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Relevant bibliographies by topics / Oral homeostasis

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Academic literature on the topic 'Oral homeostasis'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Oral homeostasis"

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Wallet, Shannon. "TLR2 Regulation of Oral Keratinocyte Driven Mucosal Homeostasis in the Context of Diabetes Mellitus (47.11)." Journal of Immunology 184, no. 1_Supplement (2010): 47.11. http://dx.doi.org/10.4049/jimmunol.184.supp.47.11.

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Abstract Oral epithelium contributes to innate immunity and plays an important role in immune tolerance/homeostasis. Disruption of this homeostasis can result in initiation and/or exacerbation of localized inflammation that secondarily causes/worsens systemic diseases. Toll-like receptor 2 (TLR2) is one molecular pattern receptor that under cell- and/or environment-specific conditions can induce either inflammatory or regulatory immune responses. Hyperglycemia, a sequela of diabetes mellitus, has multiple profound effects on the local innate responses, which drives cyclical pathogenesis where

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Tomi Kupka, Tomasz. "Oral homeostasis, kill the microbiome or not?" Journal of Applied Biotechnology & Bioengineering 6, no. 2 (2019): 49–55. http://dx.doi.org/10.15406/jabb.2019.06.00174.

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The objective is to short review the current state of the art of dental antimicrobial agents in term of minimal invasive restorative dentistry. An outline of the most important aspects of dental antimicrobial agents was created, and a subsequent literature search for articles related was conducted. The current state of the art of antimicrobial agents includes a variety of species with broad ranges of properties. There is no agreement as to the choice of substances and concentration, however, there is a growing consensus regarding the need to use antimicrobial agents as additions into dental re

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Cortés-Vieyra, Ricarda, Carlos Rosales, and Eileen Uribe-Querol. "Neutrophil Functions in Periodontal Homeostasis." Journal of Immunology Research 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/1396106.

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Oral tissues are constantly exposed to damage from the mechanical effort of eating and to microorganisms, mostly bacteria. In healthy gingiva tissue remodeling and a balance between bacteria and innate immune cells are maintained. However, excess of bacteria biofilm (plaque) creates an inflammation state that recruits more immune cells, mainly neutrophils to the gingiva. Neutrophils create a barrier for bacteria to reach inside tissues. When neutrophils are insufficient, bacteria thrive causing more inflammation that has been associated with systemic effects on other conditions such as atheros

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Borowiec, Blanka, Sylwia Ciesiółka, Krzysztof Janowicz, et al. "The processes of homeostasis, chemotaxis and organic and inorganic response are significantly up-regulated during short-term oral mucosal cells in vitro cultivation." Medical Journal of Cell Biology 8, no. 1 (2020): 50–59. http://dx.doi.org/10.2478/acb-2020-0006.

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AbstractMucous membranes appear in various parts of the whole body performing similar functions. However, they differ based on where the mucosa is located. It functions as a barrier in such systems as: respiratory, urogenital and digestive . In this study we will be focusing strictly on the oral mucosa. Keratinocytes and fibroblasts, which mainly form the structure of the oral mucosa, are subjected to numerous factors. Being one of the million parts that build the animal organism, they are involved in various processes. In this study, we will try to confirm that in the in vitro culture of oral

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Nassar, Maria, Yaara Tabib, Tal Capucha, et al. "GAS6 is a key homeostatic immunological regulator of host–commensal interactions in the oral mucosa." Proceedings of the National Academy of Sciences 114, no. 3 (2017): E337—E346. http://dx.doi.org/10.1073/pnas.1614926114.

