Relevant bibliographies by topics / Ph+ Acute Lymphoblastic Leukemia

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Ph+ Acute Lymphoblastic Leukemia'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Ph+ Acute Lymphoblastic Leukemia"

1

Maslak, P. "Ph+ Acute Lymphoblastic Leukemia." ASH Image Bank 2003, no. 1105 (2003): 100869. http://dx.doi.org/10.1182/ashimagebank-2003-100869.

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AKAY, Olga Meltem, and Betül Zeynep ERSOY. "Ph-like Acute Lymphoblastic Leukemia." LLM Dergi 2, no. 3 (2018): 53–59. http://dx.doi.org/10.5578/llm.67277.

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Tran, Thai Hoa, and Mignon L. Loh. "Ph-like acute lymphoblastic leukemia." Hematology 2016, no. 1 (2016): 561–66. http://dx.doi.org/10.1182/asheducation-2016.1.561.

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Abstract Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a newly identified high-risk (HR) B-lineage ALL subtype, accounting for ∼15% of children with National Cancer Institute–defined HR B-ALL. It occurs more frequently in adolescents and adults, having been reported in as much as 27% of young adults with ALL between 21 and 39 years of age. It exhibits adverse clinical features, confers a poor prognosis, and harbors a diverse range of genetic alterations that activate cytokine receptor genes and kinase signaling pathways, making it amenable to treatment with tyrosin
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Conserva, Maria Rosa, Immacolata Redavid, Luisa Anelli, et al. "IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?" International Journal of Molecular Sciences 24, no. 4 (2023): 3282. http://dx.doi.org/10.3390/ijms24043282.

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One key process that controls leukemogenesis is the regulation of oncogenic gene expression by transcription factors acting as tumor suppressors. Understanding this intricate mechanism is crucial to elucidating leukemia pathophysiology and discovering new targeted treatments. In this review, we make a brief overview of the physiological role of IKAROS and the molecular pathway that contributes to acute leukemia pathogenesis through IKZF1 gene lesions. IKAROS is a zinc finger transcription factor of the Krüppel family that acts as the main character during hematopoiesis and leukemogenesis. It c
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Tasian, Sarah K., Mignon L. Loh, and Stephen P. Hunger. "Philadelphia chromosome–like acute lymphoblastic leukemia." Blood 130, no. 19 (2017): 2064–72. http://dx.doi.org/10.1182/blood-2017-06-743252.

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AbstractPhiladelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares significant overlap with that of Ph-positive (Ph+) ALL and is suggestive of activated kinase signaling. Although Ph+ ALL is defined by BCR-ABL1 fusion, Ph-like ALL cases contain a variety of genomic alterations that activate kinase and cytokine receptor signaling. These alterations can be grouped into major subclasses that include ABL-class fusions involving ABL1, ABL2, CSF1R, and PDGFRB that phenocopy BCR-ABL1 and
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Kohla, Samah, Sarah EL Kourashy, Zafar Nawaz, Reda Youssef, Ahmad Al-Sabbagh, and Feryal A. Ibrahim. "P190BCR-ABL1 in a Patient with Philadelphia Chromosome Positive T-Cell Acute Lymphoblastic Leukemia: A Rare Case Report and Review of Literature." Case Reports in Oncology 14, no. 2 (2021): 1040–50. http://dx.doi.org/10.1159/000516270.

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T-acute lymphoblastic leukemia/lymphoblastic lymphoma (T-ALL/LBL) is rare and aggressive leukemia. Philadelphia chromosome positive (Ph+) is the most common cytogenetic abnormality in chronic myeloid leukemia (CML) and B-acute lymphoblastic leukemia (B-ALL). Ph+ T-ALL is exceeding rare and has a therapeutic and prognostic significance. The incidence and outcome of Ph+ T-ALL are unknown. Differentiation between Ph+ T-ALL/LBL and T-cell lymphoblastic crises of CML may be difficult. We report a rare case of adult de novo T-ALL with significant monocytosis, having Ph+ with (P190 <i>BCR-ABL1&
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Tran, Thai Hoa, and Sarah K. Tasian. "Clinical screening for Ph-like ALL and the developing role of TKIs." Hematology 2022, no. 1 (2022): 594–602. http://dx.doi.org/10.1182/hematology.2022000357.

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Abstract Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a common subtype of B-lineage acute lymphoblastic leukemia (B-ALL) with increasing frequency across the age spectrum. Characterized by a kinase-activated gene expression profile and driven by a variety of genetic alterations involving cytokine receptors and kinases, Ph-like ALL is associated with high rates of residual disease and relapse in patients treated with conventional chemotherapy. In this case-based review, we describe the biology of the 2 major ABL-class and JAK pathway genetic subtypes of Ph-like ALL
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De Vita, Serena, Silvia De Matteis, Luca Laurenti, et al. "Secondary Ph+ acute lymphoblastic leukemia after temozolomide." Annals of Hematology 84, no. 11 (2005): 760–62. http://dx.doi.org/10.1007/s00277-005-1093-6.

