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Journal articles on the topic 'PLMIC'

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Published: 4 June 2021

Last updated: 10 February 2022

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1

N'Diaye, Elsa-Noah, та Eric J. Brown. "The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gβγ". Journal of Cell Biology 163, № 5 (8 грудня 2003): 1157–65. http://dx.doi.org/10.1083/jcb.200307155.

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PLIC-1, a newly described ubiquitin-related protein, inhibited both Jurkat migration toward SDF-1α and A431 wound healing, but the closely related PLIC-2 did not. PLIC-1 prevented the SDF-1α–induced activation of phospholipase C, decreased ligand-induced internalization of SDF-1α receptor CXCR4 and inhibited chemotaxis signaled by a transfected Gi-coupled receptor. However, PLIC-1 had no effect on Gs-mediated adenylyl cyclase activation, and inhibited only the Gβγ-dependent component of Gq-initiated increase in [Ca2+]i, which is consistent with selective inhibition of Gβγ function. PLIC-1 colo

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N'Diaye, Elsa-Noah, Aylin C. Hanyaloglu, Kimberly K. Kajihara, Manojkumar A. Puthenveedu, Ping Wu, Mark von Zastrow, and Eric J. Brown. "The Ubiquitin-like Protein PLIC-2 Is a Negative Regulator of G Protein-coupled Receptor Endocytosis." Molecular Biology of the Cell 19, no. 3 (March 2008): 1252–60. http://dx.doi.org/10.1091/mbc.e07-08-0775.

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The activity of many signaling receptors is regulated by their endocytosis via clathrin-coated pits (CCPs). For G protein-coupled receptors (GPCRs), recruitment of the adaptor protein arrestin to activated receptors is thought to be sufficient to drive GPCR clustering in CCPs and subsequent endocytosis. We have identified an unprecedented role for the ubiquitin-like protein PLIC-2 as a negative regulator of GPCR endocytosis. Protein Linking IAP to Cytoskeleton (PLIC)-2 overexpression delayed ligand-induced endocytosis of two GPCRs: the V2 vasopressin receptor and β-2 adrenergic receptor, witho

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Zhang, Yujiao, Zengyou Li, Juan Gu, Yanke Zhang, Wei Wang, Hui Shen, Guojun Chen, and Xuefeng Wang. "Plic-1, a new target in repressing epileptic seizure by regulation of GABAAR function in patients and a rat model of epilepsy." Clinical Science 129, no. 12 (November 11, 2015): 1207–23. http://dx.doi.org/10.1042/cs20150202.

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Plic-1 regulates GABAAR expression at synaptic sites during epileptic seizure. Plic-1 prolongs the seizure latency and reduces the seizure severity in epileptic rats. Plic-1 affects the inhibitory function by changing the mIPSCs and evoked IPSCs of the phasic GABA-ergic synaptic current.

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Moshel, Yaron A., Robert E. Elliott, David J. Monoky, and Jeffrey H. Wisoff. "Role of diffusion tensor imaging in resection of thalamic juvenile pilocytic astrocytoma." Journal of Neurosurgery: Pediatrics 4, no. 6 (December 2009): 495–505. http://dx.doi.org/10.3171/2009.7.peds09128.

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Object The choice of surgical approach during resection of a thalamic juvenile pilocytic astrocytoma (JPA) is dictated by the location of the displaced normal thalamus and posterior limb of the internal capsule (PLIC). Diffusion tensor (DT) imaging and white matter tractography can identify the location of the PLIC in relation to the tumor and may be useful in planning the operative trajectory. Methods Diffusion tensor imaging was used to localize the PLIC on preoperative MR imaging in 6 children undergoing resection of thalamic JPAs. After review of the standard T2-weighted MR imaging sequenc

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Schipper, Mirjam H., Korné Jellema, Diego Alvarez-Estevez, Johan Verbraecken, and Roselyne M. Rijsman. "Sleep-Related Leg Movements in Patients with Transient Ischemic Attack and Controls." European Neurology 79, no. 3-4 (2018): 171–76. http://dx.doi.org/10.1159/000487666.

