Relevant bibliographies by topics / Potential antagonist

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Potential antagonist'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Potential antagonist"

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Otto-Hanson, L. K., Z. Grabau, C. Rosen, C. E. Salomon, and L. L. Kinkel. "Pathogen Variation and Urea Influence Selection and Success of Streptomyces Mixtures in Biological Control." Phytopathology® 103, no. 1 (2013): 34–42. http://dx.doi.org/10.1094/phyto-06-12-0129-r.

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Success in biological control of plant diseases remains inconsistent in the field. A collection of well-characterized Streptomyces antagonists (n = 19 isolates) was tested for their capacities to inhibit pathogenic Streptomyces scabies (n = 15 isolates). There was significant variation among antagonists in ability to inhibit pathogen isolates and among pathogens in their susceptibility to inhibition. Only one antagonist could inhibit all pathogens, and antagonist–pathogen interactions were highly specific, highlighting the limitations of single-strain inoculum in biological control. However, t
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Nur Aeny, Titik, Radix Suharjo, and Subli Mujim. "SKRINING BAKTERI ANTAGONIS RALSTONIA SP., PENYEBAB PENYAKIT LAYU BAKTERI PISANG DI LAMPUNG." Jurnal Hama dan Penyakit Tumbuhan Tropika 7, no. 2 (2007): 100–110. http://dx.doi.org/10.23960/j.hptt.27100-110.

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Screening on Antagonistic Bacteria of Ralstonia sp., the Causal Agent of Banana Bacterial Wilt in Lampung. This study was conducted on May to October 2006. This study was aimed to screen and collect potential bacterial antagonists toward Ralstonia sp., the causal agent of banana bacterial wilt; to identify the collected potential antagonists, and to test the capability of the bacterial antagonist in vitro. A survey to collect soil samples was conducted in 5 districts in Lampung, namely Bandar Lampung, Lampung Selatan, Tanggamus, Lampung Utara, Lampung Tengah, and Lampung Timur. Identification
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Rojas, C., M. Stathis, J. Alt, et al. "Additional binding mechanism of palonosetron to the 5-HT3 receptor versus first generation 5-HT3 receptor antagonists." Journal of Clinical Oncology 25, no. 18_suppl (2007): 19583. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.19583.

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19583 Background: Palonosetron has a higher binding affinity and longer plasma half-life than first generation 5-HT3 receptor antagonists. Clinical trials have demonstrated that a single intravenous dose of palonosetron 0.25 mg provides better protection from chemotherapy-induced nausea and vomiting than other 5-HT3 receptor antagonists throughout the 5-day post-chemotherapy period. The purpose of this work is to determine differences in the molecular interactions of the antagonists with the receptor that could help explain the clinical efficacy differences. Methods: Molecular ligand-receptor
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C., J., and J. P. "Hormone Antagonist with Broad Potential." Science 245, no. 4924 (1989): 1322. http://dx.doi.org/10.1126/science.245.4924.1322.

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Andriastini, Dewa Ayu, Yan Ramona, and Meitini Wahyuni Proborini. "In Vitro Inhibition of Fungal Antagonists on Fusarium sp., the Disease Causative Agent on Dragon Fruit Plant (Hylocereus undatus (Haw.) Britton & Rose)." Metamorfosa: Journal of Biological Sciences 5, no. 2 (2018): 224. http://dx.doi.org/10.24843/metamorfosa.2018.v05.i02.p14.

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A research on in vitro inhibition of fungal antagonists, isolated from dragon fruit plantation in Sembung village, Bali, on Fusarium sp. (the disease causative agent of dragon fruit plant) was conducted with the main objective to investigate the effectiveness of these fungal antagonists to inhibit the in vitro growth of the pathogen. Dual assay method was applied in this experiment. The results showed that three potential fungal antagonists were successfully isolated in this research and they were identified as Trichoderma harzianum, Aspergillus niger, dan Paecilomyces lilacinus. All these fun
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Maknunah, Jauharoh, and Meity Suradji Sinaga. "Eksplorasi dan Karakterisasi Khamir dan Bakteri sebagai Agens Antagonis terhadap Penyebab Penyakit Blas pada Padi." Jurnal Fitopatologi Indonesia 14, no. 3 (2018): 83. http://dx.doi.org/10.14692/jfi.14.3.83.

