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1

Mota, Marcelo de Andrade. "Avaliação das ações de prevenção e vigilância à influenza aviária, desenvolvidas pelo Programa Nacional de Sanidade Avícola PNSA, no período de 2004 a 2007." Universidade Federal de Minas Gerais, 2012. http://hdl.handle.net/1843/BUOS-8YVLSW.

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Brazil has established itself as world's largest exporter of chicken meat since 2000. To ensure health status and the maintenance of the international Brazilian poultry markets it was organized official AI surveillance strategies. Between 2004 and 2005, it monitored1,064 municipalities in commercial poultry production, located in 14 Brazilian states. It was collected 106,226 sera and 7,017 tracheal and cloacae swabs. GIS was used to visualize the distribution of serological results. One epidemiological cluster was identified, located in Rondônia State, obtained after interpolation of ELISA pos
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Abel, Guy, Bilal Barakat, Samir KC, and Wolfgang Lutz. "Meeting the sustainable development goals leads to lower world population growth." The National Academies of Sciences, Engineering, and Medicine, 2016. http://dx.doi.org/10.1073/pnas.1611386113.

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Here we show the extent to which the expected world population growth could be lowered by successfully implementing the recently agreed-upon Sustainable Development Goals (SDGs). The SDGs include specific quantitative targets on mortality, reproductive health, and education for all girls by 2030, measures that will directly and indirectly affect future demographic trends. Based on a multidimensional model of population dynamics that stratifies national populations by age, sex, and level of education with educational fertility and mortality differentials, we translate these goals into SDG popul
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3

Kebede, Endale Birhanu, Wolfgang Lutz, Cuaresma Jesus Crespo, and Alexia Fürnkranz-Prskawetz. "Education rather than age structure brings demographic dividend." The National Academies of Sciences, Engineering, and Medicine, 2019. http://dx.doi.org/10.1073/pnas.1820362116.

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The relationship between population changes and economic growth has been debated since Malthus. Initially focusing on population growth, the notion of demographic dividend has shifted the attention to changes in age structures with an assumed window of opportunity that opens when falling birth rates lead to a relatively higher proportion of the working-age population. This has become the dominant paradigm in the field of population and development, and an advocacy tool for highlighting the benefits of family planning and fertility decline. While this view acknowledges that the dividend can onl
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Kebede, Endale Birhanu, Anne Goujon, and Wolfgang Lutz. "Stalls in Africa's fertility decline partly result from disruptions in female education." The National Academies of Sciences, Engineering, and Medicine, 2019. http://dx.doi.org/10.1073/pnas.1717288116.

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Population projections for sub-Saharan Africa have, over the past decade, been corrected upwards because in a number of countries, the earlier declining trends in fertility stalled around 2000. While most studies so far have focused on economic, political, or other factors around 2000, here we suggest that in addition to those period effects, the phenomenon also matched up with disruptions in the cohort trends of educational attainment of women after the postindependence economic and political turmoil. Disruptions likely resulted in a higher proportion of poorly educated women of chil
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Lutz, Wolfgang, Cuaresma Jesus Crespo, Endale Birhanu Kebede, Alexia Fürnkranz-Prskawetz, Warren Sanderson, and Erich Striessnig. "Education rather than age structure brings demographic dividend." The National Academies of Sciences, Engineering, and Medicine, 2019. http://dx.doi.org/10.1073/pnas.1820362116.

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The relationship between population changes and economic growth has been debated since Malthus. Initially focusing on population growth, the notion of demographic dividend has shifted the attention to changes in age structures with an assumed window of opportunity that opens when falling birth rates lead to a relatively higher proportion of the working-age population. This has become the dominant paradigm in the field of population and development, and an advocacy tool for highlighting the benefits of family planning and fertility decline. While this view acknowledges that the dividend
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6

Siqueira, Tauana Almeida. "Contribuição do PNMA I, PNMA II e do PPG7 para o fortalecimento das instituições ambientais no Brasil." reponame:Repositório Institucional da UnB, 2006. http://repositorio.unb.br/handle/10482/2586.

