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Dissertations / Theses on the topic 'Pulmonary disease chronic obstructive/complications'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Lo, Iek-long, and 羅奕龍. "Impacts of cognitive impairment on acute exacerbations of chronic obstructive pulmonary disease among Chinese elderly patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45830770.

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2

Cabral, Marília Montenegro. "Apnéia obstrutiva do sono em pacientes portadores da doença pulmonar obstrutiva crônica: impacto do padrão clínico-funcional." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-10102014-120458/.

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A Apnéia Obstrutiva do Sono (AOS) e a Doença Pulmonar Obstrutiva Crônica (DPOC) são condições clínicas comuns, particularmente na população de idosos, e portanto é de se esperar que um grande número de pacientes com DPOC apresente AOS. Os pacientes portadores da DPOC podem ser divididos em dois tipos clínicos, A e B. O segundo apresenta características clínicas sugestivas da AOS. A prevalência da AOS entre os portadores da DPOC permanece controversa e existem poucos estudos sistemáticos correlacionando a presença da AOS com o tipo clínico da DPOC. Os objetivos primários do nosso estudo foram:

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3

McAllister, David Anthony. "Chronic obstructive pulmonary disease, pulmonary function and cardiovascular disease." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5615.

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Cardiovascular disease is common in Chronic Obstructive Pulmonary Disease (COPD), and forced expiratory volume in one second (FEV1) independently predicts cardiovascular morbidity and mortality. Pathological changes in the systemic vasculature have been proposed as potential mechanisms linking COPD to cardiovascular disease, and patients with COPD may be at increased risk of acute myocardial infarction during acute exacerbations. Notwithstanding causation, FEV1 may be a useful prognostic marker in patients undergoing cardiac surgery. This thesis examined these three aspects of cardiovascular c

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4

Murphy, Nicola. "Chronic obstructive pulmonary disease and anxiety." Thesis, Coventry University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368862.

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5

Roos-Engstrand, Ester. "T cells in chronic obstructive pulmonary disease." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33677.

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6

Al-shair, Khaled. "Systemic Manifestations of Chronic Obstructive Pulmonary Disease." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509061.

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7

Revill, Susan M. "Endurance exercise in chronic obstructive pulmonary disease." Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/15388.

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8

Polkey, Michael Iain. "Diaphragm function in chronic obstructive pulmonary disease." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286262.

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9

Taylor, Abigail Elizabeth. "Macrophage phagocytosis in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/7374.

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The hypothesis examined in this thesis stated that macrophages from COPD subjects are defective in their ability to phagocytose. To investigate this hypothesis, engulfment by COPD macrophages was compared to that of cells from controls (smokers without COPD and non-smokers). Phagocytosis of polystyrene beads by monocytes-derived-macrophages (MDM) was comparable to that of alveolar macrophages, thus validating the MDM model. There was no difference in uptake of beads by any subject group, however, COPD MDM phagocytosed significantly less E. coli, H. influenzae and S. pneumoniae than cells from

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10

Baldrick, Francina Rose. "Diet and chronic obstructive pulmonary disease (COPD)." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527657.

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11

Stevenson, Nicola Jane. "Lung mechanics in chronic obstructive pulmonary disease." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432977.

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12

Donaldson, Anna. "Circulating microRNA in Chronic Obstructive Pulmonary Disease." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/24776.

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Skeletal muscle dysfunction in COPD is associated with increased morbidity. Novel agents might reverse skeletal muscle dysfunction through different mechanisms since the biopsy picture in COPD patients is heterogenous. Thus there is a need for a biomarker of skeletal muscle dysfunction which could both be measured in blood and obviate the need for a biopsy. Previous work has found that muscle-specific microRNA (miR-1, miR-499, miR-206 and miR-133) are down-regulated in the quadriceps of COPD patients. Tissue specific miRNA circulate in the blood at detectable levels and are currently under inv

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13

Greening, Neil James. "Early pulmonary rehabilitation for exacerbations of chronic obstructive pulmonary disease." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/29155.

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Exacerbations are key events in the natural history of chronic obstructive pulmonary disease (COPD), with limited recovery of physical performance, and the highest cause of readmission in the UK. This thesis explores the impact of exacerbations in COPD and chronic respiratory disease. In the first study I have investigated the effects of an early rehabilitation intervention on healthcare utilisation, strength and exercise capacity by conducting a large randomised control trial. Using a sub-group of this cohort I have then explored factors that predict hospital readmission. Finally I have condu

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14

John, Michelle. "The extra-pulmonary effects of chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14405/.

