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1

Kilpatrick, Kaylon Ann. "Starvation induces Polycystic Ovarian Syndrome (PCOS) like symptoms in Drosophila melanogaster." Thesis, Mississippi College, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10128977.

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<p> Polycystic Ovarian Syndrome (PCOS) is a metabolic and endocrine disorder that is the most common cause of infertility. PCOS can manifest itself as a long and short term disability and is characterized by insulin resistance (IR), hyperandrogenism, anovulation, hyperinsulinaemia and polycystic ovaries. Our lack of understanding of this disorder and its long term effects has complicated the treatment of the disorder; yet, it is clear that PCOS involves the intricate interaction between genetics, environments and behaviors. To study this disease, scientists have used various animal models. Sin
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2

Koivunen, R. (Riitta). "Endocrine and metabolic changes in women with polycystic ovaries and polycystic ovary syndrome." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514264266.

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Abstract The prevalence of the isolated ultrasonographic finding of polycystic ovaries (PCO) in the Finnish population and among women with a history of gestational diabetes (GDM) and changes in the present carbohydrate metabolism were investigated in the present study. One aim of this study was to investigate the prevalence of the recently discovered variant type LH (v-LH) in PCOS and to compare patient cohorts from Finland, the Netherlands, the United Kingdom and the United States of America. In addition, this study attempted to evaluate the nature of the ovarian streoidogenic respons
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3

Ellerman, Jennifer Lynn. "Don't Blame It on My Ovaries: Exploring the Lived Experience of Women with Polycystic Ovarian Syndrome and the Creation of Discourse." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4034.

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Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder among females of childbearing age, affecting between 6-8% of the population. It is also the most common cause of infertility. Females with PCOS may have two or more of a constellation of symptoms that can potentially leave them at odds in terms of normative ideals of femininity. This study examines how feminist theory interrogates and analyzes knowledge about the body and PCOS, integrating the lived experiences of women to provide a deeper, more meaningful understanding of what it means to be a woman with PCOS.
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4

Weidemann, Annchen. "The role of fructose restriction in addition to dietary modifications for weight loss and lifestyle improvement, on fertility outcome and other markers of metabolic syndrome (MS), in obese women with polycystic ovarian syndrome (PCOS)." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71878.

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Thesis (MNutr)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: The role of fructose restriction in addition to dietary modifications for weight loss and lifestyle improvement, on fertility outcome and other markers of metabolic syndrome, in obese women with polycystic ovarian syndrome (PCOS) Introduction: At the time at which the current study was undertaken no data, as yet, existed on whether restriction of fructose, while treating obese patients with PCOS for weight loss, improves the clinical symptoms and metabolic/anthropometric profile so as to promote fertility. Objectives: To eva
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5

McCook, Judy G., Nancy E. Reame, and Samuel S. Thatcher. "Health-Related Quality of Life Issues in Women with Polycystic Ovary Syndrome." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/7174.

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Objective: To evaluate the influence of obesity, fertility status, and androgenism scores on health-related quality of life in women with polycystic ovary syndrome (PCOS). Design: Cross-sectional, correlational. Setting: Private reproductive endocrinology practice in two southeast U.S. cities. Participants: Convenience sample of 128 women with PCOS, half of whom were attempting to conceive in addition to being treated for PCOS. Most were White (97%), married (78%), with a mean age of 30.4 years (SD ± 5.5). Main Outcome Measures: The Health-Related Quality of Life Questionnaire (PCOSQ) for wome
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6

Steinheim, Elena. "Effects of insulin sensitizing drug metformin on clinical features, endocrine and metabolic profiles in obese women with polycystic ovary syndrome." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2007. http://dx.doi.org/10.18452/15631.

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Metformineinnahme scheint reproduktive und metabolische Funktionen bei Frauen mit PCOS zu verbessern. Die zwiespältige aktuelle Studienlage kann bisher keine konkrete Aussage liefern, ob Metformin eine erfolgreiche therapeutische Möglichkeit des Syndroms darstellt. Ziel der vorliegenden randomisierten, placebo-kontrollierten Studie war es, die Auswirkung des antihyperglykämischen Medikaments Metformin in Kombination mit Ernährungsberatung und Sport auf übergewichtige Frauen mit PCOS zu ermitteln. Besondere Aufmerksamkeit galt der Wirkung des Medikaments hinsichtlich Insulin und Glukose-Stoffwe
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7

Patterson, Moneka Angilene. "Polycystic Ovary Syndrome Treatment." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4319.

