Academic literature on the topic 'Pancreatic neuroendocrine tumour'

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Journal articles on the topic "Pancreatic neuroendocrine tumour"

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Durga, Kharidehal, Nandam Mohan Rao, and Byna Syam Sundara Rao. "Mixed Neuroendocrine - Non-Neuroendocrine Neoplasm (MiNEN) - A Rare Heterogenous Malignancy of the Pancreas." International Journal of Research and Review 10, no. 6 (2023): 306–10. http://dx.doi.org/10.52403/ijrr.20230637.

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Introduction: Pancreatic mixed neuroendocrine non-neuroendocrine neoplasms are extremely rare tumours accounting for 0.5% of all the pancreatic malignancies and 5% of all pancreatic neuroendocrine neoplasms. These tumors are rarely diagnosed preoperatively and they have a poor prognosis. Pancreatic MiNEN is characterized by 2 malignant lesions adenocarcinoma and Neuroendocrine tumour with each constituent involving more than 30% of the tumour. We report a case of 57yr old male with dullaching abdominal pain radiating to back. CA 19-9 was mildly elevated. Other laboratory tests are within norma
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Maslin, D., B. Challis, and H. Simpson. "Metastatic pancreatic neuroendocrine tumour." QJM 109, no. 5 (2016): 355. http://dx.doi.org/10.1093/qjmed/hcw036.

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Mormul, Agata, Emilia Włoszek, Julia Nowoszewska, et al. "Rare Non-Neuroendocrine Pancreatic Tumours." Cancers 15, no. 8 (2023): 2216. http://dx.doi.org/10.3390/cancers15082216.

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The most common tumour of the pancreas is ductal adenocarcinoma (PDAC). It remains one of the most lethal non-neuroendocrine solid tumours despite the use of a multi-approach strategy. Other, less-common neoplasms, which are responsible for 15% of pancreatic lesions, differ in treatment and prognosis. Due to the low incidence rate, there is a lack of information about the rarest pancreatic tumours. In this review, we described six rare pancreatic tumours: intraductal papillary mucinous neoplasm (IPMN), mucinous cystadenoma (MCN), serous cystic neoplasm (SCN), acinar cell carcinoma (ACC), solid
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Ferrel, Benjamin, Jan Franko, and May C. Tee. "Rare case of pancreatic neuroendocrine tumour presenting as paraneoplastic hypercalcaemia." BMJ Case Reports 14, no. 4 (2021): e240786. http://dx.doi.org/10.1136/bcr-2020-240786.

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An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed.
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Weerasuriya, Scott, Kieran Palmer, Stephen Gregory, Benjamin C. Whitelaw, Elisa Gonzalez, and Rajaventhan Srirajaskanthan. "Mesenteric Variceal Haemorrhage and Ectopic Cushing’s Syndrome as Presenting Features of a Pancreatic Neuroendocrine Tumour Recurrence." Case Reports in Gastroenterology 15, no. 3 (2021): 919–26. http://dx.doi.org/10.1159/000518021.

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Pancreatic neuroendocrine tumours can have varied and complex presentations. Whilst hormone hypersecretion often induces characteristic clinical syndromes, non-specific symptoms may arise due to localized tumour effects. Malignant invasion of local vasculature is an increasingly recognized complication of these neoplasms and can be associated with significant morbidity. Herein, we present the case of a 47-year-old male with a recurrence of a pancreatic neuroendocrine tumour who presented with unusual upper gastrointestinal bleeding. The tumour had recurred within the superior mesenteric vein,
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Kann, P. H., E. Balakina, D. Ivan, et al. "Natural course of small, asymptomatic neuroendocrine pancreatic tumours in multiple endocrine neoplasia type 1: an endoscopic ultrasound imaging study." Endocrine-Related Cancer 13, no. 4 (2006): 1195–202. http://dx.doi.org/10.1677/erc.1.01220.

