Academic literature on the topic 'PVP K30'

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Journal articles on the topic "PVP K30"

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Shete, Nikhil Arun, Vishwajeet M. Swami, Avinash Chaudhari, and Prachi N. Khabiya. "A Design of Experiment Approach for Optimization and Characterization of Clarithromycin Ternary System Using Spray Drying." Journal of Drug Delivery and Therapeutics 10, no. 3-s (2020): 211–20. http://dx.doi.org/10.22270/jddt.v10i3-s.4185.

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The aim of present work was to characterize Clarithromycin (CLT), Polyvinyl pyrrolidone K30 (PVP K30) and Hydroxypropyl β-cyclodextrin (HPB) ternary system so as to check the effect of complexation on solubility of CLT. Physical mixtures of a drug and polymers in several weight ratios (1:1, 1:2) were prepared to check the effect of individual polymers on solubility of CLT. Spray drying method was accustomed investigate the combined effect of PVP K30 and HPB on Drug release (DR), Dissolution efficiency (DE) and mean dissolution time (MDT) of CLT. For the preparation and optimization of ternary
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2

Shaikh, Amir A., Praveen D. Chaudhari, and Sagar S. Holkar. "A DESIGN OF EXPERIMENT APPROACH FOR OPTIMIZATION AND CHARACTERIZATION OF ETODOLAC TERNARY SYSTEM USING SPRAY DRYING." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 2 (2017): 233. http://dx.doi.org/10.22159/ijpps.2017v9i2.16087.

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<p><strong>Objective: </strong>The objective of the present investigation was to prepare and characterize Etodolac (ETO), Polyvinyl pyrrolidone K30 (PVP K30) and Hydroxypropyl β-cyclodextrin (HPB) ternary system in order to study the effect of complexation on solubility of ETO.</p><p><strong>Methods: </strong>Physical mixtures of a drug and polymers in different weight ratios (1:1, 1:2, 1:4) were prepared to study the effect of individual polymers on solubility of ETO. Spray drying method was used to investigate the combined effect of PVP K30 and HPB o
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3

Maheswari, K. M., Pavan Kumar Devineni, Sravanthi Deekonda, Salma Shaik, Naga Pravallika Uppala, and Buchi N. Nalluri. "Development and Evaluation of Mouth Dissolving Films of Amlodipine Besylate for Enhanced Therapeutic Efficacy." Journal of Pharmaceutics 2014 (March 27, 2014): 1–10. http://dx.doi.org/10.1155/2014/520949.

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The present investigation was undertaken with an objective of formulating mouth dissolving films (MDFs) of Amlodipine Besylate (AMLO) to enhance convenience and compliance of the elderly and pediatric patients for better therapeutic efficacy. Film formers like hydroxy propyl methyl cellulose (HPMC) and methyl cellulose (MC) along with film modifiers like poly vinyl pyrrolidone K30 (PVP K30), and sodium lauryl sulphate (SLS) as solubilizing agents were evaluated. The prepared MDFs were evaluated for in vitro dissolution characteristics, in vitro disintegration time, and their physicomechanical
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Lu, Min, Wei Wei, Wenhao Xu, Nikolay E. Polyakov, Alexandr V. Dushkin, and Weike Su. "Preparation of DNC Solid Dispersion by a Mechanochemical Method with Glycyrrhizic Acid and Polyvinylpyrrolidone to Enhance Bioavailability and Activity." Polymers 14, no. 10 (2022): 2037. http://dx.doi.org/10.3390/polym14102037.

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To exploit aqueous-soluble formulation and improve the anticoccidial activity of 4,4′-dinitrocarbanilide (DNC, active component of nicarbazin), this paper prepared DNC/GA/PVP K30 solid dispersion (SD) with glycyrrhizic acid (GA) and polyvinylpyrrolidone (PVP) K30 by a mechanical ball milling method without using any organic solvent. Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, and scanning electron microscopy were used for the solid state characterization. High performance liquid chromatography, critical micelle concentration, particle characte
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Wang, Jie Liang, Ai Juan Gu, and Guo Zheng Liang. "Modification of Bisphenol A Dicyanate Ester Resin with Poly Vinyl Pyrrolidone (K30)." Advanced Materials Research 217-218 (March 2011): 1497–503. http://dx.doi.org/10.4028/www.scientific.net/amr.217-218.1497.

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Poly vinyl pyrrolidone (PVP(K30)) / Bisphenol A Dicyanate ester (BADCy) blends were fabricated to increase the toughness of BADCy by blending processing in this paper. Curing parameters were determined by gelation time curves and differential scanning calorimetry (DSC) of the systems. Fourier transform infrared spectrometry (FTIR) and DSC data were employed to show the curing behavior and kinetics of the systems. Mechanical properties of the cured resin had been improved rapidly with the increasing of PVP(K30) at low mass fraction, but would decrease when mass fractions of PVP(K30) were higher
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6

Noval, Noval, and Rosyifa Rosyifa. "SOLID DISPERSION FOR INCREASING DISSOLUTION RATE OF SODIUM DICLOFENAC WITH VARIATIONS OF POLYVINYL PYRROLIDONE K30." Journal of Pharmaceutical Care Anwar Medika 3, no. 2 (2021): 86–98. http://dx.doi.org/10.36932/jpcam.v3i2.46.

