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Dissertations / Theses on the topic 'Periodontal cells'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

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1

Worapamorn, Wilairat. "Cell-surface proteoglycan expression by periodontal cells /." St. Lucia, Qld, 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16097.pdf.

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2

Gay, Isabel C. "Isolation and characterization of human periodontal ligament stem cells." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. http://www.mhsl.uab.edu/dt/2007m/gay.pdf.

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3

Stoianovici, Charles. "Directing Mesenchymal Stem Cells for Periodontal Regeneration." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5335.

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Background: Directing autogenous Mesenchymal Stem Cell (MSC) to defect sites has a great promise in bone regeneration. We designed a MSC specific, bone affinity peptide (E7HA7) by conjugating E7 with a polyglutamate hydroxyapatite (HA) binding motif. We sought to characterize the in-vivo releasing pattern and bioactivity of E7HA7. Methods: HA discs were coated with fluorescent labeled peptides E7HA7, E7HA2 or E7 were subcutaneously implanted in Sprague Dawley rats. In an ectopic bone formation model was used to test the in-vivo bioactivity of E7HA7 conjugated to DBM. Results: E7HA7 showed slow

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4

Winning, Lewis. "The osteogenic potential of periodontal ligament stem cells." Thesis, Queen's University Belfast, 2018. https://pure.qub.ac.uk/portal/en/theses/the-osteogenic-potential-of-periodontal-ligament-stem-cells(e5fdef0e-d55b-42b6-acb5-75a617b43edd).html.

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5

Campbell, Lauren Dee. "The role of CD4+ T cells in periodontal disease." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8241/.

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Introduction: Periodontal disease (PD) is the most common bone destructive chronic inflammatory disease in humans. Severe PD affects 8-15% of the population and impacts on the ability to chew and appearance, reduces quality of life, and is responsible for a substantial proportion of dental care costs. A dysbiotic oral biofilm is necessary but insufficient for development of PD. Rather, a dysregulated immune response to the disease-associated biofilm results in destruction of tooth supporting structures and eventual tooth loss. Despite the apparent involvement of the immune system in PD, clinic

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6

Åsman, Björn. "Juvenile periodontitis generation of free oxygen radicals and elastase by peripheral PMN cells /." Stockholm : Kongl. Carolinska Medico Chirurgiska Institutet, 1988. http://catalog.hathitrust.org/api/volumes/oclc/18171198.html.

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7

Engman, Sara. "Expression and Regulation of the Cell Surface Proteins CD47 and SIRPα in Resident Periodontal Cells". Thesis, Umeå universitet, Institutionen för odontologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-129258.

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Periodontal disease is an inflammatory disorder affecting the supporting tissues of the tooth. The inflammation triggers a destruction of the connective- and bone tissue surrounding the tooth, a process that is not fully elucidated. It is known that periodontitis shares features with other inflammatory disease like Crohn's disease and rheumatoid arthritis. The cell surface proteins signal regulatory protein alpha (SIRPα) and cluster of differentiation 47 (CD47) are important for the progression of the inflammation in rheumatoid arthritis and Crohn's disease. It has also been shown that lack of

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8

Bou, Chebel Najib. "Periodontal bacterial-DNA initiated immuno-inflammatory responses in human osteoblastic cells." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/97.

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Periodontitis is a chronic inflammatory disease initiated by gram negative anaerobic bacteria. These bacteria possess pathogen-associated molecular patterns (PAMPs) that interact with various receptors including Toll like receptors (TLRs). Bacterial DNA (bDNA) is one of the PAMPs mainly recognized by TLR9. Interaction of bDNA and its receptors leads to activation of inflammatory signaling pathways potentially resulting in periodontal bone destruction. The aim of this study was to determine the production of IL- 6 and IL-8 in response to periodontal bDNA from human osteoblastic cells (MG-

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9

Moore, Edward Andrew. "Cell attachment and spreading on physical barriers used in periodontal guided tissue regeneration /." Oklahoma City : [s.n.], 2002. http://library.ouhsc.edu/epub/theses/Moore-William-A.pdf.

