Relevant bibliographies by topics / Parenchymal tumor cells

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Academic literature on the topic 'Parenchymal tumor cells'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Parenchymal tumor cells"

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Wolf, Gregory T., Jerry L. Hudson, Karen A. Peterson, Harriet L. Miller, and Kenneth D. Mcclatchey. "Lymphocyte Subpopulations Infiltrating Squamous Carcinomas of the Head and Neck: Correlations with Extent of Tumor and Prognosis." Otolaryngology–Head and Neck Surgery 95, no. 2 (1986): 142–52. http://dx.doi.org/10.1177/019459988609500203.

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Because little is known about the mechanisms involved in local tumor-host immune reactions in squamous carcinoma of the head and neck, a study was undertaken to better characterize the types of immune cells present at the local tumor site and determine their relationship to tumor extent, systemic cellular immune parameters, and clinical outcome. In 40 untreated patients, lymphocyte subsets (LS) at the tumor-host interface were quantitated immunohistologically from serial sections of frozen tumor specimens and correlated with concurrently measured peripheral LS levels and in vitro lymphocyte re
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Szabo, Peter M., George Lee, Scott Ely, et al. "CD8+ T cells in tumor parenchyma and stroma by image analysis (IA) and gene expression profiling (GEP): Potential biomarkers for immuno-oncology (I-O) therapy." Journal of Clinical Oncology 37, no. 15_suppl (2019): 2594. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2594.

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2594 Background: Distribution patterns of CD8+ T cells within the tumor microenvironment (TME) can be assessed by IA, which may reflect underlying tumor biology and serve as a potential biomarker to assess the utility of I-O therapy. These patterns are variable and may be classified as immune desert (minimal infiltrate), excluded (T cells confined to tumor stroma or to the invasive margin), or inflamed (T cells diffusely infiltrating tumor parenchyma and stroma). We hypothesized that association of a GEP signature with abundance of parenchymal and stromal T-cell infiltrates may identify biomar
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Nwajei, Felix, Meenakshi Shanmugasundaram, Dana Paine, et al. "Brain tumor-induced neuronal stress orchestrates adaptive immune surveillance through fractalkine." Journal of Immunology 200, no. 1_Supplement (2018): 178.13. http://dx.doi.org/10.4049/jimmunol.200.supp.178.13.

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Abstract Tissue damage contributes to initiation and modulation of an immune response. Tumor progression generally causes distress to the surrounding tissue. However, how tumor-induced parenchymal damage regulates anti-tumor immune response remains to be understood. We found that tumors that invaded brain parenchyma compressed the surrounding neurons causing increased expression of the neuronal chemokine CX3CL1/fractalkine in the peritumoral margin. Intravital two-photon microscopy revealed perivascular recruitment of monocyte-derived CD11c+ dendritic cells and T cells that interacted and kill
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BD, Impana, Seethalakshmi S, and Raghavendran R. "A rare and challenging case of pineal gland tumor – A case report." IP Journal of Diagnostic Pathology and Oncology 8, no. 3 (2023): 181–84. http://dx.doi.org/10.18231/j.jdpo.2023.043.

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Pineal gland tumors are of rare occurrence and may arise from pineal parenchymal cells, the neighboring glia or residual stem cells. Due to its rarity pineal gland tumors are often misdiagnosed. The World Health Organsation (WHO) classifies and grades pineal parenchymal tumors from grade I to grade IV. We present a case report of a rare pineal parenchymal tumor (PPT) in an adult female which was diagnosed mainly on histopathology and aided by immunohistochemistry. The case report includes review of histopathological features and grading of pineal region tumors of intermediate malignancy which
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Takabatake, Kiyofumi, Hotaka Kawai, Haruka Omori, et al. "Impact of the Stroma on the Biological Characteristics of the Parenchyma in Oral Squamous Cell Carcinoma." International Journal of Molecular Sciences 21, no. 20 (2020): 7714. http://dx.doi.org/10.3390/ijms21207714.

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Solid tumors consist of the tumor parenchyma and stroma. The standard concept of oncology is that the tumor parenchyma regulates the tumor stroma and promotes tumor progression, and that the tumor parenchyma represents the tumor itself and defines the biological characteristics of the tumor tissue. Thus, the tumor stroma plays a pivotal role in assisting tumor parenchymal growth and invasiveness and is regarded as a supporter of the tumor parenchyma. The tumor parenchyma and stroma interact with each other. However, the influence of the stroma on the parenchyma is not clear. Therefore, in this
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Kälin, Roland, Linzhi Cai, Yuping Li, et al. "OTME-1. TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression." Neuro-Oncology Advances 3, Supplement_2 (2021): ii13. http://dx.doi.org/10.1093/noajnl/vdab070.052.