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Exploration of Yeasts and Bacteria as Antagonist Agent of Rice Blast PathogenBlast disease (Pyricularia oryzae) is a major disease of rice that causes 61% yield losses. An alternative way to control the disease is applying antagonistic agents, both yeasts and bacteria. This study was aimed to obtain yeast and bacterial isolates that can be used as antagonistic agents to effectively control blast disease. Yeasts and bacteria were isolated from the leaves of Digitaria sp., Panicum sp., and Pennisetum sp.. The isolates of yeasts and bacteria were screened following hypersensitive test on tobacco
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Hogendorf, Agata, Adam S. Hogendorf, Rafał Kurczab, et al. "N-Skatyltryptamines—Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential." Molecules 26, no. 15 (2021): 4605. http://dx.doi.org/10.3390/molecules26154605.

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A series of N-skatyltryptamines was synthesized and their affinities for serotonin and dopamine receptors were determined. Compounds exhibited activity toward 5-HT1A, 5-HT2A, 5-HT6, and D2 receptors. Substitution patterns resulting in affinity/activity switches were identified and studied using homology modeling. Chosen hits were screened to determine their metabolism, permeability, hepatotoxicity, and CYP inhibition. Several D2 receptor antagonists with additional 5-HT6R antagonist and agonist properties were identified. The former combination resembled known antipsychotic agents, while the l
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Rosamilia, A. E., P. A. Mayes, R. Papadopoulos, et al. "Synthesis of Some Nefopam Analogues as Potential Analgesics." Australian Journal of Chemistry 55, no. 9 (2002): 577. http://dx.doi.org/10.1071/ch02097.

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Some derivatives of the non-narcotic analgesic nefopam containing amidine and guanidine substituents have been prepared and their analgesic activity assessed by their ability to block the uptake of noradrenaline. The compounds have been shown to inhibit noradrenaline uptake but they also display possible α1 antagonist activity at higher concentration. An ester derivative was also active and was more selective as it did not exhibit α1 adrenoreceptor antagonism.
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Benveniste, M., J. M. Mienville, E. Sernagor, and M. L. Mayer. "Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons." Journal of Neurophysiology 63, no. 6 (1990): 1373–84. http://dx.doi.org/10.1152/jn.1990.63.6.1373.

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1. Voltage-clamp experiments were used to study N-methyl-D-aspartic acid (NMDA) receptor antagonists applied by fast perfusion to mouse hippocampal neurons in dissociated culture. 2. Preincubation with the NMDA antagonists zinc (3-30 microM) and magnesium (30-300 microM) reduced subsequent responses to 100 microM NMDA applied together with these antagonists. No time dependence of antagonism was observed when responses were measured at the start and at the end of NMDA pulses 1.25-1.5 s in duration. 3. Two competitive antagonists of similar affinity in equilibrium experiments, D-2-amino-5-phosph
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&NA;. "Competitive NMDA antagonist shows anxiolytic potential." Inpharma Weekly &NA;, no. 1035 (1996): 7. http://dx.doi.org/10.2165/00128413-199610350-00015.

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Dissertations / Theses on the topic "Potential antagonist"

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Sullivan, Shannon M. "Synthesis of 2,4-disubstituted pyrimidine derivatives as potential 5-HT7 receptor antagonist." unrestricted, 2008. http://etd.gsu.edu/theses/available/etd-05052008-153400/.

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Thesis (M.S.)--Georgia State University, 2008.<br>Title from file title page. Lucjan Strekowski, committee chair; A.L. Baumstark, Gabor Patonay, Doyle Barrow , committee members. Electronic text (68 p. : ill.) : digital, PDF file. Description based on contents viewed June 23, 2008. Includes bibliographical references (p. 42-430.
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Picken, Paula. "The synthesis of endothelin analogues : potential application to immunoassay and receptor antagonist development." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318826.

