Relevant bibliographies by topics / Piperidines

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Piperidines'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Piperidines"

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Frolov, Nikita A., and Anatoly N. Vereshchagin. "Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications." International Journal of Molecular Sciences 24, no. 3 (2023): 2937. http://dx.doi.org/10.3390/ijms24032937.

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Piperidines are among the most important synthetic fragments for designing drugs and play a significant role in the pharmaceutical industry. Their derivatives are present in more than twenty classes of pharmaceuticals, as well as alkaloids. The current review summarizes recent scientific literature on intra- and intermolecular reactions leading to the formation of various piperidine derivatives: substituted piperidines, spiropiperidines, condensed piperidines, and piperidinones. Moreover, the pharmaceutical applications of synthetic and natural piperidines were covered, as well as the latest s
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K, Manjusha R., Shaheen Begum, Arifa Begum, and Bharathi K. "ANTIOXIDANT POTENTIAL OF PIPERIDINE CONTAINING COMPOUNDS-A SHORT REVIEW." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 66. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.26536.

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Piperidine is a saturated heterocyclic ring, considered as a privileged scaffold in view of its role in wide range of biological activities. Piperidine is good candidate molecule for obtaining potent antioxidant agents. The planar nature of this heterocyclic nucleus allows the introduction of substituent groups at different positions on the ring. In the present review, the antioxidant profile of piperidine containing compounds has been focused. The compounds were classified into naturally occurring piperidines, unsaturated piperidines, N-substituted piperidines, piperamides, piperanols, piperi
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Talbot, Eric. "Synthesis of Polyfunctionalised 2-Piperidinones Catalysed by Fe(acac)3." Synlett 30, no. 07 (2019): 821–26. http://dx.doi.org/10.1055/s-0037-1610700.

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Herein is reported the synthesis of polyfunctionalised piperidines and 2-piperidinones, through hydrogen atom transfer (HAT) chemistry catalysed by Fe(acac)3. The nature and substitution around the Michael acceptor, as well as the allylic amine, allowed access to all positions of the piperidine ring. The chemistry tolerates a range of different functionalities, allowing the investigation of new and diverse scaffolds.
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Kumar, Ashish, Anamika Sharma, Beatriz G. de la Torre та Fernando Albericio. "Scope and Limitations of γ-Valerolactone (GVL) as a Green Solvent to be Used with Base for Fmoc Removal in Solid Phase Peptide Synthesis". Molecules 24, № 21 (2019): 4004. http://dx.doi.org/10.3390/molecules24214004.

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GVL is a green solvent used in Fmoc-based solid-phase peptide synthesis. It is susceptible to ring opening in the presence of bases such as piperidines, which are used to remove the Fmoc protecting group. Here we studied the formation of the corresponding acyl piperidides by time-dependent monitoring using NMR. The results, corroborated by theoretical calculations, indicate that a solution of piperidines in GVL should be prepared daily for a better Fmoc removal.
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Guzmán-Rodríguez, Sergio, Jesús Chávez-Reyes, Priscila Vázquez-León, et al. "1-Boc-Piperidine-4-Carboxaldehyde Prevents Binge-Eating Behaviour and Anxiety in Rats." Pharmacology 106, no. 5-6 (2021): 305–15. http://dx.doi.org/10.1159/000513376.

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<b><i>Background:</i></b> Piperidines are biogenic amines studied mainly in toxicology because they were initially found as alkaloids from peppers and insect venoms. Piperidines are also produced in the human body, and their actions seem to be related to wakefulness/sleep and other cognitive phenomena. Piperidines have been minimally characterized for therapeutic applications. In this context, 1-Boc-piperidine-4-carboxaldehyde (1-Boc-piperidine) is a piperidine-derivative molecule with no mechanism of action reported, although its uses include the synthesis of GPR119 se
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Möhrle, H., and M. Jeandrée. "Chinazolinderivate durch Cyclodehydrierung von N-(2-substituierten Aryl)-Piperidinen / Quinazoline Derivatives by Cyclodehydrogenation of N-(2-Substituted Aryl)-Piperidines." Zeitschrift für Naturforschung B 54, no. 12 (1999): 1577–88. http://dx.doi.org/10.1515/znb-1999-1217.