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Background: Periodic leg movements during sleep (PLMS) have been associated with an increased risk for cardiovascular diseases and there is a high prevalence of PLMS found in patients with obstructive sleep apnea syndrome (OSAS). We evaluated patients with transient ischemic attack (TIA) for PLMS and respiratory related leg movements (RRLM), versus a control group without TIA. Methods: Twenty-five patients with TIA and 34 patients with no vascular diagnosis were referred for polysomnography. Diagnosis of PLMS was made if the periodic leg movement index (PLMI) was ≥5 and clinical significant as

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Budhiraja, Rohit, Sogol Javaheri, Milena K. Pavlova, Lawrence J. Epstein, Olabimpe Omobomi, and Stuart F. Quan. "Prevalence and correlates of periodic limb movements in OSA and the effect of CPAP therapy." Neurology 94, no. 17 (December 27, 2019): e1820-e1827. http://dx.doi.org/10.1212/wnl.0000000000008844.

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ObjectiveWe sought to assess the prevalence, correlates, and consequences of periodic limb movements of sleep (PLMS) in persons with obstructive sleep apnea (OSA) and the effect (worsening or improvement) of continuous positive airway pressure (CPAP) therapy on PLMS in a large prospective multicenter randomized controlled trial.MethodsWe performed retrospective analyses of data from the Apnea Positive Pressure Long-term Efficacy Study, a prospective multicenter randomized controlled trial. A total of 1,105 persons with OSA enrolled in this study underwent a polysomnographic investigation at ba

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Bailer, Janina, Stefan Feth, Felix Bretschneider, Sabine Rosenfeldt, Markus Drechsler, Volker Abetz, Holger Schmalz, and Andreas Greiner. "Synthesis and self-assembly of biobased poly(limonene carbonate)-block-poly(cyclohexene carbonate) diblock copolymers prepared by sequential ring-opening copolymerization." Green Chemistry 21, no. 9 (2019): 2266–72. http://dx.doi.org/10.1039/c9gc00250b.

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Karubiu, Wilson, Soumendranath Bhakat, Lara McGillewie, and Mahmoud E. S. Soliman. "Flap dynamics of plasmepsin proteases: insight into proposed parameters and molecular dynamics." Molecular BioSystems 11, no. 4 (2015): 1061–66. http://dx.doi.org/10.1039/c4mb00631c.

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Colpani, O., E. Tragni, M. Casula, E. Olmastroni, A. L. Catapano, and P. Magni. "Cardiometabolic profile in PLIC-MI and PLIC-CHIESA cohorts: Comparison of two different geographic settings." Atherosclerosis 315 (December 2020): e182-e183. http://dx.doi.org/10.1016/j.atherosclerosis.2020.10.568.

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Yang, Seung Hyeop, Joon Ki Kim, and Hong Bae Park. "Design of Robust and Non-Fragile Kalman Filter with Polytopic Uncertainties: PLMI Approach." Applied Mechanics and Materials 284-287 (January 2013): 2356–60. http://dx.doi.org/10.4028/www.scientific.net/amm.284-287.2356.

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In this paper, we describe the synthesis of robust and non-fragile Kalman filter design for a class of uncertain linear system with polytopic uncertainties and filter gain variations. The sufficient condition of filter existence, the design method of robust non-fragile filter, and the measure of non-fragility in filter are presented via LMIs(Linear Matrix Inequality) technique. And the obtained sufficient condition can be represented as PLMIs(Parameterized Linear Matrix Inequalities) that is, coefficients of LMIs are functions of a parameter confined to a compact set. Since PLMIs generate infi

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Baragetti, Andrea, Alice Ossoli, Arianna Strazzella, Sara Simonelli, Ivano Baragetti, Liliana Grigore, Fabio Pellegatta, Alberico L. Catapano, Giuseppe Danilo Norata, and Laura Calabresi. "Low Plasma Lecithin: Cholesterol Acyltransferase (LCAT) Concentration Predicts Chronic Kidney Disease." Journal of Clinical Medicine 9, no. 7 (July 18, 2020): 2289. http://dx.doi.org/10.3390/jcm9072289.

