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Journal articles on the topic 'Optical Coherence Tomography Angiography (OCTA)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Dita Mintardi, AK Ansyori, and Ramzi Amin. "Optical Coherence Tomography Angiography." Sriwijaya Journal of Ophthalmology 2, no. 1 (2019): 46–54. http://dx.doi.org/10.37275/sjo.v2i1.20.

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Optical Coherence Tomography Angiography (OCTA) is a new high-resolution imaging method for visualizing retinal and choroidal circulation without any dye injection By detecting intravascular flow quickly when needed and being able to repeat images, as often as needed, without risk to patients, doctors will value OCTA as one of the most important applications of OCT imaging because of its ability to offer precise visualization of intravascular flow in the inner retina layer and outside, as well as the inner choroid. OCTA uses high-speed structural OCT imaging and provides three-dimensional data

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Hautz, Wojciech, Joanna Gołębiewska, and Beata Kocyła-Karczmarewicz. "Optical Coherence Tomography and Optical Coherence Tomography Angiography in Monitoring Coats’ Disease." Journal of Ophthalmology 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/7849243.

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Purpose. The aim of this study was to evaluate the usefulness of optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in monitoring pediatric patients with Coats’ disease.Material and Methods. This retrospective study included 9 Caucasian patients receiving treatment for Coats’ disease at the Children’s Memorial Health Institute Ophthalmology Department between December 2014 and May 2016. The course of the disease was monitored with OCTA in combination with OCT and fluorescein angiography (FA).Results. OCT B-scans obtained in all patients correlated with FA fi

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Wang, Chung-Ting, Yin-Hsi Chang, Gavin S. W. Tan, et al. "Optical Coherence Tomography and Optical Coherence Tomography Angiography in Pediatric Retinal Diseases." Diagnostics 13, no. 8 (2023): 1461. http://dx.doi.org/10.3390/diagnostics13081461.

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Indirect ophthalmoscopy and handheld retinal imaging are the most common and traditional modalities for the evaluation and documentation of the pediatric fundus, especially for pre-verbal children. Optical coherence tomography (OCT) allows for in vivo visualization that resembles histology, and optical coherence tomography angiography (OCTA) allows for non-invasive depth-resolved imaging of the retinal vasculature. Both OCT and OCTA were extensively used and studied in adults, but not in children. The advent of prototype handheld OCT and OCTA have allowed for detailed imaging in younger infant

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Blackorby, Barton L., and Bradley T. Smith. "Optical Coherence Tomography Angiography: Practical Usefulness." Journal of VitreoRetinal Diseases 3, no. 3 (2019): 153–66. http://dx.doi.org/10.1177/2474126419833590.

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Purpose: The purpose of this article is to highlight the practical usefulness of optical coherence tomography angiography (OCTA) in the management of a spectrum of retinal diseases and support it as a reimbursable diagnostic tool by third-party payers. Methods: Case presentations are discussed. Results: Noninvasive OCTA provides information to guide clinical decision making, prognosis, and treatment response across a wide variety of retinal disorders. Conclusions: OCTA is able to detect ischemic and neovascular processes in numerous retinal diseases and is valuable for diagnosis and treatment.

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Yao, Xincheng, Minhaj N. Alam, David Le, and Devrim Toslak. "Quantitative optical coherence tomography angiography: A review." Experimental Biology and Medicine 245, no. 4 (2020): 301–12. http://dx.doi.org/10.1177/1535370219899893.

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As a new optical coherence tomography (OCT) modality, OCT angiography (OCTA) provides a noninvasive method to detect microvascular distortions correlated with eye conditions. By providing unparalleled capability to differentiate individual plexus layers in the retina, OCTA has demonstrated its excellence in clinical management of diabetic retinopathy, glaucoma, sickle cell retinopathy, diabetic macular edema, and other eye diseases. Quantitative OCTA analysis of retinal and choroidal vasculatures is essential to standardize objective interpretations of clinical outcome. Quantitative features,

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Son, Taeyoon, Minhaj Alam, Tae-Hoon Kim, Changgeng Liu, Devrim Toslak, and Xincheng Yao. "Near infrared oximetry-guided artery–vein classification in optical coherence tomography angiography." Experimental Biology and Medicine 244, no. 10 (2019): 813–18. http://dx.doi.org/10.1177/1535370219850791.

