Relevant bibliographies by topics / Piperidine

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Piperidine'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Piperidine"

1

Romero, Nancy, Sylvain Bernès, Luis F. Roa, Joel L. Terán, and Dino Gnecco. "Crystal structures of two chiral piperidine derivatives: 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one and 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione." Acta Crystallographica Section E Crystallographic Communications 71, no. 10 (2015): 1207–11. http://dx.doi.org/10.1107/s2056989015017119.

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The crystal structures of the two title piperidine derivatives show different conformations for the six-membered heterocycle. TheN-substituted 4-piperidinone 1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-4-one, C13H17NO2, (I), has a chair conformation, while the piperidine substituted in position 2 with a thiocarbonyl group, 8-[(1S)-1-phenylethyl]-1,4-dioxa-8-azaspiro[4.5]decane-7-thione, C15H19NO2S, (II), features a half-chair conformation. Comparison of the two structures, and data retrieved from the literature, suggests that the conformational flexibility is mainly related to the hybridization
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Šilhánková, Alexandra, Karel Šindelář, Karel Dobrovský, Ivan Krejčí, Jarmila Hodková, and Zdeněk Polívka. "Synthesis of New L-Proline Amides with Anticonvulsive Effect." Collection of Czechoslovak Chemical Communications 61, no. 7 (1996): 1085–92. http://dx.doi.org/10.1135/cccc19961085.

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Series of heterocyclic L-proline amides were prepared from BOC-L-proline and heterocyclic amines (mostly substituted piperazines and morpholines) via active ester with hydroxysuccinimide. 4-(4-Fluorobenzoyl)piperidine afforded L-proline 4-(4-(4-(4-fluorobenzoyl)piperidin-1-yl)benzoyl)piperidine (7b) simultaneously with expected L-proline 4-(4-fluorobenzoyl)piperidide (7a). D-Proline N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)amide (2) was prepared starting from D-proline. The amides were tested by methods of biochemical and behavioural pharmacology.
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K, Manjusha R., Shaheen Begum, Arifa Begum, and Bharathi K. "ANTIOXIDANT POTENTIAL OF PIPERIDINE CONTAINING COMPOUNDS-A SHORT REVIEW." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 66. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.26536.

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Piperidine is a saturated heterocyclic ring, considered as a privileged scaffold in view of its role in wide range of biological activities. Piperidine is good candidate molecule for obtaining potent antioxidant agents. The planar nature of this heterocyclic nucleus allows the introduction of substituent groups at different positions on the ring. In the present review, the antioxidant profile of piperidine containing compounds has been focused. The compounds were classified into naturally occurring piperidines, unsaturated piperidines, N-substituted piperidines, piperamides, piperanols, piperi
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Klegraf, Ellen, and Horst Kunz. "Stereoselective Synthesis of 3-Substituted and 3,4-Disubstituted Piperidine und Piperidin-2-one Derivatives." Zeitschrift für Naturforschung B 67, no. 4 (2012): 389–405. http://dx.doi.org/10.1515/znb-2012-0413.

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The stereoselective synthesis of 3-substituted and 3,4-disubstituted piperidine and piperidin-2-one derivatives was achieved starting from 2-pyridone. After N-galactosylation and subsequent O-silylation, nucleophilic addition of organometallic reagents proceeded with high regio- and stereoselectivity at 4-position. Substituents at position 3 were stereoselectively introduced by reaction of electrophiles with amide enolates of the N-galactosyl-2-piperidones.
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Jílek, Jiří, Miroslav Rajšner, Vladimír Valenta, et al. "Synthesis of piperidine derivatives as potential analgetic agents." Collection of Czechoslovak Chemical Communications 55, no. 7 (1990): 1828–53. http://dx.doi.org/10.1135/cccc19901828.

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Reaction of N-(1-(2-phenylethyl)-4-piperidinyl)propionanilide (I) with phosphorus pentasulfide gave the thioamide VI. Acylation of N-(1-(2-phenylethyl)-4-piperidinyl)aniline with 2-(methoxy)acetic and 2-(methylthio)acetic anhydrides afforded the amides II and III. Treatment of 4-anilino-1-benzylpiperidine-4-methanol with thionyl chloride gave the spirocyclic sulfurous acid ester amide XIV. Reduction of the hydrochloride of ethyl 3-(1-ethoxycarbonyl-4-phenylimino-3-piperidinyl)propionate (XXII) with sodium cyanoborohydride gave the perhydro-1,6-naphthyridine derivative XIX, a model compound in
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Guzmán-Rodríguez, Sergio, Jesús Chávez-Reyes, Priscila Vázquez-León, et al. "1-Boc-Piperidine-4-Carboxaldehyde Prevents Binge-Eating Behaviour and Anxiety in Rats." Pharmacology 106, no. 5-6 (2021): 305–15. http://dx.doi.org/10.1159/000513376.

