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Journal articles on the topic 'Patients with Osteoarthritis'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

ten Berg, Paul W. L., Erik Heeg, Simon D. Strackee, and Geert J. Streekstra. "Joint Space Narrowing in Patients With Pisotriquetral Osteoarthritis." HAND 12, no. 5 (2016): 490–92. http://dx.doi.org/10.1177/1558944716677542.

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Background: Patients with suspected pisotriquetral osteoarthritis may show joint space narrowing. However, the extent of joint space narrowing and its deviation from the joint space width (JSW) in normal anatomy is unknown. In this pathoanatomic study, we therefore compared the JSW in the pisotriquetral joint between osteoarthritic patient wrists and healthy wrists. Methods: We reviewed preoperative computed tomography (CT) scans of 8 wrists of patients with ulnar-sided wrist pain who underwent a pisiformectomy with confirmed pisotriquetral osteoarthritis at surgery. We also reviewed CT scans

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Zholdoshova, Aigul. "The Relationship between Osteoarthritis and Osteoporosis in Patients with Primary Generalized Osteoarthritis." Turkish Journal of Rheumatology 28, no. 3 (2013): 163–72. http://dx.doi.org/10.5606/tjr.2013.2984.

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Reeni.D, Bijilin, and George Joe Kumar. A. "A Study to Evaluate the Effectiveness of Aloe Vera Gel on Pain Perception among Patients with Osteoarthritis at Selected Communities in Kanyakumari District." Galore International Journal of Applied Sciences and Humanities 5, no. 4 (2021): 54–60. http://dx.doi.org/10.52403/gijash.20211009.

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Aim: to evaluate the effectiveness of Aloe Vera gel on pain perception among patients with osteoarthritis in selected communities at Kanyakumari district. Objectives: (i) To assess and compare the pre-test and post-test level of pain perception among patients with osteoarthritis in experimental and control group. (ii) To evaluate the effectiveness of Aloe Vera gel on level of pain perception among patients with osteoarthritis in experimental group. (iii) To find out the association between the post-test level of pain perception among patients with osteoarthritis in experimental group and contr

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4

Rahman, Kharman Khidhr, Shahen Ali Ahmed, Sarkawt Hamad Ali, and Khoshee Salh Hamed. "Detection and Severity Assessment of Temporomandibular Joint Osteoarthritic Changes in Patients with Temporomandibular Disorders Using CBCT." Erbil Dental Journal 7, no. 2 (2024): 132–43. https://doi.org/10.15218/edj.2024.15.

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Background and objectives: Osteoarthritis refers to a non-inflammatory condition often linked to aging. It involves the gradual breakdown of bone, cartilage, and surrounding soft tissues around the joints. The aim of this study is to detect osteoarthritic change in patients with temporomandibular disorder, to determine the severity of osteoarthritic changes, and to assess the relation of gender and age with the severity prevalence of temporomandibular joint osteoarthritis. Material and method: This retrospective, cross-sectional study analyzed 100 cone beam computed tomography (CBCT) scans of

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Waraich, Harsimrat S., Vikas Kumar, Ashok Goel, and Jatinder Singh. "A comparative study to assess the safety and efficacy of etoricoxib versus aceclofenac in osteoarthritis." International Journal of Basic & Clinical Pharmacology 7, no. 10 (2018): 2010. http://dx.doi.org/10.18203/2319-2003.ijbcp20183939.

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Background: Osteoarthritis (OA) is most common form of arthritis; also referred as degenerative joint disease or “wear and tear” arthritis. Cyclooxygenase-2 (COX-2) inhibitors are effective for pain and inflammation in OA and gained importance over conventional non-steroidal anti-inflammatory agents (NSAIDs), as causes significantly less toxicity, particularly, in gastrointestinal tract. The objective of the present research was to study the short-term comparative clinical efficacy of aceclofenac and etoricoxib in patients with osteoarthritis and to compare the safety profile of the two drugs

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Gong, H. S., and K. J. Bae. "FRI0402 MAGNETIC RESONANCE IMAGING EVALUATION OF CARTILAGE EROSION AND LIGAMENT INTEGRITY IN EARLY STAGE THUMB CARPOMETACARPAL JOINT OSTEOARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 799.3–799. http://dx.doi.org/10.1136/annrheumdis-2020-eular.878.

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Background:Most of the studies on pathogenesis of thumb carpometacaral joint (CMCJ-1) osteoarthritis were from cadavers or patients with advanced osteoarthritis, therefore the findings may not reflect any early changes of cartilage wear and ligament condition.Objectives:We evaluated MRI to address where articular degeneration begins and which ligaments are most often involved in the early clinical stage CMCJ-1 osteoarthritis.Methods:We retrospectively analyzed MRI examinations of 26 patients with early clinical stage CMCJ-1 osteoarthritis without radiologic abnormality and 19 control patients

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Hina, Peraha Wagan, Dr Suni Kumar, Muhammad Tahir Akram, Chaman Lal, and Dr Tanzeela Mujtaba. "Role of Joint Mobilization in Improving Function and Reducing Pain in Knee Osteoarthritis Patients." ACADEMIA International Journal for Social Sciences 4, no. 2 (2025): 1695–713. https://doi.org/10.63056/acad.004.02.0283.

