Relevant bibliographies by topics / PHYTOCHEMICAL CANDIDATES

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'PHYTOCHEMICAL CANDIDATES'

Author: Grafiati
Published: 9 November 2023
Last updated: 31 July 2025

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Journal articles on the topic "PHYTOCHEMICAL CANDIDATES"

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Grădinaru, Teodora-Cristiana, Marilena Gilca, Adelina Vlad, and Dorin Dragoș. "Relevance of Phytochemical Taste for Anti-Cancer Activity: A Statistical Inquiry." International Journal of Molecular Sciences 24, no. 22 (2023): 16227. http://dx.doi.org/10.3390/ijms242216227.

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Targeting inflammation and the pathways linking inflammation with cancer is an innovative therapeutic strategy. Tastants are potential candidates for this approach, since taste receptors display various biological functions, including anti-inflammatory activity (AIA). The present study aims to explore the power different tastes have to predict a phytochemical’s anti-cancer properties. It also investigates whether anti-inflammatory phytocompounds also have anti-cancer effects, and whether there are tastes that can better predict a phytochemical’s bivalent biological activity. Data from the Plan
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Eskundari, Ratna Dewi, Tri Wiharti, Nur Rokhimah Hanik, Fety Fatimah, Umi Salamah, and Antik Murwani. "Phytochemical test of several eco-handsanitizer candidates." Jurnal Biologi Tropis 22, no. 1 (2022): 297–303. http://dx.doi.org/10.29303/jbt.v22i1.3258.

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Ecoenzymes are natural ingredients formed from the fermentation of fruit and or vegetable residues that have many benefits. One of the benefits of ecoenzymes is that they can be used as eco-handsanitizers; which can be used as a candidate for handsanitizer for those who are allergic to alcohol-based handsanitizer. This study aims to determine the pH, antibacterial, antiviral, and antifungal content of the candidate eco-handsanitizer solution through alkaloid, flavonoid, and saponin test, also fungal-inhibition test. The candidate eco-handsanitizer solution was made from an ecoenzyme solution d
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Sadiq, Shifana C., Maria Pellissery Joy, Sreekumar U. Aiswarya, et al. "Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules." Exploration of Drug Science 2, no. 6 (2024): 744–84. http://dx.doi.org/10.37349/eds.2024.00073.

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Phytochemicals, the bioactive compounds derived from plants, play a significant role in modulating pathways leading to cancer and inflammation, rendering themselves promising candidates for therapeutic interventions. This review explores the multifaceted potential of various phytochemicals in modulating key mechanisms involved in the development and progression of cancer and inflammation. The diverse array of phytochemicals discussed here encompasses polyphenols, flavonoids, alkaloids, terpenoids, and many others, each with distinct molecular targets and modes of action. This review is an atte
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JR, Naidu. "Phytochemical and Chemical Characterization of Centella Asiatica and Cymbopogan Citratus Extracts." Bioequivalence & Bioavailability International Journal 7, no. 2 (2023): 1–17. http://dx.doi.org/10.23880/beba-16000213.

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Epidemiological studies have consistently linked abundant consumption of foods of plant origin, to the reduced risk of cancer. The present study was conducted to perform the of chemical and phytochemical characterization of selected medicinal herbs Centella asiatica and Cymbopogan citratus which are commonly used in Malaysian diet. Phytochemical and chemical characterization of the plant extracts were determined by qualitative phytochemical analysis, HPLC analysis and GC-TOFMS analysis. The results from the phytochemical analysis indicated the presence of saponin, anthroquinone, flavonoid, tan
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Gu, Shaobin, Ying Wu, and Jianbo Yang. "Screening of cytoprotectors against methotrexate-induced cytogenotoxicity from bioactive phytochemicals." PeerJ 4 (May 11, 2016): e1983. http://dx.doi.org/10.7717/peerj.1983.

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As a well known anti-neoplastic drug, the cytogenotoxicity of methotrexate (MTX) has received more attention in recent years. To develop a new cytoprotector to reduce the risk of second cancers caused by methotrexate, an umu test combined with a micronucleus assay was employed to estimate the cytoprotective effects of ten kinds of bioactive phytochemicals and their combinations. The results showed that allicin, proanthocyanidins, polyphenols, eleutherosides and isoflavones had higher antimutagenic activities than other phytochemicals. At the highest dose tested, the MTX genetoxicity was suppre
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Gaol, Agnes Della Lumban, and Sujarwati. "Phytochemical Profiling of Tampoi (Baccaurea macrocarpa (Miq.) Mull. Arg.) Leaves Using Liquid Chromatography-Tandem Mass Spectrometry." Jurnal Biologi Tropis 25, no. 3 (2025): 2577–83. https://doi.org/10.29303/jbt.v25i3.8964.