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Low high-density lipoprotein-cholesterol (HDL-c) is the most remarkable lipid trait both in mild-to-moderate chronic kidney disease (CKD) patients as well as in advanced renal disease stages, and we have previously shown that reduced lecithin:cholesterol acyltransferase (LCAT) concentration is a major determinant of the low HDL phenotype. In the present study, we test the hypothesis that reduced LCAT concentration in CKD contributes to the progression of renal damage. The study includes two cohorts of subjects selected from the PLIC study: a cohort of 164 patients with CKD (NefroPLIC cohort) a

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Bao, Min, Xianliu Wang, Huihua Yuan, Xiangxin Lou, Qinghua Zhao, and Yanzhong Zhang. "HAp incorporated ultrafine polymeric fibers with shape memory effect for potential use in bone screw hole healing." Journal of Materials Chemistry B 4, no. 31 (2016): 5308–20. http://dx.doi.org/10.1039/c6tb01305h.

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Mangano, Francesco T., Mekibib Altaye, Robert C. McKinstry, Joshua S. Shimony, Stephanie K. Powell, Jannel M. Phillips, Holly Barnard, et al. "Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes." Journal of Neurosurgery: Pediatrics 18, no. 3 (September 2016): 306–19. http://dx.doi.org/10.3171/2016.2.peds15628.

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OBJECTIVE The purpose of this study was to investigate white matter (WM) structural abnormalities using diffusion tensor imaging (DTI) in children with hydrocephalus before CSF diversionary surgery (including ventriculoperitoneal shunt insertion and endoscopic third ventriculostomy) and during the course of recovery after surgery in association with neuropsychological and behavioral outcome. METHODS This prospective study included 54 pediatric patients with congenital hydrocephalus (21 female, 33 male; age range 0.03–194.5 months) who underwent surgery and 64 normal controls (30 female, 34 mal

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Lošťáková, Vladimíra, Milan Kuna, Vítězslav Kolek, Filip Čtvrtlík, and Gabriela Vaculová. "Drug-induced lung injury." Klinická farmakologie a farmacie 32, no. 4 (January 1, 2019): 21–31. http://dx.doi.org/10.36290/far.2018.025.

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Skřičková, Jana, Bohdan Kadlec, and Ondřej Venclíček. "Non-small cell lung cancer." Vnitřní lékařství 63, no. 11 (November 1, 2017): 861–74. http://dx.doi.org/10.36290/vnl.2017.159.

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Hu, Haidai, Ákos Nemecz, Catherine Van Renterghem, Zaineb Fourati, Ludovic Sauguet, Pierre-Jean Corringer, and Marc Delarue. "Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation." Proceedings of the National Academy of Sciences 115, no. 17 (April 9, 2018): E3959—E3968. http://dx.doi.org/10.1073/pnas.1717700115.

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Pentameric ligand-gated ion channels (pLGICs) constitute a widespread class of ion channels, present in archaea, bacteria, and eukaryotes. Upon binding of their agonists in the extracellular domain, the transmembrane pore opens, allowing ions to go through, via a gating mechanism that can be modulated by a number of drugs. Even though high-resolution structural information on pLGICs has increased in a spectacular way in recent years, both in bacterial and in eukaryotic systems, the structure of the open channel conformation of some intensively studied receptors whose structures are known in a

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Hu, Haidai, Rebecca J. Howard, Ugo Bastolla, Erik Lindahl, and Marc Delarue. "Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel." Proceedings of the National Academy of Sciences 117, no. 24 (June 1, 2020): 13437–46. http://dx.doi.org/10.1073/pnas.1922701117.