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Knee osteoarthritis is a degenerative disease of articular cartilage and effect on joint mobility and balance. Mobilization is passive manual therapy which is perform by skill practitioner in order to reduce initial symptoms like pain, swelling, and improve range of motion and joint mobility. The current study investigated the outcomes of Mobilization in knee osteoarthritis patient.The objective of this study is to evaluate Outcomes of knee Mobilization in knee Osteoarthritis.A total of 100 subject were recruited for the study on the basis of inclusion and exclusion criteria after signing the

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Wang, Lejun, and Yuping Cao. "A Study on the Rehabilitation of Patients with Osteoarthritis of the Knee." Journal of Clinical Medicine Research 5, no. 1 (2024): 47. http://dx.doi.org/10.32629/jcmr.v5i1.1783.

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Rehabilitation refers to the integrated and coordinated use of various means, such as medical, educational, social and occupational, to restore the patient's physical and psychological injuries caused by accidents or sports injuries as far as possible and to the maximum extent possible, so that his or her physical, psychological and social adaptation can be maximally rehabilitated. Osteoarthritis of the knee is one of the osteoarthritic diseases, which is characterised by chronic, long-term pain in the affected area and degenerative changes in the function of the affected limb, and also has th

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Yang, Tzi-Peng, Hsiao-Mei Chen, Chao-Chin Hu, et al. "Interaction of Osteoarthritis and BMI on Leptin Promoter Methylation in Taiwanese Adults." International Journal of Molecular Sciences 21, no. 1 (2019): 123. http://dx.doi.org/10.3390/ijms21010123.

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Leptin (LEP) regulates glucose metabolism and energy storage in the body. Osteoarthritis (OA) is associated with the upregulation of serum LEP. LEP promoter methylation is associated with obesity. So far, few studies have explored the association of BMI and OA with LEP methylation. We assessed the interaction between body mass index (BMI) and OA on LEP promoter methylation. Data of 1114 participants comprising 583 men and 558 women, aged 30–70 years were retrieved from the Taiwan Biobank Database (2008–2015). Osteoarthritis was self-reported and cases were those who reported having ever been c

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Swärd, Elin, Inger Nennesmo, and Maria Wilcke. "Structural Changes in the Posterior Interosseous Nerve from Patients with Wrist Osteoarthritis and Asymptomatic Controls." Journal of Wrist Surgery 9, no. 06 (2020): 481–86. http://dx.doi.org/10.1055/s-0040-1713655.

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Abstract Background Posttraumatic morphological changes have been described in the posterior interosseous nerve (PIN) after mild wrist trauma, and it has been suggested that posttraumatic nerve changes may contribute to wrist pain. PIN excision has shown to relieve pain in some patients with wrist osteoarthritis. However, is not known if PINs from osteoarthritic wrist have pathological features. Objective The aim of this study was to investigate whether PINs from osteoarthritic wrists show morphological changes that are not present in healthy wrists. Materials and Methods PINs resected from 15

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Rana, Priyanka, Shabnam Joshi, and Monika Bodwal. "QUANTITATIVE GAIT ANALYSIS IN PATIENTS WITH KNEE OSTEOARTHRITIS." International Journal of Physiotherapy and Research 4, no. 5 (2016): 1684–88. http://dx.doi.org/10.16965/ijpr.2016.164.

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Purcell, Sarah, Robert Thornberry, Sarah A. Elliott, et al. "Body Composition, Strength, and Dietary Intake of Patients with Hip or Knee Osteoarthritis." Canadian Journal of Dietetic Practice and Research 77, no. 2 (2016): 98–102. http://dx.doi.org/10.3148/cjdpr-2015-037.

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Purpose: To describe body composition (fat mass (FM) and fat-free mass (FFM)), strength, and nutritional characteristics of patients with hip or knee osteoarthritis undergoing total joint arthroplasty. Methods: In this prospective pilot study, osteoarthritic patients underwent body composition assessment using bioelectrical impedance analysis, grip strength measurement, and completed a 24-h dietary recall during their pre-operative assessment. Results: Fifty-five patients were included (∼66% females, age 43–89 years). Mean ± SD body mass index (BMI) was 32.79 ± 6.48 kg/m2 and 62% were obese. C

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Ghaznavi, Samina, Aneela Altaf Kidwai, Farhat Bashir, and Mahfooz Alam. "OSTEOARTHRITIS;." Professional Medical Journal 24, no. 10 (2017): 1579–83. http://dx.doi.org/10.29309/tpmj/2017.24.10.713.

