Relevant bibliographies by topics / Purine and thiamine metabolism

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Purine and thiamine metabolism'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Purine and thiamine metabolism"

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Björk, Glenn R., and Kristina Nilsson. "1-Methylguanosine-Deficient tRNA of Salmonella enterica Serovar Typhimurium Affects Thiamine Metabolism." Journal of Bacteriology 185, no. 3 (2003): 750–59. http://dx.doi.org/10.1128/jb.185.3.750-759.2003.

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ABSTRACT In Salmonella enterica serovar Typhimurium a mutation in the purF gene encoding the first enzyme in the purine pathway blocks, besides the synthesis of purine, the synthesis of thiamine when glucose is used as the carbon source. On carbon sources other than glucose, a purF mutant does not require thiamine, since the alternative pyrimidine biosynthetic (APB) pathway is activated. This pathway feeds into the purine pathway just after the PurF biosynthetic step and upstream of the intermediate 4-aminoimidazolribotide, which is the common intermediate in purine and thiamine synthesis. The
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Christian, Todd, and Diana M. Downs. "Defects in pyruvate kinase cause a conditional increase of thiamine synthesis inSalmonella typhimurium." Canadian Journal of Microbiology 45, no. 7 (1999): 565–72. http://dx.doi.org/10.1139/w99-042.

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As genomic sequence data become more prevalent, the challenges in microbial physiology shift from identifying biochemical pathways to understanding the interactions that occur between them to create a robust but responsive metabolism. One of the most powerful methods to identify such interactions is in vivo phenotypic analysis. We have utilized thiamine synthesis as a model to detect subtle metabolic interactions due to the sensitivity allowed by the small cellular requirement for this vitamin. Although purine biosynthesis produces an intermediate in thiamine synthesis, mutants blocked in the
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Johnson, Samanthia R., Kelsey L. Bentley, Scott Bowdridge, and Ibukun M. Ogunade. "213 Lipopolysaccharide-induced alterations in the liver metabolome of St. Croix and Suffolk sheep." Journal of Animal Science 102, Supplement_3 (2024): 407. http://dx.doi.org/10.1093/jas/skae234.464.

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Abstract The development of resistance in parasites due to overuse of anthelmintics has resulted in a marked decrease in the efficacy of these drug classes. Recent research efforts have focused on exploring alternatives such as selection for parasite-resistant breeds with the implication that immunocompetence may align with parasite resistance. Two breeds that are often investigated are the St. Croix (STC), a resistant hair breed, and Suffolk (SUF), a susceptible wool breed sheep. The liver has a vital role in metabolism in the body and metabolizes lipopolysaccharide (LPS), which triggers whol
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Sahu, Umakant, Elodie Villa, Colleen R. Reczek, et al. "Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis." Science 383, no. 6690 (2024): 1484–92. http://dx.doi.org/10.1126/science.adh2771.

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Cellular purines, particularly adenosine 5′-triphosphate (ATP), fuel many metabolic reactions, but less is known about the direct effects of pyrimidines on cellular metabolism. We found that pyrimidines, but not purines, maintain pyruvate oxidation and the tricarboxylic citric acid (TCA) cycle by regulating pyruvate dehydrogenase (PDH) activity. PDH activity requires sufficient substrates and cofactors, including thiamine pyrophosphate (TPP). Depletion of cellular pyrimidines decreased TPP synthesis, a reaction carried out by TPP kinase 1 (TPK1), which reportedly uses ATP to phosphorylate thia
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Decsi, Kincső, Mostafa Ahmed, Donia Abdul-Hamid, Roquia Rizk, and Zoltán Tóth. "Verification of Seed-Priming-Induced Stress Memory by Genome-Wide Transcriptomic Analysis in Wheat (Triticum aestivum L.)." Agronomy 15, no. 6 (2025): 1365. https://doi.org/10.3390/agronomy15061365.

