Relevant bibliographies by topics / P53 polymorphism

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'P53 polymorphism'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "P53 polymorphism"

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González-Herrera, Lizbeth, Patricia Rodríguez-Morales, María del Refugio González-Losa, et al. "MTHFR/p53 Polymorphisms as Genetic Factors for Cervical Intraepithelial Neoplasia and Cervical Cancer in HPV-infected Mexican Women." International Journal of Biological Markers 29, no. 2 (2014): 142–49. http://dx.doi.org/10.5301/jbm.5000070.

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We performed a case-control association study to evaluate the association between common polymorphisms in MTHFR (C677T and A1298C) and the Arg72Pro polymorphism in the p53 gene and the risk for cervical intraepithelial neoplasia (CIN) or invasive cervical cancer (ICC) in Mexican HPV-infected women. We included 131 women with diagnosis of CIN grade I-II and 78 with CIN III or ICC; as controls we also included 274 women with normal Pap smear and negative HPV test. Genotyping for MTHFR and p53 polymorphisms was performed by PCR-RFPLs. HPV was tested by Hybrid Capture II. Odds ratios and 95% confi
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SAFFARI, B., L. BERNSTEIN, D. C. HONG, et al. "Association of p53 mutations and a codon 72 single nucleotide polymorphism with lower overall survival and responsiveness to adjuvant radiotherapy in endometrioid endometrial carcinomas." International Journal of Gynecologic Cancer 15, no. 5 (2005): 952–63. http://dx.doi.org/10.1136/ijgc-00009577-200509000-00038.

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p53 genetic alterations are associated with advanced stage and aggressive tumors in a variety of human malignancies. The aim of this study was to examine p53 for genetic alterations and to evaluate the association of these alterations with clinical outcome and response to adjuvant radiotherapy in endometrioid endometrial carcinomas. p53 mutations in exons 2–11 were assessed in 59 endometrioid carcinomas by polymerase chain reaction–single-strand conformational polymorphism and sequence analysis. Twelve mutations (20.3%) and nine polymorphisms were identified. Seven of the nine polymorphisms we
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Engin, Ayse, Bensu Karahalil, Ali Karakaya, and Atilla Engin. "Association Between XRCC1 ARG399GLN and P53 ARG72PRO Polymorphisms and the Risk of Gastric and Colorectal Cancer in Turkish Population." Archives of Industrial Hygiene and Toxicology 62, no. 3 (2011): 207–14. http://dx.doi.org/10.2478/10004-1254-62-2011-2098.

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Association Between XRCC1 ARG399GLN and P53 ARG72PRO Polymorphisms and the Risk of Gastric and Colorectal Cancer in Turkish PopulationGastric cancer is one of the most common cancers of the gastrointestinal system, and its overall five-year survival rate is still 15 % to 20 %, as it can mostly be diagnosed at an advanced stage. On the other hand, although colorectal cancer has a rather good prognosis, mortality is one half that of the incidence.As carcinogenesis is believed to involve reactive radicals that cause DNA adduct formation, impaired repair activity, and weakened tumour suppression,
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Dybikowska, A., A. Dettlaff, K. Konopa, and A. Podhajska. "p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland." Acta Biochimica Polonica 47, no. 4 (2000): 1179–82. http://dx.doi.org/10.18388/abp.2000_3970.

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A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.
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Özbey, Ulku, Hüseyin Yüce, Mustafa Namli, and Tamer Elkiran. "Investigation of Differences in P53 Gene Polymorphisms between Schizophrenia and Lung Cancer Patients in the Turkish Population." Genetics Research International 2011 (March 3, 2011): 1–9. http://dx.doi.org/10.4061/2011/483851.

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Objective. The reduced incidence of cancer observed in schizophrenia patients may be related to differences in genetic background. It has been suggested that genetic predisposition towards schizophrenia is associated with reduced vulnerability to lung cancer, and p53 gene is one of the candidate genes. In our study, we aimed to investigate polymorphisms in the BstUI in exon 4 and MspI in intron 6 restriction sites of the p53 gene in Turkish schizophrenia patients, lung cancer patients, and controls. Material and Methods. Allele and genotype incidence of these polymorphisms with their haplotype
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Shiohara, M., WS el-Deiry, M. Wada, et al. "Absence of WAF1 mutations in a variety of human malignancies." Blood 84, no. 11 (1994): 3781–84. http://dx.doi.org/10.1182/blood.v84.11.3781.bloodjournal84113781.

