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Journal articles on the topic 'Pharmacological Investigations'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

RENUKA, JAIN, and ARORA REKHA. "Phytochemical and Pharmacological Investigation of Heliotropium ellipticum Ledeb." Journal of Indian Chemical Society Vol. 74, May 1997 (1997): 430–31. https://doi.org/10.5281/zenodo.5909098.

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Department of Chemistry, University of Rajasthan. Jaipur-302 004 <em>Manuscript received 31 October 1995. revised 18 January 1996, accepted 19 January 1996</em> Phytochemical and Pharmacological Investigation of <em>Heliotropium ellipticum</em> Ledeb.

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2

Zinovieva, M. L., N. V. Kurdil, P. G. Zhminko, M. G. Prodanchuk, O. P. Kravchuk, and M. V. Velychko. "Pharmacological therapeutic appliance for acute poisoning by organophosphorous compounds of anticholinesterase action (review of literature)." Ukrainian Journal of Modern Toxicological Aspects 94, no. 1 (2023): 42–54. http://dx.doi.org/10.33273/2663-4570-2023-94-1-42-54.

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The current standards of treatment the acute OPC poisoning with anticholinesterase action remain insufficient, despite the significant number of researches in this area conducted in the world. One of the ways to solve this problem is to use a wider range of pathogenetically determined pharmacologic agents. The Aim of the Research. To observe and summarize the published results of investigation the pharmacological therapeutic appliance for acute OPC poisoning at the stages of preclinical and early clinical evaluation. Methods. System content analysis of literature data using the PubMed and Goog

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3

Kuhnt, M., A. Pröbstle, R. Bauer, and M. Heinrich. "Biological and Pharmacological Investigations ofHyptis verticillata." Planta Medica 59, S 1 (1993): A665. http://dx.doi.org/10.1055/s-2006-959935.

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Bauer, R., K. Redl, and B. Davis. "Phytochemical and Pharmacological Investigations ofBidens campylotheca." Planta Medica 57, S 2 (1991): A68. http://dx.doi.org/10.1055/s-2006-960333.

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5

Sendl, A., G. Elbl, B. Steinke, K. Redl, W. Breu, and H. Wagner. "Comparative Pharmacological Investigations ofAllium ursinumandAllium sativum." Planta Medica 58, no. 01 (1992): 1–7. http://dx.doi.org/10.1055/s-2006-961378.

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6

Varpe, Bhushan D. "Isatin Hybrids and Their Pharmacological Investigations." Mini-Reviews in Medicinal Chemistry 21, no. 10 (2021): 1182–225. http://dx.doi.org/10.2174/18755607mteydmjykw.

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7

Nourmohammadi, Jalal, Mohsen Akhondi, Fereshte Rajabiniat, Zahra S. H. Vaeaz, Zahra Nourmohammadi, and Mahdieh H. Moghadam. "Pharmacological evaluation of glomerulonephritis in Covid-19 patients." Romanian Journal of Military Medicine 125, no. 4 (2022): 630–35. http://dx.doi.org/10.55453/rjmm.2022.125.4.14.

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"Acute kidney injury (AKI) and glomerulonephritis can be complications in COVID-19 patients, which is announced with widely incidence rates in different investigations and is determined to have a major effect on the prognosis of the disease. There are considerable variations in AKI and glomerulonephritis rates between other countries. The rate is generally lower than in Western Europe and the United States in China. Heterogeneity in different racial and ethnic lines can be a potential explanation. This investigation systematically reviews the scientific resources regarding AKI and glomerulonep

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Kosic-Spasojevic, Ljubica, and Dragisa Trailovic. "Possibilities of applying pharmacological stress testing in assessment of heart functional capacity in dogs." Veterinarski glasnik 64, no. 3-4 (2010): 287–96. http://dx.doi.org/10.2298/vetgl1004287k.

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Systolic and diastolic heart functions, evaluated using echocardiography, do not reflect the functional capacity of the patient and they cannot explain the occurrence of symptoms during a certain degree of activity. Evaluation of the functional capacity is an integral part of cardiological examinations in human medicine. Functional examinations of the heart can be carried out using the body burden test or pharmacologically. Investigations carried out so far into canine cardiology have not contributed to the clinical implementation of functional heart examinations in dogs. Pharmacological stres

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Zhou, Zehua, Rui An, Lisha You, Kun Liang, and Xinhong Wang. "Banxia Xiexin decoction: A review on phytochemical, pharmacological, clinical and pharmacokinetic investigations." Medicine 102, no. 35 (2023): e34891. http://dx.doi.org/10.1097/md.0000000000034891.