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In line with the latest challenges, agriculture has many options to protect against stress conditions. Seed-priming treatment was applied to winter wheat genotype AG Hurrem with Dr. Green seed-priming fertilizer, which is a commonly used seed fertilizer containing macro- and microelements. Genome-wide transcriptomic analysis was performed to examine the effects of treatments. In seed-primed plants, defense response pathways such as purine and thiamine metabolism, glutathione pathway, and phenylpropanoid biosynthesis were activated. At the same time, photosynthesis and some cellular respiration
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Miles, Lindsay S., Nadia A. Ayoub, Jessica E. Garb, Robert A. Haney, and Brian C. Verrelli. "Ovarian Transcriptomic Analyses in the Urban Human Health Pest, the Western Black Widow Spider." Genes 11, no. 1 (2020): 87. http://dx.doi.org/10.3390/genes11010087.

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Due to their abundance and ability to invade diverse environments, many arthropods have become pests of economic and health concern, especially in urban areas. Transcriptomic analyses of arthropod ovaries have provided insight into life history variation and fecundity, yet there are few studies in spiders despite their diversity within arthropods. Here, we generated a de novo ovarian transcriptome from 10 individuals of the western black widow spider (Latrodectus hesperus), a human health pest of high abundance in urban areas, to conduct comparative ovarian transcriptomic analyses. Biological
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Li, Zijian, Hao Wu, Jing Fu, et al. "Eggshell Quality Traits and Transcriptome Gene Screening Between Yunnong and Jingfen Chicken Breeds." Biology 13, no. 12 (2024): 1048. https://doi.org/10.3390/biology13121048.

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The eggshell quality traits in avian species, including Yunnong chickens (YN), are crucial for commercial and breeding purposes. The use of advanced biotechnologies, such as gene sequencing, has become increasingly common for identifying genetic markers and comparing specific traits in livestock. However, genetic markers related to eggshell traits in YN chickens remain unexplored. This study aimed to compare eggshell quality traits and identify genetic markers in YN chickens versus commercial Jingfen chickens (JF). A total of 400 chicks (200 per breed) were reared for 300 days under controlled
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Assefa, Awraris Derbie, Seong-Hoon Kim, Vimalraj Mani, Hyoung-Rai Ko, and Bum-Soo Hahn. "Metabolic Analysis of the Development of the Plant-Parasitic Cyst Nematodes Heterodera schachtii and Heterodera trifolii by Capillary Electrophoresis Time-of-Flight Mass Spectrometry." International Journal of Molecular Sciences 22, no. 19 (2021): 10488. http://dx.doi.org/10.3390/ijms221910488.

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The cyst nematodes Heterodera schachtii and Heterodera trifolii, whose major hosts are sugar beet and clover, respectively, damage a broad range of plants, resulting in significant economic losses. Nematodes synthesize metabolites for organismal development and social communication. We performed metabolic profiling of H. schachtii and H. trifolii in the egg, juvenile 2 (J2), and female stages. In all, 392 peaks were analyzed by capillary electrophoresis time-of-flight mass spectrometry, which revealed a lot of similarities among metabolomes. Aromatic amino acid metabolism, carbohydrate metabol
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Haqberdiyeva, Mohinur Xo'jaberdi qizi, and Zamira Azimovna Satimova. "THE IMPORTANCE OF VITAMINS N, P AND C IN THE HUMAN BODY BASED ON THE INTEGRATION OF THE NATURAL SCIENCES." "Science and Innovation" international scientific journal 1, no. 1 (2022): 858–69. https://doi.org/10.5281/zenodo.6539301.

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<em>Vitamins are of vital biological importance to all living organisms in nature. Therefore, the composition, structure, processes, functions and use of vitamins are important. This is because vitamins and the micro and macro compounds they contain are involved in the body&#39;s absorption and metabolism. To date, more than 30 types of such vitamins have been identified and studied. The largest group of such vitamins is B vitamins. Of the B vitamins, vitamin B1 contains several trace elements, such as C, N, and O. The micro and macro elements in vitamin B1 are involved in performing the neces
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Liu, Xiyue, Guangtian Cao, Kaifan Qiu, Yingkun Dong, and Caihong Hu. "Lactobacillus plantarum Decreased Ammonia Emissions through Modulating Cecal Microbiotain Broilers Challenged with Ammonia." Animals 13, no. 17 (2023): 2739. http://dx.doi.org/10.3390/ani13172739.