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Dehydrogenation of the N-[2-(aminocarbonyl)phenyl]piperidines 1 -5 using Hg(II)-EDTA, generated the quinazolinones 6 -9 . Increasing size of the 4-substituent in the piperidine decreased the oxidation rate and the product yield.N-[2-(Hydroxyiminomethyl)phenyl]piperidines 18-22 showed a different behaviour. While 18 with H g(II)-EDTA in water produced the oxime lactam 24 in quantitative yield, the 4- substituted piperidines 19-21 caused not only a lower reaction rate but also an altered product pattern. The double dehydrogenation to lactams was reduced and the cyclic nitrones, formed by two ele
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Murthy Appala, Venkata Ramana, Kanaka Durga Bhavani Anagani, and Aparna Pasula. "Synthesis of New Piperidine based N(2)-Alkylated 1,2,3-Triazole Hybrids in Basic Medium." Asian Journal of Chemistry 35, no. 1 (2022): 212–16. http://dx.doi.org/10.14233/ajchem.2023.26906.

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The nucleophilic reaction of 1H-triazole derivatives with piperidines under basic conditions is the essential step in the synthesis of a new series of dibenzyl N(2)-C-linked triazolyl piperidines. The triazole derivative was synthesized via the CuAAc reaction of 1-phenylprop-2-yn-1-ol (1a-b) with azidomethyl pivalate. Compound 3a-b underwent dehydroxylation and deprotection reactions using TFA, triethyl silane and 1 M NaOH respectively, yielding monobenzyl 1H-1,2,3-triazole (4a-b). The N(2)-piperidinyltriazoles (6a-j) were synthesized in significant amounts by nucleophilically reacting 1H-tria
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Pelletier, Guillaume, Léa Constantineau-Forget, and André B. Charette. "Directed functionalization of 1,2-dihydropyridines: stereoselective synthesis of 2,6-disubstituted piperidines." Chem. Commun. 50, no. 52 (2014): 6883–85. http://dx.doi.org/10.1039/c4cc02220c.

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A practical and highly stereoselective approach to access 2,6-disubstituted piperidines using an amidine auxiliary is reported. These were reduced to the saturated piperidine rings with high diastereoselectivity.
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Tilve, Santosh, Sandesh Bugde, and Prajesh S.Volvoikar. "Protecting-Group-Directed Regio- and Stereoselective Oxymercuration–Demercuration: Synthesis of Piperidine Alkaloids Containing 1,2- and 1,3-Amino Alcohol Units." Synthesis 50, no. 05 (2017): 1113–22. http://dx.doi.org/10.1055/s-0036-1589523.

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An efficient synthesis of naturally occurring 1,2- and 1,3-amino alcohol unit containing 2-substituted piperidine alkaloids and their analogues has been developed from l-pipecolinic acid. The protocol describes the regio- and stereoselective oxymercuration–demercuration of 2-alkenyl piperidines based on protecting groups to give piperidine alkaloids as a key step.
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Song, Qiao, Sheng Wang, Xiangui Lei, Yan Liu, Xin Wen, and Zhouyu Wang. "One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines." Molecules 27, no. 15 (2022): 4698. http://dx.doi.org/10.3390/molecules27154698.

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Piperidine and pyrrolidine derivatives are important nitrogen heterocyclic structures with a wide range of biological activities. However, reported methods for their construction often face problems of requiring the use of expensive metal catalysts, highly toxic reaction reagents or hazardous reaction conditions. Herein, an efficient route from halogenated amides to piperidines and pyrrolidines was disclosed. In this method, amide activation, reduction of nitrile ions, and intramolecular nucleophilic substitution were integrated in a one-pot reaction. The reaction conditions were mild and no m
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Dissertations / Theses on the topic "Piperidines"

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Turner, Ian. "Piperidines from tetrahydroimidazoles." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334848.

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Adriaenssens, Louis. "Stereoselective synthesis of piperidines." Thesis, Connect to e-thesis to view edited abstract. Move to record for print version, 2008. http://theses.gla.ac.uk/49/.

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Woods, Gordon Alexander. "Synthetic approaches to functionalised piperidines." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:4c6fdb6c-c021-447c-8fc9-35241b552850.

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This thesis is concerned with the synthesis of functionalised piperidines. The piperidine unit is found in numerous alkaloids and other natural products, and has also been incorporated into synthetic compounds of significant therapeutic or strategic synthetic potential. Although numerous syntheses of individual piperidine compounds have been published, there are few general routes to this class of compounds, and there is therefore a need for such routes to be developed. Bicyclic lactams derived from (S)-pyroglutamic acid have been shown to be useful synthons in the synthesis of pyrrolidines. A
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Williams, Meredith Richard Vaughan. "Sulfone-mediated synthesis of enantiopure piperidines." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299202.

