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Relevant bibliographies by topics / Periodontal cells

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Academic literature on the topic 'Periodontal cells'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

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Journal articles on the topic "Periodontal cells"

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Nokhbehsaim, Marjan, Anna Damanaki, Andressa Vilas Boas Nogueira, et al. "Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo." Mediators of Inflammation 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/4916971.

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Ghrelin plays a major role in obesity-related diseases which have been shown to be associated with periodontitis. This study sought to analyze the expression of the functional receptor for ghrelin (GHS-R1a) in periodontal cells and tissues under microbial conditions in vitro and in vivo. The GHS-R1a expression in human periodontal cells challenged with the periodontopathogen Fusobacterium nucleatum, in gingival biopsies from periodontally healthy and diseased individuals, and from rats with and without ligature-induced periodontitis was analyzed by real-time PCR, immunocytochemistry, and immun

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Marjanović, D., Z. Anðelković, N. Videnović, et al. "MAST CELLS IN PERIODONT PERIODONTAL DISEASE DISEASE." Praxis medica 35, no. 2 (2007): 99–102. http://dx.doi.org/10.70949/pramed200702210m.

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&lt;p&gt;Periodontal disease is a chronic inflammatory disease that is largely attributable to infections with gram-negative bacteria and is characterised by both gingival inflammation and alveolar bone resorption. Beside macrophages, the second most common cells of the gingival inflammatory infiltrat are mast cells. Mast cells are heterogenous cell population which live from six months to one year. These cells are activated by differnt immunologic and non-immunologic signals. Activated mast cells can secrete a range of substances that regulate angiogenesis, tissue remodeling and wound

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Mancini, Leonardo, Adriano Fratini, and Enrico Marchetti. "Periodontal Regeneration." Encyclopedia 1, no. 1 (2021): 87–98. http://dx.doi.org/10.3390/encyclopedia1010011.

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Periodontal regeneration is a technique that aims to regenerate the damaged tissue around periodontally compromised teeth. The regenerative process aims to use scaffolds, cells, and growth factors to enhance biological activity.

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Fabila-Plata, Miriam Susana, and Rosa Diana Hernández Palacios. "Tratamiento de la enfermedad periodontal con células troncales de origen pulpar, en un adulto mayor. Caso clínico." Casos y Revisiones de Salud 3, no. 1 (2021): 32–39. http://dx.doi.org/10.22201/fesz.26831422e.2021.3.1.4.

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Introducción. La enfermedad periodontal (EP) es un padecimiento de tipo inflamatorio crónico y con frecuencia causa pérdida dental en los adultos mayores. Su tratamiento se orienta a la regeneración de los tejidos periodontales a través de la eliminación de los agentes infecciosos presentes en el periodonto y en la sustitución del hueso alveolar perdido. Caso clínico. Paciente femenina de 61 años de edad que acudió a consulta estomatológica por presentar movilidad dental. En la valoración bucal se observó enfermedad periodontal. Se realizaron las tres fases de la terapia periodontal con aplica

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Aditya, Vangara, and Kharidhi Laxman Vandana. "Management of endo-perio lesion with autologous stem cell therapy." Saudi Journal of Oral Sciences 11, no. 1 (2024): 54–59. http://dx.doi.org/10.4103/sjoralsci.sjoralsci_79_23.

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The objective of periodontal therapy is the regeneration of tooth-supporting tissues. Various treatment modalities, such as the use of bone grafting materials, guided tissue regeneration, and delivery of enamel matrix derivatives or growth factors, are applied with large variability in regenerative outcomes. However, a case report was done by utilization of autologous dental pulp stem cells and periodontal ligament stem cell niches in the treatment of bone loss associated with endodontically and periodontally involved teeth. An autologous periodontal ligament stem cells niche adherent to the r

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Nighojkar, Urvashi Rajeev, Dr Priya A. Lele, and Mudita Agrawal. "Scope of Stem Cells in Periodontal Regeneration." International Journal of Scientific Research 2, no. 5 (2012): 428–31. http://dx.doi.org/10.15373/22778179/may2013/145.

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Karunanithi Arulvizhi M, Arunagiri. "Stem Cells in Periodontal Regenerations - A Review." International Journal of Science and Research (IJSR) 13, no. 2 (2024): 589–94. http://dx.doi.org/10.21275/sr24206105401.