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Pentameric ligand-gated ion channels (pLGICs) are allosteric receptors that mediate rapid electrochemical signal transduction in the animal nervous system through the opening of an ion pore upon binding of neurotransmitters. Orthologs have been found and characterized in prokaryotes and they display highly similar structure–function relationships to eukaryotic pLGICs; however, they often encode greater architectural diversity involving additional amino-terminal domains (NTDs). Here we report structural, functional, and normal-mode analysis of two conformational states of a multidomain pLGIC, c

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Air, Ellen L., Weihong Yuan, Scott K. Holland, Blaise V. Jones, Karin Bierbrauer, Mekibib Altaye, and Francesco T. Mangano. "Longitudinal comparison of pre- and postoperative diffusion tensor imaging parameters in young children with hydrocephalus." Journal of Neurosurgery: Pediatrics 5, no. 4 (April 2010): 385–91. http://dx.doi.org/10.3171/2009.11.peds09343.

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Object The goal in this study was to compare the integrity of white matter before and after ventriculoperitoneal (VP) shunt insertion by evaluating the anisotropic diffusion properties with the aid of diffusion tensor (DT) imaging in young children with hydrocephalus. Methods The authors retrospectively identified 10 children with hydrocephalus who underwent both pre- and postoperative DT imaging studies. The DT imaging parameters (fractional anisotropy [FA], mean diffusivity, axial diffusivity, and radial diffusivity) were computed and compared longitudinally in the splenium and genu of the c

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Palotai, M., H. L. Weiner, T. Chitnis, J. F. Duffy, and C. R. Guttmann. "1128 Sleep Apnea and Periodic Limb Movements are Highly Prevalent in Patients With Multiple Sclerosis." Sleep 43, Supplement_1 (April 2020): A429—A430. http://dx.doi.org/10.1093/sleep/zsaa056.1122.

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Abstract Introduction The pathogenesis of multiple sclerosis (MS)-related fatigue is multi-factorial, including neurogenic, inflammatory, endocrine, metabolic, mood, as well as sleep disorder-related mechanisms. The confounding effect of sleep disorders on the association between fatigue and neurodegenerative changes in the brain has not been investigated. Our objectives were to assess the prevalence of sleep apnea and periodic limb movements in the framework of a prospective study which investigates the neurogenic causation of treatment-resistant fatigue in MS. Methods MS patients enrolled in

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Chiodo, L., M. Casula, A. L. Catapano, A. Baragetti, K. Garlaschelli, L. Grigore, E. Loggia, et al. "Characterization of metabolic syndrome in PLIC cohort." Nutrition, Metabolism and Cardiovascular Diseases 27, no. 1 (January 2017): e14. http://dx.doi.org/10.1016/j.numecd.2016.11.038.

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Casula, Manuela, Lorenzo Chiodo, Andrea Baragetti, Katia Garlaschelli, Liliana Grigore, Giuseppe Danilo Norata, Fabio Pellegatta, et al. "Characterization of metabolic syndrome in PLIC cohort." Atherosclerosis 263 (August 2017): e181. http://dx.doi.org/10.1016/j.atherosclerosis.2017.06.582.

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Tynchenko, V. S., V. V. Kukartsev, A. I. Cherepanov, V. E. Petrenko, and N. N. Dzhioeva. "Development of PLIC-based time synchronization device." Journal of Physics: Conference Series 1728 (January 2021): 012022. http://dx.doi.org/10.1088/1742-6596/1728/1/012022.

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Rodríguez Garcés, Carlos René, and Johana Andrea Muñoz Soto. "Participación laboral de las mujeres rurales chilenas: tendencias, perfiles y factores predictores." Cuadernos de Desarrollo Rural 12, no. 75 (March 16, 2015): 22. http://dx.doi.org/10.11144/javeriana.cdr12-75.plmc.

