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Dissertations / Theses on the topic 'Pharmaceutical residue'

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1

Pule, Bellah Oreeditse. "Solid-phase extraction based sample preparation for the determination of drug and organic pollutant residue." Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1006711.

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This thesis presents solid phase extraction (SPE) methodologies based on mixed-mode polymeric sorbents; a mixed mode strong anion exchanger (Agilent SampliQ SAX) and a mixed mode strong cation exchanger (Agilent SampliQ SCX). Furthermore, dispersive-SPE based on a quick, easy, cheap, effective, rugged and safe (QuEChERS) method was assessed for applicability in the determination of drug residues. The mixed-mode polymeric sorbents were evaluated for the simultaneous fractionation of drugs that exhibit diverse polarities with acidic, basic and neutral functionalities in biological matrices (plas
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2

Batlokwa, Bareki Shima. "Development of molecularly imprinted polymer based solid phase extraction sorbents for the selective cleanup of food and pharmaceutical residue samples." Thesis, Rhodes University, 2012. http://hdl.handle.net/10962/d1004967.

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This thesis presents the development of chlorophyll, cholic acid, aflatoxin B1 molecularly imprinted polymer (MIP) particles and cholic acid MIP nanofibers for application as selective solid phase extraction (SPE) sorbents. The particles were prepared by bulk polymerization and the nanofibers by a novel approach combining molecular imprinting and electrospinning technology. The AFB1 MIP particles were compared with an aflatoxin specific immunoextraction sorbent in cleaning-up and pre-concentrating aflatoxins from nut extracts. They both recorded high extraction efficiencies (EEs) of > 97 % in
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3

Goralski, Alma. "Removal of pharmaceutical residues from wastewater." Thesis, KTH, Skolan för kemi, bioteknologi och hälsa (CBH), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-259951.

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Today, pharmaceutical residues are widely found in nature as a cause of the extensive use of human and veterinary medicine. The pharmaceutical residues have shown to have a damaging impact on flora and fauna. Wastewater Treatment Plants (WWTPs), today, are not designed for pharmaceutical removal, which calls for new methods and the implementation of these to avoid increased concentrations of pharmaceutical residues in nature. This thesis addresses three main areas. Firstly, a pre-study regarding the prevalence of pharmaceutical residues at different parts of a WWTP and in the nearby river, sec
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4

Chu, Jhih-Wei 1973. "Oxidation of methionine residues in protein pharmaceuticals." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28660.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2004.<br>Includes bibliographical references (p. 171-189).<br>(cont.) of free methionine. Therefore, the environments surrounding different methionine sites in G-CSF mainly provide spatial restriction to the access to the solvent but do not affect oxidation in a specific manner, consistent with the good correlation between 2SWCN's and the rates of oxidation. A comprehensive picture of oxidation is thus developed. It allows an accurate prediction of protein oxidation, and provides a rationale for developing s
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5

Buratti, Sara <1981&gt. "Pharmaceutical residues in aquatic systems: mode of action and effects on mussel physiology." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3539/1/Buratti_Sara_tesi.pdf.

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Pharmaceutical residues contaminate aquatic ecosystems as a result of their widespread human and veterinary usage. Since continuously released and not efficiently removed, certain pharmaceuticals exhibit pseudo-persistence thus generating concerns for the health of aquatic wildlife. This work aimed at assessing on mussels Mytilus galloprovincialis, under laboratory conditions, the effects of three pharmaceuticals, carbamazepine (antiepileptic), propranolol (β-blocker) and oxytetracycline (antibiotic), to evaluate if the human-based mode of action of these molecules is conserved in invertebrat
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6

Buratti, Sara <1981&gt. "Pharmaceutical residues in aquatic systems: mode of action and effects on mussel physiology." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3539/.

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Pharmaceutical residues contaminate aquatic ecosystems as a result of their widespread human and veterinary usage. Since continuously released and not efficiently removed, certain pharmaceuticals exhibit pseudo-persistence thus generating concerns for the health of aquatic wildlife. This work aimed at assessing on mussels Mytilus galloprovincialis, under laboratory conditions, the effects of three pharmaceuticals, carbamazepine (antiepileptic), propranolol (β-blocker) and oxytetracycline (antibiotic), to evaluate if the human-based mode of action of these molecules is conserved in invertebrat
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7

Wesström, Therese, and Jenny Andersson. "Pharmaceutical pollution in irrigation water : A Minor Field Study in Chirapatre Estates in Kumasi, Ghana." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-244849.