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Gonçalves, Gabriela Sumie Yaguinuma, Tayna Natsumi Takakura, Anderson Catelan, Rosalinda Tanuri Zaninotto Venturim, Carolina dos Santos Santinoni, and Christine Men Martins. "Tratar ou extrair? Tratamento de lesão endoperiodontal, um relato de caso clínico." ARCHIVES OF HEALTH INVESTIGATION 9, no. 6 (2020): 535–40. http://dx.doi.org/10.21270/archi.v9i6.4814.

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Introdução: Lesões endoperiodontais são lesões originadas de produtos inflamatórios encontrados tanto em periodonto quanto em polpa. Tais lesões podem se originar devido a uma infecção pulpar ou periodontal. Visando o prognóstico favorável, é imprescindível o conhecimento da etiologia, realização do correto diagnóstico e elaboração do plano de tratamento que envolve o tratamento endodôntico precedido do tratamento periodontal. Objetivo: O propósito do presente trabalho foi de relatar um caso clínico de lesão endoperiodontal e o tratamento realizado. Relato de caso clínico: Paciente gênero femi

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Song, In Seok, Yoon Sic Han, Joo-Hee Lee, Soyoun Um, Hui Young Kim, and Byoung Moo Seo. "Periodontal Ligament Stem Cells for Periodontal Regeneration." Current Oral Health Reports 2, no. 4 (2015): 236–44. http://dx.doi.org/10.1007/s40496-015-0060-0.

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Hosokawa, Yoshitaka, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki та Takashi Matsuo. "IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells". Cellular Physiology and Biochemistry 38, № 1 (2016): 153–59. http://dx.doi.org/10.1159/000438617.

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Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions. The aim of this study was to examine the effects of IL-4 on CCL11, which is a Th2-type chemokine, and CCL20, which is related with Th17 cells migration, productions from human periodontal ligament cells (HPDLCs). Methods: CCL20 and CCL11 productions from HPDLCs were monitored by ELISA. Western blot analysis was performed to detect phosphorylations of signal transduction molecule

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Dissertations / Theses on the topic "Periodontal cells"

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Worapamorn, Wilairat. "Cell-surface proteoglycan expression by periodontal cells /." St. Lucia, Qld, 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16097.pdf.

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Gay, Isabel C. "Isolation and characterization of human periodontal ligament stem cells." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. http://www.mhsl.uab.edu/dt/2007m/gay.pdf.

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Stoianovici, Charles. "Directing Mesenchymal Stem Cells for Periodontal Regeneration." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5335.

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Background: Directing autogenous Mesenchymal Stem Cell (MSC) to defect sites has a great promise in bone regeneration. We designed a MSC specific, bone affinity peptide (E7HA7) by conjugating E7 with a polyglutamate hydroxyapatite (HA) binding motif. We sought to characterize the in-vivo releasing pattern and bioactivity of E7HA7. Methods: HA discs were coated with fluorescent labeled peptides E7HA7, E7HA2 or E7 were subcutaneously implanted in Sprague Dawley rats. In an ectopic bone formation model was used to test the in-vivo bioactivity of E7HA7 conjugated to DBM. Results: E7HA7 showed slow

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Winning, Lewis. "The osteogenic potential of periodontal ligament stem cells." Thesis, Queen's University Belfast, 2018. https://pure.qub.ac.uk/portal/en/theses/the-osteogenic-potential-of-periodontal-ligament-stem-cells(e5fdef0e-d55b-42b6-acb5-75a617b43edd).html.

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Campbell, Lauren Dee. "The role of CD4+ T cells in periodontal disease." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8241/.

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Introduction: Periodontal disease (PD) is the most common bone destructive chronic inflammatory disease in humans. Severe PD affects 8-15% of the population and impacts on the ability to chew and appearance, reduces quality of life, and is responsible for a substantial proportion of dental care costs. A dysbiotic oral biofilm is necessary but insufficient for development of PD. Rather, a dysregulated immune response to the disease-associated biofilm results in destruction of tooth supporting structures and eventual tooth loss. Despite the apparent involvement of the immune system in PD, clinic

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Åsman, Björn. "Juvenile periodontitis generation of free oxygen radicals and elastase by peripheral PMN cells /." Stockholm : Kongl. Carolinska Medico Chirurgiska Institutet, 1988. http://catalog.hathitrust.org/api/volumes/oclc/18171198.html.

