Relevant bibliographies by topics / Pharmacological benefits

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pharmacological benefits'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Pharmacological benefits"

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IRKIN, Latife Ceyda, and Özlem YAYINTAS. "Pharmacological Properties and Therapeutic Benefits of Seaweeds A Review." International Journal of Trend in Scientific Research and Development Volume-2, Issue-2 (2018): 1126–31. http://dx.doi.org/10.31142/ijtsrd9567.

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Nizam, Nuder Nower, Sohel Mahmud, Mohammad Kamruzzaman, and Md Kamrul Hasan. "Bakuchiol and its pharmacological benefits." F1000Research 12 (January 9, 2023): 29. http://dx.doi.org/10.12688/f1000research.129072.1.

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Background and aims: Natural compounds extracted from medicinal plants have recently gained attention in therapeutics as they are considered to have lower toxicity and higher tolerability relative to chemically synthesized compounds. Bakuchiol is one such compound; it is a type of meroterpene derived from the leaves and seeds of Psoralea corylifolia plants. Natural sources of bakuchiol have been used in traditional Chinese and Indian medicine for centuries due to its preventive benefits against tumors and inflammation. It plays a strong potential role as an antioxidant with impressive abilitie
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Saraswathi, K., and CH Naga Kavitha. "Spirulina: Pharmacological Activities and Health Benefits." Journal of Young Pharmacists 15, no. 3 (2023): 441–47. http://dx.doi.org/10.5530/jyp.2023.15.59.

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Aboulaghras, Sara, Nargis Sahib, Saad Bakrim, et al. "Health Benefits and Pharmacological Aspects of Chrysoeriol." Pharmaceuticals 15, no. 8 (2022): 973. http://dx.doi.org/10.3390/ph15080973.

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A flavone, chrysoeriol is synthetized in several plant species. It comes from several natural sources, especially medicinal plants. The identification and isolation of this compound has been carried out and verified by several research teams using different spectral methods. It seems that the concentration of this molecule is variable and fluctuating depending on the source, the part extracted, the region, and the methods of extraction and characterization. The aim of this paper is to highlight the in vitro and in vivo pharmacological properties of chrysoeriol and to provide insight into its p
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Bakrim, Saad, Nesrine Benkhaira, Ilhame Bourais, et al. "Health Benefits and Pharmacological Properties of Stigmasterol." Antioxidants 11, no. 10 (2022): 1912. http://dx.doi.org/10.3390/antiox11101912.

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Stigmasterol is an unsaturated phytosterol belonging to the class of tetracyclic triterpenes. It is one of the most common plant sterols, found in a variety of natural sources, including vegetable fats or oils from many plants. Currently, stigmasterol has been examined via in vitro and in vivo assays and molecular docking for its various biological activities on different metabolic disorders. The findings indicate potent pharmacological effects such as anticancer, anti-osteoarthritis, anti-inflammatory, anti-diabetic, immunomodulatory, antiparasitic, antifungal, antibacterial, antioxidant, and
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Bouyahya, Abdelhakim, Hamza Mechchate, Taoufiq Benali, et al. "Health Benefits and Pharmacological Properties of Carvone." Biomolecules 11, no. 12 (2021): 1803. http://dx.doi.org/10.3390/biom11121803.

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Carvone is a monoterpene ketone contained in the essential oils of several aromatic and medicinal plants of the Lamiaceae and Asteraceae families. From aromatic plants, this monoterpene is secreted at different concentrations depending on the species, the parts used, and the extraction methods. Currently, pharmacological investigations showed that carvone exhibits multiple pharmacological properties such as antibacterial, antifungal, antiparasitic, antineuraminidase, antioxidant, anti-inflammatory, and anticancer activities. These studies were carried out in vitro and in vivo and involved a gr
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El Hachlafi, Naoufal, Fatima Lakhdar, Aya Khouchlaa, et al. "Health Benefits and Pharmacological Properties of Hinokitiol." Processes 9, no. 9 (2021): 1680. http://dx.doi.org/10.3390/pr9091680.

