Relevant bibliographies by topics / ONCOTHERAPEUTICS

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'ONCOTHERAPEUTICS'

Author: Grafiati
Published: 11 September 2023
Last updated: 31 July 2025

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Journal articles on the topic "ONCOTHERAPEUTICS"

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Raja, Junaid, and David C. Madoff. "Oncopharmacology in Interventional Radiology." Seminars in Interventional Radiology 39, no. 04 (2022): 411–15. http://dx.doi.org/10.1055/s-0042-1758076.

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AbstractThe broad scope of malignancies treated in interventional oncology is mirrored by the breadth of oncotherapeutics, drugs used to treat cancer. Many of these treatments are administered endovascularly, though a group of therapies can be delivered percutaneously. Perhaps the best taxonomy of oncotherapeutics is based on their biological inactivity or activity and the mechanism by which they interact with treated and targeted tissues. As the fields of interventional oncology and oncotherapeutics continue to grow and expand, this framework may provide a more organized approach in helping d
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Ladd, Joseph. "Advancements in oncotherapeutics drive positive outcomes in cancer." Pharmacy Today 23, no. 7 (2017): 24–25. http://dx.doi.org/10.1016/j.ptdy.2017.06.019.

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Dailey, Kaitlin M., JuliAnne E. Allgood, Paige R. Johnson, et al. "The next frontier of oncotherapy: accomplishing clinical translation of oncolytic bacteria through genetic engineering." Future Microbiology 16, no. 5 (2021): 341–68. http://dx.doi.org/10.2217/fmb-2020-0245.

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The development of a ‘smart’ drug capable of distinguishing tumor from host cells has been sought for centuries, but the microenvironment of solid tumors continues to confound therapeutics. Solid tumors present several challenges for current oncotherapeutics, including aberrant vascularization, hypoxia, necrosis, abnormally high pH and local immune suppression. While traditional chemotherapeutics are limited by such an environment, oncolytic microbes are drawn to it – having an innate ability to selectively infect, colonize and eradicate solid tumors. Development of an oncolytic species would
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Kansara, Samarth, Vijay Pandey, Peter E. Lobie, Gautam Sethi, Manoj Garg, and Amit Kumar Pandey. "Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer." Cells 9, no. 6 (2020): 1511. http://dx.doi.org/10.3390/cells9061511.

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Triple-negative breast cancer (TNBC) is one of the most lethal forms of breast cancer (BC), with a significant disease burden worldwide. Chemoresistance and lack of targeted therapeutics are major hindrances to effective treatments in the clinic and are crucial causes of a worse prognosis and high rate of relapse/recurrence in patients diagnosed with TNBC. In the last decade, long non-coding RNAs (lncRNAs) have been found to perform a pivotal role in most cellular functions. The aberrant functional expression of lncRNAs plays an ever-increasing role in the progression of diverse malignancies,
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Ramesh, Bandla, Krishna Madhava, Gowri Gogada Jaisatya, et al. "A propsective oncotherapeutics: Isolation, partial purification and assessment of anti-coagulant properties of Tridax procumbens from leaf extracts." Onkologia i Radioterapia 19, no. 1 (2025): 01–11. https://doi.org/10.5281/zenodo.15581591.

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Medicinal plants, mostly herbs have been widely used since ancient times for the treatment of various human diseases including cancers, with the advent of technology and extensive research relating use of herbal drugs in the health care sector has increased. The WHO reports, almost 80% of people serve through medicinal plants and their products. About 25% of active pharmaceutical drugs were derived from herbal plants. This study investigates the potential anticoagulant properties of Tridax procumbens, a medicinal plant. The study demonstrates the isolation procedure of partially purified leaf
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Raftopoulou, Christina, Fani-Marlen Roumelioti, Eleni Dragona, et al. "Karyotypic Flexibility of the Complex Cancer Genome and the Role of Polyploidization in Maintenance of Structural Integrity of Cancer Chromosomes." Cancers 12, no. 3 (2020): 591. http://dx.doi.org/10.3390/cancers12030591.

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Ongoing chromosomal instability in neoplasia (CIN) generates intratumor genomic heterogeneity and limits the efficiency of oncotherapeutics. Neoplastic human cells utilizing the alternative lengthening of telomeres (ALT)-pathway, display extensive structural and numerical CIN. To unravel patterns of genome evolution driven by oncogene-replication stress, telomere dysfunction, or genotoxic therapeutic interventions, we examined by comparative genomic hybridization five karyotypically-diverse outcomes of the ALT osteosarcoma cell line U2-OS. These results demonstrate a high tendency of the compl
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Adeniji, Emmanuel A., Fisayo A. Olotu, and Mahmoud E. S. Soliman. "Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target." Anti-Cancer Agents in Medicinal Chemistry 18, no. 11 (2019): 1540–50. http://dx.doi.org/10.2174/1871520618666180718110231.

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Background: The difficulty in druggability of K-Ras variant has presented a challenge in the treatment of cancer diseases associated with its dysfunctionality. Despite the identification of different binding sites, limited information exists in the literature about their characteristics. Therefore, identification, crossvalidation and characterization of its druggable sites would aid the design of chemical compounds that will arrest its dysfunctionality related oncogenesis. Objective: This study entails the identification, cross-validation and characterization of K-Ras G12C variant’s binding si
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Lantier, Louis, Agathe Poupee-Beauge, Louis Lantier, et al. "846 Neospora caninum – an immunotherapeutic protozoan against solid cancers." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A899. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0846.