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Endoscopic ultrasound (EUS) enables detection and localization of pancreatic neuroendocrine tumours. Even small tumours down to a diameter of 1–2 mm can be visualized. Since such small tumours usually cannot be detected by computed tomography (ct), magnetic resonance imaging (mri) and somatostatin receptor scintigraphy (srs), and experience with EUS imaging is limited, there is no clear evidence for clinical management in multiple endocrine neoplasia type 1 (MEN1). Knowledge about the natural course of growth and metastatic distribution is mandatory to come to appropriate clinical decisions an
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Laccourreye, Ollivier, Eric Chabardes, Gregory Weinstein, Francoise Carnot, Daniel Brasnu, and Henri Laccourreye. "Synchronous arytenoid and pancreatic neuroendocrine carcinoma." Journal of Laryngology & Otology 105, no. 5 (1991): 373–75. http://dx.doi.org/10.1017/s0022215100116044.

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AbstractNeuroendocrine laryngeal carcinoid tumours are uncommon. The supraglottis is the main location of these tumours. Eighty-one cases have been reported in the world literature. We present the first case of a synchronous laryngeal and pancreatic neuroendocrine tumour.
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Venugopal, Abhirami, Agnes Michalczyk, Mustafa Khasraw, and M. Leigh Ackland. "EMT Molecular Signatures of Pancreatic Neuroendocrine Neoplasms." International Journal of Molecular Sciences 23, no. 21 (2022): 13645. http://dx.doi.org/10.3390/ijms232113645.

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Neuroendocrine neoplasms (NENs) are relatively rare neoplasms occurring predominantly in the gastrointestinal tract and pancreas. Their heterogeneity poses challenges for diagnosis and treatment. There is a paucity of markers for characterisation of NEN tumours. For routine diagnosis, immunohistochemistry of the NEN-specific markers CgA and synaptophysin and the proliferation marker Ki-67 are used. These parameters, however, are qualitative and lack the capacity to fully define the tumour phenotype. Molecules of epithelial–mesenchymal transition (EMT) are potential candidates for improved tumo
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Bertani, Helga, Alessandro Messerotti, Fabrizio Di Benedetto, et al. "Unusual Paraneoplastic Syndrome Accompanies Neuroendocrine Tumours of the Pancreas." Case Reports in Medicine 2011 (2011): 1–4. http://dx.doi.org/10.1155/2011/309149.

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Neuroendocrine tumours comprise a small percentage of pancreatic neoplasia (10%) (1). Diagnosis of neuroendocrine tumours is difficult, especially if the tumours are small and nonfunctional. CT scans, MRI, and nuclear scans are sufficiently sensitive assessment tools for tumours with diameters of at least 2 cm; otherwise, the sensitivity and specificity of these techniques is less than 50% (2). Myasthenia gravis (MG) is a heterogeneous neuromuscular junction disorder that is primarily caused when antibodies form against the acetylcholine receptors (Ab-AchR). MG can develop in conjunction with
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Lines, K. E., R. P. Vas Nunes, M. Frost, C. J. Yates, M. Stevenson, and R. V. Thakker. "A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control." Endocrine Connections 6, no. 4 (2017): 232–42. http://dx.doi.org/10.1530/ec-17-0040.

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Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by occurrence of parathyroid tumours and neuroendocrine tumours (NETs) of the pancreatic islets and anterior pituitary. The MEN1 gene, encoding menin, is a tumour suppressor, but its precise role in initiating in vivo tumourigenesis remains to be elucidated. The availability of a temporally controlled conditional MEN1 mouse model would greatly facilitate the study of such early tumourigenic events, and overcome the limitations of other MEN1 knockout models, in which menin is lost from conception or tumou
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Dissertations / Theses on the topic "Pancreatic neuroendocrine tumour"

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Gill, Preetjote. "Studies In Patients With Surgically Resected Pancreatic Neuroendocrine Tumours - MicroRNA Expression And Clinical Correlation." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18181.