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10

Wescott, David Clark, and n/a. "Osteogenic gene expression by human periodontal ligament cells under cyclic mechanical tension." University of Otago. School of Dentistry, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081202.131453.

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Background and objectives: The most widely accepted tooth movement model is defined by the pressure-tension hypothesis. An orthodontic force applied to a tooth generates areas of compression and tension in the periodontal ligament (PDL), which are transmitted to the alveolar bone. Areas of tissue exposed to tensile strain undergo bone deposition, whereas areas of tissue exposed to compressive strain undergo bone resorption. We propose that human PDL cells in monolayer culture exposed to tensile mechanical strain would express multiple genes involved in osteogenesis. Materials and Methods: Hu

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11

Nuersailike, Abuduwali [Verfasser]. "Characterization of Parathyroid Hormone 1 Receptor in Periodontal Ligament Cells / Abuduwali Nuersailike." Bonn : Universitäts- und Landesbibliothek Bonn, 2012. http://d-nb.info/1044080973/34.

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12

Almeida, Luciana Salles Branco de. "Influência da fluoxetina sobre a resposta imuno-inflamatória relacionada à doença periodontal." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288518.

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Orientadores: Pedro Luiz Rosalen, Gilson Cesar Nobre Franco<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-17T12:39:43Z (GMT). No. of bitstreams: 1 Almeida_LucianaSallesBrancode_D.pdf: 18183834 bytes, checksum: 7e68ca8a08aa330701eecf3a55349a69 (MD5) Previous issue date: 2011<br>Resumo: A fluoxetina é um droga inibidora seletiva da recaptação de serotonina que apresenta propriedades imunomoduladoras e antiinflamatórias. O objetivo desse estudo foi avaliar os efeitos da fluoxetina sobre a resposta imuno-inf

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13

Guimarães, Gustav [UNESP]. "Influência da extensão da doença periodontal no perfil sanguíneo de ratos Wistar." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/144733.

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14

Salmon, Richard J. "Prevalence of mast cells within the periodontal ligament of the developing rat molar /." Title page, contents and summary only, 2000. http://web4.library.adelaide.edu.au/theses/09DC/09dcs172.pdf.

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Thesis (D.Clin.Dent.)--University of Adelaide, Dental School, 2001.<br>Second copy has title: Prevalence and determination of mast cell type within the periodontal ligament of the developing rat tooth. Bibliography: leaves 109-119.

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15

Adams, A. M. "In vitro biocompatibility studies of dental restorative materials using human periodontal ligament cells." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287331.

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16

Martinez, Catalina. "The Effects of Dynamic Culturing Environments on Cell Populations Relevant to Heart Valve Tissue Engineering." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/505.

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The design of a tissue engineered pulmonary valve (TEPV) involves cells source(s), scaffold, in vitro conditioning system and the functional stability of the TEPV in vivo. Vascular cells (pulmonary artery smooth muscle (SMCs) and endothelial cells (ECs)) and periodontal ligament derived stem cells (PDLSCs) are relevant sources for the designing of TEPVs. In this study, labeling of these cell populations with super paramagnetic iron oxide microparticles along with concomitant usage of transfection agents was followed by visualization using magnetic resonance, while Intracellular iron oxide was

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17

Oliveira, Guilherme Henrique Costa 1988. "Avaliação do papel do marcador de superfície CD166 na diferenciação osteoblástica/cementoblástica de células mesenquimais indiferenciadas do ligamento periodontal de humanos." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290297.

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Orientador: Karina Gonzales Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-27T02:48:19Z (GMT). No. of bitstreams: 1 Oliveira_GuilhermeHenriqueCosta_M.pdf: 1623320 bytes, checksum: af95c8df2b95e735fcae950c2260eb9e (MD5) Previous issue date: 2015<br>Resumo: Células mesenquimais isoladas do ligamento periodontal (PDLSCs) de dentes humanos mostraram ser multipotentes e possuem a capacidade de se diferenciar em adipócitos osteoblastos in vitro. Além disso, possuem a capacidade de formar tec

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18

Pelaez, Daniel. "Role of Mechanical Strain on the Cardiomyogenic Differentiation of Periodontal Ligament Derived Stem Cells." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/573.

