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Dissertations / Theses on the topic 'Osteoarthritis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kiser, Connie Hutley. "Impact of Osteoarthritis Self-Efficacy Toolkit on Adults with Osteoarthritis." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3617.

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Over 26 million U.S. citizens have a form of arthritis; osteoarthritis (OA) is the most common form. Self-efficacy (SE) is defined as a psychological construct which identifies an individual's confidence when performing a behavior. SE is deemed a vital judge of self-management (SM) in those with OA. The purpose of this evidence-based practice, quality improvement project was to improve SE in OA patients. The identified gap in nursing practice was the lack of SE in OA patients. The project question asked whether a toolkit with information regarding SE in OA can improve SE of management of disea

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2

Farrán, Díaz-Cano Aina. "Pathophysiology of osteoarthritis." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/456376.

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Osteoarthritis (OA) is a multifactorial disease characterized by a progressive degeneration and eventual failure of the synovial joint functionality. Although it has been traditionally considered as an exclusive disease of the articular cartilage, nowadays it is considered as a whole joint disease. Therefore, the progression of the disease involves articular cartilage degeneration, osteochondral bone sclerosis and synovial membrane hypertrophy. Articular cartilage is a connective tissue resistant to tensile and shears strength that is composed of water (>70%) and a dense extracellular matrix (

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3

Pengas, Ioannis. "Meniscectomy & osteoarthritis." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/967af95f-c162-4870-9b4d-7e0287ebf1a2.

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Meniscal tears are the commonest knee injury and currently are addressed almost exclusively by arthroscopy. Ian Smillie the late Professor of orthopaedics in Tayside, popularised open total meniscectomy worldwide during the 1950s believing that this was necessary for a functioning fibrocartilage replica to completely occupy the ensuing space. The cohort in this study underwent open total meniscectomy under his care prior to their 19th birthday. It was documented in their then records that no other knee pathology was observed during the operation and that the same post operative regime was foll

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4

Vanhook, Patricia M., Lynne M. Dunphy, T. South, L. Plank, and C. Luskin. "Osteoarthritis and Osteoporosis." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7411.

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Book Summary: Serves the needs of advanced practice nurses because it’s written by nurse practitioners for nurse practitioners, in collaboration with a physician. Organizes content around the Circle of Caring framework for nursing-based knowledge and holistic care. Explores complementary and alternative treatments for each disorder. Covers the broadest range of human disease and disorders using a systems-based approach, presenting both common complaints and common problems to help students narrow down the possible differentials to the most likely diagnosis. Considers interactions of pharmace

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5

Lim, Keith K. T. "Osteoarthritis of the hand." Thesis, University of Bristol, 1997. http://hdl.handle.net/1983/3282d842-4e4d-4db9-9dd4-1542cf8aefc9.

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6

Dahlberg, Leif. "Post-traumatic arthrosis cartilage markers in joint fluid for the identification of patients at risk /." Lund : Dept. of Orthopaedics, University Hospital, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39854555.html.

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7

Morley, Gavin W. "Gene hunting in primary osteoarthritis." Thesis, University of Oxford, 2004. https://ora.ox.ac.uk/objects/uuid:1529aa12-2d57-48fd-8cb9-a5bab0291116.

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Osteoarthritis (OA) is a common, disabling disease of the elderly. It is uncommon in individuals under 45 years of age, and prevalence is higher in females than males. OA is characterised by focal cartilage loss accompanied by osteophytes, sclerosis and often some inflammatory response. A significant genetic component to OA has been demonstrated by twin-pair, sibling risk and segregation studies. Our group previously carried out a two-stage genome-wide linkage scan and identified six chromosomal regions as potentially harbouring OA susceptibility genes. The aim of this project was to examine t

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8

Palmer, Antony. "Aspects of early hip osteoarthritis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:f2d4b3b0-24b4-4053-86fe-97637cebf37d.

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Osteoarthritis develops secondary to the action of hostile biomechanics upon susceptible cartilage. Cam morphology describes a loss of concavity at the femoral head-neck junction resulting in femoral impaction against the acetabular rim within a functional range of movement. This impaction is termed femoroacetabular impingement and can result in pain and cause damage to adjacent articular cartilage that progresses to osteoarthritis. Cam morphology is a target for joint preservation strategies. The first study in this thesis compares hip development in academy football players with controls fro

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9

Ratzlaff, Charles R. "Lifetime physical activity and osteoarthritis." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36735.