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In Ghana, wastewater is frequently used as a source of irrigation water for crops in urban areas, due to water scarcity and an increasing population growth. The water contains high amounts of nutrients, but also other unwanted constituents such as heavy metals, pathogens and pharmaceutical residues and is a potential health risk for the consumers. This study aimed to determine the status of pharmaceutical pollution in irrigation water used in Chirapatre Estates, a suburb to Kumasi, Ghana. Chirapatre Estates is located on a hill sloping towards a stream, with a network of sewer lines connected
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8

Winker, Martina. "Pharmaceutical residues in urine and potential risks related to usage as fertiliser in agriculture." Hamburg [TuTech Innovation], 2009. http://d-nb.info/994334494/34.

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9

Fornander, Erik. "Ozone Treatment Targeting Pharmaceutical Residues : Validation and Process Control in a Wastewater Treatment Plant." Thesis, Linköpings universitet, Teknisk biologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154012.

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Major studies conducted in Europe and North America has concluded that the current processes in wastewater treatment plants insufficiently degrade micropollutants e.g. pharmaceutical residues. Several sorption and oxidation methods has therefore been investigated with the purpose of removing or degrading micropollutants in wastewater. The main purpose of this project was, firstly, to validate the results from a pilot study conducted by Tekniska verken i Linköping AB (2014) which investigated the use of ozone to degrade pharmaceutical residues. Secondly, to investigate and design a suitable pro
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10

Maciel, Edvaldo Vasconcelos Soares. "Síntese de novos materiais à base de grafeno para aplicação em microextração por sorvente empacotado MEPS na extração de tetraciclinas presentes no leite com posterior análise por cromatografia líquida acoplada a espectrometria de massas sequencial ." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-07022018-103749/.

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O crescimento da população mundial e a expansão industrial são fatores que atualmente desencadeiam um aumento no consumo de produtos e geração de resíduos. Frequentemente utilizados na medicina tradicional e veterinária, os antibióticos são classificados como uma classe emergente de poluentes, pois, devido à sua baixa taxa de degradação e à ineficácia dos sistemas de tratamentos de água, encontram-se disseminados no meio ambiente e nos alimentos. Em consequência desse fato, estudos para o desenvolvimento de novos materiais e métodos que removam estes contaminantes utilizando menor quantidade d
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11

Winker, Martina [Verfasser]. "Pharmaceutical residues in urine and potential risks related to usage as fertiliser in agriculture / Martina Winker." Hamburg : [TuTech Innovation], 2009. http://d-nb.info/994334494/34.

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12

Sane, Nini. "Evaluation de l'efficacité du traitement des effluents domestiques par un pilote d'assainissement autonome." Electronic Thesis or Diss., Bordeaux 3, 2024. http://www.theses.fr/2024BOR30050.

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Ce projet de thèse vise la mise en place d’un système d’assainissement autonome écologique et économique répondant aux normes sanitaires nationales mais aussi la valorisation des déchets solides et liquides issues des ménages dans le secteur agricole. Il entre dans le cadre des objectifs de développement durable (ODD) notamment le point numéro 6 concernant l’accès à l’eau et à l’assainissement pour tous. Une filière d’assainissement autonome a été installé à Keur Moussa dans la région de Thiès au Sénégal. Cette filière dimensionnée pour une maison individuelle pouvant loger jusqu’à 12 habitant
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13

Reinholds, I., I. Pugajeva, I. Perkons, J. Rusko, and V. Bartkevics. "Efficiencies of conventional anaerobic digestion procedure and ionizing radiation treatment for removal of pharmaceutical residues from municipal wastewater." Thesis, Sumy State University, 2016. http://essuir.sumdu.edu.ua/handle/123456789/52149.

