." IPS Intelligentsia Multidisciplinary Journal 4, no. 1 (2025): 18–26. https://doi.org/10.54117/iimj.v4i1.8.

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This study investigated and compared the trace mineral profiles and antioxidant capacities of Polyherbal Ethanolic Extract (PHEE) and Soursop Leaf Ethanolic Extract (SLEE). Trace elements, including copper (Cu), zinc (Zn), manganese (Mn), iron (Fe), and selenium (Se), were quantified using Atomic Absorption Spectrophotometry. Antioxidant properties were assessed using DPPH, FRAP, Total Antioxidant Capacity (TAC), hydroxyl radical, and nitric oxide scavenging assays. Mineral analysis revealed higher concentrations of Cu, Mn, Fe, and Se in PHEE, while Zn was more abundant in SLEE. Both extracts

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Ilechukwu, C. C., A. C. Nwaka, J. C. Ifemeje, C. O. Ezenwelu, and J. N. Ilechukwu. "In Vitro Antioxidant and Free Radical Scavenging Activities of Pleurotus tuber-regium." IPS Journal of Natural Products 1, no. 1 (2025): 19–25. https://doi.org/10.54117/ijnp.v1i1.35.

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This study evaluated the in vitro antioxidant potential of the methanol extract of Pleurotus tuber-regium (PT) using a range of established spectrophotometric assays. These included ferric reducing antioxidant power (FRAP), nitric oxide scavenging activity, ABTS radical scavenging activity, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, metal ion chelating activity, and hydrogen peroxide scavenging activity. The results revealed that the extract exhibited concentration-dependent antioxidant activities across all assays. Although the scavenging effects of the extract were con

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Timothy, Odaro, and G. C. Ugwu. "ANTIOXIDANT ACTIVITIES OF ETHANOL LEAF EXTRACTS OF PSIDIUM GUAJAVA L., TERMINALIA CATTAPA L. AND THEIR COMBINED FORMULATION." FUDMA JOURNAL OF SCIENCES 6, no. 3 (2022): 248–53. http://dx.doi.org/10.33003/fjs-2022-0603-986.

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Free radicals in the body are the cause of many chronic and debilitating conditions in humans by acting as oxidants in the body. This research was aimed at assessing the antioxidant potential of the leaf extracts of Psidium guajava, Terminalia catappa and a combination of both. The leaves of both plants were independently extracted with ethanol. Equal portions of the extracts of both species were also combined to obtain a formulation of ratio 1:1. The extracts were subjected to in vitro assays including DPPH (2, 2-Diphenyl-1-picrylhydrazyl) and nitric oxide scavenging activities, while in vivo

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Magtoof, Mahmood S., and Noor R. Ali. "Experimental Antioxidant Activities of Synthetic 3,4-Dihydropyrimidine Derivatives." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1641–43. http://dx.doi.org/10.25258/ijddt.14.3.55.

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The synthesized of five new pyrimidine derivatives was prepared from the condensation in one pot reaction of ethyl acetoacetate, substituted aromatic aldehydes, urea, and FeCL3.6H2O, with 5 to 10 drops of hydrochloride acid as catalyst in reflexing ethanol. The yield of the product was found to be in the range of 55 to 90%. The antioxidant efficiency of synthesized compounds was estimated by using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method, hydroxyl method, nitric oxide method, and superoxide radical scavenging assay method. The compounds 6a, 6e, and 6c demonstrated considerable radical

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Priyanka Pokhriyal, Abha Shukla, and Rishi Kumar Shukla. "Antioxidant potentials of successive green solvent extracts from the unexplored Ficus subincisa." JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH 3, no. 1 (2021): 25–32. http://dx.doi.org/10.46947/joaasr312021115.

