Academic literature on the topic 'Phthalazine'
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Journal articles on the topic "Phthalazine"
Mourad, Asmaa Kamal, Abdelmoneim Abdelsalam Makhlouf, Ahmed Yousef Soliman, and Samar Ahmed Mohamed. "Phthalazines and phthalazine hybrids as antimicrobial agents: Synthesis and biological evaluation." Journal of Chemical Research 44, no. 1-2 (October 29, 2019): 31–41. http://dx.doi.org/10.1177/1747519819883840.
Full textWasfy, A. A. F. "Fused Heterocycles. Part I. Synthesis of Some Annelated 1,2,4-Triazole Systems from [4-(1H-Benzimidazol-2-yl)-Phthalazin-1-Yl]Hydrazine." Journal of Chemical Research 2003, no. 8 (August 2003): 457–58. http://dx.doi.org/10.3184/030823403103174786.
Full textXu, Jing. "Research on Synthesis of Triazine Ring and its Isomerization." Applied Mechanics and Materials 686 (October 2014): 26–30. http://dx.doi.org/10.4028/www.scientific.net/amm.686.26.
Full textPlasseraud, Laurent, Hélène Cattey, and Philippe Richard. "Self-assembly Through Non-coordinating Intermolecular Forces, Part 2 [1]. Synthesis, Crystal Structure and Packing of [Cu2(μ-phthalazine)3(phthalazine)2][CF3SO3]2." Zeitschrift für Naturforschung B 63, no. 10 (October 1, 2008): 1169–74. http://dx.doi.org/10.1515/znb-2008-1005.
Full textHabibi, Davood, Nosratollah Mahmoudi, and Omid Marvi. "Green Procedure for the Synthesis of Phthalazino[2,3‐b]phthalazine‐5,7,12,14‐tetraones." Synthetic Communications 37, no. 18 (September 1, 2007): 3165–71. http://dx.doi.org/10.1080/00397910701545247.
Full textHabibi, Davood, Nosratollah Mahmoodi, and Omid Marvi. "Montmorillonite K-10 clay as reusable heterogeneous catalyst for the microwave-mediated solventless synthesis of phthalazinetetraones." Canadian Journal of Chemistry 85, no. 2 (February 1, 2007): 81–84. http://dx.doi.org/10.1139/v06-189.
Full textÇelik, Ömer, Semra İde, Mustafa Kurt, and Şenay Yurdakul. "Dichlorobis(phthalazine)zinc(II)." Acta Crystallographica Section E Structure Reports Online 60, no. 8 (July 17, 2004): m1134—m1136. http://dx.doi.org/10.1107/s1600536804016915.
Full textCai, Mingjian. "5-Bromophthalazine hemihydrate." Acta Crystallographica Section E Structure Reports Online 68, no. 8 (July 10, 2012): o2421. http://dx.doi.org/10.1107/s1600536812030358.
Full textSoliman, Saied M., Raghdaa A. Massoud, Hessa H. Al-Rasheed, and Ayman El-Faham. "Molecular and Supramolecular Structures of Cd(II) Complexes with Hydralazine-Based Ligands; A New Example for Cyclization of Hydrazonophthalazine to Triazolophthalazine." Crystals 11, no. 7 (July 15, 2021): 823. http://dx.doi.org/10.3390/cryst11070823.
Full textÇelik, Ömer, Semra İde, Mustafa Kurt, and Şenay Yurdakul. "Dibromobis(phthalazine-κN2)zinc(II)." Acta Crystallographica Section E Structure Reports Online 60, no. 4 (March 20, 2004): m424—m425. http://dx.doi.org/10.1107/s1600536804004908.
Full textDissertations / Theses on the topic "Phthalazine"
Sheppard, Christopher Lorenzo. "Magnetostructural correlations in polynuclear complexes of phthalazine-based tetra- and hexadentate ligands." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ34227.pdf.
Full textLi, Jiyang [Verfasser]. "Investigation of Phthalazine, Quinazoline and Pyrimidine Derivatives as ABCG2 Inhibitors / Jiyang Li." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1167857135/34.
Full textKuzelka, Jane 1975. "Modeling the active sites of diiron and dicopper metalloproteins with napthyridine-, phthalazine-, and diethynylbenzene-based ligands." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/30016.
Full textVita.
Includes bibliographical references.