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Rationale Cardiovascular disease (CVD) is a leading cause of mortality in patients with COPD. Aortic stiffness, measured using aortic pulse wave velocity (PWV), an independent, non-invasive, predictor of CV risk; and inflammatory markers are increased in COPD. Screening tools for community based identification of increased CVD risk, and a proactive approach to addressing primary prevention of CVD is needed. Statins modulate aortic stiffness and are anti-inflammatory, but are not currently used for primary prevention in COPD. Objectives Proof of principle double-blind Randomised Control Trial (

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15

Solomon, Brahm Kevin. "Psychological Aspects of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34292.

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As a leading cause of disability that often leads to death, chronic obstructive pulmonary disease (COPD) can be characterized as both a chronic illness and a life-threatening one. As a result, the experience of individuals with COPD can include psychological concerns that are associated with both rehabilitation and palliative care. At the same time, the often-uncertain trajectory of COPD obscures a clear transition from rehabilitation to palliative care. It is not surprising, therefore, that treatments aimed at addressing patients’ rehabilitative and palliative needs largely proceed independen

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16

Sze, Marc Alexander. "The lung microbiome in chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36343.

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Until recently the normal human lung was thought to be sterile below the larynx, but recent reports from other laboratories indicate that a diverse microbiome exists and becomes less diverse in smokers. These reports led naturally to the hypothesis that pathogens emerging from the abnormal microbiome in smokers could drive the innate and adaptive immune response that has been associated with the pathology of peripheral lung abnormalities observed in Chronic Obstructive Pulmonary Disease (COPD). The purpose of the present study was to examine this hypothesis in human lung tissue. This began wit

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17

Camp, Patricia. "Sex and gender in chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1410.

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Research on sex and gender in chronic obstructive pulmonary disease (COPD) has primarily focused on differences in pulmonary function. Detailed gender- and sex-based analyses of other aspects of COPD, including epidemiology, risk factors other than cigarette smoke, pathophysiology, and measurement tools are warranted. In Chapter Two we analyzed administrative health services data to compare the prevalence, mortality and use of drugs and spirometry in men and women with COPD. Contrary to recent predictions, we did not detect a dramatic increase in the prevalence or mortality of COPD over tim

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18

Puhan, Milo Alan. "Patient-oriented research in chronic obstructive pulmonary disease /." Zürich, 2005. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000253399.

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19

Hopkinson, Nicholas Shaun. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417140.

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20

Urbanowicz, Richard Antoni. "Peripheral cytotoxic cells in chronic obstructive pulmonary disease." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490982.

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Chronic obstructive pulmonary disease (COPD) is a treatable and preventable disease state, characterised by progressive airflow limitation that is not fully reversible. Although primarily a disease that affects the airways, COPD is increasingly recognised as a systemic disease. It is a current and growing cause of mortality and morbidity worldwide, with the World Health Organization (WHO) projecting that total deaths attributed to COPD will increase by more than 30% in the next 10 years, making it the third major cause of death worldwide.

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21

Swallow, Elisabeth. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508993.

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22

Eltboli, Osama M. I. "Eosinophilic airways inflammation in Chronic Obstructive Pulmonary Disease." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32546.

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Background: Eosinophilic airway inflammation (>3% sputum eosinophils) is a feature of subgroup of subjects with chronic obstructive pulmonary disease (COPD). My objectives were to investigate the clinical characteristics of eosinophilic COPD, its stability over time and extent in bronchial tissue, whether it is related to parasite exposure or atopy and whether its persistence is due to abnormal clearance by macrophages. Methods: Subjects were studied that had participated in previous observational studies. The repeatability of sputum eosinophils was measured between 3 monthly visits for 1 year

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23

Hobbs, Brian. "Exome Array Analysis of Chronic Obstructive Pulmonary Disease." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:22837731.

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Background: Chronic obstructive pulmonary disease (COPD) susceptibility is in part related to genetic variants. Most genetic studies have focused on common variation, but rare coding variants are known to affect COPD susceptibility. We hypothesized that an exome array analysis would identify single non-synonymous variants and gene-based aggregates of non-synonymous variants associated with COPD. Methods: We used the Illumina HumanExome array to genotype individuals in six COPD cohorts: Caucasian subjects from the family-based Boston Early-Onset COPD Study (BEOCOPD) and International COPD G

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24

Alhaddad, Maath. "Cardiopulmonary manifestations in chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30008/.