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Banxia Xiexin decoction (BXD), a famous traditional Chinese prescription constituted by Pinelliae Rhizoma, Zingiberis Rhizoma, Scutellariae Radix, Coptidis Rhizoma, Ginseng Radix et Rhizoma, Jujubae Fructus and Glycyrrhizae Radix et Rhizoma Praeparata Cum Mell, has notable characteristics of acrid-opening, bitter down-bearing and sweet-tonification, interfering with tumors, gastrointestinal diseases, central nervous system diseases and much more. Based on the wide clinical applications, current investigations of BXD focused on several aspects: chemical analysis to explore the underlying substr

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10

Little, H. J., A. Clark, and W. P. Watson. "Investigations into pharmacological antagonism of general anaesthesia." British Journal of Pharmacology 129, no. 8 (2000): 1755–63. http://dx.doi.org/10.1038/sj.bjp.0703262.

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11

Virtbauer, Judith, Liselotte Krenn, Hanspeter Kählig, Antje Hüfner, Oliver Donath, and Brigitte Marian. "Chemical and Pharmacological Investigations of Metaxya rostrata." Zeitschrift für Naturforschung C 63, no. 7-8 (2008): 469–75. http://dx.doi.org/10.1515/znc-2008-7-801.

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In a bioassay-guided approach the chemical composition of rhizomes of Metaxya rostrata (Kunth C. Presl) was studied for the first time. Investigations of the cytotoxicity of extracts and fractions on SW480 colorectal carcinoma cells resulted in the isolation of two polyphenols D cinnamtannin B-1 and aesculitannin B. The structures of the compounds were elucidated by different NMR experiments. Additionally, sugars, common sterols, such as sitosterol, stigmasterol and campesterol, as well as chlorogenic acid and caffeic acid were identified in Metaxya rostrata.

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12

Myers, J., and V. F. Froelicher. "Optimizing the exercise test for pharmacological investigations." Circulation 82, no. 5 (1990): 1839–46. http://dx.doi.org/10.1161/01.cir.82.5.1839.

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13

Mundt, Sabine, Susann Kreitlow, Andrea Nowotny, and Uta Effmert. "Biochemical and pharmacological investigations of selected cyanobacteria." International Journal of Hygiene and Environmental Health 203, no. 4 (2001): 327–34. http://dx.doi.org/10.1078/1438-4639-00045.

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14

Tsvetkova, Dobrina, Nikolai Danchev, Irina Nikolova, and Danka Obreshkova. "Pharmacological investigations of new galantamine peptide esters." Biotechnology & Biotechnological Equipment 28, no. 1 (2014): 160–63. http://dx.doi.org/10.1080/13102818.2014.901685.

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15

Amin, Adnan, Emmy Tuenter, Vassiliki Exarchou, et al. "Phytochemical and Pharmacological Investigations onNymphoides indicaLeaf Extracts." Phytotherapy Research 30, no. 10 (2016): 1624–33. http://dx.doi.org/10.1002/ptr.5663.

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16

Jabbar, Ahmed Aj, Fuad O. Abdullah, Abdullah Othman Hassan, et al. "Ethnobotanical, Phytochemistry, and Pharmacological Activity of Onosma (Boraginaceae): An Updated Review." Molecules 27, no. 24 (2022): 8687. http://dx.doi.org/10.3390/molecules27248687.

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The genus Onosma belongs to the Boraginaceae family and contains over 230 species. The present review sheds light on the ethnopharmacology, phytoconstituents, bioactivity, and toxicology of the Onosma species from previous investigations. Furthermore, the paper also highlights the unresolved issues for the future investigations. The review included previous studies of the genus Onosma available from Google Scholar and Baidu Scholar, Science Direct, SciFinder, Wiley Online Library, and Web of Science. Until now, more than 200 chemical compounds have been detected from the genus Onosma, includin

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17

Ahmad, Bashir, Qasim Jan ., Shumaila Bashir ., Muhammad Nisar ., Farzana Shaheen ., and Manzoor Ahmad . "Pharmacological and Biological Investigations of Chenopodium murale Linn." Asian Journal of Plant Sciences 2, no. 15 (2003): 1107–11. http://dx.doi.org/10.3923/ajps.2003.1107.1111.