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Differential artery–vein analysis is valuable for early detection of diabetic retinopathy and other eye diseases. As a new optical coherence tomography imaging modality, optical coherence tomography angiography provides capillary level resolution for accurate examination of retinal vasculatures. However, differential artery–vein analysis in optical coherence tomography angiography particularly for macular region in which blood vessels are small is challenging. In coordination with an automatic vessel tracking algorithm, we report here the feasibility of using near infrared optical coherence to

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7

Carlo, Talisa E. de. "Advances in Optical Coherence Tomography Angiography." US Ophthalmic Review 09, no. 01 (2016): 37. http://dx.doi.org/10.17925/usor.2016.09.01.37.

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Optical coherence tomography angiography (OCTA) is an exciting new imaging technology that allows for non-invasive non-dye-based visualization of blood flow in the posterior pole. The technology has been used to image a variety of chorioretinal disorders including choroidal neovascularization in age-related macular degeneration, diabetic retinopathy, retinal arterial occlusion, retinal vein occlusion, and macular telangiectasia type 2. Continued advances in the software will improve the quality of OCTA and reduce image artifacts.

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Paczwa, Katarzyna, and Joanna Gołębiewska. "OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN OPHTHALMOLOGY." Polish Journal of Aviation Medicine, Bioengineering and Psychology 26, no. 4 (2023): 45–54. http://dx.doi.org/10.13174/pjambp.17.05.2023.05.

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Abstract: Optical coherence tomography is a non-invasive method of imagining the anterior and the posterior segment of the eye. It is commonly used in ophthalmic practice to diagnose and monitor various pathologies of the eyeball. Optical coherence tomography angiography (OCTA) is a useful tool to visualize the entire retinal and choroidal microvasculature, allowing the assessment of retinal perfusion without intravenous dye administration.

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9

Iuliano, Lorenzo. "Optical Coherence Tomography Angiography of Choroidal Neovascularisation." European Ophthalmic Review 10, no. 01 (2016): 29. http://dx.doi.org/10.17925/eor.2016.10.01.29.

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Optical coherence tomography angiography (OCTA) is a new promising technique able to provide a rapid, dyeless and non-invasive three-dimensional reconstruction of perfused vessels of retina and choroid. OCTA has been recently added to the diagnostic tools of retinal experts, and its role is still being explored in different retinal diseases. Chorodial neovascularisations (CNVs) are among the most significant disorders where OCTA is enhancing our diagnostic and classification skills, since it demonstrates an excellent capacity to identify and characterise each specific subtype of CNV.

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Gupta, Priyanka, Daraius Shroff, and Charu Gupta. "Unveiling the Optical Coherence Tomography Angiography Artifacts." Delhi Journal of Ophthalmology 34, no. 3 (2024): 176–81. https://doi.org/10.4103/dljo.dljo_60_24.

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Optical coherence tomography angiography (OCTA) is a promising novel method for visualizing the microvasculature of the retina and choroidal vascular layers in the macular area. It provides depth-resolved functional and structural information on blood flow in the vessels. OCTA is based on the principle of motion contrast. Artifacts can arise from optical coherence tomography (OCT) image acquisition, intrinsic characteristics of the eye, eye motion, image processing, and display techniques. There are several algorithms available that have the potential to visualize flow, but all have image arti

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Nagpal, Manish, and Gujarat India. "Optical Coherence Tomography Angiography." US Ophthalmic Review 11, no. 2 (2018): 91. http://dx.doi.org/10.17925/usor.2018.11.2.91.

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Optical coherence tomography angiography (OCTA) is a new revolutionary non-invasive imaging modality, built on the platform of optical coherence tomography (OCT). This technique works on the principle of ‘decorrelation’ and is still a nascent technology in its infancy with tremendous potential applicability for diagnosing retinal and choroidal vascular diseases. Its non-invasive nature, and the ability to generate images of retinal and choroidal vasculature, allows it to replace and/or supplement the current angiographic gold standards, fluorescein angiography (FA) and indocyanine green angiog

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Amato, Alessia, Francesco Nadin, Federico Borghesan, et al. "Widefield Optical Coherence Tomography Angiography in Diabetic Retinopathy." Journal of Diabetes Research 2020 (November 24, 2020): 1–10. http://dx.doi.org/10.1155/2020/8855709.

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Purpose. To summarize the role of widefield optical coherence tomography angiography (WF-OCTA) in diabetic retinopathy (DR), extending from the acquisition strategies to the main clinical findings. Methods. A PubMed-based search was carried out using the terms “Diabetic retinopathy”, “optical coherence tomography angiography”, “widefield imaging”, and “ultra-widefield imaging”. All studies published in English up to August 2020 were reviewed. Results. WF-OCTA can be obtained with different approaches, offering advantages over traditional imaging in the study of nonperfusion areas (NPAs) and ne

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Turgut, Burak. "Optical Coherence Tomography Angiography – A General View." European Ophthalmic Review 10, no. 01 (2016): 39. http://dx.doi.org/10.17925/eor.2016.10.01.39.

