Relevant bibliographies by topics / Ptk2b

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Ptk2b'

Author: Grafiati
Published: 15 June 2024
Last updated: 31 July 2025

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Journal articles on the topic "Ptk2b"

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Pallarès, Victor, Montserrat Hoyos, M. Chillón, et al. "Focal Adhesion Genes Refine the Intermediate-Risk Cytogenetic Classification of Acute Myeloid Leukemia." Cancers 10, no. 11 (2018): 436. http://dx.doi.org/10.3390/cancers10110436.

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In recent years, several attempts have been made to identify novel prognostic markers in patients with intermediate-risk acute myeloid leukemia (IR-AML), to implement risk-adapted strategies. The non-receptor tyrosine kinases are proteins involved in regulation of cell growth, adhesion, migration and apoptosis. They associate with metastatic dissemination in solid tumors and poor prognosis. However, their role in haematological malignancies has been scarcely studied. We hypothesized that PTK2/FAK, PTK2B/PYK2, LYN or SRC could be new prognostic markers in IR-AML. We assessed PTK2, PTK2B, LYN an
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Porter, Tyrel, Miguel Mayol del Valle, and Lilia Kucheryavykh. "Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population." International Journal of Molecular Sciences 25, no. 9 (2024): 4947. http://dx.doi.org/10.3390/ijms25094947.

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Glioblastoma (GBM), an aggressive form of brain cancer, has a higher incidence in non-Hispanics when compared to the US Hispanic population. Using data from RT-PCR analysis of 21 GBM tissue from Hispanic patients in Puerto Rico, we identified significant correlations in the gene expression of focal adhesion kinase and proline-rich tyrosine kinase (PTK2 and PTK2B) with NGFR (nerve growth factor receptor), PDGFRB (platelet-derived growth factor receptor B), EGFR (epithelial growth factor receptor), and CXCR1 (C-X-C motif chemokine receptor 1). This study further explores these correlations found
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Chen, Cui, Zhen Tao, Ya Li, Jie Li, and Yang Xu. "MicroRNA214 expression inhibits HCC cell proliferation through PTK2b/ Pyk2." Cellular and Molecular Biology 68, no. 1 (2022): 20–25. http://dx.doi.org/10.14715/cmb/2022.68.1.4.

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MicroRNAs (miRNAs/miRs) are crucial regulatory molecules that act as the most significantly downregulated microRNAs in hepatocellular carcinoma (HCC). PTK2b/Pyk2 is a non-receptor protein tyrosine kinase, which plays an important role in the development and metastasis of cancer. In this study, we explored the expression level and functional relationship between MicroRNA-214 (miR-214) and PTK2b/ Pyk2 in liver cancer cells. For this purpose, we analyzed the expression of miR-214 and PTK2b/Pyk2 in 38 cases of HCC and paired non-neoplastic tissue specimens using real-time PCR. MTT, cell cycle and
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Luo, Jinping, Lynda K. McGinnis, Carol Carlton, Hilary E. Beggs, and William H. Kinsey. "PTK2b function during fertilization of the mouse oocyte." Biochemical and Biophysical Research Communications 450, no. 3 (2014): 1212–17. http://dx.doi.org/10.1016/j.bbrc.2014.03.083.

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Zeng, Ying, Lu-Qi Peng, Mei Zhang, Rong Zhong, Ke-Chao Nie, and Wei Huang. "Identification of potential biomarkers and pathways related to major depressive disorder by integrated bioinformatic analysis and experimental validation." Asian Pacific Journal of Tropical Biomedicine 15, no. 5 (2025): 200–209. https://doi.org/10.4103/apjtb.apjtb_750_24.

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Objective: To identify promising biomarkers for the pathogenesis of major depressive disorder (MDD). Methods: Microarray chips of MDD patients, including the GSE98793, GSE52790, and GSE39653 datasets, were obtained from the Gene Expression Omnibus database. The biological processes and pathways related to MDD were investigated using the GO and KEGG pathway tools. Weighted gene coexpression network analysis was conducted to identify modules related to MDD. The hub genes associated with MDD were obtained via protein-protein interaction analysis. Finally, the expression of hub genes in the hippoc
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N'Songo, Aurelie, Minerva M. Carrasquillo, Xue Wang, et al. "African American exome sequencing identifies potential risk variants at Alzheimer disease loci." Neurology Genetics 3, no. 2 (2017): e141. http://dx.doi.org/10.1212/nxg.0000000000000141.