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Introduction: The overall goal of this thesis is to improve understanding of physical activity (PA), one of the most important, modifiable but controversial risk factors in osteoarthritis (OA). OA is the major public health problem in musculoskeletal medicine and leading cause of physical disability in older adults. The ultimate purpose is to provide evidence to inform OA prevention strategies, something not currently available. Objectives: 1) To construct and describe lifetime trajectories of hip and knee joint force from physical activity in a large Canadian sample; 2) To validate self-repor

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10

Chard, Jiri Alexander. "Investigation of services for osteoarthritis." Thesis, University of Bristol, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437311.

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11

Soni, Anushka. "Pain characterisation in knee osteoarthritis." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:4026d694-8e7b-47f5-9f05-9f5a7b2165a0.

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Osteoarthritis (OA) is the most common form of arthritis in the world, and it has been estimated that about one tenth of the world's population, aged over 60, have symptoms that can be attributed to OA. Despite the size of the global impact of OA, there is a significant unmet need for effective treatments. Knee replacement surgery is commonly used in patients with moderate to severe knee OA, in order to reduce pain. However, 10-34% of patients report an unfavourable long-term outcome with persistent pain after surgery. The neural mechanisms for the generation of pain in knee OA are not fully u

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12

Budd, Emma. "MicroRNAs in osteoarthritis and chondrogenesis." Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/407447/.

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Loss of chondrocytes along with diminishment of specialised extracellular matrix (ECM) is often the outcome of articular cartilage injury and can progress to the onset of osteoarthritis (OA). OA is typically seen as an age related disease and with the changing world demographic, the fastest growing age category is the elderly population. Cartilage injury, which may result in OA, results in the clinical requirement for replacement of degenerated tissues and with an ageing population the demand for clinical replacement of degenerated tissue is set to dramatically increase posing socio-economic b

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13

Fox, Beth Anne, Evan D. Schmitz, and Rick L. Wallace. "Glucosamine and Chondroitin for Osteoarthritis." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/8684.

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14

Riordan, Edward A. "Imaging markers for osteoarthritis progression." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20347.

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Joint damage in osteoarthritis (OA) involves characteristic changes in multiple joint tissue types, with alterations in the shape of subchondral bone and composition of synovial fluid occurring concomitantly with cartilage damage. Systemic risk factors such as obesity and local biomechanical processes that determine joint loading have long been shown to predispose to the disease, and more recent evidence suggests that specific genetic loci and inflammatory processes may make contributions, but the exact mechanisms driving the initiation and progression of the disease are yet to be elucidated.

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15

Brismar, Harald. "Morphological and molecular changes in developing guinea pig osteoarthritis /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-456-9/.

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16

Schmitt, Laura Clare. "Knee stabilization and medial knee osteoarthritis." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 0.80 Mb., 201 p, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3220738.

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17

Ishiguro, Naoki, Toshihisa Kojima, and A. Robin Poole. "Mechanism of cartilage destruction in osteoarthritis." Nagoya University School of Medicine, 2002. http://hdl.handle.net/2237/5380.

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18

Clements, Dylan Neil. "The Genetic Basis of Canine Osteoarthritis." Thesis, University of Liverpool, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485910.

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Osteoarthritis (OA) is a common debilitating disease ofmammalian joints. Canine OA was classically understood to arise secondary to articular diseases, such as elbow dysplasia, hip dysplasia and cranial cruciate ligament rupture which produced a mechanical dYllfunction of the affected joint. However it is now recognised that primary factors, such as genetics, govern the severity ofOA for a given articular disease. In this study, two different aspects ofthe genetic basis to OA were investigated; gene transcription in diseased tissues and gene polymorphism frequencies in populations of dogs with

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19

Thomas, Geraint Emyr Rhys. "The patho-aetiology of hip osteoarthritis." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:b4594f27-46ad-47d6-81f1-11ed934e1495.

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Osteoarthritis of the hip frequently occurs in the absence of osteoarthritis in other large joints, suggesting that local factors are important in its pathogenesis. Hip morphology has been recognised as a potential local biomechanical risk factor for the development of hip osteoarthritis. There are no adequate studies examining osteoarthritis development in the hip. Historical cohorts are either limited by a short follow up or by small numbers. This thesis explores the natural history of hip osteoarthritis in a large population cohort with particular attention to hip morphology as a predictor

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20

Paegle, Diana. "Osteoarthritis in temporomandibular joint : internal derangement /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-864-5/.

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21

Abdul-Rahim, Hunar Attoof. "Morphological risk factors in hip osteoarthritis." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606376.