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The oral epithelium contributes to innate immunity and oral mucosal homeostasis, which is critical for preventing local inflammation and the associated adverse systemic conditions. Nevertheless, the mechanisms by which the oral epithelium maintains homeostasis are poorly understood. Here, we studied the role of growth arrest specific 6 (GAS6), a ligand of the TYRO3–AXL–MERTK (TAM) receptor family, in regulating oral mucosal homeostasis. Expression of GAS6 was restricted to the outer layers of the oral epithelium. In contrast to protein S, the other TAM ligand, which was constitutively expresse

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Nagai, Motoyoshi, Takuma Okawa, Kazuaki Nakata, Yuki I. Kawamura, and Koji Hase. "Nutritional factors govern gut homeostasis via oral tolerance." Journal of Immunology 210, no. 1_Supplement (2023): 153.06. http://dx.doi.org/10.4049/jimmunol.210.supp.153.06.

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Abstract Oral tolerance is one of the most critical systems to regulate allergic disorders. However, how dietary factors regulate the induction and maintenance of oral tolerance remains to be elucidated. To address this, we temporarily omitted the food supply by fasting before oral ovalbumin (OVA) administration. We observed that fasting mitigated the expansion of OVA-specific Treg cells. This abnormality mainly resulted from functional defects in CX3CR1 highmacrophages responsible for the uptake of luminal OVA and the reduction of tolerogenic CD103 +dendritic cells (DCs). Eventually, fasting

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Honey, Nafzia, and Niroshini Rajaram. "The Dynamic Role Of Myofibroblasts In Oral Tissue Homeostasis And Disease." International Journal of Histopathological Interpretation 13, no. 1 (2024): 11–16. http://dx.doi.org/10.56501/intjhistopatholinterpret.v13i1.1047.

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Myofibroblasts are specialized cells that play a crucial role in maintaining the structural integrity and function of oral tissues. These cells exhibit a unique phenotype marked by the expression of alpha-smooth muscle actin (α-SMA), and possess the ability to contract and produce extracellular matrix components. In healthy oral tissues, myofibroblasts contribute to tissue homeostasis by mediating wound healing, tissue remodeling, and matrix turnover. However, the dysregulation of myofibroblast function can lead to pathological conditions such as fibrosis, scarring, and oral cancer. This revie

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Wallet, Shannon, Tess Alonso, Charles Lalane, Dana Catalfamo, and Kathleen Neiva. "Altered oral mucosal homeostasis in Type 1 diabetes (162.19)." Journal of Immunology 186, no. 1_Supplement (2011): 162.19. http://dx.doi.org/10.4049/jimmunol.186.supp.162.19.

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Abstract In type 1 diabetes (T1D) alterations in mucosal barrier function and immunity are implicated in disease pathogenesis. We have reported that TLR2-inducing homeostatic responses are disrupted in oral epithelial cells (HOK) from T1D individuals. The objective of the study was to delineate mechanisms of TLR2-induced homeostasis altered in T1D. miRNA, protein phosphorylation and cytokine expression were evaluated in HOK challenged with TLR2 or TLR4 agonists. Expression of cytokines was evaluated using a multiplex assay. Total RNA was probed for miR146a, mir133, miR9 and miR155 using qPCR.

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Mandel, Irwin D. "The role of saliva in maintaining oral homeostasis." Journal of the American Dental Association 119, no. 2 (1989): 298–304. http://dx.doi.org/10.14219/jada.archive.1989.0211.

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Vacek, Jan. "Role of electrophiles in oral cavity redox homeostasis." Free Radical Biology and Medicine 233 (June 2025): S58. https://doi.org/10.1016/j.freeradbiomed.2025.05.204.

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Dissertations / Theses on the topic "Oral homeostasis"

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Hou, Lin. "The distribution and characterization of protease-activated receptors in oral mucosa and skin." Thesis, Queen Mary, University of London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286544.

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Fernandes, Gustavo. "Avaliação do metabolismo glicêmico e perfil entero-hormonal no pós-operatório precose em pacientes abesos graves diabéticos submetidos à gastroplastia em Y de Roux.Comparação da oferta alimentar por via oral e por gastrostomia." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-29112017-091214/.