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Ficus subincisa Buch-Ham.Ex Sm. is considered an endemic medicinal plant. The current researchbased on the antioxidant potential of four different green solvent extracts obtained by the successive solventextraction method from the unexplored F.subincisa leaves was evaluated. Various in vitro assays wereperformed to achieve the aim and variation in scavenging potential of the four green extracts, showed thehighest total phenolic content (TPC), Total flavonoid content (TFC), and free radical scavenging potentialagainst DPPH, ABTS, FRAP Phosphomolybdate, and nitric oxide radical scavenging assay

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Mapunda, Pensia E., Cosmas Mligo, and Herbert V. M. Lyaruu. "EVALUATION OF FREE RADICAL SCAVENGING ABILITY AND ANTIRADICAL ACTIVITIES OF XIMENIA CAFFRA FRUIT EXTRACTS AT DIFFERENT RIPENING STAGES." International Journal of Pharmacy and Pharmaceutical Sciences 11, no. 1 (2019): 55. http://dx.doi.org/10.22159/ijpps.2019v11i1.29065.

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Methods: Using standard procedures, Ximenia caffra fruit extracts were determined for ferrous ions chelating ability, nitric oxide and hydroxyl radical scavenging ability. Antiradical activities were assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) in which the fruit extracts were evaluated for the number of antiradical units (AU515), the number of antiradical units per 1 mg of extracts (EAU515) and the total number of antiradical units per 1g of raw fruits (TAU515).Results: The fruit extracts exhibited significant higher ferrous ion chelating and free radical scavenging capacity compared t

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Nallathamby, Neeranjini, Lee Guan Serm, Jegadeesh Raman, et al. "Identification and in vitro Evaluation of Lipids from Sclerotia of Lignosus rhinocerotis for Antioxidant and Anti-neuroinflammatory Activities." Natural Product Communications 11, no. 10 (2016): 1934578X1601101. http://dx.doi.org/10.1177/1934578x1601101016.

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Lignosus rhinocerotis (Cooke) Ryvarden (Tiger milk mushroom) is traditionally used to treat inflammation triggered symptoms and illnesses such as cough, fever and asthma. The present study evaluated the in vitro antioxidant, cytotoxic and anti-neuroinflammatory activities of the extract and fractions of sclerotia powder of L. rhinocerotis on brain microglial (BV2) cells. The ethyl acetate fraction had a total phenolic content of 0.30 ± 0.11 mg GAE/g. This fraction had ferric reducing capacity of 61.8 ± 1.8 mg FSE/g, ABTS•+ scavenging activity of 36.8 ± 1.8 mg TE/g and DPPH free radical scaveng

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Sarwar, Shammy, Asif Hasan Malik, Muhammad Ashikur Rahman, Md Zakiur Rahman, and Md Sohel Rana. "Antioxidant, cytotoxic and analgesic activities of the methanolic fruit extract of Terminalia chebula Retz." International Current Pharmaceutical Journal 3, no. 1 (2013): 219–22. http://dx.doi.org/10.3329/icpj.v3i1.17296.

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The present study was aimed to investigate antioxidant, analgesic and cytotoxic activity of the methanolic extract of Terminalia chebula Retz. fruits. Antioxidant potential of the extract was evaluated by using nitric oxide scavenging assay, reducing power and total antioxidant capacity. The extract showed significant activities in all antioxidant assays compared to ascorbic acid in a dose dependent mode. In nitric oxide scavenging assay, the IC50 value of the extract was found to be 51.3 µg/mL while the IC50 value of ascorbic acid was 77.4 µg/mL. In addition to strong reducing power, total an

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Chang, Tien-Ning, Guan-Jhong Huang, Yu-Lin Ho, Shyh-Shyun Huang, Heng-Yuan Chang, and Yuan-Shiun Chang. "Antioxidant and Antiproliferative Activities of Crossostephium chinensis (L.) Makino." American Journal of Chinese Medicine 37, no. 04 (2009): 797–814. http://dx.doi.org/10.1142/s0192415x09007259.