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Engman, Sara. "Expression and Regulation of the Cell Surface Proteins CD47 and SIRPα in Resident Periodontal Cells". Thesis, Umeå universitet, Institutionen för odontologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-129258.

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Periodontal disease is an inflammatory disorder affecting the supporting tissues of the tooth. The inflammation triggers a destruction of the connective- and bone tissue surrounding the tooth, a process that is not fully elucidated. It is known that periodontitis shares features with other inflammatory disease like Crohn's disease and rheumatoid arthritis. The cell surface proteins signal regulatory protein alpha (SIRPα) and cluster of differentiation 47 (CD47) are important for the progression of the inflammation in rheumatoid arthritis and Crohn's disease. It has also been shown that lack of

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Bou, Chebel Najib. "Periodontal bacterial-DNA initiated immuno-inflammatory responses in human osteoblastic cells." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/97.

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Periodontitis is a chronic inflammatory disease initiated by gram negative anaerobic bacteria. These bacteria possess pathogen-associated molecular patterns (PAMPs) that interact with various receptors including Toll like receptors (TLRs). Bacterial DNA (bDNA) is one of the PAMPs mainly recognized by TLR9. Interaction of bDNA and its receptors leads to activation of inflammatory signaling pathways potentially resulting in periodontal bone destruction. The aim of this study was to determine the production of IL- 6 and IL-8 in response to periodontal bDNA from human osteoblastic cells (MG-

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Moore, Edward Andrew. "Cell attachment and spreading on physical barriers used in periodontal guided tissue regeneration /." Oklahoma City : [s.n.], 2002. http://library.ouhsc.edu/epub/theses/Moore-William-A.pdf.

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Wescott, David Clark, and n/a. "Osteogenic gene expression by human periodontal ligament cells under cyclic mechanical tension." University of Otago. School of Dentistry, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081202.131453.

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Background and objectives: The most widely accepted tooth movement model is defined by the pressure-tension hypothesis. An orthodontic force applied to a tooth generates areas of compression and tension in the periodontal ligament (PDL), which are transmitted to the alveolar bone. Areas of tissue exposed to tensile strain undergo bone deposition, whereas areas of tissue exposed to compressive strain undergo bone resorption. We propose that human PDL cells in monolayer culture exposed to tensile mechanical strain would express multiple genes involved in osteogenesis. Materials and Methods: Hu

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Books on the topic "Periodontal cells"

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sman, Bjo rn A. Juvenile periodontitis: Generation of free oxygen radicals and elastase by peripheral PMN cells. Kongl. Carolinska Medico Chirurgiska Institutet, 1988.

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2

Lin, Deborah G. Storage conditions of avulsed teeth affect the phenotype of cultured human periodontal ligament cells. Faculty of Dentistry, University of Toronto, 1999.

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Fardal, Øystein. Initial attachment of fibroblast-like cells to periodontally diseased root surfaces in vitro. Faculty of Dentistry, University of Toronto, 1985.

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Soory, Mena. Concepts of Periodontal Regeneration and Regenerative Medicine: Mechanisms That Modulate Cells and Matrices. Nova Science Publishers, Incorporated, 2015.

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Devlin, Hugh, and Rebecca Craven. Bone. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759782.003.0004.

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Bone in relation to dentistry is the topic of this chapter. This chapter describes the mineral, cells, vascular and matrix components of bone. Throughout the chapter, the clinical relevance of these features and how they interact in health and disease are emphasized. The later parts of the chapter describe bone healing, bone grafts, healing of the extraction socket, orthodontic tooth movement, periodontal bone loss in chronic periodontitis, and the effect of bisphosphonates. A final section summarizes age changes in bone and bone cells.

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Devlin, Hugh, and Rebecca Craven. Diabetes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759782.003.0007.