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Optical coherence tomography angiography (OCTA) is a non-invasive angiography type without a contrast agent, which provides a detailed assessment of the retinal and choroidal vasculature and visualisation of blood flow by detecting motions of erythrocytes, using serial optical coherence tomography B-scans. OCTA has been thoroughly investigated during imaging of the microvasculature in various retinal and choroidal vascular and tumoural diseases that affect the central macula. It has some important advantages and some acceptable disadvantages.

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Ong, Charles Jit Teng, Mark Yu Zheng Wong, Kai Xiong Cheong, Jinzhi Zhao, Kelvin Yi Chong Teo, and Tien-En Tan. "Optical Coherence Tomography Angiography in Retinal Vascular Disorders." Diagnostics 13, no. 9 (2023): 1620. http://dx.doi.org/10.3390/diagnostics13091620.

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Traditionally, abnormalities of the retinal vasculature and perfusion in retinal vascular disorders, such as diabetic retinopathy and retinal vascular occlusions, have been visualized with dye-based fluorescein angiography (FA). Optical coherence tomography angiography (OCTA) is a newer, alternative modality for imaging the retinal vasculature, which has some advantages over FA, such as its dye-free, non-invasive nature, and depth resolution. The depth resolution of OCTA allows for characterization of the retinal microvasculature in distinct anatomic layers, and commercial OCTA platforms also

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Shpak, A. A., and N. A. Morina. "Terminology of optical coherence tomography angiography metrics." Fyodorov journal of ophthalmic surgery 143, no. 1 (2025): 82–86. https://doi.org/10.25276/0235-4160-2025-1-82-86.

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Purpose To analyze the basic terminology of OCTA metrics and to provide guidance on the terminology use. Material and methods The analysis of manuals for OСTA devices of various manufacturers and databases PubMed and eLIBRARY. Results The recommendations were given, that ensure uniformity of described terms that characterize the main quantitative metrics of OCTA. In particular, it is recommended to provide a detailed definition of these terms in the work. Key words: optical coherence tomography angiography, vessel density, perfusion density, terminology

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Pomytkina, N. V., and E. L. Sorokin. "Possibilities of diagnostic monitoring of diabetic retinopathy using optical coherence tomography angiography." Modern technologies in ophtalmology, no. 3 (June 1, 2023): 163–76. http://dx.doi.org/10.25276/2312-4911-2023-3-163-176.

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Optical coherence tomography angiography (OCTA) is an advanced noninvasive method of 3D imaging and quantitative analysis of the retinal and choroidal microvasculature. It allows detecting manifestation and progression of diabetic retinopathy, planning treatment and evaluating its results. OCTA expands our understanding of microvascular changes in retinal vascular plexuses in different stages of disease and deepens understanding of its pathogenesis. Keywords: optical coherence tomography angiography; fluorescein angiography; diabetic retinopathy; foveal avascular zone; retinal blood flow

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Liu, Mengyang, and Wolfgang Drexler. "Optical coherence tomography angiography and photoacoustic imaging in dermatology." Photochemical & Photobiological Sciences 18, no. 5 (2019): 945–62. http://dx.doi.org/10.1039/c8pp00471d.

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Costanzo, Eliana, Salomon Yves Cohen, Alexandra Miere, et al. "Optical Coherence Tomography Angiography in Central Serous Chorioretinopathy." Journal of Ophthalmology 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/134783.

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Purpose. To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them with those obtained with multimodal imaging.Methods. A series of consecutive patients diagnosed with CSC, underwent OCTA and multimodal imaging, including spectral domain OCT, fluorescein, and indocyanine green angiography. OCTA images were performed at three main depth intervals: automatically segmented outer retina, manually adjusted outer retina, and automatically segmented choriocapillaris.Results. Thirty-three eyes of 32 consecutive patients

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Vaz-Pereira, Sara, Tiago Morais-Sarmento, and Michael Engelbert. "Update on Optical Coherence Tomography and Optical Coherence Tomography Angiography Imaging in Proliferative Diabetic Retinopathy." Diagnostics 11, no. 10 (2021): 1869. http://dx.doi.org/10.3390/diagnostics11101869.

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Proliferative diabetic retinopathy (PDR) is a major cause of blindness in diabetic individuals. Optical coherence tomography (OCT) and OCT-angiography (OCTA) are noninvasive imaging techniques useful for the diagnosis and assessment of PDR. We aim to review several recent developments using OCT and discuss their present and potential future applications in the clinical setting. An electronic database search was performed so as to include all studies assessing OCT and/or OCTA findings in PDR patients published from 1 January 2020 to 31 May 2021. Thirty studies were included, and the most recent

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Ong, Patel, and Singh. "Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases." Journal of Clinical Medicine 8, no. 12 (2019): 2078. http://dx.doi.org/10.3390/jcm8122078.