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Crossostephium chinensis (L.) (CC) Makino is a common traditional Chinese medicinal plant used to dehumidify and cure rheumatism and arthralgia. The water and methanol extracts of C. chinensis (CCW and CCM) were evaluated for their antioxidant and antiproliferative activities. The antioxidant activities of CC were evaluated by using ABTS radical scavenging, DPPH radical scavenging, nitric oxide scavenging and superoxide scavenging methods. Iron chelating activity, lipid peroxidation, total polyphenol contents, total flavonoid contents and total flavonol contents were also detected. In all the

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Kırmızıbekmez, Hasan, Carla Bassarello, Sonia Piacente, et al. "Phenolic Compounds from Hypericum Calycinum and Their Antioxidant Activity." Natural Product Communications 4, no. 4 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400418.

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From the MeOH extract of Hypericum calycinum, two caffeoylquinic acid derivatives, butyl chlorogenate (1), and chlorogenic acid (2), seven flavonoids, quercetin (3), quercitrin (4), hyperoside (5), isoquercitrin (6), miquelianin (7), rutin (8) and I3, II8-biapigenin (9) and two flavanols, (+)-catechin (10) and (-)-epicatechin (11) were isolated. Identification of the isolates was carried out by spectroscopic analysis including 1D and 2D NMR experiments as well as mass spectrometry. Free radical scavenging activities of the isolated compounds were determined in in-vitro 1,1-diphenyl-2-picrylhyd

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Karuppusamy, Subbiah, and Gurunathan Muthuraja. "Radical Scavenging Activities of Heracleum aquilegifolium Wight (Apiaceae) Fruit Oils in vitro." Zeitschrift für Naturforschung C 65, no. 11-12 (2010): 653–59. http://dx.doi.org/10.1515/znc-2010-11-1204.

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The fruits of Heracleum aquilegifolium Wight (Apiaceae) were collected from Western Ghats of the Indian Peninsula. The essential oils were extracted by hydrodistillation. The chemical composition of the essential oils was analysed by gas chromatography and gas chromatography-mass spectrometry (GC-MS). β -Pinene (22.3%), 1,8-cineole (20.3%), and β-phellandrene (12.4%) were the main components of H. aquilegifolium fruit oils. The antioxidant properties of essential oils of H. aquilegifolium were examined by different procedures namely reducing power ability, 1,1-diphenyl-2-picrylhydrazyl (DPPH)

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Da, Qingyue, Jin Shao, Pengpeng Zhang, Jie Zhang, Huiping Ma, and Linlin Jing. "The design, synthesis, antioxidant, and antihypoxia activities of two new hydroxydaidzein derivatives." Journal of Chemical Research 46, no. 5 (2022): 174751982211315. http://dx.doi.org/10.1177/17475198221131528.

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7,8,3’,4’,5’-Pentahydroxyisoflavone (8,3’,5’-trihydroxydaidzein) and 6,7,8,3’,4’,5’-hexahydroxyisoflavone (6,8,3’,5’-tetrahydroxydaidzein) are synthesized via a simple and effective method using commercially available daidzein as a raw material. Their structures are confirmed using spectroscopic analyses (infrared, nuclear magnetic resonance, and mass spectrometry), and their purities are determined by high-performance liquid chromatography. The antioxidant capacities are investigated by utilizing 1,1-diphenyl-2-picryl-hydrazyl radical scavenging, superoxide radical scavenging, nitric oxide ra

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Liao, Jung-Chun, Jeng-Shyan Deng, Chuan-Sung Chiu, et al. "Chemical Compositions, Anti-Inflammatory, Antiproliferative and Radical-Scavenging Activities of Actinidia callosa var. ephippioides." American Journal of Chinese Medicine 40, no. 05 (2012): 1047–62. http://dx.doi.org/10.1142/s0192415x12500772.

