Relevant bibliographies by topics / Quinazolinon

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Quinazolinon'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Quinazolinon"

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Asif, Mohammad. "Chemical Characteristics, Synthetic Methods, and Biological Potential of Quinazoline and Quinazolinone Derivatives." International Journal of Medicinal Chemistry 2014 (November 13, 2014): 1–27. http://dx.doi.org/10.1155/2014/395637.

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The heterocyclic fused rings quinazoline and quinazolinone have drawn a huge consideration owing to their expanded applications in the field of pharmaceutical chemistry. Quinazoline and quinazolinone are reported for their diversified biological activities and compounds with different substitutions bring together to knowledge of a target with understanding of the molecule types that might interact with the target receptors. Quinazolines and quinazolinones are considered as an important chemical for the synthesis of various physiological significance and pharmacological utilized molecules. Quin
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Abu-Hashem, Ameen. "Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity." Molecules 23, no. 11 (2018): 2793. http://dx.doi.org/10.3390/molecules23112793.

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Substituted-6-methyl-1-thioxo-1,2-dihydro-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-ones (5a,b) were synthesized from condensation of visnagenone (2a) or khellinone (2b) with 6-amino-thiouracil (3) in dimethylformamide or refluxing of (4a) or (4b) in dimethylformamide. Hence, compounds (5a,b) were used as the starting materials for preparing many new heterocyclic compounds such as; furo[3,2-g]pyrimido[1,6-a]quinazoline (6a,b), furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazolinone (7a,b), substituted-benzylidene-furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazoline-3,5-dione (8a–f), 3-o
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R., S. VARMA, and PREETI GUPTA (Miss). "Nucleophilic Reactions of 2-Methyl-3-( 4' -carbomethoxyphenyl)-4-quinazolinones with 2-lndolinones." Journal of Indian Chemical Society Vol. 66, Nov 1989 (1989): 804–5. https://doi.org/10.5281/zenodo.6090915.

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Department of Chemistry, Lucknow University, Lucknow-226 007 <em>Manuscript received 10 March 1989, accepted 20 June 1989</em> 2-Methyl-3-(4&#39;-carbomethoxphenyl)-4-quinazolinone undergoes nucleophilic addition-elimination reactions with different lndolinones leading to 2-(3-methylene- substituted-oxindolyl)-3-(4&#39;-carbomethoxyphenyl)-4-quinazolinones (2a- e), Similarly, <em>N</em>-methylindolinones react with 2-methyl-3-(4&#39;-carbomethoxyphenyl)-4-quinazolinone to give 2- (3-methylene-1- methyl-substituted -oxindolyl)- 3 -( 4&#39; - carbomethoxyphenyl)-4 quinazolinones (4a -e). Mannich
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S, G. ABDEL-HAMIDE. "Synthesis of some New Heterocyclic Systems bearing 2-Phenyl-6-iodo-4(3H)-quinazolinon-3-yl Moiety as Antibacterial Agents." Journal of Indian Chemical Society Vol. 74, Aug 1997 (1997): 613–18. https://doi.org/10.5281/zenodo.5891302.

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Pharmaceutical Chemistry Department, Al-Azhar University, Cairo, Nasr City, Egypt <em>Manuscript received 6 March 1995, revised 18 March 1996, accepted 24 July 1996</em> A number of heterobicyclic systems bearing 2-phenyl-6-iodo-4(3<em>H</em>)-quinazolinon-3-yl moiety have been synthesised by interaction of 3- amino-2-phenyl-6-iodo-4(3<em>H</em>)-quinazolinone with bifunctional compounds followed by cyclisation in different media. Some of the compounds possess high activity aganist bacteria.
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Deng, Zhijiang, Jieming Li, Pengbo Zhu, et al. "Quinazolinones as Potential Anticancer Agents: Synthesis and Action Mechanisms." Biomolecules 15, no. 2 (2025): 210. https://doi.org/10.3390/biom15020210.