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Hinokitiol is a natural bioactive compound found in several aromatic and medicinal plants. It is a terpenoid synthetized and secreted by different species as secondary metabolites. This volatile compound was tested and explored for its different biological properties. In this review, we report the pharmacological properties of hinokitiol by focusing mainly on its anticancer mechanisms. Indeed, it can block cell transformation at different levels by its action on the cell cycle, apoptosis, autophagy via inhibiting gene expression and dysregulating cellular signaling pathways. Moreover, hinokiti
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., Nisha Vats, and Pankaj Taneja . "PHARMACOLOGICAL AND HEALTH BENEFITS OF MEDICINAL PLANTS." International Journal of Engineering Applied Sciences and Technology 4, no. 3 (2019): 195–200. http://dx.doi.org/10.33564/ijeast.2019.v04i03.034.

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Marthandam Asokan, Shibu, Ravichandran Mariappan, Shanmugavadivu Muthusamy, and Bharath Kumar Velmurugan. "Pharmacological benefits of neferine - A comprehensive review." Life Sciences 199 (April 2018): 60–70. http://dx.doi.org/10.1016/j.lfs.2018.02.032.

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Scatena, R., P. Bottoni, A. Pontoglio, and B. Giardina. "Pharmacological Modulation of Nitric Oxide Release: New Pharmacological Perspectives, Potential Benefits and Risks." Current Medicinal Chemistry 17, no. 1 (2010): 61–73. http://dx.doi.org/10.2174/092986710789957841.

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Dissertations / Theses on the topic "Pharmacological benefits"

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Vella, Sandro. "Pharmacological modulation of insulin resistance : benefits and harms." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/4428eca5-5018-4816-95d0-30c0a3043409.

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Aims: Thiazolidinediones have been advocated as second or third line insulin sensitizing agents in the management of type 2 diabetes (T2DM). Their widespread use has been hampered by concerns about their cardiovascular safety, including fluid retention. Metformin is established as first-line glucose-lowering pharmacotherapy in T2DM. It has also been suggested that it may have benefits in alleviating insulin resistance in type 1 diabetes (T1DM). This thesis examined: (i) cardiovascular, renal and metabolic differences between individuals with T2DM ‘tolerant’ or ‘intolerant’ of TZDs; (ii) risk f
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Botha, Jan. "The development of a device for the investigation of dorsiflexion range of the ankle with a capacity to measure pathology, recovery and pharmacological benefit." Thesis, Stellenbosch : University of Stellenbosch, 2005. http://hdl.handle.net/10019.1/2086.

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Thesis (MScEng (Mechanical and Mechatronic Engineering))--University of Stellenbosch, 2005.<br>Various ways exist whereby balance abilities of the individual can be assessed. However, most of these are subjective methods. This thesis strives to demonstrate the effectiveness of a new device, the Dorsiflexometer that can be used to objectively assess one’s balance abilities. The Dorsiflexometer was constructed and mathematically modelled using appropriate simplifying assumptions. After its construction, the Dorsiflexometer was tested using two experimental set-ups to obtain raw data. Both
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Books on the topic "Pharmacological benefits"

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Radhakrishnan, Narayanaswamy, and Srinivasan Vasantha. Pharmacological Benefits of Natural Agents. IGI Global, 2023.

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Radhakrishnan, Narayanaswamy, and Srinivasan Vasantha. Pharmacological Benefits of Natural Agents. IGI Global, 2023.

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Radhakrishnan, Narayanaswamy, and Srinivasan Vasantha. Pharmacological Benefits of Natural Agents. IGI Global, 2023.

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Radhakrishnan, Narayanaswamy, and Srinivasan Vasantha. Pharmacological Benefits of Natural Agents. IGI Global, 2023.

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Wilkinson, David. Pharmacological treatment of Alzheimer’s disease. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199569854.003.0007.

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• Pharmacotherapy of Alzheimer’s disease (AD) has progressed in the last 10 years with the emergence of rational treatments aimed at neuro-transmitter replacement• All the compounds improve attention and alertness and have global benefits for patient and carer not always reflected in improvements in cognitive scores...
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Dougherty, Darin D., Scott L. Rauch, and Michael A. Jenike. Pharmacological Treatments for Obsessive Compulsive Disorder. Edited by Gail Steketee. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195376210.013.0061.

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Progress in treating OCD has accelerated in recent years. Effective first-line treatments include behavior therapy and medications, with overwhelming evidence supporting the efficacy of serotonergic reuptake inhibitors (SRIs). Second-line medication treatments for OCD include augmentation of SRIs with neuroleptics, clonazepam, or buspirone, with limited support for other strategies at present. Alternative monotherapies (e.g., buspirone, clonazepam, phenelzine) have more limited supporting data and require further study. Behavior therapy, and perhaps cognitive therapy, is as effective as medica
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Siebert, Stefan, Sengupta Raj, and Alexander Tsoukas. Non-pharmacological treatment of axial spondyloarthritis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198755296.003.0014.