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<b><i>Background:</i></b> Piperidines are biogenic amines studied mainly in toxicology because they were initially found as alkaloids from peppers and insect venoms. Piperidines are also produced in the human body, and their actions seem to be related to wakefulness/sleep and other cognitive phenomena. Piperidines have been minimally characterized for therapeutic applications. In this context, 1-Boc-piperidine-4-carboxaldehyde (1-Boc-piperidine) is a piperidine-derivative molecule with no mechanism of action reported, although its uses include the synthesis of GPR119 se
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Frolov, Nikita A., and Anatoly N. Vereshchagin. "Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications." International Journal of Molecular Sciences 24, no. 3 (2023): 2937. http://dx.doi.org/10.3390/ijms24032937.

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Piperidines are among the most important synthetic fragments for designing drugs and play a significant role in the pharmaceutical industry. Their derivatives are present in more than twenty classes of pharmaceuticals, as well as alkaloids. The current review summarizes recent scientific literature on intra- and intermolecular reactions leading to the formation of various piperidine derivatives: substituted piperidines, spiropiperidines, condensed piperidines, and piperidinones. Moreover, the pharmaceutical applications of synthetic and natural piperidines were covered, as well as the latest s
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Tilve, Santosh, Sandesh Bugde, and Prajesh S.Volvoikar. "Protecting-Group-Directed Regio- and Stereoselective Oxymercuration–Demercuration: Synthesis of Piperidine Alkaloids Containing 1,2- and 1,3-Amino Alcohol Units." Synthesis 50, no. 05 (2017): 1113–22. http://dx.doi.org/10.1055/s-0036-1589523.

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An efficient synthesis of naturally occurring 1,2- and 1,3-amino alcohol unit containing 2-substituted piperidine alkaloids and their analogues has been developed from l-pipecolinic acid. The protocol describes the regio- and stereoselective oxymercuration–demercuration of 2-alkenyl piperidines based on protecting groups to give piperidine alkaloids as a key step.
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Gelbrich, Thomas, Denise Rossi, and Ulrich J. Griesser. "Two polymorphs and the diethylammonium salt of the barbiturate eldoral." Acta Crystallographica Section C Crystal Structure Communications 68, no. 2 (2012): o65—o70. http://dx.doi.org/10.1107/s0108270111055120.

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Polymorph (Ia) of eldoral [5-ethyl-5-(piperidin-1-yl)barbituric acid or 5-ethyl-5-(piperidin-1-yl)-1,3-diazinane-2,4,6-trione], C11H17N3O3, displays a hydrogen-bonded layer structure parallel to (100). The piperidine N atom and the barbiturate carbonyl group in the 2-position are utilized in N—H...N and N—H...O=C hydrogen bonds, respectively. The structure of polymorph (Ib) contains pseudosymmetry elements. The two independent molecules of (Ib) are connectedviaN—H...O=C(4/6-position) and N—H...N(piperidine) hydrogen bonds to give a chain structure in the [100] direction. The hydrogen-bonded la
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Rádl, Stanislav, Wieland Hafner, Petr Hezký, Ivan Krejčí, Jan Proška, and Jan Taimr. "Molecular Modification of Anpirtoline, a Non-Opioid Centrally Acting Analgesic." Collection of Czechoslovak Chemical Communications 64, no. 2 (1999): 363–76. http://dx.doi.org/10.1135/cccc19990363.

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Molecular modification of anpirtoline (2a) is described. Several methods of preparation of 4-[(3-chlorophenyl)sulfanyl]-1-methylpiperidine (3a) and its demethylation led to the deazaanpirtoline (3c). Nucleophilic substitution of piperidine-4-thiole with 2-chloro-4-nitropyridine, 2,4-dichloro-6-methylpyridine, and 3,6-dichloropyridazine led to 2-chloro-4-(piperidin-4-ylsulfanyl)pyridine (6), 4-chloro-6-methyl-2-(piperidin-4-ylsulfanyl)pyridine (7), and 3-chloro-6-(piperidin-4-ylsulfanyl)pyridazine (8), respectively. 2-Chloro-6-(pyridin-4-ylsulfanyl)pyridine (10) and 4-[(2-chloropyridin-6-yl)sul
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Dissertations / Theses on the topic "Piperidine"

1

Lewis, Neil. "Asymmetric piperidine synthesis." Thesis, University of Nottingham, 1995. http://eprints.nottingham.ac.uk/13293/.

