Academic literature on the topic 'Ophthalmic inserts'

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Journal articles on the topic "Ophthalmic inserts"

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Nidhi A. Bagmar, Pooja R. Hatwar, Prashant G. Shelke, and Dr. Ravindra L. Bakal. "A Review on "Ocuserts (An Ophthalmic Insert)”." Asian Journal of Pharmaceutical Research and Development 12, no. 6 (2024): 131–39. https://doi.org/10.22270/ajprd.v12i6.1460.

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The eye is God's most wonderful creation of all the sense organs in the human body since it allows us to see numerous objects both near and far away. An ocular implant is a cutting-edge device for treating eye diseases. The design and development of an ocular insert has always been a difficulty for pharmaceutical researchers and manufacturers. Ocuserts, also known as ophthalmic inserts, are "sterile preparations in the form of solid or semisolid, whose size and shape are specially designed to be applied to the eyes". Solvent casting, the Glass Substrate technique, and hot melt extrusion were u
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Patel, U.L. "Formulation and in vitro evaluation of moxifloxacin ophthalmic inserts." International Journal of Pharmaceutical Research 1, no. 1 (2009): 23–30. https://doi.org/10.5281/zenodo.8151862.

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Gurtler, F., and R. Gurny. "Patent Literature Review of Ophthalmic Inserts." Drug Development and Industrial Pharmacy 21, no. 1 (1995): 1–18. http://dx.doi.org/10.3109/03639049509048094.

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Dumitriu, Severian, Marcel Popa, Petre Vancea, and Danut Costin. "Polycomponent Ophthalmic Inserts with Polysaccharide Support." Journal of Bioactive and Compatible Polymers 3, no. 4 (1988): 370–89. http://dx.doi.org/10.1177/088391158800300404.

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Dabral, Kriti, and Yashika Uniyal. "Ocular inserts: Novel approach for drug delivery into eyes." GSC Biological and Pharmaceutical Sciences 7, no. 3 (2019): 001–7. https://doi.org/10.5281/zenodo.4286037.

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As an isolated organ, it is difficult to study eye from a drug delivery point of view. Ophthalmic drug delivery is extremely interesting and highly challenging attempt.  In recent scenario, most eye-diseases are treated with topical application of eye-drops. But these conventional eye-drops have two major problems. One is it needs frequent administration at every 4 hours or 1 hour if the infection is severe and another is formation of crystalline deposits on cornea due to its pH-dependent solubility which is very low. In order to provide the solution of above problems many novel formulati
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Omer, Safaa, and Romána Zelkó. "A Systematic Review of Drug-Loaded Electrospun Nanofiber-Based Ophthalmic Inserts." Pharmaceutics 13, no. 10 (2021): 1637. http://dx.doi.org/10.3390/pharmaceutics13101637.

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Currently, ocular inserts and nanoparticles have received much attention due to the limited bioavailability of conventional eye preparations and the toxicity problems of systemic drug administration. The current systematic review aims to present recent studies on the use of electrospun nanofiber-based ocular inserts to improve the bioavailability of drugs used for different ophthalmic diseases. A systematic search was performed in PubMed, Ovid Medline, Web of Science, ScienceDirect, Scopus, Reaxys, Google Scholar, and Google Patents/Espacenet taking “drug-loaded”, “nanofibers”, and “ophthalmic
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Vasantha, V., P. K. Sehgal, and K. Panduranga Rao. "Collagen ophthalmic inserts for pilocarpine drug delivery system." International Journal of Pharmaceutics 47, no. 1-3 (1988): 95–102. http://dx.doi.org/10.1016/0378-5173(88)90219-0.

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Devhadrao, NV, and M. Siddhaia. "REVIEW ON OCULAR INSERT DRUG DELIVERY SYSTEM." Journal of Drug Delivery and Therapeutics 8, no. 5-s (2018): 115–21. http://dx.doi.org/10.22270/jddt.v8i5-s.1991.