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Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy,

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Bhattacharyya, Sampurna, Zubin D'souza, Raghulnadhan Ramanadhane, et al. "Pupil vignetting artifact on optical coherence tomography angiography." Indian Journal of Ophthalmology 72, Suppl 1 (2023): S135—S139. http://dx.doi.org/10.4103/ijo.ijo_812_23.

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Purpose: To discuss the features of an artifact on optical coherence tomography angiography (OCTA), termed “pupil vignetting artifact,” and describe how it may masquerade as true chorioretinal pathology. Design: This was a retrospective, observational case series. Methods: The authors studied 12 eyes at a vitreoretinal clinic in Eastern India, reviewing a dark shadow such as an artifact on OCTA images. Results: In all 12 eyes, there was an appearance of a dark shadow on OCTA imaging, located at the macula, superior, superotemporal, or superonasal to the fovea, which did not correspond to any i

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Gaber, Manal, Khaled Mourad, Hossam Moharram, and Mohamed Ahmed. "Optical Coherence Tomography Angiography (OCTA): Article review." Minia Journal of Medical Research 30, no. 4 (2019): 317–23. http://dx.doi.org/10.21608/mjmr.2022.221747.

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Duncan, Grant. "Optical coherence tomography angiography (OCTA) – a review." Optician 2018, no. 3 (2018): 6896–1. http://dx.doi.org/10.12968/opti.2018.3.6896.

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Ulfik-Dembska, Klaudia, Sławomir Teper, Michał Dembski, Anna Nowińska, and Edward Wylęgała. "Idiopathic Epiretinal Membrane: Microvasculature Analysis with Optical Coherence Tomography and Optical Coherence Tomography Angiography." Tomography 8, no. 1 (2022): 189–99. http://dx.doi.org/10.3390/tomography8010016.

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Background: The present study examined the relationships among macular microvasculature, retinal structure, and epiretinal membrane (ERM) and explored the utility of optical coherence tomography (OCT) angiography (OCTA) in idiopathic ERM assessment. Methods: The study sample comprised 276 eyes of 276 patients. A total of 154 eyes with ERM and 122 normal (control) eyes were analyzed. Only one eye of each participant was randomly selected for posterior segment imaging. Each patient underwent OCT and OCTA. Images were analyzed with AngioTool 0.6. Results: Foveal avascular zone was significantly s

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Holló, Gábor. "Optical Coherence Tomography Angiography to Better understand Glaucoma." Journal of Current Glaucoma Practice 11, no. 2 (2017): 35–37. http://dx.doi.org/10.5005/jp-journals-10028-1219.

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ABSTRACT The term optical coherence tomography angiography (OCTA) comprises different OCT-based technologies which all allow noninvasive assessment of retinal perfusion, based on moving red blood cells. The main areas where OCTA is currently used are investigation of perfusion and vascular structure of the macular retina (e.g., in macular degenerations and diabetic macular diseases) and the disk and peripapillary retina (in glaucoma and other optic disk diseases). The current editorial provides a brief overview on the potential of OCTA and its use to measure perfusion in the peripapillary reti

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Mayur, Kulkarni, Bharambe Mohit, and Kulkarni Gauri. "Optical Coherence Tomography Angiography versus Fundus Fluorescein Angiography in Assessing Age-Related Macular Degeneration: A Retrospective Study." PJSR 13, no. 1 (2019): 1–7. https://doi.org/10.5281/zenodo.8237792.

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Optical coherence tomography angiography (OCTA) could be a valid tool to detect choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD), allowing the analysis of the type, the morphology, and the extension of CNV in most of the cases.  This retrospective cross-sectional study, aimed to highlight the role of optical coherence tomography angiography (OCTA) as compared to fluorescein angiography (FA) in the evaluation of age related macular degeneration (AMD).was conducted at tertiary eye care centre. This study enrolled 24 patients (48 eyes). All patients u

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Chua, Jacqueline, Ralene Sim, Bingyao Tan, et al. "Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy." Journal of Clinical Medicine 9, no. 6 (2020): 1723. http://dx.doi.org/10.3390/jcm9061723.

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Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the retinal microvasculature and is a leading cause of vision loss globally. Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood cells. OCTA offers numerous benefits over traditional fluorescein angiography in visualizing the retinal vasculature in that it is non-invasive and safer; while its depth-resolved ability makes it possible to visualize the finer capilla

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Ahmed-Balestra, Daniel, Alexandra Graf, Martin Stattin, et al. "Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians." Journal of Ophthalmology 2023 (June 13, 2023): 1–11. http://dx.doi.org/10.1155/2023/9597673.