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It has been demonstrated that bakers' yeast reduction of 1-tert-butyl-2-methyl 3-oxo-piperidine-1,2-dicarboxylate gives (2R, 3S), 1-tert-butyl-2-methyl 3-hydroxy-piperidine-1,2-dicarboxylate in 80% chemical yield with >99% d.e. and >97% e.e. Also bakers' yeast reduction of 1-tert-butyl-3-ethyl 4-oxo-piperidine-1,3-dicarboxylate gives (3R, 4S), 1-tert-butyl-3-ethyl4-hydroxy-piperidine-1,3-dicarboxylate in 74% chemical yield with >99% d.e. and >93% e.e. The optical purity and absolute configurations of the hydroxy-ester derivatives were determined by conversion into the corresponding chiral bis-
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Taylor, Sarah Alison. "Sulfur-mediated pyrrolidine and piperidine synthesis." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613286.

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Girling, Paul Ricardo. "Novel approaches to piperidine and hydropyridine derivatives." Thesis, Durham University, 2012. http://etheses.dur.ac.uk/6354/.

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Three new modes of reactivity are reported between the reaction of an imine, but-3-en-2-ones and a Lewis acid. These are formal [2+2+2]-, [1+2+1+2]- and [4+2]- cycloadditions, deriving 1,1'-(1,2-dihydropyridine-3,5-diyl)diethanones, 1,1'-(1,4-dihydropyridine-3,5-diyl)diethanones and piperidin-4-ones and respectively. The [2+2+2]- and [1+2+1+2]-cycloadditions proceed when R3 = LG (leaving group), with the [1+2+1+2]-pathway dominating when the imine is easily hydrolysed within the reaction conditions. When R3 ≠ LG, the cycloaddition proceeds through different [4+2]-mechanistic pathways, dependen
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Adams, David Roger. "Studies in the synthesis of piperidine alkaloids." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236570.

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Mosts, R. C. "Studies in the synthesis of piperidine alkaloids." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379495.

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Eskici, Mustafa. "Asymmetric piperidine synthesis via 1,3-cyclic sulfates." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368215.

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Williams, Jodi Thomas. "Stereoselective piperidine synthesis via ene and carbonyl ene cyclisations." Thesis, Oxford Brookes University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289247.

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8

Lenagh-Snow, Gabriel Matthew Jack. "The synthesis of azetidine and piperidine iminosugars from monosaccharides." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:207235d5-2ea5-4724-92fd-924fa0ccd4ed.

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Iminosugars are polyhydroxylated alkaloids, and can be generally defined as sugar mimetics in which the endocyclic oxygen atom has been replaced with a basic nitrogen. A common affect of this atomic substitution is to bestow these compounds with the ability to inhibit various sugarprocessing enzymes; most significantly the glycosidases (glycoside hydrolases) which areintimately involved in a huge array of biological functions. Compounds which inhibit these enzymes concordantly possess much potential as medicinal agents for the treatment of a variety of diseases. Several iminosugars have alread
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Dumare, N. B. "Synthetic studies towards mitralactonine, pipecolic acid and piperidine alkaloids." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2013. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/1920.

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Abdelsalam, Mansour. "Synthesis of piperidines using organometallic chemistry." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/4069/.

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Books on the topic "Piperidine"

1

Rubiralta, Mario. Piperidine: Structure, preparation, reactivity, and synthetic applications of piperidine and its derivatives. Elsevier, 1991.

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Williams, Jodi Thomas. Stereoselective piperidine synthesis via ene and carbonyl ene cyclisations. University of Birmingham, 2003.

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3

Hutchinson, Ian. The synthesis of 3-substituted-2-(nitromethylene)-piperidines. typescript, 1994.

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4

Oetting, Jörg. Optisch aktive [beta]-Hydroxy-carbonsäuren [Beta-Hydroxy-carbonsäuren] als Bausteine für neue Amino-hydroxy-carbonsäuren und Piperidin-Alkaloide: Stereoselektive Totalsynthese von (-)-Cassin. [s.n.], 1995.

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5

C, Heading R., and Wood Jack D, eds. Gastrointestinal dysmotility: Focus on cisapride. Raven Health Care Communications, 1992.

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6

Rubiralta, Mario. Piperidine. Elsevier, 1991.

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7

Vardanyan, Ruben. Piperidine-Based Drug Discovery. Elsevier, 2017.

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Vardanyan, Ruben. Piperidine-Based Drug Discovery. Elsevier, 2017.

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9

Piperidine - Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and its Derivatives. Elsevier, 1991. http://dx.doi.org/10.1016/c2009-0-12882-9.

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Rubiralta, M., E. Giralt, and A. Diez. Piperidine: Structure, Preparation, Reactivity, and Synthetic Applications of Piperidine and Its Derivatives. Elsevier Science & Technology Books, 2013.

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Book chapters on the topic "Piperidine"

1

Gooch, Jan W. "Piperidine." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_8770.

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Lide, David R. "Piperidine." In Handbook of Organic Solvents. CRC Press, 2024. http://dx.doi.org/10.1201/9781003575191-397.