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Foà, Robin. "HOW I TREAT PH+ ACUTE LYMPHOBLASTIC LEUKEMIA." Hematology, Transfusion and Cell Therapy 47 (July 2025): 103869. https://doi.org/10.1016/j.htct.2025.103869.

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Vakana, Eliza, Jessica K. Altman, Heather Glaser, Nicholas J. Donato, and Leonidas C. Platanias. "Antileukemic effects of AMPK activators on BCR-ABL–expressing cells." Blood 118, no. 24 (2011): 6399–402. http://dx.doi.org/10.1182/blood-2011-01-332783.

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Abstract The mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in growth and survival of BCR-ABL transformed cells. AMPK kinase is a metabolic sensor that exhibits suppressive effects on the mTOR pathway and negatively regulates mTOR activity. We report that AMPK activators, such as metformin and 5-aminoimidazole-4-carboxamide ribonucleotide, suppress activation of the mTOR pathway in BCR-ABL–expressing cells. Treatment with these inhibitors results in potent suppression of chronic myeloid leukemia leukemic precursors and Ph+ acute lymphoblastic leukemia cells, inclu
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Dissertations / Theses on the topic "Ph+ Acute Lymphoblastic Leukemia"

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LIPKIN, VASQUEZ MARINA. "Unveiling the heterogeneity within chilhood Ph+ acute lymphoblastic leukemia." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/20633.

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In the past two decades, childhood acute lymphoblastic leukemia (ALL) cure rate has reached over 80% due to treatment advances, but some resistant ALL subtypes, such as those that carry the Philadelphia (Ph+) chromosome, still don’t respond to therapy. The presence of BCR-ABL in ALL children is correlated to a very poor prognosis, nevertheless, several long-scale studies have shown that Ph+ ALL is heterogeneous in terms of clinical parameters and patients respond differently to the therapy, what suggests the presence of additional mechanisms of leukemogenesis. A set of international studies wi
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Paganin, Maddalena. ""High Risk" Acute Lymphoblastic Leukemia." Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3427207.

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Acute lymphoblastic leukemia (ALL) is a neoplasia characterized by an abnormal, clonal and self-maintaining proliferation of lymphoid cells. In this three year of phd I tried to add some information to understand the complex molecular mechanisms underlying this disease. I performed my studies in the laboratory of "Oncoematologia Pediatrica, Dipartimento di Pediatria dell'Università  degli studi di Padova" and for three months in the laboratory of Prof. A. A. Ferrando, Columbia University, Irving Cancer Center, New York. The recombination, insertion and deletion of immunoglobulin (Ig) and T
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Kuchinskaya, Ekaterina. "Genetic studies of acute lymphoblastic leukemia /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-337-5/.

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Lo, Tony Chung Tung. "Inactivation of SHIP1 in acute lymphoblastic leukemia." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1465620.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed July 22, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 63-69).
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Kanerva, Jukka. "Prognostic factors in childhood acute lymphoblastic leukemia (ALL)." Helsinki : University of Helsinki, 2002. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/kanerva/.

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Oliveira, Tiago M. "The importance of glycosylation in Acute Lymphoblastic Leukemia." Thesis, Griffith University, 2021. http://hdl.handle.net/10072/410463.

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Acute leukemias, such as acute lymphoblastic leukemia (ALL), are aggressive cancers characterized by the rapid proliferation of malignant hematopoietic cells. Throughout the last 60 years, childhood ALL’s long-term survival rates increased from less than 10% to more than 90%. Despite these improvements, certain subtypes remain hard to manage (e.g. mixed lineage leukemia, MLL-r), and even new therapies frequently fail. Therefore, identifying leukemia-cell restricted antigens in these ALL subtypes remains crucial in the quest to develop novel diagnostic tools and specific treatments. Traditional
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卓大治 and Tai-chi Cheuk. "Childhood acute lymphoblastic leukaemia with TEL-AML1 gene fusion." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31969690.

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Cheuk, Tai-chi. "Childhood acute lymphoblastic leukaemia with TEL-AML1 gene fusion." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22264619.

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Akers, Stephen Matthew. "Modeling central nervous system involvement in acute lymphoblastic leukemia." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/11227.

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Thesis (Ph. D.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains x, 102 p. : ill. (some col.). Includes abstract. Includes bibliographical references.
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Thörn, Ingrid. "Minimal Residual Disease Assessment in Childhood Acute Lymphoblastic Leukemia." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-101028.