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Objectives: To determine the pattern of symptomatic and radiographicosteoarthritis in the urban population of Karachi. Data Source: Outpatient clinics. Design ofStudy: Cross sectional observational. Setting: Liaquat National Hospital, Karachi. Period:August 2015 till July 2016. Materials and Methods: Symptomatic patients belonging to bothgenders, aged ≥ 30 years, having clinical and radiographic osteoarthritis involving knee, hip,spine, hand, foot and shoulder were included. Diagnosis of knee osteoarthritis was based onAmerican College of Rheumatology criteria, whereas the diagnosis of other j

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CHOU, PEI-HSI, SHEN-KAI CHEN, YOU-LI CHOIA, SIU-WAI LEE, FONG-CHING SU, and TING-SHENG LIN. "BIOMECHANICAL ANALYSIS OF KNEE OSTEOARTHRITIS PATIENTS AFTER THE TREATMENT OF GLUCOSAMINE." Biomedical Engineering: Applications, Basis and Communications 15, no. 01 (2003): 32–37. http://dx.doi.org/10.4015/s1016237203000067.

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Osteoarthritis (OA) encompassed a large and heterogeneous number of disorders affecting joints and bones, which culminate in a joint failure. In general, OA can be defined as a degenerative disease characterized by biomechanical and architectural deteriorations of the articular cartilage. After the age of 60 years, more than 80% of the people have radiological signs of OA in the knee, and 20% of the people suffer from pain and movement limitations. Currently used pharmacologic treatments, including acetaminophen and nonsteroidal anti-inflammatory drugs, do not slow or reverse the degenerative

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Jones, Mark, Riki Patel, Leena Adamian, et al. "Minimally Invasive Interventional Management of Osteoarthritic Chronic Knee Pain." Journal of Knee Surgery 32, no. 01 (2018): 072–79. http://dx.doi.org/10.1055/s-0038-1676071.

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AbstractChronic knee pain is a widely prevalent issue that can have a significant impact on a patient's quality of life. One of the leading causes of chronic knee pain is osteoarthritis. Total knee replacement is often the last and definitive resort for patients with severe symptomatic osteoarthritis after trial of less invasive interventions with failure to achieve symptomatic relief. Intra-articular injections are a mainstay of adjunctive conservative management and have demonstrated efficacy in reducing pain. Radiofrequency treatment is a viable option for poor surgical candidates, or for p

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Butarbutar, John, Mirna Phandu, Kevin Lee, Earlene Tasya, and Wendell Sebastian Sulaeman. "Ultrasound-guided Genicular Nerve Ablation with Alcohol Solution for Knee Osteoarthritis: A Case Series." Medicinus 11, no. 2 (2023): 69. http://dx.doi.org/10.19166/med.v11i2.7531.

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<div class="WordSection1"><p>Genicular nerve ablation using radiofrequency (RF) is a common minimally invasive procedure for painful osteoarthritic knees. However, the high cost and unavailability of equipment in many healthcare centers made this inconvenient for some patients. Some case reports tried the cheaper and newer method, using an alcohol solution to ablate the genicular nerves, showing considerable improvement in the patient's pain, functional knee score, and quality of life. We have attempted the ultrasound-guided genicular nerve ablation using alcohol solution in 6 pati

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Mabey, Thomas, and Sittisak Honsawek. "Role of Vitamin D in Osteoarthritis: Molecular, Cellular, and Clinical Perspectives." International Journal of Endocrinology 2015 (2015): 1–14. http://dx.doi.org/10.1155/2015/383918.

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Osteoarthritis is a debilitating and degenerative disease which affects millions of people worldwide. The causes and mechanisms of osteoarthritis remain to be fully understood. Vitamin D has been hypothesised to play essential roles in a number of diseases including osteoarthritis. Many cell types within osteoarthritic joints appear to experience negative effects often at increased sensitivity to vitamin D. These findings contrast clinical research which has identified vitamin D deficiency to have a worryingly high prevalence among osteoarthritis patients. Randomised-controlled trial is consid

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Iftikhar, Usman, Farooq Islam, Gulraiz Enderyas, et al. "Assessment of Quality of life among patients with hip osteoarthritis." Pakistan Journal of Medical and Health Sciences 16, no. 10 (2022): 81–84. http://dx.doi.org/10.53350/pjmhs22161081.

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Aim: To assess quality of life in patients with hip osteoarthritis. Method: A hospital based cross sectional study was carried out involving hip osteoarthritic patients at District headquarter hospital Gujranwala. From May 2022 to Sep 2022.A total of 196 participants were included in the study. Data were collected from the patients who met the inclusion/exclusion criteria and were entered and analyzed in (SPSS) software version 24.36-Item (SF-36) was used to collect data from participants. Results: The results of the study showed that overall poor quality of life with mean scores physical func

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Scimeca, Manuel, Elena Bonanno, Eleonora Piccirilli, et al. "Satellite Cells CD44 Positive Drive Muscle Regeneration in Osteoarthritis Patients." Stem Cells International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/469459.

