Academic literature on the topic 'Nitrogen Heterocyclest'

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Journal articles on the topic "Nitrogen Heterocyclest"

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Rusu, Aura, Ioana-Maria Moga, Livia Uncu, and Gabriel Hancu. "The Role of Five-Membered Heterocycles in the Molecular Structure of Antibacterial Drugs Used in Therapy." Pharmaceutics 15, no. 11 (2023): 2554. http://dx.doi.org/10.3390/pharmaceutics15112554.

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Five-membered heterocycles are essential structural components in various antibacterial drugs; the physicochemical properties of a five-membered heterocycle can play a crucial role in determining the biological activity of an antibacterial drug. These properties can affect the drug’s activity spectrum, potency, and pharmacokinetic and toxicological properties. Using scientific databases, we identified and discussed the antibacterials used in therapy, containing five-membered heterocycles in their molecular structure. The identified five-membered heterocycles used in antibacterial design contai
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Xia, Xiao-Feng, та Yan-Ning Niu. "Recent developments in the synthesis of nitrogen-containing heterocycles from β-aminovinyl esters/ketones as CC–N donors". Organic & Biomolecular Chemistry 20, № 2 (2022): 282–95. http://dx.doi.org/10.1039/d1ob01998h.

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Zhu, Yannan, and You Huang. "Organocatalyzed [3+3] Annulations for the Construction of Heterocycles." Synthesis 52, no. 08 (2020): 1181–202. http://dx.doi.org/10.1055/s-0039-1690810.

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Six-membered heterocyclic systems are widely distributed in many natural products and pharmaceuticals, and the construction of highly functionalized six-membered heterocyclic compounds is an important topic in modern organic synthesis. Organocatalyzed [3+3] annulations represents an important method for assembling a substantial variety of six-membered cycles that contain one or more heteroatoms. This review describes the development of organocatalyzed [3+3] annulations for the synthesis of six-membered heterocycles, including organocatalysis using secondary amines, tertiary amines, phosphines,
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JAG, MOHAN, VERMA PRATIMA, and KUMAR VINEET. "Bridgehead Nitrogen Heterocycles: Facile Synthesis and Antimicrobial Activity of Thiazolo[ 3,2,b ]-s-tetrazines and Pyrazolo[ 3',4':4,5] thiazoIo[3,2-b ]-s-tetrazines." Journal of Indian Chemical Society Vol. 69, Oct 1992 (1992): 693–96. https://doi.org/10.5281/zenodo.6023015.

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Department of Chemistry, Maharshi Dayananda University, Rohtak-124 001 <em>Manuscript received 19 September 1991, revised 30 June 1992, accepted 16 July 1992</em> Bridgehead Nitrogen Heterocycles: Facile Synthesis and Antimicrobial Activity of Thiazolo[ 3,2,b ]-s-tetrazines and Pyrazolo[ 3&#39;,4&#39;:4,5] thiazoIo[3,2-b ]-s-tetrazines
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Pravinsing, S. Girase1 Bhikan J. Khairnar1 &. Bhata R. Chaudhari1 *2. "RECENT ADVANCES IN SYNTHESIS OF 2H-INDAZOLE FROM 2-SUBSTITUTED BENZALDEHYDE: A REVIEW." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES 6, no. 6 (2019): 178–91. https://doi.org/10.5281/zenodo.3262348.

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Several compounds has more than one nitrogen contained bicyclic heterocycles were important structural motifs found in numerous natural products and bioactive molecules. In recent years, the synthesis of bicyclic compounds possessing imidazole heterocycle as central core has been the focus of great interest. They are associated with diversified biological activities
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Yang, Ke, Zhi Li, Qingyue Hu, et al. "Recent Strategies in Nickel-Catalyzed C–H Bond Functionalization for Nitrogen-Containing Heterocycles." Catalysts 12, no. 10 (2022): 1163. http://dx.doi.org/10.3390/catal12101163.

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N-heterocycles are ubiquitous in natural products, pharmaceuticals, organic materials, and numerous functional molecules. Among the current synthetic approaches, transition metal-catalyzed C–H functionalization has gained considerable attention in recent years due to its advantages of simplicity, high atomic economy, and the ready availability of starting materials. In the field of N-heterocycle synthesis via C–H functionalization, nickel has been recognized as one of the most important catalysts. In this review, we will introduce nickel-catalyzed intramolecular and intermolecular pathways for
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Arisawa, Mitsuhiro, Shohei Ohno, Makoto Miyoshi та Kenichi Murai. "Non-Directed β- or γ-C(sp3)–H Functionalization of Saturated Nitrogen-Containing Heterocycles". Synthesis 53, № 17 (2021): 2947–60. http://dx.doi.org/10.1055/a-1483-4575.

