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Relevant bibliographies by topics / Nuclear atypia

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Academic literature on the topic 'Nuclear atypia'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Nuclear atypia"

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Visscher, Daniel W. "Apocrine Ductal Carcinoma In Situ Involving a Sclerosing Lesion With Adenosis: Report of a Case." Archives of Pathology & Laboratory Medicine 133, no. 11 (2009): 1817–21. http://dx.doi.org/10.5858/133.11.1817.

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Abstract Apocrine metaplasia is a ubiquitous component of the mammary fibrocystic change spectrum. Although mostly associated with cysts, apocrine metaplasia can also present as a proliferative lesion, rarely with cytologic atypism. Apocrine atypia is characterized by 3-fold nuclear enlargement, multiple nucleoli, and hyperchromatism and generally arises in florid adenosis or radial sclerosing lesions. Dramatic apocrine atypia may be very difficult to distinguish from apocrine ductal carcinoma in situ. The latter is distinguished from apocrine atypia by greater extent of the lesion (&gt;0.

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Varshney, Himanshu, Manish Kumar Sharma, C. S. Mahendran, and Ranvijay Tiwari. "A case series on reactive atypia findings in cytology examination of bronchoalveolar lavage samples." Santosh University Journal of Health Sciences 10, no. 1 (2024): 130–32. http://dx.doi.org/10.4103/sujhs.sujhs_26_24.

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ABSTRACT Reactive atypia in bronchoalveolar lavage (BAL) cells reflects cellular changes frequently observed in respiratory cytology, typically resulting from injury, inflammation, or irritation rather than malignancy. This review examines the nature, causes, and diagnostic implications of reactive atypia in BAL specimens. BAL is a diagnostic procedure used to collect cells from the lower respiratory tract. Identifying atypical cells in BAL samples poses a significant challenge, as their morphology can resemble that of neoplastic processes. Characteristics of reactive atypia include nuclear en

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M, Logaswari, Mark JA Koh, and Kesavan Sittampalam. "Atypical fibrous histiocytomas and pleomorphic fibroma-type lesions in a patient with li-fraumeni syndrome." Proceedings of Singapore Healthcare 32 (January 18, 2023): 201010582311520. http://dx.doi.org/10.1177/20101058231152047.

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Atypical fibrous histiocytomas are an uncommon but benign variant of dermatofibroma where the neoplastic cells can feature cytological atypia constituted by prominent nuclear enlargement, pleomorphism and multinucleated giant cells. Though these can have a degree of atypia, they have a benign course and a failure to recognize these tumors as benign can lead to misdiagnosis and overtreatment, particularly in patients with Li-Fraumeni syndrome who are known to be predisposed to various malignancies. Here, we report a patient with atypical fibrous histiocytomas and multiple pleomorphic fibroma-ty

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Asirvatham, Jaya Ruth, Maria Monica Garcia Falcone, and Celina G. Kleer. "Atypical Apocrine Adenosis: Diagnostic Challenges and Pitfalls." Archives of Pathology & Laboratory Medicine 140, no. 10 (2016): 1045–51. http://dx.doi.org/10.5858/arpa.2016-0238-ra.

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Apocrine change in the breast is an extremely common finding. In most cases, the benign or malignant nature of the lesion is easily recognized. Apocrine adenosis is used to describe sclerosing adenosis with apocrine change. The term apocrine atypia is used when there is significant cytologic atypia in apocrine cells, characterized by a 3-fold nuclear enlargement, prominent/multiple nucleoli, and hyperchromasia. Atypical apocrine adenosis is diagnosed when apocrine adenosis and apocrine atypia are superimposed. However, there are no definite criteria to distinguish atypical apocrine adenosis fr

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Pyo, Jung-Soo, Dae Hyun Lim, Kyueng-Whan Min, Nae Yu Kim, Il Hwan Oh, and Byoung Kwan Son. "Diagnostic Assessment of Endoscopic Ultrasonography–Fine Needle Aspiration Cytology in the Pancreas: A Comparison between Liquid-Based Preparation and Conventional Smear." Medicina 60, no. 6 (2024): 930. http://dx.doi.org/10.3390/medicina60060930.