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Rationale Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with extrapulmonary manifestations- cardiovascular diseases (CVD), impaired physical function, activity and increased frailty. Integrating measures of function into community assessments is hindered by the space and time required. The association of function, activity and CVD has not been extensively investigated in COPD. Objectives Explore the potential utility of Time Up and Go (TUG) as a measure of physical function in COPD Assess association of non-invasive measures of haemodynamics to physical function

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25

Roberts, Della Kim. "The family experience with chronic obstructive pulmonary disease." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24422.

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This study was designed to gain an understanding of the family experience when an adult member has chronic obstructive pulmonary disease (COPD). It is recognized that illness within the family affects the well-being of the family unit and the health of all members. To understand the impact of COPD upon the family, however, the literature provides only knowledge of the experience of the individual who has COPD and the spouse, not that of the family unit. Thus, the purpose of this study was to describe and explain the COPD experience from the perspective of the family unit. A qualitative method

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26

Thomas, Catherine. "Defective innate immunity in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/40171.

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Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease, comprising chronic bronchitis, small airways fibrosis and emphysema. The primary risk factor for developing COPD, in industrialised nations is cigarette smoking. Exacerbations of COPD, of which approximately half are due to bacterial infection, are associated with worsening quality of life, more rapid decline in FEV1 and increased mortality. In healthy individuals, alveolar macrophages (AM) clear inhaled bacterial pathogens from the lung by phagocytosis, resulting in sterility of the lower respiratory tract. However

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27

Santiago, Pia Bantegui. "Adherence to exercise following pulmonary rehabilitation of chronic obstructive pulmonary disease /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3130214.

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28

Shaikh, Zarrin F. "Patent foramen ovale in obstructive sleep apnoea and chronic obstructive pulmonary disease." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9478.

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The objective of this thesis was to determine the impact of right to left shunting (RLS) through patent foramen ovale (PFO) on oxygen saturation in obstructive sleep apnoea (OSA) and chronic obstructive pulmonary disease (COPD). The first aim was to determine the prevalence of PFO in severe OSA and whether PFO closure improves nocturnal oxygen saturation. The data showed that PFO with large shunts were more prevalent, however overall prevalence was not statistically different when compared to healthy controls. PFO closure did not reduce nocturnal desaturation. The second aim was to determine w

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29

Schleifer, Taylor Jacqueline. "Exploring the social construction of chronic obstructive pulmonary disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ54197.pdf.

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30

Toma, Tudor Paul. "Endoscopic lung volume reduction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428589.

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31

Saha, Shironjit K. "Inflammatory profiles in chronic obstructive pulmonary disease and asthma." Thesis, University of Leicester, 2010. http://hdl.handle.net/2381/8206.

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Historically, asthma and chronic obstructive pulmonary disease (COPD) represent polar ends of the spectrum of airways disease defined in part by distinctive profiles of airway inflammation; in practice, overlap can exist between asthma and COPD. This thesis examined the pattern of inflammatory cell infiltration and cytokine expression within the bronchus in COPD and asthma with further study of moderate-severe asthma. In addition using sputum, cytokine expression was further assessed in COPD and asthma and its relation to severity. Based on previous studies, this thesis examined the expression

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32

Moore, Alastair. "Physiological approaches to hyperinflation in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505304.

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Chronic Obstructive Pulmonary Disease (COPD) is one of the leading causes of mortality and morbidity worldwide. The purpose of this thesis was to explore the role of hyperinflation in COPD by investigating its effect on mortality, and then having established that hyperinflation is a predictor of mortality in COPD, to then explore how it has an effect on the mechanics of the diaphragm at a sub-cellular level.

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33

Wainwright, Megan Julie. "Breathing and breathlessness : chronic obstructive pulmonary disease in Uruguay." Thesis, Durham University, 2013. http://etheses.dur.ac.uk/7270/.

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An increasingly common part of being human is living with chronic health problems for which management over time, and not cure, is the goal of medical treatment. One such chronic condition is chronic obstructive pulmonary disease (COPD), a lung disease caused by breathing-in smoke, dusts and chemicals, including tobacco smoke. This ethnographic study set out to explore how COPD is lived with and cared for in Uruguay, where rates of COPD are amongst the highest in South America and where most cases go undiagnosed. The aims of the research were to explore the following questions: a) what does it

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34

Rickards, Karen Jane. "Neutrophil phosphodiesterase inhibition in equine chronic obstructive pulmonary disease." Thesis, Royal Veterinary College (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251618.