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Abstract Aggressive brain tumors like glioblastoma depend on support by their local environment and subsets of tumor parenchymal cells may promote specific phases of disease progression. We investigated the glioblastoma microenvironment with transgenic lineage-tracing models, intravital imaging, single-cell transcriptomics, immunofluorescence analysis as well as histopathology and characterized a previously unacknowledged population of tumor-associated cells with a myeloid-like expression profile (TAMEP) that transiently appeared during glioblastoma growth. TAMEP of mice and humans were identi
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Kälin, Roland, Linzhi Cai, Dongxu Zhao, et al. "Local progenitor cells shape the neoplastic vasculature and promote brain tumor growth." Journal of Clinical Oncology 39, no. 15_suppl (2021): e14044-e14044. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e14044.

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e14044 Background: Aggressive brain tumors like glioblastoma depend on support by their local environment. While the role of tumor-associated myeloid cells on glioblastoma progression is well-documented, we have only partial knowledge of the pathological impact of glioblastoma -parenchymal progenitor cells. Methods: We investigated the glioblastoma microenvironment with transgenic lineage-tracing models ( nestin-creER2, R26-tdTomato and sox2-creER2,R26-tdTomato), intravital imaging, single-cell transcriptomics, immunofluorescence and flow-cytometry as well as histopathology and characterized a
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Sulistyo, Eko, and Ildsa Maulidya Mar’athus N. "DIFFERENCE IMPLEMENTATION OF T1WI SE AND T1WI FSPGR BRAVO SEQUENTS IN MRI BRAIN TUMOR." Journal of Applied Health Management and Technology 1, no. 1 (2019): 23–27. http://dx.doi.org/10.31983/jahmt.v1i1.5307.

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Tumor is basically an uncontrolled growth of cancerous cells in any part of the body, whereas a brain tumor is an uncontrolled growth of cancerous cells in the brain. Useing of MRI in diagnose tumors can be done with various sequences. Contrast medium is needed to evince tumor enhancement, as well as sequences that support to produce tumor in post contrast, one of which uses a conventional sequence T1WI SE. This sequences often lose information in providing images in cases of brain tumors and generally more time consuming. FSPGR BRAVO is a 3D volumetric acquisition that captures thin section i
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Chekol, Seble S., and Chen-Chin Sun. "Malignant Mesothelioma of the Tunica Vaginalis Testis: Diagnostic Studies and Differential Diagnosis." Archives of Pathology & Laboratory Medicine 136, no. 1 (2012): 113–17. http://dx.doi.org/10.5858/arpa.2010-0550-rs.

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Malignant mesothelioma of the tunica vaginalis testis is an extremely rare tumor representing 0.3% to 5% of all malignant mesotheliomas. Gross examination of testicular mesotheliomas typically reveals tumor nodules studding the thickened tunica vaginalis and, in some cases, infiltrating the testicular parenchyma, leading to diagnostic challenges. Microscopically, the tumor is characterized by epithelioid cells arising from the tunica vaginalis with papillary, tubulopapillary, or solid architectural patterns. The papillae are usually lined by a single layer of cells with relatively bland cytolo
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Jiang, Wulin, Alain Valdivia, Alison Mercer-Smith, Carey Anders, and Shawn Hingtgen. "EXTH-02. TUMOR-HOMING INDUCED NEURAL STEM CELL THERAPY INHIBITS THE PROGRESSION OF BREAST CANCER BRAIN METASTASIS AND LEPTOMENINGEAL CARCINOMATOSIS." Neuro-Oncology 22, Supplement_2 (2020): ii86—ii87. http://dx.doi.org/10.1093/neuonc/noaa215.356.

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Abstract INTRODUCTION Breast cancer brain metastasis, including leptomeningeal carcinomatosis (LC), remains one of the most lethal CNS diseases. New therapies are urgently needed to treat this highly aggressive disease. Here we used models of both breast cancer brain parenchymal metastasis and leptomeningeal metastasis to investigate the efficacy of engineered tumor-homing neural stem cells (NSCs) therapy. METHODS Personalized NSCs were created using Sox2 overexpression to transdifferentiate human fibroblasts into induced NSCs (iNSCs), followed by genetic engineering to enable iNSCs to secrete
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Books on the topic "Parenchymal tumor cells"

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Felbaum, Daniel R., Jonathan H. Sherman, and Walter C. Jean. Pineal Tumors. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190696696.003.0003.