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Background and Objectives: This study aimed to elucidate the cytologic characteristics and diagnostic usefulness of endoscopic ultrasonography–fine needle aspiration cytology (EUS-FNAC) by comparing it with liquid-based preparation (LBP) and conventional smear (CS) in pancreas. Methods: The diagnostic categories (I through VII) were classified according to the World Health Organization Reporting System for Pancreaticobiliary Cytopathology. Ten cytologic features, including nuclear and additional features, were evaluated in 53 cases subjected to EUS-FNAC. Nuclear features comprised irregular nu

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Yasuda, Masatoshi. "Atypia and Surface Structure of Superficial Neoplasms of the Colon Less Than 10 mm in Diameter." Diagnostic and Therapeutic Endoscopy 2, no. 3 (1996): 135–46. http://dx.doi.org/10.1155/dte.2.135.

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Histological specimens of 30 distinct adenomas and 30 distinct carcinomas were studied by image analysis to quantify nuclear size and shape. These data were used to derive a discriminant equation, which permitted the lesions to be classified into two groups based on nuclear atypia. Next, 50 superficial type tumors of the colon (34 IIa lesions, 9 IIc + IIa lesions, and 7 IIc lesions) <10 mm in longest diameter were similarly analyzed. These lesions were classified into a high atypia index group (HAI group, 14 lesions) and a low atypia index group (LAI group, 36 lesions) by the above discrimi

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Kim, Hyunjin, Sangjoon Choi, Sung-Im Do, Sang Hwa Lee, Nara Yoon, and Hyun-Soo Kim. "Clinicopathological Characteristics of Pleomorphic High-Grade Squamous Intraepithelial Lesion of the Uterine Cervix: A Single-Institutional Series of 31 Cases." Diagnostics 10, no. 8 (2020): 595. http://dx.doi.org/10.3390/diagnostics10080595.

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We investigated the clinicopathological characteristics of 31 cases of pleomorphic high-grade squamous intraepithelial lesions (PHSIL) of the uterine cervix. We reviewed electronic medical records and all available slides to collect clinical and pathological information. PHSILs were histologically characterized by significant nuclear enlargement, marked pleomorphism, hyperchromasia, increased mitotic activity, and frequent atypical mitoses. In the majority of cases (24/31; 77.4%), this striking nuclear atypia involved both the surface epithelium and the endocervical glands. In the remaining se

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Słowińska-Klencka, Dorota, Bożena Popowicz, Dominika Kulczycka-Wojdala, et al. "Effective Use of microRNA, BRAF and Sonographic Risk Assessment in Bethesda III Thyroid Nodules Requires a Different Approach to Nodules with Features of Nuclear Atypia and Other Types of Atypia." Cancers 15, no. 17 (2023): 4287. http://dx.doi.org/10.3390/cancers15174287.

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The aim of the study was to analyze the diagnostic usefulness of the combined assessment of the ultrasound risk category of the nodule (evaluated with EU-TIRADS system), the presence of BRAF V600E mutation and the expression of selected microRNAs (miR-146b, miR-221 and miR-222) in Bethesda category III thyroid nodules, separately for cases with nuclear atypia (AUS-nuclear) and cases with other types of atypia (AUS-other). We evaluated 161 nodules (66 AUS-nuclear and 95 AUS-other) with known results of postoperative histopathological examination. The rate of cancer and the rate of PTC among can

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Bertoni, Franco, Luis Fernando Arias, Marco Alberghini, and Patrizia Bacchini. "Fibrous Dysplasia With Degenerative Atypia: A Benign Lesion Potentially Mistaken for Sarcoma." Archives of Pathology & Laboratory Medicine 128, no. 7 (2004): 794–96. http://dx.doi.org/10.5858/2004-128-794-fdwdaa.