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INTRODUCTION Pancreatic Neuroendocrine Tumours (PNETS) have increased in incidence over the past three decades. Treatment options currently include surgery, locoregional and systemic therapies, however the prognosis remains poor and biomarkers that accurately predict the clinical behavior of these tumours are lacking. Dysregulation of microRNAs (miRNAs) has recently been shown to play a role in the development of many cancers through post-transcriptional gene regulation, however, few studies have investigated the role of miRNAs as diagnostic or prognostic markers in PNETs. METHODS Patients un
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De, Cassan Chiara. "Elastography mean strain histogram value for the differential diagnosis of malignant pancreatic masses: a monocentric study." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424524.

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Introduction Endoscopic ultrasound (EUS) elastography is a recent ultrasound method used for the real-time visualization and evaluation of tissue elasticity. Qualitative and quantitative methods have been used, in particular in evaluation of pancreatic diseases and malignant lymph nodes, with interesting results regarding the accuracy and the differential diagnosis between malignant and benign masses. No consensus has been reached with regard to the superiority of different quantitative methods, but strain ratio and strain histogram (SH) remain the most used. SH corresponds to a graphical re
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Hanson, Matthew Richard. "Expression studies on PPARγ in pancreatic neuroendocrine tumours". Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/710.

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Pancreatic NETs occur with an annual incidence of around 5 per 1,000,000 population per year, with survival rates of between 30 – 97% at 5 years depending on the tumour subtype. The PPARs (peroxisomal proliferator-activated receptors) are members of the nuclear receptor superfamily that includes receptors for thyroid, steroid and retinoid hormones. PPARγ protein is also thought to be expressed in human pancreatic islet cells and has been shown to be a negative regulator of islet β cell mass both in vivo and in vitro. Its emerging function in controlling cell proliferation, differentiation and
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Bösch, Florian [Verfasser], and Markus [Akademischer Betreuer] Guba. "Single center experience in pancreatic neuroendocrine tumors / Florian Bösch. Betreuer: Markus Guba." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1081899859/34.

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Yamauchi, Yuki. "Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264634.

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京都大学<br>新制・論文博士<br>博士(医学)<br>乙第13418号<br>論医博第2226号<br>新制||医||1052(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 羽賀 博典, 教授 長船 健二, 教授 伊藤 貴浩<br>学位規則第4条第2項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM
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Körner, Jan Lennart [Verfasser], and Roland [Akademischer Betreuer] Kontermann. "Target identification and probe development for pancreatic neuroendocrine tumors / Jan Lennart Körner. Betreuer: Roland Kontermann." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2015. http://d-nb.info/1069290211/34.

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ANDREASI, VALENTINA. "ROLE OF CHROMOGRANIN A-DERIVED FRAGMENTS AND OTHER BIOMARKERS IN PANCREATIC NEOPLASMS: FOCUS ON NEUROENDOCRINE TUMORS." Doctoral thesis, Università Vita-Salute San Raffaele, 2021. http://hdl.handle.net/20.500.11768/121777.

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Introduction: The lack of valid biomarkers represents a major unmet clinical need in pancreatic neuroendocrine neoplasms (PanNENs). Chromogranin A (CgA) is the most commonly measured PanNEN biomarker, despite relevant limitations related to variable sensitivity, poor specificity and lack of assay standardization. Therefore, novel biomarkers are needed to improve diagnosis, detect disease recurrence and assess treatment response. In this project, the role of CgA-derived fragments as PanNEN biomarkers was investigated, focusing on the N-terminal peptide vasostatin-1 (VS-1). A multianalyte biomar
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Örlefors, Håkan. "Positron Emission Tomography in the Management of Neuroendocrine Tumors." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3356.

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<p>Neuroendocrine tumors (NET´s) are often characterized by overproduction of peptide hormones. In spite of pronounced clinical symptoms, the tumor lesions can be small and difficult to detect. The general aim of this thesis was to investigate, in vitro and in vivo, some of the potential monoamine pathways present in NET´s, using radiolabeled tracers for positron emission tomography (PET), with the intention to explore the value of PET-imaging in the management of NET´s.</p><p>We used the 11C-labeled serotonin precursor 5-hydroxy tryptophan (HTP) as the tracer for imaging of NET´s. More than 9
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Capodanno, Ylenia. "Identifying therapeutic implications of cancer stem cells in human and canine insulinoma." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31175.