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AbstractReactions that take place via C–H functionalization are valuable tools in organic synthesis because they can be used for the synthesis of target compounds and for the late-stage functionalization of bioactive compounds. Among these, non-directed C(sp3)–H functionalization reactions of saturated nitrogen-containing heterocycles have been developed in recent years. However, most of these lead to functionalization at the α-position relative to the heteroatom, and reactions at the β- or γ-positions are limited since these bonds are stronger and less electron-rich. Hence, in this review, we
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Trofimov, Boris A., and Anastasiya G. Mal’kina. "Cyanoacetylenic Alcohols: Molecules of Interstellar Relevance in the Synthesis of Essential Heterocycles, Amino Acids, Nucleobases and Nucleosides." Synthesis 53, no. 16 (2021): 2740–66. http://dx.doi.org/10.1055/a-1493-6840.

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AbstractCyanoacetylenic alcohols, R1R2C(OH)C≡C–CN, the closest derivatives of cyanoacetylene, an abundant interstellar molecule, are now becoming important compounds in the area of modern organic synthesis that tends to mimic Nature. The presence of highly reactive C≡C and C≡N bonds in close proximity to a hydroxy group endows cyanoacetylenic alcohols with a chemical trinity of mutually influencing functions, leading to a myriad number of chemical transformations. All reactions of cyanoacetylenic alcohols parallel modern organic synthesis, whilst being biomimetic. To react, they do not need tr
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Rusu, Aura, Octavia-Laura Oancea, Corneliu Tanase, and Livia Uncu. "Unlocking the Potential of Pyrrole: Recent Advances in New Pyrrole-Containing Compounds with Antibacterial Potential." International Journal of Molecular Sciences 25, no. 23 (2024): 12873. https://doi.org/10.3390/ijms252312873.

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Nitrogen heterocycles are valuable structural elements in the molecules of antibacterial drugs approved and used to treat bacterial infections. Pyrrole is a five-atom heterocycle found in many natural compounds with biological activity, including antibacterial activity. Numerous compounds are being develop based on the pyrrole heterocycle as new potential antibacterial drugs. Due to the phenomenon of antibacterial resistance, there is a continuous need to create new effective antibacterials. In the scientific literature, we have identified the most relevant studies that aim to develop new comp
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P., S. FERNANDES, and M. SONAR T. "Bridgehead Nitrogen Heterocycles. Synthesis and various Reactions of 5-(2-Morpholinoquinoxaline-3-yl)- 4-amino-3-mercapto-4H-1 ,2,4-triazole." Journal of Indian Chemical Society Vol. 65, Jan 1988 (1988): 49–50. https://doi.org/10.5281/zenodo.6024042.

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N. S. Research Laboratories, St. Xavier&#39;s College, Bomb&amp;y-4.00 001 <em>Manuscript received 27 July 1987, revised 21 September 1981, accepted 2&nbsp;December 1981</em> 4-Amino-3-mercapto-5-(2-morpholinoquinoxalin- 3-yl)- 4<em>H</em>-1,2,4-triazole (1), prepared by treating 2-morpholinoqufnoxaline-3-acid hydrazide successively with CS, -KOH and NH<sub>2&nbsp;</sub>NH<sub>2</sub>, gives the nitrogen bridge head fused heterocycles 2, 3, 4 and 6 on reacting with CS<sub>2</sub>&nbsp;RCOOH, PhCONCS and PhCOCH<sub>2</sub>Br, respectively.
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Dissertations / Theses on the topic "Nitrogen Heterocyclest"

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Hemmings, Philippa Rachel. "Nitrogen heterocycles from sugars." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314823.

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Slater, Jonathan. "Cyclometallated nitrogen heterocycles - metallomesogens." Thesis, University of Warwick, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269196.

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Treacy, Alan Bernard. "Nitrogen heterocycles in asymmetric synthesis." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361310.

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Jones, A. D. "Novel syntheses of nitrogen heterocycles." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388287.

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McGuigan, H. "Synthetic studies on nitrogen heterocycles." Thesis, University of Glasgow, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375469.

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Burnett, Duane Arthur. "Synthesis of nitrogen containing heterocycles /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487264603219377.

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Qaddo, Akram. "Enantiospecific nitrogen heterocycle synthesis." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/15791/.

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Austin, Carolyn A. "Diversity-Based Synthesis of Nitrogen Heterocycles." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.484942.

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Brief investigations were carried out towards the synthesis of 2,4-disubstituted quinolines and 2,6-disubstituted piperidines using titanium alkylidene chemistry, but these were unsuccessful. A route towards the diversity based stereoselective synthesis of 2-substituted azepane derivatives was explored via titanium alkylidene chemistry. Thioacetals i were reacted with low valent titanium(II) species ii to produce titanium(IV) alkylidenes that were reacted with resin-bound esters iii. Cleavage of the resulting enol ethers led to a small library of amino ketones iv, but reductive amination to gi
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Jones, Matthew Lloyd. "Radical rearrangements of nitrogen-containing heterocycles." Thesis, University of Oxford, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289342.