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Nowadays, pharmaceutical products (PPs) have raised global concerns due to accumulation of their residues in aquatic ecosystems. In the urban environment, epidemics and social factor illnesses, advancement of pharmaceutical industry, hospitals and other health-care institutions, veterinary institutions pharmaceutical industries and uses in household need are the main economic sources or factors influencing emerging dissemination of PPs in the environment.
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14

Gulde, Andreas. "Quantitative analysis of multi- pharmaceutical residues : examining the efficiency of ozonation as wastewater treatment method, removing potential toxic agents." Thesis, Umeå universitet, Kemiska institutionen, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124797.

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15

Tuckwell, Rebecca. "The impact on receiving waters of pharmaceutical residues and antibiotic resistant faecal bacteria found in urban waste water effluents." Thesis, Middlesex University, 2015. http://eprints.mdx.ac.uk/18521/.

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Pharmaceuticals intended for human use are frequently detected in the aquatic environment. This is predominantly from their excretion following ingestion and subsequent discharge in domestic sewage. Wastewater treatment provides an opportunity to control their release to surface waters however, their removal is often incomplete. This thesis addresses this pharmaceutical pathway and the potential impact on the aquatic environment. The progress of bezafibrate, carbamazepine, ciprofloxacin and clarithromycin were monitored through the treatment stages (screened sewage, settled sewage and final ef
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16

Feng, Ling, and Ling Feng. "Advanced oxidation processes for the removal of residual non-steroidal anti-inflammatory pharmaceuticals from aqueous systems." Phd thesis, Université Paris-Est, 2013. http://tel.archives-ouvertes.fr/tel-00952080.

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The thesis mainly focused on the implementation of advanced oxidation processes for the elimination of three non-steroidal anti-inflammatory drugs-ketoprofen, naproxen and piroxicam in waters. The three compounds are among the most used medicines, whose presence in waters poses a potential ecotoxicological risk. Due to the low pharmaceuticals removal efficiency of traditional wastwater treatement plants, worldwide concerns and calls are raised for efficient and eco-friendly technologies. Advanced oxidation processes, such as ozonation-biofiltration, electro-Fenton and anodic oxidation processe
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Feng, Ling. "Advanced oxidation processes for the removal of residual non-steroidal anti-inflammatory pharmaceuticals from aqueous systems." Thesis, Paris Est, 2013. http://www.theses.fr/2013PEST1109/document.

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La thèse a porté principalement sur la mise en œuvre de procédés d'oxydation avancée permettant l'élimination de trois anti-inflammatoires non stéroïdiens, le kétoprofène, le naproxène et le piroxicam dans l'eau. Ces trois composés sont parmi les médicaments les plus utilisés, dont la présence dans les eaux naturelles présente potentiellement un risque toxicologique. En raison de la faible efficacité d'élimination des produits pharmaceutiques par les stations traditionnels de traitement des eaux usées, les scientifiques se sont mis à la recherche de technologies de traitements efficaces et res
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18

Svobodová, Dagmar. "Chirální analýza residuí léčiv v odpadních vodách." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-216766.

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The theoretical part shortly describes chirality with focus on chiral pharmaceuticals. The processes of their absorption, distribution, metabolism and elimination in human body are discussed. These points are very important to understand possible fate of chiral drugs in the environment as there is only little data concerning their environmental behaviour. The occurrence and enantioselective toxicity of chiral drugs is also discussed here. One of the chapters describes non-steroidal anti-inflammatory drugs, as they are analyzed in the wastewater in the experimental part, and their occurrence in
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19

Engberg, Erica, and Emilia Johansson. "Ozonation of pharmaceutical residues in a wastewater treatment plant : Modeling the ozone demand based on a multivariate analysis of influential parameters." Thesis, Linköpings universitet, Teknisk biologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-151565.

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Most pharmaceutical residues in wastewater treatment plants (WWTPs) end up in the hydrosphere where they cause negative effects on the aquatic life and might disrupt ecosystems. By implementing an ozonation step (treatment with ozone) in the wastewater treatment process, these pharmaceutical residues can be reduced.  The purpose of this project was to verify that the ozonation process works in full-scale, thereby verifying a pilot study conducted in 2014 at Tekniska Verken i Linköping AB (TVAB). Additionally, the purpose was to investigate which parameters influence the ozone demand in order t
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20

Banaschik, Robert [Verfasser]. "Potential of Pulsed Corona Discharges Generated in Water for the Degradation of Recalcitrant Pharmaceutical Residues and for Water Disinfection / Robert Banaschik." Greifswald : Universitätsbibliothek Greifswald, 2017. http://d-nb.info/1147900051/34.