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Pineal region tumors can include a variety of histologies including pineal parenchymal tumor, germ cell tumor, glial tumor, metastasis and meningioma. The workup for pineal region tumors includes standard magnetic resonance imaging for anatomic imaging, as well as cerebrospinal fluid markers to assess for certain germ cell tumors. Cerebrospinal fluid diversion may be necessary if patients present with hydrocephalus. If surgical resection is indicated based on the suspected diagnosis, magnetic resonance venogram is an important study that influences the surgical trajectory. This chapter reviews
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Theeler, Brett J., and Mark R. Gilbert. Primary Central Nervous System Tumors. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0129.

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Ependymomas are rare primary central nervous system (CNS) tumors that are thought to arise from ependymal cells lining the ventricular system located throughout the CNS. Ependymomas occur in all age groups but are more common in the pediatric population. Ependymomas typically present as mass lesions within the ventricular system, brain or spinal cord parenchyma. As with most central nervous system tumors, pathologic evaluation is required for definitive diagnosis. Ependymomas are typically treated with a combination of surgery and radiotherapy although this varies depending on tumor location,
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Book chapters on the topic "Parenchymal tumor cells"

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Lawal, Ismaheel O., Alfred Morgenstern, Otto Knoesen, Mariza Vorster, Frank Bruchertseifer, and Mike M. Sathekge. "Therapy of Castration-Resistant Prostate Cancer: Where Is the Place of 225Ac-PSMA?" In Beyond Becquerel and Biology to Precision Radiomolecular Oncology: Festschrift in Honor of Richard P. Baum. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-33533-4_26.

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AbstractSince the first report in 2004 confirming the survival advantage conferred by docetaxel in the treatment of men with metastatic castration-resistant prostate cancer (mCRPC), many more agents have also been found to prolong life and are now in routine use in clinical practice. Despite the multitude of these effective agents, mCRPC remains a fatal disease with a poor prognosis. Efforts to develop more effective therapies are, therefore, ongoing. Targeting prostate-specific membrane antigen (PSMA) overexpressed on prostate cancer cells has become an attractive option for mCRPC treatment.
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Tomita, Tadanori. "Pineal Tumor." In Pediatric Neurosurgery. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190617073.003.0019.

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A diagnosis of pineal region tumor requires a thorough history, physical exam, neuroimaging, and tumor markers. A computed tomography (CT) scan may demonstrate pineal calcification engulfed by the tumor or displaced peripherally. Magnetic resonance imaging (MRI) should be carefully evaluated for contrast enhancement patterns and multifocal disease. Hydrocephalus is common and may be the primary cause of the symptoms at presentation. Cerebrospinal tumor markers need to be performed if the physician suspects germ cell tumor. In children, germ cell tumors are a more common tumor pathology than pi
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Sorcini, Andrea, and John A. Libertino. "Inferior vena caval tumors." In Biology and management. Oxford University PressOxford, 2003. http://dx.doi.org/10.1093/oso/9780198508229.003.0028.

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Abstract Renal cell carcinoma (RCC) has the propensity to infiltrate the surrounding parenchyma, to penetrate the capsule and extend into the perirenal adipose tissue and adjacent structures, and, in particular, to infiltrate the venous system and propagate into the inferior vena cava (IVC). Electron microscopy reveals renal tumor cells around thin-walled vessels and small fenestrations with the neoplastic process prolapsing into the lumen. These characteristics are consistent with RCC, but they have been described in con- junction with adrenocortical carcinomas and Wilms’ tumors.
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Pantuck, Allan J., Mitchell K. Rauch, Amnon Zisman,, and Arie Belldegrum. "Diagnosis and management of the incidental renal mass." In Biology and management. Oxford University PressOxford, 2003. http://dx.doi.org/10.1093/oso/9780198508229.003.0003.

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Abstract Malignant tumors of the kidney comprise 2 per cent of cancer incidence and mortality in the US (Landis et al. 1998) with 31 200 new cases estimated to occur in the year 2000 causing approximately 11 900 deaths (Greenlee et al. 2000). In general, no distinction has been made in the past between parenchymal and pyelocalyceal tumors from an epidemiological standpoint, and little information is available to separate the two incidence rates. By conservative estimate, however, more than 80 per cent of these tumors will arise in the renal parenchyma (Devasa et al. 1990) and the vast majority
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Jouvet, Anne, François Fauchon, Eric Bouffet, Ghislaine Saint-Pierre, Jacques Champier, and Michelle Montange. "Tumors of pineal parenchymal and glial cells." In Russell & Rubinstein's Pathology of Tumors of the Nervous System 7Ed. CRC Press, 2006. http://dx.doi.org/10.1201/b13439-34.

