Academic literature on the topic 'Platelet glue'

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Journal articles on the topic "Platelet glue"

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Chenna, Deepika, Shamee Shastry, and Soumya Das. "Cocktail Protocol for Preparation of Platelet-Rich Fibrin Glue for Autologous Use." Malaysian Journal of Medical Sciences 28, no. 1 (2021): 35–40. http://dx.doi.org/10.21315/mjms2021.28.1.5.

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Background: Biomaterials containing platelets have been used to promote healing of ulcers and burns, as well as in implantology and maxillofacial and plastic surgery to achieve wound healing and tissue repair. Commercial devices to prepare autologous biomaterials involve diverse preparation methods that can have high production costs and low yields. Hence, we designed a protocol for preparation of large amounts of autologous platelet-rich fibrin (PRF) glue using conventional processing techniques for blood components. Methods: Autologous whole blood collected 72 h before surgery was processed
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Yazawa, Masaki, Hisao Ogata, Tatsuo Nakajima, Taisuke Mori, Naohide Watanabe, and Makoto Handa. "Basic Studies on the Clinical Applications of Platelet-Rich Plasma." Cell Transplantation 12, no. 5 (2003): 509–18. http://dx.doi.org/10.3727/000000003108747073.

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Platelets, which contain many growth factors such as platelet-derived growth factor (PDGF) and transforming growth factor-β (TGF-β), are being used in clinical applications as platelet-rich plasma (PRP). Only a few studies, however, have been conducted on the growth factors present in PRP and on the clinical applications using the drug delivery system (DDS). For the purpose of clinical application, we first modified the PRP preparation method and assessed the amounts of growth factors contained in the human platelet concentrates. Furthermore, we assessed fibrin glue as a DDS of platelet concen
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Xiuwen, Wu, Ren Jianan, Yao Genhong, et al. "Biocompatibility, biodegradation, and neovascularization of human single-unit platelet-rich fibrin glue: an in vivo analysis." Chinese Medical Journal 127, no. 3 (2014): 408–11. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20130412.

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Background The clinical applications of fibrin glue span over several surgical modalities. The aim of this study was to evaluate the biocompatibility and biodegradation of different formulations of platelet-rich fibrin glue in vivo and examine its effects on the neovascularization of wound sites. Methods Human-derived single-unit fibrin glue was prepared. Incisions were made on the backs of rats, and these were coated with homemade glues containing different concentrations of aminomethylbenzoic acid (Groups A-F) or commercial adhesives (Group G). A sham control group was included (Group H). Th
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Tsai, Jui-Che, Shyh Ming Kuo, Shwu Jen Chang, Ioannis Manousakas, and Tim-Mo Chen. "A NOVEL TGD®DEVICE TO GENERATE THERAPEUTIC PLATELET GLUE." Biomedical Engineering: Applications, Basis and Communications 19, no. 04 (2007): 225–29. http://dx.doi.org/10.4015/s1016237207000306.

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The surgical applications of platelet glue (a mixture of platelet gel and fibrin glue) are so far particularly prominent in plastic and orthopedic surgeries. It is shown to accelerate bone fracture and wound healing in many clinical practices. Over the years, one of the components used to prepare platelet glue (PG), thrombin, could only be obtained from pooled human plasma or bovine blood after repeated centrifugation processes. The quantity from this thrombin source is limited and its process deemed time consuming and the risk of infection does exist. Here, we present a stand alone device (TG
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Valbonesi, M., G. Giannini, F. Migliori, R. Dalla Costa, and A. Galli. "The Role of Autologous Fibrin-Platelet Glue in Plastic Surgery: A Preliminary Report." International Journal of Artificial Organs 25, no. 4 (2002): 334–38. http://dx.doi.org/10.1177/039139880202500413.