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Probiotic supplementation has become a prominent method of decreasing ammonia emissions in poultry production. The present study was conducted to investigate the influence of Lactobacillus plantarum on ammonia emission, immune responses, antioxidant capacity, cecal microflora and short chain fatty acids, and serum metabolites in broilers challenged with ammonia. A total of 360 1-day-old yellow-feathered broilers were randomly divided into three treatment groups: birds fed with a basal diet (CON), a basal diet supplemented with ammonia (AN), and a basal diet supplemented with 2.5 × 108 CFU L. p
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Dissertations / Theses on the topic "Purine and thiamine metabolism"

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Black, Duncan Arthur. "Aspects of purine and pyrimidine metabolism." Doctoral thesis, University of Cape Town, 1989. http://hdl.handle.net/11427/26590.

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In Chapter 1 a review of the literature concerning aspects of erythrocyte membrane transport and metabolism, and purine and pyrimidine metabolism is presented. The effects of pH, pO₂ and inorganic phosphate (Pi) on the uptake and metabolism of hypoxanthine by erythrocytes has been studied in Chapter 2. Uptake of hypoxanthine and accumulation of inosine 5'-monophosphate (IMP) were markedly increased at acid pH, high external phosphate concentrations, and low pO₂. Release of accumulated IMP as hypoxanthine occurred at alkaline pH values and low external phosphate concentrations. Conditions favou
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Alexiou, Maria. "Purine metabolism in the mouse preimplantation embryo." Thesis, University of York, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317658.

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Byrne, Kerry. "Genetic analysis of thiamine metabolism in Saccharomyces cerevisiae." Thesis, University of Leicester, 1998. http://hdl.handle.net/2381/30304.

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A genetic analysis of thiamine metabolism has been carried out in the budding yeast, Saccharomyces cerevisiae. A collection of thiamine auxotrophic mutants were isolated following UV and Ty insertion mutagenesis. The mutations responsible for the auxotrophic phenotypes were characterised to different extents through complementation analysis, molecular cloning and enzyme assays. In total 171 mutants were analysed and all of these have been assigned to complementation groups, genes and/or functions. Some newly isolated mutations were found to be allelic with the known biosynthetic genes, THI4 an
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Zhang, Fang. "Dysfunctional thiamine metabolism in experimental diabetes and pharmokinetic modelling." Thesis, University of Warwick, 2013. http://wrap.warwick.ac.uk/55352/.

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A dietary-independent thiamine deficiency has been found in experimental and clinical diabetes. Decreased tissue availability of thiamine due to its increased renal clearance is associated with the development of diabetic nephropathy and possibly other microvascular complications of diabetes. Increased thiamine clearance in diabetes is caused by impaired renal reuptake of thiamine. It is proposed that tissue-specific thiamine deficiency may occur in diabetes at sites of complications development – kidney retina and peripheral nerve. The aim of this project was to investigate the involvement of
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Sharma, Ravi Janak. "Uptake and metabolism of circulating inosine and adenosine in the rat." Thesis, St George's, University of London, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295171.

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Navarro, Darren. "Region-selective effects of thiamine deficiency on cerebral metabolism in pyrithiamine-treated rats." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115904.

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Pyrithiamine-induced thiamine deficiency in rats is a well-established animal model of Wernicke's Encephalopathy (WE). This thesis project, submitted as four articles, presents an examination of metabolic events that contribute to the selective neuronal lesions observed in the medial thalamus (MT) of thiamine-deficient (TD) rat. In addition, the phenomenon of glucose-precipitated worsening of neurological status in WE patients (Wallis et al., 1978; Watson et al., 1981) is explored.<br>Lactate accumulation is known to occur selectively in regions of the TD brain, which ultimately express neuron
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Stow, Ruth Anne. "Purine nucleoside transport and metabolism across the rat small intestine." Thesis, University of York, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258382.

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Wolfe, Kara. "The Role of Purine Nucleotide Metabolism in Renal Cell Carcinoma Migration." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563872926565308.