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Tampoi leaves (Baccaurea macrocarpa (Miq.) Mull. Arg.) have been reported to contain a diverse array of phytochemicals associated with various biological activities, including antioxidant and antibacterial effects, as well as the enhancement of erythrocyte and hemoglobin levels in anemic mouse models. This study aimed to comprehensively characterize the phytochemical profile of tampoi leaves to establish a foundation for elucidating the mechanisms underlying their biological activities. Extraction was conducted using a solid phase method with methanol as the solvent. Phytochemical profiling wa
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Abdullahi, Sharif Alhassan, Ngah Zasmy Unyah, Noshariza Nordin, et al. "Phytochemicals and Potential Therapeutic Targets on Toxoplasma gondii Parasite." Mini-Reviews in Medicinal Chemistry 20, no. 9 (2020): 739–53. http://dx.doi.org/10.2174/1389557519666191029105736.

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Identification of drug target in protozoan T. gondii is an important step in the development of chemotherapeutic agents. Likewise, exploring phytochemical compounds effective against the parasite can lead to the development of new drug agent that can be useful for prophylaxis and treatment of toxoplasmosis. In this review, we searched for the relevant literature on the herbs that were tested against T. gondii either in vitro or in vivo, as well as different phytochemicals and their potential activities on T. gondii. Potential activities of major phytochemicals, such as alkaloid, flavonoid, ter
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H, Shahzad. "Antioxidants from Bauhinia and Future Research Gap." Annals of Experimental and Molecular Biology 5, no. 1 (2023): 1–8. http://dx.doi.org/10.23880/aemb-16000118.

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Flower buds of Bauhinia are utilized as a human means of nourishment, and the stem and leaves serve as feed for livestock across the world. This chapter highlights the medicinal importance of various parts of Bauhinia plants. Bauhinia plants’ edible regions are an excellent source of phytochemicals that have notable potential as antioxidants. Various phytochemical compounds that include Saponins, glycosides (kaempferol-3-glucoside), cardiac glycosides, sterols (β-sitosterol), tannins, phenolics, alkaloids, terpenoids (Lupeol), quinones, flavanones and flavonoids reside in these plants. These p
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Usmani Rana, Hafiza Maria, Haseeb Nisar, Jignesh Prajapati, et al. "Integrative bioinformatic analysis to identify potential phytochemical candidates for glioblastoma." Heliyon 10, no. 24 (2024): e40744. https://doi.org/10.1016/j.heliyon.2024.e40744.

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Jahangeer, Muhammad, Ghulam Mustafa, Naveed Munir, Sibtain Ahmed, and Khalid Mashai Al-Anazi. "Exploring the Potential of Plant Bioactive Compounds against Male Infertility: An In Silico and In Vivo Study." Molecules 28, no. 23 (2023): 7693. http://dx.doi.org/10.3390/molecules28237693.

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Infertility is a well-recognized multifactorial problem affecting the majority of people who struggle with infertility issues. In recent times, among infertility cases, the male factor has acquired importance, and now it contributes to approximately half of the infertility cases because of different abnormalities. In the current study, we used natural phytochemicals as potential drug-lead compounds to target different receptor proteins that are involved in the onset of male infertility. A set of 210 plant phytochemicals were docked counter to active site residues of sex hormone-binding globuli
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Dissertations / Theses on the topic "PHYTOCHEMICAL CANDIDATES"

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YADAV, SWATI. "IDENTIFICATION OF POTENTIAL PHYTOCHEMICAL CANDIDATES FOR INHIBITION OF NLRP3 INFLAMMASOME IN DCM : AN IN-SILICO STUDY." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/20270.

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One of the most prevalent adverse consequences of diabetes is diabetic cardiomyopathy (DCM), which is also the leading cause of death in people with diabetes. This disease was discovered in 1972 and has been the subject of research ever since. Over the past ten years, extensive research has been done on the pathophysiology and clinical characteristics of diabetic cardiomyopathy, but there are currently few proven methods for its prevention and treatment. Basically, DCM occurs because of the unregulated metabolic pathways associated with diabetes, which further result in high oxidative stress a
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Book chapters on the topic "PHYTOCHEMICAL CANDIDATES"

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Joy, Christy, and Marria C. Cyriac. "Phytochemicals as Potential Drug Candidates for SARS Cov-2: An RDRp Based In-Silico Drug Designing." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_7.