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Bulbul, Israt Jahan, Mohammad Rashedul Haque, and Mohammad Abdur Rashid. "Pharmacological investigations of Litsea lancifolia (Roxb.) Hook. F." Bangladesh Journal of Botany 49, no. 1 (2020): 179–83. http://dx.doi.org/10.3329/bjb.v49i1.49128.

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The petroleum ether, chloroform and ethyl acetate soluble fractions of methanolic extract of Litsea lancifolia Roxb. leaves were subjected to different pharmacological screenings to explore its potential as anti-oxidant, antimicrobial, peripheral analgesic, hypoglycemic and CNS depressing agent. The ethyl acetate soluble fraction showed highest total phenolic content and free radical scavenging activity compared to the standard, acetyl salicylic acid. Potential antimicrobial activity was shown against P. aeruginosa (23.50 mm), E. coli (22.33 mm), B. cereus (18 mm) and S. paratyphi (18 mm). The

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19

REVERS, F. E. "Clinical and Pharmacological Investigations on Extract of Licorice." Acta Medica Scandinavica 154, S312 (2009): 749–51. http://dx.doi.org/10.1111/j.0954-6820.1956.tb17084.x.

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20

Simões, Claudia Maria Olivera, Eloir Paulo Schenkel, Luis Bauer, and Augusto Langeloh. "Pharmacological investigations on Achyrocline satureioides (Lam.) DC., compositae." Journal of Ethnopharmacology 22, no. 3 (1988): 281–93. http://dx.doi.org/10.1016/0378-8741(88)90239-5.

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21

Kuroshima, Kätia N., Fátima de Campos, Márcia M. de Souza, Rosendo A. Yunes, Franco Delle Monache, and Valdir Cechinel Filho. "Phytochemical and Pharmacological Investigations of Virola oleifera Leaves." Zeitschrift für Naturforschung C 56, no. 9-10 (2001): 703–6. http://dx.doi.org/10.1515/znc-2001-9-1006.

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Abstract A methanolic extract and two fractions (n-hexane and ethyl acetate) from Virola oleifera leaves and some compounds (one lignan and two flavonoids) were investigated to verify the analgesic activity by using the writhing test in mice. The crude methanolic extract showed a moderate analgesic effect (about 40% of inhibition in this test at 10 mg/kg), whereas n-hexane and ethyl acetate fractions caused inhibition of 51.3 ± 5.9% and 50.5 ± 6.3% , respectively. Oleiferin-C (1), a lignan isolated from the n-hexane fraction, showed an interesting analgesic potential in this model when compare

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22

CAMMILLI, LEONARDO, ALESSANDRO MUGELLI, GINO GRASSI, et al. "Implantable Pharmacological Defibrillator (AIPhD): Preliminary Investigations in Animals." Pacing and Clinical Electrophysiology 14, no. 2 (1991): 381–86. http://dx.doi.org/10.1111/j.1540-8159.1991.tb05126.x.

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23

Trendelenburg, Paul. "Physiological and pharmacological investigations of small intestinal peristalsis." Naunyn-Schmiedeberg's Archives of Pharmacology 373, no. 2 (2006): 101–33. http://dx.doi.org/10.1007/s00210-006-0052-7.

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24

Tahseen, Mohd Adil, Aakash Bhatnagar, and Ashish Bhatnagar. "Phytochemical and pharmacological investigations of Graptophyllum pictum leaves." Journal of Pharmacognosy and Phytochemistry 12, no. 6 (2023): 252–66. http://dx.doi.org/10.22271/phyto.2023.v12.i6c.14791.

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25

Arawwawala, L. D. A. M., M. I. Thabrew, and L. S. R. Arambewela. "Trichosanthes cucumerina Linn.: Investigations of some Selected Pharmacological Activities of Ethanolic Extract." Pharmacologia 4, no. 8 (2013): 493–97. http://dx.doi.org/10.5567/pharmacologia.2013.493.497.

