Academic literature on the topic 'PEG-PCL'

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Journal articles on the topic "PEG-PCL"

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Gou, MaLing, ChangYang Gong, Juan Zhang, et al. "Polymeric matrix for drug delivery: Honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel." Journal of Biomedical Materials Research Part A 9999A (2009): NA. http://dx.doi.org/10.1002/jbm.a.32546.

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Hwang, Min Ji, Ju Myung Suh, You Han Bae, Sung Wan Kim, and Byeongmoon Jeong. "Caprolactonic Poloxamer Analog: PEG-PCL-PEG." Biomacromolecules 6, no. 2 (2005): 885–90. http://dx.doi.org/10.1021/bm049347a.

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Alipour, Mahdieh, Javad Ashrafihelan, Roya Salehi, et al. "In vivo evaluation of biocompatibility and immune modulation potential of poly(caprolactone)–poly(ethylene glycol)–poly(caprolactone)-gelatin hydrogels enriched with nano-hydroxyapatite in the model of mouse." Journal of Biomaterials Applications 35, no. 10 (2021): 1253–63. http://dx.doi.org/10.1177/0885328221998525.

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Biocompatible, biodegradable, and injectable hydrogels are a novel and promising approach for bone regeneration. In this study, poly(caprolactone)–poly(ethylene glycol)–poly(caprolactone) (PCL-PEG-PCL), PCL-PEG-PCL-gelatin (Gel), PCL-PEG-PCL-Gel/nano-hydroxyapatite (nHA) injectable hydrogels were synthesized and evaluated in a mouse model of subcutaneous transplantation after 14 days. PCL-PEG-PCL-Gel and PCL-PEG-PCL-Gel/nHA hydrogels were fabricated with in situ precipitation method. Structure, intermolecular interaction, and the reaction between the PCL-PEG-PCL, Gel, and nHA were evaluated us
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Manjili, Hamidreza Kheiri, Ali Sharafi, Hossein Danafar, Mirjamal Hosseini, Ali Ramazani, and Mohammad Hossein Ghasemi. "Poly(caprolactone)–poly(ethylene glycol)–poly(caprolactone) (PCL–PEG–PCL) nanoparticles: a valuable and efficient system for in vitro and in vivo delivery of curcumin." RSC Advances 6, no. 17 (2016): 14403–15. http://dx.doi.org/10.1039/c5ra24942b.

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Wang, Jian Hua, Shuen Liang, Yan Yan Wang, Chun Rong Tian, and Xiu Li Zhao. "Mechanical and Dynamic Mechanical Properties of Degradable Polyurethane Foams with PEG/PCL Mixed Soft Segments." Advanced Materials Research 183-185 (January 2011): 1611–15. http://dx.doi.org/10.4028/www.scientific.net/amr.183-185.1611.

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Polyurethane (PU) with mixed poly(ethylene glycol) / poly(ε-caprolactone) (PEG/PCL) soft segments is a representatively kind of degradable polyurethane material. Polyurethane foams (PUF) with mixed PEG/PCL soft segments were synthesized by using one pot method, and their mechanical and dynamic mechanical properties were investigated. Influences of PEG/PCL weight ratio and molecular weight of soft segments on PUF's mechanical and dynamic mechanical properties were studied. The results showed that: with increasing content of PCL, PUF's tensile strength, elongation at break, stress at certain ten
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Du, Xu, Qin Wang, Chuan Dong Wang, and Yang Liu. "Synthesis and Self-Assembly Study of Biodegradable Amphiphilic Triblock Copolymers with PEG Block." Advanced Materials Research 998-999 (July 2014): 95–98. http://dx.doi.org/10.4028/www.scientific.net/amr.998-999.95.