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21

Lacina, Petr. "Využití plynové chromatografie pro stanovení reziduí léčiv ve vodách." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2009. http://www.nusl.cz/ntk/nusl-216479.

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Diploma thesis is focused on the choose of methods and optimalisation analysis procedure of selected pharmaceuticals (salicylic acid, ibuprofene, naproxene, ketoprofene and diclofenac) in surface and waste water by using gas chromatography with mass spectrometer (GC-MS). Solid-phase extraction (SPE) with Oasis HLB cartridges was used as an extraction method in this analysis. Extraction is followed by derivatization and their optimalization of selected pharmaceuticals. Derivatization and its optimalization were performed by two silylation reagens N-methyl-N-(trimethylsilyl)trifluoroacetamide (M
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22

Sýkora, Richard. "Využití GC/MS při analýze léčiv." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-216709.

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This diploma thesis is based on the current issue of the presence of pharmaceuticals in various components of the environment. Concerning the contamination by residues of pharmaceuticals the most affected environment is the aquatic environment where these substances leaks especially from wastewater treatment plants, which eliminate them during the cleaning process only partially. This work is focused on the selected group of pharmaceuticals, non-steroidal anti-inflammatory drugs (salicylic acid, ibuprofen, caffeine, naproxen, ketoprofen, diclofenac) in waste water. For analysis purposes two ty
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23

BOBBA, SERENA. "Near-Infrared Spectroscopy for Freeze-Drying: Applications for Pharmaceuticals." Doctoral thesis, Politecnico di Torino, 2022. http://hdl.handle.net/11583/2957736.

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24

Ademoyegun, Olufemi Temitope. "Evaluation of some pharmaceutical and personal care products and pesticide residues in selected wastewater treatment plants and receiving watersheds in Eastern Cape, South Africa." Thesis, University of Fort Hare, 2017. http://hdl.handle.net/10353/2922.

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Emerging organic contaminants (EOCs) have been the focus of global environmental research for over three decades. EOCs have caused widespread concern due to their extensive use. As EOCs were designed to correct, enhance or protect a specific physiological, their target effects in humans and/or farm stocks are relatively well known and documented. However, there is limited knowledge about their unintended effects in the environment. To address the occurrence, distribution and fate of EOCs in the environment, efficient and reliable analytical methods are needed. The relatively low concentration,
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Kolli, Ramya. "Effect of Leaving Ligands of Platinum(II) Diamine Complexes on DNA and Protein Residues." TopSCHOLAR®, 2013. http://digitalcommons.wku.edu/theses/1268.

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Platinum compounds are widely used drugs in cancer treatments. Although DNA is the biological target, reaction of platinum compounds with proteins is also potentially significant. Our objective is to study the effects of leaving ligands on the relative reactivity between 5'-GMP (guanosine 5' phosphate), a key DNA target, and N-Acetyl - L-Methionine (N-AcMet), a key protein target. We have used NMR spectroscopy to monitor reactions with N-AcMet and 5'-GMP added to a platinum complex to see which products are formed preferentially. Previous research showed that both a non-bulky complex such as [
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26

Söderbom, Olsson Tobias. "AN EVALUATION OF PHARMACEUTICAL REMOVAL TECHNOLOGIES AND BUSINESS MODEL STRATEGIES : FROM A WASTE WATER TREATMENT PLANT AND SUPPLIER PERSPECTIVE." Thesis, Karlstads universitet, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-78869.

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Pharmaceutical residues are passing our wastewater treatment plants and flowing out in to the nature. The medical substances are built to affect different processes in our bodies, but also affect other species and increase the risk of developing multi resistant bacterial strains, not curable with antibiotics. This has made wastewater treatment plants (WWTPs) interested in investing in pharmaceutical removal. This study describes what criteria that are important to consider when choosing technology for pharmaceutical removal, and presents a model for the WWTPs to use when choosing pharmaceutica
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Paiva, Cláudia Cristina Sousa de. "CONTAMINANTES AMBIENTAIS PRESENTES EM ATIVIDADES DIDÁTICO-EXPERIMENTAIS EM CURSOS DE FARMÁCIA: IDENTIFICAÇÃO E PROPOSTA DE GESTÃO." Pontifícia Universidade Católica de Goiás, 2017. http://tede2.pucgoias.edu.br:8080/handle/tede/3633.