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Dissertação (mestrado)—Universidade de Brasília, Centro de Desenvolvimento Sustentável, 2006.<br>Submitted by wesley oliveira leite (leite.wesley@yahoo.com.br) on 2009-11-25T15:43:13Z No. of bitstreams: 1 Tauana Almeida Siqueira.pdf: 257026 bytes, checksum: 4a59b8a1790eb10d356da03bb448e2fe (MD5)<br>Approved for entry into archive by Joanita Pereira(joanita) on 2009-12-07T17:26:26Z (GMT) No. of bitstreams: 1 Tauana Almeida Siqueira.pdf: 257026 bytes, checksum: 4a59b8a1790eb10d356da03bb448e2fe (MD5)<br>Made available in DSpace on 2009-12-07T17:26:26Z (GMT). No. of bitstreams: 1 Tauana Almei
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Kosgi, S. "Conformationally restricted PNA analogues synthesis and biophysical studies of cationic pyrrolidyl PNA." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2012. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2150.

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8

Tano, Hanna. "PNA-mediated Affibody pretargeting." Thesis, KTH, Skolan för bioteknologi (BIO), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-215031.

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9

Fischbach, Melanie. "Haarnadelförmige PNA-Peptid-Konjugate." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17305.

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Das Entwicklungsstadium bestimmter Krankheiten ist eng mit der Konzentration diverser Proteine in biologischen Proben verknüpft. Eine sensitive Detektion dieser sogenannten Biomarker kann somit maßgeblich zu einer frühzeitigen Diagnose beitragen. In der vorliegenden Arbeit wurden strukturierte, fluorogene Sonden entwickelt, die die Möglichkeit bieten in einem homogenen Verfahren Zielproteine sensitiv, direkt und in Echtzeit nachzuweisen. Die peptidische Erkennungssequenz für das Zielprotein wurde dabei von zwei zueinander komplementären PNA-Segmenten flankiert. Die Sonden besaßen dadurch eine
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10

Cuesta, Seijo Jose Antonio. "Crystallographic studies on echinomycin bisintercalation on DNA and an alternating D-alanyl,L-homoalanyl PNA." Doctoral thesis, [S.l.] : [s.n.], 2005. http://webdoc.sub.gwdg.de/diss/2005/cuesta_seijo.

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Banerjee, A. "Charged peptide nucleic acid analogues: ethano-locked PNA and β-, γ-bisubstituted PNA". Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2014. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2226.

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12

Gogoi, K. "Synthesis and biophysical studies of PNA and chimeric PNA-DNA antisense oligomers with 5 atom linkages." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2007. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2624.

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13

Svensen, Nina. "Cellular analysis and PNA encoded libraries." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/9605.

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A peptide nucleic acid (PNA) encoded 1296 member peptide library was synthesised and incubated with a variety of cell types. Library members entering cells were extracted, hybridised onto DNA microarrays and the peptide identity was determined via deconvolution. Global consensus analysis highlighted the tetrapepide, Glu-Llp- Glu-Glu (Llp is 6-hexamine-N-aminoacetic acid), a surprise in view of the basic residues typically observed in cell penetrating peptides. When evaluated, Glu-Llp- Glu-Glu revealed cellular uptake comparable to a known basic peptide (tetraLlp). In depth delineation via clus
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14

Hradecká, Lucie. "Interní firemní komunikace v holdingu PNS." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-125057.

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This thesis is devoted to internal communications in the holding company PNS. The theoretical part is focused on explaining concepts: communication, internal communication and its tools, methods and barriers. The practical part is focused on the holding PNS and through an anonymous survey analyzes the internal communication and employee views on methods of communication. Based on the results obtained from the survey then evaluate the use of communication tools, efficiency of communication tools and employee satisfaction. The conclusion summarizes the results and proposed some recommendations t
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15

Vitaliani, Roberta. "PNS-EURONETWORK DATABASE: Encefaliti limbiche paraneoplastiche." Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426160.