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BackgroundImmunotherapy induces, provides, and/or reactivates anti-tumor immune responses. Some microorganisms also can initiate response that lyzes infected tumor and/or stimulates systemic immunity. Attenuated viruses or bacteria are well studied as oncotherapeutics, but not protozoa except Toxoplasma gondii.1 We assessed the effect on tumors of other protozoa that were naturally non-pathogenic to humans. Thus, we discovered the ability to use Neospora caninum (Nc) in a manner and form that demonstrated a synergistic array of pertinent immunotherapeutic characteristics against solid cancers.
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AbdRabou, Mervat Ahmed, Ahmed B. M. Mehany, Islam M. Farrag, et al. "Therapeutic Effect of Murine Bone Marrow-Derived Mesenchymal Stromal/Stem Cells and Human Placental Extract on Testicular Toxicity Resulting from Doxorubicin in Rats." BioMed Research International 2021 (August 6, 2021): 1–13. http://dx.doi.org/10.1155/2021/9979670.

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Oncotherapeutics like doxorubicin can affect male gonads; as a result, it leads to infertility. This work was conducted to demonstrate the toxic effects of doxorubicin on testes of male albino rats. Fifty male albino rats aged 5-7 weeks were used in this study. The animals were randomly separated into 5 sets (each set containing ten rats). Group I received saline (i.p.) for 4 weeks. Group II was given doxorubicin (DOX), 5 mg/kg BW (i.p.) once/week for 4 weeks. Groups III and IV were treated in the same way as the DOX group, left for one week without medication, and then injected with mesenchym
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Chhajed, Santosh Subhash, Pramodkumar P. Gupta, Sanjay Kshirsagar, Sakshi Tomar, Debarshi Kar Mahapatra, and Raji Sundararajan. "N-(2-(1H-benzo[d]imidazol-2-yl)Phenyl)-2- (Substituted-styryl)Aniline as Anti-proliferative Agents: Rejuvenating the Importance of Low Molecular Weight Ligands in Oncotherapeutics." Indian Journal of Pharmaceutical Education and Research 54, no. 2 (2020): 432–39. http://dx.doi.org/10.5530/ijper.54.2.49.

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Dissertations / Theses on the topic "ONCOTHERAPEUTICS"

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KAR, ROHAN. "STUDYING THE MIR-24 EXPRESSION PROFILE IN BREAST CARCINOMAS AND SYNTHESIS OF LIPOSOMES AS NANOVEHICLES FOR SIRNA BASED FUTURE ONCOTHERAPEUTICS." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/14998.

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Breast cancer related mortalities are currently on the rise and hence the need for model therapeutics to improve survival and quality of life in patients is a prime necessity. Much of the prognosis and tumour behaviour in patients are controlled by the cancer stem cells, which ultimately leads to chemotherapeutic resistance and disease recurrence. MiRNA are short non-coding RNAs with potential roles in carcinogenesis and mRNA silencing. miRNA-24 could be a probable regulator of epithelial to mesenchymal transition (EMT) mediated via Klf-8 and Notch-1. However, the exact mechanism for miR-24, K
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Books on the topic "ONCOTHERAPEUTICS"

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Novel Molecular Oncotargets and Nano-Oncotherapeutics. Cambridge Scholars Publishing, 2023.

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Book chapters on the topic "ONCOTHERAPEUTICS"

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Baba, Abdul Basit, Rajakishore Mishra, and Siddavaram Nagini. "Survivin, a Moonlighting Caspase Inhibitor and Potential Oncotherapeutic Target." In Handbook of Proteases in Cancer. CRC Press, 2024. http://dx.doi.org/10.1201/9781003394693-12.

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Patel, Alkeshkumar. "Drug Repurposing in Oncotherapeutics." In Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92302.

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Repurposing or repositioning means validating and application of previously approved drugs in the treatment of another disease that might be relevant or irrelevant to existing use in disease based on the principle of polypharmacology. Repurposed drugs are already well documented for pharmacokinetic, pharmacodynamic, drug interaction, and toxicity parameters. In 1962, thalidomide treatment in pregnant women led to phocomelia in their newborn but while repurposed based on anti-angiogenesis property, it showed efficacy in hematologic malignancies like multiple myeloma. The repurposing is becoming
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Rashid, Nowsheeba, Rouf Ahmad Bhat, Nighat Mushtaq, and Ifra Ashraf. "Exploitation of revered potent medicinal mushroom Ganoderma lucidum with particular accent on oncotherapeutics." In Medicinal and Aromatic Plants. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-819590-1.00015-x.

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Sen, Shinjini, and Banashree Bondhopadhyay. "The Role of Terpenes in Cancer Management." In Analyzing Terpenes' Role in Cancer Treatment. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-6972-2.ch008.

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Terpenes are a broad and varied group of organic compounds found in numerous plants, especially conifers, and some insects. They are known for imparting aromatic properties to these organisms. Recently, there is a growing interest in terpenes due to their wide-range of applications and increase in demand for natural products. This surge in interest is particularly evident in the cosmetic, pharmaceutical, and food industries, where the demand for natural and organic ingredients has significantly boosted the appeal of terpenes. Additionally, their role in traditional medicine provided a historic
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Conference papers on the topic "ONCOTHERAPEUTICS"

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Shipunova, V. O., E. N. Komedchikova, A. V. Pushkarev, et al. "Targeted PLGA nanoparticles as versatile platfrom for the delivery of oncotherapeutic compounds." In 2024 International Conference Laser Optics (ICLO). IEEE, 2024. http://dx.doi.org/10.1109/iclo59702.2024.10624455.

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You might also be interested in the extended bibliographies on the topic 'ONCOTHERAPEUTICS' for particular source types:
Journal articles
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