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Objective:In African Americans, we sought to systematically identify coding Alzheimer disease (AD) risk variants at the previously reported AD genome-wide association study (GWAS) loci genes.Methods:We identified coding variants within genes at the 20 published AD GWAS loci by whole-exome sequencing of 238 African American participants, validated these in 300 additional participants, and tested their association with AD risk in the combined cohort of 538 and with memory endophenotypes in 319 participants.Results:Two ABCA7 missense variants (rs3764647 and rs3752239) demonstrated significant ass
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Giralt, Albert, Benoit de Pins, Carmen Cifuentes-Díaz, et al. "PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease." Experimental Neurology 307 (September 2018): 62–73. http://dx.doi.org/10.1016/j.expneurol.2018.05.020.

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Ni, Bin, Jared S. Farrar, Shanshan Chen, Joseph C. Lownik, and Francesco S. Celi. "A novel role for PTK2B in cultured beige adipocyte differentiation." Biochemical and Biophysical Research Communications 501, no. 4 (2018): 851–57. http://dx.doi.org/10.1016/j.bbrc.2018.05.021.

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Liu, Yu, Dongfa Lin, Syeda Sadia Najam, et al. "Functional redundancy between glucocorticoid and mineralocorticoid receptors in mature corticotropin‐releasing hormone neurons protects from obesity." Obesity 32, no. 10 (2024): 1885–96. http://dx.doi.org/10.1002/oby.24116.

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AbstractObjectiveHere, we aimed to investigate the role of glucocorticoid and mineralocorticoid receptors (GRs and MRs, respectively) in the regulation of energy homeostasis.MethodsWe used three mouse models with simultaneous deletion of GRs and MRs in either forebrain neurons, the paraventricular nucleus, or corticotropin‐releasing hormone (CRH) neurons and compared them with wild‐type controls or isolated knockout groups. In addition to body weight, food intake, energy expenditure, insulin sensitivity, fat/lean mass distribution, and plasma corticosterone levels, we also performed transcript
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Chu, Weiwei, Lili Guan, Dihua Huang, Yuezhong Ren, and Yan Zhou. "Lovastatin exerts protective effects on endothelial cells via upregulation of PTK2B." Experimental and Therapeutic Medicine 12, no. 3 (2016): 1741–49. http://dx.doi.org/10.3892/etm.2016.3547.

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Dissertations / Theses on the topic "Ptk2b"

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Melo, de Farias Ana Raquel. "Probing the Alzheimer’s disease risk gene PTK2B using human-derived induced neurons." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILS062.

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La maladie d'Alzheimer (MA) est le principal type de démence et représente un défi majeur pour la santé publique mondiale. Elle se caractérise par un déclin progressif de la cognition, de la mémoire et des fonctions comportementales et touche plus de 55 millions de personnes dans le monde. Au niveau moléculaire, la MA se définit par la présence d'enchevêtrements neurofibrillaires agrégés dans les neurones et par l'accumulation de plaques d'amyloïde-β (Aβ) dans le cerveau. Ces caractéristiques pathologiques sont associées à des altérations de l'activité neuronale, à la perte de synapses, à la g
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Schmachtenberg, Anna-Juliane. "Differentielle Expression des Tyrosin-Kinoms bei akuter lymphatischer Leukämie des erwachsenen Alters." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/19369.

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Tyrosinkinasen (TK) sind Schlüsselregulatoren der zellulären Signaltransduktion und beeinflussen Zellzyklus, Zellüberleben, Apoptose, Proliferation und Differenzierung. Die Dysregulation der TK-Aktivität trägt zur Entwicklung von Leukämie und anderen malignen Erkrankungen bei. So sind 25% der akuten lymphatischen Leukämien bei Erwachsenen (ALL) durch die BCR-ABL1-Translokation bedingt. Trotz intensiver Therapie beträgt das 5-Jahres-Überleben von erwachsenen Patienten mit ALL nur etwa 50 %. Als Alternative zu herkömmlichen Chemotherapeutika bietet der Einsatz von spezifisch wirkenden TK-Inhibit
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LI, PETRI Giovanna. "SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW IMIDAZO[2,1-b][1,3,4]THIADIAZOLE DERIVATIVES AS ANTICANCER AND ANTIBIOFILM AGENTS, AND PRECLINICAL INVESTIGATION OF ANTI-LDH-A COMPOUNDS AGAINST MALIGNANT MESOTHELIOMA." Doctoral thesis, Università degli Studi di Palermo, 2020. http://hdl.handle.net/10447/395253.