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Background: Paraneoplastic limbic encephalitis (PLE) has been identified as a separated clinical entity by Corsellis et al. in 1965. It is clinically characterized by short term memory loss, psychiatric symptoms, confusion and seizures. To date there are only two case series with a limited number of patients describing PLE (Gultekin et al., 2000 and Lawn et al 2003). Aims: This European multicenter study was designed to investigate the clinical, oncological and immunological profiles in a larger PLE population and to search for new antibodies targeted towards relevant neuronal antigens. Met
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16

Deyling, Jaime Lauren. "Validation of the PNS-Q-SELF and the PNS-Q-INFORMANT for the Assessment of Insight in Schizophrenia." Cleveland State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1210680875.

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17

Rossi, Nicolo. "Sintesi di PNA a libertà conformazionale ridotta." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7345/.

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The present work started a research project aimed at the synthesis of conformationally “locked” PNA (Peptide Nucleic Acids) monomers. Compared to classic aeg-PNA, this structural modification would result in an improvement in the pairing properties with natural nucleic acids, due to entropic variations in the process. Specifically, an attempt was made to build a PNA monomer around a β-lactam ring. That ring could be imagined as obtained by linking the methylene groups in α position of both the nucleobase and the carboxyl function. These structural properties would imply pre-organization of the
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18

Cottam-Howarth, Barry. "Towards PNA directed chemical total protein synthesis." Thesis, University of Leeds, 2007. http://etheses.whiterose.ac.uk/21098/.

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This thesis is concerned wi.th the development of a novel methodology for the chemical synthesis of proteins. The methodology is expected to overcome limitations of current techniques for chemical synthesis of proteins that restrict the size of the target molecule to less than 150 amino acids. It is intended that the use of a DNA analogue, PNA, as a directing group will allow different short polypeptides to self-assemble into a desired target protein. The first chapter is an overview of literature concerning templated synthesis and the applications of PNA. Examples of simple mctal-templated sy
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Corvaglia, Valentina. "pna - assisted cellular migration on patterned surfaces." Doctoral thesis, Università degli studi di Trieste, 2013. http://hdl.handle.net/10077/8646.

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2011/2012<br>ABSTRACT - The ability to control the cellular microenvironment, such as cell-substrate and cell-cell interactions at the micro- and nanoscale, is important for advances in several fields such as medicine and immunology, biochemistry, biomaterials, and tissue engineering. In order to undergo fundamental biological processes, most mammalian cells must adhere to the underlying extracellular matrix (ECM), eliciting cell adhesion and migration processes that are critical to embryogenesis, angiogenesis, wound healing, tissue repair, and immunity response, to cite few. For instance, upo
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Bregant, Sarah. "Synthèse de thiazolidines fonctionalisées, incorporation dans des PNA et étude des propriétés d'appariement." Paris 6, 2002. http://www.theses.fr/2002PA066397.

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21

Dias, Mariana Marques Dinis. "Prevalência de Listeria mocytogenes em produtos lácteos." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/12253.

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Este relatório descreve a atividade desenvolvida na Autoridade de Segurança Alimentar e Económica (ASAE) durante o estágio curricular do curso de Mestrado Integrado em Medicina Veterinária. Neste período, foram realizadas várias atividades: Elaboração do relatório do Plano Nacional de Colheita de Amostras (PNCA) de 2012, Normativo do PNCA de 2013, Plano Coordenado de DNA de Equino e ações de formação. Com base nos resultados do PNCA realizou-se um estudo sobre “Prevalência de Listeria monocytogenes em produtos lácteos” em Portugal nos anos entre 2009 e 2012. Vários microrganismos podem afetar
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22

Gonçalves, Elinalda José. "Sistema Único de Assistência Social: o desafio Da intersetorialidade na PNAS." Universidade Federal da Paraí­ba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/7220.

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Made available in DSpace on 2015-05-14T13:24:15Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1660243 bytes, checksum: 691a669197785906ba127d33a25574fc (MD5) Previous issue date: 2012-09-28<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>This study aims to analyze the Social Assistance Unique System (SUAS) since its relationship with the model of intersectoral management. We understand the National Social Assistance Programme (PNAS) as a cross-cutting social policy that has the ability to traverse the scope of other social policies, given the complexity of soc
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23

Ma, Zhijie. "Thermodynamics of Metal Binding to Ligand-Modified PNA." Research Showcase @ CMU, 2011. http://repository.cmu.edu/dissertations/35.