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While drugs play a key role in reducing disease activity, non-pharmacological therapies are crucial in maintaining function, flexibility, and quality of life. Therefore, non-pharmacological therapy remains a key component in the optimal management of axial spondyloarthritis (axSpA), even in the era of biologics. Regular physical therapy allows patients to capitalize on the benefits of drug therapy and maintain optimal functional ability. Self-management and education strategies, supported by patient-support groups, facilitate independence and quality of life in chronic diseases. A proportion o
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Gad, Heba, Daniel Bateman, and Paul E. Holtzheimer. Neurostimulation Therapies, Side Effects, Risks, and Benefits. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199374656.003.0016.

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Neurostimulation therapies are an alternative for non-responders to pharmacological or psychotherapy management, as well as when first-line treatments are contraindicated for treatment of neuropsychiatric disorders in the elderly. Brain stimulation treatments for neuropsychiatric disorders include the following FDA approved treatments for major depressive disorder: electroconvulsive therapy (ECT), which remains one of the most effective therapies for several neuropsychiatric disorders; repetitive transcranial magnetic stimulation (rTMS); and vagus nerve stimulation (VNS). Deep brain stimulatio
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Grant, Jon E., Brian L. Odlaug, and Marc N. Potenza. Treatments for Gambling Disorder and Impulse Control Disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0025.

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Specific behavioral (e.g., cognitive-behavioral therapy [CBT]) and pharmacological (e.g., naltrexone, nalmefene, lithium) treatments significantly reduce the symptoms of pathological gambling (now termed gambling disorder in DSM-5) in the short term compared with waitlist or placebo. The long-term benefits of pharmacological treatment for gambling disorder have not been adequately tested. Although several studies suggest that CBT is effective for trichotillomania, only two pharmacological treatment studies in adults (N-acetylcysteine, olanzapine) for this disorder have shown promise. Studies o
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Kass, Erica, Jonathan E. Posner, and Laurence L. Greenhill. Pharmacological Treatments for Attention-Deficit/Hyperactivity Disorder and Disruptive Behavior Disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0004.

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More than 225 placebo-controlled type 1 investigations demonstrate that psychostimulants are highly effective in reducing core symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adults. In contrast, there are limited type I studies demonstrating that psychopharmacological management with U.S. Food &amp; Drug Administration-approved agents for ADHD (stimulants and nonstimulants), atypical antipsychotics, and mood stabilizers decrease the defiant and aggressive behavior characteristic of disruptive behavior disorders. Stimulant treatment evidence has been supplemented by
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Book chapters on the topic "Pharmacological benefits"

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Ninot, Gregory. "The Benefits of Non-pharmacological Interventions." In Non-Pharmacological Interventions. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-60971-9_4.

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Székely, Andrea, Daniel Lex, and Béla Merkely. "Aprotinin: Pharmacological Benefits and Safety." In Reducing Mortality in the Perioperative Period. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-46696-5_13.

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Saxena, Richa, Abhirup Mitra, Soniya Joshi, et al. "Potential Pharmacological Health Benefits of Flavonoids." In The Flavonoids. Apple Academic Press, 2023. http://dx.doi.org/10.1201/9781003399964-9.

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Székely, Andrea, Daniel J. Lex, and Béla Merkely. "Aprotinin: Pharmacological Benefits and Safety Concerns." In Reducing Mortality in the Perioperative Period. Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-02186-7_16.

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Füller, A., V. Schumann, and U. Laaser. "Attitude and Behaviour of Stuttgart’s Primary Care Physicians with Regard to the Pharmacological and Non-Pharmacological Treatment of Mild Hypertension." In Costs and Benefits in Health Care and Prevention. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75781-5_6.

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Goyal, Manoj. "Jujubes and Health Benefits: Ethnomedicinal Uses and Pharmacological Activity." In Chinese Dates. CRC Press, 2016. http://dx.doi.org/10.4324/9780429160509-10.

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Andersen, Teis. "Potential Side Costs and Side Benefits of Pharmacological Treatment of Obesity." In Obesity Treatment. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1901-0_21.

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Guzelmeric, Etil. "The “Golden Spice” Curcuma Longa L. and Curcuminoids." In Medicinal Spices. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359340.2.