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Quinazolinones, essential quinazoline derivatives, exhibit diverse biological activities with applications in pharmaceuticals and insecticides. Some derivatives have already been developed as commercial drugs. Given the rising cancer incidence, there is a critical need for new anticancer agents, and quinazolinones show promising potential in this domain. The present review focuses on novel advances in the synthesis of these important scaffolds and other medicinal aspects involving drug design, the structure–activity relationship, and action mechanisms of quinazoline and quinazolinone derivativ
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Starikova, Alla Andreevna, Alexandra Aleksandrovna Tsibizova, and Marina Aleksandrovna Samotrueva. "BIOLOGICAL ACTIVITY OF NATURAL QUINAZOLINE ALKALOIDS." Chemistry of plant raw material, no. 2 (May 4, 2025): 47–73. https://doi.org/10.14258/jcprm.20250214908.

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To date, quinazoline alkaloids of natural origin, as well as synthetic derivatives based on them, whose structure contains an aromatic heterocyclic system including a pyrimidine cycle and a benzoin ring connected to it, are promising according to the criterion of the optimal profile of pharmacological activity. Currently, several hundred compounds of the quinazoline nature have been identified with a wide range of biological activities, including psychotropic (antidepressant, antipsychotic, sedative, hypnotic, anticonvulsant, etc.), antiplatelet, hypotensive, anti-inflammatory, antioxidant and
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Khachatryan, D. S., V. A. Misyurin, M. A. Baryshnikova, N. V. Golubtsova, A. V. Kolotaev, and K. R. Matevosyan. "Quinazolinon derivatives for the treatment of neoplastic, parasitic and neurodegenerative diseases." Russian Journal of Biotherapy 16, no. 3 (2017): 32–42. http://dx.doi.org/10.17650/1726-9784-2017-16-3-32-42.

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In this review we discuss some biological activities of quinazolinon derivatives. The derivatives of quinazolinon possess their activity by binding to some proteins important for the survival, proliferation and metastasis of tumor cells. There are grounds to initiate clinical trials of these substances to create new treatment protocols for a wide range of cancer diseases, several parasitic diseases, and certain neurodegenerative diseases.
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Peter Osarodion Osarumwense, Mary Olire Edema, and Cyril Odianosen Usifoh. "Synthesis and antibacterial activities of quinazolin-4(3h)-one, 2-methyl-4(3h)-quinazolinone and 2–phenyl-4(3h)-quinazolinone." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (2021): 077–84. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0027.

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Background: Quinazoline and quinazolinone scaffolds represent an important class of biologically active nitrogen heterocyclic compounds. Many marketed drugs are based on these moieties. A diverse range of molecules with quinazoline/quinazolinone moieties have been reported to exhibit broad spectrum of biological activities Objective: This study is aimed at the synthesis of these quinazolinone derivatives, quinazolin-4(3H)-One, 2-Methyl-4(3H)-quinazolinone and 2–Phenyl-4(3H)-quinazolin-4(3H)–one and evaluate them for their antibacterial activities. Method: The consolidation of 2-amino-methyl-4-
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Vishwakarma, Lav Kush Kumar, and Varsha Kashaw. "Nanocatalyzed Synthetic Approach for the Quinazolinone and Quinazoline Derivatives: A Review (2015 – Present)." Journal of Drug Delivery and Therapeutics 13, no. 3 (2023): 171–83. http://dx.doi.org/10.22270/jddt.v13i3.5765.

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Due to their diverse chemical reactivities and essential range of biological action, quinazolines and their derivatives rank among the most significant heterocyclic compounds. Quinazoline and quinazolinone scaffolds pharmacological properties have sparked medicinal chemists' interest in creating original medications or drug candidates. The growth of quinazoline hybrid lead compounds and the related heterocycles is summarised in the current review of medicinal chemistry. Additionally, by shedding light on the potential significance of these hybridised pharmacophoric characteristics in the demon
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Jianghong, Man, Qi Jianbin, Jiang Jie, and Li Sha. "Microwave Reaction Improved Heterocyclization of Quinazolinone Ring in Synthesis of Erlotinib Analogues." Journal of Pharmaceutical and Biomedical Sciences 10, no. 05 (2020): 99–105. https://doi.org/10.1234/zenodo.3876.