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26

Bouyahya, Abdelhakim, Aicha El Allam, Ikrame Zeouk, et al. "Pharmacological Effects of Grifolin: Focusing on Anticancer Mechanisms." Molecules 27, no. 1 (2022): 284. http://dx.doi.org/10.3390/molecules27010284.

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Grifolin is a volatile compound contained in essential oils of several medicinal plants. Several studies show that this substance has been the subject of numerous pharmacological investigations, which have yielded interesting results. Grifolin demonstrated beneficial effects for health via its multiple pharmacological activities. It has anti-microbial properties against bacteria, fungi, and parasites. In addition, grifolin exhibited remarkable anti-cancer effects on different human cancer cells. The anticancer action of this molecule is related to its ability to act at cellular and molecular l

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27

Bouyahya, Abdelhakim, Hamza Mechchate, Taoufiq Benali, et al. "Health Benefits and Pharmacological Properties of Carvone." Biomolecules 11, no. 12 (2021): 1803. http://dx.doi.org/10.3390/biom11121803.

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Carvone is a monoterpene ketone contained in the essential oils of several aromatic and medicinal plants of the Lamiaceae and Asteraceae families. From aromatic plants, this monoterpene is secreted at different concentrations depending on the species, the parts used, and the extraction methods. Currently, pharmacological investigations showed that carvone exhibits multiple pharmacological properties such as antibacterial, antifungal, antiparasitic, antineuraminidase, antioxidant, anti-inflammatory, and anticancer activities. These studies were carried out in vitro and in vivo and involved a gr

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28

Sasi, Sajeesha, Nishat Anjum, and Y. C. Tripathi. "ETHNOMEDICINAL, PHYTOCHEMICAL AND PHARMACOLOGICAL ASPECTS OF FLACOURTIA JANGOMAS: A REVIEW." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 3 (2018): 9. http://dx.doi.org/10.22159/ijpps.2018v10i3.23998.

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Flacourtia jangomas (Lour.) Raeusch., a small tree of Willow family distributed throughout tropical regions of East Africa and Asia is well-known for its culinary and medicinal uses. The plant has received increasing interest due to its limonoid constituents. Phytochemical studies have led to the isolation and characterization of an array of bioactive compounds and pharmacological investigations have validated the traditional uses of the species as well as discovered some new bioefficacies. The aim of the review is to present an updated and comprehensive overview of traditional uses, ethnomedi

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29

Zeenath Khan, M. Madhavi Latha, K. Narendra, G. Sneha latha, K. Babu, and K. Mallikarjuna. "Pharmacological evaluation of rice varieties, Hassawi and Njavara." International Journal of Science and Research Archive 13, no. 2 (2024): 959–69. http://dx.doi.org/10.30574/ijsra.2024.13.2.2110.

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Hasswai and Njavara are two notable international and Indian red rice cultivars that provide a variety of nutrients and phytochemicals. An effort was made to investigate the pharmacological properties of these rice types. In conclusion, both types of rice exhibit lipid peroxidation, acetylcholinesterase, thrombolytic, anti-arthritic, antioxidant, and anti-inflammatory properties. Methanol extracts showed increased acetylcholinesterase, thrombolytic, and antioxidant activity in the current investigation. On the other hand, aqueous extracts have stronger anti-inflammatory, anti-arthritic, lipid

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30

Veeranjaneyulu, A., SL Bodhankar, SK Arora, and DK Arulmozhi. "Pharmacological investigations ofSapindus trifoliatusin variousin vitroandin vivomodels of inflammation." Indian Journal of Pharmacology 37, no. 2 (2005): 96. http://dx.doi.org/10.4103/0253-7613.15109.

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31

Islam, Mehedi, Md Al Amin Sikder, Mohammad A. Rashid, and Md Khalid Hossain. "Phyto-pharmacological Investigations of Leaves of Cissus trifoliata (L.)." Dhaka University Journal of Pharmaceutical Sciences 21, no. 1 (2022): 69–75. http://dx.doi.org/10.3329/dujps.v21i1.60398.

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Repeated chromatographic separation and purification of dichloromethane soluble partitionate of methanol extract of leaves of Cissus trifoliata (L.) yielded a total of four compounds, namely β-sitosterol (1), β- sitostenone (2), epifriedelanol (3) and friedelin (4). The structures of the isolated chemical compounds were established by high field nuclear magnetic resonance (NMR) analyses, comparison with previously published data and co-TLC with authentic samples, whenever possible. Compounds 1-4 appeared to be the first time they were identified in this plant species. The methanol extract of C

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32

Rozza, A. L., C. A. Hiruma-Lima, A. Tanimoto, and C. H. Pellizzon. "Morphologic and Pharmacological Investigations in the Epicatechin Gastroprotective Effect." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/708156.