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Pancreatic neuroendocrine tumours (PNETs) are the most common neuroendocrine tumours diagnosed in humans and dogs. Due to the highly heterogeneous nature of these tumours, definitive data are still lacking over the molecular mechanisms involved in their cancerous behaviour. This study focused on insulinoma (INS), as it is the most commonly diagnosed PNET in human and veterinary oncology. INS is an insulin-producing tumour that causes a hypoglycaemic syndrome related to the excessive insulin production. In humans, it is often a small benign neoplasm readily curable by surgical resection whereas
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Ekeblad, Sara. "Pancreatic Endocrine Tumors and GIST - Clinical Markers, Epidemiology and Treatment." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7937.

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Books on the topic "Pancreatic neuroendocrine tumour"

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Pisegna, Joseph R., ed. Management of Pancreatic Neuroendocrine Tumors. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1798-3.

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Khayat, Eric. Tumeurs neuroendocrines digestives et médecine nucléaire. Editions médicales internationales, 2001.

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Bertram, Wiedenmann, ed. Molecular and cell biological aspects of gastroenteropancreatic neuroendocrine tumor disease. New York Academy of Sciences, 1994.

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Carton, James. Pancreatic pathology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759584.003.0009.

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This chapter discusses pancreatic pathology and covers pancreatic malformations, acute pancreatitis, chronic pancreatitis, pancreatic ductal carcinoma, pancreatic neuroendocrine tumours, pancreatic cystic tumours, and acinar cell carcinoma.
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Pisegna, Joseph R. Management of Pancreatic Neuroendocrine Tumors. Springer New York, 2016.

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Pisegna, Joseph R. Management of Pancreatic Neuroendocrine Tumors. Springer, 2014.

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Pisegna, Joseph R. Management of Pancreatic Neuroendocrine Tumors. Springer, 2014.

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Pancreatic Cancer Cystic and Endocrine Neoplasm. John Wiley and Sons Ltd, 2014.

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Howe, James R. Management of GI and Pancreatic Neuroendocrine Tumors,an Issue of Surgical Oncology Clinics of North America. Elsevier, 2020.

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Book chapters on the topic "Pancreatic neuroendocrine tumour"

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Koumarianou, Anna, and Nicola Fazio. "Nonfunctioning Pancreatic Neuroendocrine Tumors." In Neuroendocrine Tumours. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45215-8_18.

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Fazio, Nicola, and Anna Koumarianou. "Non-Functioning Pancreatic Neuroendocrine Tumors." In Neuroendocrine Tumours. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-56968-5_18.

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Komminoth, Paul. "Somatostatin-Producing Tumor." In Pancreatic Neuroendocrine Neoplasms. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17235-4_10.

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Uccella, Silvia, Roberta Maragliano, and Francesca Magnoli. "ACTH-Producing Tumor." In Pancreatic Neuroendocrine Neoplasms. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17235-4_13.

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La Rosa, Stefano, Nora Sahnane, and Laura Cimetti. "Serotonin-Producing Tumor." In Pancreatic Neuroendocrine Neoplasms. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17235-4_14.

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Chew, C., and G. K. Bonney. "Pancreatic Neuroendocrine Tumours." In Evidence-Based Endocrine Surgery. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-1124-5_36.

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Tamburrino, Domenico, Stefano Partelli, and Massimo Falconi. "Pancreatic Neuroendocrine Tumours." In Surgical Diseases of the Pancreas and Biliary Tree. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8755-4_13.

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Johnson, Paul R. V. "Pancreatic Neuroendocrine Tumours." In Endocrine Surgery in Children. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54256-9_13.