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Jali, Abdulmajeed. "DISCOVERY OF MOR SELECTIVE, REVERSIBLE OPIOID ANTAGONIST FOR POTENTIAL USE IN TREATMENT OF DRUG DEPENDENCE." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/5020.

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Abstract DISCOVERY OF MOR SELECTIVE, REVERSIBLE OPIOID ANTAGONIST FOR POTENTIAL USE IN TREATMENT OF DRUG DEPENDENCE Abdulmajeed M. Jali, M.S. A thesis submitted in partial fulfillment of the requirements of Master of Science at Virginia Commonwealth University. Virginia Commonwealth University, 2017 Director: Dana E. Selley, Ph. D., Department of Pharmacology and Toxicology Opioid dependence/addiction is a major public health problem that is associated with multiple health and social costs. Pharmacotherapeutic treatment has been relatively effective, but the risk of relapse after treatment rem
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Natividad, Gaudencio M. "Isolation and chemical and pharmacological characterization of potential trace amine-associated receptor antagonist from plant sources." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/54392/.

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The present study describes the preliminary evaluation of Philippine medicinal plants <italic>Artemisia vulgaris, Chrysanthemum coronarium, Moringa oleifera, Sesbania grandiflora</italic> and <italic>Vitex negundo</italic> for their antagonistic activity at selected biogenic amine receptors on smooth muscle of the airways, gastrointestinal tract and vascular system. The antagonistic activity of these plants were studied against dose-response curves for contractions of the guinea pig ileum, trachea and aorta to 5-hydroxytryptamine (5-HT2 receptors), methacholine (M3 muscarinic receptors), hista
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Quintero, Emmeris Ivan Quintero. "Insumos e indicadores Biol?gicos em Agrossistemas com Bananeiras." Universidade Federal Rural do Rio de Janeiro, 2010. https://tede.ufrrj.br/jspui/handle/jspui/1165.

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Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-08-17T13:45:07Z No. of bitstreams: 1 2010 - Emmer?s Ivan Q. Quintero.pdf: 1261300 bytes, checksum: 0078bde3a7d0a80eea89948870dd7901 (MD5)<br>Made available in DSpace on 2016-08-17T13:45:07Z (GMT). No. of bitstreams: 1 2010 - Emmer?s Ivan Q. Quintero.pdf: 1261300 bytes, checksum: 0078bde3a7d0a80eea89948870dd7901 (MD5) Previous issue date: 2010-03-29<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES<br>Studies were performed in the experimental area of Embrapa Agrobiologia, region - RJ, in order to evaluate the asso
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Han, Rui [Verfasser]. "Identification of triptolide as a potential aryl hydrocarbon receptor antagonist in human T cells and keratinocytes / Rui Han." Kiel : Universitätsbibliothek Kiel, 2011. http://d-nb.info/1020245166/34.

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Smith, Andra Marie Carleton University Dissertation Psychology. "A profile of the pharmacotherapeutic potential of the dopamine autoreceptor antagonist ( - )-DS121 using the self-administration paradigm in the rat." Ottawa, 1993.

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Obeng, Samuel. "Design, Synthesis, and Biological Screening of Selective Mu Opioid Receptor Ligands as Potential Treatments for Opioid Addiction." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4771.

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Today, more Americans die each year because of drug overdoses than are killed in motor vehicle accidents. In fact, in 2015, more than 33,000 individuals died due to an overdose of heroin or prescription opioids. Sadly, 40-60 % of patients on current opioid addiction treatment medications relapse. Studies have shown that the addiction/abuse liability of opioids are abolished in mu opioid receptor (MOR) knock-out mice; this indicates that the addiction and abuse liability of opioids are mainly mediated through MOR. Utilizing the “message-address concept”, the our laboratory reported a novel non-
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Saber, Yasir Hazim. "Preclinical evaluation of a potential treatment for ADHD targeting the serotonin 1B receptor subtype." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1566553528266516.

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Fournet, Steven P. "High Resolution X-ray Diffraction Analysis of CB1 Receptor Antagonists as a Means to Explore Binding Affinity." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1737.