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Diclofenac sodium is included in class II category based on biopharmaceutics classification system (BCS), sodium diclofenac has low solubility and high permeability. Low solubility will affect absorption of drugs in body because rate of dissolution will decrease. PVP K30 is inert carrier that dissolves easily in water and can affect solubility of an active drug substance. To know solid dispersion system increasing dissolution rate of sodium diclofenac by adding variations concentration of PVP K30. Solid dispersion uses solvent method with variations concentration of PVP K30 1:3, 1:5, 1:7 and 1
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7

Kotia, Ankit, Sunil More, Aman Yadav, et al. "Rheological Properties and Its Effect on the Lubrication Mechanism of PVP K30 and PVP 40-50 G as Artificial Synovial Fluids." Inventions 6, no. 4 (2021): 61. http://dx.doi.org/10.3390/inventions6040061.

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The effect of polyvinylpyrrolidone (PVP) on the rheological properties of joint prostheses is still unclear, despite its good lubricity and biocompatibility. In the present work, PVP K30 and PVP 40-50 G solutions at different concentrations were analyzed for rheological and lubrication properties. The rheological properties of the samples were measured at a shear rate range of 0–1800 s−1 (advanced air bearing rheometer Bohlin Gemini 2 and Plate MCR 72/92 rheometer for PVP30 and PVP 40-50 G, respectively). It was found that both the viscosity and shear stress of the samples reduced with a shear
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8

Noval, Noval, and Rosyifa Rosyifa. "Dispersi Padat untuk Peningkatan Laju Disolusi Natrium Diklofenak dengan Variasi Konsentrasi Polivinil Pirolidon K30." Jurnal Surya Medika 6, no. 2 (2021): 94–101. http://dx.doi.org/10.33084/jsm.v6i2.2125.

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Diclofenac sodium is included in the class II category based on the biopharmaceutics classification system (BCS), sodium diclofenac has low solubility and high permeability. Low solubility will affect the absorption of drugs in the body because the rate of dissolution will decrease. Polyvinyl Pyrrolidone (PVP) K30 is an inert carrier that dissolves easily in water and can affect the solubility of an active drug substance. To know solid dispersion system increasing dissolution rate of sodium diclofenac by adding variations concentration of PVP K30. Solid dispersion uses a solvent method with va
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9

Liu, Luan, Jin Hu, Yu Tian Wang, Kai Jun Wang, and Lin Su. "Preparation of Sub-Micrometre Size Platinum Particles via Chemical Reduction of Hexachloroplatinic Acid in Aqueous Solution." Advanced Materials Research 1058 (November 2014): 48–51. http://dx.doi.org/10.4028/www.scientific.net/amr.1058.48.

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The sub-micrometre size platinum particles via chemical reduction of hexachloroplatinic acid in aqueous solution was investigated by UV-Visible Spectroscopy, Transmission Electron Microscopy, X-ray diffraction and FTIR Spectroscopy. Hydrazine hydrate was used as the reducing agent, and polyvinylpyrrolidone (PVP-K30) was used for stabilizing the particles. By varying the amount of PVP-K30 the average diameter of the platinum particles could be adjusted. The TEM and XRD results revealed that the final sub-micrometre size Pt particles were the result of an aggregation of small (~5 nm) nanoparticl
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10

Zhu, Wei-Feng, Lin Zhu, Zhe Li, et al. "The Novel Use of PVP K30 as Templating Agent in Production of Porous Lactose." Pharmaceutics 13, no. 6 (2021): 814. http://dx.doi.org/10.3390/pharmaceutics13060814.

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It is necessary to prepare porous lactose in order to improve the dissolution behavior of insoluble active ingredient. In this study, polyvinylpyrrolidone K30 (PVP K30) was firstly utilized as a templating agent with different use levels in preparing porous lactose. Then, the physical properties were profoundly characterized. Finally, the porous lactose was also employed as a health functional food/drug carrier to explore the effect on the dissolution behavior of curcumin. The results confirmed that (i) porous lactose was successfully prepared using PVP K30 as templating agent; (ii) PVP K30 si
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Books on the topic "PVP K30"

1

1964-, Bens Paul G., ed. Next!: An actor's guide to auditioning. Lone Eagle Pub. Co., 1997.

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Alta.) WIN (Conference) (2nd 2011 Banff. Women in Numbers 2: Research directions in number theory : BIRS Workshop, WIN2 - Women in Numbers 2, November 6-11, 2011, Banff International Research Station, Banff, Alberta, Canada. Edited by David Chantal 1964-, Lalín Matilde 1977-, and Manes Michelle 1970-. American Mathematical Society, 2013.

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Book chapters on the topic "PVP K30"

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Bejaoui, Marouene, Hanen Oueslati, and Haykel Galai. "Ternary Solid Dispersion Strategy for Solubility Enhancement of Poorly Soluble Drugs by Co-Milling Technique." In Chitin and Chitosan - Physicochemical Properties and Industrial Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95518.

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Amorphous ternary solid dispersion has become one of the strategies commonly used for improving the solubility and bioavailability of poorly water soluble drugs. Such multicomponent solid dispersion can be obtained by different techniques, this chapter provides an overview of ternary solid dispersion by co-milling method from the perspectives of physico-chemical characteristics in vitro and in vivo performance. A considerable improvement of solubility was obtained for many active pharmaceutical ingredients (e.g., Ibuprofen, Probucol, Gliclazid, Fenofibrate, Ibrutinib and Naproxen) and this was
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