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The application of cellular therapies for the treatment of myocardial infarction has provided encouraging evidence for the possibility of cellular therapies to restore normal heart function. However, questions still remain as to the optimal cell source, pre-conditioning methods and delivery techniques for such an application. Here I propose the use of a unique population of stem cells arising from the embryonic neural crest. These cells were shown to express neural crest markers as well as pluripotency-associated markers. Furthermore, the cells were shown to express proteins essential to the

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19

Pöllänen, Marja. "Epithelial cell degeneration in the presence of bacteria and host derived factors associated with periodontal disease." Turku : Turun Yliopisto, 2000. http://books.google.com/books?id=xOlpAAAAMAAJ.

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20

Lin, Deborah G. "Storage conditions of avulsed teeth affect the phenotype of cultured human periodontal ligament cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0003/MQ45972.pdf.

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21

Lagerholm, Sara. "Isolation and Characterization of Mesenchymal Stem Cells from the Periodontal Ligament of Healthy Teeth." Thesis, Malmö universitet, Odontologiska fakulteten (OD), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19683.

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ABSTRAKT:Isolering och karaktärisering av mesenkymala stamceller från periodontalligamentet hos friskatänderSYFTE: Att isolera och odla celler från periodontalligamentet samt karaktärisera dem sommesenkymala stamceller.MATERIAL OCH METOD: Friska premolarer gjordes tillgängliga vid ortodontiskaextraktioner. Den mellersta 1/3 av periodontalligamentet skrapades varpå en enzymatiskmetod användes för isolering av individuella celler. Resulterande celler odlades understandardiserade metoder. Karaktärisering av celler skedde genom flödescymetri med 2 olikapaneler av cellyta markörer; en för etablerat

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22

Brito, Victor Gustavo Balera [UNESP]. "Papel dos mastócitos sobre o metabolismo ósseo local e sistêmico de ratos normotensos e hipertensos com doença periodontal." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/154428.

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Submitted by VICTOR GUSTAVO BALERA BRITO (victor_balera@hotmail.com) on 2018-07-03T00:06:47Z No. of bitstreams: 1 Dissertação Mestrado (Victor G B Brito) (FINAL).pdf: 4446716 bytes, checksum: 348cbec88d5fb2161f9d4aaa27992ac2 (MD5)<br>Approved for entry into archive by Ana Paula Rimoli de Oliveira null (anapaula@foa.unesp.br) on 2018-07-03T12:24:17Z (GMT) No. of bitstreams: 1 brito_vgb_me_araca_int.pdf: 4446716 bytes, checksum: 348cbec88d5fb2161f9d4aaa27992ac2 (MD5)<br>Made available in DSpace on 2018-07-03T12:24:17Z (GMT). No. of bitstreams: 1 brito_vgb_me_araca_int.pdf: 4446716 bytes, che

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23

Aidoukovitch, Alexandra. "Effects of strontium on osteogenic capacity and proliferation of human periodontal ligament cells and osteoblasts." Thesis, Malmö högskola, Odontologiska fakulteten (OD), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19681.

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Strontium (Sr2+) är det aktiva ämnet i läkemedel som används för att reducera frakturrisken hos patienter som lider av osteoporos. På senare tid har Sr2+ kombinerats med olika biomaterial i syfte att gynna benbildning, emellertid är ämnet vagt studerat avseende effekten på parodontala vävnader. Trots omfattande användning, är verkningsmekanismer av Sr2+ inte helt klarlagda. Denna studie syftar därmed till att utvärdera effekten av Sr2+ på humana parodontalligament-celler (PDL-celler) och osteoblaster avseende proliferation och osteogen aktivitet. Odlade humana PDL celler och osteoblastcellinje

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24

Carrió, Bertrán Neus. "Comparación del perfil proteico del ligamento periodontal versus el hueso alveolar con el complejo periodontal diferenciado a partir de las DPPSCs." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/461770.