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The research in this dissertation is about investigation of steric effect on thestablility of metal-containing peptide nucleic acid (PNA); thermodynamcs of metalbinding to ligand-modified PNA studied by Isothermal titration calorimetry (ITC);incorporation of metal in 2,2’-bipyridine(Bpy) modified PNA triplexes and structuralcharacterization of copper complexed 8-hydroxyquinoline (Q) modified PNA. All theseresearch are necessary to further understand the coordination chemistry in PNAcontext, in comparison with the corresponding coordination of metal and simple ligandfor the construction of hybr
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Kong, Jing. "Applications of Peptide Nucleic Acid (PNA) in Nanotechnology." Research Showcase @ CMU, 2014. http://repository.cmu.edu/dissertations/1039.

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This dissertation is focused on the study of properties of PNA relevant for its use as a new material in nanotechnology applications. More specifically, it describes the synthesis and characterization of a molecular switch based on a ligand-modified PNA, the use of PNA for the sequence-specific functionalization of DNA origami, and the measurement of the rate constant for charge transfer through PNA in solution. Each of these three research projects covers an aspect of PNA relevant to nanotechnology. The molecular switch described in Chapter II is based on a modified PNA that contains two diff
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Yi, Sung Wook. "Cysteine Based PNA (CPNA): Design, Synthesis and Application." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002346.

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26

Scheibe, Christian. "Multivalente Präsentation von Kohlenhydraten via PNA•DNA-Hybridisierung." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16639.

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Die Wechselwirkung zwischen Kohlenhydraten und Lektinen ist relativ schwach. Dennoch ist sie in einer Fülle biologischer Prozesse von essentieller Bedeutung. Eine Verstärkung der Bindungsaffinität wird häufig durch Multivalenz, d. h. die Ausbildung mehrerer Bindungen zwischen zwei Bindungspartnern, realisiert. Neben der reinen Anzahl der präsentierten Liganden spielt jedoch auch deren Positionierung im Raum eine große Rolle. In dieser Arbeit wurde ein molekulares Lineal entwickelt, das einen modular aufgebauten PNA/DNA-Duplex als Gerüst nutzt und die Präsentation von Liganden im Raum mit atoma
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Pasquali, Guilherme Aguiar Mateus. "Uso de carboidrases em dietas à base de milho e farelo de soja para frangos de corte." Botucatu, 2019. http://hdl.handle.net/11449/182179.

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Orientador: Antonio Celso Pezzato<br>Resumo: O uso de enzimas que degradam polissacarídeos não-amiláceos (PNAs) em dietas para monogástricos tem sido cada vez mais explorado por nutricionistas, apesar dos mecanismos pelos quais estas enzimas melhoram o valor nutritivo dos alimentos ainda não estarem totalmente esclarecidos. Assim, este estudo foi desenvolvido com o objetivo de evidenciar os principais mecanismos de ação de enzimas que degradam PNAs e o efeito sobre frangos de corte alimentados com dietas à base de milho e farelo de soja. O primeiro experimento, relatado no Capítulo II, foi des
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Klein, Fernanda Bortolini. "A inclusão produtiva e os desafios para a PNAS e o SUAS." Pontifícia Universidade Católica do Rio Grande do Sul, 2009. http://hdl.handle.net/10923/5173.

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Made available in DSpace on 2013-08-07T19:10:41Z (GMT). No. of bitstreams: 1 000419469-Texto+Completo-0.pdf: 576226 bytes, checksum: 45813acde5e6451478ba73ea4d18caab (MD5) Previous issue date: 2009<br>The production system driven by the productive restructuring led innovation and change as the construction of new forms of organization and working conditions. In front of the aggravation of social problems linked to this logic, many public policies have been directed for seeking the guarantee of the right to work and survival, including the Social Assistance Policy. The study aims to examine h
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Boutimah, Fatima. "Activité antisens de Peptide nucleic acids (PNAs) couplés à des transporteurs peptidiques." Paris 5, 2009. http://www.theses.fr/2009PA05P613.