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Submitted by admin tede (tede@pucgoias.edu.br) on 2017-03-30T13:39:02Z No. of bitstreams: 1 CLÁUDIA CRISTINA SOUSA DE PAIVA.pdf: 2910049 bytes, checksum: cbbd52d134cd09ce88ce0b663df5e6aa (MD5)<br>Made available in DSpace on 2017-03-30T13:39:02Z (GMT). No. of bitstreams: 1 CLÁUDIA CRISTINA SOUSA DE PAIVA.pdf: 2910049 bytes, checksum: cbbd52d134cd09ce88ce0b663df5e6aa (MD5) Previous issue date: 2017-01-30<br>The waste generated in the various human activities must be treated and disposed of properly, which poses a great challenge to public and private administration, especially in urban center
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Filipsson, Ingela. "Latrin som substrat vid rötning : utvärdering av biogaspotential och reduktion av läkemedelsrester." Thesis, Institutionen för energi och teknik, SLU, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-263077.

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Avloppsvatten innehåller näring, bland annat kväve och fosfor som kan orsaka övergödningom det kommer ut i sjöar och vattendrag. Samtidigt behöver stora mängder näringsämnen tillföras i jordbruket för att producera mat. Ett sätt att effektivt ta till vara på näringen i avlopp och återföra den till jordbruket skulle kunna vara källsortering av avlopp. På så sätt samlas näringsämnena i en mindre volym och blandas inte med bad-, disk-, och tvättvatten. Examensarbetet syftade till att undersöka rötning som behandlingsmetod och teknik för att utnyttja energin i latrin. I rötning bryter mikroorganis
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Pouzol, Tanguy. "Monitoring and modelling of pharmaceuticals in wastewater : Daily and hourly loads in both hospital and urban wastewater." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEI009/document.

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Les flux journaliers et horaires de 15 molécules pharmaceutiques à l'entrée d'une station d'épuration ont été mesurés sur 3 ans et modélisés à la fois pour un bassin urbain de 16 000 habitants et un hôpital de 450 lits. Certaines molécules ne sont jamais ou rarement quantifiées. Les flux journaliers vont de 0,6 à 564 g/jour en fonction de la molécule et de la campagne de mesure 24h. Aucune dynamique saisonnière ou hebdomadaire n’a été identifiées. La dynamique des flux horaires des médicaments se distingue des autres polluants et du débit des eaux usées. Les flux horaires mesurés sont sévèreme
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Souza, Edivaldo Luis de 1968. "Emprego de material nanoestruturado sobre Ti na degradação de fármacos = Use of nanostructured titanium dioxide for treatment of pharmaceuticals." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/267729.

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Orientadores: Peterson Bueno de Moraes, Christiane de Arruda Rodrigues Ragnini<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Tecnologia<br>Made available in DSpace on 2018-08-27T04:30:52Z (GMT). No. of bitstreams: 1 Souza_EdivaldoLuisde_M.pdf: 3079610 bytes, checksum: a78db6078a721c74f963b944bae72f47 (MD5) Previous issue date: 2015<br>Resumo: A sociedade e seus processos produtivos têm gerado e lançado quantidades elevadas e diversificadas de compostos orgânicos, inorgânicos e biológicos no meio ambiente. Juntamente com as emissões naturais, houve um grande acúm
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Semrany, Samer. "Bioaugmentation fongique des boues activées : élimination de la carbamazépine persistante dans l’eau." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S184/document.

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Les résidus pharmaceutiques sont considérés comme un problème écologique émergent, à cause de leur présence et leur accumulation continue dans l’environnement. Même à des faibles concentrations, ces substances sont susceptibles de menacer l’ensemble des organismes vivants. Il est donc, urgent de développer les moyens techniques permettant leur élimination. Dans ce cadre s’inscrit le travail de cette thèse, il a pour objectif de traiter la carbamazépine, un antiépileptique largement détecté dans le milieu aquatique. Une première étude a été menée sur la biodégradation de la carbamazépine par de
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Gomes, Paulo Clairmont Feitosa de Lima. "Desenvolvimento e aplicação de técnicas miniaturizadas de preparo de amostra na determinação de fármacos no ambiente." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-10102012-145948/.