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Rolle, Rosa Sonya. "Isolation and characterization of enzymatic activity mediating cytokinin and purine metabolism in tomato fruit /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487585645577558.

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Hassan, H. F. "Purine and pyrimidine metabolism of Leishmania mexicana mexicana and other parasitic protozoa." Thesis, University of Glasgow, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234859.

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Books on the topic "Purine and thiamine metabolism"

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Harkness, R. Angus, Gertrude B. Elion, and Nepomuk Zöllner, eds. Purine and Pyrimidine Metabolism in Man VII. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-7703-4.

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Sahota, Amrik, and Milton W. Taylor, eds. Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2584-4.

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Griesmacher, Andrea, Mathias M. Müller, and Peter Chiba, eds. Purine and Pyrimidine Metabolism in Man IX. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5381-6.

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Nyhan, W. L., L. F. Thompson, and R. W. E. Watts, eds. Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2.

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Harkness, R. Angus, Gertrude B. Elion, and Nepomuk Zöllner, eds. Purine and Pyrimidine Metabolism in Man VII. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-2638-8.

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Mikanagi, Kiyonobu, Kusuki Nishioka, and William N. Kelley, eds. Purine and Pyrimidine Metabolism in Man VI. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5673-8.

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Mikanagi, Kiyonobu, Kusuki Nishioka, and William N. Kelley, eds. Purine and Pyrimidine Metabolism in Man VI. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5676-9.

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Nyhan, W. L., L. F. Thompson, and R. W. E. Watts, eds. Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5104-7.

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Zoref-Shani, Esther, and Oded Sperling, eds. Purine and Pyrimidine Metabolism in Man X. Springer US, 2002. http://dx.doi.org/10.1007/b113056.

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Andrea, Griesmacher, Chiba Peter, Müller Mathias M, European Symposium on Purine and Pyrimidine Metabolism in Man (6th : 1997 : Gmunden, Austria), and International Symposium on Purine and Pyrimidine Metabolism in Man (9th : 1997 : Gmunden, Austria), eds. Purine and pyrimidine metabolism in man IX. Plenum Press, 1998.

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Book chapters on the topic "Purine and thiamine metabolism"

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Thurston, Jean Holowach, Richard E. Hauhart, John A. Dirgo, and David B. McDougal. "Thiamine Deficiency." In Cerebral Energy Metabolism and Metabolic Encephalopathy. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1209-3_15.

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Ashihara, Hiroshi, Shinjiro Ogita, and Alan Crozier. "Purine Alkaloid Metabolism." In Plant Metabolism and Biotechnology. John Wiley & Sons, Ltd, 2011. http://dx.doi.org/10.1002/9781119991311.ch6.

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Sperling, O. "Human Purine Metabolism." In Developments in Cardiovascular Medicine. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1319-6_20.

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Braun-Falco, Otto, Gerd Plewig, Helmut H. Wolff, and Richard K. Winkelmann. "Disorders of Purine Metabolism." In Dermatology. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-662-00181-3_47.

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Wolberg, G. "Antipurines and Purine Metabolism." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73217-1_24.

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Braun-Falco, Otto, Gerd Plewig, Helmut H. Wolff, and Walter H. C. Burgdorf. "Disorders of Purine Metabolism." In Dermatology. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-97931-6_47.

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Saudubray, J. M. "Inborn Errors of Thiamine Metabolism." In Inborn Metabolic Diseases. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-662-02613-7_49.

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Souza, Paulo Victor Sgobbi, Paulo de Lima Serrano, Wladimir Bocca Vieira de Rezende Pinto, Igor Braga Farias, and Acary Souza Bulle Oliveira. "Thiamine Metabolism Dysfunction Syndrome (THMD)." In Genetic Syndromes. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-319-66816-1_1799-1.

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Greger, R. "Purine Excretion." In Genetic and Therapeutic Aspects of Lipid and Purine Metabolism. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-61322-7_8.

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Stone, T. W., and H. A. Simmonds. "Tissue specificity of purine metabolism." In Purines: Basic and Clinical Aspects. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3911-3_3.