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Polycystic ovary syndrome (PCOS) is an endocrine system disorder that affects women of reproductive age. If not treated properly, PCOS can lead to infertility. Lack of proper treatment of PCOS may also result in medical complications such as diabetes or heart disease. The rural clinic where this project took place did not have a mandatory guideline for treatment of PCOS; therefore, no standardized method of diagnosis or treatment of PCOS existed. The purpose of this project, guided by the IOWA evidence-based practice model, was to educate providers on the evidence-based guideline for diagnosis
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8

Alzanati, Nadia. "Polycystic ovarian syndrome and adipose tissue : contribution of peripheral androgen synthesis to hyperandrogenism in polycystic ovarian syndrome." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39390/.

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Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine, reproductive, metabolic and psychological disorder in women of childbearing age, affecting 6-10% of premenopausal women. Hyperandrogenism is the most important biochemical feature of the syndrome, which is responsible for the clinical features of PCOS, and is frequently associated with metabolic disturbance, such as insulin resistance, dyslipidaemia, glucose intolerance and hypertension, regardless of the presence of obesity. In several studies, attention has focused on androgen as the main factor for development of m
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9

Karlson, Johan, and Pernilla Vedenbrant. "Att leva med PCOS." Thesis, Linnéuniversitetet, Institutionen för hälso- och vårdvetenskap, HV, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-12004.

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Aim: To describe the lived experience of women with polycystic ovary syndrome (PCOS). Method: Eight scientific articles of appropriate quality were found, analyzed, condensed and synthesized. Different experiences by women with PCOS were found and ordered into themes. The findings were then anchored in associated literature and discussed. Results: Four different themes were found: Feeling different; Disturbing symptoms; Searching for answers; Care treatment. Each of these themes offered areas of improvement in regard to nursing care. Conclusions: Extra attention to the psychosocial aspects of
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10

McCook, Judy G., Beth A. Bailey, Stacey L. Williams, Sheeba Anand, and Nancy E. Reame. "Differential Contributions of Polycystic Ovary Syndrome (PCOS) Manifestations to Psychological Symptoms." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7172.

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The purpose of this study was to investigate the relative contributions of previously identified Polycystic ovary syndrome (PCOS) manifestations (infertility, hirsutism, obesity, menstrual problems) to multiple psychological symptoms. Participants were 126 female endocrinology patient volunteers diagnosed with PCOS who completed a cross-sectional study of PCOS manifestations and psychological symptoms. Participants had significantly elevated scores on nine subscales of psychological symptoms. Menstrual problems were significantly associated with all symptom subscales as well as the global indi
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11

Lindholm, Åsa Maria. "Metabolic Aspects in the Polycystic Ovary Syndrome." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-120235.

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Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of childbearing age and is associated with a number of metabolic disturbances. It has been hypothesised these women carry an increased risk of developing cardiovascular diseases (CVD) with advancing age. The first aim of this thesis was to establish the prevalence of PCOS-related symptoms in Northern Sweden. The Northern part of the WHO MONICA project was used for this purpose. Based on self-reported menstrual disturbances and hirsutism together with biochemical analyses of free androgen index, the estim
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12

Caldwell, Aimee Sarah Lee. "Unravelling The Role Of Androgens In Polycystic Ovary Syndrome." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18129.

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Polycystic Ovary Syndrome (PCOS) is a multifaceted hormonal disorder which affects 5-15% of reproductive-aged women worldwide. While classically recognised as an ovarian disorder, PCOS is associated with a variety of reproductive, endocrine and metabolic features including ovulatory dysfunction, infertility, hyperandrogenism, obesity, and an increased risk of type 2 diabetes mellitus and cardiovascular disease. The most consistently present of these is hyperandrogenism – supraphysiological levels of androgens such as testosterone (T) and dihydrotestosterone (DHT). Typically thought of as male
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13

Barry, John Anthony. "Exploration of biological causes of psychological problems in polycystic ovary syndrome (PCOS)." Thesis, City University London, 2011. http://openaccess.city.ac.uk/11666/.