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Age-related bone diseases, such as osteoarthritis and osteoporosis, are strongly associated with sarcopenia and muscle fiber atrophy. In this study, we analyzed muscle biopsies in order to demonstrate that, in osteoarthritis patients, both osteophytes formation and regenerative properties of muscle stem cells are related to the same factors. In particular, thanks to immunohistochemistry, transmission electron microscopy, and immunogold labeling we investigated the role of BMP-2 in muscle stem cells activity. In patients with osteoarthritis both immunohistochemistry and transmission electron mi

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Cakar, Murat, Semih Ayanoglu, Haluk Cabuk, Metin Seyran, Suleyman Semih Dedeoglu, and Hakan Gurbuz. "Association between vitamin D concentrations and knee pain in patients with osteoarthritis." PeerJ 6 (April 24, 2018): e4670. http://dx.doi.org/10.7717/peerj.4670.

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Objectives Osteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations of vitamin D and osteoarthritic knee pain. Subjects and Methods Vitamin D concentrations were measured with the 25 hydroxyvitamin D test in patients presenting with clinical symptoms of primary knee osteoarthritis. Osteoarthritis was graded on the Kellgren-Lawrence grading scale from anteroposterior and lateral radiographs. Height, weigh

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Çakar, Murat, Semih Ayanoğlu, Haluk Çabuk, Metin Seyran, Süleyman Semih Dedeoğlu, and Hakan Gürbüz. "Association between Vitamin D Concentrations and Knee Pain in Patients with Osteoarthritis." Orthopaedic Journal of Sports Medicine 5, no. 2_suppl2 (2017): 2325967117S0008. http://dx.doi.org/10.1177/2325967117s00083.

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Objectives: Osteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations of vitamin D and osteoarthritic knee pain. Subjects and Methods: Vitamin D concentrations were measured with the 25 hydroxyvitamin D test in patients presenting with clinical symptoms of primary knee osteoarthritis. Osteoarthritis was graded on the Kellgren-Lawrence grading scale from anteroposterior and lateral radiographs. Height, wei

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Abd El-Karim, Somaia S., Ahlam H. Mahmoud, Asmaa K. Al-Mokaddem, et al. "Development of a New Benzofuran–Pyrazole–Pyridine-Based Molecule for the Management of Osteoarthritis." Molecules 28, no. 19 (2023): 6814. http://dx.doi.org/10.3390/molecules28196814.

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Osteoarthritis is a substantial burden for patients with the disease. The known medications for the disease target the mitigation of the disease’s symptoms. So, drug development for the management of osteoarthritis represents an important challenge in the medical field. This work is based on the development of a new benzofuran–pyrazole–pyridine-based compound 8 with potential anti-inflammatory and anti-osteoarthritis properties. Microanalytical and spectral data confirmed the chemical structure of compound 8. The biological assays indicated that compound 8 produces multifunctional activity as

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El Mansouri, N., T. Fatima Zahrae, R. Bensaid, et al. "AB1577-PARE DO MOROCCAN PATIENTS DISCUSS WITH THEIR RHEUMATOLOGISTS ABOUT DIET AS PART OF THE MANAGEMENT OF THEIR OSTEOARTHRITIS?" Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1887.2–1887. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4836.

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BackgroundThe question of diet is frequently asked by patients with osteoarthritis. Beyond the effect of weight on the worsening of their symptoms, patients often ask whether certain foods, labelled as inflammatory or anti-inflammatory, can improve or worsen their disease.ObjectivesThe aim of our study is to find out whether patients with osteoarthritis discuss diet during their medical visits and to investigate the association between patients’s reported dietary beliefs and practices and their willingness to discuss them.MethodsThis is a survey based on a questionnaire that included all patie

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Bagge, Eva, and Peter Brooks. "Osteoarthritis in Older Patients." Drugs & Aging 7, no. 3 (1995): 176–83. http://dx.doi.org/10.2165/00002512-199507030-00003.

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Liu, R., WY Kwok, TPM Vliet Vlieland, et al. "Mortality in osteoarthritis patients." Scandinavian Journal of Rheumatology 44, no. 1 (2014): 70–73. http://dx.doi.org/10.3109/03009742.2014.922213.

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Munthe, Ronald Vinantius, Wendy Hendrika, and Natasya Yoreskitha Gurusinga. "Relationship between Body Mass Index (BMI) and Knee Osteoarthritis at the UKI General Hospital, Jakarta in 2017." International Journal of Health Sciences and Research 11, no. 10 (2021): 365–77. http://dx.doi.org/10.52403/ijhsr.20211047.