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To promote wound healing, we used autologous fibrin-platelet glue in 14 patients with skin and soft tissue losses caused by recent trauma or chronic pathology. The level of improvement was scored, arbitrarily, from 0 to 4. Very favourable results (score 3–4) were seen in 11 out of 14 patients. The glue preparation is very easy, inexpensive and creates excellent and stable hemostasis. From a general point of view, we have confirmed the utility of fibrin-platelet glue in terms of reduced infections and length of hospital stay.
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Suzan, Salem, and Saad Islam. "Evaluation of Blood Banked Fibrin Glue versus Blood Banked Platelet Glue as a Local Hemosatic Agent and a Healing Promoter in Patients with Acute Leukemia Undergoing Tooth Extraction." British Journal of Medicine & Medical Research 21, no. 7 (2017): 1–13. https://doi.org/10.9734/BJMMR/2017/33470.

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<strong>Aims: </strong>The purpose of this study was to compare the effectiveness of blood banked platelet glue and blood banked fibrin glue as a local hemostatic agent after tooth extraction in patients diagnosed with acute leukemia with concomitant thrombocytopenia. <strong>Study Design:</strong> Randomized clinical trial. <strong>Place and Duration of Study:</strong> Hematology Unit, Internal Medicine Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt between June 2015 and July 2016. <strong>Methodology:</strong> 21 patients who underwent 60 dental extractions diagnos
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Liang, Min, Zhenzhu Li, Cengceng Gao, Fuping Wang, and Zhongmin Chen. "Preparation and characterization of gelatin/sericin/carboxymethyl chitosan medical tissue glue." Journal of Applied Biomaterials & Functional Materials 16, no. 2 (2017): 97–106. http://dx.doi.org/10.5301/jabfm.5000384.

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Background: The development and application of medical glue has been continuously expanding and advancing. However, there are few glues that combine low-cost with excellent biocompatibility. Methods: We have prepared a medical tissue glue using a gelatin (Gel), sericin (SS) and carboxymethyl chitosan (CMCS) blend solution, cross-linked with 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC). The combination’s characteristics and microstructure morphology were observed by Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). Bond strength tests were used to m
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Norjannah, Siti, Ririn Arminsih Wulandari, and Al Asyary. "Benzene Exposure Analysis through S-Phenylmercapturic Acid in Urine at Platelet Levels in Footwear Workers in Sukajaya Village, Bogor Regency." Open Access Macedonian Journal of Medical Sciences 9, E (2021): 260–64. http://dx.doi.org/10.3889/oamjms.2021.5783.

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BACKGROUND: Benzene is a toxic and carcinogenic compound whose presence in glue is endangering the health of workers in footwear workshops. One of its negative effects is its disruption of the bone marrow, which is where red blood cells, white blood cells, and platelets are produced. AIM: The purpose of this study was to analyze the relationship of benzene exposure with platelet levels in workers through examination of S-phenylmercapturic acid (S-PMA) concentrations in urine. METHODS: The design of the study was cross sectional, with 73 workers used as samples. The concentration of S-PMA was m
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Chen, Tim Mo, Jui-Che Tsai, and Thierry Burnouf. "Cranioplasty Using Osteoconductive Scaffold and Platelet Glue." Journal of Trauma: Injury, Infection, and Critical Care 65, no. 6 (2008): 1321–27. http://dx.doi.org/10.1097/ta.0b013e3181574edf.

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Burnouf, T., C. Y. Su, M. Radosevich, H. Goubran, and M. El-Ekiaby. "Blood-derived biomaterials: fibrin sealant, platelet gel and platelet fibrin glue." ISBT Science Series 4, no. 1 (2009): 136–42. http://dx.doi.org/10.1111/j.1751-2824.2009.01222.x.

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Dissertations / Theses on the topic "Platelet glue"

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Peck, M. Thabit. "The effect of storage time on the platelet concentration of Choukroun's platelet rich fibrin (PRF)." University of the Western Cape, 2011. http://hdl.handle.net/11394/5219.