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Previous studies of the gastroprotective activity of plants have highlighted the importance of the polyphenolic compound epicatechin (EC) in the treatment of gastric ulcers. This paper aimed to evaluate and characterize the gastroprotective mechanism of action of EC using male rats. The gastroprotective action of EC was analyzed in gastric ulcers induced by ethanol or indomethacin. The involvement of sulfhydryl (SH) groups,K+ATPchannels,α2adrenoceptors, gastric antisecretory activity, and the amount of mucus in the development of gastric ulcers were investigated. The lowest effective dose of E

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33

Mahoney, Megan K., John H. Barnes, David Wiercigroch, and Mary C. Olmstead. "Pharmacological investigations of a yohimbine–impulsivity interaction in rats." Behavioural Pharmacology 27, no. 7 (2016): 585–95. http://dx.doi.org/10.1097/fbp.0000000000000251.

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34

Mishin, M. A., E. G. Guseva, M. A. Dumpis, P. D. Shabanov, and L. B. Piotrovskii. "Diesters of glutaminic acid: Synthesis and primary pharmacological investigations." Pharmaceutical Chemistry Journal 25, no. 4 (1991): 246–48. http://dx.doi.org/10.1007/bf00772105.

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35

Nur, Tanzina, Md Torequl Islam, Syedul Alam, M. Mohi Uddin Chowdhury, Ana Amelia Carvalho Melo-Cavalcante, and Rivelilson Mendes de Freitas. "Pharmacological investigations of organic crude fractions of Dysophylla auricularia." Oriental Pharmacy and Experimental Medicine 15, no. 3 (2015): 207–15. http://dx.doi.org/10.1007/s13596-015-0190-x.

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36

Manolov, Ilia, and Nicolay D. Danchev. "Synthesis and Pharmacological Investigations of Some 4-Hydroxycoumarin Derivatives." Archiv der Pharmazie 336, no. 2 (2003): 83–94. http://dx.doi.org/10.1002/ardp.200390010.

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37

Khan, Asim Ali, Fouzia Bashir, Jamal Akhtar, Nighat Anjum, and Shah Alam. "Phyto-chemical and pharmacological investigations of Aftimoon (Cuscuta reflexa)." International Journal of Unani and Integrative Medicine 3, no. 3 (2019): 45–48. http://dx.doi.org/10.33545/2616454x.2019.v3.i3a.95.

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38

Dobric, Silva, Silvana Petrovic, Jelena Kukic-Markovic, Stevan Samardzic, and Violeta Milutinovic. "Pharmacological characterization of Cirsium ligulare Boiss. (Asteraceae) herb decoction." Vojnosanitetski pregled 74, no. 7 (2017): 652–58. http://dx.doi.org/10.2298/vsp160422086d.

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Background/Aim. Data on phytochemical and pharmacological investigations of genus Cirsium Mill. (Asteraceae) are scarce. Some data suggest that decoctions or infusions prepared from these plants are used in folk medicine as tonics, particularly in inflammatory, liver and stomach diseases. So far there have been no pharmacological investigations related to Cirsium ligulare (C. ligulare) Boiss. Accordingly, the aim of this study was to estimate antioxidative, anti-inflammatory and gastroprotective activities of aqueous extracts of C. ligulare herb prepared as 5% and 10% decoctions. Methods. Anti

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Islam, Shahidul, and Rupa Dev. "Chemical, Biological & Pharmacological Investigations of Different Fractional Extracts of Passiflora edulis Sims. (Family: Passifloraceae)." Pharmaceutics and Pharmacology Research 5, no. 3 (2022): 01–11. http://dx.doi.org/10.31579/2693-7247/062.