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Background Tinibs were a kind of important epidermal growth factor receptor (EGFR) inhibitors used as potential therapeutic agents in treating non-small cell lung cancer (NSCLC) in clinic. The drug resistance of clinical used tinibs made the development of more active tinib analogues an attractive field in research. Quinazoline ring was regarded as the key fragment in tinibs and quinazolinone was indispensible intermediate in the synthesis of quinazoline. Thus, synthesis of quinazolinone intermediates was a key step which would further limit the overall yield of final product of tinib analogue
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Dissertations / Theses on the topic "Quinazolinon"

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Soledade, Cinira Santana. "O efeito do DMA (composto quinazolinico) sobre o processo inflamatorio." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310436.

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Orientadores: Lilian Tereza Lavras Costallat, Kleber Gomes Franchini<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-13T01:28:13Z (GMT). No. of bitstreams: 1 Soledade_CiniraSantana_D.pdf: 1680992 bytes, checksum: 98f3f468653137a8796c59f9d6297f89 (MD5) Previous issue date: 2008<br>Resumo: A inflamação é apontada como o principal processo mediador das diversas doenças do tecido conjuntivo e um componente importante da fisiopatologia das doenças infecciosas. Mais recentemente também tem lhe sido atribuído papel de des
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Oliveira, Andre Nazario de. "Determinação da toxidade in vitro e vivo de compostos quinazolinicos e identificação do acido homovanilico por espectrometria de ressonancia magnetica nuclear de hidrogenio (1 ANTPOT. H)." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311380.

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Orientadores: Nelci Fenalti Hoehr, Roberto Rittner<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-14T17:11:44Z (GMT). No. of bitstreams: 1 Oliveira_AndreNazariode_M.pdf: 1693019 bytes, checksum: c0e1f56be54157760e94e4822c8d9f5f (MD5) Previous issue date: 2009<br>Resumo: Este projeto tem a finalidade de analisar as características toxicológicas de novos compostos quinazolínicos, que foram sintetizados recentemente no Instituto de Química-UNICAMP. Uma série de derivados de 4-fenilamino quinazolinas foi sinteti
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Stein, Tobias. "Radical synthesis of quinazolinone natural products." Thesis, Loughborough University, 2007. https://dspace.lboro.ac.uk/2134/34389.

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Investigations into radical and palladium(0) cyclisations onto the C-2 position of the 3H-quinazolin-4-one moiety have been made. This has led to the syntheses of a number of biologically active quinazolinone natural products using alkyl, heteroaryl and acyl radical cyclisations. The reactions proceeded via a homolytic aromatic substitution mechanism. As such, fully rearomatised products were recovered. A C-2 radical 3H-quinazolin-4-one building block was also prepared. This turned out to have only limited synthetic applications. Radical cyclisations onto aryl groups were carried out using thi
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Dai, Xuedong 1970. "Synthesis and applications of atropisomeric quinazolinone phosphine ligands." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/47887.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1998.<br>Includes bibliographical references.<br>Several novel atropisomeric phosphine ligands have been synthesized and evaluated. The syntheses of 2-methyl-3-[2'-(diphenylphosphino)phenyl]-4(3H)- quinazolinone (la) and its methyl-substituted analogs lb and ic were achieved in good yield by coupling N-acetylanthranilic acid with the corresponding phosphinoanilines 4a-c. A practical resolution of ligands la-c was accomplished using the benzenesulfonylhydrazone derivative (10) of (1S)-(+)-camphorsulfonic acid as a novel
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Skelton, Lorraine Ann. "Pyridyl quinazolines as potential antitumour agents." Thesis, Institute of Cancer Research (University Of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294789.

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Antunes, João Eustáquio 1971. "Novas quinazolinas 2,4,8-dissubstituídas com potencial atividade de inibição da quinase de adesão focal (FAK)." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310204.