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Knee osteoarthritis is a degenerative joint disease usually suffered by elderly patients, contributing to the high risk of disability. The risk factors that affect the severity of knee osteoarthritis are obesity, age, sex, occupation, patient's history of the disease, trauma and other factors. Excessive body weight is a factor that exacerbates the disease of Osteoarthritis. Generally, this research is aimed to examine the correlation between Body Mass Index (BMI) and knee osteoarthritis at UKI General Hospital in 2017. The researcher used a descriptive-analytic study with a cross-sectional app

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ten Berg, P. W. L., J. G. G. Dobbe, M. E. Brinkhorst, S. D. Strackee, and G. J. Streekstra. "Comparing radial styloid size between osteoarthritic and healthy wrists: a pathoanatomical three-dimensional study." Journal of Hand Surgery (European Volume) 42, no. 1 (2016): 63–70. http://dx.doi.org/10.1177/1753193416669261.

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Radial styloid pointing due to spur formation is considered an early sign of osteoarthritis, but is sometimes difficult to distinguish from normal anatomic variation. In this pathoanatomical study we used three-dimensional imaging techniques to evaluate quantitatively whether the styloid size is larger in wrists with scaphoid non-union than in healthy wrists. We compared these findings with duration of the non-union and with the scaphoid non-union advanced collapse classification, which was based on radiographic assessment of the general level of wrist osteoarthritis. In 31 patients, the injur

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Szerb, Imre, Tamás Gál, Dániel Kiss, Viktória Nagy, and László Hangody. "Efficacy assessment of radiosynoviorthesis on the progression of radiological osteoarthritic features of hip and ankle joint in patients with osteoarthritis and rheumatoid arthritis." Nuklearmedizin 59, no. 03 (2020): 269–75. http://dx.doi.org/10.1055/a-1108-1187.

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Abstract Objective The study objective was to evaluate the long-term effect of radiosynoviorthesis (RSO) on the progression of radiological and nuclear-medical osteoarthritic features of hip and ankle joint in patients with osteoarthritis and rheumatoid arthritis. Patients and Methods The study included 89 hip joints of 81 patients, of which 48 had osteoarthritis (OA) and 33 had rheumatoid arthritis (RA). In terms of ankle joints, 64 patients were included of which 43 suffered from OA and 21 from RA. The mean follow-up time was 9.2 years for OA and 8.9 years for RA patients. Patients with RA w

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Long, L., and E. Ernst. "Homeopathic remedies for the treatment of osteoarthritis: a systematic review." British Homeopathic Journal 90, no. 01 (2001): 37–43. http://dx.doi.org/10.1054/homp.1999.0449.

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AbstractOsteoarthritis is a common rheumatic disease. Limitations of conventional medical management of this condition indicate a real need for safe and effective treatment of osteoarthritic patients. The authors review the clinical evidence for and against the effectiveness of homeopathic medicines in the treatment of patients with osteoarthritis. A systematic review of all randomised controlled clinical trials of homeopathic treatment of patients with this condition is presented. A comprehensive search yielded four trials which are discussed in detail. The authors conclude that the small num

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Kubal, Swati V., and Kshitija S. Ghole. "Correlation of Exercise Capacity with Functional Disability in Patients with Osteoarthritis of Knee." International Journal of Physiotherapy and Research 9, no. 4 (2021): 3883–87. http://dx.doi.org/10.16965/ijpr.2021.136.

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Introduction: Osteoarthritis of knee is a progressive joint disease which produces pain, inflammation and destruction of joint which in turn leads to range of motion limitation and walking disabilities. Affection in physical functioning is determined not only by just activities involving lower limb capacity but also by the activities which require use of upper extremities. Hence in this study, 6MWD and no. of rings moved in 6 minutes were taken as an outcome measures for determining the exercise capacity. KOOS is a self-administered questionnaire which was used in its cross culturally adapted

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Kim, Beom Suk. "Exercise for patients with arthritis." Journal of the Korean Medical Association 67, no. 9 (2024): 573–78. http://dx.doi.org/10.5124/jkma.2024.67.9.573.

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Background: Osteoarthritis and rheumatoid arthritis are major causes of pain and disability globally, and exercise is known to be effective at alleviating symptoms and improving physical function.Current Concepts: Knee osteoarthritis is a common degenerative disease, and comprehensive clinical practice guidelines have been established. Most studies strongly recommend appropriate weight management combined with exercise therapy. Aerobic, strength, resistance, isometric, neuromuscular, and balance training have been used. However, the current evidence is insufficient to recommend specific prescr

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J, Viswanath S. Sankaraiah* Chakrapani Cheekavolu Renu Dixit M. Naresh Kumar Simhadri V.S.D.N.A. Nagesh. "EFFECT OF TWO AYURVEDIC DRUGS ON SERUM CALCIUM LEVEL IN OSTEOARTHRITIS INDUCED RATS AND OSTEOARTHRITIS PATIENTS." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2057–61. https://doi.org/10.5281/zenodo.835057.