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Les PNAs ciblant la région codante d’un ARN messager permettent par stratégie antisens de bloquer l’élongation de la traduction. Avant ce travail, seuls les PNAs riches en thymines et capables de former des triplexes avaient été démontrés capables d’une telle activité. Afin d’élargir la variété de séquences ciblées, nous avons montré que des PNAs polypyrimidiques, formant des duplexes ou des triplexes, arrêtent aussi efficacement l’élongation de la traduction. Ces PNAs AS ciblent la séquence polypurine tract du messager de la protéine intégrase du virus VIH-1. Nous avons montré que cette séque
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Mohnani, Stefan. "Synthetic approaches towards modified peptide nucleic acids (PNAs) for biomimetical nanostructured surfaces." Doctoral thesis, Università degli studi di Trieste, 2011. http://hdl.handle.net/10077/4814.

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2009/2010<br>“There is plenty of room at the bottom”. These were the famous words of Richard P. Feynman in 1959 that led to the birth of nanotechnology and nanoscience. Electronic devices based on inorganic semiconductors have been part of our daily lives for the last 60 years. Their miniaturisation has occurred gradually over the years, however, according to Moore’s law the contemporary microelectronic industry’s “top-down” manufacturing technique will soon reach its limits. Therefore, the recent development and increased knowledge of organic semiconductors has led to a tendency to explore al
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Wong, June Tan-Whea. "Functional analysis of semaphorin-1a in the developing PNS." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0019/NQ48738.pdf.

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König, Niclas. "Reconnecting the CNS and PNS with Stem Cell Transplantation." Doctoral thesis, Uppsala universitet, Institutionen för neurovetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-251546.

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Severe injury may result in disconnection between the peripheral and central nervous system. Regeneration of the central portion of sensory neurons into the spinal cord is notoriously poor in adult mammals, with low regenerative drive and an unpermissive central environment, most likely resulting in persistent loss of sensory function. A variety of strategies have been addressedto augment regeneration, including application of growth promoting factors, counteraction of inhibitory molecules, and provision of growth permissive substrates. Stem cells have been investigated in these contexts, as w
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Oyaghire, Stanley. "Recognition of Guanine-quadruplexes by PNA and gammaPNA Oligomers." Research Showcase @ CMU, 2016. http://repository.cmu.edu/dissertations/1030.

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The broad and varying regulatory or causative roles of guanine (G)-quadruplexes in both biological processes and some human diseases incentivize the development of ligands able to recognize these structures and modulate their effects. These reagents might find use either as therapeutics or, more broadly, as discovery probes to elucidate both the existence and functional implications of quadruplex structures in the genome.
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Bamaga, Mohammad Salih. "Pyrazinamide resistance and the pncA gene variability in mycobacterium tuberculosis and related bacteria." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416414.

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Klein, Fernanda Bortolini. "A inclus?o produtiva e os desafios para a PNAS e o SUAS." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2009. http://tede2.pucrs.br/tede2/handle/tede/452.

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Made available in DSpace on 2015-04-14T13:20:14Z (GMT). No. of bitstreams: 1 419469.pdf: 576226 bytes, checksum: 45813acde5e6451478ba73ea4d18caab (MD5) Previous issue date: 2009-12-18<br>O sistema produtivo impulsionado pela reestrutura??o produtiva provocou inova??es e mudan?as como a constru??o de novas formas de organiza??o e condi??es de trabalho. Diante do agravamento da quest?o social ligada ? esta l?gica, muitas pol?ticas p?blicas foram direcionadas para a busca da garantia do direito ao trabalho e a sobreviv?ncia, entre as quais a Pol?tica de Assist?ncia Social. O estudo objetiva ana
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Nunes, Lambiasi Layla. "Sustainable life, not sustainable development - “Other” epistemologies in sanitation policy in Rural Brazil : The case of Brazil’s National Program for Rural Sanitation." Thesis, Linköpings universitet, Institutionen för tema, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-170214.