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El tratamiento de los defectos infraóseos es uno de los objetivos de la terapia de la enfermedad periodontal. La literatura actual reporta ciertas limitaciones en cuanto a la predictibilidad de las técnicas, por consiguiente, siguen siendo necesarios modelos predictivos y estrategias regenerativas más precisas. Uno de los problemas actuales desde un punto de vista clínico, es el desconocimiento estructural de los tejidos que deseamos regenerar. Definir las proteínas expresadas en el periodonto podría ayudar a establecer estrategias clínicas regenerativas más fiables. El presente estudio

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25

Farag, Amro Ahmed Mahmoud. "Decellularized Tissue Engineered Constructs Using Cell Sheet Technology." Thesis, Griffith University, 2016. http://hdl.handle.net/10072/367720.

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The periodontium is a complex structure that is comprised of soft tissue components the gingiva and periodontal ligament, as well as hard tissue components in the form of alveolar bone and cementum. Human periodontal ligament cells (HPDLCs) and their extracellular matrix are regarded as essential components to achieve successful periodontal regeneration when treating periodontal lesions. In the present study, cell sheet technology was utilized to fabricate periodontal ligament cell sheets. These cell sheets were subsequently decellularized to isolate and preserve the extracellular component st

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26

Saito, Miki Taketomi 1986. "Caracterização do fenótipo de células mesenquimais indiferenciadas do ligamento periodontal de humanos com potencial para diferenciação osteoblásticas/cementoblástica." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289493.

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Orientador: Karina Gonzáles Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-22T14:42:06Z (GMT). No. of bitstreams: 1 Saito_MikiTaketomi_M.pdf: 1292081 bytes, checksum: 368c2e71f9e5362b6da282ee020ff058 (MD5) Previous issue date: 2013<br>Resumo: Vários estudos têm sido conduzidos com o intuito de isolar e caracterizar células com fenótipo mesenquimal indiferenciado a partir do ligamento periodontal de humanos e avaliar o seu potencial em promover a neoformação dos tecidos periodontais. A

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27

Rincon, Julio Cesar. "Expression of non-collagenous proteins by the epithelial rest cells of Malassez /." [Brisbane, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18072.pdf.

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28

Saoji, Nachiket A. "Effect of bisphosphonate on osteogenic differentiation of pulp and PDL cells." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/saoji.pdf.

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29

李晓 and Xiao Li. "Macrophage migration inhibitory factor and circulating progenitor cells: relevance and implications inperiodontal medicine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45894267.

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30

Mota, Patrícia Joana Soares. "Aplicação de células estaminais em Medicina Dentária." Master's thesis, [s.n.], 2012. http://hdl.handle.net/10284/3459.

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Trabalho apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária<br>Nos últimos anos têm-se realizado pesquisas sobre a utilidade de células estaminais em diversas áreas da saúde. Estes avanços científicos na área da bioengenharia tecidual têm levado ao desenvolvimento de novas terapias e curas de doenças que, até aos dias de hoje, não teriam cura. Recentes pesquisas têm revelado que os dentes são ótimas fontes de células estaminais. Tanto os dentes decíduos como permanentes têm células estaminais com grande potencial prolifera

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31

Belibasakis, Georgios N. "Cellular and molecular responses of periodontal connective tissue cells to Actinobacillus actinomycetemcomitans cytolethal distending toxin." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-345.

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32

El-Hossary, Wafaa Hassanein Hassan. "The effect of cyclic tensile strain on gene expression of cultured human periodontal ligament cells." Thesis, University of Leeds, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509041.

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Objectives: To analyse the changes in gene expression in a population of human periodontal ligament (HPDL) cells exposed to cyclic tensile strain in a three dimensional culture system. Results: Cells derived from extracted teeth were shown to represent a mixed population with greater than 95% of cells expressing markers characteristic of periodontal ligament fibroblasts with an oestobastic phenotype with a smaller sub-population (2-3%) of stem cells. Cells from several different donors were subjected to an applied tensile strain (5%) and compared to unstressed controls. RNA extracted immediate

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33

Al-Taweel, Firas Bashir Hashim. "The interaction of Porphyromonas gingivalis with host epithelial cells and its relevance to periodontal disease." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/17729/.