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A presença de fármacos no ambiente é um problema preocupante em virtude dos efeitos ecotoxicológicos conhecidos, e ainda os que continuam desconhecidos. A água é um dos compartimentos ambientais mais afetado por esses contaminantes, já que é utilizado em diversas atividades humanas. A contaminação da água afeta não somente os humanos, mas também todos os demais seres vivos que vivem ou utilizam dessa água. Por esse motivo, o desenvolvimento de métodos para análise de medicamentos em matrizes ambientais é essencial para o monitoramento desses contaminantes. Além disso, os métodos já desenvolvid
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Palmer, Corianna. "Fentanyl transdermal patches: Extraction optimization and evaluation of a novel disposal method using NarcX®." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1616968376783083.

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Hamon, Pierre. "Traitement des effluents d’un service d’oncologie par bioréacteur à membranes : faisabilité d’acclimatation et gain apporté sur l’élimination de molécules médicamenteuses." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4328/document.

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Si les risques liés à la présence de résidus médicamenteux dans l'environnement sont encore méconnus, les premiers cas avérés et l'introduction récente de trois médicaments (2013) sur une liste de surveillance de l'UE imposent d'ores et déjà le développement de procédés de traitement capables d'éliminer cette pollution spécifique. C'est dans ce contexte que le traitement des effluents d'un service d'oncologie par un bioréacteur à membranes a été évalué dans cette thèse. Les effluents collectés sont caractérisés par une importante variabilité de la charge polluante et des concentrations médicam
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Souza, Neyliane Costa de. "DeterminaÃÃo de Micropoluentes Emergentes em Esgoto SanitÃrio, Hospitalar e Ãguas Superficiais." Universidade Federal do CearÃ, 2011. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7099.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>No Brasil, estudos de avaliaÃÃo de micropoluentes emergentes em matrizes ambientais como esgotos sanitÃrios e hospitalares, e corpos de Ãgua, ainda sÃo bastante incipientes, assim como a remoÃÃo desses compostos em EstaÃÃes de Tratamento de Esgotos (ETEs) de baixo custo como lagoas de estabilizaÃÃo, assim como em sistemas de lodos ativados e sistemas anaerÃbio-aerÃbio compactos. O presente trabalho teve como objetivo geral investigar a presenÃa de micropoluentes em matrizes ambientais como esgotos sanitÃrios e hospitalar
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36

Idder, Salima. "État de la contamination des eaux du département de la Dordogne par les résidus de médicaments." Thesis, Bordeaux 1, 2012. http://www.theses.fr/2012BOR14652/document.

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Le début du 21e siècle a vu naître un intérêt croissant pour la problématique des résidus de médicaments dans les milieux aquatiques. L’apparition de nouvelles technologies analytiques permettant la détection et la quantification de molécules à l’état d’ultra-traces a fortement contribué à cette expansion. Ces améliorations technologiques ont permis la recherche et la quantification de nombreux xénobiotiques dans les différents compartiments aquatiques. Depuis une quinzaine d’années, l’attention des équipes de recherche s’est ainsi portée sur les résidus de médicaments à usage humain ou vétéri
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37

Bui, Van Hoi. "Contribution à l’étude de la présence et du devenir des résidus de médicaments dans les compartiments aquatiques." Thesis, Bordeaux 1, 2013. http://www.theses.fr/2013BOR14930/document.

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La présence de résidus de médicaments a été évaluée dans des eaux superficielles et des effluents de huit stations d'épuration (quatre rejetant dans l'estuaire de Seine dans le cadre du projet Medseine financé par le GIP Seine- Aval, quatre dans le cadre du projet Toxstep financé par l'Anses (ex-Afsset). Une centaine de molécules a été systématiquement recherchée dans les deux types d'eaux en appliquant des méthodologies analytiques impliquant une extraction solide liquide suivie une analyse par LC-MS/MS. Un suivi saisonnier des rejets de médicaments a été effectué également. Des résidus de mé
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38

Burešová, Jitka. "Využití separačních metod pro studium vybraných léčiv a pesticidů ve vodách." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2015. http://www.nusl.cz/ntk/nusl-234424.