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Background: Polycystic ovary syndrome (PCOS) affects up to 10% of women, and is characterised by elevated testosterone (T) levels. Women with PCOS have higher scores than healthy women on a range of measures of psychological problems. Objective: To test the hypotheses that: 1/ The female fetus in a PCOS pregnancy experiences elevated T levels; 2/ T causes mood disturbance in women with PCOS. 3/women with PCOS show more signs of mood disturbance typical of symptoms of reactive hypoglycaemia than healthy controls. Design: Mainly between-groups cross-sectional studies. Also two meta-analyses. Set
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14

Hudecova, Miriam. "Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-123248.

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Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. The overall risk of developing type 2 diabetes and impaired glucose tolerance (IGT) is three- to sevenfold higher in PCOS women, and the onset of glucose intolerance seems to occur at an earlier age than in healthy controls. Women with PCOS also have several risk factors for cardiovascular dis
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15

Marsden, Philippa Jane. "Insulin action and ovarian function in polycystic ovary syndrome." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313272.

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16

Badji, Aisha. "A PCOS-like Drosophila Melanogaster model." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-17845.

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Polycystic ovary syndrome (PCOS) is a female endocrine disorder defined by high androgen levels and presence of polycystic ovaries. PCOS is characterized by menstrual irregularities, anovulation, infertility, hyperandrogenism, insulin resistance, abdominal obesity, chronic inflammation and increased hair growth. The diagnosis is based on 2003/2004 Rotterdam criteria, which is based on the presence of the following phenotypes: anovulation, clinical and biochemical marks of hyperandrogenism and polycystic ovarian morphology. Theoretical causes could be genetical, environmental or maternal imprin
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17

Williams, Sophie. "The impact of Polycystic Ovary Syndrome (PCOS) on quality of life : exploration, measurement and intervention." Thesis, University of Derby, 2016. http://hdl.handle.net/10545/620535.

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Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders amongst women, estimated to affect one out of 10 women. Symptoms include infertility, obesity, alopecia, acne, hirsutism and menstrual irregularities. Women with the syndrome are also more likely to experience co-morbid physical and psychological conditions such as diabetes, heart disease, endometrial cancer and also depression and anxiety. PCOS has also been found to have a negative impact on quality of life. This thesis aimed to further understanding, and improve quality of life of women with PCOS in the UK. To ac
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18

Ding, Tao. "Epidemiological investigation and economic analysis of Polycystic Ovary Syndrome (PCOS) for women in the UK." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10045238/.

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BACKGROUND: Polycystic ovary syndrome (PCOS) is an endocrine disorder affecting millions of women worldwide. The pathophysiology of this condition is unclear but is believed to be caused by some genetic and environmental factors. PCOS is associated with a range of reproductive, metabolic and dermatological disorders and therefore, the economic burden of this condition can be potentially significant for the public health system in the UK. METHODS: The methodology used for this research includes several parts. Firstly, I conducted literature reviews to identify studies reporting the prevalence o
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19

Siemienowicz, Katarzyna Joanna. "Fetal programming of adult disease : causes and consequences of metabolic dysregulation in an ovine model of PCOS." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/28977.

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Polycystic ovary syndrome (PCOS) is a common and complex endocrine condition with reproductive and metabolic complications, affecting up to 10% of reproductive-age women. Hyperandrogenemia, ovulatory dysfunction, and luteinising hormone hypersecretion are characteristic traits of PCOS however, it seems that the most concerning long-term key issues are metabolic problems associated with the syndrome, such as hyperinsulinemia, insulin resistance, obesity, dyslipidaemia and non-alcoholic liver disease. Despite the numerous studies on PCOS, its origin and pathophysiology are still not fully unders
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20

McCook, Judy G., Stacey Williams, Beth Bailey, Sheeba Anand, and Nancy Reame. "Differential Contributions of the Reproductive and Metabolic Features of Polycystic Ovary Syndrome (PCOS) to Psychological Symptoms." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/7183.