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A newly cloned gene named wild-type p53-activated fragment 1 (WAF1; also known as p21, Pic-1, Cip-1, or SDI1) is directly regulated by p53 and can itself suppress tumor cell growth in culture. Induction of expression of WAF1 may be an important means by which cells with DNA injury arrest their growth to repair DNA or undergo apoptosis. Based on the hypothesis that mutations of this gene may play a role in carcinogenesis, we have studied 351 DNAs from 14 kinds of malignancies, as well as 36 human transformed cell lines, for alterations of WAF1 gene by single-strand conformation polymorphism ana
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Yi, Ke, LingYun Yang, Zhu Lan, and MingRong Xi. "The Association Between p53 Codon 72 Polymorphism and Endometrial Cancer Risk: A System Review and Meta-analysis." International Journal of Gynecologic Cancer 26, no. 6 (2016): 1121–28. http://dx.doi.org/10.1097/igc.0000000000000725.

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AbstractPolymorphism of p53 codon 72 plays an important role in pathogenesis and development of cancer. Published data on the association between the p53 codon 72 polymorphism and endometrial cancer risk are controversial. A meta-analysis was performed to assess whether the polymorphism of p53 codon 72 is associated with endometrial cancer risk. Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Databases were searched to identify eligible studies. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) for p53 codon 72 polymorphism and endometrial cancer wer
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Zhang, Shengliang, and Wafik S. El-Deiry. "Abstract 2604: Functional analysis of p53 codon 72 polymorphism with cysteine substitution in cancer cells." Cancer Research 83, no. 7_Supplement (2023): 2604. http://dx.doi.org/10.1158/1538-7445.am2023-2604.

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Abstract The p53 codon p72 polymorphism with proline (p53P72)/arginine (p53R72) substitution is associated with cancer incidence. Cysteine(C) substitution at p53 codon 72 polymorphism (p53C72) is rarely studied in cancer patients. A patient who developed AML and who carries p53C72 was described (El-Deiry, 2022 WIN Symposium). The patient’s family has high rates of cancer susceptibility in the women some of whom carry FANCC alterations and other alleles. To examine the functional characteristics of different p53 alterations at codon 72, we generated plasmids expressing p53C72, p53 R72 or p53P72
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Jafari Nedooshan, Jamal, Mohammad Forat Yazdi, Hossein Neamatzadeh, Masoud Zare Shehneh, Saeed Kargar, and Niloofar Seddighi. "Association between TP53 codon 72 G>C Polymorphism and Thyroid Carcinoma Risk: An Up-to-Date Meta-Analysis." Asian Pacific Journal of Cancer Biology 1, no. 4 (2016): 89–95. http://dx.doi.org/10.31557/apjcb.2016.1.4.89-95.

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Objective: Many published data on the association between p53 codon 72 G>C polymorphism and thyroid carcinoma risk showed inconclusive results. The aim this study was to assess the association between p53 codon 72 G>C polymorphism and thyroid cancer risk. Methods: A literature search of PubMed, EMBASE, Google scholar and Web of Science databases for case–control studies examining the association between p53 codon 72 G>C polymorphism and thyroid cancer susceptibility up October 2016 was performed. Odds ratios (OR) with 95 % confidence intervals (95 % CI) were used to assess the strengt
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Helland, Aslaug, and Anne-Lise Børresen-Dale. "p53 polymorphism and cervical cancer." Lancet 354, no. 9189 (1999): 1561–62. http://dx.doi.org/10.1016/s0140-6736(05)76596-x.

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Dissertations / Theses on the topic "P53 polymorphism"

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Glas, Michael. "Mutationsanalyse im p53-Gen bei Patienten mit Multipler Sklerose." Doctoral thesis, [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969662440.

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Makni, Héla. "p53 polymorphism at codon 72 and risk of HPV-induced cervical cancer." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ64401.pdf.