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Orientador : Kleber Gomes Franchini<br>Tese (Doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-22T00:30:15Z (GMT). No. of bitstreams: 1 Antunes_JoaoEustaquio_D.pdf: 5472161 bytes, checksum: d84f6389e6baf3e2959126f6345e6a14 (MD5) Previous issue date: 2013<br>Resumo: A compreensão de como a quinase de adesão focal (FAK) contribui para os processos de hipertrofia, insuficiência cardíaca e câncer são de grande interesse científico. Um dos nossos objetivos específicos é desenvolver inibidores desta tirosina quinase com vistas à su
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Cabeça, Luis Fernando. "Sintese e caracterização de novas quinazolinas polissubstituidas." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249190.

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Orientador: Roberto Rittner Neto<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-04T06:03:33Z (GMT). No. of bitstreams: 1 Cabeca_LuisFernando_M.pdf: 1975503 bytes, checksum: 3a2b7f9645f9f796cf137706d965ae5c (MD5) Previous issue date: 2004<br>Mestrado<br>Quimica Organica<br>Mestre em Química
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Jaeda, Mousa I. "The synthesis of 2-quinazolinones and homologues." Thesis, Aston University, 1985. http://publications.aston.ac.uk/12495/.

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Desroses, Matthieu. "Conception, synthèse et évaluation pharmacologique d'aminoquinazolines, inhibiteurs potentiels d'activités tyrosine kinases." Lille 2, 2005. http://www.theses.fr/2005LIL2S026.

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La famille des récepteurs de facteur de croissance ErbB/HER est constituée de quatre récepteurs transmembranaires codés par les protooncogènes c-erbB-1/HER/EGFR, c-erbB-2/neu/HER-2, c-erbB-3/HER-3, c-erbB-4/HER-4. Ces récepteurs sont impliqués dans une grande variété de processus physiologiques cellulaires mais sont également associés à diverses pathologies, y compris le Cancer. Les voies de signalisation de l'EGFR jouent un rôle dans beaucoup d'aspects de la biologie des cellules tumorales et la surexpression de l'EGFR est rapportée dans un certain nombre de lignées cancéreuses humaines. En e
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Norrie, R. "The synthesis and reactions of sulphur analogues of deoxyvasicinone." Thesis, University of Abertay Dundee, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233850.

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Books on the topic "Quinazolinon"

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Brown, D. J. Quinazolines. Wiley, 1996.

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Feldmann, Burkhard. Darstellung und spektroskopische Eigenschaften neuer H-Chelate der Chinazolinreihe. Hartung-Gorre, 1986.

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Jaeda, Mousa Ibrahim. The synthesis of 2-quinazolinones and homologues. University of Aston. Department of Pharmaceutical Sciences, 1985.

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Gamal Al-kaf, Ali, ed. Quinazolinone and Quinazoline Derivatives. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.85315.

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Brown, Desmond J. Quinazolines, Supplement 1. Wiley & Sons, Incorporated, John, 2007.

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Brown, Desmond J. Quinazolines, Supplement 1. Wiley & Sons, Incorporated, John, 2009.

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Joshi, B. L. Some studies with quinazolines and related compounds. 1985.

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Quinoxalines. Wiley, 2004.

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Qualmann, Christiane. Multidrug-resistente menschliche lymphoblastoide T-Zellinien als Modell zur Charakterisierung des Kreuzresistenzverhaltens neuer Zytostatika: Untersuchung von Quinazolin- und Anthrapyrazol-Derivaten. 1992.

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Book chapters on the topic "Quinazolinon"

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Takasugi, J. J., L. A. Witucki, D. J. France, L. S. Evans, C. L. Kohls, and M. V. Neypes. "Novel and Selective Quinazolinyl Arylureas." In ACS Symposium Series. American Chemical Society, 1995. http://dx.doi.org/10.1021/bk-1995-0584.ch033.

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Singh, Vinay Kumar, Anjani Kumar Tiwari, and Mohd Faheem. "Synthetic Approach of Quinazolines Candidates." In N-Heterocycles. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0832-3_8.

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Barker, A. J., L. R. Hughes, P. Warner, K. Burrows, and A. L. Jackman. "Thymidylate Synthase Inhibition of Modified Quinazoline Antifolates." In Cytotoxic Anticancer Drugs: Models and Concepts for Drug Discovery and Development. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3492-1_4.