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Howard, Philip H., Gloria W. Sage, William F. Jarvis, and D. Anthony Gray. "Piperidine." In Handbook of Environmental Fate and Exposure Data For Organic Chemicals, Volume II. CRC Press, 2023. http://dx.doi.org/10.1201/9781003418863-58.

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Schomburg, Dietmar, and Dörte Stephan. "Piperidine N-piperoyltransferase." In Enzyme Handbook 11. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_275.

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Wohlfarth, Ch. "Viscosity of piperidine." In Supplement to IV/18. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75486-2_159.

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Demaison, J. "573 C5H11N Piperidine." In Asymmetric Top Molecules. Part 2. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-10400-8_321.

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Wohlfarth, Ch. "Surface tension of piperidine." In Supplement to IV/16. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75508-1_101.

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Li, Jie Jack, and Minmin Yang. "Piperidine, the Enchanted Ring." In Drug Discovery with Privileged Building Blocks. CRC Press, 2021. http://dx.doi.org/10.1201/9781003190806-19.

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Wohlfarth, Christian. "Surface tension of piperidine." In Surface Tension of Pure Liquids and Binary Liquid Mixtures. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-48336-7_91.

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Winkelmann, Jochen. "Self-diffusion coefficient of piperidine." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_138.

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Conference papers on the topic "Piperidine"

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Raman, Aravamudhan. "Green Inhibitors for Coatings and Linings – Traditional vs. Green." In CORROSION 2004. NACE International, 2004. https://doi.org/10.5006/c2004-04410.

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Abstract Pigment additives containing chromates, red lead and excessive zinc, commonly used in olden times in paint systems, are toxic and barred from widespread usage. Use of Cr(III) salts instead of Cr(VI) in conversion coatings has been advocated. Methods have been tried to cover the toxic ingredients by non-toxic topcoats and to make them slow leaching by incorporating them in organometallic pigment form strongly bonded to the polymer base of the coating. Zinc phosphate and other zinc salts are being used instead of chromate salts and these are of the green type and offer excellent inhibit
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Craig, Norman, Alberto Lesarri, Emilio Cocinero, Patricia Ecija, Heinz Rudolph, and Jean Demaison. "EQUILIBRIUM STRUCTURE OF PIPERIDINE." In 69th International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2014. http://dx.doi.org/10.15278/isms.2014.wj12.

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Kovačková, Soňa, Martin Dračínský, and Dominik Rejman. "Piperidine nucleoside phosphonic acid derivatives." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112372.

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Malmakova, A., N. Kystaubayeva, T. Zharkinbek, M. Myrzakhanov, M. Balabekova та V. Yu. "Piperidine-containing phosphonates as immunоcorrectors". У 6TH INTERNATIONAL CONFERENCE ON ENVIRONMENT (ICENV2018): Empowering Environment and Sustainable Engineering Nexus Through Green Technology. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5117135.

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Okeke, Micheal, and Dong-Sheng Yang. "VIBRONIC SPECTRA OF GROUP 13 METAL-PIPERIDINE COMPLEXES." In 2021 International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2021. http://dx.doi.org/10.15278/isms.2021.tl10.

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Muliadi and Muhammad Nurdin. "Terbium piperidine dithiocarbamate with 2.2’ dimethyl-1.10 phenanthroline co-ligand." In 5TH INTERNATIONAL CONFERENCE ON ELECTRICAL, ELECTRONIC, COMMUNICATION AND CONTROL ENGINEERING (ICEECC 2021). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0137981.

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Pereira, M. L. A., L. B. Sousa, T. R. Tomich, F. S. Machado, L. B. Sousa, and L. G. R. Pereira. "Methane mitigation potential of diets supplemented with mesquite piperidine alkaloids for sheep." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_22.

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Pereira, M. L. A., L. B. Sousa, M. M. Campos, A. S. Silva, D. B. Oss, and L. G. R. Pereira. "Potential of diets supplemented with mesquite piperidine alkaloids for sheep: energy use." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_72.

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Sravya, G., N. Bakthavatchala Reddy, and Grigory V. Zyryanov. "Synthesis, structural elucidation and bioassay of morpholine/thiomorpholine and piperidine containing oxazoles." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018089.

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Khalid, Hira. "Synthesis of Bioactive Sulfonamides Bearing Piperidine Nucleus with Talented Activity Against Cholinesterase." In The 16th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2012. http://dx.doi.org/10.3390/ecsoc-16-01064.

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Reports on the topic "Piperidine"

1

Banks, Harold D. Piperidine Synthesis. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada258925.

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Miranda, P. Mechanism of hydrodenitrogenation adsorption of piperidine on reduced molybdenum catalysts. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/7275171.

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Miranda, P. Mechanism of hydrodenitrogenation adsorption of piperidine on reduced molybdenum catalysts. Tenth quarterly report, January 1--March 31, 1992. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/10167178.

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