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An ocular insert represents an advanced technology in eye disease therapy. Designing and development of an ocular insert is a challenge ever faced by Pharmaceutical researchers or manufacturer. In the ophthalmology; eye drop have ever found to be an easy remedy from the administration point of view. In case of conventional dosage forms the fast precorneal loss of drug has been a major difficulty. To improve ocular drug bioavailability, there are significant guidelines have been directed towards newer drug delivery systems for ophthalmic administration. By means of ocular insert, the researcher
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Grimaudo, Maria Aurora, Angel Concheiro, and Carmen Alvarez-Lorenzo. "Crosslinked Hyaluronan Electrospun Nanofibers for Ferulic Acid Ocular Delivery." Pharmaceutics 12, no. 3 (2020): 274. http://dx.doi.org/10.3390/pharmaceutics12030274.

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Electrospun nanofibers are gaining interest as ocular drug delivery platforms that may adapt to the eye surface and provide sustained release. The aim of this work was to design an innovative ophthalmic insert composed of hyaluronan (HA) nanofibers for the dual delivery of an antioxidant (ferulic acid, FA) and an antimicrobial peptide (ε-polylysine, ε-PL). Polyvinylpyrrolidone (PVP) was added to facilitate the electrospinning process. Fibers with diameters of approx. 100 nm were obtained with PVP 5%-HA 0.8% w/v and PVP 10%-HA 0.5% w/v mixtures in ethanol:water 4:6 v/v. An increase in PVP conce
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Guadarrama-Escobar, Omar Rodrigo, Cassandra Araceli Valdés-Alvarez, Karla Stella Constantino-Gonzalez, et al. "Design and Characterization of Ocular Inserts Loaded with Dexamethasone for the Treatment of Inflammatory Ophthalmic Disease." Pharmaceutics 16, no. 2 (2024): 294. http://dx.doi.org/10.3390/pharmaceutics16020294.

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The short precorneal residence time of ophthalmic drops is associated with their low absorption; therefore, the development of ocular inserts capable of prolonging and controlling the ophthalmic release of drugs is an interesting option in the design and development of these drugs. A surface response design was developed, specifically the Central Composite Design (CCD), to produce ophthalmic films loaded with Dexamethasone (DEX) by the solvent evaporation method having experimental levels of different concentrations of previously selected polymers (PVP K-30 and Eudragit RS100.). Once optimizat
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Book chapters on the topic "Ophthalmic inserts"

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Salminen, L. "Pilocarpine Inserts: Experimental and Clinical Experiences." In Ophthalmic Drug Delivery. Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4757-4175-9_16.

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"Bioadhesive Ophthalmic Drug Inserts (BODI)." In Modified-Release Drug Delivery Technology. CRC Press, 2002. http://dx.doi.org/10.1201/9780203910337-31.

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Gurny, R., and Olivia Felt-Baeyens. "Bioadhesive Ophthalmic Drug Inserts (BODI)." In Drugs and the Pharmaceutical Sciences. Informa Healthcare, 2002. http://dx.doi.org/10.1201/9780203910337.ch28.

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Ngo, William, Chau Minh-Phan, and Alex Hui. "Anterior Segment Drug Delivery." In Ophthalmic Biomaterials. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781839169779-00311.

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Drug delivery to the anterior segment of the eye presents numerous challenges, as the inherent barriers and anatomy of the eye need to be taken into account or overcome to allow for sufficient concentrations of pharmaceuticals to be reached in structures of concern. This chapter will provide an overview of the pharmacokinetic considerations of drug delivery to the anterior segment, as well as the numerous means to deliver drugs to anterior ocular structures, including eye drops, contact lenses, ocular inserts, and iontophoresis.
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Furrer, Pascal, Olivia Felt, and Robert Gurny. "Bioadhesive Ophthalmic Drug Inserts (BODI) for Veterinary Use." In Modified-Release Drug Delivery Technology, Second Edition. CRC Press, 2008. http://dx.doi.org/10.3109/9781420045260-8.

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