Academic literature on the topic 'Quinoxalinon'

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Journal articles on the topic "Quinoxalinon"

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M., Z. A. BADR, A. MAHGOUB S., M. ATTA F., S. MOUSTAFA O., and M. ABO EL-LATIF F. "Synthesis and Chemistry of 3-Amino- and 3-Hydrazocarbonylquinoxalinone Derivatives." Journal of Indian Chemical Society Vol. 71, Oct 1994 (1994): 617–19. https://doi.org/10.5281/zenodo.5896678.

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Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt <em>Manuscript received 4 June 1993, accepted 18 August 1993</em> 3-Ethoxycarbonyl-2(1<em>H</em>)-quinoxalinone (1) reacts with nucleophiles, namely, dimethylamine, diethylamine, <em>o</em>- phenylenediamine and/or p-phenylenediamine to produce the corresponding 3-<em>N</em>-substituted-aminocarbonyl-2(1<em>H)</em>-quinoxalinones (3-6). Treatment of 1 with hydrazine hydrate produces the 2(1<em>H</em>)-quinoxalinone-3-carbohydrazide (2) with acylating reagents, namely, acetic anhydride, acetic acid or acetyl chloride/pyr
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S.D., Trivedi, T. Kubawat H., and H. Parekh H. "Studies on imidazolinone derivatives : synthesis and antimicrobial activity of 1-[2(1H)-quinoxalinon-1 '-ylacetamido ]-2-phenyl/methyl-4-arylidene-5- oxoimidazolines." Journal of Indian Chemical Society Vol.79, Mar 2002 (2002): 282–83. https://doi.org/10.5281/zenodo.5849836.

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Department of Chemistry, Saurashtra University, Rajkot-360 005, India <em>Fax</em> : 091-0281-78512 <em>Manuscript received I I July 200I, accepted 22 August 2001</em> Some new 4-substituted-benzylidene-1-|2(1<em>H</em>)-quinoxalinon-1&#39;-ylacetamido|-2-phenyl/methyl-4-arylidene-5-oxoimidazolines have been prepared by reacting 2-oxaquinoxalin-1-ylacetylhyldrazine with preformed azlactones. The compounds are screened for antibacterial and antifungal activities.
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Lgaz, Hassane, Ali Aldalbahi, and Han-Seung Lee. "Atomic-Level Insights into the Adsorption of Methyl-Substituted Quinoxalinones on Fe(110): A Dispersion-Corrected DFT Analysis." Molecules 29, no. 21 (2024): 5123. http://dx.doi.org/10.3390/molecules29215123.

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Corrosion of metallic equipment is a critical issue across various industries, necessitating the development of advanced protective strategies. This study utilized dispersion-corrected density functional theory (DFT) with Becke–Johnson D3(BJ) to examine the atomic-level adsorption of quinoxalinones on Fe(110) surfaces, focusing on optimizing substitution strategies to enhance corrosion inhibition. Three quinoxalinones, quinoxalin-2(1H)-one (QNO), 3-methylquinoxalin-2(1H)-one (QNOM), and 3,7-dimethylquinoxalin-2(1H)-one (QNO2M), were investigated in various configurations and protonation states
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Lv, Min, and Hui Xu. "The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols." Combinatorial Chemistry & High Throughput Screening 13, no. 3 (2010): 293–301. http://dx.doi.org/10.2174/138620710790980513.

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El-Telbani, Emad M., Ibrahim Radini, and Sameh R. Elgogary. "Syntheses of tricyclic fused quinoxaline ring systems: Pyrazoloquinoxalines (a-review)." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 35, no. 02 (2025): 279. https://doi.org/10.59467/ijhc.2025.35.279.

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Quinoxaline derivatives have gained significant interest due to their diverse pharmacological activity and have been included in numerous marketed drugs used to treat of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi), Balversa (L01EX16) (erdafitinib), carbadox, XK469R (NSC698215), and becampanel (AMP397). Among the five-membered fused tricyclic quinoxalines ring systems, the pyrazoloquinolines belong to the azaheterocyclic group as derivatives of quinoxalines and pyrazoles and have characterized by many biological and pharmaceutical properties. There are three
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El-Sawy, Eslam, Fatma Bassyouni, Sherifa Abu-Bakr, Hanaa Rady, and Mohamed Abdlla. "Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivatives." Acta Pharmaceutica 60, no. 1 (2010): 55–71. http://dx.doi.org/10.2478/v10007-010-0004-0.