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Book chapters on the topic "Ptk2b"

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Beck, T., A. Danneberg, and V. Friedberg. "Wertigkeit histomorphologischer Befunde für die Ergebnisse operativer Therapie des Zervixkarzinom im Stadium pT2b." In Gynäkologie und Geburtshilfe 1988. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74784-7_282.

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Vernetti, Lawrence A., A. Jay Gandolfi, and Raymond B. Nagle. "Selective Alteration of Cytokeratin Intermediate Filament by Cyclosporine A is a Lethal Toxicity in PTK2 Cell Cultures." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_119.

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"PTK2." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_103157.

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Safer, Daniel, and Vivianne T. Nachmias. "Thymosin β4." In Guidebook to the Cytoskeletal and Motor Proteins. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780198599579.003.0049.

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Abstract There is good agreement that increasing T,β4 by microinjection or by transient transfection leads to disassembly of stress fibre bundles in NRK, PtK2, and CV1 cells (see Fig. 1 for a living PtK2 cell), and micro-injection at high concentrations also leads to disappearance of submembranous F-actin and relaxation of the cytokinetic furrow,15 This is what would be expected if the added β4 thymosin were acting in vivo to further sequester G-actin.
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Frederick, K. "Irrigation efficiency, a key issue." In Water Crisis. Taylor & Francis, 2006. http://dx.doi.org/10.1201/9781439834275.pt2b.

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"Conclusion to Part II." In XML Databases and the Semantic Web. CRC Press, 2002. http://dx.doi.org/10.1201/9781420000023.pt2b.

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"Some problems in the use of language in economics." In Economics of Legal Relationships. Routledge, 2007. http://dx.doi.org/10.4324/9780203964675.pt2b.

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Carvalho, D., J. Paschoalin Filho, and P. Albuquerque. "Behavior of continuous flight auger piles subjected to uplift load tests in unsaturated diabasic soil." In Deep Foundations on Bored and Auger Piles - BAP V. CRC Press, 2008. http://dx.doi.org/10.1201/9780203882870.pt2b.

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Roovers, G., I. Rocabado, and M. Huygens. "Future flood risks and comprehensive flood management." In Water and Urban Development Paradigms. CRC Press, 2008. http://dx.doi.org/10.1201/9780203884102.pt2b.

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"Conclusion to Part II." In Managing and Mining Multimedia Databases. CRC Press, 2001. http://dx.doi.org/10.1201/9781420042559.pt2b.

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Conference papers on the topic "Ptk2b"

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Ono, Matthew D., Daryl Preece, Michelle L. Duquette, and Michael W. Berns. "Mitotic Tethers Connect Sister Chromosomes During Anaphase A in PtK2 Cells." In Optical Trapping Applications. OSA, 2017. http://dx.doi.org/10.1364/ota.2017.otm4e.4.

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Skinner, Heath D., Uma Giri, John S. Yordy, et al. "Abstract 3441: Proteomic profiling identifies PTK2/FAK as a targetable marker of radioresistance in head and neck cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3441.

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Gomard, Guillaume, Donie Yidenekachew, Radwanul Hasan Siddique, et al. "Controlling disorder for improved light management in solar cells." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.pth2b.1.

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Isabella, O., R. Vismara, A. Ingenito, and M. Zeman. "Decoupled front/back dielectric textures for flat ultrathin c-Si solar cells." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.pth2b.2.

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Abass, Aimi, and Carsten Rockstuhl. "Analytical Model of Guided Modes in Structures with Rough Surfaces." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.pth2b.3.

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Ding, H., L. Lalouat, B. Gonzalez-Acevedo, et al. "Pseudo-disordered design assists mono-crystalline Si thin film solar cells." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.pth2b.4.

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Schumann, M. F., A. Abass, S. Wiesendanger, C. Rockstuhl, and M. Wegener. "Cloaking of Contact Fingers on Solar Cells Enabled by Transformation Optics." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.ptu2b.3.

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Li, Juntao, Kezheng Li, Christian Schuster, et al. "Fourier analysis and Spatial resolution of light trapping nanostructures." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.pth2b.5.

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Krč, Janez, and Marko Topič. "Nanostructures for light trapping in photovoltaic devices – approaches and challenges." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.ptu2b.1.

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Mellor, A., N. P. Hylton, F. Shirley, et al. "Nanostructured Solar Cells: Surface Textures and Quantum Dots." In Optical Nanostructures and Advanced Materials for Photovoltaics. OSA, 2015. http://dx.doi.org/10.1364/pv.2015.ptu2b.2.

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