Chapter 1. Bio-Inspired Reactions of Diiron Centers with Dioxygen A variety of biological systems employ carboxylate-bridged diiron centers to achieve substrate oxidation using dioxygen, and numerous small molecule model compounds have been synthesized in order to mimic this chemistry in the absence of a protein scaffold. In this introductory chapter, a brief overview is presented of ligand systems that have been used to prepare diiron complexes, and the subsequent oxidation chemistry of these systems is outlined. Chapter 2. Carboxylate, Phosphodiester, and Hydroxide-Bridged Diiron(II) Complexes with a Sterically Hindered Phthalazine Ligand The synthesis and crystallographic characterization of a series of diiron(II) complexes with a sterically hindered bridging phthalazine ligand are presented. The compounds [Fe₂(Ph₄bdptz)([mu]-O₂CR)₂]²⁺ (R = CH₃ (3); C₂H₅ (4); CH₂Ph (5); t-C₄H₉ (6)), [Fe₂(Ph₄bdptz)([mu]-O₂P(OPh)₂)₂]²⁺ (7), and [Fe₂(Ph₄bdptz) ([mu]-OH)(MeCN)₂]³⁺ (8) were prepared as small molecule models of the catalytic sites in non-heme carboxylate-bridged diiron enzymes. The phenyl rings of Ph4bdptz form a hydrophobic size-constrained pocket in which additional ligands can be accommodated, and they block the possible formation of tetranuclear species. As the steric bulk of the ancillary ligands is increased, the carboxylates shift from a syn, anti to a syn, syn coordination mode, and the Mossbauer spectra of the diiron(II) compounds clearly reflect the symmetry of the iron coordination environment. The oxidation chemistry of the diiron(II) compounds is presented.
(cont.) Chapter 3. Modeling Features of the Non-Heme Diiron Cores in O0-Activating Enzymes through the Synthesis, Characterization, and Oxidation of 1,8-Naphthyridine-Based Complexes Multidentate naphthyridine-based ligands were used to prepare a series of diiron(II) complexes. The compounds [Fe₂(BPMAN)([mu]-O₂CPh)₂](OTf)₂ (1), [Fe₂(BPMAN)([mu]-OR) ([mu]-0₂CAr[superscript]Tol)] (OTf)2 (R = H (2); CH₃ (3)), [Fe₂(BBAN)([mu]-0₂CAr[superscript]Tol)₃]-(OTf) (4), and [Fe₂(BEAN) ([mu]-O₂CAr[superscript]Tol)₃](OTf) (5) were prepared as models of the active sites of non-heme diiron enzymes. The rigorously enforced dinuclear core allows the reactivity of the diiron unit to be evaluated. Upon oxidation of these compounds, there is evidence for the formation of a ([mu]-oxo)diiron(III) unit, a mixed-valent ([mu]-oxo)Fe(II)Fe(III) species, and oxidative N-dealkylation. The electrochemical properties of the compounds were correlated with the observed dioxygen reactivity, and Mossbauer spectroscopic properties of the diiron(II) complexes were also investigated. Chapter 4. Modeling the Syn Disposition of Nitrogen Donors at the Active Sites of Carboxylate-Bridged Diiron Enzymes. Enforcing Dinuclearity and Kinetic Stability with a 1,2-Diethynylbenzene-Based Ligand The syn coordination of histidine residues at the active sites of several carboxylate-rich non-heme diiron enzymes has not been effectively reproduced with small molecule model compounds. In this study, ligands derived from 1,8- naphthyridine, phthalazine, and 1,2-diethynylbenzene were employed to mimic this geometric feature ...
by Jane Kuzelka.
Ph.D.
Alzahrani, Nada Saleh. "The Synthesis and Characterization of the Bis-Substituted Phthalazine Using Bis-Substituted Isoindoline as Starting Material and Their Metals Complexes &The Synthesis and Charectrization of the Schiff Base Ligands with a Variety of Metals." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1408102563.
Full textHoughton, Ralph Warren. "Synthesis of 1-substituted phenyl phthalazines." Scholarly Commons, 1990. https://scholarlycommons.pacific.edu/uop_etds/2201.
Full textRagunathan, Ramanaranjinie. "Studies of certain benzimidazoles, phthalazines and phthalimides." Thesis, Brunel University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292494.
Full textJohnsen, Matthias. "Neue Antithrombotika mit Phthalazin- und Pyridazin-Partialstrukturen." [S.l.] : [s.n.], 2002. http://www.diss.fu-berlin.de/2002/257/index.html.
Full textJožef, Mađari. "Sinteza, strukturna, fizičko-hemijska i biološka karakterizacija novih N-heterocikličnih liganada i njihovih kompleksa sa jonima prelaznih metala." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=107656&source=NDLTD&language=en.