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Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivativesStarting from 1-benzyl- (2a) and 1-benzoyl-3-bromoacetyl indoles (2b) new heterocyclic, 2-thioxoimidazolidine (4a, b), imidazolidine-2,4-dione (5a, b), pyrano(2,3-d)imida-zole (8a, band9a, b), 2-substituted quinoxaline (11a, b-17a, b) and triazolo(4,3-a)quinoxaline derivatives (18a, band19a, b) were synthesized and evaluated for their antimicrobial and anticancer activities. Antimicrobial activity screening performed with concentrations of 0.88, 0.44 and 0.22 μg mm-2showed that 3-(1-substitute
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Lv, Min, and Hui Xu. "ChemInform Abstract: The Combinatorial Synthesis of Bioactive Quinoxalines, Quinoxalinones and Quinoxalinols." ChemInform 41, no. 28 (2010): no. http://dx.doi.org/10.1002/chin.201028227.

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Chaouiki, Abdelkarim, Maryam Chafiq, Mohamed Rbaa, et al. "New 8-Hydroxyquinoline-Bearing Quinoxaline Derivatives as Effective Corrosion Inhibitors for Mild Steel in HCl: Electrochemical and Computational Investigations." Coatings 10, no. 9 (2020): 811. http://dx.doi.org/10.3390/coatings10090811.

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There has been substantial research undertaken on the role of green synthesized corrosion inhibitors as a substantial approach to inhibit the corrosion of metals and their alloys in acidic environments. Herein, electrochemical studies, surface characterization, and theoretical modeling were adopted to investigate the corrosion inhibition proprieties of novel synthesized quinoxaline derivatives bearing 8-Hydroxyquinoline, namely 1-((8-hydroxyquinolin-5-yl) methyl)-3,6-dimethylquinoxalin-2(1H)-one (Q1) and 1-((8-hydroxyquinolin-5-yl)methyl) quinoxalin-2(1H)-one (Q2) on mild steel corrosion in 1
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Elgogary, Sameh R., Emad M. El-Telbani, and Ibrahim Radini. "Syntheses and Biological Activities of Tricyclic-fused Quinoxaline Ring Systems (A Review). Part I: Thienoquinoxalines." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 02 (2024): 173. http://dx.doi.org/10.59467/ijhc.2024.34.173.

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Quinoxaline derivatives are an interesting class of heterocyclic compounds in drug discovery. It is rare in natural state, but their synthesis is easy to perform coupling between benzene and pyrazine rings. In addition, quinoxaline nucleus has received notable attention as an important pharmacophore that has broad-spectrum applications, especially in the fields of pharmaceutics and medicine. This review spotlights the biological activities and the different methods of preparation of three isomers of thienoquinoxalines, namely thieno[2,3-b]quinoxaline, thieno[3,4-b]quinoxaline, and thieno[2,3-g
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Rodriguez-Afanado, Michael Daniela, Fabian Lopez-Vallejo, Cristian Ochoa-Puentes, Luz M. Salazar, and Carlos Yesid Soto. "Pyrrolo[1,2-a]quinoxalinic Core-Derived Compounds Targeting the Mycobacterium tuberculosis P-type ATPase Plasma Membrane Ca2+ Transporter, CtpF, as Potential Antituberculous Drugs." International Journal of Mycobacteriology 14, no. 1 (2025): 10–23. https://doi.org/10.4103/ijmy.ijmy_197_24.

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Background: The resistance of Mycobacterium tuberculosis (Mtb) on first- and second-line anti-tuberculosis (TB) drugs is an issue for TB control; therefore, developing new anti-TB drugs is a priority in TB research. In this sense, the Ca2+ P-type ATPase plasma membrane transporter CtpF is an interesting anti-TB drug target. Methods: In this work, the activity of 4C-substituted pyrrolo[1,2-a]quinoxalinic compounds on Mtb viability and Ca2+ ATPase activity mediated by the plasma membrane transporter, CtpF, was assessed. The pyrrolo[1,2-a]quinoxalines compounds were initially in silico and analyz
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Dissertations / Theses on the topic "Quinoxalinon"

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Estevez, Yannick. "Activité leishmanicide de plantes issues de la pharmacopée traditionnelle Péruvienne et de molécules de synthèse : étude relation structure activité." Phd thesis, Université Paul Sabatier - Toulouse III, 2009. http://tel.archives-ouvertes.fr/tel-00519174.

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Les Leishmanioses du nouveau monde sont des parasitoses aux conséquences socio-économiques lourdes. En effet les traitements disponibles requièrent pour la plus part des administrations parentérales et sont coûteux pour les populations concernées. La recherche de nouvelles molécules actives est donc une nécessité. Pour contribuer à l'effort de recherche d'alternative thérapeutiques, nous nous sommes intéressés d'une part aux pharmacopées traditionnelles de populations vivant en zone d'endémie (deux ethnies de l'Amazonie péruvienne : Chayahuita et Yanesha) et d'autre part, nous avons également
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Poola, Bhaskar. "Synthesis and characterization of quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers and reaction chemistry of the diphosphine ligand 2,3-bis(diphenylphosphino)-N-p-tolylmaleimide (bmi) at triosmium carbonyl clusters." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5608/.