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Conference papers on the topic "Purine and thiamine metabolism"

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Zborovsky, AB, MY Stazharov, VF Martemyanov, SA Bedina, EE Mozgovaya, and TP Chernykh. "SAT0047 Purine metabolism and antioxidant system in osteoarthritis." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.422.

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Privalova, Tatiana, Tatiana Privalova, Iuliia Khen, et al. "PP-116 Diagnosis of purine metabolism disorders in children." In 11th Europaediatrics Congress, Antalya, Türkiye, 17 – 21 April 2024. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/bmjpo-2024-epac.260.

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Caligola, Simone, Tommaso Carlucci, Franco Fummi, et al. "Automatic Parameterization of the Purine Metabolism Pathway through Discrete Event-based Simulation." In 2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB). IEEE, 2019. http://dx.doi.org/10.1109/cibcb.2019.8791471.

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ZZborovsky, AB, VF Martemyanov, MY Stazharov, SA Bedina, TP Chernykh, and EE Mozgovaya. "AB0024 Activities of purine metabolism enzymes and antioxidant system in rheumatoid arthritis patients." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.929.

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Basha, Nour, Hazem N. Nounou, and Mohamed N. Nounou. "Application of a fuzzy learning intervention approach to a purine metabolism pathway model." In 2014 Middle East Conference on Biomedical Engineering (MECBME). IEEE, 2014. http://dx.doi.org/10.1109/mecbme.2014.6783233.

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An, Songon. "Abstract B13: Akt-independent PDK1 signaling in regulation of purine biosynthesis." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-b13.

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Auziņš, Ernests Tomass. "Kā raugs uzvedas, kad tam atņem būvelementus?" In LU Studentu zinātniskā konference "Mundus et". LU Akadēmiskais apgāds, 2021. http://dx.doi.org/10.22364/lu.szk.2.rk.02.

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The study explored changes in carbon fluxes in the central metabolism of brewer’s yeast in the absence of building blocks such as adenine or nitrogen. These flows provide insight into changes in the central metabolism of brewer’s yeast. It was found that in the absence of a building block, the yeast mainly uses fermentation for growth, producing ethanol. Deletion of Δade1 in purine de novo synthesis reduces ethanol production, and decreased glycerol production in adenine starvation indicates a slowing of central metabolism.
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Gottlieb, Eyal. "Abstract IA06: De novo purine biosynthesis dictates glutamine dependency of glioblastoma cells." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-ia06.

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Siqueira, Fernando, Vanessa Siqueira, Lucas Falcão, Arthur Bezerra, and Carlos Silva. "THE INFLUENCE BETWEEN ALZHEIMER’S DISEASE AND HEALTHY EATING: A SYSTEMATIC REVIEW." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda062.

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Background: Alzheimer’s Disease (AD) is a neurodegenerative disease responsible for neuronal losses that affect mainly the cortex and hippocampus, which begin to shrink in size, damaging cognitive functions. This process affects cholinergic neurons, influencing acetylcholine (ACH) levels, a memoryrelated neurotransmitter. Glucose metabolism and low thiamine levels appear to be affected by AD. Consequently, diabetes becomes a disease associated with AD and the thiamine deficiency levels depress the use of glucose by the brain. Thus, nutrition may have a role in preventing dementia through the t
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Mozgovaya, E., A. Trofimenko, S. Bedina, and I. Zborovskaya. "AB0872 Diagnostic efficiency of determining the purine metabolism enzymes activity in the differentiation of gout." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2304.

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Reports on the topic "Purine and thiamine metabolism"

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MARTEMYANOV, V. F., S. A. BEDINA, E. E. MOZGOVAYA, O. D. KOROLIK, and I. A. ZBOROVSKAYA. THE CLINICAL DIAGNOSTIC VALUE OF A STUDY OF THE ACTIVITY OF ENZYMES OF THE PURINE METABOLISM IN PATIENTS WITH RHEUMATOID ARTHRITIS. SCIENTIFIC JOURNAL, 2016. http://dx.doi.org/10.18411/ijafr.2016.7.6.979.

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