Academic literature on the topic 'Plurihormonal Pituitary Adenoma'

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Journal articles on the topic "Plurihormonal Pituitary Adenoma"

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F. El Gharroudi, F. El jaafari, S. Rafi, G. El Mghari, and N. El Ansar. "Pituitary adenoma consecrating GH and ACTH: A rare case report." World Journal of Advanced Research and Reviews 18, no. 1 (2023): 1136–38. http://dx.doi.org/10.30574/wjarr.2023.18.1.0752.

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Plurihormonal Pituitary adenoma is defined as an adenoma that expresses more than one hormone on immunohistochemistry. The most common combination in these adenomas includes growth hormone (GH) and prolactin (PRL). We describe an interesting case of plurihormonal pituitary adenoma with double hormonal staining for adrenocorticotrophic hormone (ACTH) and GH in a patient who presented with acromegaly and subtle signs of Cushing disease due to a large pituitary macroadenoma
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F., El Gharroudi, El jaafari F., Rafi S., El Mghari G., and El Ansar N. "Pituitary adenoma consecrating GH and ACTH: A rare case report." World Journal of Advanced Research and Reviews 18, no. 1 (2023): 1136–38. https://doi.org/10.5281/zenodo.8179191.

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Abstract:
Plurihormonal Pituitary adenoma is defined as an adenoma that expresses more than one hormone on immunohistochemistry. The most common combination in these adenomas includes growth hormone (GH) and prolactin (PRL). We describe an interesting case of plurihormonal pituitary adenoma with double hormonal staining for adrenocorticotrophic hormone (ACTH) and GH in a patient who presented with acromegaly and subtle signs of Cushing disease due to a large pituitary macroadenoma
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Ndong, Charlène-ludwine Bifoume, Sana Rafi, Ghizlane El Mghari, and Nawal El Ansari. "Case Report A Rare Case of Plurihormonal Pituitary Adenoma Associating Cushing's Disease and Silent Prolactinoma." Scholars Journal of Medical Case Reports 10, no. 5 (2022): 422–24. http://dx.doi.org/10.36347/sjmcr.2022.v10i05.001.

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Plurihormonal pituitary adenomas are rare conditions that secrete two or more pituitary hormones. The association of prolactin with other hormones is described but associated with ACTH is uncommon. We report a rare case of mixed adenoma associating Cushing’s disease and silent prolactin adenoma in 21 years old male patient. This case highlights an unusual plurihormonal pituitary adenoma case with a rare association between ACTH and prolactin. It pathogeny is less clearly define.
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Kannan, Subramanian, Susan M. Staugaitis, Robert J. Weil, and Betul Hatipoglu. "A Rare Corticotroph-Secreting Tumor with Coexisting Prolactin and Growth Hormone Staining Cells." Case Reports in Endocrinology 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/529730.

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Pituitary adenomas can express and secrete different hormones. Expression of pituitary hormones in nonneoplastic pituitary cells is regulated by different transcription factors. Some pituitary adenomas show plurihormonal expression. The most commonly reported plurihormonal adenomas are composed of somatotrophs, lactotrophs, thyrotrophs and gonadotrophs. Pituitary adenomas composed of both corticotroph and somatolactotroph secreting cells are not common because transcription factors regulating the expression of these hormones are different. We report a rare case of pituitary adenoma with concom
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Hossain, Alisha, Emily Skutnik, Arjan Ahluwalia, et al. "A Rare Case of a Plurihormonal Pituitary Adenoma." Journal of the Endocrine Society 5, Supplement_1 (2021): A565. http://dx.doi.org/10.1210/jendso/bvab048.1152.

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Abstract Background: Pituitary adenomas are usually benign tumors that arise from adenophypophyseal cells and produce one or two types of hormones. Plurihormonal adenomas are a rare subtype that produce two or more hormones and represent less than 1% of all pituitary adenomas. Clinical Presentation: A 76-year-old female presented for evaluation of abnormal thyroid function test results. She was found to have an elevated free T4 of 1.92 ng/dL and total T4 of 14.4 ug/dL with an inappropriately normal TSH of 2.11 uIU/mL. Physical examination was significant for tachycardia, tremors, diaphoresis,
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Amir, Jumana, Marie Christine Guiot, and Natasha Garfield. "Plurihormonal pituitary adenoma cosecreting ACTH and GH: a rare cause of Cushing’s disease." BMJ Case Reports 15, no. 11 (2022): e251451. http://dx.doi.org/10.1136/bcr-2022-251451.