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Traditionally, response to treatment in hematological malignancies is evaluated by light microscopy of bone marrow (BM) smears, but due to more effective therapies more sensitive methods are needed. Today, detection of minimal residual disease (MRD) using immunological and molecular techniques can be 100 times more sensitive than morphology. The main aim of this thesis was to compare and evaluate three currently available MRD methods in childhood acute lymphoblastic leukemia (ALL): (i) real-time quantitative PCR (RQ-PCR) of rearranged antigen receptor genes, (ii) multicolor flow cytometry (FCM
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Books on the topic "Ph+ Acute Lymphoblastic Leukemia"

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Kato, Motohiro, ed. Pediatric Acute Lymphoblastic Leukemia. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-0548-5.

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Vora, Ajay, ed. Childhood Acute Lymphoblastic Leukemia. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39708-5.

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Carl, Pochedly, and Civin Curt I, eds. Childhood acute lymphoblastic leukemia. Saunders, 1990.

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Pullarkat, Vinod. Contemporary management of acute lymphoblastic leukemia. Jaypee Brothers Medical Publishers (P) Ltd, 2014.

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Litzow, Mark R., and Elizabeth A. Raetz, eds. Clinical Management of Acute Lymphoblastic Leukemia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85147-7.

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Vecchione, Severo. Acute lymphoblastic leukemia: Etiology, pathogenesis, and treatments. Nova Science Publishers, 2011.

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Secker-Walker, Lorna M. Chromosomes and genes in acute lymphoblastic leukemia. Springer, 1997.

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Escherich, Gabriele, and Valentino Conter, eds. Acute Lymphoblastic Leukemia in Children and Adolescents. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-71180-0.

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Saha, Vaskar, and Pamela Kearns, eds. New Agents for the Treatment of Acute Lymphoblastic Leukemia. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-8459-3.

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Saha, Vaskar, and Pamela Kearns. New agents for the treatment of acute lymphoblastic leukemia. Springer, 2011.

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Book chapters on the topic "Ph+ Acute Lymphoblastic Leukemia"

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Tran, Thai Hoa, and Sarah K. Tasian. "Treatment of Ph-Like Acute Lymphoblastic Leukemia." In Clinical Management of Acute Lymphoblastic Leukemia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85147-7_10.

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Tran, Thai Hoa, and Sarah K. Tasian. "Management of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia (Ph-Like ALL)." In Pathogenesis and Treatment of Leukemia. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-3810-0_23.

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Bassan, Renato, Ama Z. S. Rohatiner, Alessandro Rambaldi, et al. "Clinical Sensitivity to Anthracyclines in PH/BCR+ Acute Lymphoblastic Leukemia." In Drug Resistance in Leukemia and Lymphoma III. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4811-9_53.

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Martin, H., N. Goekburget, J. Atta, W. D. Ludwig, and D. Hoelzer. "Treatment of Ph+ and t(4;11)+ Acute Lymphoblastic Leukemia in Adults." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-71960-8_103.

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Lerma, E., L. Celesti, A. Dejana, and A. M. Carella. "Philadelphia (Ph)-Chromosome-Negative Peripheral Blood Stem Cells can be Mobilized in the Early Phase of Recovery after a Myelosuppressive Chemotherapy in Ph-Chromosome-Positive Acute Lymphoblastic Leukemia." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-71960-8_104.

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Ribera, Josep-Maria. "Acute Lymphoblastic Leukemia." In HIV-associated Hematological Malignancies. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26857-6_11.

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Cunningham, Jacqueline L., and Carol L. Armstrong. "Acute Lymphoblastic Leukemia." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_85.

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Zakout, Ghada, and Adele K. Fielding. "Acute lymphoblastic leukemia." In Clinical Manual of Blood and Bone Marrow Transplantation. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119095491.ch10.

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Wynn, Robert F. "Acute Lymphoblastic Leukemia." In Pediatric Hematology and Oncology. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444315134.ch7.

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McNeer, Jennifer L., Archie Bleyer, Valentino Conter, and Wendy Stock. "Acute Lymphoblastic Leukemia." In Cancer in Adolescents and Young Adults. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33679-4_7.

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Conference papers on the topic "Ph+ Acute Lymphoblastic Leukemia"

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K, Lalithkumar, Naveen Raj B, Priyanga M. A, Sandhya S, and Karthiga M. "CapsENet: Deep Learning based Acute Lymphoblastic Leukemia Detection Approach." In 2024 8th International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud) (I-SMAC). IEEE, 2024. http://dx.doi.org/10.1109/i-smac61858.2024.10714671.

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Prasad, Prakeerth, and Jani Anbarasi L. "Acute Lymphoblastic Leukemia Subtypes Detection using Vision Transformer Model." In 2024 5th International Conference on Data Intelligence and Cognitive Informatics (ICDICI). IEEE, 2024. https://doi.org/10.1109/icdici62993.2024.10810888.