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Mediante un Modelo de Regresión Logística se analiza la participación laboral de las mujeres rurales y losfactores asociados. Se observa un aumento en la tasa de participación con reducidos niveles de desempleo,no obstante persistir brechas y precarización de las condiciones de trabajo. Mujeres con mejor preparacióny con actitudes más favorables hacia el trabajo generan ingresos, sostienen familia, desarrollan procesos deempoderamiento. Favorecen la probabilidad de estar empleada: número perceptores de ingreso y de hijos/as, ser jefa de hogar, escolaridad, edad. Son factores inhibidores: tener

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Minárik, Marek. "Molecular profiling of lung cancer." Onkologie 10, no. 1 (March 1, 2016): 7–10. http://dx.doi.org/10.36290/xon.2016.003.

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Koubková, Leona. "Antiangiogenic therapy of lung cancer." Onkologie 12, no. 5 (October 15, 2018): 231–34. http://dx.doi.org/10.36290/xon.2018.042.

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Jakubec, Petr, Monika Žurková, Lenka Hajdová, Aneta Křenková, and Vítězslav Kolek. "The complications after lung transplantation." Vnitřní lékařství 63, no. 11 (November 1, 2017): 848–59. http://dx.doi.org/10.36290/vnl.2017.158.

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Zurutuza, Unai, and Julen Castellano. "Comparación de la respuesta física, en términos absolutos y relativos a la competición, de diferentes demarcaciones en tareas jugadas de fútbol." Cuadernos de Psicología del Deporte 20, no. 1 (December 22, 2019): 190–200. http://dx.doi.org/10.6018/cpd.402291.

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El objetivo fue estudiar las demandas externas absolutas y relativas respecto a la competición de diferentes formatos de juego en el fútbol teniendo en cuenta las diferentes demarcaciones de los jugadores. Se registraron cuatro variables externas en 20 jugadores semiprofesionales en cuatro tipos de tareas jugadas (4vs4 o JRP, 6vs6 o JRM y 8vs8 o JRL) y partidos de entrenamiento (10vs10 o PE) para un total de 467 registros. Las variables externas fueron: la distancia total (DTmin y %DT) y carga del jugador (PLmin y %PL), en valores absolutos por minuto de práctica y en valores relativos al perf

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Saincher, Shaswat, and Jyotirmay Banerjee. "A Redistribution-Based Volume-Preserving PLIC-VOF Technique." Numerical Heat Transfer, Part B: Fundamentals 67, no. 4 (December 10, 2014): 338–62. http://dx.doi.org/10.1080/10407790.2014.950078.

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Gurin, E. I., L. E. Dyatlov, N. N. Konnov, K. V. Popov, and A. V. Sevast'yanov. "A Vernier Time-Interval Measurer on a PLIC." Instruments and Experimental Techniques 47, no. 4 (July 2004): 459–63. http://dx.doi.org/10.1023/b:inet.0000038388.84416.36.

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Aker, Karoline, Ragnhild Støen, Live Eikenes, Miriam Martinez-Biarge, Ingeborg Nakken, Asta Kristine Håberg, Sridhar Gibikote, and Niranjan Thomas. "Therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy in India (THIN study): a randomised controlled trial." Archives of Disease in Childhood - Fetal and Neonatal Edition 105, no. 4 (October 29, 2019): 405–11. http://dx.doi.org/10.1136/archdischild-2019-317311.

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ObjectiveTo evaluate the neuroprotective effect of therapeutic hypothermia (TH) induced by phase changing material (PCM) on MRI biomarkers in infants with hypoxic-ischaemic encephalopathy (HIE) in a low-resource setting.DesignOpen-label randomised controlled trial.SettingOne neonatal intensive care unit in a tertiary care centre in India.Patients50 term/near-term infants admitted within 5 hours after birth with predefined physiological criteria and signs of moderate/severe HIE.InterventionsStandard care (n=25) or standard care plus 72 hours of hypothermia (33.5°C±0.5°C, n=25) induced by PCM.Ma

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Ambroz, Petr, Jana Janoutová, and Vladimír Janout. "Lung Cancer and HPV Infections." Hygiena 61, no. 4 (December 1, 2016): 172–75. http://dx.doi.org/10.21101/hygiena.a1460.