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Abla, Oussama, and Jennifer Picarsic. "Histiocytic tumors of the central nervous system." In Oxford Textbook of Neuro-Oncology, 2nd ed., edited by Tracy Batchelor and Michael Weller. Oxford University PressOxford, 2025. https://doi.org/10.1093/med/9780198869702.003.0021.

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Abstract Histiocytoses are heterogeneous neoplasms of the haematopoietic system characterized by the accumulation of histiocytes with variable inflammatory infiltrates. The identification of the crucial role of the mitogen-activated protein kinase pathway has opened the door to new targeted therapies. This chapter reviews the central nervous system (CNS) manifestations and treatment of five histiocytic disorders: Langerhans cell histiocytosis (LCH), juvenile xanthogranuloma (JXG), anaplastic lymphoma kinase (ALK)-positive histiocytosis, Erdheim–Chester disease (ECD), Rosai–Dorfman–Destombes di
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Waqar, Mueez, Samantha Mills, Conor L. Mallucci, and Michael D. Jenkinson. "Pineal tumours." In Oxford Textbook of Neurological Surgery, edited by Ramez W. Kirollos, Adel Helmy, Simon Thomson, and Peter J. A. Hutchinson. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198746706.003.0036.

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Tumours of the pineal are very rare, tend to be more common in children and while there are a wide variety of pathologies the majority are germ cell tumours and pineal parenchymal tumours. These tumours usually present with hydrocephalus and endoscopic third ventriculostomy is the operation of choice. It is important to test for tumour markers in the blood and cerebrospinal fluid, since the diagnosis of a secreting germ cell tumour precludes the need for surgery. Surgical biopsy can be performed by endoscopy or with frame-based stereotaxy. For germ cell tumours chemotherapy and radiotherapy ar
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Kortmann, R. D. "Pineal parenchymal tumors, embryonal tumors, and germ cell tumors." In Handbook of Clinical Neurology. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-444-53502-3.00012-4.

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Costa, Rachel Calazans de Oliveira, Paula Melo Vale, André Tunes de Paula, and Taynná Ferreira Arantes da Costa. "AVALIAÇÃO DA FUNÇÃO RENAL PRÉ-OPERATÓRIA EM NEFRECTOMIA." In I Simpósio Acadêmico de Urologia e Robótica. Even3 Publicações, 2023. http://dx.doi.org/10.29327/5213855.1-5.

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INTRODUÇÃO: A cintilografia renal (CR) é um exame de imagem que se baseia na aplicação endovenosa de radiofármaco para avaliação da anatomia, função e patologias renais. As indicações da CR decresceram com a melhora da propedêutica para a análise da anatomia renal. Porém a CR ainda é essencial para avaliação da função renal, sendo que a função glomerular e a tubular são as duas principais avaliadas. Certas condições clínicas são candidatas à avaliação por meio da CR, tais como: hipertensão renovascular, uropatia obstrutiva, anomalias renais, transplante renal, trauma, massas renais, além de se
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Conference papers on the topic "Parenchymal tumor cells"

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Suhas, K. R. "Audit on the role and efficacy of PET/CT in recurrent ovarian cancer settings in a tertiary care centre in India." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685301.

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Ovarian cancers tend to recur in 15-70% cases. CA-125 - is a tumor marker used for monitoring therapeutic response, and in surveillance, for recurrent disease. However, it has a limited role as a persistent high level can signify either recurrence or persistence of residual tumor. Metastases from ovarian cancer primarily involve the peritoneum rather than parenchymal sites; thus, the presence of small-volume recurrence or metastatic deposits on the visceral surfaces poses a challenge for interpretation of CT and MR images. PET/CT utilizes its property of higher accumulation in malignant cells
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Arora, Rahul D. "Definition, etiopathogenesis, management and role of flouroquinolone prophylaxis in prevention of spontaneous bacterial peritonitis complicating malignant ascites." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685345.