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INTRODUÇÃO: O diabetes mellitus tipo 2 (DM2) é uma doença correlacionada com a obesidade mórbida. O paciente obeso apresenta efeito incretínico suprimido e consequente desbalanço da homeostase glicêmica. Diversos estudos evidenciam a melhora do DM2 após a confecção da Gastroplastia com derivação intestinal em Y de Roux (GDYR). Os mecanismos de controle da glicemia podem ser de longo e curto prazo. Os mecanismos de ação precoce estão ligados à restrição calorica, melhora da resistência insulínica, da função da célula beta pancreática e retorno do efeito incretínico pelo aumento do GLP1 e GIP, p

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Daba, Alina. "Insights on systemic and cellular iron homeostasis: hepcidin responses to oral and parenteral iron loading and an alternative mechanism for ferritin mRNA translation." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107735.

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Iron is vital for all living organisms, but due to its ability to readily accept or donate electrons, it is also potentially toxic. Finely tuned mechanisms have evolved to control iron homeostasis at the systemic and cellular level. The peptide hormone hepcidin controls systemic iron homeostasis by binding to and degrading the iron exporter, ferroportin, leading to decreased iron efflux from duodenal enterocytes, macrophages and hepatocytes into the blood stream. Cellular iron homeostasis is regulated by the IRE / IRP system, which controls the levels of proteins involved in iron uptake, utili

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Moro-Sibilot, Ludovic. "Contribution du foie et des cellules dendritiques plasmacytoïdes dans la réponse humorale à Immunoglobines A." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10207/document.

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La réponse humorale à immunoglobulines A (IgA) constitue un des principaux mécanismes immunologiques permettant de maintenir l'homéostasie intestinale. L'initiation de la réponse IgA se déroule dans les tissus lymphoides associés à l'intestin, où la reconnaissance des antigènes intestinaux entraine l'activation des lymphocytes B naïfs, la commutation isotypique vers IgA et leur différenciation en plasmocytes. Mon travail de thèse a consisté à étudier la contribution du foie et des cellules dendritiques plasmacytoides (pDC) dans la réponse IgA intestinale. L'utilisation de deux modèles murins p

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Folia, Mireille. "Xéno-hormones et homéostasie buccale : impact sur les perceptions gustatives et les glandes salivaires." Phd thesis, Université de Bourgogne, 2012. http://tel.archives-ouvertes.fr/tel-00905906.

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L'homéostasie buccale conditionne fortement les perceptions gustatives ; elle repose sur un épithélium buccal sain et le bon fonctionnement des glandes salivaires, qui sont finement régulés par hormones sexuelles. Le but de cette thèse était de savoir si une exposition orale en bisphénol A, un migrant d'emballage alimentaire et de composites dentaires, et une alimentation riche en phyto-œstrogènes (soja) pouvaient modifier l'homéostasie buccale. Deux expérimentations ont été conduites : une étude dose-effet du BPA (5µg à 12,5 mg/kj/j) chez le rat adulte, et une étude d'interaction d'un régime

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Ku, Shih Ming, and 施明谷. "The effect of eight weeks oral CLA supplementation on glucose homeostasis and inulin action in health humans." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/86418636457312175909.

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碩士<br>國立臺中教育大學<br>體育學系碩士班<br>102<br>Conjugated linoleic acid (CLA) is a compound that contains eighteen carbons and unsaturated fatty acids with two double bonds. CLA has been shown to enhance the fatty acid oxidation and reduce the body fat in animal studies. However, there were adverse effects on glucose uptake were found in obese human studies. Little study was found regarding to whether short term CLA administration is expected to influence glucose homeostasis and reducing insulin action in health humans. Therefore, the present study was to examined that effect of eight weeks oral CLA sup

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Fang, Yi-chien, and 方譯謙. "The effect of m-3m3FBS and paroxetine on calcium homeostasis and viability in OC2 human oral cancer cells and canine MDCK renal tubular cells." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/42156932706578790146.