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Purpose: Variation in morphology in the proximal femur and pelvis (e.g. acetabular dysplasia, non-spherical femoral head) can biomechanically compromise the hip joint and predispose to hip osteoarthritis (OA). Such morphological variation may in part explain the heritability of hip OA. The objective of this study was to evaluate a range of 2-dimensional morphological measures on standard radiographs to determine: normal range, right: left symmetry, age and gender differences; and to investigate whether they are associated with the risk of hip OA. Methods: A nested case control study was undert

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22

Stanton, Craig. "Mechanosensitive ion channels in osteoarthritis pain." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121326.

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Osteoarthritis (OA) is a debilitating disease affecting nearly 5 million of Canadians, with aneconomic impact of over $30 billion each year in direct and indirect costs. Pain is the prominent symptom of OA, yet its underlying mechanisms are not completely understood, leading to a lack of effective pain therapies. OA pain is manifested by a hypersensitivity to mechanical stimuli such as joint movement or palpation. Although the mechanical sensitization of pain-sensing nerve fibers, known as nociceptors, innervating the joint has been documented, the molecular and cellular mechanisms underlying

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23

Brown, Sharon Julie. "Studies in cancellous bone in osteoarthritis." Thesis, University of Chester, 2002. http://hdl.handle.net/10034/71237.

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Osteoarthritis (OA) is a common musculoskeletal disability and represents a major health burden to society. Pathological changes are found in all tissues of the joint; however studies on bone are few. The aims of this thesis were to characterize some of the densitometric, mechanical and compositional properties of cancellous bone from the Superior (Sup) and Inferior (Inf) regions of human femoral heads, and to compare age-selected healthy bones with those from patients with end-stage OA. From coronal sections of the femoral head, bone cores were drilled out along the anterior-posterior axis an

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24

Plumb, Amanda Suzanne. "Mechanical and metabolic factors in osteoarthritis." Thesis, University of Aberdeen, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430055.

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<p class=MsoNormal>This study determined the response of elderly human articular cartilage explants to static, cyclic or absence of mechanical load, with or without the addition of the maintenance factor IGF-1. It revealed that elderly human articular cartilage does not behave in the same way as young animal tissue, with cyclic and static loading both causing an inhibition in matrix biosynthesis. In addition, cyclic mechanical load appears to block the effects of IGF-1 in elderly human tissue, in contrast to bovine tissue in which the effects were additive. Osteoarthritic bone was found to

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25

Innes, John Francis. "Osteoarthritis of the canine stifle joint." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361105.

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26

Webb, Ginette Rachel. "Cytokines and cytokine receptors in osteoarthritis." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388158.

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27

Metcalfe, Andrew John. "Knee osteoarthritis is a bilateral disease." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/67638/.

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Knee osteoarthritis (OA) is a common cause of pain and disability. Patients often complain that they overload the other limb when they walk, resulting in disease in the unaffected knee. However, it is unknown whether this happens or the mechanism by which it occurs. Data was analysed from an established longitudinal cohort study to examine the development of bilateral knee OA. One hundred and forty-three subjects were examined over a 12 year period with bilateral radiographs. Bilateral knee osteoarthritis was found to be very common over time, and the majority of individuals with unilateral kn

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28

Driscoll, Clare. "Pathogenesis of pain in murine osteoarthritis." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/25050.

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Pain is the foremost clinical symptom of osteoarthritis (OA), however the processes that lead to pain in the joint are poorly understood. I have used two different murine models of OA, induced by surgical destabilisation of the joint. Upon destabilisation, two episodes of painful behaviour are observed, an initial post-operative phase, lasting a few days, and a late phase that starts between 8-11 weeks post-surgery, detected by differences in weight bearing measured by the Linton incapacitance tester. The later phase is associated with significant cartilage damage, but no overt synovitis. A sc

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29

Harasymowicz, Natalia Sara. "Role of severe obesity in osteoarthritis." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22930.

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Osteoarthritis (OA) is the most common degenerative joint disease affecting more than 40% of people above the age of 65 (Neogi et al., 2013). Obesity is one of the main risk factors of OA and has become a major problem in Western societies. With sedentary lifestyle and the aging of the population, it is estimated that more than 50% of British adults will be obese in 2030 (Wang et al., 2011). So far, the effect of obesity on joint degeneration has primarily been explained by the increased load on the joints. However, a growing number of studies have revealed that adipose tissue can affect carti

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30

Smith, Stephanie L. "Neuromuscular control in knee osteoarthritis (NEKO)." Thesis, Glasgow Caledonian University, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726764.