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35

Correll, Amanda Leigh. "Strength training in patients with chronic obstructive pulmonary disease." Winston-Salem, NC : Wake Forest University, 2009. http://dspace.zsr.wfu.edu/jspui/handle/10339/42574.

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Thesis (M.S.)--Wake Forest University. Dept. of Health and Exercise Science, 2009.<br>Title from electronic thesis title page. Thesis advisor: Michael J. Berry. Includes bibliographical references (p. 49-54).

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36

Stockley, James. "Neutrophil migration and inflammation in chronic obstructive pulmonary disease." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5999/.

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COPD is a leading cause of morbidity and mortality worldwide and it is believed that the neutrophil is key to the pathology. Evidence to date suggests that neutrophils migrate less accurately in patients with COPD, although the precise mechanisms by which this occurs have not been defined. We have shown that COPD neutrophils migrate faster (chemokinesis) but less accurately (chemotaxis) in various chemokine gradients. It appears to be an intrinsic cell defect, as incubation of healthy neutrophils in COPD plasma did not alter migratory dynamics. This phenomenon does not occur in other respirato

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37

Heneghan, Nicola R. "Chronic obstructive pulmonary disease and cervico-thoracic musculoskeletal dysfunction." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4779/.

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Conservative non-pharmacological evidence-based management options for Chronic Obstructive Pulmonary Disease (COPD) primarily focus on developing physiological capacity. With co-morbidities, including those of the musculoskeletal system, contributing to the overall disease severity, further research was needed. This thesis presents a critical review of musculoskeletal management approaches used in COPD, which concluded there is insufficient evidence for using musculoskeletal interventions in COPD management. With a paucity of literature exploring chest wall flexibility and clinical guidelines

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38

Walton, Georgia May. "Neutrophil migration and phagocytosis in chronic obstructive pulmonary disease." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8647/.

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COPD is a leading cause of morbidity and mortality. A wealth of data supports a role of the neutrophil in disease pathogenesis. Despite abundance of neutrophils in airway secretions, patients suffer recurrent respiratory infections and colonisation suggesting immune dysfunction. This thesis describes impaired migratory function of neutrophils from patients with COPD, but not Alpha-1 Anti-Trypsin Deficiency (AATD) where similar inflammation is present. This is a feature of all COPD disease phenotypes and may constitute an early disease alteration to cell function, or a factor that predisposes p

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39

Jones, Sharon Scardina. "Evaluating a Discharge Bundle for Chronic Obstructive Pulmonary Disease." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4861.

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Acute exacerbation of chronic obstructive pulmonary disease (COPD) is one of the leading causes of hospital readmissions within 30 days. Frequent readmissions negatively affect hospital reimbursements and patient outcomes. Creative strategies, such as COPD care bundles, have been shown to reduce readmission rates according to existing studies. A COPD discharge bundle was developed and implemented at 1 community hospital in response to an identified problem with COPD readmissions. Evaluation of this quality improvement initiative was the purpose of this project study. The practice-focused quest

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40

Akiki, Zeina. "Biological Markers For Chronic Obstructive Pulmonary Disease And Asthma." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS081/document.

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L’étude des marqueurs biologiques dans la broncho-pneumopathie chronique obstructive (BPCO) et l'asthme, deux maladies respiratoires chroniques affectant des millions de personnes dans le monde, pourrait améliorer leur diagnostic, leur traitement et leur prévention.Cette thèse comprend deux parties. La première visait à évaluer l'association entre un marqueur spécifique des poumons, la protéine surfactant D (SP-D) sérique, et la BPCO, et à trouver un seuil de SP-D capable de discriminer les patients BPCO des témoins. Elle a été réalisée dans le cadre d’une étude cas-témoin au Liban incluant de

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41

Haldar, Kairabi Sadhu. "Profiling of bacterial communities in chronic obstructive pulmonary disease." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32292.

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Introduction: It is hypothesized that bacteria are important in the pathogenesis of COPD and exacerbations. Most bacteriological research in COPD has utilised culture based methods. Novel molecular approaches enable detailed evaluation of the airway microbiome that may better inform the role of bacteria in COPD. This project aimed to characterise the microbial community in COPD at stable state and during acute exacerbations through assessment of serial sputa at stable (S), exacerbation (E), follow up (F) and recovery (R) visits. Methods: Sputum from 145 clinical trial COPD patients was collect

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42

Chen, Roy Yu-Wei. "Biomarkers for acute exacerbation of chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57759.