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Cariou, Claire. "Diastereoselective synthesis of 2,4,5-trisubstituted piperidines." Thesis, University of Birmingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434701.

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Bergman, Zara Dominique. "2,3,4-trisubstituted piperidines : a stereocontolled approach." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5794/.

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This thesis details a methodology utilising various synthetic pathways towards cyclisation precursors suitable for use in Prins and carbonyl-ene cyclisations to effect 2,3,4-trisubstituted piperidines. Once the precursors were synthesised, we were interested in the stereochemical outcomes of the cyclisations, in particular identity and rational of the kinetic and thermodynamic products and their variation due to differing substituents on C2. Previous work in the Snaith group has addressed various other substitution patterns and 2,3,4-trisubstituted piperidines are central components of a vast
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McGrane, Emma Scott. "Novel approaches towards pyrrolidines and piperidines." Thesis, Kingston University, 2004. http://eprints.kingston.ac.uk/20731/.

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Abdelsalam, Mansour. "Synthesis of piperidines using organometallic chemistry." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/4069/.

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Ferrari, Frank D. "Flexible synthesis of spirocyclic pyrans and piperidines." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3829/.

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Spirocyclic piperidines and spirocyclic pyrans are prevalent throughout nature, often appearing in natural products which exhibit exciting biological activities. Notable examples of spirocyclic piperidine-containing biologically active natural products are halichlorine, pinnaic acid and tauropinnaic acid. Despite their structural similarity, halichlorine and the pinnaic acids were isolated from separate organisms; halichlorine was isolated from extracts of the marine sponge Halichondria okadai while both pinnaic acid and tauropinnaic acid were isolated from the Okinawan bivalve mollusc Pinna m
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Mould, Roger James. "Aza-Wittig rearrangement of aziridines to piperidines." Thesis, University of Exeter, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296237.

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Books on the topic "Piperidines"

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Hutchinson, Ian. The synthesis of 3-substituted-2-(nitromethylene)-piperidines. typescript, 1994.

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Rubiralta, Mario. Piperidine: Structure, preparation, reactivity, and synthetic applications of piperidine and its derivatives. Elsevier, 1991.

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C, Heading R., and Wood Jack D, eds. Gastrointestinal dysmotility: Focus on cisapride. Raven Health Care Communications, 1992.

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James, C. Studies relating to piperidinones. UMIST, 1993.

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Williams, Jodi Thomas. Stereoselective piperidine synthesis via ene and carbonyl ene cyclisations. University of Birmingham, 2003.

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Oetting, Jörg. Optisch aktive [beta]-Hydroxy-carbonsäuren [Beta-Hydroxy-carbonsäuren] als Bausteine für neue Amino-hydroxy-carbonsäuren und Piperidin-Alkaloide: Stereoselektive Totalsynthese von (-)-Cassin. [s.n.], 1995.

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Rubiralta, Mario. Piperidine. Elsevier, 1991.

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8

Poewe, Werner, F. Gerstenbrand, and G. Stern. Clinical Experiences with Budipine in Parkinson Therapy. Springer London, Limited, 2012.

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Vardanyan, Ruben. Piperidine-Based Drug Discovery. Elsevier, 2017.

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Vardanyan, Ruben. Piperidine-Based Drug Discovery. Elsevier, 2017.

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Book chapters on the topic "Piperidines"

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Li, Jie Jack, and Minmin Yang. "Spirocyclic Piperidines." In Drug Discovery with Privileged Building Blocks. CRC Press, 2021. http://dx.doi.org/10.1201/9781003190806-28.

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Quadri, Taiwo W., Nnadozie C. Ebenezer, Lukman O. Olasunkanmi, and Eno E. Ebenso. "Pyridines and Piperidines as Corrosion Inhibitors." In Handbook of Heterocyclic Corrosion Inhibitors. CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-8.

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Mckenna, James. "The Stereochemistry of the Quaternization of Piperidines." In Topics in Stereochemistry. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470147146.ch6.

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Devillers, James, Annick Doucet-Panaye, Jean-Pierre Doucet, Christophe Lagneau, Sébastien Estaran, and André Yébakima. "Predicting Toxicity of Piperidines against Female Adults of Aedes aegypti." In Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases. CRC Press, 2017. http://dx.doi.org/10.4324/9781315151656-11.

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Rajbongshi, Kamal Krishna, Binoyargha Dam, and Bhisma Kumar Patel. "Pyridines, Dihydropyridines and Piperidines: An Outline on Synthesis and Biological Activities." In N-Heterocycles. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0832-3_1.