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Gros, Philippe C. "Other Stoichiometric Metalation Reactions on Pyrimidine and Quinazoline." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_93.

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Kolarovič, Andrej. "Lithiations and Grignard Reactions on Pyrimidine and Quinazoline." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_94.

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Panwar, Vivek, Kritika Mukherji, Manjunath Ghate, Deepak K. Jindal, and Deepak Kumar. "EGFR-Targeted Quinazoline Clubbed Heterocycles as Anticancer Agents." In Biomedical Translational Research. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9232-1_21.

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Dangi, R. R., N. S. Chundawat, and K. L. Ameta. "Synthesis and Biological Evaluation of Some Quinazoline Heterocyclic Derivatives." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_13.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_321.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of manganese(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_56.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of cobalt(II) complex with quinazoline ligand." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_245.

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Conference papers on the topic "Quinazolinon"

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Suong, Lien Kieu, Vo Phung Nguyen, and Trinh Thi Phuong Lan. "ANTI-CONVULSIVE ACTIVITY OF NL197, A DERIVATIVE FROM 4(3H)QUINAZOLINON ON CHEMICAL INDUCED SEIZURE MICE." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00215.

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Laddha, Sachin, and Satyendra Bhatnagar. "Novel Fused quinazolinones: Further studies on the anticonvulsant activity of 1,2,9,11 tetrasubstituted-7H-thieno[2',3':4,5]pyrimido[6,1-b]-quinazolin-7-one and 1,3,10,12- tetrasubstituted-8H-pyrido[2',3':4,5]pyrimido[6,1-b]quinazolin-8-one." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00222.

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Al-Majedy, Yasmien, Ahmed Al-Amiery, and Redha Al-Bayati. "Novel quinazolinone derivatives: Synthesis and Antimicrobial Activity." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00413.

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Seijas, Julio, M. Vazquez-Tato, and M. Martinez. "Microwave Enhanced Synthesis of Quinazolines." In The 3rd International Electronic Conference on Synthetic Organic Chemistry. MDPI, 1999. http://dx.doi.org/10.3390/ecsoc-3-01734.

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Yan, Heping, Jianguang Shi, Gaozhang Gou, et al. "Synthesis of Quinazolinyl Chalcone Derivatives." In 3rd International Conference on Material, Mechanical and Manufacturing Engineering (IC3ME 2015). Atlantis Press, 2015. http://dx.doi.org/10.2991/ic3me-15.2015.61.

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Dolzhenko, Anton, Anna Dolzhenko, and Wai-Keung Chui. "Reaction of 2-guanidino-4-quinazolinone with arylaldehydes." In The 10th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01382.

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Turgunov, Kambarali, and Ulli Englert. "Metal halide coordination compounds with 4(3H)-quinazolinone." In The 2nd International Online Conference on Crystals. MDPI, 2020. http://dx.doi.org/10.3390/iocc_2020-07334.

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Rammohan, Aluru, and Grigory V. Zyryanov. "Synthesis and characterization of 1,2,3-triazole integrated quinazolinone derivatives." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018182.

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Fadil MOUSA, Enaam, and Ibtissam Khalifa JASSIM. "SYNTHESIS ,CHARACTERIZATION AND BIOLOGICAL ACTIVITY STUDY OF SOME HETEROCYCLIC COMPOUNDS." In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-18.

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Heterocycles are an important class of organic compounds because of their applications in medicines and industrial fields. Therefore our study included preparation of these compound such as oxazepine and quinazoline rings, which were prepared through two steps: The first step included the reaction of the Schiff bases derived from sulfamethaxazole (1-4) with each of phthalic anhydride and 3- nitrophthalic anhydride for the preparation of oxazepines (5-12) .While the second step included the preparation of quinazoline compounds (13-16) from the reaction of Schiff bases (1-4) with anthranilic aci
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Guerreiro Souzedo, Gabriela, LJUBICA TASIC, and Caio Henrique Nasi De Barros. "Synthesis of Quinazoline Derivatives for Adenosine Kinase Inhibition." In XXV Congresso de Iniciação Cientifica da Unicamp. Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-78452.

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