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Oxidative stress and inflammation are related to several chronic diseases including cancer. Actinidia callosa var. ephippioides (ACE) is a special folk medicinal plant from Taiwan. The aim of this study is to evaluate the antioxidant, anti-inflammatory, and antiproliferative activities of the methanol extract and fractions from the stem of ACE. Trolox Equivalent Antioxidant Capacity (TEAC), 1,1-Diphenyl-2-picrylhydrazyl (DPPH) scavenging activity, total phenolic content, flavonoid content, inhibition on nitric oxide (NO) productions by LPS-induced RAW264.7 cell, and on lung cancer cell prolife

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M. Olabinr, B., O. O. Odedire, M. T Olaleye, A. S. Adekunl, L. O. Ehigie, and P. F. Olabinr. "In vitro Evaluation of Hydroxyl and Nitric Oxide Radical Scavenging Activities of Artemether." Research Journal of Biological Sciences 5, no. 1 (2010): 102–5. http://dx.doi.org/10.3923/rjbsci.2010.102.105.

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Wang, Jue, Tiejie Wang, Pu Xie, Guo Yin, and Xiaofan Li. "New phenanthrene derivatives with nitric oxide inhibitory and radical-scavenging activities fromPholidota imbricataHook." Natural Product Research 28, no. 4 (2013): 251–56. http://dx.doi.org/10.1080/14786419.2013.847437.

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Ebulue, M. M. "Bioactive Compounds and Antioxidant Activity of Ethanol Leaf Extract of Eucalyptus Tereticornis." ASEAN Journal of Science and Engineering 3, no. 1 (2022): 69–78. http://dx.doi.org/10.17509/ajse.v3i1.45017.

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This study evaluated the bioactive compounds present in the ethanol leaf extract of Eucalyptus tereticornis as well as its antioxidant potential using standard biochemical methods. The leaf extract contains rich number of bioactive compounds (Phenol 109.41± 0.10GAE/g, Flavonoids 33.10± 0.01mgCE/g, Beta-carotene 3.16± 0.00mg/g and Lycopene 0.32± 0.00mg/g). The antioxidant potentials were evaluated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical, iron-reducing power, inhibition of lipid peroxidation, and nitric oxide scavenging antioxidant systems. The antioxidant activities of the plant ext

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Tapas, Pramanik, and Kumar Sur Tapas. "Presence of antioxidants and nitric-oxide precursors in Mimosa pudica extract." GSC Advanced Research and Reviews 7, no. 3 (2021): 104–8. https://doi.org/10.5281/zenodo.5074689.

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Blood pressure lowering effect of <em>Mimosa pudica</em> induced by dieresis was reported earlier. As a diuretic it enhances urine outflow, decreases plasma volume, venous return; and thereby, reduce blood pressure. Besides the diuretic agent, some other blood pressure lowering substance may also be present in <em>Mimosa pudica</em><em>. </em>Present study was undertaken to reveal the presence of antioxidants and nitrite in <em>Mimosa pudica</em> extract, which may help to reduce blood pressure. Methanolic extract of <em>Mimosa pudica</em> (using 80% met

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Anzam, Zian, and Dr M. Shenbagam Madhavan. "Antioxidant and Antibacterial Activity of Cinnamaldehyde Derivative." International Journal for Research in Applied Science and Engineering Technology 10, no. 11 (2022): 1478–85. http://dx.doi.org/10.22214/ijraset.2022.47606.

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Abstract: This study reports the antibacterial and antioxidant properties of cinnamaldehyde derivatives. DPPH, Superoxide Anion Radical, Hydroxy Radical, and Nitric Oxide Radical Scavenging Activities were used to assess the test compound's antioxidant capacity. The well diffusion method was used to examine the antibacterial efficiency against both Gram positive and Gram-negative microorganisms. Both Gram positive and Gram-negative bacterial strains responded favourably to the antibacterial effects of cinnamaldehyde derivatives. The study revealed the test substance possesses strong antibacter

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Meechai, Imron, Rokeeyah Suha, Nurihan Daleng, Isma-ae Chelong, and Acharee Suksuwan. "Synergistic Effect of Pericarp of Mangosteen and Propolis from Stingless Bee Extracts on Nitric Oxide Scavenging Activity." Journal of Tropical Pharmacy and Chemistry 7, no. 1 (2023): 10–15. http://dx.doi.org/10.25026/jtpc.v7i1.458.