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The vibrant, yellow to orange-colored dried rhizomes of Curcuma longa L. (turmeric) have been used for centuries as a spice, especially in Chinese and Indian cuisines. This powder is regarded as “Golden spice” due to its wide range of health benefits. Experimental and clinical studies have revealed that the compounds found in rhizomes of turmeric, especially curcuminoids, are mainly responsible for its pharmacological activities such as antioxidant, immunomodulatory, anti-inflammatory, hepatoprotective, and anticancer.
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Singh, Pushpendra, Prem P. Kushwaha, and Shashank Kumar. "Health Benefits and Pharmacological Molecular Properties of Isoflavandiol (Equol): In-silico and in-vitro Updates." In Phytochemistry: An in-silico and in-vitro Update. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6920-9_9.

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Nelli, Giribabu, and Naguib Salleh. "Natural Products as Alternative Treatments for Bone Disorders." In Pharmacological Benefits of Natural Agents. IGI Global, 2023. http://dx.doi.org/10.4018/978-1-6684-6737-4.ch014.

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Bone is an active and dynamic organ that is well-differentiated and originated from mesenchymal cells. Bone goes through constant remodeling during its lifetime. Most bone disorders result in loss of bone mass and microarchitectural deterioration, which leads to more osteoclast-mediated bone resorption than osteoblast-mediated bone formation. Natural products have been used to treat bone disorders since ancient times and have gained favor in recent years. Natural products have grown in popularity worldwide over the last few decades, according to the World Health Organization (WHO), and are now
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Conference papers on the topic "Pharmacological benefits"

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Rana, Ruhi, Gagandeep Kaur, Sukhanpreet Kaur, et al. "Multiple pharmacological benefits of sildenafil." In 14TH INTERNATIONAL CONFERENCE ON MATERIALS PROCESSING AND CHARACTERIZATION 2023. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0192552.

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Gomes, Monique, Amanda Rodrigues, Indianara Rosa, and Daniel Perez Sampaio. "MUSIC THERAPY IN DEMENTIA PATIENTS: WHAT ARE THE BENEFITS?" In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda078.

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Background: Dementia is an acquired status, characterized by a decline in at least two cognitive domains, severe enough to affect social or occupational functioning. The standard pharmacological treatment for dementia has limited efficacy, especially in non-cognitive outcomes. Music therapy (MT) is being studied as anon-pharmacological therapy for Dementia, due to its stimulating effects. Objective: Understand the main benefits of MT in dementia patients, through a systematic review. Methods: A literature research was carried out using the databases: PubMed and Scielo. The period of publicatio
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Guimarães, Matheus Procópio, Renata de Aquino Ferreira, Pedro Henrick Guimarães Carvalho, et al. "Benefits of yoga on quality of life of people with remittingrecurring multiple sclerosis." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.652.

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Introduction: Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous system. MS can be accompanied by physical, psychological, and/or cognitive symptoms, which can limit the quality of life of patients. Therefore, in addition to pharmacological treatment, it is required the participation of integrative and complementary therapies such as Yoga. Objectives: To analyze the benefits of Yoga on the quality of life of people with relapsing-remitting MS (RRMS). Methods: This is an observational, exploratory, descriptive, cross-sectional, and qualitative field resear
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de Lacerda, Dhiego Alves, Pedro Fechine Honorato, Renata Braga Vale, et al. "Role of Angiotensin Converting Enzyme Inhibitors (ACEIs) in Heart Failure: Mechanism of Action and Benefits of ACEIs." In III Seven International Medical and Nursing Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iiicongressmedicalnursing-036.

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INTRODUCTION: Heart failure is a chronic condition characterized by the inability of the heart to pump blood effectively. Angiotensin-converting enzyme inhibitors (ACEIs) are essential in the treatment of this condition, due to their vasodilatory, antihypertensive and cardioprotective effects. OBJECTIVE: This summary explores the mechanism of action of ACEIs and the benefits associated with their use in the management of heart failure, based on information from renowned academic sources. METHODOLOGY: A literature review was performed using works such as: Goodman and Gilman's The Pharmacologica
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Levi, Russell, Saad Ahmed, and Zachary Harris. "Can Nutritional Supplements Benefit Patients Receiving Treatment for Neurodegenerative Disorders?" In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.53_2024.