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Three biodegradable amphiphilic triblock copolymers: polylactide-poly (ethylene glycol)-polylactide (PLA-PEG-PLA), poly (ε-caprolactone)-poly (ethylene glycol)-poly (ε-caprolactone) (PCL-PEG-PCL) and poly (lactide-glycolide)-poly (ethylene glycol)-poly (lactide-glycolide) (PLGA-PEG-PLGA) were synthesized. Their chemical structures were characterized. In aqueous solution, their self-assembly and degradation were studied by dynamic light scattering (DLS) and transmission electron microscopy (TEM). Spherical micelles were formed in aqueous solution via self-assembly of the amphiphilic triblock co
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Zhou, Yanyan, Lei Li, Wei Chen та ін. "A twin-tailed tadpole-shaped amphiphilic copolymer of poly(ethylene glycol) and cyclic poly(ε-caprolactone): synthesis, self-assembly and biomedical applications". Polymer Chemistry 9, № 33 (2018): 4343–53. http://dx.doi.org/10.1039/c8py00022k.

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Lee, Hyun Jung, and Byeongmoon Jeong. "ROS‐Sensitive Degradable PEG–PCL–PEG Micellar Thermogel." Small 16, no. 12 (2020): 1903045. http://dx.doi.org/10.1002/smll.201903045.

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Yu, Lin, Hongtao Hu, Lin Chen, et al. "Comparative studies of thermogels in preventing post-operative adhesions and corresponding mechanisms." Biomater. Sci. 2, no. 8 (2014): 1100–1109. http://dx.doi.org/10.1039/c4bm00029c.

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Lee, Jin Woo, and Kuk Ro Yoon. "Fabrication and characterization of block copolymer (PCL/PCL-PEG) nanofibers binding with collagen by electrospun." Analytical Science and Technology 27, no. 5 (2014): 228–33. http://dx.doi.org/10.5806/ast.2014.27.5.228.

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Dissertations / Theses on the topic "PEG-PCL"

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Vasconcelos, Juliana de Almeida Pachioni. "Desenvolvimento de vesículas poliméricas de poli(etileno glicol)-b-poli(ε-caprolactona) (PEG-PCL) para veiculação de L-asparaginase." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/9/9135/tde-26072018-154155/.

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A L-Asparaginase (ASNase) é um importante agente quimioterapêutico utilizado para o tratamento da leucemia linfoblástica aguda (ALL) há mais de 40 anos. No entanto, devido à origem biológica da ASNase, enzima produzida por Escherichia coli, problemas como a imunogenicidade e baixa meia vida-plasmática devem ser considerados. Com o objetivo de minimizar essas desvantagens, várias ASNases homólogas bem como formulações de ASNase de E. coli foram investigadas. Nenhuma das formulações desenvolvidas, entretanto, foi capaz de resolver definitivamente esses problemas associados à sua origem. Nesse se
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Endres, Thomas [Verfasser], and Thomas [Akademischer Betreuer] Kissel. "Biodegradable amphiphilic PEG-PCL-PEI triblock copolymers designed for the self-assembly of multifunctional gene carriers / Thomas Endres. Betreuer: Thomas Kissel." Marburg : Philipps-Universität Marburg, 2013. http://d-nb.info/103231396X/34.

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RODRIGUES, KIRIAKI M. S. "Influência de polietilenoglicol (PEG) na liberação modificada de teofilina em comprimidos de poli-3-midroxibutirato (PHB) e poli-e-caprolactona (PCL)." reponame:Repositório Institucional do IPEN, 2008. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10155.

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Made available in DSpace on 2014-10-09T12:35:24Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:05:36Z (GMT). No. of bitstreams: 0<br>Dissertação (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Zhu, Xiaobo. "DESIGN AND SYNTHESIS OF BLOCK COPOLYMERS THAT SELF ASSEMBLE INTO MICELLES WITH CONTROLLED ACID AND LIPASE CATALYZED DEGRADATION." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/250374.