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Erxleben, Nathan D., Gary S. Kedziora, and Joseph J. Urban. "Anomeric effects in fluoro and trifluoromethyl piperidines: a computational study of conformational preferences and hydration." In Highlights in Theoretical Chemistry. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-48148-6_27.

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Gooch, Jan W. "Piperidine." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_8770.

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Lide, David R. "Piperidine." In Handbook of Organic Solvents. CRC Press, 2024. http://dx.doi.org/10.1201/9781003575191-397.

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Howard, Philip H., Gloria W. Sage, William F. Jarvis, and D. Anthony Gray. "Piperidine." In Handbook of Environmental Fate and Exposure Data For Organic Chemicals, Volume II. CRC Press, 2023. http://dx.doi.org/10.1201/9781003418863-58.

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Schomburg, Dietmar, and Dörte Stephan. "Piperidine N-piperoyltransferase." In Enzyme Handbook 11. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61030-1_275.

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Conference papers on the topic "Piperidines"

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Raman, Aravamudhan. "Green Inhibitors for Coatings and Linings – Traditional vs. Green." In CORROSION 2004. NACE International, 2004. https://doi.org/10.5006/c2004-04410.

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Abstract Pigment additives containing chromates, red lead and excessive zinc, commonly used in olden times in paint systems, are toxic and barred from widespread usage. Use of Cr(III) salts instead of Cr(VI) in conversion coatings has been advocated. Methods have been tried to cover the toxic ingredients by non-toxic topcoats and to make them slow leaching by incorporating them in organometallic pigment form strongly bonded to the polymer base of the coating. Zinc phosphate and other zinc salts are being used instead of chromate salts and these are of the green type and offer excellent inhibit
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Rosset, Isac G., та Antonio C. B. Burtoloso. "Synthesis of Piperidines from Z-α,β-Unsaturated Diazoketones". У 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013915103424.

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Couture, Axel, Eric Deniau, Pierre Grandclaudon, and Stéphane Lebrun. "Synthesis of Cyclic Enehydrazides by Ring-Closure Metathesis. Application to the Enantioselective Synthesis of 2-Alkyl and Aryl Piperidines." In The 10th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01385.

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Craig, Norman, Alberto Lesarri, Emilio Cocinero, Patricia Ecija, Heinz Rudolph, and Jean Demaison. "EQUILIBRIUM STRUCTURE OF PIPERIDINE." In 69th International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2014. http://dx.doi.org/10.15278/isms.2014.wj12.

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Kovačková, Soňa, Martin Dračínský, and Dominik Rejman. "Piperidine nucleoside phosphonic acid derivatives." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112372.

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Malmakova, A., N. Kystaubayeva, T. Zharkinbek, M. Myrzakhanov, M. Balabekova та V. Yu. "Piperidine-containing phosphonates as immunоcorrectors". У 6TH INTERNATIONAL CONFERENCE ON ENVIRONMENT (ICENV2018): Empowering Environment and Sustainable Engineering Nexus Through Green Technology. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5117135.

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Okeke, Micheal, and Dong-Sheng Yang. "VIBRONIC SPECTRA OF GROUP 13 METAL-PIPERIDINE COMPLEXES." In 2021 International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2021. http://dx.doi.org/10.15278/isms.2021.tl10.

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Muliadi and Muhammad Nurdin. "Terbium piperidine dithiocarbamate with 2.2’ dimethyl-1.10 phenanthroline co-ligand." In 5TH INTERNATIONAL CONFERENCE ON ELECTRICAL, ELECTRONIC, COMMUNICATION AND CONTROL ENGINEERING (ICEECC 2021). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0137981.

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Pereira, M. L. A., L. B. Sousa, T. R. Tomich, F. S. Machado, L. B. Sousa, and L. G. R. Pereira. "Methane mitigation potential of diets supplemented with mesquite piperidine alkaloids for sheep." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_22.

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Pereira, M. L. A., L. B. Sousa, M. M. Campos, A. S. Silva, D. B. Oss, and L. G. R. Pereira. "Potential of diets supplemented with mesquite piperidine alkaloids for sheep: energy use." In 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_72.

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Reports on the topic "Piperidines"

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Banks, Harold D. Piperidine Synthesis. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada258925.

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Miranda, P. Mechanism of hydrodenitrogenation adsorption of piperidine on reduced molybdenum catalysts. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/7275171.

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Miranda, P. Mechanism of hydrodenitrogenation adsorption of piperidine on reduced molybdenum catalysts. Tenth quarterly report, January 1--March 31, 1992. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/10167178.

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