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Objective: Although women with PCOS have elevated levels of psychological distress, findings regarding which aspects of PCOS contribute to psychological symptoms are inconsistent. The purpose of this study was to investigate the independent and differential contributions of the previously identified key PCOS manifestations (infertility, hirsutism, obesity, menstrual problems) to multiple psychological symptoms. Methods: Participants were 126 endocrinology patient volunteers diagnosed with PCOS who completed a cross-sectional study of key manifestations of PCOS (including the PCOSQ) and psychol
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21

McCook, Judy G., Stacey Williams, Beth Bailey, Sheeba Anand, Nancy Reame, and Samuel Thatcher. "Differential Contributions of the Reproductive and Metabolic Features of Polycystic Ovary Syndrome (PCOS) to Psychological Symptoms." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/7184.

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Objective: Although women with PCOS have elevated levels of psychological distress, findings regarding which aspects of PCOS contribute to psychological symptoms are inconsistent. The purpose of this study was to investigate the independent and differential contributions of the previously identified key PCOS manifestations (infertility, hirsutism, obesity, menstrual problems) to multiple psychological symptoms. Methods: Participants were 126 endocrinology patient volunteers diagnosed with PCOS who completed a cross-sectional study of key manifestations of PCOS (including the PCOSQ) and psychol
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22

Hamilton, Angela M. "The Relationship of Food Insecurity to Health Parameters in Adult Women with Polycystic Ovary Syndrome (PCOS)." Ohio University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1417013554.

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23

Mimouni, Nour El Houda. "Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome (PCOS) in adulthood." Thesis, Lille, 2019. http://www.theses.fr/2019LILUS051.

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Le syndrome des ovaires polykystiques (SOPK) est la principale cause d’infertilité feminine à travers le monde, associé à un risqué élevé de comorbidités avec des conséquences économiques non négligeables. Ce syndrome est caractérisé par une oligo-anovulation, une hyperandrogénie, et un aspect échographique d’ovaires polykystiques. De plus, la plupart des femmes atteintes de SOPK présentent des concentrations élevées de LH suggérant une libération accrue de GnRH. De plus, les patientes SOPK ont habituellement des concentrations en Hormone Anti Müllerienne (AMH) 2 à 3 fois plus élevés que les f
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24

Desjardins, G. Clarissa (Gina Clarissa). "Role of the hypothalamic opioid system in estradiol-induced polycystic ovarian syndrome." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41015.

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The intrahypothalamic distribution of mu, delta and kappa opioid receptor types was examined by in vitro radioautography using the opioid ligands $ sp{125}$I-FK-33 824, $ sp{125}$I-DTLET and $ sp{125}$I-DPDYN, respectively as selective markers. The density and distribution of these receptors in the hypothalamus of normal rats was then compared to that of rats injected with estradiol valerate in order to verify the location of the described increase in $ sp3$H-naloxone binding and to identify the specific opioid receptor type involved. Analysis of opioid receptor changes following long-term exp
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Hogg, Kirsten. "Novel approaches to the development and assessment of an ovine model of polycystic ovary syndrome." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5916.

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Polycystic ovary syndrome (PCOS) is a common reproductive, endocrine and metabolic disorder present in women of reproductive age. Despite the widespread prevalence and heritability of PCOS, the heterogeneous and polygenic traits have made the successful identification of candidate genes difficult. Animal models have been developed on the premise that early exposure to sex steroids can programme epigenetic changes that predispose the fetus to the adult features of PCOS. Past research has modelled ovarian dysfunction, endocrine abnormalities and metabolic perturbances in rodent, non-human primat
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Brotherton, Emily J. "Vascular and Haemorheological Responses following Acute Exercise in Lean and Active women with Polycystic Ovary Syndrome." Thesis, Griffith University, 2019. http://hdl.handle.net/10072/389734.