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Pešek, Miloš. "New WHO classification of lung tumours." Onkologie 10, no. 1 (March 1, 2016): 20–24. http://dx.doi.org/10.36290/xon.2016.002.

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Zemanová, Milada. "Advances in radiotherapy for lung cancer." Onkologie 12, no. 4 (September 1, 2018): 155–60. http://dx.doi.org/10.36290/xon.2018.029.

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Kociánová, Jana. "Spirometry - basic examination of the lung function." Vnitřní lékařství 63, no. 11 (November 1, 2017): 889–94. http://dx.doi.org/10.36290/vnl.2017.162.

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Arakaki, Reinaldo Gen Ichiro, and Luiz Antonio Nogueira Lorena. "Uma heurística de localização-alocação (HLA) para problemas de localização de facilidades." Production 16, no. 2 (August 2006): 319–28. http://dx.doi.org/10.1590/s0103-65132006000200011.

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Neste trabalho, foi desenvolvida uma nova heurística de localização-alocação (HLA) para problemas de localização de facilidades (facility). Em tais problemas a questão central é localizar um objeto ou mais objetos, que são chamados de facilidades, e minimizar o custo de localizar estas facilidades. A HLA foi aplicada a dois problemas: o Problema de Localização de Máxima Cobertura (PLMC) e o Problema das P-Medianas Capacitado (PPMC) com o intuito de uma possível integração a Sistemas de Informações Geográficas (SIG). A HLA baseia-se na formação de agrupamentos (clusters) e na possibilidade de m

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Yuan, Weihong, Charles B. Stevenson, Mekibib Altaye, Blaise V. Jones, James Leach, Mykhailo Lovha, Noa Rennert, and Francesco T. Mangano. "Diffusion tensor imaging in children following prenatal myelomeningocele repair and its predictive value for the need and timing of subsequent CSF diversion surgery for hydrocephalus." Journal of Neurosurgery: Pediatrics 27, no. 4 (April 2021): 391–99. http://dx.doi.org/10.3171/2020.9.peds20570.

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OBJECTIVE The aim of this study was to investigate diffusion tensor imaging (DTI), an objective and noninvasive neuroimaging technique, for its potential as an imaging biomarker to predict the need and timing of CSF diversion surgery in patients after prenatal myelomeningocele (MMC) repair. METHODS This was a retrospective analysis of data based on 35 pediatric patients after prenatal MMC repair (gestational age at birth 32.68 ± 3.42 weeks, range 24–38 weeks; 15 females and 20 males). A logistic regression analysis was used to classify patients to determine the need for CSF diversion surgery.

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Tillman, Tommy, Mary H. Cheng, Qiang Chen, Pei Tang, and Yan Xu. "Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics." Biochemical Journal 449, no. 1 (December 7, 2012): 61–68. http://dx.doi.org/10.1042/bj20121072.

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pLGICs (pentameric ligand-gated ion channels) are a family of structurally homologous cation and anion channels involved in neurotransmission. Cation-selective members of the pLGIC family are typically inhibited by general anaesthetics, whereas anion-selective members are potentiated. GLIC is a prokaryotic cation pLGIC and can be inhibited by clinical concentrations of general anaesthetics. The introduction of three mutations, Y221A (Y-3′A), E222P (E-2′P) and N224R (N0′R), at the selectivity filter and one, A237T (A13′T), at the hydrophobic gate, converted GLIC into an anion channel. The mutat

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Heir, Renu, Celine Ablasou, Emilie Dumontier, Meghan Elliott, Christine Fagotto‐Kaufmann, and Fiona K. Bedford. "The UBL domain of PLIC‐1 regulates aggresome formation." EMBO reports 7, no. 12 (November 3, 2006): 1252–58. http://dx.doi.org/10.1038/sj.embor.7400823.