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Koushik, Anita. "The p53 CODON 72 polymorphism and risk of pre-invasive cervical neoplasia /." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84277.

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Introduction. The Arg/Arg genotype vs. Arg/Pro or Pro/ Pro at codon 72 of the p53 gene has been implicated in increasing susceptibility of the cervix to the action of human papillomaviruses (HPV) and thus altering cancer risk. However, research on this topic has been contentious. Meta-analysis and meta-regression analysis, included as part of this project, revealed that studies where departures from Hardy-Weinberg equilibrium were observed tended to report higher odds ratios (OR). In fact, several methodological and study design choices can contribute to such departures. The primary pur
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XUE, BIN. "META ANALYSIS OF THE ASSOCIATION OF p53 CODON 72 VARIATION AND CERVICAL CANCER." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1108234287.

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Ryk, Charlotta. "Influence of genetic polymorphisms on DNA repair, p53 mutations and cancer risk /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-940-8/.

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OKADA, RIEKO, BAKHODIR RAHIMOV, KEUN SOO AHN, et al. "INTERLEUKIN-8 T-251A POLYMORPHISM WAS ASSOCIATED WITH POSITIVE ANTI-p53 ANTIBODIES IN UZBEKISTAN POPULATION." Nagoya University School of Medicine, 2009. http://hdl.handle.net/2237/12351.

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ZIHA, ZARIFI ISABELLE. "Mutations de la p53 dans les cancers du sein : optimisation des conditions de single strand conformation polymorphism." Besançon, 1993. http://www.theses.fr/1993BESA3105.

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Ribeiro, Júnior Circoncisto Laurentino. "ANÁLISE DO POLIMORFISMO DO GENE P53 EM PACIENTES COM CLÍNICA DE ENDOMETRIOSE ASSOCIADO À INFERTILIDADE." Pontifícia Universidade Católica de Goiás, 2009. http://localhost:8080/tede/handle/tede/2419.

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Made available in DSpace on 2016-08-10T10:39:21Z (GMT). No. of bitstreams: 1 CIRCONCISTO LAURENTINO RIBEIRO JUNIOR.pdf: 2083186 bytes, checksum: bfcfede933b252abac1e5de63aa561f2 (MD5) Previous issue date: 2009-03-13<br>Endometriosis it is considered as the presence of ectopic endometrial tissue, with similar histology and function to the endometrium usually located. However, the explanation for the implantation of the endometrial tissue in certain women is still unknown. The determination of the degree of compromising of the endometriosis is based on a system of points proposed by American F
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Sarhanis, P. "Epithelial ovarian cancer : influence of polymorphism at the glutathione - s - transferase GSTM1 and GSTT1 loci on expression of P53." Thesis, Keele University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359971.

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Fagundes, Simone Souza. "RELAÇÃO DO POLIMORFISMO DO GENE TP53 NO CÓDON 72 COM CÂNCER DE MAMA: UMA ATUALIZAÇÃO DE METANÁLISE (2002-2015)." Pontifícia Universidade Católica de Goiás, 2016. http://tede2.pucgoias.edu.br:8080/handle/tede/3524.

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Submitted by admin tede (tede@pucgoias.edu.br) on 2016-10-07T13:26:52Z No. of bitstreams: 1 SIMONE SOUZA FAGUNDES.pdf: 1864838 bytes, checksum: 28db816101558781ede4b2fb42be7695 (MD5)<br>Made available in DSpace on 2016-10-07T13:26:52Z (GMT). No. of bitstreams: 1 SIMONE SOUZA FAGUNDES.pdf: 1864838 bytes, checksum: 28db816101558781ede4b2fb42be7695 (MD5) Previous issue date: 2016-06-27<br>Breast cancer is the most frequent in the world and Brazilian women, except for cases of skin cancer nonmelanoma. It is a complex disease that has no single cause, results from the interaction of multiple ri
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Books on the topic "P53 polymorphism"

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Kanappilly, Antony. Bedeutung des P53 Codon 72 Polymorphismus bei Plattenepithelkarzinomen des Kopf-Hals-Bereiches. 2006.