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Despite decades of global efforts to provide the whole of the world’s population with appropriated water and sanitation, these remain one of the biggest challenges of our time, with the gap being even greater in rural areas. Commonly dominated by technological and managerialist solutions, the field of water and sanitation have been subject, since its origins, to rationalities grounded in western knowledge. As a result, approaches to the topic tends to disregard deeper relationships between the social world and its historical, political, economic and cultural realizations. While many discuss wa
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Prencipe, G. "Newly tailored peptide nucleic acids (PNA) and PNA-modified magnetic nanoparticles for DNA targeting. PEG branched polymer chains functionalization of nano-systems for biocompatibility." Doctoral thesis, Università degli Studi di Milano, 2009. http://hdl.handle.net/2434/180593.

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Abstract 1) Newly tailored peptide nucleic acids (PNA) and PNA-modified magnetic nanoparticles for DNA targeting. 2) PEG branched polymer chains functionalization of nano-systems for biocompatibility. Newly tailored peptide nucleic acids: azaPNA1 Peptide nucleic acid (PNA) is an artificial DNA mimic introduced by Nielsen in 1991, characterized by a pseudopeptide backbone (figure 1) replacing the sugar-phosphate chain. The backbone is made of N-(2-aminoethyl)glycine (aeg) units joint in a polyamide structure, and the purine (A, G) and pyrimidine (C, T) nucleobases are linked to the β-
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Baysal, Gorkem. "Biological Hydrogen Production By Using Co-cultures Of Pns Bacteria." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12615001/index.pdf.

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Biological hydrogen production is a renewable, carbon-neutral and clean route for hydrogen production. Purple non-sulfur (PNS) bacteria have the ability to produce biohydrogen via photofermentation process. The type of the bacterial strain used in photofermentation is known to have an important effect on hydrogen yield. In this study, the effect of different co-cultures of PNS bacteria on photofermentation process was investigated in search of improving the hydrogen yield. For this purpose, growth, hydrogen production and substrate utilization of single and co-cultures of different PNS bacteri
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Gholami, Z. "PNA-protein conjugates for nano-scale modeling of protein aggregates." Thesis, Nottingham Trent University, 2013. http://irep.ntu.ac.uk/id/eprint/54/.

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Programmable assembly of proteins on molecular frameworks requires the development of facile and orthogonal chemical approaches and molecular scaffolds. In this research, the unique characteristics of PNA were applied to create controllable protein assemblies directed by precise PNA-DNA hybridization. The signatures of assembly were studied via FRET, providing a powerful tool which should be effective in live system imaging. Two model systems were developed in this study. In the first model system, site-selective conjugation of monomeric teal fluorescent protein (mTFP) to PNA was achieved by c
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Lonkar, P. S. "Pyrrolidine and piperidine nucleic acids: novel class of PNA analogues." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2004. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2879.

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Castro, Odete José Gouveia de. "Plano nacional de colheitas de amostras (PNCA) - Autoridade de segurança alimentar e económica (ASAE)." Master's thesis, Universidade de Évora, 2010. http://hdl.handle.net/10174/15411.

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O estágio curricular a que se refere o presente relatório teve lugar durante um período de 5 meses, compreendidos de 1 de Outubro de 2009 a 28 de Fevereiro de 2010, na Autoridade de Segurança Alimentar e Económica (ASAE), Lisboa, mais precisamente no Gabinete Técnico e Pericial (GTP - sobretudo no núcleo de Estudos Planeamento da Área Alimentar e no Núcleo de Intervenção Técnica), sob a orientação da Médica Veterinária Dra. Graça Mariano (Directora de Serviços) e da Médica Veterinária Dra. Maria Manuel Mendes. A protecção da saúde e a defesa dos interesses dos consumidores devem ser assegurada
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42

Jarikote, Dilip Venkatrao. "Solid phase synthesis of thiazole orange labeled peptide nucleic acids for homogeneous detection of single base mutation in DNA." Doctoral thesis, [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=983553203.