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博士<br>國立中山大學<br>生物科學系研究所<br>99<br>The effect of 2,4,6-trimethyl-N-(meta-3-trifluoromethyl-phenyl)- benzenesulfonamide (m-3M3FBS), a presumed phospholipase C activator, on cytosolic free Ca2+ concentrations ([Ca2+]i) in Madin Darby canine kidney (MDCK) cells and OC2 human oral cancer cells was unclear. This study explored whether m-3M3FBS changed basal [Ca2+]i levels in suspended MDCK and OC2 cells by using fura-2 as a Ca2+-sensitive fluorescent dye. m-3M3FBS at concentrations between 0.1-20 μM increased [Ca2+]i in a concentration-dependent manner in MDCK cells, however in OC2 cells, m-3M3FBS a

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Books on the topic "Oral homeostasis"

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Goldberg, Elizabeth Mariel. The role of NSD1 in oral squamous homeostasis and HNSCC tumorigenesis. [publisher not identified], 2022.

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institutet, Karolinska, ed. Oral rehydration therapy in infectious diarrhoea: Studies of fluid and electrolyte homeostasis. Kongl Carolinska Medico Chirurgiska Institutet, 1987.

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Marples, David, and Søren Nielsen. Water homeostasis. Edited by Robert Unwin. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0022_update_001.

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Under normal circumstances, the maintenance of water balance is a question of balancing urine output against oral water intake, after allowance for the largely unregulated loss of water through other routes (respiratory, transcutaneous, and via the gastrointestinal tract). Normally, this is managed by the feedback mechanisms controlling thirst and diuresis, but in a medical context it is important to allow for other forms of administration that may not be under the control of the patient, and other routes of fluid loss, such as haemorrhage and drains. Electrolyte and water homeostasis are clos

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Gilchrist, Francis J., and Alex Horsley. Management of respiratory exacerbations. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198702948.003.0005.

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Cystic fibrosis lung disease is characterized by chronic infection, inflammation and a progressive loss of lung function. Patients are also affected by recurrent episodes of increased respiratory symptoms, called exacerbations which have a detrimental effect on quality of life, the rate of lung function decline, and mortality. Early diagnosis and treatment is vital. Diagnosis relies on a combination of symptoms, examination findings, the results of laboratory tests, and lung function. Antibiotics are the mainstay of treatment but airway clearance, nutrition, and glucose homeostasis must also b

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Book chapters on the topic "Oral homeostasis"

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Allam, Jean-Pierre, and Natalija Novak. "Mucosal Homeostasis of the Oral Mucosa." In Oral Mucosa in Health and Disease. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-56065-6_5.

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Fredman, Gabrielle, and Charles N. Serhan. "Specialized Pro-Resolving Lipid Derived Fatty Acid Mediators: Wiring the Circuitry of Effector Immune Homeostasis." In Oral Wound Healing. John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118704509.ch4.

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Moorthy, Aditya, and Shreya Krishna. "Management of Medical Comorbidities in Maxillofacial Surgery." In Oral and Maxillofacial Surgery for the Clinician. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_3.

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AbstractOral and Maxillofacial surgery, like any surgical specialty, has two vital requirements. First, having the right armamentarium, and, second, acquiring appropriate skills and knowledge of the patients’ disease process, including comorbidities. With the changing demographic in India, the profile of Indian patient has undergone a sea change in the last few decades. From acute conditions that had little impact on subsequent health of the patient, we have arrived at a scenario where a large proportion of patients present with chronic disorders like diabetes, ischemic heart diseases, etc. th

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de Barros Santos, Heitor Sales, Maria Eduarda Lisbôa Pagnussatti, and Rodrigo Alex Arthur. "Symbiosis Between the Oral Microbiome and the Human Host: Microbial Homeostasis and Stability of the Host." In Advances in Experimental Medicine and Biology. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-79146-8_3.

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Zhou, B., L. Yan, X. Wang, I. Schoenmakers, G. R. Goldberg, and A. Prentice. "Seasonal Differences in Mineral Homeostasis and Bone Metabolism in Response to Oral Phosphate Loading in Older Northern Chinese Adults." In Nutritional Influences on Bone Health. Springer London, 2010. http://dx.doi.org/10.1007/978-1-84882-978-7_13.