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In the evaluation of antimicrobial activity, antibacterial activity of ethanol, chloroform & n-hexane extracts of P. edulis was tested against 10 bacteria at concentrations of 500µg/disc. Standard antibiotic disc of Azithromycin (30 µg/disc) was used for the comparison. The extracts showed no activity against gm (+ve) & gm (-ve) bacteria at a concentration of 500 µg/disc. Antifungal activity of ethanol, chloroform & n-hexane extracts of P. edulis was tested against 7 fungi at concentrations of 500µg/disc. Standard antifungal disc of Fluconazole (30 µg/disc) was used for the compari

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40

Md., Israrul Haque, and Farid Alam Ansari Md. "An Observational Assessment of the Knowledge and Awareness of General Practitioners Concerning the Management of Hypertension." International Journal of Pharmaceutical and Clinical Research 14, no. 8 (2022): 108–13. https://doi.org/10.5281/zenodo.13345345.

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<strong>Aim:</strong> To assess awareness and approach of general practitioners towards hypertension management. <strong>Methodology:</strong> The present study was conducted in Department of General Medicine, Netaji Subhas medical College and Hospital, Bihta, Patna, Bihar, India for 1 year, among 100 general practitioners who agreed to participate in the study. All were enrolled after obtaining their written consent. Data pertaining to subjects such as name, age, gender etc. was recorded. A detailed questionnaire was prepared which comprised of information regarding the techniq

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Chougule, Poonam, Kailasam Koumaravelou, and Nilesh Chougule. "Extraction, Isolation, Characterisation and Pharmacological Investigations of Beta Escin from Horse Chest Nut Seed Extract." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 04 (2023): 977–86. http://dx.doi.org/10.25258/ijpqa.14.4.25.

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Horse chestnut seeds (Aesculus hippocastanum) have long been recognized for their potential therapeutic properties, particularly due to the presence of bioactive compounds like beta-escin. This study aimed to comprehensively explore the extraction, isolation, characterization, and pharmacological investigations of beta escin from horse chestnut seed extract. Beta escin was extracted from horse chestnut seeds through a series of solvent extraction and purification steps. The isolated compound was then characterized using various analytical techniques, including UV, IR, DSC, X-RPD and GC/MS. Pha

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42

Mohiuddin, Abdul Kader, and Sayra Akter Lia. "Medicinal & Biological Investigations of Ficus Racemosa." Forestry & Agriculture Review 1, no. 2 (2020): 29–81. http://dx.doi.org/10.47285/far.v1i2.43.

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Ficus racemosa is a traditional medicinal plant found in Southeast Asia and Australia. It is commonly known as 'gular'or ‘Dumur’. Owing to the presence of β-sitosterol it decreases the blood glucose concentration. Many active constituents isolated from different parts of this plant exhibit useful pharmacological activity. The objective of this dissertation is to identify the biological activity of the roots of an indigenous medicinal plant, viz., Ficus racemosa (Family: Moraceae) and to evaluate the possible phytochemical and pharmacological profiles of the crude extracts. Some chemical and bi

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Dávid, Csilla Zsuzsanna, Judit Hohmann, and Andrea Vasas. "Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review." Molecules 26, no. 9 (2021): 2794. http://dx.doi.org/10.3390/molecules26092794.

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Cyperaceae is a cosmopolitan plant family with approx. 5000 species distributed worldwide. Several members of this family are used in traditional medicines for the treatment of different diseases. In the last few decades, constituents with great chemical diversity were isolated from sedges, and a wide range of biological activities were detected either for crude extracts or for pure compounds. Among the isolated compounds, phenolic derivatives are the most important, especially stilbenoids, and flavonoids. To date, more than 60 stilbenoids were isolated from 28 Cyperaceae species. Pharmacologi

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44

Stambolov, Ivan, Aleksandar Shkondrov, and Ilina Krasteva. "Astragalus glycyphyllos L.: Phytochemical constituents, pharmacology, and biotechnology." Pharmacia 70, no. 3 (2023): 635–41. http://dx.doi.org/10.3897/pharmacia.70.e107989.

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Astragalus glycyphyllos is a widely distributed plant found in Bulgaria that has been used in the folk medicine of the country for decades as an antihypertensive, diuretic, and anti-inflammatory. This review article is focused on the traditional usage, phytochemical studies, pharmacological activity, and biotechnology of this species. Recent progress in the phytochemical investigation led to the identification of different flavonoids, triterpenoid saponins, sterols, volatiles, etc. Many pharmacological studies, performed on extracts and pure compounds, revealed promising antiproliferative, cyt

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45

Rafi, Gulshan, and Habib Ur-Rehman. "Pharmacological Evaluation of Trianthema portulacastrum." International Journal of Advanced Multidisciplinary Research and Studies 4, no. 4 (2024): 1009–17. http://dx.doi.org/10.62225/2583049x.2024.4.4.3141.