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Diabetes in relation to dentistry is the topic of this chapter. The incidence of diabetes is increasingly rapidly, hand-in-hand with the increase in obesity. Obesity predisposes patients to an increased insulin resistance, i.e. reduces their ability to increase the glucose transport into adipocytes, muscle, and liver cells. The pancreas responds by producing more insulin but when it can no longer produce enough to overcome the insulin resistance, the blood glucose rises. Diabetes is characterized by raised blood glucose. We describe the devastating long-term effects of diabetes, in particular

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Larjava, Hannu. Oral Wound Healing: Cell Biology and Clinical Management. Wiley & Sons, Incorporated, John, 2012.

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Larjava, Hannu. Oral Wound Healing: Cell Biology and Clinical Management. Wiley & Sons, Limited, John, 2013.

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Larjava, Hannu. Oral Wound Healing: Cell Biology and Clinical Management. Wiley & Sons, Incorporated, John, 2012.

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Larjava, Hannu. Oral Wound Healing: Cell Biology and Clinical Management. Wiley & Sons, Incorporated, John, 2012.

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Book chapters on the topic "Periodontal cells"

1

Takeuchi, Hiroki, and Atsuo Amano. "Invasion of Gingival Epithelial Cells by Porphyromonas gingivalis." In Periodontal Pathogens. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0939-2_21.

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Matsushita, Kenji. "Analysis of Interaction Between Porphyromonas gingivalis and Endothelial Cells In Vitro." In Periodontal Pathogens. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0939-2_22.

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Hasebe, Akira, Ayumi Saeki, and Ken-ichiro Shibata. "Lipoprotein Extraction from Microbial Membrane and Lipoprotein/Lipopeptide Transfection into Mammalian Cells." In Periodontal Pathogens. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0939-2_19.

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Imai, Kenichi. "Analysis of the Interaction Between HIV and Periodontopathic Bacteria That Reactivates HIV Replication in Latently Infected Cells." In Periodontal Pathogens. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0939-2_20.

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Pagni, Giorgio. "Stem Cells for Periodontal Regeneration." In Dental Stem Cells: Regenerative Potential. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33299-4_9.

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Kao, Richard T., and Mark C. Fagan. "Regeneration of Intrabony Defects Utilizing Stem Cells Allograft." In Advances in Periodontal Surgery. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-12310-9_7.

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Tobita, Morikuni, and Hiroshi Mizuno. "Adipose-Derived Stem Cells for Periodontal Tissue Regeneration." In Adipose-Derived Stem Cells. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-61737-960-4_34.

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Wang, Songlin, Gang Ding, Fulan Wei, and Yi Liu. "Bioengineering of Roots and Periodontal Tissues." In Stem Cells in Craniofacial Development and Regeneration. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118498026.ch27.

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Calenic, Bogdan, and Ken Yaegaki. "DNA Damage Caused by Oral Malodorous Compounds in Periodontal Cells In Vitro: Novel Carcinogenic Pathway." In Studies on Periodontal Disease. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9557-4_5.

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Maeda, Hidefumi, Shinsuke Fujii, Satoshi Monnouchi, Naohisa Wada, and Akifumi Akamine. "Differentiation of Periodontal Ligament Stem/Progenitor Cells: Roles of TGF-β1." In Stem Cells and Cancer Stem Cells, Volume 4. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2828-8_5.

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Conference papers on the topic "Periodontal cells"

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Abraham, Sarin, Pallavi Gupta, Kavitha Govarthanan, Suresh Rao, and Tuhin Subhra Santra. "3D Printed Cell and Fiber Guiding Scaffold Mimicking Periodontal Architecture." In 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2024. http://dx.doi.org/10.1109/nems60219.2024.10639845.

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Gao, Zhen, and Xiaoting Luo. "Biological Effect of Titanium's Surface Roughness on Periodontal Ligament Cells." In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5162449.

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Si-Eun Kim, Soo-Hyuk Uhm, Doo-Hoon Song, et al. "Enhanced funtion of human periodontal ligament cells cultured on nanoporous titanium surfaces." In 2012 IEEE 39th International Conference on Plasma Sciences (ICOPS). IEEE, 2012. http://dx.doi.org/10.1109/plasma.2012.6383859.

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Lee, Jaeyul, Jaeseok Park, Muhammad Faizan Shirazi, et al. "Imaging of periodontal tissue using swept-source optical coherence tomography for measurement of gingival sulcus depth (Conference Presentation)." In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII, edited by Daniel L. Farkas, James F. Leary, and Attila Tarnok. SPIE, 2020. http://dx.doi.org/10.1117/12.2547280.