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As the prevalence of neurocognitive disorders rises globally, developing new methodologies of prevention and treatment is crucial. This literature review examines the efficacy of adding nutritional supplements, specifically nootropics, with traditional pharmacological regimens on various neurocognitive and neurodegenerative disorders. Primary, peer-reviewed research, including both human and animal studies, was assesed to determine if there was a benefifical, minimal, or detrimental effect on symptom progression. The inclusion criteria focused on studies that evaluated the reduction in disease
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Madić, Višnja, Aleksandra Petrović, and Perica Vasiljević. "ETHNOPHARMACOLOGY OF DIABETES: FROM TRADITIONAL RECIPES TO MODERN MEDICINE." In 58. Kongres Antropološkog društva Srbije. Antropološko društvo Srbije, 2025. https://doi.org/10.46793/ads25.34m.

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Diabetes is one of the most prevalent chronic diseases of the 21st century. Current pharmacological interventions used in the management of this condition regulate hyperglycemia; however, they do not fully prevent the onset or progression of its secondary complications, including diabetic nephropathy, hepatic dysfunction, osteoporosis, neuropathy, retinopathy, cardiovascular diseases, increased risk of dementia, etc. Consequently, a growing number of individuals with diabetes, in addition to conventional pharmacotherapy, are incorporating herbal alternatives derived from traditional medicine,
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ELObeid, Tahra, Susanna Phoboo, and Kalidas Shetty. "Anti-diabetic and Anti-hypertensive Potential of Indigenous Edible plants of Qatar." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0142.

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Aizoon Canariense, Cynomorium Coccineum, Glossonema Edule, and Malva Parviflora, edible desert plants from Qatar, were selected to determine levels of phenolic bioactives and potential health benefits for managing early stages of type 2 diabetes and hypertension. Aqueous extracts of C. Cocineum, contained soluble phenolics and had relatively high levels of antioxidant activity associated with α-glucosidase, α-amylase, and angiotensin- converting enzyme (ACE). G. Edule and M. Parviflora had moderate levels of anti-oxidant potential, soluble phenolics, and ACE inhibitory activity. The medicinal
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Oliveira, Vívian Maria Gomes de, Cíntia Gonçalves Nogueira, Gabriela Ferreira Paticcié, et al. "Effects of Aerobic Exercise on Cognition and Activities of Daily Living in Alzheimer’s Disease: A Systematic Review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.543.

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Background: Alzheimer’s disease (AD) represents one of the main causes of cognitive and functional decline in the world. Concomitant with pharmacological treatment, the practice of aerobic exercises (AE) can help in the symptomatic control of the disease. Objectives: To evaluate the effects of AE on activities of daily living and cognition in patients with AD. Methods: A systematic review was undertaken. EMBASE, Pubmed and BVS databases were searched using the terms “Alzheimer disease”, “Alzheimer syndrome” and “Alzheimer dementia”; “aerobic” and “exercise”. The inclusion criteria were: random
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Crawford, Russell. "Learning Gain using a game improve pharmacology knowledge in two transnational HE institutes." In Fifth International Conference on Higher Education Advances. Universitat Politècnica València, 2019. http://dx.doi.org/10.4995/head19.2019.9412.

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Gamification in higher education has been shown to provide a diverse range of learning opportunities for higher education practitioners as well as students. Building on our research exploring the benefits of using a card-based, role-playing team game called “BrainceptTM” to aid pharmacology learning for medical students, we now test the reproducibility of our novel finding that this game leads to appreciable and sustained learning gains in medical students from two different higher education institutes. Here we present student feedback, thematic analysis and quantitative pre-and post-test data
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Razoni, Fabrício, Letícia Morais, Maria Gabriela Leal, et al. "USE OF METHYLPHENIDATE IN COGNITIVE ENHANCEMENT OF HEALTHY INDIVIDUALS: A SYSTEMATIC REVIEW." In I Congresso Internacional Multidisciplinar de Ciências da Saúde - I CIMS. New Science Publishers, 2024. http://dx.doi.org/10.56238/i-cims-011.

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Introduction: The increase in non-medical use of methylphenidate by healthy individuals raises ethical, safety and efficacy issues. Understanding these issues is crucial given the social pressures for performance and the potential impact on long-term mental health. Objective: To describe the risks, potential benefits and ethical challenges of using methylphenidate for cognitive enhancement in healthy individuals. To evaluate the effects on declarative memory, short-term and long-term memory, and assess the pharmacological risks. Methods: A systematic review of the literature was conducted incl
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Reports on the topic "Pharmacological benefits"

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Basu, Sayani. Hyperbaric Oxygen Therapy: A Breakthrough in Healthcare. Science Repository Oü, 2020. http://dx.doi.org/10.31487/sr.blog.22.