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Polycystic Ovary Syndrome (PCOS) is associated with an increased risk of cardiovascular disease (CVD), which is suggested to be largely due to vascular endothelial dysfunction. Endothelial dysfunction is typically represented as an impaired vasodilatory response to an appropriate shear stimulus which is dictated by the flow of blood and its components as well as vessel diameter. Notably, both vascular and haemorheological parameters have been well-documented to improve following long-term exercise in many disease states that share similar characteristics to PCOS. As such, high levels of cardio
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Rautio, K. (Katriina). "Effects of insulin-lowering drugs in PCOS: endocrine, metabolic and inflammatory aspects." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:951428268X.

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Abstract Most women with polycystic ovary syndrome (PCOS) exhibit features of metabolic syndrome, including insulin resistance, abdominal obesity, dyslipidaemia, glucose intolerance and low-grade chronic inflammation, reflected in elevated levels of serum C-reactive protein (CRP), placing these women at increased risk of cardiovascular disease and type 2 diabetes (type 2 DM). The aim of this study was to investigate the effects of two well-known insulin-lowering drugs used in the treatment of type 2 DM, metformin and rosiglitazone, on traditional cardiovascular risk factors and inflammation i
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Wang, Qi. "Chemerin and Prohibitin in the Regulation of Ovarian Follicular Development and their Potential Involvement in Polycystic Ovarian Syndrome." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24098.

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Follicular growth and maturation are tightly regulated processes, which involve the participation of endocrine, autocrineparacrine factors and intracellular molecules. Due to the numerous research efforts, a large number of regulators and their mechanisms of regulation of follicular growth and differentiation have been established. Although the abnormal expression and activities of some of these regulators are believed to be associated with ovarian dysfunction diseases, such as polycystic ovarian syndrome (PCOS), the etiology and pathogenesis of this syndrome are not completely understood. In
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Samino, Gené Sara. "Mass spectrometry and nuclear magnetic resonance based metabolomics applied to the study of polycystic ovary syndrome." Doctoral thesis, Universitat Rovira i Virgili, 2013. http://hdl.handle.net/10803/128209.

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Objectives: Three objectives of this thesis have been: (i) Mastering of the main analytical platforms used in metabolomics, (ii) Developing an untargeted metabolomic workflow, involving novel aspects of sample preparation, and data processing for metabolite identification, (iii) Implementing our untargeted metabolomic workflow to the study of human patients with Polycystic Ovary Syndrome (PCOS) and their response to drug treatment Results: In Work 1: Optimization metabolite extraction conditions for NMR analysis, followed by LC/ESI-MS by using the same sample extract with no need for solve
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Sprung, Victoria Spencer. "The impact of obesity and fitness on endothelial function in polycystic ovarian syndrome." Thesis, Liverpool John Moores University, 2012. http://researchonline.ljmu.ac.uk/6119/.

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Polycystic ovarian syndrome (PCOS) is a highly prevalent heterogeneous syndrome associated with abdominal obesity, insulin resistance and the metabolic syndrome. This clustering of risk factors could translate into an adverse cardiovascular disease (CVD) risk profile. Endothelial dysfunction, an early barometer of CVD, has been exhibited by women with PCOS; however, it remains unclear whether endothelial dysfunction is independent of CVD risk factors in this population. Exercise training has been found to enhance conduit artery and cutaneous microvessel endothelial function in various populati
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Shwarz, Michelle. "Addressing Polycystic Ovary Syndrome in Outpatient Mental Health Practices: A Brief Intervention to Increase Awareness." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/326149.

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Public Health<br>Ph.D.<br>Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting up to 18% of all women, yet only 1.5% have been formally diagnosed. Untreated, PCOS is associated with the early onset of diabetes mellitus type II, heart disease, and cancer. One of the most common clinical symptoms of PCOS is mental health illness. The estimated lifetime prevalence of mental illness in women with PCOS is 80%. Therefore, mental health professionals may be especially poised to screen, refer, and address PCOS in their practices. This study was used to develop a survey tool
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Edelstein, Sascha. "Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/10437.