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Chemistry<br>Ph.D.<br>Poly (&#949;-caprolactone) block poly (ethylene glycol) (PCL-b-PEG) is typical amphiphilic block copolymer that self assembles into micelles in water where the hydrolytically stable hydrophilic PEG segment forms the exterior corona and the core contains the hydrophobic degradable PCL block. Micelles from PCL-b-PEG block copolymers are among the top candidates for application as transport and delivery systems. The efficiency for micellar transported therapeutics to reach the desired site is currently limited by processes that prematurely degrade the micelle and this issue
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Montenegro-Galindo, Gladys Rocio. "Synthesis and Protein Adsorption Studies of Pegylated-Polyester Nanoparticles with Different Peg Architectures." University of Akron / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=akron1384629996.

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Satyal, Uttam. "Efficient Drug and Nucleic Acid Delivery Systems based on Synthetic Amphiphiles with Tuned Oil/Water Interfaces." Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/531985.

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Pharmaceutical Sciences<br>Ph.D.<br>Today, drugs are an integral part of healthy human life, with new drug entities being introduced every year in clinic. The advancement of drug development brings complexity and variation, in terms of both physical and chemical properties. Some of these physicochemical characteristics are many times suboptimal, eventually requiring robust delivery systems that can precisely deliver the drugs to the desired tissues. Although many materials have been studied for the generation of drug delivery systems, there is always a need for biomaterials with better propert
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Gontard, Gwenaëlle. "Synthèse de nanoconjugués PEG-PLA pour des applications biomédicales : libération contrôlée et Imagerie." Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30279.

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Ce travail de thèse s’inscrit dans le cadre d’une collaboration entre Sanofi à Vitry-sur-Seine et le Laboratoire Hétérochimie Fondamentale et Appliquée (LHFA) à Toulouse, et a pour but de développer de nouveaux nanovecteurs à base de conjugués polymériques biodégradables et biocompatibles capables d’encapsuler, de transporter et de libérer des agents thérapeutiques. Les travaux précédemment réalisés au laboratoire, ont montré que la libération de principes actifs hydrophobes, tels que le Cabazitaxel de la famille des taxanes, pouvait être contrôlée grâce à l’architecture de conjugués de nature
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Castano, Gil Yenni Marcela. "Green Polymer Chemistry: The Role of Candida Antarctica Lipase B in Polymer Functionalization." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1398034236.

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Yen, Chi. "Synthesis and Surface Modification of Nanoporous Poly(ε-caprolactone) Membrane for Biomedical Applications". The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1268074499.

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Fidalgo, Andreia Filipa Teixeira. "Otimização da síntese de copolímeros PCL/PEG." Master's thesis, 2017. http://hdl.handle.net/10316/82931.

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Dissertação de Mestrado Integrado em Engenharia Química apresentada à Faculdade de Ciências e Tecnologia<br>Na sociedade atual são múltiplos os problemas associados à visão, como a cataratas e o glaucoma. Ao longo dos anos, tem sido desenvolvida investigação em prol da qualidade de vida do Homem, nomeadamente no sentido de melhorar o tratamento e acompanhamento de casos clínicos. Porém, o maior desafio no tratamento das doenças oculares persiste. A capacidade de manutenção do nível terapêutico do fármaco no local de ação, durante o período de tempo necessário, continua a ser uma das dificuldad
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Book chapters on the topic "PEG-PCL"

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Jiang, J. L., N. V. Cuong, S. C. Jwo, and M. F. Hsieh. "Nano-Sized Drug Carrier for Cancer Therapy: Dose-Toxicity Relationship of PEG-PCL-PEG Polymeric Micelle on ICR Mice." In XII Mediterranean Conference on Medical and Biological Engineering and Computing 2010. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13039-7_203.

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Parwez, Khalid, Arun A. Bhagwath, Asif Zawed, Bhagwan Rekadwad, and Suman V. Budihal. "Carbon Nanotubes Integrated Hydroxyapatite Nano-Composite for Orthopaedic and Tissue Engineering Applications." In Sol Gel and other Fabrication Methods of Advanced Carbon Materials [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97428.