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Periodontitis is one of the most prevalent bacterial diseases affecting man with up to 90% of the global population affected. Its severe form can lead to the tooth loss in 10-15% of the population worldwide. The disease is caused by a dysbiosis of the local microbiota and one organism that contributes to this alteration in the bacterial population is Prophyromonas gingivalis. This organism possesses a range of virulence factors that appear to contribute to its growth and survival at a periodontal site amongst which is its ability to invade oral epithelial cells. Such an invasion strategy provi

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34

Vernon, Lauren Louise. "A Comparison of the Osteogenic Tissue Engineering Potential of Dental-Derived Stem Cell Lines: Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) vs. Periodontal Ligament Stem Cells (PERIOS)." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_theses/19.

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The goal of this study is to assess the osteogenic potential of two types of dental stem cell lines within a tissue engineering application. More specifically, the goal of this study is to find a readily abundant cell source with capacity to express an osteogenic phenotype. There are two parameters utilized to evaluate tissue engineering potential of cells: proliferation rate and differentiation potential. Briefly, proliferation rate is the speed at which cells divide and differentiation potential determines if cells are capable of committing towards specific lineages (e.g. osteogenic). The

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35

Freire, Isabelle Rodrigues [UNESP]. "Estudo dos mecanismos envolvidos na resposta tecidual de camundongos diabéticos com doença periodontal: papel dos mastócitos." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/95484.

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Made available in DSpace on 2014-06-11T19:27:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-02-13Bitstream added on 2014-06-13T20:36:16Z : No. of bitstreams: 1 freire_ir_me_araca.pdf: 351696 bytes, checksum: 8de9c54d57cecaf8154b65ccf640d4b9 (MD5)<br>O objetivo do presente estudo foi investigar o papel dos Mastócitos (MAST) na resposta tecidual de camundongos com Diabetes Mellitus (DM) submetidos a Doença Periodontal (DP). Os camundongos foram pré-tratados com uma dose única de estreptozotocina (STZ) para indução do DM. Para avaliar o papel dos MAST no controle da DP, os camundongo

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Soares, Diego Moura. "Influ?ncia da laserterapia na prolifera??o de c?lulas-tronco do ligamento periodontal humano." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17838.

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Made available in DSpace on 2014-12-17T15:43:54Z (GMT). No. of bitstreams: 1 DiegoMS_DISSERT.pdf: 1792102 bytes, checksum: 305ff686e7a1606e27026b528fd1d091 (MD5) Previous issue date: 2013-01-25<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Low level laser irradiation (LLLI) has been used in Dentistry to promote wound healing and tissue regeneration. The literature shows a positive effect of LLLI on cell proliferation, but little is known about their effectiveness in promoting stem cells proliferation. The aim of this study was to evaluate the effect of LLLI on the p

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Junior, Samuel de Barros Ferreira. "Modulação da severidade da doença periodontal experimental por células CCR5+." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25142/tde-02072009-112551/.

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As doenças periodontais (DP) afetam os tecidos de suporte dos dentes e são desencadeadas por micro-organismos gram-negativos anaeróbios presentes no biofilme periodontal. A evolução da doença é influenciada pela resposta inflamatória e imunológica do hospedeiro e envolve a participação de diversos tipos celulares, que atuam no micro ambiente local modulando a resposta do hospedeiro em busca do controle da infecção. Acredita-se que citocinas inflamatórias, quimiocinas e seus receptores estão envolvidos na migração celular para os tecidos periodontais, contudo, pouco se sabe sobre os mecanismos

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Freire, Isabelle Rodrigues. "Estudo dos mecanismos envolvidos na resposta tecidual de camundongos diabéticos com doença periodontal : papel dos mastócitos /." Araçatuba : [s.n.], 2009. http://hdl.handle.net/11449/95484.

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Orientador: Sandra Helena Penha de Oliveira<br>Banca: João Eduardo Gomes Filho<br>Banca: Ana Paula Campanelli<br>Resumo: O objetivo do presente estudo foi investigar o papel dos Mastócitos (MAST) na resposta tecidual de camundongos com Diabetes Mellitus (DM) submetidos a Doença Periodontal (DP). Os camundongos foram pré-tratados com uma dose única de estreptozotocina (STZ) para indução do DM. Para avaliar o papel dos MAST no controle da DP, os camundongos foram depletados de MAST pelo tratamento com composto 48/80. Subsequentemente foi realizada a indução da DP nos camundongos com DM e control

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39

Yilmaz, Ozlem. "Epithelial cell sensing and responses to P. gingivalis /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/6389.