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Includes bibliographical references (leaves 60-65).<br>Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy in women of reproductive age, affecting 5-10% of women in the general population. Patients present with menstrual disturbances, infertility and clinical hyperandrogenism. While the pathophysiology is not completely delineated, a strong familial association has been demonstrated, suggesting a genetic component. From January 2007 until February 2009, a total of 83 probands were recruited from the Gynaecological Endocrinology Clinic (GEC) at GSH. These were all women with PCOS a
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Tyndall, Victoria. "Androgens and the ovary." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5591.

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Between 10-15% of women suffer from polycystic ovary syndrome (PCOS), making it the most common cause of female infertility. Clinical features of PCOS include high circulating levels of ovarian androgens (T and A4), anovulation and obesity. The aetiology of this reproductive endocrinopathy is likely to be multifactorial, through the interplay of genetics, epigenetics and environmental factors. Primate research into sexual behaviour development noted that fetally androgenised monkeys developed symptoms like those of PCOS. There are now multiple animal models of PCOS using primates, sheep, rats
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El, Mahdi E. "Studies to investigate a possible association between Polycystic Ovary Syndrome and Epithelial Ovarian Cancer." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1397057/.

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Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders, affecting 5 % to 10 % of women of reproductive age. The Syndrome is associated with Type II diabetes and endometrial carcinoma but an association with epithelial ovarian cancer has also been suggested. The studies described in this thesis were designed to investigate this association at population, cellular and molecular levels. In the first study, a cross sectional questionnaire survey was conducted of 121 women aged between the ages of 20 and 40, with or without PCOS. Analysis of the replies from 52 women with
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Al-Mizyen, Ebtisam S. S. "Unilateral versus bilateral laparoscopic ovarian diathermy in the management of infertile women with clomiphene citrate resistant polycystic ovarian syndrome." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538365.

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36

Konecki, Angela. "A Retrospective Analysis of the Effect Weight Loss and Metformin use in Polycystic Ovarian Syndrome." The University of Arizona, 2006. http://hdl.handle.net/10150/624469.

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Class of 2006 Abstract<br>Objectives: To determine if Polycystic Ovarian Syndrome (PCOS) patients treated with lifestyle changes and metformin resulted in ovulation after six months of treatment. Methods: A retrospective chart review of initial patient visits at an infertility clinic were obtained. Patients that were given a diagnosis of PCOS were further reviewed for age at initial diagnosis, weight, height, ovarian cysts, lifestyle recommendations (diet, exercise, and vitamin use), metformin recommendations and usage, and if ovulation occurred after six months of treatment. Results: A tota
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Nilsson, Hedvig, and Nikolina Trlin. "Symtomen som begränsar livet : Kvinnors upplevelser och erfarenheter av att leva med polycystiskt ovarialsyndrom (PCOS)." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-41316.

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Polycystic ovary syndrome (PCOS) is a chronic condition that affects 6-18 % of all fertile women, PCOS manifests itself through various clinical symptoms, such as hirsutism and obesity. It is also a contributing factor to irregular menstrual cycles, which has an impact on life and future pregnancies. The aim of the literature study was to describe the experiences of women living with PCOS. A systematic literature review was conducted, which resulted in the selection of ten scientific articles. The result of the study is based on three categories: The women’s self-image, the women’s physical an
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Edelstein, Sascha. "The impact of body mass index (BMI) on metabolic and endocrine parameters in women with the polycystic ovary syndrome (PCOS)." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/3042.

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39

Ollila, M. M. (Meri-Maija). "The role of polycystic ovary syndrome (PCOS) and overweight/obesity in women’s metabolic and cardiovascular risk factors and related morbidities." Doctoral thesis, Oulun yliopisto, 2019. http://urn.fi/urn:isbn:9789526222592.

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Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting reproductive aged women, with reproductive, metabolic and cardiovascular implications across the life span. The typical features of PCOS include irregular menstruation, androgen excess and polycystic ovaries in ultrasonography. The majority of women with PCOS are overweight or obese, and, at least partly, obesity-driven metabolic abnormalities often coexist with PCOS. Despite intensive research, it has remained unclear whether PCOS per se is a risk factor of metabolic abnormalities, and cardiovascular dis
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Siebert, T. I. "A study of different clinical and biochemical parameters in polycystic ovary syndrome affecting ovulation induction outcome and fertility potential." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/4076.