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Trianthema portulacastrum is known for its important biological activities and its various parts are used in the folk medicine system to treat various diseases. The extracts of the plant have shown antioxidant, antibacterial, antifungal, antithelmintic, antiglomerulosclerosis anticancer, anti-inflammatory, hepatotoxic and hypolipidimic activities. Our investigations on the extracts of the plant have shown that they possess promising antioxidant activity. The extracts also showed moderate antibacterial activity indicating that they have substantial DPPH and ABTs free radical scavenging capabili

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Kumar, Ravi, Girednra Kumar Gautam, and Aarti Chopra. "Pharmacological Activity of Earthworms." Science Progress and Research 1, no. 4 (2021): 264–67. http://dx.doi.org/10.52152/spr/2021.144.

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Earthworms have a significant role in soil structure and organic matter dynamics. They make up a considerable amount of macrofauna biomass and are a prominent component of soil fauna communities in most habitats. Soil structure, water flow, nutrient dynamics, and plant development are all influenced by earthworms. Earthworms have long been recognized for their medicinal benefits. Because earthworm tissues are a rich source of proteins, peptides, enzymes, and physiologically active compounds, extracts produced from them have been utilized to treat a variety of illnesses. Several investigations

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Kumar, Ravi, Girednra Kumar Gautam, and Aarti Chopra. "Pharmacological activity of earthworms." Science Progress and Research 1, no. 4 (2021): 357–60. http://dx.doi.org/10.52152/spr/2021.140.

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Abstract:

Earthworms have a significant role in soil structure and organic matter dynamics. They make up a considerable amount of macrofauna biomass and are a prominent component of soil fauna communities in most habitats. Soil structure, water flow, nutrient dynamics, and plant development are all influenced by earthworms. Earthworms have long been recognized for their medicinal benefits. Because earthworm tissues are a rich source of proteins, peptides, enzymes, and physiologically active compounds, extracts produced from them have been utilized to treat a variety of illnesses. Several investigations

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48

Ali Esmail Al-Snafi. "Medicinal plants with hypoglycemic effect: A review." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 147–73. http://dx.doi.org/10.30574/gscbps.2023.24.1.0274.

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Diabetes mellitus is one of the most common endocrine diseases. Due to its complications, it caused significant mortality. Insulin and oral antidiabetic drugs were associated with many side effects. The search for more effective and safer hypoglycemic agents is one of the important areas of investigation. The pharmacological investigations revealed that several medicinal plants showed hypoglycemic effects by many mechanisms. The current review highlighted the medicinal plants with antidiabetic effect.

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49

Ali, Esmail Al-Snafi. "Medicinal plants with hypoglycemic effect: A review." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 147–73. https://doi.org/10.5281/zenodo.8265215.

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Abstract:

Diabetes mellitus is one of the most common endocrine diseases. Due to its complications, it caused significant mortality. Insulin and oral antidiabetic drugs were associated with many side effects. The search for more effective and safer hypoglycemic agents is one of the important areas of investigation. The pharmacological investigations revealed that several medicinal plants showed hypoglycemic effects by many mechanisms. The current review highlighted the medicinal plants with antidiabetic effect.

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50

Kuldeep, T. Padhyar, S. Patil Rajendra, and B. Wadwale Navanand. "A brief review on Triazole and its Pharmacological Application." International Journal of Current Science Research and Review 05, no. 01 (2022): 212–25. https://doi.org/10.47191/ijcsrr/V5-i1-25.

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  Abstract : The triazole core is one of the most imperative and well known heterocycles which is composed of nitrogen atom which forms natural products with medicinal claims. Triazole moiety is present as a principal structural component in the drug categories such as antimicrobial, anti-inflammatory, analgesic, antineoplastic, antimalarial, antiviral, antihypertensive, local anaesthetic, antianxiety, anti-Parkinson′s, antidepressant, antioxidant, antihistaminic, antitubercular, antidiabetic etc. The broad and potent activity of triazole and their derivatives has established them a

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