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40

Coyac, Benjamin R. "Periodontal pathobiology and defective cell-autonomous mineralization in X-linked hypophosphatemia." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB006/document.

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Le rachitisme vitamino-résistant hypophosphatémique (RVRH) est une maladie génétique rare causée par des mutations du gène PHEX. La perte de fonction de la protéine PHEX conduit à l’augmentation du FGF23, une hormone circulante qui agit sur le rein et entraîne une perte systémique de phosphate. Le squelette rachitique des patients atteints de RVRH présente des déformations osseuses et une ostéomalacie. La dentine hypominéralisée des patients est à l’origine d’abcès dentaires fréquents, mais le statut parodontal des patients RVRH est mal connu, de même que leur risque de développer une parodont

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Albiero, Mayra Laino 1988. "Efeito do lipopolissacarídeo bacteriano sobre as propriedades biológicas das células mesenquimais indiferenciadas do ligamento periodontal de humanos." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289492.

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Orientador: Karina Gonzales Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-22T13:33:07Z (GMT). No. of bitstreams: 1 Albiero_MayraLaino_M.pdf: 1767389 bytes, checksum: 14c8bc6c823503f78c08850abc5ed95b (MD5) Previous issue date: 2013<br>Resumo: O objetivo do presente estudo foi avaliar se a exposição das células mesenquimais indiferenciadas do ligamento periodontal (PDLMSCs) ao lipopolissacarídeo da Porphyromonas gingivalis (Pg) e da Escherichia coli (Ec), levaria a alterações biológicas

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Pinkerton, Mark Neil, and n/a. "The molecular basis of orthodontic tooth movement : cytokine signaling by PDL cells in tension an in vitro study." University of Otago. School of Dentistry, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071207.161056.

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The pressure-tension hypothesis is the governing dogma of orthodontic tooth movement. This theory proposes that the application of loads to the crown of a tooth during orthodontic mechano-therapy results in differential site-specific reactionary strains in the para-dental tissues. Briefly, following the application of orthodontic load the bone and periodontal ligament (PDL) on one side of the tooth is placed in compression favoring bone resorption, while on the other side of the tooth they are placed in tension favoring osteogenesis The present in vitro model provides a surrogate for the PDL o

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Shaheen, Ibrahim Ahmed. "Studies of the effects of recombinant human bone morphogenetic protein-2 on human periodontal ligament cells in vitro." Thesis, Queen Mary, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267481.

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VECCHIATINI, Renata. "Mesenchymal stem cells from Wharton's Jelly and periodontal ligament: reliable not controversial sources for osteogenic differentiation and regenerative medicine." Doctoral thesis, Università degli studi di Ferrara, 2011. http://hdl.handle.net/11392/2388818.

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Mesenchymal stem cells (MSCs) are uniquely capable of crossing germinative layers borders (these cell populations are able to differentiate towards ectoderm-, mesoderm- and endoderm- derived lineages) and are viewed as promising cells for regenerative medicine approaches in several diseases. Some undoubtedly limiting factors for the clinical use of MSCs, i.e. for the repair of bone defects, are related to many different problems, that only partially today can be overcome through ex-vivo expansion and cells modification strategies. Considering MSCs sources, the use of fetal annexes-deriv

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Costa, Camila Alves. "Células tronco mesenquimais de medula óssea na regeneração periodontal. Prova de princípios - in vitro e in vivo." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/58/58132/tde-12072016-161505/.