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Background: To evaluate the comparative study of serum calcium level after treatment of cissusquadrangularis linn and zingiber officinale rocs in osteoarthritis induced rats and osteoarthritis patients. Method: Estimation of serum calcium levels are before and after treatment of tested drugs in osteoarthritis rats and patients 1. Animal treated: Cissus quadrangularis linn-450 mg/kg orally; Zingiber officinale rocs-450 mg/kg orally; cissus quadrangularis linn+ zingiber officinale rocs-450mg/kg orally; 2.Patients treated: Cissus quadrangularis linn-5 gm; Zingiber officinale rocs-5 gm and Cissusq

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Welhaven, Hope D., Avery H. Welfley, Priyanka Brahmachary, et al. "Metabolomic Profiles and Pathways in Osteoarthritic Human Cartilage: A Comparative Analysis with Healthy Cartilage." Metabolites 14, no. 4 (2024): 183. http://dx.doi.org/10.3390/metabo14040183.

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Osteoarthritis (OA) is a chronic joint disease with heterogenous metabolic pathology. To gain insight into OA-related metabolism, metabolite extracts from healthy (n = 11) and end-stage osteoarthritic cartilage (n = 35) were analyzed using liquid chromatography–mass spectrometry metabolomic profiling. Specific metabolites and metabolic pathways, including lipid and amino acid pathways, were differentially regulated in osteoarthritis-derived and healthy cartilage. The detected alterations in amino acids and lipids highlighted key differences in bioenergetic resources, matrix homeostasis, and mi

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P. K., Navaneeth, Prakash Nayar S., and T. M. Jose. "Clinical and functional outcome of total knee arthroplasty in osteoarthritic patients at a tertiary care center in Kerala: a prospective study." International Journal of Advances in Medicine 9, no. 10 (2022): 1017. http://dx.doi.org/10.18203/2349-3933.ijam20222399.

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Background: Osteoarthritis affects the knee joint more frequently than any other joint. Osteoarthritis is a chronic joint disease that affects the older age group, women more frequently, and is associated in 90% of cases with a varus deformity of the knee. The following study was conducted to evaluate the functional outcome of total knee arthroplasty in osteoarthritis using the knee society score.Methods: The study was conducted in patients treated for osteoarthritis of the knee joint at Jubilee Mission Medical College and Research Institute, Thrissur, Kerala during the period from December 20

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Adrianto, Madyo, Anak Agung Pradnya Paramitha Vidiani, Anisa Nova Puspitaningrum, and Valentina Girsang. "Literature Review: Effectiveness of NSAIDs in Osteoarthritis Patients." Science and Community Pharmacy Journal 3, no. 2 (2024): 196–202. https://doi.org/10.63520/scpj.v3i2.582.

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Pain, stiffness, swelling, and decreased joint function are some of the clinical signs of osteoarthritis, a disease that affects numerous anatomical and physiological aspects of joint tissue, cartilage degradation, bone remodeling, and osteophyte development. This literature review's objective is to ascertain the efficacy of NSAIDs in osteoarthritis by searching for journals from PubMed.. The method used was to search for articles through pubmed using the keywords "NSAID", "osteoarthritis", "Therapy" with a filter added for the last 5 years (2019-2024) obtained 103 articles. Then with the keyw

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Kvarda, Peter, Lukas Heisler, Nicola Krähenbühl, et al. "3D Assessment in Posttraumatic Ankle Osteoarthritis." Foot & Ankle Orthopaedics 7, no. 1 (2022): 2473011421S0029. http://dx.doi.org/10.1177/2473011421s00295.

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Category: Ankle; Ankle Arthritis; Hindfoot; Other Introduction/Purpose: Auto-generated 3-dimensional (3D) measurements based on weightbearing cone-beam computed tomography (CT) scan technology may allow for a more accurate hind- and midfoot assessment. The current study evaluated the reliability and clinical relevance of such measurements in patients with posttraumatic end-stage ankle osteoarthritis. Methods: Seventy-two patients treated at our institution for posttraumatic end-stage ankle osteoarthritis, with available weightbearing conventional radiographs and a cone-beam CT scan, were analy

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Lluch Girbés, Enrique, Jo Nijs, Rafael Torres-Cueco, and Carlos López Cubas. "Pain Treatment for Patients With Osteoarthritis and Central Sensitization." Physical Therapy 93, no. 6 (2013): 842–51. http://dx.doi.org/10.2522/ptj.20120253.

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Osteoarthritis is one of the most frequent, disabling, and costly pathologies of modern society. Among the main aims of osteoarthritis management are pain control and functional ability improvement. The exact cause of osteoarthritis pain remains unclear. In addition to the pathological changes in articular structures, changes in central pain processing or central sensitization appear to be involved in osteoarthritis pain. The latter calls for a broader approach to the management of patients with osteoarthritis. Yet, the scientific literature offers scant information addressing the treatment of

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Novelyn, Silphia, and Ronald Vinantius Munthe. "Relationship between Body Mass Index and Knee Osteoarthritis at UKI General Hospital in 2017." Journal of Drug Delivery and Therapeutics 12, no. 4-S (2022): 154–62. http://dx.doi.org/10.22270/jddt.v12i4-s.5575.