Full textThe synthesis of new ligands dihydrochloride salt of 2,6-diacetylpyridne bis(phthalazine-1hydrazone) (Hz2DAP•2HCl), 2,6-diacetylpiridine bis(3- chloropyridazine-6-hydrazone) (Hp2DAP), di(2-pyridyl)ketone 3-chloropyridazine- 6-hydrazone (HpDPK), di(2-pyridyl)ketone phthalazine-1-hydrazone (HzDPK) and pyridine-2-carbaldehide phthalazine-1-hydrazone (HzPY) have been described. All the ligands contain pyridine and diazine core and all of them have only nitrogen donor atoms. During the complex formation the deprotonation of ligands takes places. All of the ligands have been characterized by elemental analysis,thermoanalytical methods and IR spectroscopy. In some cases also by NMR spectroscopy and X-ray structural analysis.Co(II), Ni(II), Cu(II) and Zn(II) salts were used for the synthesis of the coordinational compounds. The obtained complexes were characterized by elemental analysis, molar conductivity and magnetic measurements, IR spectroscopy and thermoanalytical methods. At least one complex of each series were characterized by X-ray structural analysis.The antimicrobial activity of some of the compounds toward Gram-positive/Gram- negative bacteria furthermore, the cytotoxic, antiproliferative and inhibitory activity toward sensitive parental andmultiresistant T-lymphoma cancer cells have also been carried out. It can be concluded that some of the compounds exhibit outstanding antimicrobial, cytotoxic, antiproliferative, and inhibitory activity.
Chang, Wen-Fu, and 張文福. "Phthalazine derivatives synthesize." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/37358420057208271610.
Full text國立中央大學
化學研究所
92
The heterocycles involving 1,4-dihydazinophthalazine (DHPH) as a building block have been paid considerable attention due to the significant biological applications. 1,4-dihydrazinophthalazine 1 reacted with 14、15 and 16. The ratio between 12 and 13, is dependent upon the pH of medium and temperature.1,4-dihydrazinophthalazine 1 reacted with aldehyde, followed by an oxidative cyclization to gave 22、28 and 29. When compound 29 was treated with 31 in ethanol under reflux for 12 h, it was also complex 32 .Upon irradiation with UV light, complex 32 changed color from yellow to red. The chemistry is yet to pursuit.
Hung, Cheng-Lung, and 洪正龍. "Synthesis and Application of Ruthenium Complex Dyes Containing 1-(pyridin-2-yl)phthalazine Derivatives for Dye-sensitized Solar Cells (DSSCs)." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/ynhygq.
Full text國立臺北科技大學
有機高分子研究所
97
Global environment concerns and the finite nature of fossil fuels have led to a growth of interest in the development of renewable energy. In order to maintain social and economic development, the solar energy is one of the best candidates of making a suitable transition to renewable fuels. Dye-sensitized solar cells (DSSCs) are currently attracting widespread interest for the conversion of sunlight into electricity because of their low cost and high efficiency. Charge separation is initiated at the dye, bound at the interface of an inorganic semiconductor like titanium dioxide and a holetransport material like the electrolyte. Careful design of the dye can minimize loss mechanisms and improve light harvesting. We synthesized new ruthenium(II) complex dyes containing novel ligands to improve the efficiency for DSSCs.
Books on the topic "Phthalazine"
Brown, D. J. Cinnolines and Phthalazines. Hoboken, NJ, USA: John Wiley & Sons, Ltd, 2005. http://dx.doi.org/10.1002/0471744123.
Full textRagunathan, Ramanaranjinie. Studies of certain benzimidazoles, phthalazines and phthalimides. Uxbridge: Brunel University, 1991.
Find full textTaylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Cinnolines and Phthalazines, Supplement 2. Wiley & Sons, Incorporated, John, 2005.
Find full textCastle, Raymond N. Condensed Pyridazines Including Cinnolines and Phthalazines. Wiley & Sons, Incorporated, John, 2009.
Find full textSimpson, J. C. Pyridazine and Pyrazine Rings : (Cinnolines, Phthalazines, and Quinoxalines). Wiley & Sons, Incorporated, John, 2009.
Find full textTaylor, Edward C., Peter Wipf, and Desmond J. Brown. Cinnolines and Phthalazines: Chemistry of Heterocyclic Compounds, Supplement II (Chemistry of Heterocyclic Compounds: A Series Of Monographs). Wiley-Interscience, 2005.
Find full textBook chapters on the topic "Phthalazine"
Horkel, Ernst. "Metalation of Pyridazine, Cinnoline, and Phthalazine." In Topics in Heterocyclic Chemistry, 223–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/7081_2012_97.