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Scheunemann, David. Untersuchungen zum Zusammenhang von Infektionen mit humanen Papillomviren und dem Polymorphismus im Codon 72 des p53 Tumorsuppressorproteins in Plattenepithelkarzinomen des Kopf-Hals-Bereiches. 2005.

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Book chapters on the topic "P53 polymorphism"

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Mashiyama, Shoji, Takamasa Kayama, Ryuichi Katakura, et al. "Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products." In Biological Aspects of Brain Tumors. Springer Japan, 1991. http://dx.doi.org/10.1007/978-4-431-68150-2_41.

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Cheng, Theresa M., Vinod Ganju, Steve R. Ritland, Gobinda Sarkar, and Robert B. Jenkins. "[14] Analysis of p53 mutations in human gliomas by RNA single-strand conformational polymorphism." In Methods in Neurosciences. Elsevier, 1995. http://dx.doi.org/10.1016/s1043-9471(06)80092-3.

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Nasif, Zaizafoon Nabeel. "A Comparative Study on The Efficiency of Genomic DNA Extraction Protocols for P53 Gene Polymorphism in Prostate Cancer." In Microbiology and Biotechnology Research: An Overview Vol. 2. BP International, 2025. https://doi.org/10.9734/bpi/mbrao/v2/5158.

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Frebourg, Thierry, Jean-Michel Flaman, Anne Estreicher,, and Richard Iggo. "Functional assay of the p53 tumour suppressor gene." In Mutation Detection. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780199636570.003.0013.

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Abstract Screening methods generally used to detect mutations are commonly based on structural analysis of genes. These methods are often labour-intensive and fail to distinguish inactivating mutations from polymorphisms or functionally silent mutations. The alternative is to use biological assays which test the function of the gene product. This chapter describes a functional assay which detects mutations in human p53 cDNA expressed in the yeast Saccharomyces cerevisiae. Somatic p53 mutations are the most common genetic defect known to occur in human tumours (for a review see ref. 1) and more
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Armando León-Rodríguez, Diego, Julian Becerra, Juan Carlos Caicedo Mera, Luis Fernando Cardenas, Jorge Martínez Cotrina, and Diego Mauricio Aponte Canencio. "OXTR Gene Polymorphisms and Event-Related Potentials in Humans: A Systematic Review." In Oxytocin and Social Function. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.112631.

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Oxytocin receptor (OXTR) gene polymorphisms have been consistently associated with humans’ differences in sensitivity to social cues, social cognition, stress response, and brain activity. However, how social and affective neural processing differs across carriers of distinct OXTR gene polymorphisms remains unclear. This systematic PRISMA review is the first to examine the experimental literature on the relationship between OXTR polymorphisms and ERP components. Eight studies published between 2014 and 2019 were included. The rs53576 was the only OXTR gene polymorphism analyzed in all studies.
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Mariani, BMP, TC Ribeiro, RA Toledo, et al. "Analysis of the D104N Polymorphism of theCOL18A1in Patients with Benign and Malignant Pheochromocytoma." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part3.p13.p3-623.

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Moreira, Ricardo PP, Tania ASS Bachega, Marcio C. Machado, et al. "Modulatory Effect of BclI GR Gene Polymorphism on the Phenotype of Obesity in Cushing Disease." In BASIC/TRANSLATIONAL - Glucocorticoid Disease & Physiology. The Endocrine Society, 2011. http://dx.doi.org/10.1210/endo-meetings.2011.part4.p5.p3-505.

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Diniz, Simone Magalhaes, Sophie Deram, Isabel Guazzelli, Eliana Frazzatto, Thais Arthur, and Sandra Villares. "Cell Death-Inducing DNA Fragmentation Factor Alpha-Like Effector A (CIDEA) V115F (G>T) Polymorphism Associated with Obesity and Metabolic Alterations in Brazilian Obese Children and Adolescents." In CLINICAL - Obesity: Causes & Consequences. The Endocrine Society, 2011. http://dx.doi.org/10.1210/endo-meetings.2011.part3.p35.p3-403.