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The physiological and pharmacological benefits and high therapeutic response of hyperbaric oxygen therapy indicates that hyperbaric oxygen therapy offers promise in the treatment of a wide range of medical conditions.
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Dy, Sydney M., Arjun Gupta, Julie M. Waldfogel, et al. Interventions for Breathlessness in Patients With Advanced Cancer. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer232.

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Objectives. To assess benefits and harms of nonpharmacological and pharmacological interventions for breathlessness in adults with advanced cancer. Data sources. We searched PubMed®, Embase®, CINAHL®, ISI Web of Science, and the Cochrane Central Register of Controlled Trials through early May 2020. Review methods. We included randomized controlled trials (RCTs) and observational studies with a comparison group evaluating benefits and/or harms, and cohort studies reporting harms. Two reviewers independently screened search results, serially abstracted data, assessed risk of bias, and graded str
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Kennedy, Sara M., and Rania Ali. Baclofen for Alcohol Use Disorder: A Cochrane Review Summary With Commentary. RTI Press, 2025. https://doi.org/10.3768/rtipress.2025.rb.0040.2502.

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This brief summarizes the Cochrane Review, “Baclofen for Alcohol Use Disorder,” by R. Agabio, R. Saulle, S. Rösner, and S. Minozzi (https://doi.org/10.1002/14651858.CD012557.pub3). The Cochrane Review examines evidence for benefits and harms of baclofen on achieving and maintaining abstinence or reducing alcohol consumption in people with alcohol use disorder (AUD) compared to placebo, no treatment, or any other pharmacological relapse prevention treatment. Review authors conclude that baclofen likely reduces the risk of relapse to any drinking and increases the percentage of abstinent days, m
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Selph, Shelley S., Andrea C. Skelly, Tracy Dana, et al. Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents: A Systematic Review. Agency for Healthcare Research and Quality, 2025. https://doi.org/10.23970/ahrqepcsrdisruptive.

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Objectives. To determine the most effective treatments for clinically significant disruptive behaviors in children and adolescents. Data sources. Ovid® MEDLINE®, the Cochrane Library, PsycINFO®, and Embase® databases were searched from 2014 to July 22, 2024. Additionally, we reviewed all studies included in the prior 2015 Agency for Healthcare Research and Quality review. Review methods. We dual reviewed abstracts and full-text articles; data extraction was checked by a second reviewer; risk of bias and strength of evidence were assessed by two reviewers; and disagreements were resolved by con
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Viswanathan, Meera, Jennifer Cook Middleton, Alison Stuebe, et al. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer236.

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Background. Untreated maternal mental health disorders can have devastating sequelae for the mother and child. For women who are currently or planning to become pregnant or are breastfeeding, a critical question is whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms for mother and child. Methods. We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared with placebo, no treatment, or other pharmacologic interventions for pregnant and postpartum women with mental health disorders. We searched fo
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Steele, Dale W., Gaelen P. Adam, Ian J. Saldanha, et al. Management of Postpartum Hypertensive Disorders of Pregnancy. Agency for Healthcare Research and Quality (AHRQ), 2023. http://dx.doi.org/10.23970/ahrqepccer263.

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Background. Hypertensive disorders of pregnancy (HDP) are increasingly common and have important implications for maternal health, healthcare utilization, and health disparities. There is limited evidence to support best management of postpartum individuals with HDP, including home blood pressure (BP) monitoring (HBPM) and choice of antihypertensive agents. For patients experiencing preeclampsia with severe features, there is robust evidence supporting delivery of the infant and treatment with magnesium sulfate (MgSO4). However, MgSO4 may cause unpleasant side effects and, less commonly, toxic
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Chou, Roger, Jesse Wagner, Azrah Y. Ahmed, et al. Treatments for Acute Pain: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer240.

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Objectives. To evaluate the effectiveness and comparative effectiveness of opioid, nonopioid pharmacologic, and nonpharmacologic therapy in patients with specific types of acute pain, including effects on pain, function, quality of life, adverse events, and long-term use of opioids. Data sources. Electronic databases (Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews) to August 2020, reference lists, and a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomiz
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