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This work is focused on the study of penetration of pesticides and pharmaceuticals in the aquatic environment. The aim was to develop and verify the optimal method for long-term monitoring of the occurrence of selected pesticides and pharmaceuticals in surface waters. Two frequently used analgesics ibuprofen and diclofenac, and carbamazepine that is used to treat epilepsy, were chosen from the group of drugs. A group of 41 pesticides were selected for monitoring too. The attention was focused on a group of urea pesticides and phenoxyacetic acids, as well as on selected pesticides falling to th
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39

Idder, Salima. "État de la contamination des eaux du département de la Dordogne par les résidus de médicaments." Electronic Thesis or Diss., Bordeaux 1, 2012. http://www.theses.fr/2012BOR14652.

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Le début du 21e siècle a vu naître un intérêt croissant pour la problématique des résidus de médicaments dans les milieux aquatiques. L’apparition de nouvelles technologies analytiques permettant la détection et la quantification de molécules à l’état d’ultra-traces a fortement contribué à cette expansion. Ces améliorations technologiques ont permis la recherche et la quantification de nombreux xénobiotiques dans les différents compartiments aquatiques. Depuis une quinzaine d’années, l’attention des équipes de recherche s’est ainsi portée sur les résidus de médicaments à usage humain ou vétéri
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40

Vašíčková, Petra. "Stanovení reziduí léčiv pomocí separačních metod." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216632.

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Nonsteroidal anti-inflammatory substances became a very frequently used and constantly evolved group of the drugs, particularly in a human medicine. The risk of their penetration into the environment, especially to the water environment, is rising during the recent years. The diploma thesis is focused on a selection of appropriate separation method and optimization of analytical procedure for the identification and determination of the non-steroidal anti-inflammatory drugs in sewage and surface waters. Salicylic acid, ketoprofen, diclofenac and ibuprofen were chosen from the wide range of NSAI
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Charuaud, Lise. "Résidus de médicaments vétérinaires dans les eaux destinées à la consommation humaine en zone d'élevage intensif : cas de bassins versants bretons." Thesis, Rennes 1, 2018. http://www.theses.fr/2018REN1B066.

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La Directive Cadre sur l’Eau (2000) fait état de la dégradation du bon état chimique des eaux superficielles et des eaux souterraines. Parmi les polluants émergents mis en cause figurent les résidus de médicaments qui représentent une menace diffuse et potentiellement persistante dans les hydro-systèmes. A ce jour, peu d’études se sont intéressées spécifiquement aux résidus médicamenteux vétérinaires (RMV). En France, la Bretagne est une région d'élevage intensif. 75% des eaux destinées à la consommation humaine (EDCH) sont issues d’eau de surface particulièrement vulnérables. Dans ce contexte
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42

Murad, Hassan. "Membranbioreaktorer och deras förmåga att avlägsna prioriterade mikroföroreningar." Thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-366881.

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Spridning av läkemedelsrester och andra prioriterade mikroföroreningar i miljön har uppmärksammats och stor oro väckts kring problematiken. Bland observationer som forskare har noterat till följd av antibiotika, hormoner och läkemedel i vattenmiljöer är bland annat bakteriell resistens, könsbyte och sterilitet hos fisk och groddjur. Persistenta föroreningar som per- och polyfluor alkalysyror (PFAS) bryts inte heller ner i naturen och mikroskräppartiklar kan anrikas i vattendrag och orsaka negativa effekter på vattenlevande organismer. Gemensamt för mikroföroreningar är att dessa förekommer oft
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43

Bui, Van Hoi. "Contribution à l’étude de la présence et du devenir des résidus de médicaments dans les compartiments aquatiques." Electronic Thesis or Diss., Bordeaux 1, 2013. http://www.theses.fr/2013BOR14930.