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Thesis (DMed (Obstetrics and Gynaecology))--Stellenbosch University, 2008.<br>Chapter 1 presents a literature study on the diagnostic debate of PCOS. The literature study includes a discussion of the recent Rotterdam consensus statement regarding the diagnosis of PCOS. This is followed by a discussion on the essential work-up of the patient presenting with PCOS. Finally, chapter 1 presents a discussion on the complexity of the different variations in women presenting with PCOS. Chapter 2 is a literature review on ovulation induction methods in patients who present with PCOS. This literat
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41

Piltonen, T. (Terhi). "Age-related androgen secretion in healthy women and in women with polycystic ovary syndrome." Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274369.

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Abstract The number of ovarian follicles declines with age resulting in a significant decrease of fertility by the age of 40. However, the age when follicle loss starts to affect ovarian endocrine function is not well recognized. The purpose of the present study was to investigate age-related ovarian/adrenal androgen secretion, which is crucial for estrogen biosynthesis in healthy women and in women with polycystic ovarian syndrome (PCOS). Another aim of the study was to compare the usefulness of different serum markers in assessing ovarian aging and in diagnosing polycystic ovaries (PCOs) and
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Rehme, Marta Francis Benevides [UNESP]. "O hiperandrogenismo influencia no desenvolvimento de síndrome metabólica em pacientes com síndrome dos ovários policísticos?" Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/106373.

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Made available in DSpace on 2014-06-11T19:35:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-08-20Bitstream added on 2014-06-13T19:24:59Z : No. of bitstreams: 1 rehme_mfb_dr_botfm.pdf: 2280081 bytes, checksum: b44989e75865f4acff4695729feffce0 (MD5)<br>A síndrome dos ovários policísticos (SOP) afeta 5 a 8% das mulheres no menacme e é caracterizada pela anovulação crônica e hiperandrogenismo. A obesidade central e a resistência insulínica (RI) são freqüentes na SOP e desempenham um papel fundamental na etiopatogenia da síndrome metabólica (SM). O hiperandrogenismo tem sido questionad
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43

Mlekov, Andersson Andreas. "Polycystic ovary syndrome : A Drosophila Melanogaster Melanogaster disease model induced by DHT and/or high sugar diet." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-17318.

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Polycystic ovary syndrome is an endocrine disorder with symptoms of hyperandrogenism, insulin-resistance and anovulation in women which creates a disposition for other disorders, like Type 2 Diabetes. Drosophila Melanogaster flies have short generation, low cost-management and share several signaling pathways with humans and are therefore an excellent tools to study disease aetiology – yet no such model exists for PCOS. This thesis aimed to create such PCOS-like disease model through treatment of Drosophila Melanogaster adults and larvae with 5-α Dihydrotestosterone and/or high sugar diet. The
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Hamadi, Caroline. "Public health nutrition intervention to enhance healthy eating and lifestyle modification among Lebanese women with Polycystic Ovarian Syndrome." Thesis, University of Westminster, 2018. https://westminsterresearch.westminster.ac.uk/item/q947q/public-health-nutrition-intervention-to-enhance-healthy-eating-and-lifestyle-modification-among-lebanese-women-with-polycystic-ovarian-syndrome.

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Polycystic ovary syndrome (PCOS) is the most common endocrinopathy disorder in reproductive age women. The symptoms of this disorder are the androgen excess seen with anovulation/oligoovulation or morphologically ovarian cysts. The aim of the study was to assess the efficacy of public health nutrition intervention designed to enhance healthy eating and lifestyle modification among PCOS patients attended the obstetrics and gynecology clinic at the American University of Beirut Medical Centre (AUB-MC) in Beirut, Lebanon. A prospective hospital based public health nutrition intervention was propo
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Connolly, Fiona. "Reproductive and metabolic programming by exogenous steroids." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/17606.