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The reassessment of the literature stipulates that an increasing amount of research in exploring the Hydroxyapatite Carbon Nanotubes (HA-CNT) system for orthopedic application. Chemical precipitation, CNT functionalization, and spray drying are the routinely used methods for CNT dispersal in HA matrix for the application such as bone tissue engineering, nanostructured scaffolds, dental regeneration, myocardial regeneration, and skin regeneration. Although mechanical strength and biocompatibility is a substantial concern for the fabrication of structures. Developing composite and bioceramic scaffolding with different natural and synthetic biomaterials are the futuristic approach in the biomedical engineering field. The problems such as biocompatibility, biodegradability, and mechanical resistance can be solved by combining natural, and artificial biomaterials. The natural biomaterials, such as collagen, cellulose, chitosan, have a close resemblance to the natural extracellular matrix (ECM). These materials are biocompatible, biodegradable. The artificial biomaterials, such as Poly Vinyl Pyrrolidone (PVP), Poly Capro Lactone (PCL), Poly Ethylene Glycol (PEG), and Poly Lactic Acid (PLA) are also the material of choice for the fabrication of the composite materials. Additional effort is necessary to fabricate biocompatible composite scaffolding for tissue engineering. Moreover, vascularization, differentiation, cellular proliferation, and cells to scaffold interaction are the foremost challenges in the area of tissue engineering that remains to overcome.
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Conference papers on the topic "PEG-PCL"

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Zhu, Yazhi, Mingqiang Zhong, and Feng Chen. "Preparation and properties of biocompatible PCL-PEG-PCL(PCEC)." In MATERIALS CHARACTERIZATION USING X-RAYS AND RELATED TECHNIQUES. Author(s), 2019. http://dx.doi.org/10.1063/1.5088323.

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Cheng, Yih-Lin, Freeman Chen, Yu-Wei Hsu, and Ying-Chieh Huang. "Biodegradable photocurable PCL/PEG-diacrylate for 3D printing." In 2016 IEEE International Conference on Industrial Technology (ICIT). IEEE, 2016. http://dx.doi.org/10.1109/icit.2016.7474916.

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Isabel Felisberti, Maria, and Lucas Polo Da Fonseca. "Chemically Crosslinked Polyurethane Hydrogels Based on PEG and PCL." In XXIII Congresso de Iniciação Científica da Unicamp. Galoá, 2015. http://dx.doi.org/10.19146/pibic-2015-37554.

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Pungkham, H., N. Swatdipakdi, M. Theerasilp, et al. "PEG-b-PCL and PEG-b-PLA polymeric micelles as nanocarrieres for lamellarin N delivery." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090882.

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Cheng, Yih-Lin, Yu-Kai Yang, and Jia-Yan Hou. "Preparation and Characterization of Photo-Curable PCL/PEG-Diacrylate for Additive Manufacturing Tissue Engineering Scaffold Application." In 1st International Conference on Progress in Additive Manufacturing. Research Publishing Services, 2014. http://dx.doi.org/10.3850/978-981-09-0446-3_029.

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Castro, Nathan J., Christopher O’Brien, and Lijie Grace Zhang. "Development of Biomimetic and Bioactive 3D Nanocomposite Scaffolds for Osteochondral Regeneration." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-66107.

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Osteochondral tissue is composed of ordered and random biological nanostructures and can, in principal, be classified as a nanocomposite material. Thus, the objective of this research is to develop a novel biomimetic biphasic nanocomposite scaffold via a series of 3D fabricating techniques for osteochondral tissue regeneration. For this purpose, a highly porous Poly(caprolactone) (PCL) bone layer with bone morphogenetic protein-2 (BMP-2)-encapsulated Poly(dioxanone) (PDO) nanospheres and nanocrystalline hydroxyapatite was photocrosslinked to a Poly(ethylene glycol)-diacrylate (PEG-DA) cartilag
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