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Ecesoy, Volkan, and Hasan Arici. "Evaluation of Diabetes and Biochemical Markers." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.4.

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The evaluation of diabetes through biochemical markers involves a comprehensive approach to assess metabolic disturbances and monitor disease progression. Key biochemical markers include blood glucose levels, glycosylated hemoglobin (HbA1c), and insulin sensitivity indices such as the homeostatic model assessment of insulin resistance (HOMA-IR). Blood glucose levels are fundamental for diagnosing and managing diabetes, with fasting plasma glucose and oral glucose tolerance tests providing insights into glycemic control. HbA1c, reflecting average blood glucose levels over the preceding 2-3 mont

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Yasunaga, Madoka, Masahiro Yamaguchi, Kei Seno, Mizuki Yoshida, and Jun Ohno. "Role of autophagy in dysregulation of oral mucosal homeostasis." In Inflammation and Oral Cancer. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-323-88526-3.00006-3.

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Başeğmez, Mehmet. "Management of Parenteral and Oral Vitamin C Supplementation for Vitamin C Homeostasis in the Organism: A Narrative Review." In Recent Studies on Vitaminology - Insights, Applications and Uses [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1006708.

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The review aimed to determine the possible positive or negative effects of oral or parenteral vitamin C supplementation on homeostasis processes in the organism. Vitamin C is commonly used in different sectors, such as cosmetics and raw materials, especially in the food and beverage sector. In addition, individual use of vitamin C supplements has increased in recent years, especially for disease prevention and alleviation. This led to individuals consuming excessive amounts of easily accessible vitamin C. As a result, vitamin C supplements are known to be safe for physiological systems, but hi

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Valdés Rubio, Enrique. "Impact of the Use of Metformin in the Prevention of Gestational Diabetes Mellitus in the High-Risk Population: An Article Review." In Glucose and Insulin Homeostasis. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1006121.

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Gestational diabetes mellitus (GDM) is a condition characterized by a carbohydrate metabolism disorder of variable severity. The onset or first detection occurs during pregnancy. Its prevalence has increased dramatically in the last 10 years. Etiological factors that make these pregnant women a population at a high risk of developing GDM include maternal obesity, increase in maternal age, family history of diabetes mellitus, polycystic ovary (PCOS) and pregestational insulin resistance (PIR). The impact of metformin (MET), a second-generation insulin-sensitizing biguanide, on the prevention tr

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Longridge, Nicholas, Pete Clarke, Raheel Aftab, and Tariq Ali. "Oral Medicine and Oral Pathology." In Oxford Assess and Progress: Clinical Dentistry, edited by Katharine Boursicot and David Sales. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198825173.003.0019.

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The mouth has often been looked at as a window into the body, and this is no truer than in oral medicine. The oral mucosa is a highly adapted and robust tissue, which, at the same time, can be very susceptible to changes in homeostasis. Dysregulation of the immune system, alterations in cellular signalling pathways, or insult from exogenous stimuli can lead to an array of weird and wonderful oral lesions. Clinicians today are likely to see changes to the oral mucosa on a regular basis— from common ulcers, bony lumps, or white patches to more exotic pigmented lesions or unusual lumps. It is th

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Conference papers on the topic "Oral homeostasis"

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Shimonosono, Masataka, Takashi Kijima, Hisatsugu Maekawa, et al. "Abstract 501: Aldh2 mutation promotes oral and esophageal cancer stem cells via autophagy-mediated redox homeostasis." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-501.

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Farah, Huda Mohamed, Muram Elmubarak Elamin, Rahaf Nader Nader Nader, et al. "Metagenomic Analysis of Oral Microbiome during pregnancy." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0135.