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Abstract Fibrous dysplasia is a benign disorder of bone in which proliferating fibrous tissue replaces the bony spongiosa. Cytologic atypia is generally not considered a feature of this proliferating tissue. We present a case of fibrous dysplasia with marked atypical nuclear changes consistent with degenerative or regressive changes. A 42-year-old man presented with an osteolytic lesion of the right iliac bone. Histologic study demonstrated a fibro-osseous lesion with woven bone trabeculae and bland-looking fibrous tissue. Several areas showed atypical cells with enlarged pleomorphic nuclei an

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Travaglino, Antonio, Frediano Inzani, Angela Santoro, et al. "Endometrial Metaplastic/Reactive Changes Coexistent with Endometrial Hyperplasia and Carcinoma: A Morphological and Immunohistochemical Study." Diagnostics 12, no. 1 (2021): 63. http://dx.doi.org/10.3390/diagnostics12010063.

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The aim of this study was to assess the relationship between endometrial metaplastic/reactive changes (EMRCs) and endometrial neoplastic lesions. Twenty cases of “simple” (without architecture complexity) EMRCs coexistent with endometrial malignant/premalignant lesions, twenty cases of neoplasia-unassociated EMRCs, and eight cases of complex metaplastic lesions were assessed by immunohistochemistry. EMRCs coexisted with endometrioid carcinoma (n = 12), atypical endometrial hyperplasia (n = 3), serous carcinoma (n = 2), and clear cell carcinoma (n = 3). Neoplasia-associated EMRCs showed a mean

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Dissertations / Theses on the topic "Nuclear atypia"

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Johansson, Lotta. "Studies on the atypical orphan receptor SHP /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-071-7/.

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Bris, Céline. "Influence de la génétique mitochondriale en pathologie : apport des techniques de séquençage haut débit Deep sequencing shows that oocytes are not prone to accumulate mtDNA heteroplasmic mutations during ovarian ageing Novel NDUFS4 gene mutation in an atypical late-onset mitochondrial form of multifocal dystonia." Thesis, Angers, 2017. http://www.theses.fr/2017ANGE0093.

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Les maladies mitochondriales sont des pathologies fréquentes du métabolisme caractérisées par une forte hétérogénéité clinique et génétique, notamment par la dépendance à 2 génomes, nucléaire (ADNn) et mitochondrial (ADNmt), et le concept d’hétéroplasmie (HT). L’objectif de ce travail de thèse a été de développer une stratégie d’analyse de l’ADNmt par séquençage haut-débit (NGS), puis de l’appliquer à l’étude des maladies mitochondriales et des pathologies liées au vieillissement : glaucome à angle ouvert (GPAO) et vieillissement ovarien précoce. Après validation des performances de notre stra

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Huang, Sufang. "The role of atypical PKC in the plasticity of the circadian clock in the rat suprachiasmatic nucleus /." 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3337797.

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Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.<br>Source: Dissertation Abstracts International, Volume: 69-11, Section: B, page: 6510. Advisers: David Clayton; Martha U. Gillett. Includes bibliographical references. Available on microfilm from Pro Quest Information and Learning.

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Book chapters on the topic "Nuclear atypia"

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Shaji, Soorya, M. Sreeraj, Jestin Joy, and Alphonsa Kuriakose. "On Computer-Aided Diagnosis of Breast Cancers Using Nuclear Atypia Scoring." In Lecture Notes in Electrical Engineering. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3992-3_57.

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Varghese, Jithy, and J. S. Saleema. "Machine Learning Techniques for Automated Nuclear Atypia Detection in Histopathology Images: A Review." In Inventive Computation and Information Technologies. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-7402-1_51.

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Maksem, John A., Stanley J. Robboy, John W. Bishop, and Isabelle Meiers. "Cytoarchitecture and Nuclear Atypia as the Bases for the Cytology Risk-Stratification of Endometrial Samplings." In Endometrial Cytology with Tissue Correlations. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-89910-7_4.

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Khan, Adnan Mujahid, Korsuk Sirinukunwattana, and Nasir Rajpoot. "Geodesic Geometric Mean of Regional Covariance Descriptors as an Image-Level Descriptor for Nuclear Atypia Grading in Breast Histology Images." In Machine Learning in Medical Imaging. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10581-9_13.

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Morbelli, Silvia, and Giulia Ferrarazzo. "Case 12: Huntington’s Disease with Atypical Onset." In Clinical Nuclear Medicine in Neurology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83598-9_12.