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Knee osteoarthritis is a degenerative joint disease usually suffered by elderly patients, contributing to the high risk of disability. The risk factors that affect the severity of knee osteoarthritis are obesity, age, sex, occupation, patient's history of the disease, trauma, and other factors. Excessive body weight is a factor that exacerbates the disease of osteoarthritis. Generally, this research is aimed to examine the correlation between Body Mass Index (BMI) and knee osteoarthritis at UKI General Hospital. The researcher used a descriptive-analytic study with a cross-sectional approach.

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Rangasamy, Pradeep, Ajay Thangaraj, Premkumar Kamatchinathan, et al. "Assessment of Sleep Quality in Patients with Osteoarthritis." Journal of Evidence Based Medicine and Healthcare 7, no. 48 (2020): 2862–66. http://dx.doi.org/10.18410/jebmh/2020/586.

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BACKGROUND Sleep disturbances usually accompany osteoarthritis (OA) because of chronic pain. Poor sleep quality is related to many factors like pain, fatiguability, restless leg syndrome, immobility of joints, anxiety and depression. But the quality of the sleep in patients with osteoarthritis has been rarely studied. We wanted to assess the prevalence of sleep disturbances in OA patients, determine the sleep quality in osteoarthritis patients and evaluate the relationship between pains and sleep quality. METHODS 150 patients with osteoarthritis were selected through convenience sampling as pe

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Phalswal, Uma, Vandna Pandey, Ashok Kumar, and Abhay Elhence. "Correlation of knee society score and oxford knee score in patients with moderate to severe osteoarthritis of the knee." IP International Journal of Orthopaedic Rheumatology 7, no. 1 (2021): 17–23. http://dx.doi.org/10.18231/j.ijor.2021.005.

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Osteoarthritis (OA) of the knee is a degenerative, non-inflammatory joint condition marked by articular cartilage disintegration and the growth of new bone (osteophytes) at the joint surfaces and borders. It impairs one's ability to function and makes one disabled. It is the most common rheumatic disease. Because the Knee is a weight-bearing joint and a crutch joint, it is the most usually afflicted joint by Osteoarthritis.A Correlational study was conducted to find out the correlation between Knee Society Score (KSS) and Oxford Knee Score (OKS) on 142 Osteoarthritis Knees. Purposive sampling

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Valente, Catarina, Laura Haefliger, Julien Favre, and Patrick Omoumi. "Ossification of the acetabular rim: a highly prevalent finding in asymptomatic non-osteoarthritic hips of all ages." European Radiology 31, no. 9 (2021): 6802–9. http://dx.doi.org/10.1007/s00330-021-07750-y.

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Abstract Objective To estimate the prevalence of acetabular rim ossifications in the adult population with asymptomatic, morphologically normal hips at CT and to determine whether the presence of these ossifications is associated with patient- or hip-related parameters. Methods We prospectively included all patients undergoing thoracoabdominal CT over a 3-month period. After exclusion of patients with a clinical history of hip pathology and/or with signs of osteoarthritis on CT, we included a total of 150 hips from 75 patients. We analyzed the presence and the size of ossifications around the

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Ware, J. Kristopher, Brett D. Owens, Matthew R. Akelman, et al. "Preoperative KOOS and SF-36 Scores Are Associated With the Development of Symptomatic Knee Osteoarthritis at 7 Years After Anterior Cruciate Ligament Reconstruction." American Journal of Sports Medicine 46, no. 4 (2018): 869–75. http://dx.doi.org/10.1177/0363546517751661.

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Background: Anterior cruciate ligament (ACL) tears are associated with the development of knee osteoarthritis despite ACL reconstruction surgery. However, little evidence is available to determine which patients will develop symptomatic knee osteoarthritis. Purpose: To determine if preoperative outcome measures—KOOS (Knee injury and Osteoarthritis Outcome Score) and SF-36 (36-item Short Form Health Survey)—were associated with the development of a symptomatic knee 7 years after ACL reconstruction. A secondary goal was to examine the relationship between imaging evidence of knee osteoarthritis

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Cianni, Luigi, Emidio Di Gialleonardo, Donato Coppola, et al. "Current Evidence Using Pulsed Electromagnetic Fields in Osteoarthritis: A Systematic Review." Journal of Clinical Medicine 13, no. 7 (2024): 1959. http://dx.doi.org/10.3390/jcm13071959.