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Bennett, Sean Alexander, Calvin How Lim Law, Angela Assal, Sten Myrehaug, and Julie Hallet. "Functional Pancreatic Neuroendocrine Tumors." In Neuroendocrine Tumors. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-62241-1_9.

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Park, Young Suk. "Less Common Types of Pancreatic Neuroendocrine Tumors." In Neuroendocrine Tumours. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45215-8_17.

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Conference papers on the topic "Pancreatic neuroendocrine tumour"

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Souto, Andreza Karine de Barros Almeida, Poliana Bergamaschine Giovani Blasi, Brenda Fabiola Delgado Taboada, Fernanda Teresa Lima, Bernardo Garicochea, and Cristiano Augusto Andrade de Resende. "NEUROENDOCRINE CARCINOMA OF THE BREAST AND ILEUM IN A PATIENT WITH BRCA2 PATHOGENIC VARIANT – ONCOLOGIC AND GENETIC CONSIDERATIONS DERIVED FROM A CASE REPORT." In Brazilian Breast Cancer Symposium 2022. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s2076.

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Background: Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms. Most frequently, they occur in the digestive system, and breast neuroendocrine tumors constitute less than 1% of all of them. Germline mutations can increase the risk of developing tumors and predispose to hereditary cancer syndromes. Some NENs are well-established components of common hereditary syndromes. Recently, whole genomic sequencing revealed that 17% of apparently sporadic pancreatic NENs carried germline mutations, including DNA repair genes, such as BRCAs. It is well known that this gene plays a role
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Arnez, Marco Antonio Cuellar, Leonardo Brasileiro Marques, Ana Livia Felipe Dias, Gabrielle Gadelha Costa, Gustavo Lopes Teixeira, and Alexandre de Medeiros Silva. "PANCREATIC NEUROENDOCRINE TUMOR MIMICKING IMMUNOGLOBULIN G4-RELATED DISEASE." In XLI Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2024. https://doi.org/10.47660/cbr.2024.2643.

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Simon, T., S. Mamlouk, S. Khouja, et al. "PO-329 Genomic aberration in pancreatic neuroendocrine tumours (PNET)." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.359.

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Zhu, Zhuotun, Yongyi Lu, Wei Shen, Elliot K. Fishman, and Alan L. Yuille. "Segmentation for Classification of Screening Pancreatic Neuroendocrine Tumors." In 2021 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW). IEEE, 2021. http://dx.doi.org/10.1109/iccvw54120.2021.00379.

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Witt, D., B. L. Levarge, and F. B. Askin. "Unilateral Pulmonary Tumor Emboli And Lymphangitic Carcinomatosis From Pancreatic Neuroendocrine Tumor." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5490.

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Mpilla, Gabriel B., Amro Aboukameel, Md Hafiz Uddin, et al. "Abstract 1122: Novel targets for therapy resistant pancreatic neuroendocrine tumors." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1122.

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Cazacu, IM, IF Cherciu Harbiyeli, A. Constantin, et al. "Hypervascular Pancreatic Lesions on Contrast-Enhanced EUS: Beyond Neuroendocrine Tumors." In ESGE Days 2021. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1724433.

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Huang, Jingzhi, Xiaohua Xie, Manxia Lin, Ming Xu, Guangliang Huang, and Xiaoyan Xie. "IDDF2020-ABS-0041 Pancreatic neuroendocrine tumors: correlation between the sonographic features and the pathological tumor grade." In Abstracts of the International Digestive Disease Forum (IDDF), 22–23 November 2020, Hong Kong. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2020. http://dx.doi.org/10.1136/gutjnl-2020-iddf.49.

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Contractor, Tanupriya, Chang Chan, Shinta Kobayashi, et al. "Abstract 3185: Complement C5 promotes male bias of pancreatic neuroendocrine tumor metastasis." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3185.

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Maeng, Kyungah, Hye Seung Lee, Min Chen, and Maria Zajac-Kaye. "Abstract 3922: Deregulated thymidylate synthase promotes tumorigenecity in pancreatic neuroendocrine tumors." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3922.

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