Full textWinkelmann, Jochen. "Diffusion coefficient of 1,4-diphenylbenzo[g]phthalazine in tetrahydro-furan-d8." In Diffusion in Gases, Liquids and Electrolytes, 1200. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_976.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of hexanuclear copper(II) chloro complex with glycerol phthalazine." In Magnetic Properties of Paramagnetic Compounds, 1087–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_611.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of hexanuclear copper(II) bromo complex with glycerol phthalazine." In Magnetic Properties of Paramagnetic Compounds, 1089–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_612.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of hexanuclear copper(II) nitrato complex with glycerol phthalazine." In Magnetic Properties of Paramagnetic Compounds, 1091–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_613.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of octanuclear copper(II) chloro complex with pentaerythritol phthalazine." In Magnetic Properties of Paramagnetic Compounds, 1096–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_616.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of octanuclear copper(II) bromo complex with pentaerythritol phthalazine." In Magnetic Properties of Paramagnetic Compounds, 1098–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_617.
Full textPatel, Natu R. "Phthalazines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs, 323–760. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186978.ch2.
Full textWinkelmann, Jochen. "Diffusion coefficient of 1,4-diphenylbenzo[g]phthalazine ion(2-) in tetrahydro-furan-d8." In Diffusion in Gases, Liquids and Electrolytes, 1201. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_977.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of tetranuclear copper(II) complex with novel dendritic poly(phthalazine) ligand." In Magnetic Properties of Paramagnetic Compounds, 1057–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54237-8_596.
Full textConference papers on the topic "Phthalazine"
Raposo, M., Ana Sampaio, and G. Kirsch. "Synthesis of 1-amino-4-(2´-thienyl)phthalazine Derivatives." In The 8th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01948.
Full textRaposo, M., and Sara Fernandes. "Synthesis and characterization of novel phthalazine based push-pull heterocyclic systems for DSSC." In The 19th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-a020.
Full textRaposo, M., and Sara Fernandes. "Synthesis and characterization of novel thienyl-phthalazine based heterocyclic systems functionalized with (bi)thiophene moieties." In The 21st International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04797.
Full textAndrejevic, Tina, Dusan Milivojevic, Darko Ašanin, Nevena Stevanović, Jasmina Nikodinovic-Runic, Miloš Djuran, and Biljana Glišić. "DNA/BSA binding affinities and <em>in vivo</em> toxicity of dinuclear silver(I) complexes with phthalazine." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07371.
Full textChen, Tai-Lin, Vicky Jain, Yi-Wen Lin, Tsann-Long Su, and Te-Chang Lee. "Abstract 3852: Development of1,2-bis(hydroxymethyl)benzo[g]pyrrolo[2,1-a]phthalazine hybrids as potent anticancer agents to small cell lung cancer." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3852.
Full textChen, Tai-Lin, Vicky Jain, Yi-Wen Lin, Tsann-Long Su, and Te-Chang Lee. "Abstract 3852: Development of1,2-bis(hydroxymethyl)benzo[g]pyrrolo[2,1-a]phthalazine hybrids as potent anticancer agents to small cell lung cancer." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3852.
Full textChen, Tai-Lin, Vicky Jain, Anilkumar S. Patel, Yi-Wen Lin, Tsann-Long Su, and Te-Chang Lee. "Abstract A002: Discovery of bis(hydroxymethyl)benzopyrrolo[2,1-a]phthalazine derivatives as orally bioavailable antitumor agents with anti-angiogenic and DNA cross-linking activities." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-a002.
Full textLeng, Xiaohui, Yiming Wang, and Fei Wang. "Sulfonation of Poly(phthalazinone ether ketone) for MEMS humidity sensor." In 2018 IEEE Micro Electro Mechanical Systems (MEMS). IEEE, 2018. http://dx.doi.org/10.1109/memsys.2018.8346605.
Full textYuan, Kuanyu, Cheng Liu, Hongmin Duan, Manxia Zhang, and Xigao Jian. "Preparation and Characterization of the Phthalazinone Structure-based Microporous Organic Polymer." In 2015 International Conference on Materials, Environmental and Biological Engineering. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/mebe-15.2015.200.
Full textEl Rayes, Samir, Ibrahim Ali, hamdy Abd Elazeem, and Sara Eltorky. "Convenient Synthesis of Some Novel 4-Benzyl-1(2H)-Phthalazinone Derivatives of expected anticancer activity." In The 23rd International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecsoc-23-06605.
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