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(1) Background: Osteoarthritis (OA) significantly impacts patients’ quality of life and negatively affects public healthcare costs. The aim of this systematic review is to identify the effectiveness of pulsed electromagnetic fields (PEMFs) in OA treatment across different anatomical districts, determining pain reduction and overall improvement in the patient’s quality of life. (2) Methods: In this systematic review following PRISMA guidelines, PubMed and Google Scholar were searched for randomized controlled trials involving patients with osteoarthritis undergoing PEMF therapy. Seventeen studi

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COLVILLE, R. J. I., K. S. NICHOLSON, and H. J. C. R. BELCHER. "Hand Surgery and Quality of Life." Journal of Hand Surgery 24, no. 3 (1999): 263–66. http://dx.doi.org/10.1054/jhsb.1998.0211.

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The outcome in patients having surgery to the hand was assessed subjectively using a questionnaire that covered activities of daily living (ADL), hand pain and psychological well-being. The questionnaires were completed on average 6.9 months preoperatively and 20.6 months postoperatively by 15 patients with osteoarthritis undergoing trapeziectomy and 25 patients with rheumatoid arthritis undergoing Swanson arthroplasties of the metacarpophalangeal joints. Surgery resulted in significant improvements in reported ADL and hand pain, in both groups. Improvement in perception of hand function and h

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Villagrán-Andrade, Karla Mariuxi, Carmen Núñez-Carro, Francisco J. Blanco, and María C. de Andrés. "Nutritional Epigenomics: Bioactive Dietary Compounds in the Epigenetic Regulation of Osteoarthritis." Pharmaceuticals 17, no. 9 (2024): 1148. http://dx.doi.org/10.3390/ph17091148.

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Nutritional epigenomics is exceptionally important because it describes the complex interactions among food compounds and epigenome modifications. Phytonutrients or bioactive compounds, which are secondary metabolites of plants, can protect against osteoarthritis by suppressing the expression of inflammatory and catabolic mediators, modulating epigenetic changes in DNA methylation, and the histone or chromatin remodelling of key inflammatory genes and noncoding RNAs. The combination of natural epigenetic modulators is crucial because of their additive and synergistic effects, safety and therap

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Çıkım, Gürkan, and Ülkü Veranyurt. "EVALUATION OF HOMOCYSTEINE AND VITAMIN D LEVELS IN OSTEOARTHRITIS PATIENTS." e-Journal of New World Sciences Academy 16, no. 2 (2021): 68–73. http://dx.doi.org/10.12739/nwsa.2021.16.2.1b0109.

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Alamri, Shar A. "Exercises versus Manual Therapy in Elderly Patients with Knee Osteoarthritis." International Journal of Physical Education & Sports Sciences 13, no. 4 (2018): 13–21. http://dx.doi.org/10.29070/13/57567.

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Hamid, Mowaffak Mostafa Abd El, Noha Abd El Halim El Sawy, Abla Ahmed Abo Zeid, and ,. Riham Abdelmaksoud Hamed Abdelmaksoud. "PREVALENCE OF KNEE OSTEOARTHRITIS AMONG EGYPTIAN DIABETIC TYPE 2 PATIENTS." International Journal of Physiotherapy and Research 6, no. 2 (2018): 2654–59. http://dx.doi.org/10.16965/ijpr.2018.101.

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Noor, Kinza, Muhammad Aqdus Ahsan, Salma Bibi, and Tayyaba Mumtaz. "The Effectiveness of Aquatic Exercises in Improving Balance and Gait in Patients with Knee Osteoarthritis: A Systematic Review." Pakistan Journal of Medical and Health Sciences 17, no. 6 (2023): 416–22. http://dx.doi.org/10.53350/pjmhs2023176416.

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Aim: Knee osteoarthritis is a degenerative joint disease that primarily affects older persons. The second most common disease among adults living in communities is osteoarthritis, which also has the second-highest overall medical cost aggregate. Objective: This review aimed to synthesize evidence for the effectiveness of aquatic exercises on the mobility, balance, gait, and posture of patients with knee osteoarthritis. Method: The databases utilized for literature searching were Embase, PubMed, PEDro, Cochrane library, and web of science. The search was conducted for literature selection on el

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Li, C., Y. Ding, S. Li, S. Lin, Z. Wen, and Z. Ouyang. "TAK1 MEDIATES HMGB1-INDUCED MACROPHAGE ACTIVATION IN OSTEOARTHRITIS." Orthopaedic Proceedings 105-B, SUPP_7 (2023): 107. http://dx.doi.org/10.1302/1358-992x.2023.7.107.

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Osteoarthritis, the most common degenerative joint disease, significantly impairs life quality and labor capability of patients. Synovial inflammation, initiated by HMGB1 (High mobility group box 1)-induced activation of macrophage, precedes other pathological changes. As an upstream regulator of NF-κB (nuclear factor-kappa B) and MAPK (mitogen-activated protein kinase) signaling pathway, TAK1 (TGF-β activated kinase 1) participates in macrophage activation, while its function in osteoarthritis remains unveiled. This study aims to investigate the role of TAK1 in the pathogenesis of osteoarthri

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