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Anwar, Muhammad. "Synthesis of highly functionalised nitrogen heterocycles." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441057.

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Books on the topic "Nitrogen Heterocyclest"

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Wongtap, Hathaichanuk. A radical approach to nitrogen heterocycles. typescript, 1999.

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Parshikov, Igor A. Microbial Transformation of Nitrogen Containing Heterocycles. Primedia E-launch LLC, 2016.

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El Ashry, El Sayed H., and Ahmed El Nemr, eds. Synthesis of Naturally Occurring Nitrogen Heterocycles from Carbohydrates. Blackwell Publishing Ltd, 2005. http://dx.doi.org/10.1002/9780470988619.

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1962-, El-Nemr Ahmed, ed. Synthesis of naturally occurring nitrogen heterocycles from carbohydrates. Blackwell Pub., 2005.

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Filik, Robert Paul. Synthesis of nitrogen containing heterocycles via radical cyclisation. typescript, 2000.

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Hatton, Kevin Brian. Studies on the synthesis of nitrogen and oxygen heterocycles. University of East Anglia, 1986.

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Vicario, Jose L., Dolores Badia, and Luisa Carrillo. New methods for the asymmetric synthesis of nitrogen heterocycles 2005. Research Signpost, 2005.

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Rees, Anthony John. The synthesis and reactions of some fluorinated nitrogen-containing heterocycles. University of Birmingham, 1996.

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McWilliams, Andrew Robert. The synthesis, novel reactivity and polymerization behavior of boron- and sulfur-nitrogen-phosphorus heterocycles. National Library of Canada, 1999.

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Fowler, Frank W. Advances Nitrogen Heterocycles (Advances in Nitrogen Heterocycles). Jai Pr, 1996.

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Book chapters on the topic "Nitrogen Heterocyclest"

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Rowlands, C. C., and R. D. Farley. "15.3.2 Nitrogen containing heterocycles." In Landolt-Börnstein - Group II Molecules and Radicals. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-45824-1_40.

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Haas, Alois, Dieter Koschel, and Ulrich Niemann. "Fused Perfluorohalogenoorgano Nitrogen Heterocycles." In F Perfluorohalogenoorgano Compounds of Main Group Elements. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-07759-7_6.

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Haas, Alois, Dieter Koschel, and Ulrich Niemann. "Three-Membered Perfluorohalogenoorgano Nitrogen Heterocycles." In F Perfluorohalogenoorgano Compounds of Main Group Elements. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-07759-7_1.

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Haas, Alois, Dieter Koschel, and Ulrich Niemann. "Four-Membered Perfluorohalogenoorgano Nitrogen Heterocycles." In F Perfluorohalogenoorgano Compounds of Main Group Elements. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-07759-7_2.

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Haas, Alois, Dieter Koschel, and Ulrich Niemann. "Five-Membered Perfluorohalogenoorgano Nitrogen Heterocycles." In F Perfluorohalogenoorgano Compounds of Main Group Elements. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-07759-7_3.

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Haas, Alois, Dieter Koschel, and Ulrich Niemann. "Six-Membered Perfluorohalogenoorgano Nitrogen Heterocycles." In F Perfluorohalogenoorgano Compounds of Main Group Elements. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-07759-7_4.

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Assad, Humira, Suresh Kumar, and Ashish Kumar. "Nitrogen, Sulfur, and Nitrogen-based Heterocycles Corrosion Inhibitors." In Handbook of Heterocyclic Corrosion Inhibitors. CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-11.

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Brown, E. G. "N-Heterocycles and living systems — conclusions." In Ring Nitrogen and Key Biomolecules. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4906-8_10.

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Joule, J. A., K. Mills, and G. F. Smith. "Heterocycles containing a ring-junction nitrogen." In Heterocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_24.

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Vaquero, Juan J., and Julio Alvarez-Builla. "Heterocycles Containing a Ring-Junction Nitrogen." In Modern Heterocyclic Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527637737.ch22.

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Conference papers on the topic "Nitrogen Heterocyclest"

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Mangalagiu, Violeta, Dorina Amariucai-Mantu, Dumitrela Diaconu, Vasilichia Antoci, and Ionel Mangalagiu. "MICROWAVE AND ULTRASOUND ASSISTED SYNTHESIS AS ECOLOGICALLY FRIENDLY METHODS IN NITROGEN HETEROCYCLIC CHEMISTRY." In SGEM International Multidisciplinary Scientific GeoConference. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024v/6.2/s23.04.