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Purpose. The aim of the study is to analyze the swept source-optical coherence tomography angiography (SS-OCTA) characteristics of polypoidal lesions in Caucasian patients. Methods. In this retrospective observational case series, 43 polypoidal lesions in 32 eyes of 32 patients were diagnosed using indocyanine green angiography (ICGA) and compared to SS-OCTA at a tertiary medical retina center (Clinic Landstraße, Vienna Healthcare Group, Austria) between June 2017 and March 2020. Vascularity was identified by color-coded B-scan SS-OCTA while morphology was described as revealed by en face SS-O

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Gonzalez, Marco A., Diana Shechtman, Jay M. Haynie, and Leo Semes. "Unveiling Idiopathic Macular Telangiectasia: Clinical Applications of Optical Coherence Tomography Angiography." European Journal of Ophthalmology 27, no. 4 (2017): e129-e133. http://dx.doi.org/10.5301/ejo.5000984.

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Purpose Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly useful in the assessment and ma

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van de Kreeke, Jacoba Alida, Hoang-Ton Nguyen, Elles Konijnenberg, et al. "Optical coherence tomography angiography in preclinical Alzheimer’s disease." British Journal of Ophthalmology 104, no. 2 (2019): 157–61. http://dx.doi.org/10.1136/bjophthalmol-2019-314127.

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Background/aimsAs a protrusion from the brain, the retina might reflect the status of the brain. Previous studies showed a decrease in vessel density and foveal avascular zone (FAZ) enlargement on optical coherence tomography angiography (OCTA) in individuals suffering from Alzheimer’s disease (AD). This study aims to assess whether such changes are already present in preclinical stages of AD, in a population of monozygotic (MZ) twins.Methods124 cognitively healthy individuals (MZ twins, ages 60–93 years) underwent [18F]flutemetamol amyloid positron emission tomography (PET) scanning and OCTA.

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Garcia, Jose Mauricio Botto de Barros, Talita Toledo Lima, Ricardo Noguera Louzada, Alessandra Thome Rassi, David Leonardo Cruvinel Isaac, and Marcos Avila. "Diabetic Macular Ischemia Diagnosis: Comparison between Optical Coherence Tomography Angiography and Fluorescein Angiography." Journal of Ophthalmology 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/3989310.

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Purpose. To compare fluorescein angiography (FA) and optical coherence tomography angiography (OCTA) images of foveal avascular zone (FAZ) in patients with diabetic retinopathy (DR) with and without diabetic macular ischemia (DMI).Methods. The Wilcoxon signed-rank test was used to compare area measurements andpvalues of <0.05 were considered statistically significant. FA and OCTA images were independently graded by 2 observers that reached agreement regarding quantitative DMI according established protocols. The ischemic area was divided into “large” macular ischemia (superior to 0.32 mm2)

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Wu, Shuo-chieh, Victor M. Villegas, and Jaclyn L. Kovach. "Optical Coherence Tomography Angiography of Combined Central Retinal Artery and Vein Occlusion." Case Reports in Ophthalmological Medicine 2018 (2018): 1–4. http://dx.doi.org/10.1155/2018/4342158.

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Optical coherence tomography angiography (OCTA) is a new, noninvasive technology that enables detailed evaluation of flow in the retinal and choroidal vasculature. The authors believe this to be the first report to describe the optical coherence tomography angiography findings associated with combined central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO).

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Mayur, Kulkarni, Bharambe Mohit, and Kulkarni Gauri. "Optical Coherence Tomography Angiography versus Fundus Fluorescein Angiography in Assessing Age- Related Macular Degeneration: A Retrospective Study." PJSR 12, no. 1 (2019): 1–7. https://doi.org/10.5281/zenodo.8245376.

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Optical coherence tomography angiography (OCTA) could be a valid tool to detect choroidal neovascularization  (CNV) in neovascular age-related macular degeneration (nAMD), allowing the analysis of the type, the morphology, and the  extension of CNV in most of the cases.   This retrospective cross-sectional study, aimed to highlight the role of optical  coherence tomography angiography (OCTA) as compared to fluorescein angiography (FA) in the evaluation of age related  macular degeneration (AMD).was conducted at tertiary eye care centre. This study enrolled 24 patients

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Batıoğlu, Figen, Özge Yanık, Sibel Demirel, and Emin Özmert. "Clinical Use of Optical Coherence Tomography Angiography in Retinal Diseases." Diagnostics 13, no. 10 (2023): 1820. http://dx.doi.org/10.3390/diagnostics13101820.