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Cecchin, Diego, Gianni Sorarù, and Mariagiulia Anglani. "Case 37: Atypical Upper Motor Neuron Disease." In Clinical Nuclear Medicine in Neurology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83598-9_37.

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Traub-Weidinger, Tatjana, Amedeo A. Azizi, Christian Dorfer, and Julia Furtner. "Case 31: Atypical Teratoid Rhabdoid Tumor (ATRT): Identification of Altered Cerebrospinal Fluid Circulation Impacting Intrathecal Chemotherapy." In Clinical Nuclear Medicine in Neurology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83598-9_31.

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Singhal, Aditi, Kriti Kapil, Ankit Dodla, Sanjay Kumar, and Bhaskar Datta. "Nucleic Acid Based Nanoconstructs for Environmental Analysis in Atypical Contexts." In Nanotechnology for Energy and Environmental Engineering. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-33774-2_25.

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"Nuclear Atypia." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_4147.

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Basolo, Fulvio, and Clara Ugolini. "Pathology of Thyroid Cancer." In Oxford Textbook of Endocrinology and Diabetes 3e, edited by John A. H. Wass, Wiebke Arlt, and Robert K. Semple. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198870197.003.0078.

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Thyroid malignant lesions include a heterogeneous group of pathologies with different origins, different morphological aspects, and different outcomes. They can originate from follicular cells or from parafollicular C cells. Papillary and follicular thyroid carcinomas arise from follicular cell while medullary cancer develops from the C cell. Papillary cancer can show several variants with different morphological aspects. The most frequent are the classical variant with a typical papillary growth pattern and the follicular variant with an exclusive follicular growth pattern. The different vari

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Conference papers on the topic "Nuclear atypia"

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Binu Simon, Bibin, Riboy Cheriyan, and Sudha T. "Evolving Perspectives in Nuclear Atypia Scoring: From Traditional Methods to Modern Insights." In 2025 Emerging Technologies for Intelligent Systems (ETIS). IEEE, 2025. https://doi.org/10.1109/etis64005.2025.10961915.

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Rollins, B. C., S. Chawla, J. Gerst, et al. "Review of Techniques to Evaluate SCC Susceptibility of Carbon Steels Used in Construction of Hanford Nuclear Reservation Waste Tanks." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-18062.

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Abstract Stress corrosion cracking (SCC) is a documented threat to the integrity of carbon steel radioactive waste storage tanks at the Hanford Nuclear Reservation site. Presently, the slow strain rate (SSR) test is the workhorse test technique used for assessing SCC of carbon steels in nuclear waste simulants. The main advantages of the standard SSR technique are that it is relatively rapid, sensitive in detecting SCC, and relatively inexpensive. SSR test results are typically classified as “SCC” or “No SCC”, depending on the ductility parameters from the test and observations of crack featur

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Glazer, Evan S., Kimberly A. Hill, Hao (Helen) Zhang, et al. "Abstract 1362: Nuclear morphometry measures progressive atypia in the development of pancreatic carcinoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1362.

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Jafarbiglo, Sanaz Karimi, Habibollah Danyali, and Mohammad Sadegh Helfroush. "Nuclear Atypia Grading in Histopathological Images of Breast Cancer Using Convolutional Neural Networks." In 2018 4th Iranian Conference on Signal Processing and Intelligent Systems (ICSPIS). IEEE, 2018. http://dx.doi.org/10.1109/icspis.2018.8700540.

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Machado, Samira Juliana de Moraes, Marina Sonagli, Fernanda Perez Magnani Leite, Cynthia Aparecida Bueno de Toledo Osório, and Fabiana Baroni Alves Makdissi. "Pseudolactational secretory hyperplasia (pregnancy-like hyperplasia) with atypia: a case series and literature review." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2059.