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Swain, K. P., S. K. Swain, and S. R. Nayak. "Vision Transformer-Based Automated Classification of Acute Lymphoblastic Leukemia." In 2025 International Conference on Emerging Systems and Intelligent Computing (ESIC). IEEE, 2025. https://doi.org/10.1109/esic64052.2025.10962707.

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P, Muhammad Shameem, Jemsheer Ahmed P, Nisa Parvin K. P, Safa M. T, Sahana V. P, and Hima Musthafa T. H. "Enhancing Acute Lymphoblastic Leukemia Diagnosis Through Dual Deep Learning Approaches." In 2024 IEEE Recent Advances in Intelligent Computational Systems (RAICS). IEEE, 2024. http://dx.doi.org/10.1109/raics61201.2024.10689773.

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Munna, Mohmmad Mehedi Hasan, Iqbal Habib, Nakib Aman Turzo, Nasrin Jahan, and Sabiha Nusrat. "Automated Diagnosis of Acute Lymphoblastic Leukemia Leveraging EfficientNet and Fastai." In 2024 27th International Conference on Computer and Information Technology (ICCIT). IEEE, 2024. https://doi.org/10.1109/iccit64611.2024.11021950.

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Ahmadsaidulu, Shaik, Akash Suresh Kanase, Puneet Kumar Jain, and Earu Banoth. "A Novel Deep Learning Framework for Enhanced Acute Lymphoblastic Leukemia Detection." In Frontiers in Optics. Optica Publishing Group, 2024. https://doi.org/10.1364/fio.2024.jw5a.39.

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In this work a deep-learning model using enhanced YOLOv8(You Only Look Once) for classifying Acute Lymphoblastic Leukemia (ALL) and other normal cells. Achieving 98% accuracy for ALL and 91% for combined (ALL &amp; Normal) classification enhances clinical decision-making.
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Soni, Dhruv Kumar, Ashu Taneja, Komuravelly Sudheer Kumar, and Mohammed I. Habelalmateena. "Deep Learning-Driven Classification of Acute Lymphoblastic Leukemia Subtypes Using CNNs." In 2025 IEEE International Conference on Interdisciplinary Approaches in Technology and Management for Social Innovation (IATMSI). IEEE, 2025. https://doi.org/10.1109/iatmsi64286.2025.10984536.

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Munna, Mohammad Mehedi Hasan, Iqbal Habib, and Nakib Aman. "A Novel Hybrid Xception-DenseNet121 Model for Acute Lymphoblastic Leukemia Classification." In 2024 6th International Conference on Sustainable Technologies for Industry 5.0 (STI). IEEE, 2024. https://doi.org/10.1109/sti64222.2024.10951150.

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Roberts, Kathryn G., Yongjin Li, Debbie Payne-Turner, et al. "Abstract 3083: The genetic landscape of Ph-like acute lymphoblastic leukemia." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3083.

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Duy, Cihangir, Christian Hurtz, Phillip H. Koeffler, Ari M. Melnick, and Markus Müschen. "Abstract LB-235: BCL6 enables Ph+ acute lymphoblastic leukemia cells to survive BCR-ABL1 kinase inhibition." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-235.

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Reports on the topic "Ph+ Acute Lymphoblastic Leukemia"

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Ferrando, Adolfo A. Targeting Class I PI3Ks in the Treatment of T-cell Acute Lymphoblastic Leukemia. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada591435.

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Brinker, C. Jeffrey, and Mekensey Buley. Identification and display of CRLF2 ligands for targeted nanoparticle delivery to acute lymphoblastic leukemia. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1051698.

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Xiang, Qi, and Yuping Zhang. The Influence of pegaspase on coagulation function and remission rate in adult patients with acute lymphoblastic leukemia. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.7.0016.

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Liu, Hengxu, and Jiong Luo. The impact of physical exercise intervention on children with acute lymphoblastic leukemia: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.9.0100.

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Ponvilawan, Ben, Pongthep Vittayawacharin, Pattaraporn Tunsing, and Weerapat Owattanapanich. Efficacy of Targeted Immunotherapy as Induction or Salvage Therapy in Acute Lymphoblastic Leukemia: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.7.0011.

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Lee, Yeonhong, Eun Jeong Jang, Ha-Young Yoon, Jeong Yee, and Hye-Sun Gwak. Effect of ITPA polymorphism on adverse drug reactions of 6-mercaptopurine in pediatric patients with acute lymphoblastic leukemia: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0110.

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Gao, Xiaohui, Hui Zeng, Fei Sun, et al. Comparing therapeutic effects of hematopoietic stem cell transplantation, tyrosine kinase inhibitors and chemotherapy for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.5.0012.

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