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The advent of optical coherence tomography angiography (OCTA) is one of the cornerstones of fundus imaging. Essentially, its mechanism depends on the visualization of blood vessels by using the flow of erythrocytes as an intrinsic contrast agent. Although it has only recently come into clinical use, OCTA has become a non-invasive diagnostic tool for the diagnosis and follow-up of many retinal diseases, and the integration of OCTA in multimodal imaging has provided a better understanding of many retinal disorders. Here, we provide a detailed overview of the current applications of OCTA technolo

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Sodhi, Punita Kumari, Anu Sharma, and Nasiq Hasan. "Optical Coherence Tomography Angiography following Scleral Buckling Surgery." Nepalese Journal of Ophthalmology 13, no. 1 (2021): 165–70. http://dx.doi.org/10.3126/nepjoph.v13i1.30652.

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Introduction: The retinal changes following scleral buckling surgery (SBS) for rhegmatogenous retinal detachment (RRD) have been rarely evaluated with optical coherence tomography angiography (OCTA). Methods: A 40 years old male presented with subtotal RD involving the macula and had best corrected visual acuity of logmar 2.3 in the affected right eye. Five months after applying 120 degree scleral buckle, swept source optical coherence tomography (SSOCT) and swept source optical coherence tomography angiography (SS-OCTA) were done.  Result: At five months post-surgery, despite a se

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Rajabian, Firuzeh, Alessandro Arrigo, Lorenzo Bianco, et al. "Optical Coherence Tomography Angiography in CRB1-Associated Retinal Dystrophies." Journal of Clinical Medicine 12, no. 3 (2023): 1095. http://dx.doi.org/10.3390/jcm12031095.

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Aim of the study: To report optical coherence tomography angiography (OCTA) findings in patients affected by CRB1-associated retinal dystrophies. Method: Patients affected by a genetically confirmed CRB1-associated retinal dystrophy were prospectively enrolled in an observational study, along with age- and sex-matched healthy volunteers as control subjects. All study and control subjects received a complete ophthalmic examination and multimodal retinal imaging, including OCTA. Result: A total of 12 eyes from 6 patients were included in the study. The mean BCVA of patients was 0.42 ± 0.25 logMA

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Matulevičiūtė, Indrė, Agnė Sidaraitė, Vacis Tatarūnas, Audronė Veikutienė, Olivija Dobilienė, and Dalia Žaliūnienė. "Retinal and Choroidal Thinning—A Predictor of Coronary Artery Occlusion?" Diagnostics 12, no. 8 (2022): 2016. http://dx.doi.org/10.3390/diagnostics12082016.

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Introduction. Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) allowed visualization of retina and choroid to nearly the capillary level; however, the relationship between systemic macrovascular status and retinal microvascular changes is not yet known well. Aim. Our purpose was to assess the impact of retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) parameters on prediction of coronary heart disease (CHD) in acute myocardial infarction (MI) and chronic three vessel disease (3VD) groups. Methods. This observati

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Allegrini, Davide, Giovanni Montesano, and Alfredo Pece. "Optical Coherence Tomography Angiography of Iris Nevus: A Case Report." Case Reports in Ophthalmology 7, no. 3 (2016): 450–56. http://dx.doi.org/10.1159/000450572.

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Iris nevus is common: 6% of patients with suspected iris melanoma have lesions other than melanoma, and 36% of them are nevi. Iris nevus turns into melanoma in approximately 8% of cases at a mean of 15 years. This case report provides the first description of an iris tumor examined with iris optical coherence tomography angiography (OCTA) compared to iris fluorescein angiography (IFA). A 60-year-old man with a diagnosis of iris nevus in the left eye was referred to our department for IFA and iris OCTA. The iris vasculature in IFA was visible only in the early phases, but not clearly. OCTA, how

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Michalewska, Zofia, and Jerzy Nawrocki. "Swept-Source Optical Coherence Tomography Angiography in Central Serous Chorioretinopathy." Journal of VitreoRetinal Diseases 2, no. 6 (2018): 351–57. http://dx.doi.org/10.1177/2474126418794578.

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Purpose: This article aims to evaluate the appearance of central serous chorioretinopathy (CSC) with swept-source optical coherence tomography angiography (SS-OCTA), to discuss whether localization of the leakage spot seen on fluorescein angiography (FA) corresponds to any recognizable spot on SS-OCTA, and to provide subsequent diagnosis of choroidal neovascularization (CNV) in the course of CSC. Methods: A prospective interventional case series was conducted in a private outpatient office on 30 eyes of 27 patients. In addition to ophthalmic examination, FA, spectral-domain OCT, SS-OCT and SS-

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Wijesingha, Naomi, Wei-Shan Tsai, Ayse Merve Keskin, et al. "Optical Coherence Tomography Angiography as a Diagnostic Tool for Diabetic Retinopathy." Diagnostics 14, no. 3 (2024): 326. http://dx.doi.org/10.3390/diagnostics14030326.