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Polycystic ovary syndrome (PCOS) is a heterogeneous disorder encompassing reproductive and metabolic phenotypes. Genetic analysis, targeting candidate genes has to date proven unsuccessful in the search for a truly dominant genetic link. Another hypothesis to explain the etiology of PCOS is that of fetal programming in the context of developmental origins of health and disease. Extensive animal studies, validated by human data, support the fetal origins hypothesis of PCOS and highlight that PCOS may arise due to excess androgen exposure in fetal life. Previous reports from our laboratory found
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Rehme, Marta Francis Benevides. "O hiperandrogenismo influencia no desenvolvimento de síndrome metabólica em pacientes com síndrome dos ovários policísticos?" Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/106373.

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Orientador: Anaglória Pontes<br>Banca: Tamara Goldberg<br>Banca: Marcos Felipe Silva de Sá<br>Banca: José Alcione Macedo Almeida<br>Banca: Cleusa Cascaes Dias<br>Resumo: A síndrome dos ovários policísticos (SOP) afeta 5 a 8% das mulheres no menacme e é caracterizada pela anovulação crônica e hiperandrogenismo. A obesidade central e a resistência insulínica (RI) são freqüentes na SOP e desempenham um papel fundamental na etiopatogenia da síndrome metabólica (SM). O hiperandrogenismo tem sido questionado como um fator importante no desenvolvimento da SM em mulheres com SOP. Verificar se o hipera
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Nemade, Rashmi Vithal. "THE DISRUPTION OF THE BLOOD FOLLICLE BARRIER IN OVARIAN FOLLICULAR CYST DEVELOPMENT: REGULATION BY NITRIC OXIDE." University of Cincinnati / OhioLINK, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=ucin976039111.

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48

McCook, Judy G., Stacey Williams, Sheeba Anand, Beth Bailey, Nancy E. Reame, and Samuel Thatcher. "Risk Factors for Psychological Distress and Impaired Quality of Life In Women with Polycystic Ovary Syndrome: Implications for Providing Effective Nursing Care." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/7188.

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Objective: Polycystic ovary syndrome (PCOS) is a multidimensional endocrine disorder characterized by at least two of the following three features: hyperandrogenism, ovulatory dysfunction and/or polycystic ovaries. Prevalence is estimated at 5-10 % of women of reproductive age worldwide and may impact between five and ten million women in the U.S. alone. Rather than a distinct disease entity, PCOS is characterized as a clustering of clinical concerns which include hyperandrogenism, obesity, and menstrual abnormalities/infertility. Our intent was to examine how these three PCOS characteristics
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Mazier, Hannah. "Role of Mitochondrial Dynamics and Cell Death in a Dihydrotestosterone-induced Rat Model of Polycystic Ovarian Syndrome, and its Regulation by Gonadotropin." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35572.

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Polycystic ovarian syndrome (PCOS) is a multi-factorial infertility disorder whose etiology and pathogenesis is not completely understood. Although there is an association between dysregulation of mitochondrial fission and fusion to cell death (apoptotic and autophagic) and the pathogenesis of various diseases, this had not been reported in the context of granulosa cell death, follicular growth arrest and PCOS. Follicle-stimulating hormone (FSH), a granulosa cell survival factor, is used during gonadotropin therapy to assist in follicular maturation and ovulation in women with PCOS. Whether FS
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Turandar, Jasmine. "Polycystisk ovarialsyndrom: Se kvinnan bakom diagnosen : En kvalitativ metasyntes." Thesis, Högskolan Dalarna, Sexuell, reproduktiv och perinatal hälsa, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:du-35647.

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Bakgrund: Polycystisk ovarialsyndrom (PCOS) är den vanligaste hormonella rubbningen hos fertila kvinnor, ändå är den okänd för många. Det finns ett flertal symtom där dessa varierar från kvinna till kvinna. Okunskap kring PCOSförekommer både i vården liksom i samhället och diagnosen kan därför vara svåratt upptäcka. Att leva med symtomen från PCOS kan påverka negativt både kroppsligt och psykiskt. Hur kvinnor med diagnosen upplever PCOS behöverlyftas fram och förståelsen för dem behöver ökas både inom vården liksom förkvinnorna med PCOS. Med ökad förståelse kan ett bättre bemötande och vård ge
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