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Magister Chirurgiae Dentium (MChD)<br>Wound healing is a complex process characterised by the repair and reconstitution of lost or damaged tissue. By the mid 1990s, several methods were proposed to enhance wound healing of surgical sites by introducing high concentrations of human platelets to these areas. In the early 21st century, Choukroun et al (2006b) introduced a new type of platelet concentrate that was devoid of any additives, and required no specialised equipment for its production. This concentrate was termed Platelet-rich fibrin (PRF) and although various aspects of this biomaterial
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Jain, Sandeep. "Use of platelet gel and fibrin glue in the treatment of periodontal intrabony defects." Thesis, Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B37645213.

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Chien, Chian-Shiang, and 簡千翔. "Comparison of platelet-enriched fibrin glue and platelet rich plasma gel biodegradable fibrin scaffolds for tissue engineering of cartilage." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/86903733837355446754.

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碩士<br>臺北醫學大學<br>醫學科學研究所<br>97<br>Articular cartilage has a limited self-regenerative capacity. Tissue engineering using autologous chondrocytes implantation (ACI) provide an promising strategy on cartilage repair, seeding cell on scaffold to culture healthy chondrocytes in vitro, then re-inject into articular cartilage. Platelet-enriched fibrin (PEF) glue are making from autolous platelet rich plasma (PRP). It is a natural materials that has biocompatible and biodegradable properties, can provide 3D environment allow cells do attachment, secretes multiple cytokines for chondrogenesis diffe
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tsung, Lia0 han, and 廖漢聰. "Combination of guided osteogenesis with autologous platelet-rich fibrin glue (PRFG) and mesenchymal stem cell for reconstruction of mandibular defects." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/38747058540196698334.

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碩士<br>長庚大學<br>顱顏口腔醫學研究所<br>95<br>Background: Mandibular bone defects commonly occur after trauma or cancer surgery. These defects are traditionally treated by autologous bone grafts to restore function and aesthetic appearance. However, harvesting autogenous bone grafts is traumatic and is associated with significant donor site morbidity and unpredictable resorption of the bone grafts. Guided tissue regeneration (GTR) and tissue-engineered bone regeneration are potential alternatives. This study examined whether a combination of autologous patelete-rich fibrin glue (PRFG) with mesenchymal ste
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Book chapters on the topic "Platelet glue"

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Cesaro, Simone. "Haemorrhagic Cystitis and Renal Dysfunction." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_51.

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AbstractHaemorrhagic cystitis is a frequent complication after haematopoietic cell transplantation. Supportive measures (analgesics, antispasmodics, blood product transfusions and hyperhydration) are the main mode of treatment, with or without antivirals or experimental approaches (hyperbaric oxygen therapy, fibrin-glue or platelet-rich plasma application, adoptive immunotherapy).
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Takada, Yumiko, Tetsumei Urano, Satomi Takahashi, Kenji Sakakibara, and Akikazu Takada. "Conformational Change of Glu-Plasminogen: Effects of N-Terminal Peptides of Glu-Plasminogen." In Current Aspects of Blood Coagulation, Fibrinolysis, and Platelets. Springer Japan, 1993. http://dx.doi.org/10.1007/978-4-431-68323-0_21.

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Conference papers on the topic "Platelet glue"

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Manabe, S., H. Yanagisawa, S. Ishikawa, et al. "TRYPTOPHAN PYROLYSIS PRODUCTS FOUND IN COOKED FOODS INHIBIT HUMAN PLATELET AGGREGATION BY INHIBITING CYCLOOXYGENASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643402.

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Humans are exposed to numerous toxic compounds in foods. During the past decade, several carcinogenic heterocyclic amines have been reported to be present in the cooked foods. Recently, we reported that some of the carcinogenic heterocyclic amines isolated from foods were present in human plasma. In order to know the effects of the carcinogens isolated from foods on the cell function, we investigated the effects of the carcinogenic heterocyclic amines including Trp-P-1(3-amino-l,4-dimethyl-5H-pyrido❘4,3-b❘indole) and Trp-P-2(3-amino-1-methyl-5H-pyrido❘4,3-b❘indole) on human platelet aggregatio
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Bellucci, S., E. Cambau, B. Candalot, and J. P. Caen. "PHARMACOLOGICAL STUDIES OF PLATELET ANTIAGGREGANTS USING AN IN VITRO MODEL OF PRIMARY HEMOSTASIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643434.