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Avcioglu, Sevler Gokce. "Scale Up Of Panel Photobioreactors For Hydrogen Production By Pns Bacteria." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612478/index.pdf.

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Production of hydrogen from biomass through the use of dark and photofermentative bacteria will be applicable in the future and a promising route. The aim of this study is to develop and to scale-up solar panel photobioreactors for the biological hydrogen production by photosynthetic purple non sulfur (PNS) bacteria on artificial substrates and on real dark fermentation effluent of molasses. The parameters studied are light intensity, temperature, feed stock, feed rate, pH, cell density, light and dark cycle and carbon to nitrogen ratio on hydrogen production. Continuous hydrogen production ha
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44

Brock, Michele. "Eight-membered PNS heterocycles containing S(IV) and S(VI) centers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ31332.pdf.

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Petersson, Britt. "Structural studies of peptide nucleic acid (PNA) by X-ray crystallography /." Cph. : The Danish University of Pharmaceutical Sciences, Department of Medicinal Chemistry, 2004. http://www.dfh.dk/phd/defences/Brittpetersson.htm.

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Upert, Grégory. "Synthèse et interaction de PNA ciblant l'ARN TAR du VIH-1." Nice, 2007. http://www.theses.fr/2007NICE4104.

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Les médicaments utilisés en polythérapie anti-VIH ciblent des protéines virales (transcriptase inverse, protéase, go41). Ces thérapies ont permis de réduire le taux de mortalité mais génèrent de nombreux effets secondaires et conduisent à l’émergence, parfois très rapide, de souches résistantes aux médicaments utilisés. La recherche de molécules qui agissent sur de nouvelles cibles virales reste donc nécessaire. Une piste consiste à cibler des fragments de l’ARN du VIH qui sont impliqués dans es processus biologiques essentiels à la multiplication virale et dont les séquences sont conservées d
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Noël, Olivier. "Vers la synthèse d’acides nucléiques N-oxy peptidiques et synthèse de ribosondes." Thesis, Cachan, Ecole normale supérieure, 2013. http://www.theses.fr/2013DENS0034.

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Le PNA est un des mîmes d’ADN les plus prometteurs en biologie moléculaire et génomique fonctionnel, pour des applications en tant que biosenseur ou encore dans son utilisation pour du diagnostique et de la détection. Les PNAs sont résistants aux nucléases et aux protéases et s’apparient à leurs complémentaires ADN et ARN selon les règles de Watson Crick, Hoogsteen ou Hoogsteen inverse. Cependant, les PNAs ont une faible solubilité et une pauvre absorption cellulaire qui leurs empêchent d’être utilisés dans des applications thérapeutiques. Différentes modifications ont été apportées pour améli
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Leão, Ricardo de Holanda. "Construção Sócio-Histórica das Configurações Familiares: Uma análise a partir da atuação dos profissionais da Assistência Social no Estado da Paraíba." Universidade Federal da Paraíba, 2016. http://tede.biblioteca.ufpb.br:8080/handle/tede/8521.

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Submitted by Maike Costa (maiksebas@gmail.com) on 2016-08-12T12:00:03Z No. of bitstreams: 1 arquivo total.pdf: 1951383 bytes, checksum: 78b8c51a33df97c47ff485784e336242 (MD5)<br>Made available in DSpace on 2016-08-12T12:00:03Z (GMT). No. of bitstreams: 1 arquivo total.pdf: 1951383 bytes, checksum: 78b8c51a33df97c47ff485784e336242 (MD5) Previous issue date: 2016-05-16<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The Brazilian family passed through inner transformations for centuries, since the Portuguese colonization. Such European influences had become effect
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Aland, G. R. "Aminoethyl-(α,α-dimethyl)-glycyl PNAs: synthesis and interaction studies with DNA and gold nanoparticles". Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2006. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2511.

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Shirude, P. S. "Synthesis and biophysical evaluation of modified and fluorescent PNAs: applications in antisense therapeutics and diagnostics." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2005. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2434.

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