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Sinha, Anirban, Subhankar Chowdhury, Madhusudan Das, and Kaushik Pandit. "Study of Thyroid Peroxidases (TPO) Gene Polymorphism in Hypothyroidism." In The Endocrine Society's 92nd Annual Meeting, June 19–22, 2010 - San Diego. Endocrine Society, 2010. http://dx.doi.org/10.1210/endo-meetings.2010.part3.p12.p3-568.

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Roef, Greet LLE, Sara Guillemaere, Helene De Naeyer, Sara Vandewalle, Youri EC Taes, and Jean-Marc Kaufman. "Iodothyronine Deiodinase 1 Polymorphisms Are Associated with Body Height." In BASIC/TRANSLATIONAL/CLINICAL - Thyroid Gland Development & Function. The Endocrine Society, 2011. http://dx.doi.org/10.1210/endo-meetings.2011.part4.p8.p3-587.

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Conference papers on the topic "P53 polymorphism"

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Andavolu, Radhika G., Svetlana Rubakovic, Jacob Rubin, et al. "Abstract 2651: Association of p53 codon72 polymorphism, BCCIP & CDKN2A with melanoma risk. A p53-dependent mechanism." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2651.

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Bisultanova, Z. I., P. M. Dzhambetova, M. M. Atsaeva, L. M. Dzhambetova, and Kh Sa Musaeva. "Cytogenetic Effects of Cytostatics and Their Relationship With p53 Gene Polymorphism." In The International Conference “Health and wellbeing in modern society” (ICHW 2020). Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.201001.023.

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Oliveira, Ligia P., Ignacio López, Mónica Marín, and Renata A. Coudry. "Abstract 216: Association of p53 codon 72 polymorphism and colorectal cancer risk." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-216.

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Council, Leona N., Chandrakumar Shanmugam, Venkat R. Katkoori, Meenakshi Sthanam, Alex Hanna, and Upender Manne. "Abstract 1158: Clinical significance of p53 codon 72 polymorphism in hepatocellular carcinomas." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-1158.

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Jennis, Matthew, Monica Hollstein, and Maureen E. Murphy. "Abstract 2964: The codon 47 Pro47Ser polymorphism influences p53 phosphorylation and apoptotic function." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2964.

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Katkoori, Venkat R., Upender Manne, and Harvey Bumpers. "Abstract 781: Functional consequence of the p53 codon 72 polymorphism in colorectal cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-781.

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Lee, Seo-Young, Sun-Ku Chung, Jung-Hyun Park, Soo A. Oh, and Kyoung-Jae Won. "Abstract LB-B10: Transcriptional landscape in the human Knock-in isogenic line for p53 polymorphism codon 72." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-lb-b10.

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Vasileva, Mariia V., Nadejda V. Cherdyntseva, Polina A. Gervas, Valentina A. Belyavskaya, and Vladimir V. Klimov. "P53 codon 72, GSST1, GSTM1 and CCR5del32 genetic polymorphism: Evidence of correlation between asthma and lung cancer." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa541.

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Cai, Jiajing, Yan Cai, Qiang Ma, Dongsheng Wang, Guoyuan Zhang, and Xiaolan Guo. "Abstract 1226: Association of p53 codon72 polymorphism with susceptibility to hepatocellular carcinoma in Chinese population of Northeast Sichuan." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1226.

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Frank, Amanda, Monica Hollstein, and Maureen E. Murphy. "Abstract 2855: The codon 72 polymorphism of p53 influences the transcription of genes involved in immunity and inflammation." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-2855.

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Reports on the topic "P53 polymorphism"

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Paunesku, T., M. A. Gemmell, R. Crkvenjakov, and G. E. Woloschak. Identification of a polymorphic site as a mutational site in exon VI of the mouse p53 gene. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10186830.

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Niguidula, Nancy J. 4-Aminobiphenyl (4-ABP)-DNA Damage in Breast Tissue and Relationship to p53 Mutation and Polymorphisms of Metabolizing Genes. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada403392.

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Niguidula, Nancy J., and Regina M. Santella. 4-Aminobiphenyl (4-ABP)-DNA Damage in Breast Tissue and Relationship to p53 Mutations and Polymorphisms of Metabolizing Genes. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412857.

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