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Quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers have been synthesized as possible specific metal host systems. The synthesis and characterization of quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers have been described. The characterization of these host systems have been fully achieved in solution by using various techniques such as IR, 1H NMR, and 13C NMR spectroscopic methods, high-resolution mass spectrometry (HRMS), elemental microanalysis, and X-ray crystallographic analysis in case of one quinoxaline-functionalized, cage-annulated oxacrown ether c
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Wiethan, Carson Wanderley. "Síntese e funcionalização de azóis via formação de ligações carbono – carbono e carbono – nitrogênio." Universidade Federal de Santa Maria, 2017. http://repositorio.ufsm.br/handle/1/12456.

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This work describes the synthesis and functionalization of azoles employing different methodologies, based on organometallic catalysis or not. Firstly, we disclose the synthesis tetra-substituted 5-trifluoromethyl pyrazoles via sequential halogenation of 5-trifluoromethyl pyrazoles and palladium-catalyzed carbon–carbon and carbon–nitrogen cross-coupling reactions employing organozinc reagents and amines as coupling partners, respectively. This work allowed to achieve new pyrazolic systems in moderated to good yields. Posteriorly, we show the synthesis of 1,3-di(hetero)aryl indazoles exploring
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Coez, Arnaud. "Synthèse de quinoxaline-2,3-dione." Paris 5, 1992. http://www.theses.fr/1992PA05P117.

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Dihrkop, Erik. "Routes to Sydno[3,4-a]Quinoxalines." Wright State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=wright1291504978.

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Guillon, Jean. "Contribution à l'étude de nouvelles pyrrolo [1,2-α] quinoxalines : potentiels antagonistes non-peptidiques du récepteur au glucagon". Caen, 1996. http://www.theses.fr/1996CAEN4058.

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Howells, Ian Robert. "Synthetic studies on 1H-azepines benzimidazoles and quinoxalines." Thesis, University of Salford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308171.

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Blache, Yves. "Hétérocyclisation en séries quinoxalinique et pyrido[2,3-b]pyrazinique : synthèse, structure, réactivité." Montpellier 1, 1991. http://www.theses.fr/1991MON13508.

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Wu, Xianghong Gorden Anne Elizabeth. "Synthesis and applications of 2-quinoxalinol salens and their metal complexes." Auburn, Ala., 2008. http://hdl.handle.net/10415/1425.

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Zamudio, Vázquez Rubí. "Synthesis, Biological Evaluation and Insights into the Mode of Action of Quinoxaline Containing Peptides." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/132249.

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Triostins are members of the quinoxaline antibiotic family, together with the "prototypical bisintercalator" echinomycin. These molecules display interesting antitumour activities as they inhibit transcription through insertion of their two planar quinoxaline rings into the DNA double helix, spanning two base pairs, while the peptide backbone is placed in the minor groove. The main objective of this Doctoral Thesis has been the design, synthesis and characterization of novel compounds with antitumoral activity, taking as basis the chemical structure of the natural bisintercalator triostin
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Books on the topic "Quinoxalinon"

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Brown, D. J. Quinoxalines. John Wiley & Sons, Inc., 2004. http://dx.doi.org/10.1002/0471533408.

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Mamedov, Vakhid A. Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6.

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Ashcroft, Martin John. Quinoxaline-2,3-dithiolate and its metal complexes. University of Manchester, 1994.

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Howells, Ian Robert. Synthetic studies on 1H-azepines benzimidazoles and quinoxalines. University of Salford, 1996.

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Ahmad, Abid Rafiq. Studies of novel diazanaphthoquinones and ion-responsive fluorescent quinoxaline derivatives. Brunel University, 1994.

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Quinoxalines. Wiley, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines Vol. 61. Wiley & Sons, Incorporated, John, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines, Spplement 2. Wiley & Sons, Incorporated, John, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines, Spplement 2. Wiley & Sons, Incorporated, John, 2008.

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Mamedov, Vakhid A. Quinoxalines: Synthesis, Reactions, Mechanisms and Structure. Springer, 2018.

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Book chapters on the topic "Quinoxalinon"

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Mamedov, Vakhid A. "Quinoxaline–As a Parent Heterocycle." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_1.

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Mamedov, Vakhid A. "Synthesis of Quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_2.

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Mamedov, Vakhid A. "Synthesis of Pyrrolo[l,2-a]quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_3.

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Mamedov, Vakhid A. "Synthesis of Imidazo[1,5-a]- and Imidazo[1,2-a]quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_4.