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Pregnancy is a dynamic physiological process associated with significant hormonal, immune and metabolic changes to support the growth and development of the fetus. Several studies have highlighted the role of gut microbiota during pregnancy1. The composition of gut microbiota changes dramatically during the course of pregnancy with an increase in Proteobacteria and Actinobacteria, a decline in butyrate-producing bacteria and a reduction in bacterial richness at the end of pregnancy2. These modifications were anticipated to favour the increased metabolic demand during pregnancy, which will, in

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Ayoub, Dibe Balardini. "BASES ORIGINÁRIAS DAS NEOPLASIAS HEMATOLÓGICAS." In II Congresso Brasileiro de Hematologia Clínico-laboratorial On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/hematoclil/37.

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Introdução: A compreensão das bases originárias de neoplasias hematológicas é imprescindível para o combate a leucemias, linfomas e síndromes mielodisplásicas. Nesse viés, percebe-se a importância do estudo acerca dessas bases, isto é, os genes envolvidos, a fim de possivelmente identificá-los e impedir que gerem a proliferação de neoplasias desse caráter. Objetivos: O presente estudo tem por objetivo principal apresentar bases teóricas, a nível molecular, para o entendimento daquilo que se configura como uma neoplasia hematológica. Tornando assim possível a consolidação do conhecimento acerca

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Guirão, AB, VAB Garcia, NO Nacaguma, LFA Nery, CM Araujo, and BO Barreto. "ANÁLISE DE VITAMINA D EM INDIVÍDUOS NA FAIXA ETÁRIA DE 0 A 15 ANOS." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.6677.

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Objetivo: Avaliar o déficit de vitamina D em pacientes jovens, tendo como referência um laboratório clínico em São Caetano do Sul. A vitamina D é considerada um pré-hormônio e apresenta papel crucial na homeostase do cálcio e, consequentemente, na saúde óssea. A maior fonte de vitamina D é a pele, em resposta à luz solar. São encontradas apenas pequenas quantidades dessa vitamina em alguns alimentos (especialmente peixes gordurosos), o que faz com que a disponibilidade da vitamina D na dieta seja limitada. Estudos populacionais brasileiros demonstram que a prevalência da hipovitaminose D no no

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Balbueno, Melina Castilho de Souza, Jéssica Amancio Martins, and Cidéli de Paula Coelho. "TRATAMENTO COM MEDICAMENTOS DE ALTAS DILUIÇÕES EM CADELA COM PIOMETRA: RELATO DE CASO." In I Congresso On-line Nacional de Clínica Veterinária de Pequenos Animais. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/2399.

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Introdução: Piometra é caracterizada por infecção bacteriana aguda ou crônica, com acúmulo de exsudato em lúmen uterino e é um diagnóstico muito comum em cadelas não castradas, especialmente em fase de meia idade e mais velhas. O principal tratamento recomendado é a ovariohisterectomia, por ser o método mais seguro e eficaz e em alguns casos o tratamento médico é uma alternativa. A homeopatia visa a homeostase do paciente, ou seja, o equilíbrio. Seu efeito benéfico, sem efeitos colaterais é visualizado em diversos estudos com animais, assim como estudos in vitro. Objetivo: O presente trabalho

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Kelly Mucarbel dos Santos, Alicia, Karollainy Vasconcelos Cavalcanti, Lucas Valeriano Marques, Raquel Desenzi Pessoa, Renata de Barros Ferraz, and Alydyanny Waleska Rodrigues de Araújo Cavalcanti. "Injúria renal aguda em cães e gatos." In Congresso Online Acadêmico de Medicina Veterinária. Congresse.me, 2022. http://dx.doi.org/10.54265/tdsa2115.

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Introdução: A Injúria Renal Aguda (IRA) é uma síndrome bastante recorrente na clínica de cães e gatos, sendo definida como uma perda de função renal que ocorre subitamente e que pode ter uma duração indeterminada. Cães e gatos que desenvolvem a injúria renal aguda tem como consequência distúrbio hidroeletrolítico, ácido base, uremia e hipertensão. Essas alterações se dão devido à perda de função renal que é responsável por manter a homeostasia hidroeletrolítrica do animal e excretar substâncias nocivas ao organismo. O diagnóstico da IRA se fundamenta no exame físico do paciente, sendo bastante

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