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Abstract Charge density studies have been conducted on ten CB1 cannabinoid receptor antagonists via high resolution x-ray crystallography. Bond critical point values and various other properties derived from these studies including the electrostatic potential were analyzed in correlation to the affinity of each compound with the CB1 receptor. Correlation/anti-correlation was found between several properties and Ki. The data was also interpreted by principal component analysis with three principal components accounting for 85% of the data variation. Data mining was limit due to the low sample c
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Books on the topic "Potential antagonist"

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Sirinathsinghji, Dalip J. S., and Ray G. Hill, eds. NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5.

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Rayat, Harnak Singh. The synthesis of potential steroid receptor antagonists. typescript, 1995.

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Henter, Ioline D., and Rodrigo Machado-Vieira. Novel therapeutic targets for bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0030.

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The long-term course of bipolar disorder (BD) comprises recurrent depressive episodes and persistent residual symptoms for which standard therapeutic options are scarce and often ineffective. Glutamate is the major excitatory neurotransmitter in the central nervous system, and glutamate and its cognate receptors have consistently been implicated in the pathophysiology of mood disorders and in the development of novel therapeutics for these disorders. Since the rapid and robust antidepressant effects of the N-methyl-D-aspartate (NMDA) antagonist ketamine were first observed in 2000, other NMDA
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Sirinathsinghji, Dalip J. S. NMDA Antagonists as Potential Analgesic Drugs. Springer, 2012.

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Scheipers, Sibylle. Clausewitz and the Eighteenth-Century Context of Partisan Warfare. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198799047.003.0002.

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Clausewitz was an ardent analyst of partisan warfare. In 1810 and 1811, he lectured at the Berlin Kriegsschule, the war academy, on the subject of small wars. Clausewitz’s lectures focused on the tactical nature of small wars. However, the eighteenth-century context was by no means irrelevant for Clausewitz’s further intellectual development. On the contrary, he extrapolated from his analysis of the tactical nature of small wars their strategic potential, as well as their exemplary nature for the study of war as such. The partisan, in Clausewitz’s eyes, possessed exemplary qualities in that he
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Dalip J.S. Sirinathsinghji (Editor) and Ray G. Hill (Editor), eds. NMDA antagonists as potential analgesic drugs (Progress in Inflammation Research). Birkhäuser Basel, 2002.

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Steiner, Michel Alexander. Insomnia and beyond - Exploring the therapeutic potential of orexin receptor antagonists. Edited by Christopher J. Winrow. Frontiers SA Media, 2014. http://dx.doi.org/10.3389/978-2-88919-330-1.

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Ling, Walter, and Matthew Torrington. Integrative Approach to Opiates, Opioids, and Opiate Use Disorder. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0008.

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This chapter defines terms such as “opiate” and “opioid” and explains their physiological functions as agonist, antagonist, and partial agonist. It notes the long history of medicinal opioid use for acute pain, as well as the curse of addiction with chronic use, highlighting the three opioid use epidemics in the United States: the morphine addiction of the Civil War era, the heroin addiction of the Vietnam War era, and the current epidemic of prescription opioid addiction. The chapter describes the commonly encountered natural, synthetic, and semi-synthetic opioids, noting their therapeutic us
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Shapiro, Benjamin. Ibogaine: History, Pharmacology, Spirituality, & Clinical Data. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0027.

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Ibogaine is an indole alkaloid derived from the African shrub Tabernathe iboga with broad anti-addictive, anti-depressant, and central nervous system stimulating effects. It is categorized as an oneriogen (or atypical hallucinogen) and has been used in West African tribal rituals for centuries. It was identified by French explorers in the early 1900s, came to the United States in the 1960s, and became marginalized in the mid-1990s after adverse outcomes halted federally funded human trials. Since then legal ibogaine treatment clinics have been established in countries without use restrictions.
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Webster, Wendy. The Empire Comes to Britain. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198735762.003.0004.