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Background: Malignancy related ascites encompasses multiple etiologies which include peritoneal carcinomatosis, hepatic synthetic dysfunction due to parenchymal involvement by the tumour, transcoeloemic metastasis and chylous ascites due to lymphatic obstruction. Primary Cancer type, liver metastasis and serum albumin have been listed as independent prognostic markers in malignant ascites. Spontaneous Bacterial Peritonitis is usually seen as a complication of decompensated chronic liver disease due to translocation of bacteria or haematogenous dissemination from a distant focus of infection. T
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Negrão, Erika Marina Solla, Livia Conz, Silvia Maria Prioli de Souza Sabino, Anapaula Hidemi Uema Watanabe, Jane Camargo da Silva Santos Picone, and Edmundo Carvalho Mauad. "GRANULAR CELL TUMOR SIMULATING BREAST CANCER ON SCREENING MAMMOGRAM: CASE REPORT." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2115.

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Introduction: Granular cell tumor involving the breast parenchyma is very rare, representing between 5 and 15% of the presentations of this tumor. Due to the appearance of the image, it is confused with breast carcinoma; therefore, it can be a diagnostic challenge for medical mastologists, radiologists, and pathologists. Presentation of the case: We report the case of a 45-year-old woman who presented a lesion identified by ultrasound image with characteristics classified as highly suspected of malignancy (BIRADS 4c). The screening mammography detected a dense image of obscured margins, and th
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Ramos, Lilian de Sá Paz, Juliana Almeida Frank, Suzana Imbassahy de Sá Bittencourt Câmara e. Silva, and Diogo Silva Almeida. "POROCARCINOMA IN MALE BREAST." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1078.

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Introduction: Porocarcinoma (PC) is a malignant neoplasm of the eccrine sweat glands, corresponding to 0.005% to 0.001% of skin tumors. There are reports of only two cases with primary localization on the breast from a total of 206 cases of pororcarcinoma according to a systematic review conducted by Nazeemi et al. (2018), from 1963 to 2017. The most common anatomical locations are the lower limbs, the head and the neck. This pathology affects elderly individuals and has a similar incidence among genders. This malignant neoplasm usually presents as a single nodule or a plaque with a verrucous
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Larkin, Riley, Diana Lopez, Yvette Robbins, Gary Gallia, Clint Allen, and Nyall London. "Multispectral Immunofluorescence Analysis of the Esthesioneuroblastoma Tumor Immune Microenvironment Reveals T-Cell Stroma Localization and Tumor Parenchyma Exclusion." In 32nd Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/s-0043-1762050.

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Wang, Guanwu, Dong Liu, Tarick M. Al-Masri, et al. "Body composition in cholangiocarcinoma affects immune cell populations in the tumor and normal liver parenchyma." In 40. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag, 2024. http://dx.doi.org/10.1055/s-0043-1777551.

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Caires, Elisana Maria Santos, Régis Resende Paulinelli, Miliana Tostes Lucatto, Eneida Ribeiro Marinho, and Henrique Moura de Paula. "BREAST IMPLANT–ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA (BIA-ALCL): A CASE REPORT WITH ATYPICAL SYMPTOMS." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2096.

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The BIA-ALCL is a rare type of T-cell lymphoma CD30+ e AKL−, occurring more common in women with Allergantextured implants. It presents most frequently as a late-onset accumulation of seroma fluid between the implant and less frequently as a palpable tumor mass, with malignant cells infiltrating through the capsule and surrounding tissue with potential lymph node and systemic involvement. This article describes a case report of a 65-year-old female patient with BIA-ALCL complaining of erythema in her right breast for almost 7 months. She agreed no family history of cancer and no fever. The pat
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Rocks, Natacha, Catherine Gerard, Christelle Sepult, et al. "Use of a semi-automatic human-supervised procedure for quantitative histology: Modulation of tumour cell dissemination in lung parenchyma." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2837.

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Rocks, Natacha, Catherine Gerard, Christelle Sépult, et al. "LSC Abstract – Use of a semi-automatic human-supervised procedure for quantitative histology: Modulation of tumour cell dissemination in lung parenchyma." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pp119.

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Carvalho, Gabriella Ferreira, Larissa Santana Bitencourt, Isis Coimbra de Almeida Sampaio, Mauro Fróes Assunção, and Mariana Rafaella Dantas Cordeiro. "BREAST ANGIOSSARCOMA IN A MALE PATIENT: A CASE REPORT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1010.

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Primary sarcomas of the breast originate from connective tissue and are responsible for less than 1% of all breast malignancies with an incidence of 5 cases per million in the United States. Primary breast angiosarcoma originates in the parenchyma and can secondarily compromise the skin and pectoral muscles in advanced cases. Sarcoma is present more in women between the ages of 14 and 82, mainly in the third and fourth decades of life. At diagnosis, as in other sarcomas, the size is bigger than 5 cm, with a direct correlation with prognosis; because of few data in literature due to its inciden
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