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Yining Wang, Haibin Xia, Yan Zhao, and Tao Jiang. "Three-Dimensional Culture of Human Periodontal Ligament Cells on Highly Porous Polyglycolic Acid Scaffolds in vitro." In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1615573.

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Mohamed Zaid, Hagar, Khaled Abdel-ghaffar, Tarek Hessin El-bialy, Mamdouh Farid, and Fatma Hamed M. El-demerdash. "Evaluation Of Regenerative Potential Of Pulp -derived Stem Cells And Gingival-derived Stem Cells In The Regeneration Of Periodontal Defects (experimental Study)." In Qatar Foundation Annual Research Conference Proceedings. Hamad bin Khalifa University Press (HBKU Press), 2014. http://dx.doi.org/10.5339/qfarc.2014.hbpp0741.

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Hessin El-bialy, Tarek, Jacqueline Crossman, Ali Saleem, Khaled Abdel-ghaffar, Mamdouh Farid, and Elham Fawzi. "Effect Of Using Gingival Stem Cells And Therapeutic Ultrasound On Periodontal Ligament During Orthodontic Treatment In Beagle Dogs." In Qatar Foundation Annual Research Conference Proceedings. Hamad bin Khalifa University Press (HBKU Press), 2014. http://dx.doi.org/10.5339/qfarc.2014.hbpp0060.

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Valverde, Mariana Bonilla, and Rodrigo Mora Rodriguez. "miRNA networks regulating gene expression in response to tension or compression forces in the cells of the periodontal ligament." In 2022 IEEE 4th International Conference on BioInspired Processing (BIP). IEEE, 2022. http://dx.doi.org/10.1109/bip56202.2022.10032478.

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Santos, Karoline dos, Karina Ruiz, and Catharina Sacramento. "Evaluation of 5-Azacytidine as an inducer of osteoblastic / cementoblastic differentiation of progenitor cells from the periodontal ligament of humans." In Congresso de Iniciação Científica UNICAMP. Universidade Estadual de Campinas, 2019. http://dx.doi.org/10.20396/revpibic2720192363.

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Andriani, Ika, Atiek Driana Rahmawati, Maulida Nurhasanah, and M. Ihza Humanindito. "The Effects of Antimicrobial Peptide Gel on Angiogenesis and Fibroblast Cells in Periodontal Tissue Regeneration in a Periodontitis Rats Model Exposed by Nicotine." In 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020). Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210115.036.

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Reports on the topic "Periodontal cells"

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Pavasant, Prasit, and Tussanee Yongchaitrakul. Influence of mechanical stress on the expression of osteopontin in human periodontal ligament cells. Chulalongkorn University, 2008. https://doi.org/10.58837/chula.res.2008.14.

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Background: Mechanical stress such as orthodontic forces can produce mechanical damage and inflammatory reaction in periodontium. Osteopontin (OPN) is a multifunctional cytokine that found to be correlated with periodontal disease progression. As periodontal ligaments (PDL) can be affected by stress and PDL cells are involved in periodontal destruction and remodeling, we aimed to investigate the influence of mechanical stress on the expression and regulation of OPN in human PDL (HPDL) cells. Methods: The mechanical stress was generated by continuous compressive force and the expression of OPN

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Osathanon, Thanaphum. Gene expression profile of continuous and intermittent compressive stress treated human periodontal ligament cells. Faculty of Dentistry Chulalongkorn University, 2019. https://doi.org/10.58837/chula.res.2019.7.

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Mechanical force regulates periodontal ligament cell (PDL) behavior. However, different force types lead to distinct PDL responses. Here, we report that pretreatment with an intermittent compressive force (ICF), but not a continuous compressive force (CCF), promoted human PDL (hPDL) osteogenic differentiation as determined by osteogenic marker gene expression and mineral deposition in vitro. ICF-induced osterix (OSX) expression was inhibited by cycloheximide and monensin. Although CCF and ICF significantly increased extracellular adenosine triphosphate (ATP) levels, pretreatment with exogenous

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Sumrejkanchanakij, Piyamas, Prasit Pavasant, and Tusanee Yongchaitrakul. The influence of collagen I on Insulin-like growth factor-I induced Osteopontin expression in human periodontal ligament fibroblasts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.14.