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We used a new device simulating in vitro primary haemostasis : more precisely the reactivity of blood to collagen and ADP. Thus an artificial vessel was created consisting of two main parts : a glass capillary (ID 140 um, length 16 mm, siliconized) simulating the haemodynamic resistance of an arteriole and an aperture (ID 150 um) reflecting the injured part of a cut arteriole. This aperture was performed in a cellulose acetate filter covered with collagen type I (3 mg/ml) to provide a defined surface for the adhesion of platelets and soaked with ADP in a concentration similar to that of injure
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Baker, J. B., M. P. McGrogan, C. Simonsen, R. L. Gronke, and B. W. Festoff. "STRUCTURE AND PROPERTIES OF PROTEASE NEXIN I." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644765.

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Human foreskin fibroblasts secrete several different serine protease inhibitors which differ in size and protease specificities. These proteins, called protease nexins (PNs) all form SDS-resistant complexes with their protease targets. Fibroblast surface receptors recognize the protease-PN complexes and mediate their delivery to lysosomes. PNI is a 45 kilodalton glycoprotein that rapidly inhibits several arg or lys-specific proteases including trypsin, thrombin, and urokinase (k assoc.∼ 4×l06,∼ 6×105 and ∼ 2×105, m−1s−1 respectively). Like antithrombin III, PNI binds heparin and inhibits throm
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Huan, X., Y. Legrand, J. Soria, C. Soria, J. Caen, and J. Fareed. "STUDIES ON THE ANTITHROMBOTIC ACTIONS OF A COLLAGEN PEPTIDE IN A DEFINED MODEL OF VENOUS THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644496.

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The synthesis and biologic actions of a collagen peptide Lys-Pro-Gly-Glu-Pro-Gly-Pro-Lys (CP) were first reported by Fauvel, et. al. in 1979. This peptide was found to inhibit collagen induced aggregation of platelets and to modulate clot formation and specific collagen induced fibrinogen binding by platelets. CP exhibited antithrombotic actions in a modified venous stasis thrombosis model (rabbit) against defined thrombogenic challenges, (ED50;(IV) 0.5 − 2.5 mg/kg; (SC) 2.5 − 7.5 mg/kg). The antithrombotic actions of this peptide exhibited a short half-life (10 minutes) after IV administratio
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Niiya, K., P. Kostel, T. S. Zimmerman, and Z. M. Ruggeri. "CHARACTERIZATION OF A 40 kDa FRAGMENT OF VON WILLEBRAND FACTOR THAT CONTAINS THE GLYCOPROTEIN IIb/IIIa-BINDING DOMAIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642874.

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We have isolated a 40 kDa fragment of von Willebrand factor (vWF) that contains the glycoprotein (GP) Ilb/IIIa-binding domain. The Staphylococcus aureus V8 protease-generated fragment II was digested with trypsin (1:50 enzyme:substrate ratio on a weight-to-weight basis). After addition of a 100fold molar excess of (p-amidinophenyl)methanesulfonyl fluoride in order to inhibit any residual trypsin activity, the whole digest was subjected to ion-exchange and size-exclusion high pressure liquid chromatography. Two major fragments were separated. Analysis by polyacrylamide gel electrophoresis in th
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de Four, N. J., R. M. Bertina, and F. Havgrkate. "STIMULATION OF FIBRINOLYSIS BY ACTIVATED PROTEIN C (APC)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642961.

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In 1960 Mammen and Seegers reported the discovery of a new protein (autoprothrombin II-A, APC) with both anticoagulant and profibrinolytic activity. They found that APC accelerated clot lysis in vitro and proposed that this was due to a reduction of plasmin - inhibitory activity. Many years later Comp et al (J Clin Inv 68: 1221) reported that the infusion of APC into dogs resulted in an increase in circulating plasminogen activator activity. This observation stimulated more extensive studies of the profibrinolytic effects of APC.In our laboratories we have studied the effect of human APC on cl
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