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AbstractThe global pandemic that the world is currently witnessing, COVID-19, even with vaccines available, the test positivity rate (TPR) tends to remain highly threatening. This research focuses on identifying phytochemicals, previously known for their broad-spectrum antiviral properties which can be potential drug candidates for theSARS-CoV-2. A total of 225 phytocompounds (downloaded from PubChem database) are docked against targetprotein (downloaded from PDB database) of SARS-CoV-2using the POAP pipeline. The target protein is the RDRp complex. They are screened according to their binding
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Li, Han-bing, Yuan-hai Sun, Teng-jiao Zhao, and Sun-ying Cheng. "Phytochemicals as Potential Candidates to Combat Obesity via Non-Shivering Thermogenesis." In Biochemistry of Non-Shivering Thermogenesis in Vertebrates. CRC Press, 2025. https://doi.org/10.1201/9781003391470-17.

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Azeem, Kashish, Iram Irfan, Mohd Shakir, Diwan S. Rawat, and Mohammad Abid. "Therapeutic Potential of Phytochemicals and Their Derivatives as Antifungal Candidates: Recent Discovery and Development." In Advances in Antifungal Drug Development. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-5165-5_19.

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Gürbüz Çolak, Nergiz. "Phytochemicals: Potential Drug Candidates for Leishmaniasis." In Recent Advances in Phytochemical Research [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1007961.

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Leishmaniasis is a neglected tropical disease with three main clinical manifestations. This disease is caused by protozoan parasites that are transmitted through the bite of female sandflies. Each year, more than one million cases of leishmaniasis are reported, and over one billion people are at risk of contacting the disease. Leishmaniasis is a complex disease that relapses when the immune system is suppressed. The currently available antileishmanial drugs have serious side effects. Therefore, it is important to identify novel drug candidates for leishmaniasis treatment. Phytochemicals are pr
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Sánchez-Martínez, Víctor Alberto, Sandra Jazmín Figueroa-Ramírez, Olena Benavides, and Juan Manuel Sierra Grajeda. "Spectroscopic and phytochemical characterization of green corrosion inhibitors from leaves of the Morinda citrifolia plant based on acetone and ethyl acetate." In Sustainable Materials Engineering. ECORFAN, 2024. https://doi.org/10.35429/h.2024.14.1.8.

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Metals suffer corrosion due to the presence of different corrosive media. One way to prevent corrosion is to develop and use corrosion inhibitors that are effective and environmentally friendly. Plant extracts are good candidates because they do not contain toxic substances. In the present work, extracts of Morinda citrifolia leaves were obtained and characterized in acetone and ethyl acetate. The extracts were obtained by maceration for 72 hours. Subsequently, they were characterized by spectroscopic and phytochemical techniques. The spectroscopic techniques showed the presence of anthocyanin
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Acikalin Coskun, Kubra, Merve Tutar, Elif Cansu Abay, Nazlican Yurekli, Mervenur Al, and Yusuf Tutar. "Drugs and Drug Candidates for the Treatment of Lymphoma." In Lymphoma. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103705.

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Cancer is the biggest health problem worldwide due to its high mortality rate. Lymphoma is defined as a group of malignant diseases that is caused by clonal proliferation of lymphocytes and is classified under two major groups: Hodgkin lymphoma and non-Hodgkin lymphoma. Genetic predisposition and some environmental factors constitute risk factors. Symptoms of the disease include unexplained fever, swelling of lymph glands, swollen abdomen, tiredness, loss of appetite, frequent infections, and weight loss. Positron emission tomography (PET) and computed tomography (CT) scans, along with MRI, ar
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Maru, Harshnad, Kanchan Sharma, Saurav Kumar Mishra, and Georrge John J. "A Comprehensive Review of Ethnomedical Uses, Phytochemical Studies, and Properties of Holy Basil (Ocimum sanctum Linn.)." In Pharmacological Benefits of Natural Agents. IGI Global, 2023. http://dx.doi.org/10.4018/978-1-6684-6737-4.ch004.

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Environment-derived products such as secondary metabolites from plants and animals also provide a humongous chemical space for potential candidates for drug discovery. It is a known fact that over 80% of the approved drugs have either been derived or are directly used in natural products. Ocimum sanctum L. or holy basil has been considered a majestic reservoir for medically potential phytochemicals and tremendous therapeutic applications. Basil was the most widely used medicinal plant in ancient civilizations in Africa, Central and South America, and Middle Eastern countries of Asia such as In
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Mzioud, Khaoula, Nouhaila Ferraa, Zakia Aribou, et al. "Green Corrosion Protection." In Advances in Chemical and Materials Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-6341-6.ch008.

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Metal corrosion poses a significant threat to environmental integrity and human safety, necessitating the exploration of alternatives to conventional corrosion inhibitors known for their adverse environmental and health impacts. In response to this imperative, natural plant extracts have emerged as promising candidates for eco-friendly corrosion inhibition. With their rich phytochemical composition and inherent affinity for metal surfaces, these extracts demonstrate considerable efficacy in preventing corrosion. Moreover, their potential incorporation into coating formulations offers enhanced
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Oluwasegun Samson, Awotunde, Omogbadegun Olu Richard, and Mugambwa Joseph Yusuf. "Spirulina: A Living Library of Anticancer Phytochemicals." In Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815124699123010013.