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This chapter looks at the many people who arrived in Britain from the British Empire—some to serve in the armed forces, others as war workers and wartime propagandists working at the BBC and in British cinema. Mixing between imperial allies produced many close friendships and camaraderie. The British media promoted a vision of an imperial community of allies. But wartime propaganda was potentially undermined by evidence of the practice of colour bars—in the empire and in Britain—and of tensions and antagonisms between imperial allies. Disruption of a publicly disseminated vision of a united em
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Book chapters on the topic "Potential antagonist"

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Bremner, William J., Carrie J. Bagatell, and Robert A. Steiner. "Gonadotropin Releasing Hormone Antagonist Plus Testosterone: A Potential Male Contraceptive." In Modes of Action of GnRH and GnRH Analogs. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4612-2916-2_21.

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Rothwell, Nancy J., and Sarah A. Loddick. "Interleukin-1 and IL-1 receptor antagonist in stroke: mechanisms and potential therapeutics." In Inflammation and Stroke. Birkhäuser Basel, 2001. http://dx.doi.org/10.1007/978-3-0348-8297-2_14.

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Sirinathsinghji, Dalip J. S., and Ray G. Hill. "Introduction." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_1.

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Sirinathsinghji, Dalip J. S., and Ray G. Hill. "Future prospects for improved analgesic therapy." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_10.

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Priestley, Tony. "Pharmacology and electrophysiology of excitatory amino acid receptors." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_2.

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Rigby, Michael, Robert P. Heavens, David Smith, Ruth O’Donnell, Ray G. Hill, and Dalip I. S. Sirinathsinghji. "Distribution of NMDA receptors in brain and spinal cord." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_3.

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Cumberbatch, Michael J., Boris A. Chizh, and P. Max Headley. "Spinal nociceptive processing: NMDA receptors and modulation by neuropeptides." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_4.

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Ma, Qing-Ping, and Clifford J. Woolf. "The NMDA receptor, pain and central sensitization." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_5.

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Le Guen, Stéphanie, Victoria Chapman, and Jean-Marie Besson. "Some pharmacological aspects of NMDA-mediated nociceptive transmission in the rat spinal cord as revealed by c-Fos immunocytochemistry." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_6.

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Dickenson, Anthony H., and Fiona C. Taylor. "Interaction of NMDA and other neurotransmitter receptor systems in modulation of nociception." In NMDA Antagonists as Potential Analgesic Drugs. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8139-5_7.

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Conference papers on the topic "Potential antagonist"

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Gómez-Carreño, Carlos Rodríguez, Antonio Ramírez García, Luis Beato Fernández, Irene Díaz Quero, and Estefanía Segura Escobar. "Craving and Priming of alcohol in depressive disorders. Bibliographic review and new therapies." In 22° Congreso de la Sociedad Española de Patología Dual (SEPD) 2020. SEPD, 2020. http://dx.doi.org/10.17579/sepd2020p140.

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Acute alcohol consumption produces positive reinforcement effects, through activation of brain reward circuit, includes limbic system structures (accumbens system and hippocampus). The comorbidity of depressive episode and alcohol abuse makes it necessary to propose new strategies for the treatment of this frequent clinical situation. We conducted a literature review of the combined treatments for major depressive disorder (MDD) with alcohol abuse. We review current literature on the use of new treatments in alcohol consumption with pattern of abuse (binge drinking). Recent studies support the
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Veras, Flávio Fonseca, Ana Paula Folmer Correa, Maievi Fonini, Tiago Centeno Einloft, Juliane Elisa Welke, and Adriano Brandelli. "Screening of Bacillus Spp. Isolated From Amazon Basin As Potential Antagonist of Toxigenic Fusarium Graminearum." In XII Latin American Congress on Food Microbiology and Hygiene. Editora Edgard Blücher, 2014. http://dx.doi.org/10.5151/foodsci-microal-044.

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Gill, M. W., S. Lakshmi, P. T. W. Cheng, et al. "BMS-986278, an LPA1 Receptor Antagonist for Idiopathic Pulmonary Fibrosis: Preclinical Assessments of Potential Hepatobiliary Toxicity." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5882.

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Guo, Yi, Elyssa Rubin, Jonathan Pourmorady, et al. "Abstract 236: DKK-3, a secreted Wnt antagonist, suppresses tumorigenic potential and lung metastasis of osteosarcoma." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-236.