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Introduction: Pseudolactational secretory hyperplasia (PLH) or pregnancy-like (pseudolactational) hyperplasia is a rare condition associated with an incidental finding in biopsies investigating benign and malignant breast lesions. These lesions affect non-pregnant women, typically between the 4th and 6th decades of life, with no described relationship to prior oncological diagnosis or previous pregnancy and lactation. Its frequency is approximately 3%, considering findings from surgical and autopsy reports. Histologically, they are lobulocentric epithelial lesions with characteristic intra- an

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H. Qasim, Ahmed. "Nuclear Apoptosis Inducing Factor 1 (NAIF1) Gene Expression In NonTumoral Human Tissues." In XI. International Scientific Congress of Pure, Applied and Technological Sciences (MINAR Congress). Rimar Academy, 2024. https://doi.org/10.47832/minarcongress11-14.

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Background: The nuclear apoptosis inducing factor1 (NAIF1) is frequently inactivated or not expressed in advanced human malignancies. Fascinatingly, no much data is available regarding the natural impression of NAIF1 expression in normal human tissue. The purpose of this work is to describe how the NAIF1 protein is expressed in normal human tissues. Materials and procedures: 50 samples of normal human tissue were examined using western blot and immunohistochemical method to determine the expression of NAIF1. Normal or inflammatory tissues without signs of cellular atypia were included as inclu

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Zhu, Xuedong, and Xi Lu. "Automatic Nuclear Atypia Scoring of Breast Cancer Pathological Images Based on Deep Residual Network and Meta-decision Tree." In 2022 7th International Conference on Control and Robotics Engineering (ICCRE). IEEE, 2022. http://dx.doi.org/10.1109/iccre55123.2022.9770238.

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Williams, PA, CE Parra-Herran, Y. Ayroud та ін. "Abstract P1-01-11: Nuclear immunohistochemical IKK-εexpression in flat epithelial atypia (FEA) of the breast: A predictor of ipsilateral ADH, in-situ or invasive malignancy?" У Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-p1-01-11.

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Savita, Pannu, and Khullar Harsha. "Two interesting cases of granulosa cell tumor: A case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685326.

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Introduction: Granulosa cell tumor (GCT) is an ovarian malignancy that arise from granulosa cells of the ovary. This tumour is a type of the sex cord-gonadal stromal tumour. GCT have good prognosis in comparison with other epithelial tumors. Methodology: Two cases of granulosa cell tumors were diagnosed in sir Ganga ram hospital, Rajendernagar, New Delhi in December 2015 and January 2016. The patient’s age, clinical manifestations, radiological and histopathological findings were evaluated. One was in perimenopausal age group and other case was in postmenopausal age group. The clinical manifes

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Savita, Pannu, and Khullar Harsha. "Two interesting cases of granulosa cell tumor: A case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685309.

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Introduction: Granulosa cell tumor (GCT) is an ovarian malignancy that arise from granulosa cells of the ovary. This tumour is a type of the sex cord-gonadal stromal tumour. GCT have good prognosis in comparison with other epithelial tumors. Methodology: Two cases of granulosa cell tumors were diagnosed in sir Ganga ram hospital, Rajender Nagar, New Delhi in December 2015 and January 2016. The patient’s age, clinical manifestations, radiological and histopathological findings were evaluated. One was in perimenopausal age group and other case was in postmenopausal age group. The clinical manife

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Reports on the topic "Nuclear atypia"

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Tran, Emily, Jasmine J. Park, Nandini N. Kulkarni, and Vinay S. Gundlapalli. Left Facial Primary Leiomyosarcoma Misdiagnosed as Atypical Fibroxanthoma and Immunochemical Markers Relevant to Diagnosis: A Case Report. Science Repository, 2024. http://dx.doi.org/10.31487/j.ajscr.2023.04.03.

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Soft tissue sarcomas are relatively rare neoplasms of mesenchymal origin that generally make up less than 2% of all adult malignant neoplasms. Atypical fibroxanthoma is a benign soft tissue tumor often confused with malignant variants of similar tumors such as leiomyosarcoma due to similar staining markers and cell morphology. We report a case of a 70-year-old caucasian male who initially presented with a 2 cm exophytic left facial lesion that was misdiagnosed as atypical fibroxanthoma upon biopsy. The patient underwent a wide local excision of the growing 11 cm mass and immediate reconstructi

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