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On the last few years, microwave and ultrasound irradiation has become a successful tool in modern medicinal and organic chemistry especially (but not only) because in many cases synthesis became ecologically friendly. As part of our ongoing efforts in the field of nitrogen heterocyclic derivatives, we present herein some core results obtained by our group in the field of N-alkylation and 3+2 cycloadditions reactions applied in the nitrogen heterocycles series, by using microwave and ultrasound irradiation. Comparative with conventional thermal heating, undeniable advantages of using microwave
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Tabolin, Andrey, Vladimir Motornov, Valentine Nenajdenko та Sema Ioffeа. "α-FLUORONITROALKENES IN THE SYNTHESIS OF FLUORINATED HETEROCYCLES". У Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m735.aks-2019/123-125.

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Efimova, Tatyana, Olga Ozerova, Maria Ivanova, and Tamara Novikova. "1-AMINO-2-NITROGUANIDINE IN THE SYNTHESIS OF NITROGEN HETEROCYCLES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m733.aks-2019/112-118.

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Voinkov, E., E. Ulomsky, and V. Rusinova. "STABLE NITROACETONITRILE POTASSIUM SALT IN SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m784.aks-2019/319-321.

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Gutierrez, Margarita, Yorley Duarte, Barbara Arevalo, et al. "NITROGEN HETEROCYCLES AS POTENTIAL ANTIBACTERIAL AGENTS." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a035.

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Savateev, Konstantin, Evgeny Ulomsky, and Vladimir Rusinova. "CHLORODEOXYGENATION OF NITROAZOLOPYRIMIDINES AS A PROMISING METHOD FOR SYNTHESIS OF HETEROCYCLES WITH USEFUL BIOLOGICAL ACTIVITY." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m734.aks-2019/119-122.

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Mangalagiu, Violeta, Dumitrela Diaconu, Costel Moldoveanu, et al. "Hybrid and chimeric nitrogen heterocycles with biological activity." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab01.

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Nitrogen heterocycles, especially azine and azole derivatives, are highly valuable scaffolds in medicinal chemistry, being the core components of a large variety of drugs with variously biological activity such as antiplasmodial and antimalarial, antitubercular, antibacterial, antifungal, anticancer, analgesic, antidepressant, anxiolytics, antihypertensive, anticoagulants, diuretics, etc. As a result, obtaining of such entities continues to arouse a strong interest from academia and industry. As part of our ongoing research in the area of nitrogen heterocyclic derivatives, we present herein so
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Silva, Gabriela D. da, Piero Bagnaresi, and Rodrigo L. O. R. Cunha. "Organoselenium functionalized nitrogen heterocycles: a proposition for new antimalarials." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_20131014142313.

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Карасева, И. Н., М. О. Карасев, and С. В. Курбатова. "IDENTIFICATION OF THE COMPONENTS OF COMPLEX MIXTURES OF NITROGENIC HETEROCYCLES." In Инновации и «зелёные» технологии : IV Всероссийская научно-практическая конференция. Crossref, 2024. http://dx.doi.org/10.34830/sounb-conf.2023.64.97.017.

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В статье рассмотрены вопросы, связанные с исследованием производных азотистых гетероциклов в условиях обращенно-фазового варианта высокоэффективной жидкостной хроматографии. Определены сорбционные и физико-химические характеристики некоторых производных азолов. Предложено использование спектрального подхода для групповой идентификации компонентов сложных смесей азотистых гетероциклов и корреляций между удерживанием и физико-химическими параметрами для индивидуальной идентификации. The article deals with issues related to the study of nitrogenous heterocycles derivatives under conditions of a r
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Stevanović, Nevena Lj, Mia Stanković, Tina P. Andrejević, Darko P. Ašanin, Ivana M. Stanojević, and Biljana Đ. Glišić. "DNA AND BSA INTERACTIONS OF COPPER(II) AND ZINC(II) COMPLEXES WITH ANTIFUNGAL AGENT FLUCONAZOLE." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.399s.

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Aromatic nitrogen-containing heterocycles (N-heterocycles) have attracted a considerable attention as scaffolds for compounds, which have an application in different pharmacological areas, ranging from vitamins to different antimicrobial and antitumor agents. In this respect, azoles are of special importance as potent and broad-spectrum agents used for the treatment of many invasive fungal infections. In the present study, the interaction of the clinically used antifungal drug fluconazole (fcz) and its copper(II) and zinc(II) complexes, {[CuCl2(fcz)2].5H2O}n (1) and {[ZnCl2(fcz)2]·2C2H5OH}n (2
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Reports on the topic "Nitrogen Heterocyclest"

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Lineberger, William C., and Veronica M. Bierbaum. Thermochemistry and Dynamics of Reactive Species: Nitrogen-Rich Substituted Heterocycles and Anionic Components of Ionic Liquids. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada495370.

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