Relevant bibliographies by topics / Phenylpiperazine substitutee

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  2. Dissertations / Theses

Academic literature on the topic 'Phenylpiperazine substitutee'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Phenylpiperazine substitutee"

1

Verdonk, M. L., J. W. Voogd, J. A. Kanters, et al. "Structure and Serotonin 5-HT2C Receptor Activity of ortho- and meta-Substituted Phenylpiperazines." Acta Crystallographica Section B Structural Science 53, no. 6 (1997): 976–83. http://dx.doi.org/10.1107/s0108768197009142.

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The structural characteristics of ortho- and meta-substituted phenylpiperazines have been investigated in order to understand their actions at the serotonin 5-HT2c receptor. The crystal structures of the 4-methylated analogues of two phenylpiperazines that are already known as 5-HT2c ligands, 1-(1-naphthyl)-4-methylpiperazine (1NMP) and 1-[(3-trifluoromethyl)phenyl]-4-methylpiperazine (TFMPMP), and those of two novel 5-HT2c ligands, 1-(2-methoxyphenyl)piperazine (oMPP) and 1-(3-methoxyphenyl)piperazine (mMPP), are determined. Molecular mechanics calculations are performed to calculate the ener
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2

Wang, Cheng Jun, Shan Shan Gong, and Qi Sun. "Synthesis of an Akt Inhibitor-IV Analogue via an Amine-Exchange Reaction." Advanced Materials Research 1023 (August 2014): 47–50. http://dx.doi.org/10.4028/www.scientific.net/amr.1023.47.

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3

Padrtová, Tereza, Pavlína Marvanová, Renáta Kubínová, et al. "Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity." Current Organic Synthesis 17, no. 7 (2020): 576–87. http://dx.doi.org/10.2174/1570179417666200619132218.

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Background: The indole derivatives and the N-phenylpiperazine fragment represent interesting molecular moieties suitable for the research of new potentially biologically active compounds. This study was undertaken to identify if indol-2-carboxylic acid esters containing N-phenylpiperazine moiety possess acetylcholinesterase and butyrylcholinesterase inhibitory activity. Materials and Methods: The study dealt with the synthesis of a novel series of analogs of 1H-indole-2- carboxylic acid and 3-methyl-1H-indole-2-carboxylic acid. The structure of the derivatives was represented by the indolylcar
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4

Špirková, Katarína, Rudolf Kada, Jaroslav Kováč, Viera Knoppová, Miroslav Dzuroška, and Margita Margušová. "A study of reactions of 5-substituted furfurylidene derivatives with secondary amines." Collection of Czechoslovak Chemical Communications 50, no. 2 (1985): 459–69. http://dx.doi.org/10.1135/cccc19850459.

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The paper describes preparation of 5-bromo-, 5-nitro-, 5-phenylsulphonyl-, and 5-phenylthio-2-furfurylidene derivatives and investigation of their reactions with N-phenylpiperazine, morpholine, piperidine, and pyrrolidine. Kinetics of the reactions have been followed, and UV, IR, and 1H NMR spectra of the compounds produced are interpreted.
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5

Nematollahi, Davood, and Amene Amani. "Electrochemical synthesis of the new substituted phenylpiperazines." Journal of Electroanalytical Chemistry 651, no. 1 (2011): 72–79. http://dx.doi.org/10.1016/j.jelechem.2010.10.024.

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6

Štetinová, Jarmila, Adolf Jurášek, Jaroslav Kováč, Miloslava Dandárová, and Oľga Rajniaková. "Synthesis and properties of 4-alkylaminomethyl and 4-alkoxymethyl derivatives of 5-methyl-2-furancarboxylic acid." Collection of Czechoslovak Chemical Communications 51, no. 10 (1986): 2186–92. http://dx.doi.org/10.1135/cccc19862186.

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New β-substituted amines and ethers of the furan series (II-V) were prepared by reaction of methyl 4-bromomethyl-5-methyl-2-furancarboxylate (I) with nucleophiles such as pyrrolidine, piperidine, morpholine, N-phenylpiperazine, cyclohexylamine, 2-methylcyclohexylamine, N-ethylaniline, p-toluidine, ethanol, butanol and salicylaldehyde. The structure of the products was confirmed by their analytical and spectral data. Kovats indices I for the products were determined using gas-liquid chromatography.
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7

Acosta Quintero, Lina M., Alirio Palma, Justo Cobo, and Christopher Glidewell. "A versatile synthesis of cyclic dipeptides using the stepwise construction of the piperazine-2,5-dione ring from simple precursors: synthetic sequence and the structure of a representative product, (3RS)-4-(2-allyl-3,5-dimethylphenyl)-1-benzyl-3-phenylpiperazine-2,5-dione." Acta Crystallographica Section C Structural Chemistry 74, no. 2 (2018): 159–65. http://dx.doi.org/10.1107/s2053229618000037.

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A versatile synthesis of multiply substituted cyclic dipeptides has been designed, based on the stepwise construction of the piperazine-2,5-dione ring using molecular fragments from four different precursor molecules. Starting from substituted 2-allylanilines, reaction with methyl 2-bromo-2-phenylacetate yields the corresponding methyl 2-(2-allylanilino)-2-phenylacetates, which react with haloacetyl chlorides to give methyl 2-[N-(2-allylphenyl)-2-haloacetamido]-2-phenylacetates, which then undergo ring closure with benzylamine to yield the corresponding cyclic dipeptides of type 4-(2-allylphen
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8

Lee, Boeun, Michelle Taylor, Suzy A. Griffin, et al. "Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands." Molecules 26, no. 11 (2021): 3182. http://dx.doi.org/10.3390/molecules26113182.

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N-phenylpiperazine analogs can bind selectively to the D3 versus the D2 dopamine receptor subtype despite the fact that these two D2-like dopamine receptor subtypes exhibit substantial amino acid sequence homology. The binding for a number of these receptor subtype selective compounds was found to be consistent with their ability to bind at the D3 dopamine receptor subtype in a bitopic manner. In this study, a series of the 3-thiophenephenyl and 4-thiazolylphenyl fluoride substituted N-phenylpiperazine analogs were evaluated. Compound 6a was found to bind at the human D3 receptor with nanomola
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9

Malík, Ivan, Marián Bukovský, Fils Andriamainty, and Jana Gališinová. "Antimicrobial activity of meta-alkoxyphenylcarbamates containing substituted N-phenylpiperazine fragment." Brazilian Journal of Microbiology 43, no. 3 (2012): 959–65. http://dx.doi.org/10.1590/s1517-83822012000300016.

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10

Gallicchio, Steven N., and Ian M. Bell. "Convenient synthesis of 1,3-substituted-6-phenylpiperazin-2-ones." Tetrahedron Letters 50, no. 27 (2009): 3817–19. http://dx.doi.org/10.1016/j.tetlet.2009.04.036.

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Dissertations / Theses on the topic "Phenylpiperazine substitutee"

1

Galmier, Marie-Josèphe. "Etude in vivo et in vitro des réactions de n-dephenylation et nih shift sur des phenylpiperazines substituées." Clermont-Ferrand 1, 1992. http://www.theses.fr/1992CLF15001.

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