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Mencinger, Jure, and Iztok Žun. "A PLIC–VOF method suited for adaptive moving grids." Journal of Computational Physics 230, no. 3 (February 2011): 644–63. http://dx.doi.org/10.1016/j.jcp.2010.10.010.

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Nahed, Jean, and Joseph Dgheim. "Estimation curvature in PLIC-VOF method for interface advection." Heat and Mass Transfer 56, no. 3 (September 11, 2019): 773–87. http://dx.doi.org/10.1007/s00231-019-02737-4.

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Satheesan, Arun Puliyasserimana, Ashwini R. Chinnappa, Guruprasad Goudar, and Chaitali Raghoji. "Correlation between early magnetic resonance imaging brain abnormalities in term infants with perinatal asphyxia and neuro developmental outcome at one year." International Journal of Contemporary Pediatrics 7, no. 10 (September 21, 2020): 1957. http://dx.doi.org/10.18203/2349-3291.ijcp20204002.

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Background: Hypoxic ischemic encephalopathy is an important cause of permanent brain damage in neonates with perinatal asphyxia. Magnetic resonance imaging (MRI) is valuable in predicting prognosis following HIE.Methods: Prospective observational cohort study was conducted in tertiary level referral hospital in term infants born with perinatal asphyxia. MRI brain was done between 5 to 14 days of age. Anthropometry and neurological examinations were recorded at birth, discharge and follow-up. Denver developmental screening test II was performed at follow up.Results: Out of 174 neonates born wit

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Serranová, Tereza, Matěj Slovák, David Kemlink, Karel Šonka, Mark Hallett, and Evžen Růžička. "Prevalence of restless legs syndrome in functional movement disorders: a case–control study from the Czech Republic." BMJ Open 9, no. 1 (January 2019): e024236. http://dx.doi.org/10.1136/bmjopen-2018-024236.

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ObjectivesThe prevalence of restless legs syndrome (RLS) in functional movement disorders (FMD) is not known. Patients with FMD often present with multiple motor and sensory symptoms. Some of these symptoms might be due to comorbid RLS. Therefore, our objective was to evaluate possible association between FMD and RLS.DesignCase–control study.SettingMovement Disorders Center, 1st Faculty of Medicine and General University Hospital in Prague, Czech Republic.Participants96 consecutive patients with clinically established FMD (80 females, mean age (SD) 45.0 (13) years), and 76 matched controls.Pri

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Barker, Lina, and Maja Tippmann-Peikert. "533 Characteristics of patients with REM sleep without atonia (RSWA)/persistent periodic limb movements of sleep (PLMS) in REM sleep." Sleep 44, Supplement_2 (May 1, 2021): A209—A211. http://dx.doi.org/10.1093/sleep/zsab072.531.

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Abstract Introduction While RSWA in REM sleep behavior disorder (RBD) is associated with male sex, age &gt; 50 years, alpha-synucleinopathies, and narcolepsy, the characteristics of patients with RSWA/PLMS in REM sleep (RSWA/PLMS-REM) without dream enactment behaviors are unexplored. The aim of this study was to compare the demographics, comorbidities and concomitant medication use between RSWA/PLMS-REM patients and non-RSWA/non-PLMS-REM controls. Based on anecdotal clinical observations we hypothesized that these patients are more commonly young, women, have psychiatric or neurological di

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Xing, Qing-Na, Yan-Chao Liu, De-Sheng Xuan, Hong-Lei Shang, Xin Zhao, and Xiao-An Zhang. "Diagnostic Value of Diffusion Tensor Imaging for Infants’ Brain Development Retardation Caused by Pre-Eclampsia." Contrast Media & Molecular Imaging 2021 (July 15, 2021): 1–7. http://dx.doi.org/10.1155/2021/5545178.