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Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. It is one of the major causes of human death, especially in developing countries. Alternative cancer treatments using medicinal plants are exploited because plants produce phytochemical compounds, which are secondary metabolites used for natural defence but could also be useful in inhibiting cancer growth. Medicinal plants also have limited side effects and toxicity as compared to conventional chemotherapy and irradiation treatments. Hence there is a need to develop n
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Bicak, Bilge, and Serda Kecel Gunduz. "Computer-Aided Drug Design of Plant-Based Compounds." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-7337-5.ch013.

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Non-nutritive phytochemicals found in plants have a protective effect on health and contain various compounds for the prevention and treatment of various diseases. For these compounds, drug candidate studies of plant-based compounds can be carried out with various methods and techniques. Drug design and discovery is a very complex and expensive process, and nowadays, drug discovery studies are supported by computer-aided drug design. The important point in computer-based drug design is a good understanding of the molecular structure of drug candidates. Various theoretical and computational app
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Conference papers on the topic "PHYTOCHEMICAL CANDIDATES"

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Lonika, Charistika, Dono Indarto, and Amelya Augusthina Ayusari. "Roseoside from Lemon Fruits (<i>Citrus limon)</i> as a Potential Inhibitor of Cluster of Differentiation 36 for Obesity Treatment." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-vo3mlu.

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Obesity is a global health problem that prevalence has increased in the last decade. Triglycerides are the main fat component in daily food intake, which can be absorbed directly into the enterocytes through Cluster of Differentiation (CD) 36 transporter protein. Glucagon-like peptide 1 receptor agonist (semaglutide) has recently been approved for obesity treatment, but this medicine has some side effects in the gastrointestinal tract. Administration of Lactobacillus-fermented lemon juice reduced serum triglyceride levels and body weight (BW) of obese rats but it is not related to the action o
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Oguzie, Emeka E. "Evaluation of the Inhibitive Effect of Some Plant Extracts on the Acid Corrosion of Mild Steel." In CORROSION 2010. NACE International, 2010. https://doi.org/10.5006/c2010-10149.

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Abstract The toxicity of most synthetic corrosion inhibitors as well as recent environmental awareness provides sufficient motivation for the evaluation of natural products as potential alternatives. In response to this, the present paper presents the results of a series of studies in our laboratory on the inhibitive effect of selected plant extracts on the acid corrosion of mild steel using different electrochemical and non electrochemical techniques. The results indicate that all the extracts inhibited the corrosion process by virtue of adsorption of their phytochemical constituents on the c
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Hasan, Ziaul, Asimul Islam, and Luqman Ahmad Khan. "Signature Garlic Phytochemical as a Potential Anti-Candidal Candidate Targeting Virulence Factors in Candida albicans." In International Electronic Conference on Biomedicines. MDPI, 2023. http://dx.doi.org/10.3390/ecb2023-14080.

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Reports on the topic "PHYTOCHEMICAL CANDIDATES"

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Takeda, Mamoru. Neurophysiological Mechanisms Underlying the Attenuation of Nociceptive and Pathological Pain by Phytochemicals: Clinical Application as Therapeutic Agents. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.10.02.

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Although phytochemicals are plant-derived toxins that are primarily produced by plants as a form of defense against insects or microbes, several lines of studies have demonstrated that phytochemicals (e.g., polyphenols, carotenoids, and amino acids) have several beneficial biological actions for human health, such as anti-oxidative, anti-inflammatory, and cardioprotective effects. Recent studies have demonstrated that phytochemicals can modulate neuronal excitability in the nervous system, including nociceptive sensory transmission, so it is possible that phytochemicals could be complementary
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Olalekan, Olawale. Exploring Ancient and Alien Cereal Germplasms to Advance Sustainable Wheat Breeding for Enhanced Functional, Nutritional, and Sensory Quality. Faculty of Landscape Architecture, Horticulture and Crop Production Science, Swedish University of Agricultural Sciences, 2024. http://dx.doi.org/10.54612/a.125844vc36.

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Global food security is increasingly threatened by numerous challenges, including widespread malnutrition. Nutritional deficiency, particularly in essential micronutrients such as Zinc (Zn) and Iron (Fe), affects over three billion people worldwide, with pregnant women and children being the most vulnerable. Wheat, as principal cereal crop, provides more than 50% of daily caloric for many populations, contributing essential nutrients such as proteins, vitamins, minerals, and phytochemicals. Wheat’s adaptability to diverse growing conditions and its wide production and consumption make it the m
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