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Diabetic retinopathy (DR) is the most common microvascular complication of diabetes mellitus, leading to visual impairment if left untreated. This review discusses the use of optical coherence tomography angiography (OCTA) as a diagnostic tool for the early detection and management of DR. OCTA is a fast, non-invasive, non-contact test that enables the detailed visualisation of the macular microvasculature in different plexuses. OCTA offers several advantages over fundus fluorescein angiography (FFA), notably offering quantitative data. OCTA is not without limitations, including the requirement

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Kim, Jonghyun, So Min Ahn, Cheolmin Yun, Seong-Woo Kim, and Jaeryung Oh. "Comparison of Indocyanine Green Angiography and Optical Coherence Tomography Angiography for Polypoidal Choroidal Vasculopathy." Journal of the Korean Ophthalmological Society 62, no. 9 (2021): 1198–206. http://dx.doi.org/10.3341/jkos.2021.62.9.1198.

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Purpose: To assess the diagnostic value of optical coherence tomography angiography (OCTA), and the factors affecting the diagnosis of polypoidal choroidal vasculopathy (PCV) by OCTA and indocyanine green angiography (ICGA). Methods: The numbers and area of polyps, and the presence and area of a branched vascular network (BVN) as revealed by ICGA and OCTA, were retrospectively analyzed in 43 patients with active PCV. The patients were divided into two groups according to whether the number of polyps matched between the two methods: group 1, equal number of polyps revealed by ICGA and OCTA; gro

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Lv, Meng, Tuo Li, and Yin Li. "Clinical application of optical coherence tomography angiography in diabetic macular edema." African Health Sciences 23, no. 2 (2023): 484–9. http://dx.doi.org/10.4314/ahs.v23i2.56.

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Diabetic macular edema (DME) is characterized by a retinal thickening or hard exudation deposition in the fundus microvasculature,capillary leakage, increased vascular permeability, extracellular fluid accumulation in the fovea of a foveal disc. Optical coherence tomography angiography (OCTA) is a new item of fundus structure examination. OCTA is to reconstruct the retinal choroidal vascular structure from the continuous same cross-sectional views and blood flow signals obtained by optical scanning, thereby obtaining an image. It is very significant to evaluate, diagnose, treat and manage the

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Obuchowska, Iwona, and Joanna Konopińska. "Importance of Optical Coherence Tomography and Optical Coherence Tomography Angiography in the Imaging and Differentiation of Choroidal Melanoma: A Review." Cancers 14, no. 14 (2022): 3354. http://dx.doi.org/10.3390/cancers14143354.

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Choroidal melanoma requires reliable and precise clinical examination and diagnosis to differentiate it from benign choroidal nevi. To achieve accurate diagnosis, as well as monitoring the progression of disease, various imaging modalities are used, including non-invasive optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). This review begins with a historical account of the development of OCT and OCTA and the methods of generation of images. This outlines the understanding of what OCT/OCTA images show, as well as how image artifacts arise. The anatomy and im

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Schreur, Vivian, Artin Domanian, Bart Liefers, et al. "Morphological and topographical appearance of microaneurysms on optical coherence tomography angiography." British Journal of Ophthalmology 103, no. 5 (2018): 630–35. http://dx.doi.org/10.1136/bjophthalmol-2018-312258.

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AimsTo investigate retinal microaneurysms in patients with diabetic macular oedema (DME) by optical coherence tomography angiography (OCTA) according to their location and morphology in relationship to their clinical properties, leakage on fundus fluorescein angiography (FFA) and retinal thickening on structural OCT.MethodsOCTA and FFA images of 31 eyes of 24 subjects were graded for the presence of microaneurysms. The topographical and morphological appearance of microaneurysms on OCTA was evaluated and classified. For each microaneurysm, the presence of focal leakage on FFA and associated re

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Boned-Murillo, Ana, Henar Albertos-Arranz, María Dolores Diaz-Barreda, et al. "Optical Coherence Tomography Angiography in Diabetic Patients: A Systematic Review." Biomedicines 10, no. 1 (2021): 88. http://dx.doi.org/10.3390/biomedicines10010088.