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The aim of this research is to study the synergistic effect on the nitric oxide scavenging activity of mangosteen pericarp and the stingless bee (Tetragonula laviceps) propolis extracts and their phytochemical constituents. The propolis and mangosteen pericarp were extracted by reflux method with ethanol. TPC and TFC of propolis extract were 123.73±2.80 mg GAE/g extract and 70.65±11.21 mg QE/g extract, respectively, and mangosteen pericarp extract was 387.93±15.10 mg GAE/g extract and 87.00±5.06 mg QE/g extract, respectively. The ESI-LC-MS data displayed that both extracts have a variety of ph

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Akhter, Parveen, Uzma Ashiq, Rifat A. Jamal, et al. "Chemistry, Alpha-glucosidase and Radical Scavenging Properties of Uranyl(VI) Hydrazide Complexes." Medicinal Chemistry 15, no. 8 (2019): 923–36. http://dx.doi.org/10.2174/1573406415666190213101044.

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Background: Antioxidant, anti-inflammatory, antiviral and antitumoral activities among others are essential characteristics in the development of novel therapeutic compounds. Acid hydrazides can form complexation with certain metal ions that positively enhance these biological characteristics. Objective: Five new complexes of uranium with hydrazide ligands were synthesized at room temperature. Methods: Methods: The characterization was done by spectroscopic methods (ESI-Mass, IR, 1H-NMR, 13CNMR), CHN analysis and conductivity measurements. Metal complexes along with their respective ligands we

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Khan, Kousik Ahmed, Manik Zahan, Fatema Zohura Talukder, et al. "Alternanthera bicolor Produces Hypoglycemic Effect in Alloxan-Induced Diabetic Mice through its Antioxidant Activity." Dhaka University Journal of Pharmaceutical Sciences 18, no. 1 (2019): 49–60. http://dx.doi.org/10.3329/dujps.v18i1.41431.

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The current investigation was carried out to evaluate the antioxidant properties of ethanolic extract of Alternanthera bicolor and to assess the potential hypoglycemic effect of the extract in alloxan-induced diabetic mice. HPLC-DAD method was used to determine polyphenolic compounds present in the extract. Different in vitro assays (i.e. DPPH radical scavenging activity test, reducing power test, NO radical inhibition assay and scavenging of hydrogen peroxide) were used to determine the antioxidant potential of the plant. Antidiabetic activity was evaluated in alloxan-induced diabetic mice by

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Elufioye, Taiwo O., Chidimma G. Chinaka, and Adebola O. Oyedeji. "Antioxidant and Anticholinesterase Activities of Macrosphyra Longistyla (DC) Hiern Relevant in the Management of Alzheimer’s Disease." Antioxidants 8, no. 9 (2019): 400. http://dx.doi.org/10.3390/antiox8090400.

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Macrosphyra longistyla has been used in many traditional systems of medicine for its anti-hemorrhagic, antidiabetic, anti-ulcer, and anti-diarrhea properties. The acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitions of the crude methanol extracts and its various partitioned fractions were determined by a modified method of Ellman. An evaluation of the antioxidant activity was carried out using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging, ferric reducing power, and nitric oxide scavenging assays. The total flavonoids were estimated based on the aluminum chlorid

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Clark, Daniel, Jörg Durner, Duroy A. Navarre, and Daniel F. Klessig. "Nitric Oxide Inhibition of Tobacco Catalase and Ascorbate Peroxidase." Molecular Plant-Microbe Interactions® 13, no. 12 (2000): 1380–84. http://dx.doi.org/10.1094/mpmi.2000.13.12.1380.

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We used a variety of nitric oxide (NO) donors to demonstrate that NO inhibits the activities of tobacco catalase and ascorbate peroxidase (APX). This inhibition appears to be reversible because removal of the NO donor led to a significant recovery of enzymatic activity. In contrast, APX and catalase were irreversibly inhibited by peroxynitrite. The ability of NO and peroxynitrite to inhibit the two major H2O2-scavenging enzymes in plant cells suggests that NO may participate in redox signaling during the activation of defense responses following pathogen attack.

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