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Mamedov, Vakhid A. "Synthesis of Quinoxaline Macrocycles." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_5.

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Mamedov, Vakhid A. "Rearrangements of Quinoxalin(on)es for the Synthesis of Benzimidazol(on)es." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_6.

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Waring, Michael J. "Echinomycin and Related Quinoxaline Antibiotics." In Molecular Aspects of Anticancer Drug-DNA Interactions. Macmillan Education UK, 1993. http://dx.doi.org/10.1007/978-1-349-12356-8_7.

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Plé, Nelly, and Corinne Fruit. "Metalation of Pyrazine and Quinoxaline." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_95.

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Pilato, Robert S., K. Eriksen, M. A. Greaney, et al. "Pterins, Quinoxalines, and Metallo-Ene-Dithiolates." In ACS Symposium Series. American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1993-0535.ch006.

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Jadhavar, Pradeep S., Dinesh Kumar, Priyank Purohit, et al. "Sustainable Approaches Towards the Synthesis of Quinoxalines." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_2.

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Conference papers on the topic "Quinoxalinon"

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Ouedghiri-Idrissi, I. E., Z. Sofiani, A. Talbi, et al. "Photophysical study of 2,3-Diphenyl Quinoxaline thin films for potential applications in optoelectronic devices." In 2024 24th International Conference on Transparent Optical Networks (ICTON). IEEE, 2024. http://dx.doi.org/10.1109/icton62926.2024.10647382.

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Knorr, Erica S., Jordan C. Kelly, Daniel P. Harrison, and Thomas N. Rohrabaugh. "Effect of electron-donating and -withdrawing groups on the photophysical properties of iridium (iii) diphenyl quinoxaline complexes." In Organic Photonic Materials and Devices XXVII, edited by Ileana Rau, Okihiro Sugihara, and William M. Shensky. SPIE, 2025. https://doi.org/10.1117/12.3047905.

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"SEARCH FOR DRUG PROTOTYPES FOR NMDA- AND AMPA-RECEPTOR ANTAGONISTS AMONG QUINOXALINE AND PYRAZINOBENZIMIDAZOLE DERIVATIVES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-319.

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The project is dedicated to screening of ionotropic glutamate receptors inhibitors among pyrazinobenzimidazole and quinoxaline derivatives. The pyramidal neurons of the hippocampus of Wistar rat brain were used for the study. With the patch clamp technique, we found the most active compound — this is a representative of the quinoxaline class with the code name ZDM-15.
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Popović-Nikolić, Marija R., Katarina Nikolić, and Mara Aleksić. "DFT approach of the redox properties of brimonidine and varenicline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.423pn.

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The redox properties of two quinoxaline derivatives, brimonidine and varenicline, previously studied electrochemically, were evaluated by performing a computational study. On the basis of some useful quantum chemical parameters the differences and similarities between their redox features were explained. The obtained results support the experimental findings that the redox processes of both compounds are under strong influence of the solution pH, whereas the reduction of brimonidine occurs easier than the reduction of varenicline, at corresponding pH values.
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Ferreira, Samuel R. A., Jesus M. Pena, Simone C. Silva, and Giuliano C. Clososki. "Directed Functionalization of Quinoxalines Aiming the Synthesis of Bioactive Compounds." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201391317050.

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Lee, Young Bok, Gina Chun, Deog J. Kim, et al. "Abstract 1371: Antitumor activity of a new quinoxalinyl-piperazine compound." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1371.

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Li, Yang, and Bing Ma. "Study on Aldose Reductase Inhibitors Based on Quinoxalin Structure." In 2018 International Workshop on Bioinformatics, Biochemistry, Biomedical Sciences (BBBS 2018). Atlantis Press, 2018. http://dx.doi.org/10.2991/bbbs-18.2018.29.

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Sushma, G. N., M. Suma, A. G. Pramod, and Y. F. Nadaf. "Structural, thermal, chemical and optoelectronic properties of the quinoxaline with DFT." In 3RD INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0002148.

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Deva, Liliia, Iryna Yaremchuk, Tetiana Bulavinets, et al. "Yellow-green high-efficiency TADF OLED with phenoxazine and quinoxaline as emitter." In RAD Conference. RAD Centre, 2023. http://dx.doi.org/10.21175/rad.abstr.book.2023.14.3.

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Tzu-Chau Lin, Ying-Hsuan Lee, Che-Yu Liu, Ja-Hon Lin, and Yu-Kai Shen. "Synthesis and two-photon properties of small dendritic chromophores containing functionalized quinoxalinoid heterocycles." In 2013 Conference on Lasers and Electro-Optics Pacific Rim (CLEO-PR). IEEE, 2013. http://dx.doi.org/10.1109/cleopr.2013.6600509.

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