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31

Chen, Ying-Chun. "Exploring mechano-structural processes in osteoarthritis." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:a802e0a6-f656-4e89-9f3f-0169761607a0.

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Articular cartilage is a remarkable tissue with mechanical performance that surpasses engineering standards. Collagen, the most abundant protein in cartilage, plays an important role in this performance. Building on observations of collagen structural changes at the earliest stages of osteoarthritis, we here explore the role of collagen in the disease process. Specifically, we focus on the material properties and organization of collagen fibrils in the cartilage surface, seeking to answer three key questions: • What are the physical changes to collagen in early osteoarthritis? • How

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32

Fuller, Catherine Jane. "Measures of osteoarthritis in the horse." Thesis, University of Bristol, 1998. http://hdl.handle.net/1983/377e5156-d9f7-4cac-8505-ec56af2a70dd.

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33

Leaver, Roy. "Osteoarthritis and ultra-distance marathon running." Master's thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/26670.

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Osteoarthritis (OA) is the most common degenerative joint disease. The impact loading on the articular cartilage of the large weight bearing joints (hip, knee, and ankle joints) during distance running might be a potential precipitating factor in OA. The aim of this case-control study was to investigate the relationship between total accumulated running volume and OA in the weightbearing joints. In this study, OA was defined as pain and/or stiffness and/or swelling in the weight-bearing and non-weight-bearing joints (wrists and fingers). The subjects for this study were selected from previous

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34

Raine, Emma Victoria Angela. "Expression analysis of osteoarthritis susceptibility loci." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2753.

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Osteoarthritis (OA) is a common disease characterised by the progressive loss of the articular cartilage of synovial joints. It is multifactorial and polygenic. Candidate genebased association studies and genome-wide association scans (GWAS) have been used to identify OA risk alleles with over 10 regions of the human genome so far reported as harbouring OA susceptibility. Expression quantitative trait loci (eQTLs) demonstrate a correlation between gene expression levels and DNA polymorphism, the assumption being that the polymorphism resides within a regulatory element of the gene. The functio

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35

Khoynezhad, Shirin. "Halofuginone Prevents the Progression of Osteoarthritis." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17331948.

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Background: Halofuginone (HF) is a natural product that has been shown to have therapeutic benefits in a variety of pathologic conditions, from cancer to autoimmune diseases. These beneficial effects are mainly through inhibition of pro-inflammatory cytokines. Inflammatory cytokines have been recently shown to exert a crucial role in development of osteoarthritis and one of their most important targets is Matrix metallopeptidase-13 (MMP-13). In this preclinical study, we investigated the effect of HF on the progression of Osteoarthritis. Methods: The effect of adding HF ± IL-1β/TNF-α on mRNA

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36

Woods, Robert Jeffrey. "Biomechanics and osteoarthritis of the knee." Connect to resource, 1995. http://rave.ohiolink.edu/etdc/view.cgi?acc%5Fnum=osu1262616270.

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37

Haemer, Joseph Michael. "Mechanical etiology of osteoarthritis after meniscectomy /." May be available electronically:, 2009. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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38

Sigrist, Nadja E. "Nitric oxide production in canine osteoarthritis /." [S.l.] : [s.n.], 1998. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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39

Duong, Vicky. "Adherence to core treatments in osteoarthritis." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29618.

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Osteoarthritis (OA) is a prevalent and disabling joint condition. Despite numerous treatments for OA, the clinical benefits of core treatments such as exercise remain modest. Adherence (the extent to which treatments have been completed as prescribed) is an important factor influencing outcomes in OA. However, understanding of adherence remains poor. This thesis aims to investigate adherence to core treatments for OA. Chapter One provides a background of OA and presents a narrative review of adherence. Chapter Two presents a systematic review of adherence measures of core treatments in knee

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40

Monteiro, Susana Oliveira Serrano. "Distal limb osteoarthritis in the horse." Doctoral thesis, Universidade de Évora, 2016. http://hdl.handle.net/10174/18560.

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The aim of this thesis was to study two objective methods of osteoarthritis (OA) diagnosis in horses and use them on the assessment of new intra-articular treatments. The studied methods were a new inertial-sensor based system of lameness detection and cartilage biomarkers in serum. It was found that distal limb flexion is significantly correlated to the presence of metacarpo-phalangeal OA in hind limbs and that inertial-sensors are sensitive in detecting asymmetry in these cases. A positive and significant correlation was observed between Coll2-1 concentration in serum and the presence of joi

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41

Intekhab, Alam Nabila Yasmin. "Mechanism of chondrocyte death in osteoarthritis." Thesis, University of Westminster, 2006. https://westminsterresearch.westminster.ac.uk/item/925ww/mechanism-of-chondrocyte-death-in-osteoarthritis.