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La présence de résidus de médicaments a été évaluée dans des eaux superficielles et des effluents de huit stations d'épuration (quatre rejetant dans l'estuaire de Seine dans le cadre du projet Medseine financé par le GIP Seine- Aval, quatre dans le cadre du projet Toxstep financé par l'Anses (ex-Afsset). Une centaine de molécules a été systématiquement recherchée dans les deux types d'eaux en appliquant des méthodologies analytiques impliquant une extraction solide liquide suivie une analyse par LC-MS/MS. Un suivi saisonnier des rejets de médicaments a été effectué également. Des résidus de mé
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44

Lacina, Petr. "Využití plynové chromatografie s hmotnostně spektrometrickou detekcí pro posouzení kontaminace odpadních a povrchových vod rezidui léčiv." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-233363.

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This work is based on the current issue of increasing concentrations of pharmaceutical residues in various components of the environment. These new environmental contaminants continuously enter the environment. The most affected environmental component is the aquatic environment. This study is focused on the development and optimization of reliable analytical method, which can determine selected drugs in the aquatic environment (waste waters and surface waters) qualitatively and quantitatively. The target compounds were selected mainly from the group of non-steroidal anti-inflammatory drugs (N
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45

Lin, Wan-Ching, and 林宛靜. "Fast Analysis of Pharmaceutical Residues in Waters by GC-MS." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/64794107413737999902.

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碩士<br>國立中央大學<br>化學研究所<br>91<br>In contrast to agrochemicals and industrial chemicals, most of pharmaceutical residues are discharged into the environment on a continual basis via domestic/industrial sewage system and wet-weather runoff. These bioactive chemical residues and their metabolites are ubiquitous and persistently occur in surface water as commonly as the widely recognized persistent organic pollutants (POPs). Therefore, it is necessary to develop convenient analytical methods to study how these residues impact the environment. This work presents a modified method to analyze selected
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Almeida, Raquel Sofia David de. "Direct and indirect uptake of pharmaceutical residues in a marine trophic segment." Master's thesis, 2020. http://hdl.handle.net/10451/47977.

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Tese de mestrado em Ciências do Mar, Universidade de Lisboa, Faculdade de Ciências, 2020<br>O valor ecológico e económico dos estuários é inegável, bem como é incontestável as contínuas descargas de águas contaminadas nestas áreas, muitas vezes repletas de resíduos farmacêuticos. Um dos fármacos mais prescritos atualmente é o antidepressivo fluoxetina, e é consequentemente um dos fármacos mais frequentemente detetado em estuários. Por essa razão, adquire um grande potencial para induzir efeitos nefastos em espécies não alvo, interferindo em funções essenciais dos organismos, tais como as funçõ
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Chu, Jhih-Wei, Jin Yin, Daniel I. C. Wang, and Bernhardt L. Trout. "On the Oxidation of Methionine Residues during the Storage of Protein Pharmaceuticals in an Aqueous Formulation." 2003. http://hdl.handle.net/1721.1/3940.

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This study addresses the fundamentals of an important degradation pathway of storing protein pharmaceuticals in an aqueous formulation, oxidation of methionine residues by peroxides. First, a mechanism by which methionine residues are oxidized is identified via ab initio calculations. The major difference of this new mechanism to previous ones is the role of solvent molecules in the oxidation process. Previously proposed mechanisms suggested that solvent molecules facilitate the transfer of hydrogen associated with the oxidation reaction, but the estimated activation energies and pH dependence
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Carvalho, Pedro Neves de. "Implementation of methodologies for removal of veterinary pharmaceuticals residues from WWTPs effluents of the livestock industry." Doctoral thesis, 2012. https://repositorio-aberto.up.pt/handle/10216/65210.

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Carvalho, Pedro Neves de. "Implementation of methodologies for removal of veterinary pharmaceuticals residues from WWTPs effluents of the livestock industry." Tese, 2012. https://repositorio-aberto.up.pt/handle/10216/65210.

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Blaney, Lee Michael. "Oxidation of pharmaceuticals : impacts of natural organic matter and elimination of residual pharmacological activity." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-08-3882.

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Anthropogenically-derived substances, including pharmaceuticals and personal care products, endocrine-disrupting chemicals, and pesticides, are increasingly being detected in drinking water supplies and wastewater effluents. Concerns over the presence of these compounds in water supplies include their ability to impart toxicological activity, their capacity to spread antibiotic resistance, and their potential to affect cell-signaling processes. For these reasons, water treatment processes geared towards removal of these trace organic contaminants are vital. In this work, ozone was used to t
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