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Plurihormonal pituitary adenomas are rare forms of pituitary adenomas that express more than one hormone. The most common association is with growth hormone (GH) and prolactin. Cosecretion of GH and adrenocorticotrophic hormone (ACTH) is rare with only 25 reported cases in literature. Most presented with features of GH excess, and only four presented with Cushing’s disease. We report a case of a woman in her 30s with recurrent plurihormonal pituitary macroadenoma cosecreting GH and ACTH, diagnosed during workup for polycystic ovarian syndrome, and both times presenting uniquely with Cushing’s
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Vora, TarangK, and Sudish Karunakaran. "Thyrotropic pituitary adenoma with plurihormonal immunoreactivity." Neurology India 65, no. 5 (2017): 1162. http://dx.doi.org/10.4103/neuroindia.ni_577_16.

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CAMARA, M'BALLOU, SANA RAFI, MGHARI GHIZLANE El, and ANSARI NAWAL El. "Mixed corticotropic and somatotropic pituitary adenoma: A case report." World Journal of Advanced Research and Reviews 17, no. 2 (2023): 735–38. https://doi.org/10.5281/zenodo.8109595.

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Multi-secreting pituitary adenomas are relatively rare. The mixed somatotropic and corticotropic pituitary adenoma is very rare. The most widely described association is that coupling hypersecretion of GH and prolactin. We report the case of a patient with a pituitary adenoma bi-secreting GH and ACTH. He was a 28-year-old patient admitted for pituitary tumor syndrome, cushing syndrome. The hormonal assessment found a dependent ACTH cushing syndrome. The other hypothalamohypophysial axes were without abnormality. The hypothesis of a pituitary adenoma was raised. The brain scan confirmed the dia
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Buurman, Hilke, and Wolfgang Saeger. "Subclinical adenomas in postmortem pituitaries: classification and correlations to clinical data." European Journal of Endocrinology 154, no. 5 (2006): 753–58. http://dx.doi.org/10.1530/eje.1.02107.

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Objective: The aim of this study was to examine pituitary adenomas in a series of postmortem pituitaries by use of modern technologies of immunostaining, to classify the adenomas according to the current WHO classification and to analyse the possible associations to the available clinical data. Methods: In this study, pituitaries of 3048 autopsy cases obtained from autopsy series of the years 1991–2004 were examined. Results: A total of 334 pituitary adenomas were found in 316 pituitaries. One hundred and thirty-two sparsely granulated prolactin cell adenomas (39.5%), 75 null cell adenomas (22
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Bovenkamp, Daniela, Alexander Micko, Jeremias Püls, et al. "Line Scan Raman Microspectroscopy for Label-Free Diagnosis of Human Pituitary Biopsies." Molecules 24, no. 19 (2019): 3577. http://dx.doi.org/10.3390/molecules24193577.

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Pituitary adenomas are neoplasia of the anterior pituitary gland and can be subdivided into hormone-producing tumors (lactotroph, corticotroph, gonadotroph, somatotroph, thyreotroph or plurihormonal) and hormone-inactive tumors (silent or null cell adenomas) based on their hormonal status. We therefore developed a line scan Raman microspectroscopy (LSRM) system to detect, discriminate and hyperspectrally visualize pituitary gland from pituitary adenomas based on molecular differences. By applying principal component analysis followed by a k-nearest neighbor algorithm, specific hormone states w
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Book chapters on the topic "Plurihormonal Pituitary Adenoma"

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McCormack, Ann. "Pituitary Carcinoma." In Oxford Textbook of Endocrinology and Diabetes 3e, edited by John A. H. Wass, Wiebke Arlt, and Robert K. Semple. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198870197.003.0029.

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Pituitary carcinomas (PC) are very rare, comprising just 0.2% of all pituitary tumours, but have a high mortality rate. Diagnosis of PC requires the documentation of craniospinal or systemic metastases. PC are thought to arise from a multistep genetic progression from a benign pituitary tumour. Certain subtypes of pituitary adenoma, such as silent corticotroph adenoma and plurihormonal PIT-1 positive adenomas, present a higher risk of aggressive behaviour. Clinical features such as the emergence of resistance to medical therapy or rapid tumour growth may also herald malignant transformation. P
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