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42

Tumkur, Jaiprakash Anjali. "Phenotypical changes of osteocytes in osteoarthritis." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/79552/1/Anjali_Tumkur%20Jaiprakash_Thesis.pdf.

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This thesis focuses on the role of a bone cell, osteocytes in the progression of osteoarthritis. The biological relevance of this study has opened doors to new possibilities of understanding the pathogenesis of osteoarthritis.

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Farnaghi, Saba. "Role of hypercholesterolemia in osteoarthritis development." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/103634/1/Saba_Farnaghi_Thesis.pdf.

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Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder associated with mechanical stress and aging but also a ‘metabolic syndrome’ in which several risk factors work together to contribute to disease initiation and/or development. One such metabolic risk factor could be high cholesterol levels in the body. Even though high cholesterol level is a well-known risk factor for cardiovascular disorders, its possible role in musculoskeletal diseases, particularly OA, is not clear. The authors discuss the fundamental viewpoints on cholesterol involvement in the pathog

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Bosser, Catherine. "Biomarqueurs de l'arthrose : analyse tribologique et microspectroscopie Raman du liquide synovial." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSEC046.

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L’arthrose est la plus commune des maladies articulaires dans le monde. Elle induit des charges physiques, psychologiques, sociétales et économiques majeures. Selon les Nations Unies, en 2050, 315 millions de personnes souffriront d’arthrose symptomatique et 105 millions d’entre elles seront fortement handicapées par la maladie.Les symptômes cliniques et les techniques d’imagerie constituent les éléments principaux pour le diagnostic et le suivi de l’arthrose aujourd’hui. En dépit de progrès technologiques et des recherches intensives de nouveaux biomarqueurs, aucun outil ne permet de détecter

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45

Romer, Charlene M. "Stress and coping in older women with osteoarthritis : a qualitative study /." free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9946291.

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46

Krishnasamy, Priathashini. "The Role of Skeletal Muscle in the Incidence and Progression of Knee Osteoarthritis." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20699.

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Skeletal muscle quality may play a role in skeletal muscle health affecting its response to muscle strengthening exercises and susceptibility to osteoarthritis (OA). Chapter One of this thesis provides an introduction to the role of skeletal muscle in the incidence, progression and exercise management of knee OA. Chapter Two examines skeletal muscle quality (muscle attenuation and lean muscle volume), knee extensor strength and percentage whole-body fat as mediators in the symptomatic and functional improvements achieved in a diet and exercise (D+E) compared to D (diet) or E (exercise) interv

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Burks, Kathryn J. "Self-management of osteoarthritis : an intervention study /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3012952.

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48

Kämäräinen, O. P. (Olli-Pekka). "The search for susceptibility genes in osteoarthritis." Doctoral thesis, University of Oulu, 2009. http://urn.fi/urn:isbn:9789514291449.

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Abstract This work engaged Finnish females affected with osteoarthritis (OA) of the hand to define the role of common sequence variations within the genes of the important structural protein of cartilage, aggrecan (AGC1), and the genes of inflammatory mediators, the interleukin 1 gene cluster and interleukin 6 (IL6), as possible risk factors for the disease. Also, a genome-wide linkage analysis was performed in a sample consisting of Finnish families with multiple individuals affected with hip and knee OA in order to reveal new chromosomal areas that are likely to contain disease associated va

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49

Chernos, Michael Benjamin. "A rheological study of treatments for osteoarthritis." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58334.

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Osteoarthritis is a common joint disease causing pain and inflammation that limits mobility and functionality. Osteoarthritis is a widespread disease, and despite it's prevalence there is no cure. The disease progresses by degrading joint cartilage and synovial fluid. The current work aims to contribute to existing knowledge regarding osteoarthritis through three research projects including a rheological study of novel anti-inflammatory hyaluronic acid derivatives, a case study on the effects of oral glucosamine supplementation on synovial fluid viscosity, and development of a microfluidic rhe

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Macri, Erin Michelle. "Patellofemoral osteoarthritis : characterizing knee alignment and morphology." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/63225.

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The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.<br>Medicine, Faculty of<br>Experimental Medicine, Division of<br>Medicine, Department of<br>Graduate

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