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Rationale: There are currently no generally accepted and validated blood tests available for diagnosing acute exacerbations of chronic obstructive pulmonary disease (AECOPD). There is an urgent need of biomarkers that can guide therapeutic management in AECOPD. Based on literature review, systemic inflammation and mild cardiac dysfunction are often associated with AECOPD. We hypothesized that certain protein markers can indeed be useful in tracking and diagnosing AECOPD progression. Methods: The study cohort consisted of 368 patients recruited in the chronic obstructive pulmonary disease (COP

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43

McPherson, E. A. "Equine chronic obstructive pulmonary disease (COPD) : publications 1974-1985." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/28607.

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44

Bestall, Janine Caroline. "Outcome of pulmonary rehabilitation in patients with severe chronic obstructive pulmonary disease." Thesis, Queen Mary, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322237.

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45

Brazil, Timothy John. "Pulmonary neutrophil recruitment, activation and clearance in equine chronic obstructive pulmonary disease." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/29982.

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The functional status of neutrophils within both the circulating granulocyte pool and the airways of horses with COPD remains largely unexplored. Likewise, little is known of the kinetics of pulmonary neutrophil recruitment and clearance during and after an acute episode of COPD or indeed the subsequent fate of these cells. I have demonstrated <i>in vitro</i> that isolated peripheral blood neutrophils may be primed by exposure to inflammatory mediators such as lipopolysaccharide, platelet activating factor and tumour necrosis factor-a. This results in enhanced respiratory burst activity upon s

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46

Matsumoto, Takeshi. "Microalbuminuria in Patients with Obstructive Sleep Apnea-Chronic Obstructive Pulmonary Disease Overlap Syndrome." Kyoto University, 2018. http://hdl.handle.net/2433/232105.

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47

Sherman, Megan F. B. "The muscle metaboreflex during exercise in chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/20467.

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Chronic obstructive pulmonary disease (COPD) is characterised by deteriorating lung and airway function. Altered peripheral skeletal muscle properties, favouring glycolytic metabolism, are also well-documented in this population. Skeletal muscle properties such as those found in COPD patients may have significant effects on the magnitude of the muscle metaboreflex. Hypotheses: It was hypothesized that the muscle metaboreflex would be magnified in people with COPD compared to healthy controls, and that disease severity and exercise capacity would be correlated with the magnitude of the muscle m

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48

Batlle, Garcia Jordi de. "Measure and effect of diet in chronic obstructive pulmonary disease." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/52896.

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Background and objectives: Recent research has shown an association between a healthy diet and reduced chronic obstructive pulmonary disease (COPD) incidence. However, the potential role of diet in COPD prognosis is unknown. This thesis aimed to describe the characteristics of diet in COPD patients and to estimate its association with the disease evolution, in terms of pathophysiological impairment and hospitalizations. A secondary objective was to study the role of diet in asthma, as a COPDrelated phenotype. Methods: A dietary ancillary protocol was included in a well phenotyped cohort of 342

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49

Batlle, Garcia Jordi de 1981. "Measure and effect of diet in chronic obstructive pulmonary disease." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/52896.

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Background and objectives: Recent research has shown an association between a healthy diet and reduced chronic obstructive pulmonary disease (COPD) incidence. However, the potential role of diet in COPD prognosis is unknown. This thesis aimed to describe the characteristics of diet in COPD patients and to estimate its association with the disease evolution, in terms of pathophysiological impairment and hospitalizations. A secondary objective was to study the role of diet in asthma, as a COPDrelated phenotype. Methods: A dietary ancillary protocol was included in a well phenotyped coh

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50

Lytras, Theodoros 1987. "The Role of occupational exposures in Chronic Obstructive Pulmonary Disease." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/586017.

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Introduction: Occupational exposures are considered to be one of the newer and important risk factors for Chronic Obstructive Pulmonary Disease (COPD) besides tobacco smoking. However, the evidence mostly comes from smaller and cross-sectional studies and important questions remain unanswered, such as which specific exposures are responsible, the magnitude of the risk involved, and how the risk varies between men and women and between smokers and nonsmokers. The aim of this thesis was to examine the association between objectively assessed occupational exposures and changes in COPD-related out

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