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Objective. Pre-eclampsia (PE) can cause brain development delay in infants. This work aims to characterize the pattern differences of brain white matter development in premature infants under PE conditions and those without. Methods. Eighty preterm infants delivered by women with PE were selected as the PE group, and ninety-six preterm infants of the same period born to women without high-risk perinatal factors were used as control. All infants underwent diffusion tensor imaging (DTI) examination. The fractional anisotropy (FA) was measured in five regions of interests (ROIs), including poster

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Mollica, Cristina, and Luca Tardella. "PLMIX: an R package for modelling and clustering partially ranked data." Journal of Statistical Computation and Simulation 90, no. 5 (January 12, 2020): 925–59. http://dx.doi.org/10.1080/00949655.2020.1711909.

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Pešek, Miloš. "Current treatment options for squamous cell carcinoma of the lung." Onkologie 12, no. 4 (September 1, 2018): 161–67. http://dx.doi.org/10.36290/xon.2018.030.

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Špirudová, Lenka, and Jaroslav Nol. "Quality of life of patients after lung transplantation." Kontakt 16, no. 1 (March 21, 2014): e9-e16. http://dx.doi.org/10.1016/j.kontakt.2013.12.002.

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Moraga-Cid, Gustavo, Ludovic Sauguet, Christèle Huon, Laurie Malherbe, Christine Girard-Blanc, Stéphane Petres, Samuel Murail та ін. "Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure". Proceedings of the National Academy of Sciences 112, № 9 (17 лютого 2015): 2865–70. http://dx.doi.org/10.1073/pnas.1417864112.

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The glycine receptor (GlyR) is a pentameric ligand-gated ion channel (pLGIC) mediating inhibitory transmission in the nervous system. Its transmembrane domain (TMD) is the target of allosteric modulators such as general anesthetics and ethanol and is a major locus for hyperekplexic congenital mutations altering the allosteric transitions of activation or desensitization. We previously showed that the TMD of the human α1GlyR could be fused to the extracellular domain of GLIC, a bacterial pLGIC, to form a functional chimera called Lily. Here, we overexpress Lily in Schneider 2 insect cells and s

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Salazar, Hugo, Julen Castellano, and Luka Svilar. "Differences in External Load Variables Between Playing Positions in Elite Basketball Match-Play." Journal of Human Kinetics 75, no. 1 (October 31, 2020): 257–66. http://dx.doi.org/10.2478/hukin-2020-0054.

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Abstract The purpose of this study was to describe the specific demands and structure of interrelationships of external load variables in order to generate a position-related time motion profile in elite basketball. Seventeen professional players from three different playing positions (6 guards, 4 forwards, and 7 centers) were analyzed in five friendly games. Player load per minute (PLmin) was used as an indicator of intensity to compare positions. Furthermore, high and total external variables of jumping (hJUMP and tJUMP), acceleration (hACC and tACC), deceleration (hDEC and tDEC) and change

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Alhmoud, Lina, and Ali Khudhair Al-Jiboory. "Synthesis Conditions for LPV Controller with Input Covariance Constraints." Open Engineering 9, no. 1 (June 4, 2019): 144–50. http://dx.doi.org/10.1515/eng-2019-0018.

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AbstractIn this paper, novel synthesis conditions for state-feedback Linear Parameter Varying (LPV) controller with Input Covariance Constraints (ICC) are developed. The synthesis conditions achieve the following design requirements 1) some constraints need to be satisfied on the control energy and 2) optimizing the performance outputs for the entire parameter space of the LPV system. These conditions are formulated as convex optimization problem with Parameterized Linear Matrix Inequalities (PLMIs) constraints. The effectiveness of the proposed approach is illustrated through numerical exampl

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