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Background: Diabetic retinopathy (DR) is the leading cause of legal blindness in the working population in developed countries. Optical coherence tomography (OCT) angiography (OCTA) has risen as an essential tool in the diagnosis and control of diabetic patients, with and without DR, allowing visualisation of the retinal and choroidal microvasculature, their qualitative and quantitative changes, the progression of vascular disease, quantification of ischaemic areas, and the detection of preclinical changes. The aim of this article is to analyse the current applications of OCTA and provide an u

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Gu, Xingwang, Xinyu Zhao, Qing Zhao, Yuelin Wang, and Youxin Chen. "Recent Advances in Imaging Polypoidal Choroidal Vasculopathy with Swept-Source Optical Coherence Tomography Angiography." Diagnostics 13, no. 14 (2023): 2458. http://dx.doi.org/10.3390/diagnostics13142458.

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The gold standard for polypoidal choroidal vasculopathy (PCV) diagnosis is indocyanine green angiography (ICGA), but optical coherence tomography angiography (OCTA) has shown promise for PCV imaging in recent years. However, earlier generations of OCTA technology lacked the diagnostic efficacy to replace ICGA. Swept-source optical coherence tomography angiography (SS-OCTA), the latest generation of OCTA technology, has significantly improved penetrating ability, scanning speed, scanning range, and overall image quality compared with earlier generations of OCTA. SS-OCTA reveals a “tangled vascu

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Ikebukuro, Toyo, Tsutomu Igarashi, Shuhei Kameya, Takeshi Arima, Tomoyuki Kunishige, and Hiroshi Takahashi. "Optical Coherence Tomography Angiography of Nonarteritic Cilioretinal Artery Occlusion Alone." Case Reports in Ophthalmological Medicine 2021 (January 27, 2021): 1–6. http://dx.doi.org/10.1155/2021/8845972.

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Cilioretinal artery occlusion (CLRAO) is a rare disease. Here, we report the case of a 70-year-old man with nonarteritic cilioretinal artery occlusion alone. The patient was allergic to fluorescein. Therefore, we followed the retinal circulation with optical coherence tomography angiography (OCTA). OCTA at 40 days postonset showed partial improvement in the retinal circulation.

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Alibhai, A. Yasin, Mary K. Durbin, Huiyuan Hou, et al. "Clinical Performance of Semi-Automated Spectral-Domain Optical Coherence Tomography Angiography." Journal of Clinical Medicine 13, no. 21 (2024): 6301. http://dx.doi.org/10.3390/jcm13216301.

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Background/Objectives: To evaluate the clinical performance of two optical coherence tomography angiography (OCTA) devices, including a semi-automated device, with respect to image quality and pathology detection, with fluorescein angiography (FA) and indocyanine green angiography (ICGA) serving as the reference standards. Methods: In this prospective cross-sectional study, normal eyes and those with various retinal and choroidal pathologies were enrolled and underwent OCTA scanning using semi-automated 3D OCT-1 Maestro2 and Cirrus™ HD-OCT 5000 devices, as well as FA/ICGA imaging. OCTA scans a

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Ang, Marcus, Kavya Devarajan, Suchandrima Das, et al. "Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation." British Journal of Ophthalmology 102, no. 7 (2017): 873–77. http://dx.doi.org/10.1136/bjophthalmol-2017-311072.

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AimTo newly describe a spectral-domain (SD) optical coherence tomography angiography (OCTA) for the cornea and directly compare two OCTA system scans of the same eyes with corneal vascularisation.MethodsCross-sectional, observational, comparative case series. We performed sequential OCTA scans (10 eyes of 10 subjects with corneal vascularisation,4 scans each eye) repeated using split-spectrum amplitude decorrelation algorithm angiography system (SSADA, AngioVue; Optovue Inc, USA) and SD OCTA (Angioscan; Nidek Co. Ltd, Japan) in the same region of interest. We analysed all scan images for repea

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Bansal, Pooja, and Meenakshi Thakar. "Role of optical coherence tomography angiography in diagnosis and management of inflammatory choroidal neovascular membrane in multifocal choroiditis – A case report." Indian Journal of Ophthalmology - Case Reports 4, no. 1 (2024): 166–69. http://dx.doi.org/10.4103/ijo.ijo_1234_23.

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A 32-year-old male presented with decreased vision in the left eye. Fundus examination revealed healed multifocal choroiditis (MFC) and a juxtafoveal subretinal bleed. Optical coherence tomography (OCT) revealed streak subretinal fluid (SRF) and subretinal hyperreflective material (SHRM) at the macula. Fluorescein angiography (FA) showed a small area of faint hyperfluorescence adjacent to a choroiditis scar, amidst background scarring. Optical coherence tomography angiography (OCTA) detected type 2 choroidal neovascular membrane (CNV). A detailed clinical examination with appropriate ancillary

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