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Estudos clínicos tem mostrado resultados satisfatórios na aplicação da matriz derivada de esmalte (MDE) nas superfícies radiculares. Porém, a completa regeneração de todos os tecidos periodontais perdidos permanece como um desafio. Na tentativa de alcançar esse objetivo o uso de células tronco mesenquimais derivadas de medula óssea (CTM-MO) em um veículo apropriado na engenharia tecidual vem sendo bastante estudada. Uma interessante aplicação da MDE seria como um mediador biológico específico para CTMMO no intuito de promover a diferenciação e proliferação celular e auxiliar nos processos de r

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Bittencourt, Marília da Silva Pereira. "A influência do tratamento periodontal não cirúrgico sobre o perfil lipídico e células sangüíneas de pacientes portadores de periodontite crônica generalizada." Universidade do Estado do Rio de Janeiro, 2008. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=3483.

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O objetivo deste estudo foi verificar se o tratamento periodontal não cirúrgico exercia alguma influência sobre o perfil lipídico, os elementos celulares das séries banca e vermelha do sangue, plaquetas e VHS de pacientes portadores de periodontite crônica generalizada. Dezoito pacientes, com média de idade de 50,6 anos ( 7,6), foram submetidos, previamente ao tratamento periodontal e 30 dias após o mesmo, à coleta de 10ml de sangue periférico, através do qual foram analisados o perfil lipídico, os elementos celulares das séries branca e vermelha, o número de plaquetas e VHS. Destes 18 pacien

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Fritz, Jason Ronald. "The Chondrogenesis of PDLs by Dynamic Unconfined Compression Is Dependent on p42/44 and Not p38 or JNK." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_theses/225.

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Articular cartilage lines the surfaces of load bearing joints and has limited capabilities for self-repair due to its alymphatic and avascular structure. Attempts at making repairs to this tissue has resulted in substandard materials and/or causing further injury to the patient making this tissue a prime candidate for tissue engineering studies incorporating adult stem cells. These studies have given rise to some answers and many more questions including a search for alternative stem cell sources and what biochemical changes the cells undergo during the differentiation of these stem cells into

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Philips, Julia Rachel. "B-1 And B-2 B Cell Responses To Lipopolysaccharide: Putative Roles In The Pathogenesis Of Periodontitis." Thesis, The University of Sydney, 2006. http://hdl.handle.net/2123/4395.

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Master of Science<br>Periodontal disease is one of the most widespread diseases in humans and is characterised by chronic gingival inflammation and B cell accumulation and resorption of the crest of alveolar bone with subsequent loss of teeth. Porphyromonas gingivalis has been identified as a putative aetiological agent for periodontitis. The aim of the research presented in this thesis was to investigate, using in vitro systems, the responses of autoreactive B-1 and B-2 cells to enterobacterial and nonenterobacterial lipopolysaccharide (LPS) to shed light on the pathogenesis of chronic period

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Philips, Julia Rachel. "B-1 and B-2 B cell responses to lipopolysaccharide putative roles in the pathogenesis of periodontitis /." University of Sydney, 2006. http://hdl.handle.net/2123/1852.

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Master of Science<br>Periodontal disease is one of the most widespread diseases in humans and is characterised by chronic gingival inflammation and B cell accumulation and resorption of the crest of alveolar bone with subsequent loss of teeth. Porphyromonas gingivalis has been identified as a putative aetiological agent for periodontitis. The aim of the research presented in this thesis was to investigate, using in vitro systems, the responses of autoreactive B-1 and B-2 cells to enterobacterial and nonenterobacterial lipopolysaccharide (LPS) to shed light on the pathogenesis of chronic period

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Alves, Luciana Bastos. "Expressão dos fenótipos fibroblástico e osteoblástico em culturas tridimensionais na presença de partículas de vidro bioativo." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/58/58132/tde-22102012-090829/.

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O objetivo deste estudo foi analisar a expressão dos fenótipos fibroblástico e osteoblástico em culturas tridimensionais na presença ou não de partículas de vidro bioativo. Fibroblastos derivados do ligamento periodontal humano (hPDLF) e células osteogênicas da calvária de rato recém-nascidos foram plaqueadas em superfícies bidimensionais - lamínulas de plástico ThermanoxTM (controle); superfícies colágenas bidimensionais - ThermanoxTM revestidas por colágeno I sem partículas de vidro bioativo (2D) e com partículas de vidro bioativo (2D+VB); e em gel colágeno tridimensional sem vidro bioativo

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