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Extracellular matrix and growth factors are the crucial factors that regulate healing and regenerating process in human periodontal ligament (HPDL) cells. The purpose of this study was to examine the effects of type I collagen and insulin-like growth factor-I (IGF-I) on osteopontin (OPN) expression. The data showed that OPN expression was significantly decreased when cells were cultured on collagen-coated plates. Addition of IGF-I obviously induced OPN expression only in a collagen-coated condition, suggesting an attenuation effect of IGF-I on OPN expression inhibited by type I collagen. Cells

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Chansiripornchai, Piyarat, and Thanaphum Osathanon. In vitro differentiation of mesenchymal stem cells from dental and oral tissues into Islet-like cell cluster. Chulalongkorn University, 2013. https://doi.org/10.58837/chula.res.2013.93.

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Diabetes mellitus is a complicated metabolic disorder resulting in hyperglycemia and long-term complications e.g. diabetic encephalopathy and neuropathy. Treatments of diabetes and its complications have faced many obstacles. Trend of stem cells (SCs)-based therapy has been proposed as a novel approach. Though, the study using dental SCs in this regard is yet lacking. In this study, human dental pulp SCs (hDPSCs) and human periodontal ligament SCs (hPDLSCs) were employed. The results illustrated the capability of differentiation toward islet-like cells (ILCs) cluster / insulin-producing cells

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Zhang, Yuhao, Wenheng Zhao, Liyang Jia, Nan Xu, Yan Xiao, and Qiyan Li. The application of stem cells in tissue engineering for periodontal defects in randomized controlled trial: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0036.

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Yongchaitrakul, Tassanee, and Prasit Pavasant. Effect of LPS of Actinobacillus actinomycetemcomitans lipopolysaccharide on matrix metalloproteinase-2 and changes of RANKL and OPG in HPDL cell. Chulalongkorn University, 2004. https://doi.org/10.58837/chula.res.2004.13.

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Background: The LPS of A.actinomycetemcomitans is one of the major pathogenic factors in periodontal disease. It induces secretion of pro-inflammatory cytokines and involves in alveolar bone destruction. We hypothesized that the LPS of A.actinomycetemcomitans could affect the activation of MMP-2 and the expression of RANKL and OPG in HPDL cells leading to the destruction of periodontium. Methods: HPDL cells were cultured in serum-free medium with or without the LPS of A.actinomycetemcomitans for 36 hours. The activation of MMP-2 was analyzed by zymography. Changes of the expression of RANKL an

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Hu, Jing, Zeyue Ouyang, Yue Guo, and YunZhi Feng. Clinical application and efficacy of mesenchymal stem cells in the regeneration of periodontal defects: a systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.5.0097.

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Torrungruang, Kitti, and Suchada Chutimawarapun. Antimicrobial activity against periodontopathic bacteria, cell toxicity against gingival fibroblasts and antinflammatory effect of crude extract from mangosteen. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.15.

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Abstract:

Extract from mangosteen pericarp has demonstrated various pharmacological activities including anti-bacterial, anti-inflammatory and anti-fungal. It may have potential for the treatment of periodontal disease, which is a chronic inflammatory disease caused by anaerobic bacteria. The aim of this study was 1) to investigate the toxicity of mangosteen extract to human gingival fibroblast, 2) to examine the anti-bacterial activity of the extract against periodontopathic bacteria including P. gingivalis and A. actinomycetemcomitans, and 3) to examine the inhibitory effect of the extract on PGE[subs

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Mahanonda, Rangsini, Orawan Charatkulangkun, and Sathit Pichyangkul. The role of IL-17 in periodontitis. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.12.

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Background and objectives: IL-17 is a novel T cell-derived cytokine that promotes inflammatory responses. It is presence in inflamed gingival tissues and gingival crevicular fluid of periodontitis patients. In this study we investigated the effects of IL-17 alone or in combination with IFN-Y on the immune modulation of human gingival fibroblasts (HGFs) which would contribute to pathogenesis of periodontium. Methods and results: Various concentrations of IL-17, IFN-Y or the combination of these two cytokines were added to HGF cultures. The expression of ICAM-1, HLA-DR, and CD40 was assessed by

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