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Dihia, Meghnem, Sebastien Morisseau, Kilian Trillet, et al. "Abstract B033: A novel IL-2 and IL-15 antagonist shifting the immune balance towards tolerance: Potential therapeutic applications." In Abstracts: Second CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 25-28, 2016; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6066.imm2016-b033.

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Arnout, J., A. Van Hecken, I. Delepeleire, et al. "EFFECTIVENESS AND TOLERABILITY OF CV-3988, A SELECTIVE PAF ANTAGONIST, AFTER INTRAVENOUS ADMINISTRATION TO MAN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642878.

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Platelet activating factor (PAF) is a naturally occurring phospholipid with a wide spectrum of biological activities. Although PAF has been ascribed a potential role in various conditions including inflammation, asthma, glomerulonephritis and thrombosis, its precise function in physiologic/pathophysiologic processes remains unclear. The introduction of selective PAF receptor antagonists could represent a useful tool to extend our knowledge of the role of this mediator in health and disease.We have investigated the efficacy and tolerability of (RS)-2-methoxy-3-(octadecylcarbomoyloxy)propy1 2-(3
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Lukiati, Betty, Sulisetijono, Frida Kunti Setiowati, and Anggi Klaritasari. "Potential prediction of phenolic compounds in red ginger (Zingiber officinale var. rubrum) as an AT1R antagonist by bioinformatics approach for antihypertensive oral drug candidates." In INTERNATIONAL CONFERENCE ON LIFE SCIENCES AND TECHNOLOGY (ICoLiST 2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0052726.

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Esposito, Mark, John L. Magnani, and Yibin Kang. "Abstract 4039: Exploration of a potent E-Selectin antagonist (GMI-1271) as a potential novel therapeutic for treating breast cancer metastasis to the bone and lung." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4039.

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Champaigne, Kevin D., Sarette N. Jenderny, and Jiro Nagatomi. "Electrophysiological Investigation of Hydrostatic Pressure Mechanotransduction by Urothelial Cell Lines." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53518.

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The urothelium is the epithelial lining of the ureters, urinary bladder, and urethra. Recent discoveries have suggested that in addition to providing a barrier function to urine, the urothelium actively participates in sensory functions related to thermal, chemical, and mechanical stimuli, and releases chemical signals in response[1]. In addition to a sensitivity to cell membrane stretch caused by wall tension upon bladder filling, in vitro studies by our group have shown that urothelial cells may be sensitive to hydrostatic pressure directly without requiring membrane stretching [2]. Specific
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Hoover, Carl D., and Kevin B. Fite. "Preliminary Evaluation of Myoelectric Control of an Active Transfemoral Prosthesis During Stair Ascent." In ASME 2010 Dynamic Systems and Control Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/dscc2010-4158.

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This paper presents the development and preliminary validation of a control interface for a transfemoral prosthesis that enables EMG-based control of a powered knee during stair ascent. The approach uses results from non-amputee gait studies of stair ascent in the design of a control architecture that enables EMG modulation of knee torque in a manner biomechanically similar to that exhibited by non-amputee subjects. The myoelectric torque controller is formulated with a finite-state linear impedance model in stance and swing. The stance phase is modulated by surface EMG signals co-activated by
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Reports on the topic "Potential antagonist"

1

Blaha, Michael D., and David A. DuBose. A Human Whole Blood Model for Screening Potential Vesicant Antagonists. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405432.

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2

Idakwo, Gabriel, Sundar Thangapandian, Joseph Luttrell, Zhaoxian Zhou, Chaoyang Zhang, and Ping Gong. Deep learning-based structure-activity relationship modeling for multi-category toxicity classification : a case study of 10K Tox21 chemicals with high-throughput cell-based androgen receptor bioassay data. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41302.

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Deep learning (DL) has attracted the attention of computational toxicologists as it offers a potentially greater power for in silico predictive toxicology than existing shallow learning algorithms. However, contradicting reports have been documented. To further explore the advantages of DL over shallow learning, we conducted this case study using two cell-based androgen receptor (AR) activity datasets with 10K chemicals generated from the Tox21 program. A nested double-loop cross-validation approach was adopted along with a stratified sampling strategy for partitioning chemicals of multiple AR
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